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2 results on '"Yuma Sugiura"'

1. Determination of the Chemical Structures of Tandyukisins B–D, Isolated from a Marine Sponge-Derived Fungus

Author

Takeshi Yamada, Yoshihide Umebayashi, Maiko Kawashima, Yuma Sugiura, Takashi Kikuchi, and Reiko Tanaka

Subjects
decalin, Trichoderma harzianum, marine microorganism, Halichondria okadai, cytotoxicity, Biology (General), QH301-705.5
Abstract

Tandyukisins B–D (1–3), novel decalin derivatives, have been isolated from a strain of Trichoderma harzianum OUPS-111D-4 originally derived from the marine sponge Halichondria okadai, and their structures have been elucidated on the basis of spectroscopic analyses using 1D and 2D NMR techniques. In addition, their chemical structures were established by chemical transformation. They exhibited weak cytotoxicity, but selective growth inhibition on panel screening using 39 human cancer cell lines.

Published
2015
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2. Determination of the Chemical Structures of Tandyukisins B–D, Isolated from a Marine Sponge-Derived Fungus

Author

Takashi Kikuchi, Maiko Kawashima, Yoshihide Umebayashi, Yuma Sugiura, Takeshi Yamada, and Reiko Tanaka

Subjects
Chemical transformation, Magnetic Resonance Spectroscopy, Trichoderma harzianum, Stereochemistry, Halichondria okadai, Pharmaceutical Science, Naphthalenes, Article, decalin, Cell Line, Tumor, Drug Discovery, Molecule, Animals, Humans, Cytotoxicity, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), marine microorganism, lcsh:QH301-705.5, Trichoderma, biology, Molecular Structure, Nuclear magnetic resonance spectroscopy, biology.organism_classification, Porifera, Sponge, lcsh:Biology (General), cytotoxicity, Two-dimensional nuclear magnetic resonance spectroscopy
Abstract

Tandyukisins B–D (1–3), novel decalin derivatives, have been isolated from a strain of Trichoderma harzianum OUPS-111D-4 originally derived from the marine sponge Halichondria okadai, and their structures have been elucidated on the basis of spectroscopic analyses using 1D and 2D NMR techniques. In addition, their chemical structures were established by chemical transformation. They exhibited weak cytotoxicity, but selective growth inhibition on panel screening using 39 human cancer cell lines.

Published
2015

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