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2 results on '"Yumna Saghir"'

1. Contributors

Author

Shah Rukh Abbas, Ayesha Aftab, Shanzay Ahmed, Hakima Amri, Syeda Marriam Bakhtiar, Iqra Bashir, Attya Bhatti, Alessandro Buriani, Hina Aslam Butt, Maria Carrara, Kamaljyoti Chakravorty, Yong Chen, Colin M. Court, Dipali Dhawan, Benjamin DiPardo, Shailendra Dwivedi, Syeda Maham Fayyaz, Stefano Fortinguerra, Li-Wu Fu, Daniela Gabbia, Muhammad Uzair Hashmi, Yusuf Izci, Peter John, Anu Kalia, Rohit Kambale, Satoru Kaneko, Rajaretinam Rajesh Kannan, Raman Preet Kaur, Muhammad Qasim Khan, Sobia Khurshid, Shao-Bo Liang, Malavika Lingeswaran, Abhilash Ludhiadch, Radhieka Misra, Sanjeev Misra, Anum Munir, Anjana Munshi, Raveendran Muthurajan, Mohammad Nadeem, Sinem Nalbantoglu, Puneet Pareek, Purvi Purohit, Hajra Qayyum, Hifzur Rahman, Yumna Saghir, Praveen Sharma, Sat Pal Sharma, Shonan Sho, Mohammed Haris Siddiqui, Naveed Iqbal Soomro, Saeed Iqbal Soomro, Vincenzo Sorrenti, Thanga Suja Srinivasan, Nida Ali Syed, Huma Syed, Kiyoshi Takamatsu, Dibyendu Talukdar, James S. Tomlinson, Jeewan Ram Vishnoi, and Paul Winograd

Published
2019

2. Single-Cell Omics in CVDs

Author

Mohammad Nadeem, Yumna Saghir, Iqra Bashir, Sobia Khurshid, Saeed Iqbal Soomro, Syeda Marriam Bakhtiar, Anum Munir, Muhammad Qasim Khan, Hina Aslam Butt, Hajra Qayyum, Syeda Maham Fayyaz, Naveed Iqbal Soomro, and Ayesha Aftab

Subjects
Candidate gene, Computational biology, Disease, Biology, Omics
Abstract

This chapter highlights the role of single-cell omics in cardiovascular diseases (CVDs). It starts by highlighting CVDs as a major issue worldwide, covering their genetics and the inheritance pattern that differs from disease to disease. It then explains the two basic techniques, association studies and linkage analysis, used to determine candidate genes, reported to play an important role in the development of CVDs. It then discusses the complex genotype–phenotype correlation that is the outcome of different environmental factors playing a crucial role in disease development. It also explains techniques for single-cell analysis (SCA), which has great prospects to work miracles in the domain of CVDs. The chapter also highlights cardiometabolic phenotype analysis. By the end of the chapter, the utility of single-cell omics in special reference to CVDs has been discussed along with the challenges posed to this emerging method.

Published
2019

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