1. Antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium from a Jeju water concentrate
- Author
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Ji-Hyun Yun, Goo-Hee Choi, Ok-Hwan Lee, Ju-Hyun Cho, Yun-Hee Seo, Jin-Ha Lee, Jung-Hyon Kim, In-Jae Park, and Sung-Hwan Park
- Subjects
0106 biological sciences ,biology ,Dose ,Triglyceride ,Cholesterol ,Brassica ,Blood sugar ,Vanadium ,chemistry.chemical_element ,04 agricultural and veterinary sciences ,biology.organism_classification ,040401 food science ,01 natural sciences ,Applied Microbiology and Biotechnology ,Db/db Mouse ,chemistry.chemical_compound ,0404 agricultural biotechnology ,chemistry ,010608 biotechnology ,Food science ,Glycated hemoglobin ,Food Science ,Biotechnology - Abstract
The purpose of this study was to determine the antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium (BECV). The BECV was prepared following nutriculture of B. napus with a Jeju water vanadium concentrate for 7 day. The BECV was administered to db/db mice for 8 weeks at different dosages (0.028, 0.14, and 0.7 μg/kg; as vanadium concentration in BECV). After 8 weeks, the BECV results showed mouse blood glucose concentrations to significantly decrease, in a dose-dependent manner, compared with the results for control mice. In addition, the concentrations of triglyceride, total cholesterol, and glycated hemoglobin were significantly lower after 8 weeks of administration of 0.7 μg/kg BECV. Therefore, the BECV may have protective effects against type 2 diabetes.
- Published
- 2018