90 results on '"Yunpeng Ding"'
Search Results
2. Primary cilia support cartilage regeneration after injury
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Dike Tao, Lei Zhang, Yunpeng Ding, Na Tang, Xiaoqiao Xu, Gongchen Li, Pingping Niu, Rui Yue, Xiaogang Wang, Yidong Shen, and Yao Sun
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Dentistry ,RK1-715 - Abstract
Abstract In growing children, growth plate cartilage has limited self-repair ability upon fracture injury always leading to limb growth arrest. Interestingly, one type of fracture injuries within the growth plate achieve amazing self-healing, however, the mechanism is unclear. Using this type of fracture mouse model, we discovered the activation of Hedgehog (Hh) signaling in the injured growth plate, which could activate chondrocytes in growth plate and promote cartilage repair. Primary cilia are the central transduction mediator of Hh signaling. Notably, ciliary Hh-Smo-Gli signaling pathways were enriched in the growth plate during development. Moreover, chondrocytes in resting and proliferating zone were dynamically ciliated during growth plate repair. Furthermore, conditional deletion of the ciliary core gene Ift140 in cartilage disrupted cilia-mediated Hh signaling in growth plate. More importantly, activating ciliary Hh signaling by Smoothened agonist (SAG) significantly accelerated growth plate repair after injury. In sum, primary cilia mediate Hh signaling induced the activation of stem/progenitor chondrocytes and growth plate repair after fracture injury.
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- 2023
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3. Research on Surface Roughness of Supersonic Vibration Auxiliary Side Milling for Titanium Alloy
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Xuetao Wei, Caixu Yue, Desheng Hu, Xianli Liu, Yunpeng Ding, and Steven Y. Liang
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Side milling ,Axial vibration ,Ultrasonic milling ,Finite element simulation ,Linear regression ,Surface roughness ,Ocean engineering ,TC1501-1800 ,Mechanical engineering and machinery ,TJ1-1570 - Abstract
Abstract The processed surface contour shape is extracted with the finite element simulation software. The difference value of contour shape change is used as the parameters of balancing surface roughness to construct finite element model of supersonic vibration milling in cutting stability domain. The surface roughness trial scheme is designed in the orthogonal test design method to analyze the surface roughness test result in the response surface methodology. The surface roughness prediction model is established and optimized. Finally, the surface roughness finite element simulation prediction model is verified by experiments. The research results show that, compared with the experiment results, the error range of the finite element simulation model is 27.5%–30.9%, and the error range of the empirical model obtained by the response surface method is between 4.4% and 12.3%. So, the model in this paper is accurate and will provide the theoretical basis for the optimization study of the auxiliary milling process of supersonic vibration.
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- 2022
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4. Tracing PRX1+ cells during molar formation and periodontal ligament reconstruction
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Xuyan Gong, Han Zhang, Xiaoqiao Xu, Yunpeng Ding, Xingbo Yang, Zhiyang Cheng, Dike Tao, Congjiao Hu, Yaozu Xiang, and Yao Sun
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Dentistry ,RK1-715 - Abstract
Abstract Neural crest-derived mesenchymal stem cells (MSCs) are known to play an essential function during tooth and skeletal development. PRX1+ cells constitute an important MSC subtype that is implicated in osteogenesis. However, their potential function in tooth development and regeneration remains elusive. In the present study, we first assessed the cell fate of PRX1+ cells during molar development and periodontal ligament (PDL) formation in mice. Furthermore, single-cell RNA sequencing analysis was performed to study the distribution of PRX1+ cells in PDL cells. The behavior of PRX1+ cells during PDL reconstruction was investigated using an allogeneic transplanted tooth model. Although PRX1+ cells are spatial specific and can differentiate into almost all types of mesenchymal cells in first molars, their distribution in third molars is highly limited. The PDL formation is associated with a high number of PRX1+ cells; during transplanted teeth PDL reconstruction, PRX1+ cells from the recipient alveolar bone participate in angiogenesis as pericytes. Overall, PRX1+ cells are a key subtype of dental MSCs involved in the formation of mouse molar and PDL and participate in angiogenesis as pericytes during PDL reconstruction after tooth transplantation.
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- 2022
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5. Comparison of Fish, Krill and Flaxseed as Omega-3 Sources to Increase the Omega-3 Index in Dogs
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Hanna Lindqvist, Tonje Dominguez, Ragnhild Dragøy, Yunpeng Ding, and Lena Burri
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docosahexaenoic acid ,dog ,eicosapentaenoic acid ,krill meal ,omega-3 index ,premium dog food ,Veterinary medicine ,SF600-1100 - Abstract
(1) Background: it is only the longer chain omega-3 polyunsaturated fatty acids (n-3 PUFAs), eicosapentaenoic acid (20:5n-3, EPA), and docosahexaenoic acid (22:6n-3, DHA) and not the shorter chain α-linolenic acid (ALA, 18:3n-3) that have been linked to health benefits. (2) Methods: 45 dogs divided into three groups were first given premium dry food for 38 days (baseline). The O3I was then used as a diagnostic tool to provide a measure of the sum of EPA + DHA in red blood cell membranes given as a percentage of all fatty acids. The dogs were subsequently fed with either krill meal (krill), fishmeal/oil (fish) or flaxseed cake (flax) included in raw food providing daily 416 mg EPA + DHA (971 mg ALA), 513 mg EPA + DHA (1027 mg ALA) and 1465 mg ALA (122 mg EPA + DHA), respectively. (3) Results: the average baseline O3I level of all dogs was low (1.36%), warranting n-3 supplementation. After four weeks, O3I levels were significantly increased in the krill (from 1.36 ± 0.44 to 2.36 ± 0.39%) and fish (from 1.35 ± 0.22 to 1.9 ± 0.35%) groups (p < 0.001). No significant modification of the O3I was detected in the flax animals. (4) Conclusions: only marine n-3 PUFAs resulted in a significantly increased O3I, with dietary krill meal providing the highest increase.
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- 2023
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6. Strengthening and Toughening CNTs/Mg Composites by OpTimizing the Grinding Time of Magnesium Powder
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Yunpeng Ding, Yizhuang Zhang, Zhiyuan Li, Changhong Liu, Hanying Wang, Xin Zhao, Xinfang Zhang, Jilei Xu, and Xiaoqin Guo
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carbon nanotube ,magnesium matrix nanocomposite ,strengthening ,toughening ,mechanical property ,Chemistry ,QD1-999 - Abstract
In this paper, CNT/Mg composites with high compressive properties were prepared by using Ni-plated CNT and pure magnesium powder as raw materials through the grinding of magnesium powder, ball-milling mixing and hot-pressing sintering. The effect of grinding time for finer magnesium powder on the microstructure and properties of the final composites was studied mainly by SEM, XRD, HRTEM and compression tests. The results show that with the prolongation of milling time, the magnesium particle size decreases gradually and the CNT dispersion becomes more uniform. Moreover, the nickel layer on the surface of CNT reacts with highly active broken magnesium powder in the sintering process to generate MgNi2 intermediate alloy, which significantly improves interface bonding. The strength and fracture strain of composites are significantly increased by the combined action of the uniform distribution of CNTs and strong interface bonding from the MgNi2 phase. The compressive strength, yield strength and fracture strain of the composites, prepared with a 60 h grinding of magnesium powder, reached 268%, 272% and 279% of those in composites without the grinding of magnesium powder.
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- 2022
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7. Strengthening Ni-Coated CNT/Mg Composites by Optimizing the CNT Content
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Jilei Xu, Yizhuang Zhang, Zhiyuan Li, Yunpeng Ding, Xin Zhao, Xinfang Zhang, Hanying Wang, Changhong Liu, and Xiaoqin Guo
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carbon nanotube ,magnesium matrix nanocomposite ,strengthening ,strong interface bonding ,mechanical property ,Chemistry ,QD1-999 - Abstract
The dispersion of carbon nanotubes (CNTs) is the bottleneck in CNT-reinforced metal matrix composites. In this work, CNT/Mg composites were prepared by grinding Mg powder and then dispersing CNTs via ball milling and hot pressing. The uniform distribution of Ni-coated CNTs in the matrix was achieved by optimizing the content of CNTs. Scanning electron microscope, high-resolution transmission electron microscopy and X-ray diffraction, optical microscopy, and compression tests were employed. With the CNT content being less than 1%, the CNTs can be evenly distributed in CNT/Mg composites, resulting in a sharp increase in strength. However, with the higher CNT content, the CNTs gradually cluster, leading decreased fracture strain and strength. Furthermore, the coated Ni in the CNTs reacts with the magnesium matrix and completely transforms into Mg2Ni, significantly enhancing the interface bonding. This strong interface bonding and the diffusely distributed Mg2Ni in the matrix significantly strengthen the CNT/Mg composite.
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- 2022
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8. Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, 1-year follow-up: a cluster-randomised trial
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Allen Nsangi, Daniel Semakula, Andrew D. Oxman, Astrid Austvoll-Dahlgren, Matt Oxman, Sarah Rosenbaum, Angela Morelli, Claire Glenton, Simon Lewin, Margaret Kaseje, Iain Chalmers, Atle Fretheim, Yunpeng Ding, and Nelson K. Sewankambo
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Evidence-based healthcare ,Training ,Critical thinking ,Health literacy ,Informed decision-making ,Public involvement ,Medicine (General) ,R5-920 - Abstract
Abstract Introduction We evaluated an intervention designed to teach 10- to 12-year-old primary school children to assess claims about the effects of treatments (any action intended to maintain or improve health). We report outcomes measured 1 year after the intervention. Methods In this cluster-randomised trial, we included primary schools in the central region of Uganda that taught year 5 children (aged 10 to 12 years). We randomly allocated a representative sample of eligible schools to either an intervention or control group. Intervention schools received the Informed Health Choices primary school resources (textbooks, exercise books and a teachers’ guide). The primary outcomes, measured at the end of the school term and again after 1 year, were the mean score on a test with two multiple-choice questions for each of the 12 concepts and the proportion of children with passing scores. Results We assessed 2960 schools for eligibility; 2029 were eligible, and a random sample of 170 were invited to recruitment meetings. After recruitment meetings, 120 eligible schools consented and were randomly assigned to either the intervention group (n = 60 schools; 76 teachers and 6383 children) or the control group (n = 60 schools; 67 teachers and 4430 children). After 1 year, the mean score in the multiple-choice test for the intervention schools was 68.7% compared with 53.0% for the control schools (adjusted mean difference 16.7%; 95% CI, 13.9 to 19.5; P
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- 2020
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9. Influence of Soft Phase and Carbon Nanotube Content on the Properties of Hierarchical AZ61 Matrix Composite with Isolated Soft Phase
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Yunpeng Ding, Sijia Jiao, Yizhuang Zhang, Zhiai Shi, Jinbiao Hu, Xulei Wang, Zhiyuan Li, Hanying Wang, and Xiaoqin Guo
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carbon nanotube ,hierarchical magnesium matrix composite ,soft phase ,microstructure ,mechanical property ,Chemistry ,QD1-999 - Abstract
Carbon nanotube-reinforced magnesium matrix (CNTs/Mg) composite has great application potential in the transportation industry, but the trade-off between strength and ductility inhibits its widespread application. In order to balance the strength and plasticity of the composite, in this work, on the basis of the AZ61 matrix composite homogeneously reinforced by Ni-coated CNTs (hard phase), 30 vol.% large-size AZ61 particles are introduced as an isolated soft phase to fabricate hierarchical CNTs/AZ61 composites. The compression tests show the fracture strain and compressive strength of this composite increases by 54% and 8%, respectively, compared with homogeneous CNTs/AZ61 composite. During deformation, the hard phase is mainly responsible for bearing the load and bringing high strength, due to the precipitation of the Mg17Al12 phase, uniformly dispersed CNT and strong interfacial bonding of the CNTs/Mg interface through nickel plating and interfacial chemical reaction. Furthermore, the toughening of the soft phase results in high ductility. With the increase in CNT content, the compressive strength of composites is nearly unchanged but the fracture strain gradually decreases due to the stress concentration of CNT and its agglomeration.
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- 2022
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10. Effect of Foliar Application of Various Nitrogen Forms on Starch Accumulation and Grain Filling of Wheat (Triticum aestivum L.) Under Drought Stress
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Xiaokang Lv, Yunpeng Ding, Mei Long, Wenxin Liang, Xiaoyan Gu, Yang Liu, and Xiaoxia Wen
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nitrogen ,water deficit ,grain weight ,starch biosynthesis ,hormone ,antioxidant activity ,Plant culture ,SB1-1110 - Abstract
Foliar nitrogen (N) fertilizer application at later stages of wheat (Triticum aestivum L.) growth is an effective method of attenuating drought stress and improving grain filling. The influences or modes of action of foliar application of various nitrogen forms on wheat growth and grain filling need further research. The objective of this study was to examine the regulatory effects of various forms of foliar nitrogen [NO3–, NH4+, and CO(NH2)2] on wheat grain filling under drought stress and to elucidate their underlying mechanisms. The relative effects of each nitrogen source differed in promoting grain filling. Foliar NH4+-N application notably prolonged the grain filling period. In contrast, foliar application of CO(NH2)2 and NO3–-N accelerated the grain filling rate and regulated levels of abscisic acid (ABA), z-riboside (ZR), and ethylene (ETH) in wheat grains. Analysis of gene expression revealed that CO(NH2)2 and NO3–-N upregulated the genes involved in the sucrose–starch conversion pathway, promoting the remobilization of carbohydrates and starch synthesis in the grains. Besides, activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) were increased, whereas the content of malondialdehyde (MDA) declined under foliar nitrogen application (especially NH4+-N). Under drought stress, enhancement of carbohydrate remobilization and sink strength became key factors in grain filling, and the relative differences in the effects of three N forms became more evident. In conclusion, NH4+-N application improved the antioxidant enzyme system and delayed photoassimilate transportation. On the other hand, foliar applications of NO3–-N and CO(NH2)2 enhanced sink capacity and alleviated drought stress injury in wheat.
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- 2021
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11. Effect of CNT Content on Microstructure and Properties of CNTs/Refined-AZ61 Magnesium Matrix Composites
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Yunpeng Ding, Zhiai Shi, Zhiyuan Li, Sijia Jiao, Jinbiao Hu, Xulei Wang, Yizhuang Zhang, Hanying Wang, and Xiaoqin Guo
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carbon nanotube ,magnesium matrix nanocomposite ,hot oscillatory pressing ,mechanical property ,Chemistry ,QD1-999 - Abstract
Carbon nanotubes (CNTs) reinforced magnesium matrix composites have great application potential in the transportation industry, but the low absolute strength is the main obstacle to its application. In this paper, copper-coated CNTs and AZ61 powder were used as raw materials to prepare CNTs/refined-AZ61 composites with good interfacial bonding, uniformly dispersed CNTs and fine grains by the process of ball milling refinement of AZ61 powder, ball milling dispersion and hot-pressing sintering. When the volume fraction of CNTs is less than or equal to 1 vol.%, CNTs can be uniformly dispersed and the yield strength and compressive strength of composites increase with higher CNT content. When the volume fraction of CNTs is 1 vol.%, the compressive strength and yield strength of composites reach 439 MPa and 361 MPa, respectively, which are 14% and 9% higher than those of matrix composites with nearly the same value of fracture strain. When the volume fraction of CNTs is greater than 1 vol.%, with the increase in CNT content, CNT clustering becomes more and more serious, resulting in a decrease in the strength and fracture strain of composites.
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- 2022
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12. Characteristics and Antioxidant Activity of Walnut Oil Using Various Pretreatment and Processing Technologies
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Pan Gao, Yunpeng Ding, Zhe Chen, Zhangtao Zhou, Wu Zhong, Chuanrong Hu, Dongping He, and Xingguo Wang
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walnut oil ,pretreatment ,processing ,subcritical butane extraction ,steaming roasting ,Chemical technology ,TP1-1185 - Abstract
This study was the first time the effects of pretreatment technology (microwave roasting, MR; oven roasting, OR; steaming roasting, SR) and processing technology (screw pressing, SP; aqueous enzymatic extraction, AEE; subcritical butane extraction, SBE) on the quality (physicochemical properties, phytochemical content, and antioxidant ability) of walnut oil were systematically compared. The results showed that the roasting pretreatment would reduce the lipid yield of walnut oil and SBE (59.53–61.19%) was the processing method with the highest yield. SR-AEE oil provided higher acid value (2.49 mg/g) and peroxide value (4.16 mmol/kg), while MR-SP oil had the highest content of polyunsaturated fatty acid (73.69%), total tocopherol (419.85 mg/kg) and total phenolic compounds (TPC, 13.12 mg/kg). The DPPH-polar and ABTS free radicals’ scavenging abilities were accorded with SBE > AEE > SP. SBE is the recommended process for improving the extraction yield and antioxidant ability of walnut oil. Hierarchical cluster analysis showed that processing technology had a greater impact on walnut oil than pretreatment technology. In addition, multiple linear regression revealed C18:0, δ-tocopherol and TPC had positive effects on the antioxidant ability of walnut oil, while C18:1n-9, C18:3n-3 and γ-tocopherol were negatively correlated with antioxidant activity. Thus, this a promising implication for walnut oil production.
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- 2022
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13. Effect of Heat Treatment on Mechanical Properties and Fracture Behavior of Al-7.0Si-0.3Mg Alloy at Low Temperature
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Guanghui Ma, Mengmeng Yang, Zhe Geng, Yunpeng Ding, Hai Liu, and Yujing Jin
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Al-7.0Si-0.3Mg ,low temperature ,mechanical properties ,fracture behavior ,Crystallography ,QD901-999 - Abstract
In order to investigate the effect of heat treatment on the mechanical properties of the Al-7.0Si-0.3Mg alloy at 20–60 °C under different heat treatment processes, the tensile mechanical properties of Al-7.0Si-0.3Mg at low temperature after heat treatment were explored. The microstructure of Al-7.0Si-0.3Mg was observed by scanning electron microscopy (SEM) and transmission electron microscopy. The results show that the resistance of the dislocation movement in α-Al increased in the low-temperature condition, which is beneficial for the number of Si phase fractures that increase to enhance the tensile strength and weaken the elongation of the Al-7.0Si-0.3Mg alloy. After the solution treatment, the particle size of the Si phase reduced, while the morphology became rounded. In the early stage of aging, a GP region is generated inside the α-Al. With the prolonging of aging time, the acicular β″ phase is formed and then grows into rod-shaped β′. In the overaging stage, β′ eventually grows into flaky β. Due to the different linear expansion coefficients of the α-Al and the Mg2Si phase in the Al-7.0Si-0.3Mg alloy, the α-Al is squeezed by the Mg2Si phase under the effect of low-temperature shrinkage.
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- 2022
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14. A comparative evaluation of PDQ-Evidence
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Marit Johansen, Gabriel Rada, Sarah Rosenbaum, Elizabeth Paulsen, Nkengafac Villyen Motaze, Newton Opiyo, Charles S. Wiysonge, Yunpeng Ding, Fidele K. Mukinda, and Andrew D. Oxman
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Health policy ,Health systems ,Systematic reviews ,Evidence-informed health policy ,Comparative study ,Bibliographic databases ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background A strategy for minimising the time and obstacles to accessing systematic reviews of health system evidence is to collect them in a freely available database and make them easy to find through a simple ‘Google-style’ search interface. PDQ-Evidence was developed in this way. The objective of this study was to compare PDQ-Evidence to six other databases, namely Cochrane Library, EVIPNet VHL, Google Scholar, Health Systems Evidence, PubMed and Trip. Methods We recruited healthcare policy-makers, managers and health researchers in low-, middle- and high-income countries. Participants selected one of six pre-determined questions. They searched for a systematic review that addressed the chosen question and one question of their own in PDQ-Evidence and in two of the other six databases which they would normally have searched. We randomly allocated participants to search PDQ-Evidence first or to search the two other databases first. The primary outcomes were whether a systematic review was found and the time taken to find it. Secondary outcomes were perceived ease of use and perceived time spent searching. We asked open-ended questions about PDQ-Evidence, including likes, dislikes, challenges and suggestions for improvements. Results A total of 89 people from 21 countries completed the study; 83 were included in the primary analyses and 6 were excluded because of data errors that could not be corrected. Most participants chose PubMed and Cochrane Library as the other two databases. Participants were more likely to find a systematic review using PDQ-Evidence than using Cochrane Library or PubMed for the pre-defined questions. For their own questions, this difference was not found. Overall, it took slightly less time to find a systematic review using PDQ-Evidence. Participants perceived that it took less time, and most participants perceived PDQ-Evidence to be slightly easier to use than the two other databases. However, there were conflicting views about the design of PDQ-Evidence. Conclusions PDQ-Evidence is at least as efficient as other databases for finding health system evidence. However, using PDQ-Evidence is not intuitive for some people. Trial registration The trial was prospectively registered in the ISRCTN registry 17 April 2015. Registration number: ISRCTN12742235.
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- 2018
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15. Hot Oscillatory Pressing of Carbon Nanotube-Reinforced Copper Matrix Nanocomposite
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Min Han, Yunpeng Ding, Jinbiao Hu, Zhiai Shi, Sijia Jiao, Xiaoqin Guo, Hanying Wang, and Linan An
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carbon nanotube ,copper matrix nanocomposite ,hot oscillatory pressing ,densification ,hardness ,Chemistry ,QD1-999 - Abstract
Carbon nanotube reinforced copper matrix nanocomposites have great potential in machinery, microelectronics, and other applications. The materials are usually prepared by powder metallurgy processes, in which consolidation is a key step for high performance. To improve the density and mechanical properties, the authors explored the use of hot oscillatory pressing (HOP) to prepare this material. A carbon nanotube reinforced copper matrix nanocomposite was synthesized by both HOP and hot pressing (HP) at various temperatures, respectively. The samples prepared by HOP exhibited significantly higher density and hardness than those prepared by HP at the same temperature, and this was because the oscillatory pressure of HOP produced remarkable plastic deformation in copper matrix during sintering. With the decrease of sintering temperature in HOP, the amount of deformation defect increased gradually, playing a key role in the increasing hardness. This work proves experimentally for the first time that HOP can produce much more plastic deformation than HP to promote densification, and that HOP could be a very promising technique for preparing high-performance carbon nanotube reinforced copper matrix nanocomposites.
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- 2021
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16. Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris
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Yunpeng Ding, Gard F. T. Svingen, Eva R. Pedersen, Jesse F. Gregory, Per M. Ueland, Grethe S. Tell, and Ottar K. Nygård
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amino acids ,apolipoprotein ,atherosclerosis ,glycine ,lipids and lipoprotein metabolism ,myocardial infarction ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundGlycine is an amino acid involved in antioxidative reactions, purine synthesis, and collagen formation. Several studies demonstrate inverse associations of glycine with obesity, hypertension, and diabetes mellitus. Recently, glycine‐dependent reactions have also been linked to lipid metabolism and cholesterol transport. However, little evidence is available on the association between glycine and coronary heart disease. Therefore, we assessed the association between plasma glycine and acute myocardial infarction (AMI). Methods and ResultsA total of 4109 participants undergoing coronary angiography for suspected stable angina pectoris were studied. Cox regression was used to estimate the association between plasma glycine and AMI, obtained via linkage to the CVDNOR project. During a median follow‐up of 7.4 years, 616 patients (15.0%) experienced an AMI. Plasma glycine was higher in women than in men and was associated with a more favorable baseline lipid profile and lower prevalence of obesity, hypertension, and diabetes mellitus (all P
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- 2016
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17. Web APIs recommendation with neural content embedding for mobile multimedia computing.
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Yueshen Xu, Yunpeng Ding, Zhiping Jiang, Yuyu Yin, Lei Hei, and Shaoyuan Zhang
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- 2023
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18. Geno: A Developer Tool for Authoring Multimodal Interaction on Existing Web Applications.
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Ritam Jyoti Sarmah, Yunpeng Ding, Di Wang, Cheuk Yin Phipson Lee, Toby Jia-Jun Li, and Xiang 'Anthony' Chen
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- 2020
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19. Preference discovery from wireless social media data in APIs recommendation.
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Yueshen Xu, He Zhang, Honghao Gao, Shengli Song, Yuyu Yin, Lei Hei, Yunpeng Ding, and Ramón J. Durán Barroso
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- 2021
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20. Study on the Ball-End Milling Cutter Design and the Performance of Milling SiCp/Al
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Yunpeng Ding, Jia Wang, Hongfeng Zhao, Guotong Feng, Yingqi Zhang, Ming Kong, and Erliang Liu
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Control and Systems Engineering ,Materials Chemistry ,Ceramics and Composites ,Electrical and Electronic Engineering ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials - Published
- 2023
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21. Mining Mobile Users' Interests Through Cellular Network Browsing Profiles.
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Fan Yan, Yunpeng Ding, and Wenzhong Li
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- 2018
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22. Hierarchically Structured Carbon Nanofiber-Enabled Skin-Like Strain Sensors with Full-Range Human Motion Monitoring and Autonomous Self-Healing Capability
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Guang Yang, Haojun Luo, Yunpeng Ding, Jingwen Yang, Yafang Li, Chongqi Ma, Jing Yan, and Xupin Zhuang
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General Materials Science - Published
- 2023
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23. Assessment of the Physicochemical Properties of Fragrant Rapeseed Blended Hotpot Oil by Principal Component Analysis
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Yunpeng Ding, Pan Gao, Yanni Mao, Hui Liu, Wu Zhong, Chuanrong Hu, Dongping He, and Xingguo Wang
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General Chemical Engineering ,General Medicine ,General Chemistry - Published
- 2023
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24. Web APIs recommendation with neural content embedding for mobile multimedia computing
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Yueshen Xu, Yunpeng Ding, Zhiping Jiang, Yuyu Yin, Lei Hei, and Shaoyuan Zhang
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Computer Networks and Communications ,Electrical and Electronic Engineering ,Information Systems - Published
- 2022
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25. Research on machining error prediction of open blade under dynamic loading
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Yunpeng Ding, Jianhua Chu, Jiju Guan, and Ming Kong
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Condensed Matter Physics ,Electronic, Optical and Magnetic Materials - Published
- 2022
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26. Experimental study on turning performance of a novel nanofluid prepared by composites of MWCNTs
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Chao Gao, Xu Zhengya, Zhiliang Wang, Guan Jiju, Yunpeng Ding, and Xuefeng Xu
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Materials science ,Mechanical Engineering ,Alloy steel ,engineering.material ,Industrial and Manufacturing Engineering ,Computer Science Applications ,Nanofluid ,Machining ,Control and Systems Engineering ,Dispersion stability ,Surface roughness ,Lubrication ,engineering ,Wetting ,Composite material ,Dispersion (chemistry) ,Software - Abstract
In this work, novel DPS/MWCNT composites were synthesized through filling multi-walled carbon nanotubes (MWCNTs) with dialkyl pentasulfide (DPS) using a wet-chemical method. A nanofluid that use the DPS/MWCNT composites as additives was then developed for achieving a high-performance turning. The performance of the developed nanofluid including dispersion stability, heat transfer capacity, and wettability was evaluated using thermophysical analytical methods. The machining performance of the DPS/MWCNT composites nanofluid was systematically investigated in the turning of AISI 52100 alloy steel, using a commercial emulsion coolant as a benchmark. The lubrication mechanism of the nanofluid involved in the turning process was reveal with the aid of X-ray photoelectron spectroscopy (XPS). The results showed that DPS was successfully filled into MWCNTs with a filling rate of around 25.7%. The nanofluid had an excellent dispersion performance and produced respective 105.0% and 23.6% improvements in the heat transfer and wetting performance, in comparison to a base fluid. During turning, the composites suspended in the nanofluid acted as microbearings to reduce the friction of sliding, while the DPS filled in the MWCNTs was released under pressure to generate a complex lubricating film at the tool-chip interface, leading to a low resistance to cutting. This thus resulted in 15% and 25% reductions in the cutting force and temperature as well as 16% and 22% improvements in the surface roughness and tool life, in comparison to a conventional turning.
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- 2021
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27. Overcome strength and toughness trade-off in Cu-decorated carbon nanotubes reinforced magnesium matrix composites by chemical reaction interface and grain refinement
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Yunpeng Ding, Yizhuang Zhang, Zhiyuan Li, Zhiai Shi, Xinfang Zhang, and Xiaoqin Guo
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Mechanics of Materials ,Mechanical Engineering ,General Materials Science ,Condensed Matter Physics - Published
- 2023
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28. Preference discovery from wireless social media data in APIs recommendation
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Lei Hei, Shengli Song, Yunpeng Ding, Yuyu Yin, Yueshen Xu, Ramón J. Durán Barroso, Honghao Gao, and He Zhang
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Word embedding ,Information retrieval ,Computer Networks and Communications ,Process (engineering) ,business.industry ,Computer science ,Software development ,020206 networking & telecommunications ,020302 automobile design & engineering ,Collaborative learning ,02 engineering and technology ,Preference ,Software ,0203 mechanical engineering ,0202 electrical engineering, electronic engineering, information engineering ,Social media ,Electrical and Electronic Engineering ,Representation (mathematics) ,business ,Information Systems - Abstract
In recent years, with the development of software development, a large number of developers develop software by invoking API. With the increasing number of APIs, how to accurately recommend the APIs to developers has become a urgently necessary task. In this paper, we discover that there is a relationship between the user and the API, and use such relationships and collaborative learning techniques to finish APIs recommendation. We propose a holistic framework that contains three models. In the models, we design a joint matrix factorization technique and try to discover the preference among APIs invocation process. In natural language processing, word embedding is widely used. In our models, we use doc2vec to turn the representation of users and APIs into vector representation and calculate the similarity separately to generate the relationships. Besides the two modes in users side and APIs side, we also propose an ensemble model fully leveraging the preference mined from both users side and APIs side. We conduct the experiments on a real-world dataset and the experimental results show that our models perform better than all compared methods.
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- 2021
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29. Krill-Oil-Dependent Increases in HS-Omega-3 Index, Plasma Choline and Antioxidant Capacity in Well-Conditioned Power Training Athletes
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Montserrat Banquells, Per Björk, Lena Burri, Franchek Drobnic, Ventura Ferrer-Roca, Joan Carles Domingo, Andreas Berg Storsve, Joan Lluís Riera, and Yunpeng Ding
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Male ,CrossFitTM ,Antioxidants ,chemistry.chemical_compound ,choline ,power training ,DHA ,EPA ,high-intensity interval training ,krill oil ,HS-Omega-3 Index ,oxidative stress ,phosphatidylcholine ,sports nutrition ,Choline ,Medicine ,TX341-641 ,chemistry.chemical_classification ,Nutrition and Dietetics ,biology ,Nutrition of athletes ,Healthy Volunteers ,Female ,Citidina difosfat de colina ,High-intensity interval training ,Polyunsaturated fatty acid ,Adult ,Krill ,Estrès oxidatiu ,Athletic Performance ,Sports nutrition ,Placebo ,Krill oil ,Article ,Fish Oils ,Animal science ,Double-Blind Method ,Phosphatidylcholine ,Fatty Acids, Omega-3 ,Animals ,Humans ,Cytidine diphosphate choline ,business.industry ,Nutrition. Foods and food supply ,biology.organism_classification ,Alimentació dels esportistes ,chemistry ,Oxidative stress ,Dietary Supplements ,business ,Euphausiacea ,Food Science - Abstract
There is evidence that both omega-3 polyunsaturated fatty acids (n-3 PUFAs) and choline can influence sports performance, but information establishing their combined effects when given in the form of krill oil during power training protocols is missing. The purpose of this study was therefore to characterize n-3 PUFA and choline profiles after a one-hour period of high-intensity physical workout after 12 weeks of supplementation. Thirty-five healthy power training athletes received either 2.5 g/day of Neptune krill oilTM (550 mg EPA/DHA and 150 mg choline) or olive oil (placebo) in a randomized double-blind design. After 12 weeks, only the krill oil group showed a significant HS-Omega-3 Index increase from 4.82 to 6.77% and a reduction in the ARA/EPA ratio (from 50.72 to 13.61%) (p < 0.001). The krill oil group showed significantly higher recovery of choline concentrations relative to the placebo group from the end of the first to the beginning of the second exercise test (p = 0.04) and an 8% decrease in total antioxidant capacity post-exercise versus 21% in the placebo group (p = 0.35). In conclusion, krill oil can be used as a nutritional strategy for increasing the HS-Omega-3 Index, recover choline concentrations and address oxidative stress after intense power trainings.
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- 2021
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30. Vertebral artery course variation leading to an insufficient proximal anchoring area for thoracic endovascular aortic repair
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Zuanbiao Yu, Shuyi Lyu, Dehai Lang, Di Wang, Songjie Hu, Xiaoliang Yin, Yunpeng Ding, Chunbo Xu, Chen Lin, and Jiangnan Hu
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Radiology, Nuclear Medicine and imaging ,Surgery ,General Medicine ,Cardiology and Cardiovascular Medicine - Abstract
Backgrounds We aimed to demonstrate the feasibility of thoracic endovascular aortic repair for type B aortic dissection in patients with an insufficient proximal anchoring area due to the vertebral artery originating from the aortic arch. Methods In this study, we report two patients with type B aortic dissection who were complicated with left vertebral artery course variation. Specifically, the left vertebral artery originated from the aortic arch. In these patients, the anchoring area (Result We reconstructed the left vertebral artery during horacic endovascular aortic repair. Both patients recovered well and were discharged without any adverse events. Conclution Our experience shows that horacic endovascular aortic repair is feasible in patients with type B aortic dissection who have an insufficient proximal anchoring area due to the left vertebral artery originating from the aortic arch.
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- 2022
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31. Research on Surface Roughness of Supersonic Vibration Auxiliary Side Milling for Titanium Alloy
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Xianli Liu, DeSheng Hu, caixue yue, XueTao Wei, Yunpeng Ding, and Steven Y. Liang
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Vibration ,Materials science ,Mechanical Engineering ,Surface roughness ,Titanium alloy ,Supersonic speed ,Composite material ,Industrial and Manufacturing Engineering - Abstract
The processed surface contour shape is extracted with the finite element simulation software, and the difference value of contour shape change is used as the parameters of balancing surface roughness to construct the infinitesimal element cutting finite element model of supersonic vibration milling in cutting stability domain. The surface roughness trial scheme is designed in the central composite test design method to analyze the surface roughness test result in the response surface methodology. The surface roughness prediction model is established and optimized. Finally, the finite element simulation model and surface roughness prediction model are verified and analyzed through experiment. The research results show that, compared with the experiment results, the maximum error of finite element simulation model and surface roughness prediction model is 30.9% and12.3%, respectively. So, the model in this paper is accurate and will provide the theoretical basis for optimization study of auxiliary milling process of supersonic vibration.
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- 2021
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32. Effect of Foliar Application of Various Nitrogen Forms on Starch Accumulation and Grain Filling of Wheat (Triticum aestivum L.) Under Drought Stress
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Yunpeng Ding, Xiaoxia Wen, Xiaokang Lv, Wenxin Liang, Xiaoyan Gu, Mei Long, and Yang Liu
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inorganic chemicals ,Starch ,hormone ,antioxidant activity ,chemistry.chemical_element ,Plant Science ,lcsh:Plant culture ,engineering.material ,nitrogen ,chemistry.chemical_compound ,lcsh:SB1-1110 ,Abscisic acid ,Original Research ,water deficit ,biology ,grain weight ,food and beverages ,starch biosynthesis ,Nitrogen ,Horticulture ,Photoassimilate ,Point of delivery ,chemistry ,Catalase ,biology.protein ,engineering ,Fertilizer ,Sink (computing) - Abstract
Foliar nitrogen (N) fertilizer application at later stages of wheat (Triticum aestivum L.) growth is an effective method of attenuating drought stress and improving grain filling. The influences or modes of action of foliar application of various nitrogen forms on wheat growth and grain filling need further research. The objective of this study was to examine the regulatory effects of various forms of foliar nitrogen [NO3–, NH4+, and CO(NH2)2] on wheat grain filling under drought stress and to elucidate their underlying mechanisms. The relative effects of each nitrogen source differed in promoting grain filling. Foliar NH4+-N application notably prolonged the grain filling period. In contrast, foliar application of CO(NH2)2 and NO3–-N accelerated the grain filling rate and regulated levels of abscisic acid (ABA), z-riboside (ZR), and ethylene (ETH) in wheat grains. Analysis of gene expression revealed that CO(NH2)2 and NO3–-N upregulated the genes involved in the sucrose–starch conversion pathway, promoting the remobilization of carbohydrates and starch synthesis in the grains. Besides, activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) were increased, whereas the content of malondialdehyde (MDA) declined under foliar nitrogen application (especially NH4+-N). Under drought stress, enhancement of carbohydrate remobilization and sink strength became key factors in grain filling, and the relative differences in the effects of three N forms became more evident. In conclusion, NH4+-N application improved the antioxidant enzyme system and delayed photoassimilate transportation. On the other hand, foliar applications of NO3–-N and CO(NH2)2 enhanced sink capacity and alleviated drought stress injury in wheat.
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- 2021
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33. Response of soil microbial community parameters to plastic film mulch: A meta-analysis
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Yüze Li, Huanxin Xie, Zhangheng Ren, Yunpeng Ding, Mei Long, Guangxin Zhang, Xiaoliang Qin, Kadambot H.M. Siddique, and Yuncheng Liao
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Soil Science - Published
- 2022
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34. Age assessment by Demirjian’s development stages of the third molar: a systematic review
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Pål Skage Dahlberg, Gyri Synnøve Hval Straumann, Øyvind Bleka, Veslemøy Rolseth, Yunpeng Ding, Gerd Jorunn Møller Delaveris, Gunn Elisabeth Vist, Marianne Skjerven-Martinsen, and Annhild Mosdøl
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Adult ,Male ,Molar ,medicine.medical_specialty ,Adolescent ,Age structure ,media_common.quotation_subject ,030218 nuclear medicine & medical imaging ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Young adult ,Child ,media_common ,Selection bias ,business.industry ,Age Factors ,General Medicine ,Chronological age ,Radiography ,030220 oncology & carcinogenesis ,Healthy individuals ,Assessment methods ,Female ,Molar, Third ,Radiology ,Age Determination by Teeth ,business ,Demography - Abstract
Radiographic evaluation of the wisdom teeth (third molar) formation is a widely used age assessment method for adolescents and young adults. This systematic review examines evidence on the agreement between Demirjian’s development stages of the third molar and chronological age. We searched four databases up until May 2016 for studies reporting Demirjian’s stages of third molar and confirmed chronological age of healthy individuals aged 10–25 years. Heterogeneity test of the included studies was performed. We included 21 studies from all continents except Australia, all published after 2005. The mean chronological age for Demirjian’s stages varied considerably between studies. The results from most studies were affected by age mimicry bias. Only a few of the studies based their results on an unbiased age structure, which we argue as important to provide an adequate description of the method’s ability to estimate age. Observed study variation in the timing of Demirjian’s development stages for third molars has often been interpreted as differences between populations and ethnicities. However, we consider age mimicry to be a dominant bias in these studies. Hence, the scientific evidence is insufficient to conclude whether such differences exist. • There is significant heterogeneity between studies evaluating age assessment by Demirjian’s third molar development. • Most of the studies were subject to the selection bias age mimicry which can be a source of heterogeneity. • Presence of age mimicry bias makes it impossible to compare and combine results. These biased studies should not be applied as reference studies for age assessment.
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- 2018
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35. Role of pre-vertical compression in deformation behavior of Mg alloy AZ31B during super-high reduction hot rolling process
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Weitao Jia, Fangkun Ning, Yunpeng Ding, Jianzhong Cui, Qichi Le, and Yan Tang
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010302 applied physics ,Materials science ,Polymers and Plastics ,Mechanical Engineering ,Metals and Alloys ,Recrystallization (metallurgy) ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Grain size ,Mechanics of Materials ,0103 physical sciences ,Ultimate tensile strength ,Materials Chemistry ,Ceramics and Composites ,Dynamic recrystallization ,Formability ,Texture (crystalline) ,Deformation (engineering) ,Composite material ,0210 nano-technology ,Crystal twinning - Abstract
Mg alloy AZ31B plates were processed by hot rolling with different thickness reductions per pass and pre-vertical compression followed by super-high reduction hot rolling (PVCR), respectively. Microstructure evolution, rolling formability variation and mechanical responses were investigated. As reduction per pass increased, the number of shear bands deflecting toward rolling direction increased, resulting in easy crack initiation in and around the bands. With increasing reduction per pass up to 80%, twinning and twinning-induced dynamic recrystallization (DRX) dominated the deformation of the edge material at 350 °C, resulting in local recrystallization with coarse grains and further largest edge-crack degree. Pre-induced {10 1 ¯ 2} tensile twins by pre-vertical compression (PVC) increased number density of nucleation sites for dynamic recrystallization during the subsequent severe rolling, which enhanced the dominant role of continuous dynamic recrystallization. Designed PVCR-b was proved to be a relatively effective method to improve rolling formability of rolled Mg alloy AZ31B plates. With this method, mean grain size of AZ31B plate was significantly refined from ∼600 mm to ∼14.1 mm and more homogeneous grain size distribution along transverse direction (TD) was achieved. In addition, basal texture intensity was greatly weakened. As a result, tensile anisotropy was distinctly decreased and fracture elongation increased dramatically.
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- 2018
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36. Role of pre-width reduction in deformation behavior of AZ31B alloy during break-down rolling and finish rolling
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Yunpeng Ding, Qichi Le, Yan Tang, Weitao Jia, Fangkun Ning, and Jianzhong Cui
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010302 applied physics ,Materials science ,Mechanical Engineering ,Recrystallization (metallurgy) ,02 engineering and technology ,Edge (geometry) ,Deformation (meteorology) ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Microstructure ,01 natural sciences ,Shear (sheet metal) ,Mechanics of Materials ,0103 physical sciences ,Formability ,General Materials Science ,Texture (crystalline) ,Composite material ,0210 nano-technology ,Crystal twinning - Abstract
Present study aimed at investigating the effect of introducing pre-width reduction (Pre-WR) on microstructure evolution and rolling formability variation during both the break-down rolling and finish rolling of AZ31B alloy. Different rolling routes relevant to the above two rolling processes were performed and compared. Results show that pre-induced twins by pre-rolling (8% thickness reduction) can significantly reduce the edge-cracking depth level during subsequent super-high reduction rolling (SHRR) (80% thickness reduction) through replacing the formation of shear bands by the promotion of the twinning-induced recrystallization to coordinate the severe deformation. However, the dominant behavior of twinning and twinning-induced DRX within the edge region induced a unique partial recrystallization with coarse grains and further a poor rolling formability in SHRR. Introducing more {10 1 ¯ 2} tensile twins at the edge by Inter-WR (a Pre-WR type with 10% width reduction) before the SHRR can significantly refine the grains and obtain almost a recrystallized homogeneous microstructure. It can also weaken the basal texture of the edge material and further decrease the number/depth level of edge crack by enhancing the activity of both non-basal slips and dominant continuous dynamic recrystallization (CDRX). During finish rolling, heavy twins and shear bands resulted in the larger edge crack level. The improvement of Pre-WR on rolling formability can be inherited to the strip finishing rolling process by evidently reducing the twins and shear bands.
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- 2018
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37. Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, 1-year follow-up: a cluster-randomised trial
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Matt Oxman, Margaret Kaseje, Angela Morelli, Andrew D Oxman, Claire Glenton, Atle Fretheim, Allen Nsangi, Nelson K. Sewankambo, Daniel Semakula, Sarah Rosenbaum, Iain Chalmers, Simon Lewin, Astrid Austvoll-Dahlgren, and Yunpeng Ding
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Male ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,education ,Evidence-based healthcare ,Medicine (miscellaneous) ,1 year follow up ,Health literacy ,Disease cluster ,School intervention ,Choice Behavior ,03 medical and health sciences ,0302 clinical medicine ,Intervention (counseling) ,medicine ,Training ,Humans ,Uganda ,Pharmacology (medical) ,030212 general & internal medicine ,Child ,Children ,Health Education ,School Health Services ,lcsh:R5-920 ,business.industry ,Research ,4. Education ,Informed decision-making ,Child Health ,Reproducibility of Results ,Test (assessment) ,Clinical trial ,Public involvement ,Treatment Outcome ,Family medicine ,Female ,lcsh:Medicine (General) ,business ,Critical thinking ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
IntroductionWe evaluated an intervention designed to teach 10- to 12-year-old primary school children to assess claims about the effects of treatments (any action intended to maintain or improve health). We report outcomes measured 1 year after the intervention.MethodsIn this cluster-randomised trial, we included primary schools in the central region of Uganda that taught year 5 children (aged 10 to 12 years). We randomly allocated a representative sample of eligible schools to either an intervention or control group. Intervention schools received the Informed Health Choices primary school resources (textbooks, exercise books and a teachers’ guide). The primary outcomes, measured at the end of the school term and again after 1 year, were the mean score on a test with two multiple-choice questions for each of the 12 concepts and the proportion of children with passing scores.ResultsWe assessed 2960 schools for eligibility; 2029 were eligible, and a random sample of 170 were invited to recruitment meetings. After recruitment meetings, 120 eligible schools consented and were randomly assigned to either the intervention group (n = 60 schools; 76 teachers and 6383 children) or the control group (n = 60 schools; 67 teachers and 4430 children). After 1 year, the mean score in the multiple-choice test for the intervention schools was 68.7% compared with 53.0% for the control schools (adjusted mean difference 16.7%; 95% CI, 13.9 to 19.5;P ConclusionUse of the learning resources led to a large improvement in the ability of children to assess claims, which was sustained for at least 1 year.Trial registrationPan African Clinical Trial Registry (www.pactr.org), PACTR201606001679337. Registered on 13 June 2016.
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- 2020
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38. Geno: A Developer Tool for Authoring Multimodal Interaction on Existing Web Applications
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Xiang 'Anthony' Chen, Yunpeng Ding, Ritam Jyoti Sarmah, Cheuk Yin Phipson Lee, Di Wang, and Toby Jia-Jun Li
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Direct voice input ,FOS: Computer and information sciences ,Modality (human–computer interaction) ,business.industry ,Computer science ,05 social sciences ,Computer Science - Human-Computer Interaction ,020207 software engineering ,Context (language use) ,02 engineering and technology ,Voice command device ,Multimodal interaction ,Human-Computer Interaction (cs.HC) ,Workflow ,Human–computer interaction ,0202 electrical engineering, electronic engineering, information engineering ,Web application ,0501 psychology and cognitive sciences ,Language model ,business ,050107 human factors - Abstract
Supporting voice commands in applications presents significant benefits to users. However, adding such support to existing GUI-based web apps is effort-consuming with a high learning barrier, as shown in our formative study, due to the lack of unified support for creating multimodal interfaces. We present Geno---a developer tool for adding the voice input modality to existing web apps without requiring significant NLP expertise. Geno provides a high-level workflow for developers to specify functionalities to be supported by voice (intents), create language models for detecting intents and the relevant information (parameters) from user utterances, and fulfill the intents by either programmatically invoking the corresponding functions or replaying GUI actions on the web app. Geno further supports multimodal references to GUI context in voice commands (e.g. "move this [event] to next week" while pointing at an event with the cursor). In a study, developers with little NLP expertise were able to add multimodal voice command support for two existing web apps using Geno.
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- 2020
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39. MOESM3 of Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, 1-year follow-up: a cluster-randomised trial
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Nsangi, Allen, Semakula, Daniel, Oxman, Andrew, Austvoll-Dahlgren, Astrid, Oxman, Matt, Rosenbaum, Sarah, Morelli, Angela, Glenton, Claire, Lewin, Simon, Kaseje, Margaret, Chalmers, Iain, Fretheim, Atle, Yunpeng Ding, and Sewankambo, Nelson
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Additional file 3. Distribution of scores and curves.
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- 2020
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40. Effects of the Informed Health Choices primary school intervention on the ability of children in Uganda to assess the reliability of claims about treatment effects, one-year follow-up: a cluster-randomised trial
- Author
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Allen Nsangi, Daniel Semakula, Andrew David Oxman, Astrid Austvoll- Dalghren, Matt Oxman, Sarah Rosenbaum, Angela Morelli, Claire Glenton, Simon Lewin, Margaret Kaseje, Iain Chalmers, Atle Freithem, Kristoffer Yunpeng Ding, and Nelson Kaulukusi Kaulukusi Sewankambo
- Subjects
education - Abstract
Introduction We evaluated an intervention designed to teach 10 to 12-year-old primary school children to assess claims about the effects of treatments (any action intended to maintain or improve health). We report here on outcomes measured one year after the intervention. Methods In this cluster-randomised trial, we included primary schools in the central region of Uganda that taught year-five children (aged 10 to 12 years). We randomly allocated a representative sample of eligible schools to either an intervention or control group. Intervention schools received the Informed Health Choices primary school resources (textbooks, exercise books, and a teachers’ guide). The primary outcome, measured at the end of the school term and again after one year, was the mean score on a test with two multiple-choice questions for each of the 12 concepts and the proportion of children with passing scores. Results We assessed 2960 schools for eligibility; 2029 were eligible, and a random sample of 170 were invited to recruitment meetings. After recruitment meetings, 120 eligible schools consented and were randomly assigned to either the intervention group (n=60, 76 teachers and 6383 children) or control group (n=60, 67 teachers and 4430 children). After one year, the mean score in the multiple-choice test for the intervention schools was 68.7% compared to 53.0% for the control schools (adjusted mean difference 16.7%, 95% CI 13.9 to 19.5; p
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- 2019
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41. Progress in the prevention and control of water-borne arsenicosis in China
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Lin Gao, Wei Zhang, Dianjun Sun, Wei Wei, Lijun Zhao, Zhenbo Yang, Guangqian Yu, Yanhui Gao, Yunpeng Ding, Ji Xiaohong, Wei Wang, and Yuanyuan Li
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China ,Health, Toxicology and Mutagenesis ,Drinking Water ,Public Health, Environmental and Occupational Health ,General Medicine ,Environmental Exposure ,010501 environmental sciences ,01 natural sciences ,Pollution ,Arsenic ,Water Purification ,03 medical and health sciences ,0302 clinical medicine ,Water Supply ,Environmental health ,Arsenic Poisoning ,Prevalence ,Water Pollution, Chemical ,Environmental science ,Humans ,030212 general & internal medicine ,Water Pollutants, Chemical ,0105 earth and related environmental sciences ,Environmental Monitoring - Abstract
In this report, we provided an overview of the prevalence, control, and prevention of water-borne arsenicosis in China during 2001-2016. Random sampling was continuously performed during 2001-2010 to find villages having high levels of arsenic (50 µg/L) in drinking water. The high-arsenic-exposure villages with more geographically dispersed water supplies were subsequently analyzed for characteristics of arsenic distribution, and villages with relatively large populations were investigated for arsenicosis. The results showed that among 32,673,677 inhabitants in 36,820 villages, 1,894,587 inhabitants in 2,476 villages were at risk of high arsenic exposure. Among the 33,318 drinking water sources surveyed in 625 high-arsenic-exposure villages, 9,807 drinking water sources that contained high levels of arsenic (50 µg/L) were identified. The overall prevalence rate of arsenicosis was 1.93%. Further, some representative villages were chosen to monitor arsenicosis annually, showing that the prevalence rate of arsenicosis was lower in villages with arsenic-safe water supplies than in villages without arsenic-safe water supplies. To the best of our knowledge, this report provides the most comprehensive assessment of the distribution of high arsenic exposure and arsenicosis in China until now.
- Published
- 2019
42. [Mid-term effectiveness of arthroscopic anterior cruciate ligament reconstruction combined with meniscus allograft transplantation]
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Yunpeng, Ding, Yadong, Zhang, Haigang, Jia, Dongqiang, Gu, and Lei, Chen
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Adult ,Male ,Adolescent ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,Anterior Cruciate Ligament Injuries ,Middle Aged ,musculoskeletal system ,Allografts ,Arthroscopy ,Young Adult ,Treatment Outcome ,前交叉韧带损伤修复与重建 ,Humans ,Female ,Meniscus ,Anterior Cruciate Ligament ,Retrospective Studies - Abstract
To summarize the mid-term effectiveness of arthroscopic anterior cruciate ligament (ACL) reconstruction combined with meniscus allograft transplantation.A clinical data of 21 patients treated with arthroscopic ACL reconstruction and meniscus allograft transplantation and followed up more than 5 years between February 2007 and December 2014 was retrospectively analyzed. There were 12 males and 9 females, aged from 18 to 45 years, with an average age of 23.5 years. The cause of injury was sport sprain in 15 cases, falling in 4 cases, and traffic accident in 2 cases. The time from injury to operation ranged from 2 to 36 months, with an average of 12 months. Among them, 15 patients underwent previous meniscectomy, with an average interval of 1.6 years (range, 3 months to 6.5 years). All patients were primary ACL reconstruction. Preoperative anterior drawer test, Lachman test, and pivot shift test were positive. Lysholm score was 43.6±10.2. International Knee Documentation Committee (IKDC) score was 60.50±14.06. Of the 21 patients, 10 were gradeⅠ-Ⅱcartilage injuries and 11 were grade Ⅲ cartilage injuries according to MRI.All patients were followed up 5.1-7.8 years, with an average of 5.5 years. There were 2 cases of numbness of lower extremity, 3 cases of slight exudation of incision, 2 cases of articular movement bounce, 5 cases of mild joint swelling and pain after exercise. At last follow-up, Lachman tests were negative in 18 cases and positive in 3 cases; anterior drawer tests were negative in 19 cases and positive in 2 cases; pivot shift tests were negative in all cases. Lysholm score was 84.5±16.5 and IKDC score was 85.25±4.60, which were significantly higher than those before operation (For patients with severe meniscus injury and ACL rupture, ACL reconstruction combined with meniscus allograft transplantation can restore the stability of the joint, recover the meniscus function which is conducive to the protection of articular cartilage and obtain satisfactory mid-term effectiveness.总结关节镜下前交叉韧带(anterior cruciate ligament,ACL)重建联合同种异体半月板移植术治疗半月板严重损伤伴 ACL 断裂的中期疗效。.回顾分析 2007 年 2 月—2014 年 12 月,21 例接受 ACL 重建联合同种异体半月板移植治疗并随访 5 年以上的患者临床资料。男 12 例,女 9 例;年龄 18~45 岁,平均 23.5 岁。致伤原因:运动扭伤 15 例,摔伤 4 例,交通事故伤 2 例。受伤至手术时间为 2~36 个月,平均 12 个月。其中 15 例患者既往行半月板切除术,与该次手术间隔 3 个月~6.5 年,平均 1.6 年。21 例均为初次 ACL 重建。术前前抽屉试验、Lachman 试验、轴移试验均为阳性。Lysholm 评分为(43.6±10.2)分,国际膝关节文献委员会(IKDC)评分为(60.50±14.06)分。术前 MRI 关节软骨分级:Ⅰ~Ⅱ级 10 例,Ⅲ级 11 例。.术后患者均获随访,随访时间 5.1~7.8 年,平均 5.5 年。术后出现下肢麻木 2 例,切口轻度渗液 3 例,关节活动弹响 2 例,运动锻炼后关节轻度肿胀、疼痛 5 例。末次随访时,Lachman 试验阴性 18 例,阳性 3 例;前抽屉试验阴性 19 例,阳性 2 例;轴移试验均为阴性。Lysholm 评分为(84.5±16.5)分,IKDC 评分为(85.25±4.60)分,均明显高于术前(对于半月板严重损伤伴 ACL 断裂患者,同种异体半月板移植联合 ACL 重建能恢复关节稳定性,同时半月板功能的恢复有利于保护关节软骨,中期疗效良好。.
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- 2019
43. Methylenetetrahydrofolate Dehydrogenase 1 Polymorphisms Modify the Associations of Plasma Glycine and Serine With Risk of Acute Myocardial Infarction in Patients With Stable Angina Pectoris in WENBIT (Western Norway B Vitamin Intervention Trial)
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Grethe S. Tell, Eva Ringdal Pedersen, Klaus Meyer, Ottar Nygård, Jesse F. Gregory, Kjetil Halvorsen Løland, Gard Frodahl Tveitevåg Svingen, Yunpeng Ding, Øyvind Helgeland, and Per Magne Ueland
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Male ,0301 basic medicine ,Time Factors ,Myocardial Infarction ,030204 cardiovascular system & hematology ,Coronary Angiography ,Serine ,Coronary artery disease ,0302 clinical medicine ,Gene Frequency ,Risk Factors ,Myocardial infarction ,Genetics (clinical) ,Norway ,Homozygote ,Middle Aged ,Prognosis ,Phenotype ,Biochemistry ,Female ,Cardiology and Cardiovascular Medicine ,Heterozygote ,medicine.medical_specialty ,Glycine ,MTHFD1 ,Risk Assessment ,Minor Histocompatibility Antigens ,03 medical and health sciences ,Internal medicine ,Genetics ,medicine ,Humans ,Genetic Predisposition to Disease ,Angina, Stable ,Aged ,Proportional Hazards Models ,Methylenetetrahydrofolate Dehydrogenase (NADP) ,Polymorphism, Genetic ,business.industry ,Metabolism ,medicine.disease ,B vitamins ,Logistic Models ,030104 developmental biology ,Endocrinology ,Methylenetetrahydrofolate dehydrogenase ,Multivariate Analysis ,Linear Models ,business - Abstract
Background— Serine and glycine interconversion and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)–mediated 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism. Recently, plasma glycine and a common polymorphism in MTHFD1 have been associated with risk of acute myocardial infarction (AMI). It is, therefore, of interest to explore if these 2 pathways interact in relation to AMI. Methods and Results— A total of 2571 participants in the WENBIT (Western Norway B Vitamin Intervention Trial) undergoing coronary angiography for stable angina pectoris were studied. Associations of plasma serine and glycine concentrations with risk of AMI across 2 common and functional MTHFD1 polymorphisms ( rs2236225 and rs1076991 ) were explored in Cox regression models. During a median follow-up of 4.7 years, 212 patients (8.2%) experienced an AMI. In age- and sex-adjusted analyses, plasma glycine ( P P =0.52), showed an overall association with AMI. However, interactions of MTHFD1 rs2236225 polymorphism with both plasma serine and glycine were observed ( P interaction =0.03 for both). Low plasma serine and glycine were associated with an increased risk of AMI among patients carrying the rs2236225 minor A allele. Similarly, low plasma glycine showed stronger risk relationship with AMI in the rs1076991 CC genotype carriers but weaker associations in patients carrying the minor T allele ( P interaction =0.02). Conclusions— Our results showed that 2 common and functional polymorphisms in the MTHFD1 gene modulate the risk associations of plasma serine and glycine with AMI. These findings emphasize the possible role of the MTHFD1 in regulating serine and glycine metabolism in relation to atherosclerotic complications. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique Identifier: NCT00354081.
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- 2016
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44. Off-line error compensation in corner milling process
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Xianli Liu, Steven Y. Liang, Yunpeng Ding, and Cai Xu Yue
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0209 industrial biotechnology ,Engineering ,business.industry ,Mechanical Engineering ,Hardware_PERFORMANCEANDRELIABILITY ,02 engineering and technology ,Structural engineering ,Industrial and Manufacturing Engineering ,020303 mechanical engineering & transports ,020901 industrial engineering & automation ,0203 mechanical engineering ,Deflection (engineering) ,Control theory ,Cutting force ,Effective method ,business ,Off line - Abstract
Tool deflection induced by cutting force could result in dimensional inaccuracies or profile error in corner milling process. Error compensation has been proved to be an effective method to get accuracy component in milling process. This article presents a methodology to compensate profile errors by modifying tool path. The compensation effect strongly depends on accuracy of the cutting force model used. The mathematical expression of chip thickness is proposed based on the true track of cutting edge for corner milling process, which considers the effect of tool deflection. The deflection of tool is calculated by finite element method. Then, an off-line compensation algorithm for corner profile error is developed. Following the theoretical analysis, the effect of the error compensation algorithm is verified by experimental study. The outcome provides useful comprehension about selection of process conditions for corner milling process.
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- 2016
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45. Effect of rolling speed on microstructure and mechanical properties of as-cast AZ31B alloy under different reduction schedules
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Yunpeng Ding, Qichi Le, Zhiqiang Zhang, and Jianzhong Cui
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010302 applied physics ,Materials science ,Metallurgy ,Metals and Alloys ,Recrystallization (metallurgy) ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,Industrial and Manufacturing Engineering ,Grain size ,Computer Science Applications ,Modeling and Simulation ,0103 physical sciences ,Ultimate tensile strength ,Ceramics and Composites ,Dynamic recrystallization ,0210 nano-technology ,Crystal twinning ,AZ31B alloy ,Rolling speed - Abstract
AZ31B alloy was severely rolled at speeds between 18 and 102 m/min by two different reduction schedules, respectively. The recrystallization behaviors, rolling feasibility, temperature distribution, texture and mechanical properties were examined. The {10 1 ¯ 2} tensile twinning and subsequent secondary twinning and continuous dynamic recrystallization dominated the deformation. For 4-pass rolling, as the speed increased, the twin density gradually decreased and the grain size slightly rose due to the suppressed temperature reduction at higher speed. However the effective grain size sharply increased and the recrystallization fraction dropped with increased rolling speed for 2-pass rolling. Full recrystallization mainly occurred in grains with beneficial orientations for {10 1 ¯ 2} twinning, rather than dislocation, during 2-pass rolling at speeds higher than 72 m/min. The rolling feasibility, texture and mechanical properties were largely affected by rolling speed. However, their trends were significantly different, sometimes even on the contrary, under different reduction schedules.
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- 2016
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46. B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris
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Eva Ringdal Pedersen, Gard Frodahl Tveitevåg Svingen, Klaus Meyer, Per Magne Ueland, Åse Fredriksen, Jesse F. Gregory, Ottar Nygård, Stefan Johansson, Yunpeng Ding, and Øyvind Helgeland
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One carbon metabolism ,Male ,0301 basic medicine ,Time Factors ,Endocrinology, Diabetes and Metabolism ,Myocardial Infarction ,Medicine (miscellaneous) ,Kaplan-Meier Estimate ,030204 cardiovascular system & hematology ,medicine.disease_cause ,Gastroenterology ,0302 clinical medicine ,Risk Factors ,Myocardial infarction ,Nutrition and Dietetics ,Norway ,MTHFD1 ,Middle Aged ,B vitamin ,Phenotype ,Treatment Outcome ,Vitamin B Complex ,Female ,Risk assessment ,Cardiology and Cardiovascular Medicine ,medicine.medical_specialty ,Placebo ,Risk Assessment ,Minor Histocompatibility Antigens ,03 medical and health sciences ,Folic Acid ,Internal medicine ,medicine ,Humans ,Genetic Predisposition to Disease ,Angina, Stable ,Aged ,Methylenetetrahydrofolate Dehydrogenase (NADP) ,Polymorphism, Genetic ,business.industry ,Lipid metabolism ,medicine.disease ,Vitamin B 6 ,Surgery ,B vitamins ,030104 developmental biology ,Methylenetetrahydrofolate dehydrogenase ,business ,Oxidative stress - Abstract
Background: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Impaired MTHFD1 flux has been linked to disturbed lipid metabolism and oxidative stress. However, limited information is available on its relation to the development of atherothrombotic cardiovascular disease. Methods and results: We explored the association between a MTHFD1 polymorphism (rs1076991 C > T ) and acute myocardial infarction (AMI), and potential effect modifications by folic acid/B12 and/or vitamin B6 treatment in suspected stable angina pectoris patients (n Z 2381) participating in the randomized Western Norway B Vitamin Intervention Trial (WENBIT). During the median follow-up of 4.9 years 204 participants (8.6%) suffered an AMI. After adjusting for established CVD risk factors, the MTHFD1 polymorphism was significantly associated with AMI (HR: 1.49; 95% CI, 1.23e1.81). A similar association was observed among patients allocated to treatment with vitamin B6 alone (HR: 1.53; 95% CI, 1.01e2.31), and an even stronger relationship was seen in patients treated with both vitamin B6 and folic acid/B12 (HR: 2.35; 95% CI, 1.55 e3.57). However, no risk association between the MTHFD1 polymorphism and AMI was seen in patients treated with placebo (HR: 1.29; 95% CI, 0.86e1.93) or folic acid/B12 (1.17; 95% CI, 0.83e1.65). Conclusion: A common and functional MTHFD1 polymorphism is associated with increased risk of AMI, although the risk seems to be dependent on specific B vitamin treatment. Further studies are warranted to elucidate the possible mechanisms, also in order to explore potential effect modifications by nutritional factors. publishedVersion
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- 2016
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47. On-line tool wear monitoring based on machine learning
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Zhengyan Bai, Liu Qiang, Xianli Liu, Steven Y. Liang, Caixu Yue, Yunpeng Ding, and Dianfang Mu
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Network packet ,Computer science ,business.industry ,SIGNAL (programming language) ,Machine learning ,computer.software_genre ,Domain (software engineering) ,Wavelet ,Milling cutter ,Line (geometry) ,Artificial intelligence ,State (computer science) ,Tool wear ,business ,computer - Abstract
Accurate tool condition monitoring is necessary for the development of automatic milling technology. In order to improve the accuracy and real-time of online monitoring of tool wear state in machining process, an online monitoring system of milling cutter state based on LabVIEW software development is proposed. Firstly, the modern monitoring technology is introduced into the online monitoring of tool state in principle. The vibration signal is analyzed by wavelet packet in time-frequency domain, and the online monitoring of tool state is realized by machine learning algorithm model. The system can be used for real-time monitoring of tool status, timely alarm to facilitate tool replacement, and ensure high efficiency and high quality of processing. The effectiveness and feasibility of the online monitoring system for milling cutter wear state are verified by experiments, and the purpose of online monitoring tool wear state is preliminarily realized.
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- 2021
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48. Identification of Friction Parameters of Robot Joints Based on Energy Consumption Model
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Xiangxiu Meng, Ningbo Lv, Yunpeng Ding, and Xuejun Zhu
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History ,Identification (information) ,Computer science ,Control theory ,Robot ,Energy consumption ,Computer Science Applications ,Education - Abstract
In order to solve the problem that the joint friction torque value of industrial robots is difficult to be measured in practice, the joint friction identification method based on the energy model is used to indirectly obtain the friction model parameters by measuring the energy consumption value. According to the energy model and the measured robot energy value, the genetic algorithm is used to realize the parameter identification of the Stribeck friction model of joint friction. The results of the two identification methods based on friction torque identification and energy model identification are compared. The simulation results show that the error ratio of all the friction model parameters obtained by the two identification methods is less than 8%, and the error target value of the two identification results is less than 0.1%, which can effectively identify the relevant friction parameters. By designing an experimental scheme, the different speeds and corresponding energy consumption data of the IRB140 robot when joint 1 operates at a constant speed in a specified time are measured, and the Stribeck friction model parameters of the IRB140 robot’s joint 1 are identified by the proposed method.
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- 2020
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49. Soft Sensor Simulation of Minimum Energy Consumption of Joint Manipulator Drive System Based on Improved BP Neural Network
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Xuejun Zhu, Yunpeng Ding, Xuqiang Sun, Ji Zhang, and Xu Chen
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History ,Artificial neural network ,Computer science ,Control theory ,Energy consumption ,Manipulator ,Soft sensor ,Joint (geology) ,Computer Science Applications ,Education - Abstract
The energy dissipation level of articulated mechanical arms directly affects the control stability of industrial robot systems. For a six-degree-of-freedom articulated robot driven by a DC servo motor and reduction gear, based on the Hamiltonian and Minimum theories, a model of the articulated manipulator drive system under load torque is established, and the expressions of optimal angular velocity and control current are obtained considering the viscous friction and coulomb factors. According to the analysis of actual parameter simulation experiments, it can be seen that the energy consumption of the joint manipulator drive system increases with the decrease of efficiency, the increase of the coulomb friction torque of the servo motor, and the increase of the load torque. Within the transit time, the total energy consumption of the drive system is smaller, so it is very important to obtain the transit time within the optimal area for the minimum energy consumption of the joint robotic arm drive system. At the same time, a soft neural network model based on the improved BP neural network built on the neural network toolbox for the energy consumption of the articulated mechanical arm is established. Finally, the experimental platform of servo motor drive system is built and used for the experiment of servo motor drive, and the purpose of closed-loop control is also achieved. Through experimental analysis, it can be seen that the proposed soft sensor model of joint minimum energy consumption based on improved BP neural network can more accurately realize the energy consumption prediction under unknown angular displacement and unknown load, and provide a theoretical basis for joint energy monitoring.
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- 2020
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50. Arthroscopic techniques and instruments for meniscal allograft transplantation using the bone bridge in trough method
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Hong-Bin Zhong, Dongqiang Gu, Shuxun Hou, Yichao Zhang, Li Li, Haigang Jia, Lei Chen, Yunpeng Ding, Yadong Zhang, and Dian‑Zhong Luo
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Cancer Research ,medicine.medical_treatment ,surgical instrument ,menisci ,03 medical and health sciences ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,Joint capsule ,medicine ,Tibia ,minimally invasive surgery ,arthroscopy ,Orthodontics ,030222 orthopedics ,medicine.diagnostic_test ,business.industry ,meniscal allograft transplantation ,Arthroscopy ,Articles ,030229 sport sciences ,General Medicine ,Traction (orthopedics) ,musculoskeletal system ,Transplantation ,medicine.anatomical_structure ,Coronary ligament ,Surgical instrument ,Bone bridge ,business - Abstract
The aim of the current study was to investigate the construction of the bone bridge and tibial plateau under arthroscopy during meniscal allograft transplantation, in order to simplify and enhance the accuracy of bone bridge fixation intraoperatively. A traction line passed through the attachment of the anterior and posterior horns of the superior meniscus to the bone bridge was used to pull the bone bridge into the knee joint cavity and fix the anteroposterior horns of the meniscus. At the junction of the body of the meniscus and the posterior and anterior horns of the meniscus, a traction line was created at the anterior and posterior 1/3 of the meniscus to pull and fix the meniscus. Under the arthroscope, the aiming device was placed on the tibial plateau. The direction and width of the guide plate were identical to those of the bone trough of the tibial plateau. The bone tunnel was made using the guide needle and a 9-mm hollow drill, the piston rod was inserted, and the arch-shaped bone knife was inserted along with the piston rod to construct the 9-mm bone trough of the tibial plateau. The periphery of the meniscus was sutured to the joint capsule. These surgical techniques and instruments could standardize meniscal graft transplantation and avoid the incidence of surgical errors caused by mismatched size and shape of the bone bridge and bone trough. This would make the surgery more convenient, safe and accurate. The four-point fixation of the tibial plateau contributed to preventing the reversal of the meniscus during transplantation, and partially reconstructed the coronary ligament of the meniscal tibia, which probably enhanced the stability of the meniscus and minimized the risk of extrusion of the meniscal allograft. The bone bridge and bone trough of the tibial plateau were properly constructed under arthroscopy. Dynamic monitoring of surgical indications, explicit preoperative preparation and standardized surgical procedures could achieve high efficacy and excellent fixation effect during meniscal graft transplantation. The four-point fixation of the tibial plateau maintains and enhances the stability of the meniscal allograft, reduces the risk of meniscal extrusion and ensures the postoperative recovery of meniscal function.
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- 2018
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