80 results on '"Yumeng Xu"'
Search Results
2. PycWB: A user-friendly, Modular, and python-based framework for gravitational wave unmodelled search
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Yumeng Xu, Shubhanshu Tiwari, and Marco Drago
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Gravitational waves ,Burst search ,Computer software ,QA76.75-76.765 - Abstract
Unmodelled searches and reconstruction is a critical aspect of gravitational wave data analysis, requiring sophisticated software tools for robust data analysis. This paper introduces PycWB, a user-friendly and modular Python-based framework developed to enhance such analyses based on the widely used unmodelled search and reconstruction algorithm Coherent Wave Burst (cWB). The main features include a transition from C++ scripts to YAML format for user-defined parameters, improved modularity, and a shift from complex class-encapsulated algorithms to compartmentalized modules. The PycWB architecture facilitates efficient dependency management, better error-checking, and the use of parallel computation for performance enhancement. Moreover, the use of Python harnesses its rich library of packages, facilitating post-production analysis and visualization. The PycWB framework is designed to improve the user experience and accelerate the development of unmodelled gravitational wave analysis.
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- 2024
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3. Performance and mechanism of Carrousel oxidation ditch and water Spinach wetland combined process in treating water hyacinth (Pontederia crassipes) biogas slurry
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Yaqin Yu, Xueyou Fang, Lanying Li, and Yumeng Xu
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pontederia crassipes ,biogas slurry ,carrousel oxidation ditch ,water spinach wetland ,refractory organics ,Environmental protection ,TD169-171.8 - Abstract
Owing to its high concentrations of nitrogen and phosphorus, the slurry from water hyacinth (Pontederia crassipes) biogas production cannot be discharged directly without further treatment. To achieve the target of water recycling, a new strategy of combining a Carrousel oxidation ditch with a water spinach wetland was developed in this study for the harmless treatment of Pontederia crassipes biogas slurry. First, the water quality characteristics of the biogas slurry were measured. Then, comprehensive tests of the combined slurry treatment system were carried out to verify pollutant removal performance and mechanism. The results showed that the Carrousel oxidation ditch reduced the inlet pollutant load of the subsequent water spinach wetland. The chemical oxygen demand (COD), and ammonium nitrogen (NH4+-N), total nitrogen (TN), and total phosphorus (TP) contents of the average effluent from the combined system were less than 50 mg/L, 1.6 mg/L, 6 mg/L, and 0.5 mg/L, respectively, which means that all met urban sewage treatment standard of Level 1 Grade A (GB18918-2002). Gas chromatography – mass spectrometry analysis showed that the combined system had decreased various types of organic pollutants in the biogas slurry exponentially, efficiently removing alkane pollutants, aromatic hydrocarbons, and heterocyclic compounds. Scanning electron microscopy images revealed very large surface area of the water spinach roots in the wetland, which played important roles in enriching the microorganisms and trapping organic matter. Plant absorption, microbial degradation, and filtration were the primary ways in which the water spinach wetland purified the biogas slurry.
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- 2023
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4. Non-coding RNAs’ function in cancer development, diagnosis and therapy
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XinYi Zhang, Xiaoqing Xu, Jiajia Song, Yumeng Xu, Hui Qian, Jianhua Jin, and Zhao feng Liang
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Non-coding RNA ,Function ,Cancer ,Development ,Diagnosis ,Therapy ,Therapeutics. Pharmacology ,RM1-950 - Abstract
While previous research on cancer biology has focused on genes that code for proteins, in recent years it has been discovered that non-coding RNAs (ncRNAs)play key regulatory roles in cell biological functions. NcRNAs account for more than 95% of human transcripts and are an important entry point for the study of the mechanism of cancer development. An increasing number of studies have demonstrated that ncRNAs can act as tumor suppressor genes or oncogenes to regulate tumor development at the epigenetic level, transcriptional level, as well as post-transcriptional level. Because of the importance of ncRNAs in cancer, most clinical trials have focused on ncRNAs to explore whether ncRNAs can be used as new biomarkers or therapies. In this review, we focus on recent studies of ncRNAs including microRNAs (miRNAs), long ncRNAs (lncRNAs), circle RNAs (circRNAs), PIWI interacting RNAs (piRNAs), and tRNA in different types of cancer and explore the application of these ncRNAs in the development of cancer and the identification of relevant therapeutic targets and tumor biomarkers. Graphical abstract drawn by Fidraw.
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- 2023
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5. Chelating resin encapsulation for reduced Pb leakage in perovskite solar cells
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Qingrui Wang, Zhenhua Lin, Yumeng Xu, Boyao Zhang, Xing Guo, Zhaosheng Hu, Yue Hao, and Jingjing Chang
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chelating resins ,device encapsulation ,Pb leakage ,perovskite solar cell ,Renewable energy sources ,TJ807-830 ,Environmental sciences ,GE1-350 - Abstract
Abstract Although perovskite solar cells have achieved efficiency over 25%, the toxic of Pb content remains severe problem given its commercial prospect. Especially when the devices suffer harsh weather, the Pb content can easily leak out to soil and water. Chelating resins (CRs) exhibit excellent superiority in treating waste water in industrial field, since the functional groups in CRs can adsorb divalent metal ion to soften and purify waste water. Herein, an iminodiacetic acid (IDA)‐CR is introduced as encapsulation over perovskite solar cells for the first time. The IDA‐CR exhibits high surface area and excellent adsorption capability. Qualitative and quantitative analysis of Pb leakage are studied, and the devices with encapsulation of IDA‐CR can detain over 90% of Pb compared with control devices without encapsulation after immersed in deionized water for 12 h even in acid situation or after heating. This IDA‐CR method provides a new strategy towards environmental and biological‐friendly perovskite optoelectronic devices.
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- 2023
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6. Waste into treasure: New insight to inhibit scale generation in industrial circulating cooling water
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Yumeng Xu, Kunyu Chen, Chenlu Yan, Ping Li, Heliang Pang, and Jinsuo Lu
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Ginkgo fallen leaves ,Alkalinity ,Ca2+ concentration ,Ascorbic acid ,Green development ,Technology - Abstract
The present study investigated the inhibitory role of ginkgo fallen leaves on scale generation in industrial circulating cooling water (ICCW), and the dual scale inhibition mechanism was revealed to demonstrate the ICCW engineering application potential of ginkgo fallen leaves treatment. The results showed that pH, alkalinity and turbidity decreased from 8.68, 295.74 mg/L and 2.482 NTU to 7.27, 111.23 mg/L and 0.483 NTU, respectively, after adding 7.5 g/L fallen leaves in 2 h. The ascorbic acid released by the fallen leaves not only decreased the ICCW alkalinity, but also complexed with the residual Ca2+ to form calcium ascorbate, which combined to inhibit the ICCW scale generation. Finally, compared to other chemical scale inhibition methods, fallen leaves treatment could save 0.34–850 CNY/ton in agent costs. Also, no additional building area was required, saving infrastructure costs. Therefore, turning fallen leaves waste into treasure provided the green and sustainable innovative strategy for scale inhibition in the ICCW, and has significant potential for engineering applications.
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- 2023
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7. The effect of phytochemicals in N-methyl-N-nitro-N-nitroguanidine promoting the occurrence and development of gastric cancer
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Ling Lu, Bei Chen, XinYi Zhang, Yumeng Xu, Longtao Jin, Hui Qian, and Zhao feng Liang
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gastric cancer ,phytochemicals ,prevention ,MNNG ,mechanisms ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Gastric cancer is a common malignant tumor of the digestive tract, with a low early diagnosis rate. N-methyl-N-nitro-N-nitroguanidine (MNNG) is one of the main risk factors for gastric cancer. Phytochemicals are healthy active substances derived from vegetables, fruits, nuts, tea, herbal medicines and other plants. Taking phytochemicals is a very promising strategy for the prevention and treatment of gastric cancer. Many studies have proved that phytochemicals have protective effects on MNNG induced gastric cancer via inhibiting cell proliferation, enhancing immunity, suppressing cell invasion and migration, inducing apoptosis and autophagy, blocking angiogenesis, inhibiting Helicobacter pylori infection as well as regulating metabolism and microbiota. The intervention and therapeutic effects of phytochemicals in MNNG induced gastric cancer have attracted more and more attention. In order to better study and explore the role, advantages and challenges of phytochemicals in MNNG induced gastric cancer, we summarized the intervention and therapeutic effects of phytochemicals in MNNG induced gastric cancer. This review may help to further promote the research and clinical application of phytochemicals in MNNG induced gastric cancer, and provide some new insights.
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- 2023
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8. Understanding the relative contributions of fungi and bacteria led nitrous oxide emissions in an acidic soil amended with industrial waste
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Junhui Yin, Wenjing Cui, Yumeng Xu, Yan Ma, Huaihai Chen, Jingheng Guo, Rui Liu, and Qing Chen
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Fungi ,Nitrous oxides ,Alkaline industrial waste ,Acidic soil ,Extracellular enzyme activity ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Amendment of fertilized arable soil with alkaline industrial waste has the potential to ameliorate soil acidification whilst also improving crop yield. Another co-benefit is nitrous oxide (N2O) emission abatement but the contribution of fungi and bacteria involved in this process remains unclear. Two incubation experiments were conducted to: 1) examine how amendment of acidic soils with a mixture of phosphorus tailings mixture and insoluble potassium-containing rocks (PT) affect N2O emissions and 2) understand the microbial mechanisms and relative contributions of fungi and bacteria responsible for N2O emissions. In the first incubation experiment, the four treatments consisted of: i) the study control, ii) urea, iii) PT amendment and iv) PT amendment plus urea. Results showed that the PT amendment significantly increased soil pH from 4.8 to above 6.0, and reduced N2O emissions by 65.7%. PT-amended soils had higher N2 emissions and faster O2 consumption. The PT amendment significantly increased extracellular enzyme activities of leucine aminopeptidase and N-Acetyl-β-glucosaminidase, while it significantly decreased activities of β-1, 4-glucosidase and β-cellobiosidase. Two antibiotics (cycloheximide and streptomycin) combined with substrate-induced respiration method were used in the second incubation experiment. Compared to soil with urea, urea with PT amendment raised soil bacteria-related N2O from 9.2% to 18.8% while decreasing fungi-related N2O from 50.5% to 43.2%. These findings suggest that the N2O emissions from acidic soils can be considerably mitigated by the application of alkaline industrial wastes. The contribution of fungi should be considered when designing and applying N2O mitigation strategies in acidic soils. Data Availability: Data will be made available on request.
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- 2023
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9. Recent Progress of Electrode Materials for Flexible Perovskite Solar Cells
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Yumeng Xu, Zhenhua Lin, Wei Wei, Yue Hao, Shengzhong Liu, Jianyong Ouyang, and Jingjing Chang
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Flexible electrode ,Flexible perovskite solar cell ,Carbon nanomaterials ,Metallic nanostructures ,Conductive oxide ,Technology - Abstract
Abstract Flexible perovskite solar cells (FPSCs) have attracted enormous interest in wearable and portable electronics due to their high power-per-weight and low cost. Flexible and efficient perovskite solar cells require the development of flexible electrodes compatible with the optoelectronic properties of perovskite. In this review, the recent progress of flexible electrodes used in FPSCs is comprehensively reviewed. The major features of flexible transparent electrodes, including transparent conductive oxides, conductive polymer, carbon nanomaterials and nanostructured metallic materials are systematically compared. And the corresponding modification strategies and device performance are summarized. Moreover, flexible opaque electrodes including metal films, opaque carbon materials and metal foils are critically assessed. Finally, the development directions and difficulties of flexible electrodes are given.
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- 2022
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10. Anticancer applications of phytochemicals in gastric cancer: Effects and molecular mechanism
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Zhaofeng Liang, Yumeng Xu, Yue Zhang, Xinyi Zhang, Jiajia Song, Hui Qian, and Jianhua Jin
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gastric cancer ,phytochemicals ,prevention ,treatment ,mechanisms ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Gastric cancer (GC) is the fourth most common malignant cancer and is a life-threatening disease worldwide. Phytochemicals have been shown to be a rational, safe, non-toxic, and very promising approach to the prevention and treatment of cancer. It has been found that phytochemicals have protective effects against GC through inhibiting cell proliferation, inducing apoptosis and autophagy, suppressing cell invasion and migration, anti-angiogenesis, inhibit Helicobacter pylori infection, regulating the microenvironment. In recent years, the role of phytochemicals in the occurrence, development, drug resistance and prognosis of GC has attracted more and more attention. In order to better understand the relationship between phytochemicals and gastric cancer, we briefly summarize the roles and functions of phytochemicals in GC tumorigenesis, development and prognosis. This review will probably help guide the public to prevent the occurrence and development of GC through phytochemicals, and develop functional foods or drugs for the prevention and treatment of gastric cancer.
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- 2023
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11. Role of ferroptosis and ferroptosis-related non-coding RNAs in the occurrence and development of gastric cancer
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Ling Lu, Bei Chen, Yumeng Xu, Xinyi Zhang, Longtao Jin, Hui Qian, Yi Wang, and Zhao Feng Liang
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gastric cancer ,ferroptosis ,noncoding RNA ,mechanisms ,function ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Gastric cancer (GC) is a malignant cancer of the digestive tract and is a life-threatening disease worldwide. Ferroptosis is a newly discovered form of regulated cell death, which involves the accumulation of iron-dependent lipid peroxides. It has been found that ferroptosis plays an important regulatory role in the occurrence, development, drug resistance, and prognosis of GC. Non-coding RNAs (ncRNAs) play a critical role in the occurrence and progression of a variety of diseases including GC. In recent years, the role of ferroptosis and ferroptosis-related ncRNAs (miRNA, lncRNA, and circRNA) in the occurrence, development, drug resistance, and prognosis of GC has attracted more and more attention. Herein, we briefly summarize the roles and functions of ferroptosis and ferroptosis-related ncRNAs in GC tumorigenesis, development, and prognosis. We also prospected the future research direction and challenges of ferroptosis and ferroptosis-related ncRNAs in GC.
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- 2022
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12. Cigarette Smoke-Induced Gastric Cancer Cell Exosomes Affected the Fate of Surrounding Normal Cells via the Circ0000670/Wnt/β-Catenin Axis
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Zhaofeng Liang, Shikun Fang, Yue Zhang, Xinyi Zhang, Yumeng Xu, Hui Qian, and Hao Geng
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gastric cancer ,cigarette smoke ,circRNA ,exosomes ,Wnt/β-catenin ,Chemical technology ,TP1-1185 - Abstract
Cigarette smoke is a major risk factor for gastric cancer. Exosomes are an important part of intercellular and intra-organ communication systems and can carry circRNA and other components to play a regulatory role in the occurrence and development of gastric cancer. However, it is unclear whether cigarette smoke can affect exosomes and exosomal circRNA to promote the development of gastric cancer. Exosomes secreted by cancer cells promote cancer development by affecting surrounding normal cells. Herein, we aimed to clarify whether the exosomes secreted by cigarette smoke-induced gastric cancer cells can promote the development of gastric cancer by affecting the surrounding gastric mucosal epithelial cells (GES-1). In the present study, we treated gastric cancer cells with cigarette smoke extract for 4 days and demonstrated that cigarette smoke promotes the stemness and EMT of gastric cancer cells and cigarette smoke-induced exosomes promote stemness gene expression, EMT processes and the proliferation of GES-1 cells. We further found that circ0000670 was up-regulated in tissues of gastric cancer patients with smoking history, cigarette smoke-induced gastric cancer cells and their exosomes. Functional assays showed that circ0000670 knockdown inhibited the promoting effects of cigarette smoke-induced exosomes on the stemness and EMT characteristic of GES-1 cells, whereas its overexpression had the opposite effect. In addition, exosomal circ0000670 was found to promote the development of gastric cancer by regulating the Wnt/β-catenin pathway. Our findings indicated that exosomal circ0000670 promotes cigarette smoke-induced gastric cancer development, which might provide a new basis for the treatment of cigarette smoke-related gastric cancer.
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- 2023
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13. Dithiol surface treatment towards improved charge transfer dynamic and reduced lead leakage in lead halide perovskite solar cells
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Qingrui Wang, Zhenhua Lin, Jie Su, Yumeng Xu, Xing Guo, Yingchun Li, Miao Zhang, Jincheng Zhang, Jingjing Chang, and Yue Hao
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charge transfer ,dithiol ,lead leakage ,perovskite solar cells ,surface treatment ,Renewable energy sources ,TJ807-830 ,Environmental sciences ,GE1-350 - Abstract
Abstract With efficiency surpassing 25%, perovskite solar cells (PSCs) have received much attention because of their excellent potential in photovoltaic field. However, there are some challenging issues still exist which need to be addressed. One issue is that the surface/interface and grain boundaries related defects and traps could work as charge recombination centers during the device operation, compromising the charge transfer as well as the device performance. Another issue is the leakage of toxic Pb, which may cause undesired contamination to water or soil and make devices not appropriate to work outdoors. Herein, the dithiol molecule was introduced to passivate surface defects and traps as well as reduce the Pb leakage. The unsaturated Pb2+ usually acting as recombination centers could coordinate with thiol group to reduce the recombination. Meanwhile, the beneficial band bend was observed, which facilitates the interface charge transfer. Crucially, we confirmed dithiol molecule could help reduce the Pb leakage. Retarded dissolution of PbI2 into water was observed for perovskite films after dithiol treatment, which eventually contributed less Pb leakage. Overall, this study proposes a universal strategy for defects passivation and reduced lead leakage, which is promising for environmental stable optoelectronic applications.
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- 2022
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14. The Association Between Serum Palmitic Acid and Thyroid Function
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Guowei Zhou, Yumeng Xu, Yuqing Zhai, Zhen Gong, Kun Xu, Gaoyuan Wang, Chenhua Sun, and Chaoqun Ma
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palmitic acid ,thyroid function ,cross-sectional analysis ,free thyroxine ,NHANES ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
AimEmerging evidence indicates that palmitic acid (PA) can regulate the progression and development of many diseases. However, the studies examining the association between PA and thyroid function remain sparse. We aimed to investigate the association between serum PA (sPA) and thyroid function in the US population.MethodsIn this retrospective study, a cross-sectional analysis was performed using the data pooled from the database of the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2012. The thyroid parameters investigated were mainly free triiodothyronine (FT3), free thyroxine (FT4), total T3 (TT3), TT4, thyroglobulin (Tg), thyroid-stimulating hormone (TSH), anti-thyroglobulin antibody (TgAb), and anti-thyroperoxidase antibody (TPOAb). The central sensitivity to thyroid function was evaluated by the thyroid feedback quantile-based index (TFQI), thyrotrophin thyroxine resistance index (TT4RI), and thyrotropin index (TSHI). The FT3 to FT4 ratio (FT3/FT4) was employed to evaluate peripheral sensitivity to thyroid hormones. Multiple imputation was applied to handle the missing data, and weighted multivariable linear regression, subgroup, and interaction analyses were then employed to estimate the association between sPA and thyroid parameters.ResultsIn the 737 adults, after adjusting covariates, we demonstrated a significant negative association between sPA and FT4 [β = -1.078, 95% confidence interval (CI): -1.729 to -0.427], as well as a positive relationship between sPA and FT3/FT4 ratio (β = 0.073, 95% CI: 0.044 to 0.102). These results did not change on multiple imputations. In the subgroup analyses, the associations were more significant in male and obese subjects.ConclusionThis investigation demonstrated the significant correlation between sPA and thyroid dysfunction, which suggested the close relationship between lipotoxicity and hypothyroidism or subclinical hypothyroidism. Future research is required to confirm these findings.
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- 2022
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15. A Novel Nomogram Based on a Competing Risk Model Predicting Cardiovascular Death Risk in Patients With Chronic Kidney Disease
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Ning Li, Jingjing Zhang, Yumeng Xu, Manshu Yu, Guowei Zhou, Yawei Zheng, Enchao Zhou, Weiming He, Wei Sun, Lingdong Xu, and Lu Zhang
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nomogram ,chronic kidney disease ,competing risk model ,cardiovascular death ,prediction model ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
ObjectiveChronic kidney disease (CKD) patients are more likely to die from cardiovascular disease (CVD) than develop renal failure. This study aimed to develop a new nomogram for predicting the risk of cardiovascular death in CKD patients.MethodsThis study enrolled 1656 CKD patients from NHANES 2003 to 2006 survey. Data sets from 2005 to 2006 survey population were used to build a nomogram for predicting the risk of cardiovascular death, and the nomogram was validated using data from 2003 to 2004 survey population. To identify the main determinants of cardiovascular death, we performed univariate analysis and backward-stepwise regression to select the key factors. The probability of cardiovascular death for each patient in 5, 7, and 9 years was calculated using a nomogram based on the predictors. To assess the nomogram’s performance, the area under receiver operating characteristic curve (AUC) and the calibration curve with 1,000 bootstraps resamples were utilized. The prediction model’s discrimination was examined using cumulative incidence function (CIF).ResultsAge, homocysteine, potassium levels, CKD stage, and anemia were included in the nomogram after screening risk factors using univariate analysis and backward-stepwise regression. Internal validation revealed that this nomogram possesses high discrimination and calibration (AUC values of 5–, 7–, and 9-years were 0.79, 0.81, and 0.81, respectively). External validation confirmed the same findings (AUC values of 5–, 7– and 9-years were 0.76, 0.73, and 0.73, respectively). According to CIF, the established nomogram effectively differentiates patients at a high risk of cardiovascular death from those at low risk.ConclusionThis work develops a novel nomogram that integrates age, homocysteine, potassium levels, CKD stage, and anemia and can be used to more easily predict cardiovascular death in CKD patients, highlighting its potential value in clinical application.
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- 2022
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16. Circular RNA and Its Roles in the Occurrence, Development, Diagnosis of Cancer
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Yue Zhang, Xinyi Zhang, Yumeng Xu, Shikun Fang, Ying Ji, Ling Lu, Wenrong Xu, Hui Qian, and Zhao Feng Liang
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circRNAs ,biogenesis ,cancer ,biomarkers ,mechanisms ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Circular RNAs (circRNAs) are non-coding single-stranded covalently closed circular RNA, mainly produced by reverse splicing of exons of precursor mRNAs (pre-mRNAs). The characteristics of high abundance, strong specificity, and good stability of circRNAs have been discovered. A large number of studies have reported its various functions and mechanisms in biological events, such as the occurrence and development of cancer. In this review, we focus on the classification, characterization, biogenesis, functions of circRNAs, and the latest advances in cancer research. The development of circRNAs as biomarkers in cancer diagnosis and treatment also provides new ideas for studying circRNAs research.
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- 2022
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17. Adaptive Fuzzy Observer-Based Command Filtered Discrete-Time Control for PMSMs With Input Constraint
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Yumeng Xu, Jiapeng Liu, Qixin Lei, Yumei Ma, and Jinpeng Yu
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Command filtered backstepping ,adaptive fuzzy observer ,input constraint ,discrete-time ,permanent magnet synchronous motors ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
This paper proposes an adaptive fuzzy observer-based command filtered discrete-time control method for permanent magnet synchronous motors (PMSMs) with input constraint. First, the rotor angular velocity is estimated by using an adaptive fuzzy observer and the unknown nonlinear function is approximated by using fuzzy logic systems (FLSs) in the PMSMs drive systems. Then, compared with the traditional backstepping method, command filtered backstepping method is developed to solve the “complexity of computation” problem. It is shown that all signals of the closed-loop system are semi-globally uniformly ultimately bounded. Finally, the results of the simulation and experiment demonstrate that the new design method can fully consider the influence of input constraint and load disturbance, and improve the tracking performance for PMSMs drive systems.
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- 2021
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18. Hesperidin Reversed Long-Term N-methyl-N-nitro-N-Nitroguanidine Exposure Induced EMT and Cell Proliferation by Activating Autophagy in Gastric Tissues of Rats
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Zhaofeng Liang, Jiajia Song, Yumeng Xu, Xinyi Zhang, Yue Zhang, and Hui Qian
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gastric cancer ,MNNG ,hesperidin ,autophagy ,PI3K/AKT ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Gastric cancer is a common malignant tumor worldwide. N-methyl-N-nitro-N-nitroguanidine (MNNG) is one of the most important inducing factors of gastric cancer. Autophagy can affect the occurrence and development of gastric cancer, but the mechanism is not clear. Chemoprevention has been shown to be a rational and very promising approach to the prevention of gastric cancer. Hesperidin is a citrus flavone, an abundant polyphenol in citrus fruits and traditional Chinese medicine. It has an excellent phytochemistry that plays an intervention role in gastric cancer. However, it is unclear whether long-term exposure to MNNG will affect the occurrence of gastric cancer by regulating autophagy and whether hesperidin can play an intervention role in this process. In the present study, we demonstrated that long-term MNNG exposure inhibits autophagy in stomach tissues of rats, promotes the epithelial–mesenchymal transition (EMT) process and cell proliferation and suppresses the activity of the PI3K/AKT pathway. We further found that after rapamycin-activated autophagy, long-term MNNG exposure promoted cell proliferation and EMT were inhibited. In addition, hesperidin promotes autophagy and the activity of the PI3K/AKT pathway, as well as the suppression of proliferation and EMT in the stomach tissues of rats. Our findings indicate that hesperidin reverses MNNG-induced gastric cancer by activating autophagy and the PI3K/AKT pathway, which may provide a new basis for the early prevention and treatment of MNNG-induced gastric cancer.
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- 2022
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19. Passivation Effect on ZnO Films by SF6 Plasma Treatment
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Yumeng Xu, Baoxue Bo, Xin Gao, and Zhongliang Qiao
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ZnO ,SF6 ,passivation ,Crystallography ,QD901-999 - Abstract
The passivation effects of SF6 plasma on zinc oxide (ZnO) films prepared by magnetron sputtering were researched. After the SF6 plasma passivation of ZnO films, the grain size increases, there is low surface roughness, and a small amount of Zn-F bonds are formed, resulting in the narrowing of band gap. The photoluminescence (PL) intensity of SF6-passivated ZnO films has a 120% increase compared to the untreated samples, and the reduction in defects can increase the resistivity and stability of ZnO films. ZnO films are used in the preparation of ZnO/p-Si heterojunction diodes. The results of the measurement of current voltage (J−V) show that the reverse current is reduced after SF6 plasma passivation, indicating an improvement in the electrical properties of ZnO films.
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- 2019
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20. Effects on the Surface and Luminescence Properties of GaAs by SF6 Plasma Passivation
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Yumeng Xu, Xin Gao, Xiaolei Zhang, Zhongliang Qiao, Jing Zhang, Lu Zhou, and Baoxue Bo
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passivation ,GaAs ,SF6 ,plasma ,radio frequency ,Crystallography ,QD901-999 - Abstract
The passivation effects of the SF6 plasma on a GaAs surface has been investigated by using the radio frequency (RF) plasma method. The RF’s power, chamber pressure, and plasma treatment time are optimized by photoluminescence (PL), atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). The PL intensity of passivated GaAs samples is about 1.8 times higher than those which are untreated. The oxide traps and As-As dimers can be removed effectively by using SF6 plasma treatment, and Ga-F can form on the surface of GaAs. It has also been found that the stability of the passivated GaAs surface can be enhanced by depositing SiO2 films onto the GaAs surface. These indicate that the passivation of GaAs surfaces can be achieved by using SF6 plasma treatment.
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- 2018
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21. Boosting Multi-Block Repair in Cloud Storage Systems with Wide-Stripe Erasure Coding.
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Qi Yu, Lin Wang, Yuchong Hu, Yumeng Xu, Dan Feng 0001, Jie Fu, Xia Zhu, Zhen Yao, and Wenjia Wei
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- 2023
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22. Adaptive Neural Networks Command Filtered Control for MIMO Nonlinear Discrete-Time Systems With Input Constraint.
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Yumeng Xu, Jiapeng Liu, Jinpeng Yu 0001, and Qing-Guo Wang
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- 2023
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23. Two-Stage Octave Residual Network for End-to-End Image Compression.
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Fangdong Chen, Yumeng Xu, and Li Wang
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- 2022
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24. Shielding-Sensing Integrated Multilayer PET–Carbon Nanotube Composites for 5G Applications
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Yunbo Guo, Andreas Rosenkranz, Yumeng Xu, and Yinxiang Lu
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Materials Chemistry ,Electrochemistry ,Electronic, Optical and Magnetic Materials - Published
- 2022
25. Enhanced anaerobic digestion of waste activated sludge by alkaline protease-catalyzing hydrolysis: Role and significance of initial pH adjustment
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Heliang Pang, Yumeng Xu, Ruiyao Ren, Junguo He, Xinlei Pan, and Ling Wang
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General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
26. The effect of phytochemicals in Nmethyl-N-nitro-N-nitroguanidine promoting the occurrence and development of gastric cancer.
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Ling Lu, Bei Chen, XinYi Zhang, Yumeng Xu, Longtao Jin, Hui Qian, and Zhao feng Liang
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STOMACH cancer ,HELICOBACTER pylori infections ,NUTS ,INHIBITION of cellular proliferation ,CARCINOGENESIS ,PHYTOCHEMICALS - Abstract
Gastric cancer is a common malignant tumor of the digestive tract, with a low early diagnosis rate. N-methyl-N-nitro-N-nitroguanidine (MNNG) is one of the main risk factors for gastric cancer. Phytochemicals are healthy active substances derived from vegetables, fruits, nuts, tea, herbal medicines and other plants. Taking phytochemicals is a very promising strategy for the prevention and treatment of gastric cancer. Many studies have proved that phytochemicals have protective effects on MNNG induced gastric cancer via inhibiting cell proliferation, enhancing immunity, suppressing cell invasion and migration, inducing apoptosis and autophagy, blocking angiogenesis, inhibiting Helicobacter pylori infection as well as regulating metabolism and microbiota. The intervention and therapeutic effects of phytochemicals in MNNG induced gastric cancer have attracted more and more attention. In order to better study and explore the role, advantages and challenges of phytochemicals in MNNG induced gastric cancer, we summarized the intervention and therapeutic effects of phytochemicals in MNNG induced gastric cancer. This review may help to further promote the research and clinical application of phytochemicals in MNNG induced gastric cancer, and provide some new insights. [ABSTRACT FROM AUTHOR]
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- 2023
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27. Enhanced electromagnetic-interference shielding effectiveness and mechanical strength of Co-Ni coated aramid-carbon blended fabric
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Qin Wang, Siyi Bi, Yumeng Xu, and Yinxiang Lu
- Subjects
0209 industrial biotechnology ,Toughness ,Materials science ,Scanning electron microscope ,Mechanical Engineering ,Composite number ,Alloy ,Aerospace Engineering ,02 engineering and technology ,engineering.material ,01 natural sciences ,010305 fluids & plasmas ,Aramid ,020901 industrial engineering & automation ,X-ray photoelectron spectroscopy ,0103 physical sciences ,Electromagnetic shielding ,Ultimate tensile strength ,engineering ,Composite material - Abstract
An efficient method was proposed to prepare high-performance conductive Aramid-Carbon Blend Fabrics (ACBF) with cobalt-nickel (Co-Ni) alloy coatings, which is conducive to industrial production. The grid-like substrate composed of aramid and carbon fibers was innovatively used in flexible ElectroMagnetic Interference (EMI) shielding materials. The natural network structure is advantageous to the uniform deposition of metal particles to the establishment of conductive pathways subsequently in order to improve conductivity. The induction of a synergistic effect from ElectroMagnetic (EM) wave-reflection and EM wave-absorption through the whole carbon-Co-Ni-ternary system notably enhanced the EMI Shielding Effectiveness (SE) value to an average of 42.57 dB in the range of 30−6000 MHz. On the other hand, together with the inherent toughness of the alloy coatings, the tensile strength of the aramid fibers used for bulletproof made a significant contribution to the desired mechanical properties. The light weight of the resultant composite made it applicable to aerospace vehicles simultaneously. X-ray Photoelectron Spectroscopy (XPS) was conducted to investigate the variations of elements and groups on the sample surface in pre-treating process. The elemental components and surface morphologies of fabric samples during different stages of the process were investigated by Scanning Electron Microscope (SEM) and Energy Dispersive spectrometer (EDX) measurements. X-Ray Diffraction (XRD) results indicated that the obtained Co-Ni alloy coating had a combined Hexagonal Closed-Packed (HCP) and Faced-Centered Cubic (FCC) crystalline phase. The relatively high corrosion resistance demonstrated in different acid and alkaline conditions was instrumental in more complex environments as well.
- Published
- 2021
28. Hesperidin inhibits tobacco smoke‑induced pulmonary cell proliferation and EMT in mouse lung tissues via the p38 signaling pathway
- Author
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Zhaofeng, Liang, Yue, Zhang, Yumeng, Xu, Xinyi, Zhang, and Yanan, Wang
- Subjects
Cancer Research ,Oncology - Abstract
Tobacco smoke (TS) is the major cause of lung cancer. The abnormal proliferation and epithelial-mesenchymal transition (EMT) of lung cells promote occurrence and development of lung cancer. The p38 pathway intervenes in this cancer development. Hesperidin also serves a role in human health and disease prevention. The roles of p38 in TS-mediated abnormal cell proliferation and EMT, and the hesperidin intervention thereof are not yet understood. In the present study, it was demonstrated that TS upregulated proliferating cell nuclear antigen, vimentin and N-cadherin expression, whereas it downregulated E-cadherin expression, as assessed using western blotting and reverse transcription-quantitative PCR. Furthermore, it was observed that inhibition of the p38 pathway inhibit TS-induced proliferation and EMT. Hesperidin treatment prevented the TS-induced activation of the p38 pathway, EMT and cell proliferation in mouse lungs. The findings of the present study may provide insights into the pathogenesis of TS-related lung cancer.
- Published
- 2022
29. Measurability of precession and eccentricity for heavy binary-black-hole mergers
- Author
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Yumeng Xu and Eleanor Hamilton
- Subjects
FOS: Physical sciences ,General Relativity and Quantum Cosmology (gr-qc) ,General Relativity and Quantum Cosmology - Abstract
Gravitational wave detections offer insights into the astrophysical populations of black holes in the universe and their formation processes. Detections of binaries consisting of black holes lying outside the bulk distribution of the astrophysical population are particularly intriguing. In this study, we perform an injection analysis within the intermediate-mass black hole range, utilizing the NR surrogate model NRSur7dq4 and a selection of NR waveforms from the SXS and RIT catalogues. Our investigation focuses on the detectability of precession and its potential degeneracy with eccentricity, especially for short signals with only a few cycles in band. While total mass, mass ratio, and $\chi_\mathrm{eff}$ are generally well recovered, the recovery of $\chi_\mathrm{p}$ is largely limited, and noise significantly impacts the recovery of some parameters for short signals. We also find that eccentricity lower than 0.2 is insufficient to mimic precession in parameter estimation when assuming a quasi-circular signal. Our results suggest that a certain degree of precession is necessary to produce evidence of high precession in parameter estimation, but it remains challenging to conclusively determine which effect is responsible for the high precession observed in events like GW190521. We emphasize the importance of caution when interpreting properties of a binary from short signals and highlight the potential benefits of future third generation detectors and eccentric waveform models for more exhaustive exploration of parameter space., Comment: 16 pages, 13 figures
- Published
- 2022
30. Synergistic Effect of Surface p-Doping and Passivation Improves the Efficiency, Stability, and Reduces Lead Leakage in All-Inorganic CsPbIBr
- Author
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Jian, He, Qingrui, Wang, Yumeng, Xu, Xing, Guo, Long, Zhou, Jie, Su, Zhenhua, Lin, Jincheng, Zhang, Yue, Hao, and Jingjing, Chang
- Abstract
Wide-bandgap inorganic cesium lead halide CsPbIBr
- Published
- 2022
31. Mechanochemical modified nitrogen-rich biochar derived from shrimp shell: Dominant mechanism in pyridinic-N for aquatic methylene blue removal
- Author
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Ming Wang, Jinlong Yan, Yumeng Xu, Xiangqian Zhou, Yusen Diao, Hui Wang, Jiahao Bian, Cheng Liu, and Guixiang Quan
- Subjects
Environmental Engineering ,General Medicine ,Management, Monitoring, Policy and Law ,Waste Management and Disposal - Abstract
N-doping for the preparation of functional carbon materials is a trending research topic. In this study, N-rich biochar (BC) was prepared by calcining naturally N rich shrimp shells under oxygen-limiting environment, and the calcining temperatures were controlled. BC were activated with 5% hydrochloric acid solutions and then post-modified with ball-milling to obtain a series of novel adsorbents (MBCs). All samples were characterized by SEM, BET, FT-IR, XRD, XPS, TG, and element analysis. Surface area, pore volume, and other surface functional groups were significantly improved after acidizing and ball-milling. The adsorption capacities for MB were MBC350 MBC500 MBC650BC350 BC650 BC500, and the equilibrium adsorption capacities were 575.01 mg/g, 506.52 mg/g, 424.59 mg/g, 113.31 mg/g, 93.53 mg/g and 86.25 mg/g, respectively. The excellent adsorption performance of MBCs for MB was ascribed to Lewis acid-base interaction, π-π interaction, electrostatic interaction and van der Waals, and the quinone group and pyridinic-N on the surface of the MBCs are identified as the major active sites. Taken together, ball-milled shrimp shell biochar is a promising material for cation dye adsorption.
- Published
- 2022
32. Feasibility of membrane distillation brine assistant anaerobic fermentation for enhancing carbon migration and recovery from excess sludge: Two wastes into one resource
- Author
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Heliang Pang, Qiangqiang Jiao, Qiao Wei, Jinxuan Liu, Yuyao Zhang, Yumeng Xu, Dong Xu, Junguo He, and Jinsuo Lu
- Subjects
General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
33. Mitigating fungi-related nitrous oxide emissions by application of industrial waste in an acidic soil
- Author
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Junhui Yin, Wenjing Cui, Yumeng Xu, Yan Ma, Huaihai Chen, Jingheng Guo, Rui Liu, and Qing Chen
- Subjects
complex mixtures - Abstract
Alkaline industrial wastes to arable soils have the potential to ameliorate soil acidification and improve crop yield. However, the impact of such amendments with N fertilizers on soil nitrous oxide (N2O) emissions and the mechanisms involved remain elusive. Two incubation experiments were conducted to explore the effects of an alkaline amendment (Phosphorus tailing (PT), a waste product of phosphorus mineral flotation process) on N2O emissions and microbial mechanisms from an acidic soil. Four treatments in the first experiment were set as: i) control (CK), ii) urea (U), iii) PT amendment (S) and iv) PT amendment plus urea (S+U). The second experiment was conducted to access the relative contributions of fungi and bacteria to N2O emissions. Results from the first experiment showed that PT amendment significantly increased soil pH from 4.8 to above 6.0, and reduced N2O emissions by an average of 65.7%. Higher N2 emissions and faster O2 consumption were observed after applying the amendment than untreated soils at the end of incubation. PT amendment significantly increased extracellular enzyme activities of leucine aminopeptidase and N-Acetyl-β-glucosaminidase, while significantly decreased activities of β-1, 4-glucosidase and β-cellobiosidase. In comparison to soil with urea, urea with PT amendment raised soil bacteria-related N2O from 9.18% to 18.8% while decreasing fungi-related N2O from 50.5% to 43.2%. These findings suggest that the N2O emissions from acidic soils can be considerably mitigated by application of alkaline industrial wastes. The contribution of fungi should be considered when designing and applying N2O mitigation strategies in acidic soils.
- Published
- 2022
34. Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer
- Author
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Ling Lu, Qiaoyan Liang, Xinyi Zhang, Yumeng Xu, Dehua Meng, and Zhaofeng Liang
- Subjects
Oncology - Abstract
Gastric cancer (GC) is one of the most common malignant cancers that seriously affect human health. Autophagy is a highly conserved self-defense mechanism found to plays an important role in the occurrence, progression, drug resistance, and prognosis of GC. Noncoding RNAs (ncRNAs) play a critical role in the occurrence and development of a variety of diseases including GC. In recent years, increasing attention has been given to research on autophagy-related ncRNAs, such as miRNA, lncRNA, and circRNA in GC. Herein, we briefly summarize the roles, functions, and the research progress of autophagy and autophagy-related ncRNAs in GC with a focus on the potential application in GC tumorigenesis, development, prognosis, and drug resistance. We also discussed prospects of clinical application, future research direction, and challenges in future research of autophagy-related ncRNAs.
- Published
- 2022
35. Smartphone-based polydiacetylene colorimetric sensor for point-of-care diagnosis of bacterial infections
- Author
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Yue Zhou, Yumeng Xue, Xubo Lin, Menglong Duan, Weili Hong, Lina Geng, Jin Zhou, and Yubo Fan
- Subjects
Bacterial infection ,Polydiacetylene (PDA) ,Point-of-care (POCT) ,Antimicrobial susceptibility testing (AST) ,Smartphone-based detection ,Technology - Abstract
The rapid progress in point-of-care testing (POCT) has become a promising decentralized patient-centered approach for the control of infectious diseases, especially in resource-limited settings. POCT devices should be inexpensive, rapid, simple operation and preferably require no power supply. Here, we developed a simple bacterial sensing platform that can be operated by a smartphone for bacteria identification and antimicrobial susceptibility testing (AST) based on using a polydiacetylene (PDA) arrayed membrane chip. Each PDA array produced a unique color ‘fingerprint’ pattern for each bacteria based on different modes of action of toxins from bacteria on biomimetic lipid bilayers within PDA-lipid assemblies. We show that the PDA-based device can detect viable cells of bacteria as low as 104 CFU/mL within 1.5 h compared with several days of conventional bacterial identification, with the aid of a smartphone app. The device can also be used for an antimicrobial susceptibility test (AST) for at least two broad-spectrum antimicrobials within 4 h and provide identification of antimicrobial susceptibility and resistance, enabling the selection of appropriate therapies. This PDA-based sensing platform provides an alternative way for bacterial detection and could be used as a portable and inexpensive POCT device for the rapid detection of bacterial infection in limited-resource settings.
- Published
- 2024
- Full Text
- View/download PDF
36. Insight into Na+ assistant anaerobic fermentation of waste activated sludge from carbon migration, bio-transformation and recovery perspectives
- Author
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Heliang Pang, Qiangqiang Jiao, Lei An, Yumeng Xu, Junguo He, Zhiqiang Zhang, and Jinsuo Lu
- Subjects
Filtration and Separation ,Analytical Chemistry - Published
- 2023
37. Primary malignant tumours and malignant transformation of cysts in the retrorectal space: MRI diagnosis and treatment outcomes
- Author
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Jing Gong, Yumeng Xu, Yan Zhang, Lichao Qiao, Haixia Xu, Ping Zhu, and Bolin Yang
- Subjects
Gastroenterology - Abstract
Background There are no clear guidelines for the diagnosis and treatment of malignant retrorectal tumours. The purpose of this study was to increase preoperative diagnostic knowledge and to describe the outcomes of treatment for these patients. Methods This retrospective study was conducted on patients who underwent complete retrorectal tumour resection between May 2006 and July 2018, and had confirmed post-operative pathology reports. Demographic and clinical data (including imaging, perioperative, pathological, and prognostic data) were collected and analysed. Results Malignant lesions were identified in 15 (9 [60%], female) patients. The median age of the patients was 59 years (range, 34–72 years). Primary malignant tumours were identified in seven patients with solid tumours, in which gastrointestinal stromal tumours accounted for 71.4% (five of seven) and the remainder were chordoma or mucinous adenocarcinoma. Malignant transformation of cysts occurred in another eight patients with heterogeneous tumours, while histopathological features were present in 75% (six of eight) of patients with mucinous adenocarcinoma, and the remainder were squamous-cell carcinoma or neuroendocrine tumour (Grade 2). The malignant characteristics of the solid portions observed using magnetic resonance imaging (MRI) were as follows: the cyst wall of the tumour was irregularly thickened; the surface was convex or lobed; the solid tumour had no capsule, or the capsule was destroyed; and the surface had a gyrus-like morphology. At a median follow-up time of 52 months (range, 13–100 months), the overall recurrence-free survival rate was 40.0% and the survival rate was 46.7%. Conclusion Some MRI features can be used to distinguish malignant retrorectal tumours from benign retrorectal tumours. The survival rate of patients with malignant retrorectal tumours is poor.
- Published
- 2022
38. Sandwich-shaped multifunctional electromagnetic shielding material based on fiber–carbon nanotube system
- Author
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Yumeng Xu, Yinxiang Lu, Siyi Bi, and Zefeng Zhang
- Subjects
010302 applied physics ,Nanotube ,Materials science ,Composite number ,Carbon nanotube ,Epoxy ,Condensed Matter Physics ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,law.invention ,Thermal conductivity ,law ,Elemental analysis ,Electrical resistivity and conductivity ,visual_art ,0103 physical sciences ,Electromagnetic shielding ,visual_art.visual_art_medium ,Electrical and Electronic Engineering ,Composite material - Abstract
In this article, a novel flexible, wearable material with great EMI shielding performance was prepared through structuring fiber–carbon nanotube composite system. The composite possessed satisfactory heating performance and glucose-sensing characteristics, based on its excellent electrical conductivity and thermal conductivity. The carbon nanotube and epoxy resin composite material was cured by isopachous-rolling-shaping (IRS) process without sensitization. Under the optimal processing condition, the resultant sample showed a high electrical conductivity of 1.19 × 106 S m−1, the saturation magnetization of 4.83 emu/g. Surface morphologies, functional groups, and elemental analysis of composite were characterized by SEM and ATR-FTIR, respectively. Remarkably, the multilayer material exhibited favorable electromagnetic shielding performance with effectiveness of 60.9 dB (30–6000 MHz). In addition, it could stably heat up to 45 °C at a constant voltage of 3 V. Excellent electrocatalytic performance for glucose oxidation was shown in 0.1 mM NaOH solution, with the sensitivity up to 10190.35 μA mM−1 cm−2. By virtue of mutual reinforcement between multiwalled carbon nanotubes (MWNTs) and epoxy resin composites (RC), excellent electromagnetic properties and serviceability were obtained, which resulted in high durability for practical applications in electronic device engineering.
- Published
- 2020
39. Bio-inspired Fabrication of Cu-Ni Coatings onto Mercerized Flax Fabric by Electroless Plating
- Author
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Yumeng Xu, Bijian Lan, Yinxiang Lu, Lei Hou, Hang Zhao, Siyi Bi, and Lin Zhu
- Subjects
Grammage ,Fabrication ,Materials science ,Polymers and Plastics ,General Chemical Engineering ,02 engineering and technology ,General Chemistry ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,X-ray photoelectron spectroscopy ,Coating ,Plating ,Electromagnetic shielding ,engineering ,Atomic ratio ,Composite material ,Fourier transform infrared spectroscopy ,0210 nano-technology - Abstract
This research mainly prepared a bio-friendly electromagnetic interference (EMI) shielding fabric, and discussed the influence of the grammage (i.e. 120 g/m2, 160 g/m2 and 210 g/m2, etc) of fabric substrate on the preparation of metal-based EMI shielding conductive fabric by electroless plating. A series of steps involved mercerization, dopamine (DoPA) modification, Ni0 seeding and electroless copper-nickel (Cu-Ni) plating were carried out to fabricate ideal EMI shielding fabric. The prepared Cu-Ni fabric endowed relatively high EMI shielding effectiveness (SE) (34.80-42.00 dB) ranging from 30 to 4500 MHz, which made it a huge potential in the field of wearable EMI shielding. Moreover, another discovery was that a relative higher grammage may lead to a lower total metal loading. Furthermore, Fourier transformation infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS) measurements were conducted to verify the introduction of functional groups in mercerization, modification and activation procedures. The crystalline phases and morphologies of resulting Cu-Ni coatings were characterized by X-ray diffraction (XRD) and field emission-scanning electron microscopy (FE-SEM) measurements. The atomic ratio (at.%) of Cu and Ni in the sample was determined by Energy Dispersive X-ray Spectroscopy (EDX) measurements. Overall, the Cu-Ni alloy fabric prepared in this research met the requirements of health, coating lining and EMI shielding.
- Published
- 2020
40. Flexible perovskite solar cells: Material selection and structure design
- Author
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Yumeng Xu, Zhenhua Lin, Jincheng Zhang, Yue Hao, Jianyong Ouyang, Shengzhong Liu, and Jingjing Chang
- Subjects
General Physics and Astronomy - Abstract
With the rapid development of the Internet of Things, convenient and portable self-powered devices are in great need. Among all substitutes that could provide clean and sustainable power, the flexible perovskite solar cells (FPSCs) are the most attractive with the characteristics of flexibility, lightweight, high power conversion efficiency, and low cost. In this review, the recent advances of FPSCs are summarized, focusing on the materials' assessment of flexible and durable substrate, transparent electrode, low-temperature processed charge transporting layer, and mechanically robust perovskite film, with device design interspersed in each part. Finally, the challenges of FPSCs in terms of higher efficiency, higher flexibility, higher stability, and scalable fabrication are summarized.
- Published
- 2022
41. Ultrasensitive and highly flexible nonenzymatic glucose biosensor based on laser-scribed carbon paper substrate
- Author
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Lin Zhu, Hang Zhao, Lei Hou, Siyi Bi, Yumeng Xu, and Yinxiang Lu
- Subjects
Detection limit ,chemistry.chemical_classification ,Materials science ,Central composite design ,Biomolecule ,General Physics and Astronomy ,Substrate (chemistry) ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,Conductivity ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Linear range ,Chemical engineering ,chemistry ,Specific surface area ,0210 nano-technology ,Biosensor - Abstract
Owing to the high specific surface area and easy accessability to targeting biomolecules, emerging non-noble-metal networks are developed as an ultra-active catalyst for molecular detection. In this work, a facile flexible enzyme-free glucose sensor with superior sensing performance has been successfully constructed by integrating laser-scribed carbon paper (LSCP) with copper network (CN). Remarkably, operation parameters are modeled and optimized by Central Composite Design (CCD) to obtain an optimal conductivity of 4.783 × 107 S·m−1 for CN. Due to the great electronic/ionic pathway between LSCP of ample active sites and CN of excellent conductivity, the disposable biosensor exhibits fast electron transfer kinetics. For glucose detection, LSCP/CN exhibits an excellent sensitivity of 3626.6 μA mM−1 cm−2, a wide linear range from 1 μM to 7.96 mM, an ultra-low detection limit of 30 nM (S/N = 3) as well as favorable reusability. Satisfactory anti-interference capacity to electro-active oxides and selectivity against carbohydrates studied for concentrations up to normal physiologic levels and higher concentrations are systematically investigated. The applications of glucose determination in human serum and perspiration samples are also successful, with recoveries of 100.8% (± 2.28%) and 92.1% (±3.61%), respectively. Experimentally, the current response of the LSCP/CN biosensor is resilient to mechanical deformation with less than 8% decay even after 1000 cycles of 1 mm repeated bending and 180° cyclical folding tests. As such, LSCP/CN can be applicable for flexible, attachable and potentially wearable biosensors to attain real-time physiological monitoring.
- Published
- 2019
42. Alumina sandpaper-supported nickel nanocoatings and its excellent application in non-enzymatic glucose sensing
- Author
-
Lin Zhu, Yinxiang Lu, Hang Zhao, Siyi Bi, Yumeng Xu, and Lei Hou
- Subjects
Detection limit ,Materials science ,General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Crystallinity ,Nickel ,X-ray photoelectron spectroscopy ,Linear range ,Chemical engineering ,chemistry ,Superhydrophilicity ,0210 nano-technology ,Sandpaper - Abstract
A novel non-enzymatic glucose sensor was developed based on sandpaper-supported nickel coatings (SNC). Superhydrophilic network was formed on the surface of sandpaper via a simple laser-scribing (LS) method. Orthogonal model was utilized to optimize the processing parameters for preparing SNC with an optimal conductivity of 4.20 × 106 S·m−1. The surface morphology, functional groups and elements of SNC were characterized by SEM, ATR-FTIR and XPS respectively. The crystallinity of nickel nanocoating was determined by XRD. Remarkably, the SNC exhibited favorable electrocatalytic performance with a wide linear range (LR) of 0.01–4.3 mM, a high sensitivity of 1163.3 μA mM−1 cm−2 and a low limit of detection (LOD) of 0.250 μM, which was measured by standard electrochemical measurements. Low relative standard deviation (0.59% and 0.72%, n = 6) and high recoveries (96.30–97.78%) verified its stability and reusability, which can meet the needs of daily uses. Finally, successful application of the SNC to the analysis of glucose in human serum samples, leading to a promising tool for non-enzymatic glucose determination in healthcare and food industries.
- Published
- 2019
43. Detection of Basic Emotions from Cats’ Meowing
- Author
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Yumeng Xu, Qianlong Shou, Min Huang, Junjun Jiang, and Zhongzhe Xiao
- Subjects
Facial expression ,Zero-crossing rate ,Speech recognition ,Emotion classification ,Feature (machine learning) ,Body movement ,Mel-frequency cepstrum ,Valence (psychology) ,Psychology ,LogitBoost - Abstract
Basic emotional states in valence sense as positive, neutral, and negative are studied with automatic classification on cats’ meowing signals, aiming to help human-cat interaction and human emotion regulation by pets keeping. The ground truth of meowing samples is marked by subjective evaluation from multiple raters with the help of cats’ facial expression, body movement, and interaction with cat owners in video clips. Acoustic features extracted from voice energy, zero crossing rate, and MFCC are proved to be effective in cats’ emotion recognition. The highest accuracy reaches 97.40% on selected best feature subset with LogitBoost model.
- Published
- 2021
44. Implementation of Machine Learning-Aided Imaging Analytics for Histopathological Image Diagnosis
- Author
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Aileen Wee, Ha Eun Chun, Eliza Li Shan Fong, Jiahao Wang, Yang Yu, Hanry Yu, and Yumeng Xu
- Subjects
Computer science ,Analytics ,business.industry ,Artificial intelligence ,business ,Machine learning ,computer.software_genre ,computer ,Image diagnosis - Published
- 2021
45. Effect of solvent polarity on surface characteristics and luminescent properties of octadecanethiol passivated GaAs
- Author
-
Xin Gao, Baoxue Bo, and Yumeng Xu
- Subjects
congenital, hereditary, and neonatal diseases and abnormalities ,Materials science ,Photoluminescence ,Passivation ,Analytical chemistry ,Oxide ,nutritional and metabolic diseases ,chemistry.chemical_compound ,chemistry ,X-ray photoelectron spectroscopy ,Molecule ,Methanol ,Luminescence ,Layer (electronics) - Abstract
In order to effectively reduce the surface state density of GaAs and obtain a stable high-performance passivation film, the GaAs surface was passivated by using the solution of octadecanethiol in different solvents. The effects of solvent polarity on passivated GaAs surface by octadecyl mercaptan solution were researched by X-ray diffractometry, photoluminescence and atomic force microscopy. The XPS test shows that the methanol compared to ethanol and isopropanol solvents, the surface of the GaAs after passivation has less oxide content, the As-S bond increases, and the density of octadecanethiol molecules attached to the surface increases. The PL measurement shows that the PL intensity of GaAs surface is highest by octadecanethiol methanol solution passivation, and it is 1.65 times higher than non-passivated. The surface stability test shows that the photoluminescence intensity of passivated GaAs surface do not deteriorate significantly after several days in air (PL intensity decreased by 22.1% within 30 days), which indicates that the self-assembled passivation layer of passivated GaAs surface has good stability.
- Published
- 2019
46. Cu–Ni–Gd coating with improved corrosion resistance on linen fabric by electroless plating for electromagnetic interference shielding
- Author
-
Lei Hou, Yumeng Xu, Lin Zhu, Hang Zhao, Yinxiang Lu, and Siyi Bi
- Subjects
Materials science ,chemistry.chemical_element ,Nanoparticle ,02 engineering and technology ,engineering.material ,010402 general chemistry ,01 natural sciences ,Corrosion ,Metal ,Coating ,X-ray photoelectron spectroscopy ,Electrical and Electronic Engineering ,Composite material ,Electrical conductor ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,chemistry ,visual_art ,Electromagnetic shielding ,engineering ,visual_art.visual_art_medium ,0210 nano-technology ,Cobalt - Abstract
The main objective of this research is to fabricate conductive fabrics with good electromagnetic interference (EMI) shielding effectiveness (SE) and improved corrosion resistance. Such conductive fabrics can be prepared by a cost-effective electroless plating method with combination of eco-friendly dopamine (DoPA) self-polymerization technology, which involves successive steps of alkali treatment, 3-aminopropyltrimethoxysilane modification, Cobalt (Co) nanoparticles activation, Copper–Nickel–Gadolinium (Cu–Ni–Gd) deposition and Dopamine (DoPA) self-assembly. The functional groups introduced in modification and activation procedures are verified by FT-IR and XPS measurements. Refined effects of Gd on the structures and morphologies of resulting Cu–Ni–Gd coatings are illustrated by X-ray diffraction and field emission-scanning electron microscopy (FE-SEM) measurements. EMI SE values of Cu–Ni–Gd shielding fabrics are enhanced with increment of 5–7 decibels (dB) ranging from 30 to 4500 MHz compared with that of Gd-free Cu–Ni shielding fabrics. Furthermore, DoPA membrane polymerized on the top of metallic coatings acting as a barrier for corrosion media is demonstrated by measuring the corrosion resistance of DoPA coated shielding fabrics in 3.5wt.% NaCl solution. Overall, Cu–Ni–Gd shielding fabric with excellent EMI SE and durability endow them great potential in EMI shielding application.
- Published
- 2018
47. Artificial intelligence−enhanced white-light colonoscopy with attention guidance predicts colorectal cancer invasion depth
- Author
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Side Liu, Weiguang Qiao, Zelong Han, Yang Yu, Feiyang Huang, Xiaobei Luo, Inn Chuan Ng, Yumeng Xu, Zhenyu Chen, Robby T. Tan, Jiahao Wang, Hanry Yu, Qiang Zhang, and Jianqun Cai
- Subjects
Invasion depth ,Endoscopic Mucosal Resection ,Colorectal cancer ,Colonoscopy ,03 medical and health sciences ,0302 clinical medicine ,Artificial Intelligence ,White light ,medicine ,Humans ,Attention ,Radiology, Nuclear Medicine and imaging ,Receiver operating characteristic ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Endoscopic submucosal dissection ,medicine.disease ,Confidence interval ,Computer-aided diagnosis ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,Artificial intelligence ,Colorectal Neoplasms ,business - Abstract
Background and Aims Endoscopic submucosal dissection (ESD) and EMR are applied in treating superficial colorectal neoplasms but are contraindicated by deeply invasive colorectal cancer (CRC). The invasion depth of neoplasms can be examined by an automated artificial intelligence (AI) system to determine the applicability of ESD and EMR. Methods A deep convolutional neural network with a tumor localization branch to guide invasion depth classification was constructed on the GoogLeNet architecture. The model was trained using 7734 nonmagnified white-light colonoscopy (WLC) images supplemented by image augmentation from 657 lesions labeled with histopathologic analysis of invasion depth. An independent testing dataset consisting of 1634 WLC images from 156 lesions was used to validate the model. Results For predicting noninvasive and superficially invasive neoplasms, the model achieved an overall accuracy of 91.1% (95% confidence interval [CI], 89.6%-92.4%), with 91.2% sensitivity (95% CI, 88.8%-93.3%) and 91.0% specificity (95% CI, 89.0%-92.7%) at an optimal cutoff of .41 and the area under the receiver operating characteristic (AUROC) curve of .970 (95% CI, .962-.978). Inclusion of the advanced CRC data significantly increased the sensitivity in differentiating superficial neoplasms from deeply invasive early CRC to 65.3% (95% CI, 61.9%-68.8%) with an AUROC curve of .729 (95% CI, .699-.759), similar to experienced endoscopists (.691; 95% CI, .624-.758). Conclusions We have developed an AI-enhanced attention-guided WLC system that differentiates noninvasive or superficially submucosal invasive neoplasms from deeply invasive CRC with high accuracy, sensitivity, and specificity.
- Published
- 2021
48. Ultrasensitive and highly selective sandpaper-supported copper framework for non-enzymatic glucose sensor
- Author
-
Yumeng Xu, Lei Hou, Yinxiang Lu, Hang Zhao, and Siyi Bi
- Subjects
Materials science ,Central composite design ,General Chemical Engineering ,Analytical chemistry ,chemistry.chemical_element ,02 engineering and technology ,Conductivity ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,Copper ,0104 chemical sciences ,Linear range ,chemistry ,X-ray photoelectron spectroscopy ,Chemical engineering ,Electrochemistry ,0210 nano-technology ,Porosity ,Sandpaper - Abstract
A simple and cost-effective sandpaper-supported copper framework (SSCF) was innovatively constructed by a novel “scribing-seeding-plating” approach and its application to non-enzymatic glucose determination was systematically investigated. The morphology, composition, crystalline structure of copper nanocoatings and sandpaper substrate were detailedly characterized with SEM, XPS, EDX and XRD, respectively. Processing parameters were optimized by central composite design to obtain an optimal conductivity of 4.69 × 10 7 S·m −1 for copper nanocoatings. The SSCF exhibits excellent performance, with a wide linear range from 1.0 μM to 4.6 mM, a high sensitivity of 2165.5 μA mM −1 cm −2 , a low determination limit of 30 nM (S/N = 3), favorable selectivity and stability. The good electrocatalytic capacity could be attributed to the coordination between high-aspect-ratio porous microstructures of large surface area and copper nanocoatings of excellent catalytic ability. Finally, low relative standard deviations (1.59%–2.76%, n = 10) and good recoveries (101.13%–102.69%) for enzymeless glucose determination in human serum samples and commercial drinks strongly validated satisfactory serviceability of SSCFs in medical diagnostics and food manufacturing.
- Published
- 2017
49. Enhanced reddish-orange emission in NaBa4(BO3)3: Sm3+/Ce3+ phosphors for near-ultraviolet and blue LEDs
- Author
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Wenqin Luo, Junzhe Ren, Renfu Li, Haiyan Wu, Yumeng Xu, Bin Li, Datao Tu, and Xiaoqing Mao
- Subjects
Materials science ,Scanning electron microscope ,Mechanical Engineering ,Analytical chemistry ,Phosphor ,02 engineering and technology ,Crystal structure ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,law.invention ,Ion ,Mechanics of Materials ,law ,General Materials Science ,Emission spectrum ,0210 nano-technology ,Excitation ,Powder diffraction ,Light-emitting diode - Abstract
The Ce3+- and Sm3+-co-doped NaBa4(BO3)3 phosphors were synthesized by a traditional high-temperature solid-state reaction method. The morphology of NaBa4(BO3)3 phosphors was characterized by scanning electron microscope. The crystal structures of Ce3+- and/or Sm3+-doped NaBa4(BO3)3 phosphors were studied by X-ray powder diffraction. The results suggested that Ce3+ occupied the two Ba sites, while Sm3+ might enter into the interstices of NaBa4(BO3)3 crystal. The four emission lines of Ce3+ situating at two Ba2+ sites can be well distinguished by Gaussian fitting. The emission lines from Sm3+ in NaBa4(BO3)3 were significantly enhanced by 25-fold when co-doped with 1 mol% Ce3+ ions. New Sm3+ emission center characterized by the intensified excitation band at around 472 nm was produced as a result of Ce3+ co-doping, which significantly extended the excitation wavelength region for matching both the near-ultraviolet and blue-light-emitting diodes.
- Published
- 2017
50. Electroless plating Cu-Co-P polyalloy on UV/ozonolysis irradiated polyethylene terephthalate film and its corrosion resistance
- Author
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Yinxiang Lu, Hang Zhao, Lei Hou, Siyi Bi, Yuhang Mu, and Yumeng Xu
- Subjects
Materials science ,Scanning electron microscope ,Metallurgy ,General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Copper ,0104 chemical sciences ,Surfaces, Coatings and Films ,Corrosion ,chemistry.chemical_compound ,Surface coating ,chemistry ,X-ray photoelectron spectroscopy ,Attenuated total reflection ,Plating ,Polyethylene terephthalate ,0210 nano-technology ,Nuclear chemistry - Abstract
High corrosion resistant Cu-Co-P coatings were firstly prepared on polyethylene terephthalate (PET) substrate by electroless plating in combination with UV/ozonolysis irradiation under optimized cobalt sulfate heptahydrate concentration, pH value, plating temperature and time. The copper polyalloy/PET composite can be obtained in three steps, namely: (i) the generation of oxygen-containing functionalities (carboxylic groups) onto PET surface through UV irradiation combined with ozone, (ii) Cu seeding catalysts were obtained after being immersed into cupric citrate and NaBH4 solutions subsequently, and (iii) Cu-Co-P polyalloy metallization using electroless plating bath. Attenuated total reflection fourier transformation infrared spectrometer (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), water contact angle measurement and energy dispersive X-ray analysis (EDAX) were utilized to track the surface changes during the whole process. The electroless plating conditions were optimized by an orthogonal experiment (L9(3)4) for Cu-Co-P coating as follows: CoSO4·7H2O addition of 0.08 M, pH value, plating temperature and time were set on 10.0, 35 °C and 25 min, respectively. Under the optimal conditions, copper polyalloy possessed high adhesive strength and the lowest surface resistance (8.06 Ω/sq), while maintaining reliability even after over 1000 times of bending and mechanical stress. The results of scanning electron microscope (SEM) and atomic force microscope (AFM) measurements showed that Cu-Co-P layer formed on PET surface was imparted with fine uniformity and high compactness. Electrochemical test revealed the optimized Cu-Co-P coatings exhibited high corrosion resistance in NaCl, NaOH and HCl solutions, respectively. The excellent electromagnetic interference shielding effectiveness (EMI SE >99.999% at frequency ranging from 30 MHz to 1000 MHz) of copper polyalloy/PET composites was confirmed by the spectrum analyzer. Therefore, this copper polyalloy will have potential applications in microelectronics packaging and coatings for anti-corrosion and electromagnetic interference shielding.
- Published
- 2017
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