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In the current study, silver nanoparticles (AgNPs) were bio-fabricated with the help of aqueous silver nitrate and green apple (Malus Domestica) extract as a precursor and reducing agent, respectiv...

Amiodarone is the first choice for the treatment of arrhythmia, but it is easy to cause extravasation during infusion, after extravasation, it often cause skin injury. The healing of skin injury induced by amiodarone is an inflammatory process. Chrysin, a natural flavonoid, has been investigated to have anti-inflammatory and antioxidant effects. It was reported that chrysin can promote wound healing. So this study aims to investigate the effect of chrysin on amiodarone extravasation-induced skin injury model in rats.The rat model of skin extravasation injury was established by subcutaneous injection of 0.5 mL of amiodarone. After successful modeling, the rats were randomly assigned to the five groups: control group, 10% DMSO group, and low-dose, medium-dose, and high-dose chrysin groups (10, 20 and 40 mg/mL). The extravasation injury model was given locally on the same day for seven days. On day 0, 3, 7 and 10 of administration, the lesion's image were taken to calculate the area, and the tissue of the lesion were collected for HE staining. Then, the level of IL-6 and TNF-α were measured by ELISA, and the protein expression level of bFGF in the wound tissue were detected by immunohistochemical staining.It was found that chrysin groups (20 and 40 mg/mL) compared to contronl group and 10% DMSO solvent group significantly decreased area injury, IL-6 and TNF-α(P 0.05) on day 3, 7, 10. On the other hand, the chrysin group (40 mg/mL) compared to contronl group and 10% DMSO group significantly increase bFGF(P 0.05) on day 3, 7.Chrysin were effective in reducing injury area, reducing inflammation, and promoting the secretion of bFGF, it can promote the healing of skin injury induced by amiodarone extravasation in rats. These findings provide a good theoretical and experimental basis for the prevention and treatment of amiodarone extravasation-induced skin injury, and provide evidence for finding potential healing agents for the prevention and treatment of amiodarone and other corrosive extravasation-induced injuries from the molecular and cytological levels, thus solving the clinical problems.

This paper applies corpus linguistics techniques to study unique words in Hawks’ translation of Hong Lou Meng in comparison with Yang Xianyi’s translation of it. Concordance and Concapp are used to elicit data from Hong Lou Meng. By analyzing three representative unique words “dark-red”, “penny”, “mile”, which belongs to color terms, unit of money, unit of distance respectively, this paper attempts to examine translator’s style based on the study of unique words.

The Chinese economy has since 2003 maintained a level of growth exceeding 10%, with a continuously increasing rate of growth. In terms of the annual economic growth rate cycle, economic activity has remained in the ascendant stage of the economic cycle since 2000. Will the Chinese economy overheat in 2007 or 2008? When will the current economic cycle reach its turning point? Will the increase in CPI develop into severe inflation? These issues have once again become the centre of attention. This chapter has used dynamic monitoring of major economic indices and the leading, coincident, and lagging indices established as part of the Macroeconomic Climate Analytic System to analyse the current economic climate and price situation from various perspectives. It also uses several econometric models to forecast economic development trends and major macroeconomic indices for 2007 and 2008 and suggest certain policy advice. Keywords: Chinese economy; CPI; econometric models; economic climate; economic cycle; Macroeconomic Climate Analytic System; price situation