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Resumo Fundamento Muitos estudos clínicos confirmaram que a legumain está intimamente relacionada à aterosclerose. Infelizmente, chegaram-se a conclusões diferentes e ainda faltam análises e estudos sobre as características da placa aterosclerótica em pacientes com níveis plasmáticos aumentados de legumain. Objetivos Este estudo teve como objetivo investigar a correlação entre as características da legumain e da placa aterosclerótica coronariana. Métodos Um total de 81 pacientes com doença cardíaca aterosclerótica coronariana (DCAC), incluindo 43 pacientes com angina instável (AI) e 38 pacientes com angina estável (AE), foram examinados por angiografia coronária. Foi realizado ultrassom intravascular (IVUS) para avaliar as características das placas ateroscleróticas coronarianas, e os níveis plasmáticos de legumain também foram medidos. Valores de p < 0,05 foram considerados significativos. Resultados A concentração de legumain foi significativamente maior nos dois subgrupos de doença coronariana do que no grupo controle (todos p

Aerobic irrigation can effectively improve the oxygen environment in the root zone, and enhance crop quality and yield. However, how aerobic irrigation regulates root growth has not been elucidated. In this study, tomato plants were irrigated with three levels of oxygen (high, medium, and low) under underground drip irrigation. The morphology, activity, transcriptome, and hormone content of tomato roots under oxygen irrigation were analyzed. We found that the aeration irrigation significantly promoted root development. Notably, in the high-aeration irrigation treatment (HAI), the total root length, total surface area, total volume, and root activity were 12.41%, 43.2%, 79.1%, and 24.15% higher than in the non-aeration irrigation treatment (CK), respectively. The transcriptome of tomato roots under aeration irrigation was determined with a total of 272 differentially expressed genes (DEGs), including 131 up-regulated and 141 down-regulated genes. The Kyoto encyclopedia of genes and genomes (KEGG) analysis revealed that the DEGs were enriched mainly in the metabolic pathways and plant hormone signal transduction. Among the plant hormone signal transduction, 50% of DEGs belonged to IAA signal-related genes and were upregulated. LC-MS analysis showed that the content of auxin hormones in the tomato roots subjected to aeration irrigation was significantly higher than that in CK. The content of Indole-3-acetic acid (IAA), Indole-3-carboxylic acid (ICA) and Indole-3-carboxaldehyde (ICAld) were 2.3, 2.14 and 1.45 times higher than those of the CK, but insignificant effects were exerted on the contents of cytokinins, salicylic acid, jasmonic acid, abscisic acid, and ethylene. Meanwhile, the key enzyme of auxin synthesis flavin monooxygenase (YUCCA) was significantly up-regulated. The aforementioned results show that aeration irrigation may promote the growth and development of roots by auxin regulation.

This paper presents technology for the suppression of the mechanical coupling errors for an improved decoupled dual-mass micro-gyroscope (DDMG). The improved micro-gyroscope structure decreases the moment arm of the drive decoupled torque, which benefits the suppression of the non-ideal decoupled error. Quadrature correction electrodes are added to eliminate the residual quadrature error. The structure principle and the quadrature error suppression means of the DDMG are described in detail. ANSYS software is used to simulate the micro-gyroscope structure to verify the mechanical coupling error suppression effect. Compared with the former structure, simulation results demonstrate that the rotational displacements of the sense frame in the improved structure are substantially suppressed in the drive mode. The improved DDMG structure chip is fabricated by the deep dry silicon on glass (DDSOG) process. The feedback control circuits with quadrature control loops are designed to suppress the residual mechanical coupling error. Finally, the system performance of the DDMG prototype is tested. Compared with the former DDMG, the quadrature error in the improved dual-mass micro-gyroscope is decreased 9.66-fold, and the offset error is decreased 6.36-fold. Compared with the open loop sense, the feedback control circuits with quadrature control loop decrease the bias drift by 20.59-fold and the scale factor non-linearity by 2.81-fold in the ±400°/s range.

Underground coal gasification (UCG) is a promising option for the recovery of low-rank and inaccessible coal resources. Detailed mineralogical information is essential to understand underground reaction conditions far from the surface and optimize the operation parameters during the UCG process. It is also significant in identifying the environmental effects of UCG residue. In this paper, with regard to the underground gasification of lignite, UCG slag was prepared through simulation tests of oxygen-enriched gasification under different atmospheric conditions, and the minerals were identified by X-Ray diffraction (XRD) and a scanning electron microscope coupled to an energy-dispersive spectrometer (SEM-EDS). Thermodynamic calculations performed using FactSage 6.4 were used to help to understand the transformation of minerals. The results indicate that an increased oxygen concentration is beneficial to the reformation of mineral crystal after ash fusion and the resulting crystal structures of minerals also tend to be more orderly. The dominant minerals in 60%-O2 and 80%-O2 UCG slag include anorthite, pyroxene, and gehlenite, while amorphous substances almost disappear. In addition, with increasing oxygen content, mullite might react with the calcium oxide existed in the slag to generate anorthite, which could then serve as a calcium source for the formation of gehlenite. In 80%-O2 UCG slag, the iron-bearing mineral is transformed from sekaninaite to pyroxene.