Search

Your search keyword '"Yuhei Oyama"' showing total 4 results
Start Over Author "Yuhei Oyama"
4 results on '"Yuhei Oyama"'

1. Risk factors for clinical relapse in patients with ulcerative colitis who are in clinical remission but with endoscopic activity

Author

Ryosuke Horio, Jun Kato, Yuki Ohta, Takashi Taida, Keiko Saito, Miyuki Iwasaki, Yusuke Ozeki, Yushi Koshibu, Nobuaki Shu, Makoto Furuya, Yuhei Oyama, Hayato Nakazawa, Yukiyo Mamiya, Chihiro Goto, Satsuki Takahashi, Akane Kurosugi, Michiko Sonoda, Tatsuya Kaneko, Naoki Akizue, Kenichiro Okimoto, Tomoaki Matsumura, and Naoya Kato

Subjects
Mayo endoscopic score, treat to target, ulcerative colitis, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Background and Aim The treatment strategy for patients with ulcerative colitis (UC) in clinical remission who have not achieved mucosal healing is unclear. This study aimed to determine the risk factors of relapse in patients in clinical remission with endoscopic activity. Methods This retrospective, single‐center study included patients with UC who underwent colonoscopy (CS) and were in clinical remission with endoscopic activity. Characteristics were compared between patients who relapsed within 2 years after CS and those who did not. A Cox proportional hazards regression model was used to identify risk factors contributing to clinical relapse. Recent worsening in bowel symptoms was defined as increase in bowel frequency and/or increase in abdominal pain within approximately 1 month based on the descriptions in the medical charts. Results This study regarded 142 patients in clinical remission with an endoscopic activity of Mayo endoscopic subscore (MES) of ≥1 as eligible, and 33 (23%) patients relapsed during the observation period. Recent worsening of bowel symptoms was a significant risk factor for clinical relapse (hazard ratio [HR]: 3.02, 95% confidence interval [CI]: 1.34–6.84). This was particularly evident in patients with MES of 2 (HR: 5.16, 95% CI: 1.48–18.04), whereas no risk factors were identified in patients with MES of 1. The presence or absence of therapeutic intervention just after CS did not significantly affect clinical relapse. Conclusion Recent worsening in bowel symptoms was a significant risk factor for clinical relapse in patients with UC who were in clinical remission with endoscopic activity.

Published
2024
Full Text
View/download PDF

2. Hepatic encephalopathy due to cardiac cirrhosis

Author

Ryohei Ono, Hiroki Goto, Yuhei Oyama, Kazuya Tateishi, Hiroyuki Takaoka, Naoya Kato, and Yoshio Kobayashi

Subjects
cardiac cirrhosis, hepatic encephalopathy, portal hypertensive gastropathy, tricuspid regurgitation, Medicine, Medicine (General), R5-920
Abstract

Key Clinical Message Right‐sided heart failure, including tricuspid regurgitation (TR), can cause cardiac cirrhosis. The pathophysiology is reduced arterial perfusion and passive congestion secondary to increased systemic venous pressure. However, hepatic encephalopathy due to cardiac cirrhosis is rare. This is the first case of hepatic encephalopathy with cardiac cirrhosis caused by persistent TR.

Published
2023
Full Text
View/download PDF

3. Clinical Features Focusing on Extraintestinal Manifestations in Japanese Patients with Inflammatory Bowel Diseases: Far East 1000

Author

Yuki Ohta, Takashi Taida, Jun Kato, Sadahisa Ogasawara, Yuhei Oyama, Yukiyo Mamiya, Hayato Nakazawa, Ryosuke Horio, Chihiro Goto, Satsuki Takahashi, Akane Kurosugi, Michiko Sonoda, Wataru Shiratori, Tatsuya Kaneko, Yuya Yokoyama, Naoki Akizue, Hideaki Ishigami, Hirotaka Koseki, Kenichiro Okimoto, Keiko Saito, Masaya Saito, Tomoaki Matsumura, Tomoo Nakagawa, Yoshio Masuya, Yoshihiro Fukuda, Yoshio Kitsukawa, Haruhisa Shimura, Toshio Tsuyuguchi, and Naoya Kato

Subjects
Gastroenterology
Abstract

Background: Patients with inflammatory bowel diseases (IBD) can develop extraintestinal manifestations (EIMs) during the disease course, which sometimes impact their quality of life. Objectives: This study aimed to clarify the prevalence and types of EIMs using a hospital-based IBD cohort in Japan. Methods: A patient cohort with IBD was established in 2019, as participated by 15 hospitals in Chiba Prefecture of Japan. Using this cohort, the prevalence and types of EIMs, which are defined based on previous reports and the Japanese guidelines, were investigated. Results: This cohort enrolled 728 patients, including 542 ulcerative colitis (UC) and 186 Crohn’s disease (CD). Of these patients with IBD, 10.0% were identified with one or more EIMs (57 (10.5%) with UC and 16 (8.6%) with CD). Arthropathy and arthritis were the most common EIM in 23 (4.2%) patients with UC, followed by primary sclerosing cholangitis (PSC) (2.6%). Arthropathy and arthritis were also the most common in patients with CD, but no cases of PSC were observed. EIMs were more frequently observed in patients with IBD treated by specialists than in those treated by non-specialists (12.7% vs. 5.5%, p = 0.011). The incidence of EIMs in patients with IBD was not significantly different over time. Conclusions: The prevalence and types of EIMs in our hospital-based cohort in Japan did not significantly differ from those reported in previous or Western studies. However, the incidence might be underestimated due to the limited ability of non-IBD specialists to discover and describe EIMs in patients with IBD.

Published
2023

4. Efficacy of early clip-with-line method for colorectal endoscopic submucosal dissection

Author

Katsunobu Tawada, Shinichi Tazawa, Hiromasa Nomoto, Kazuhiko Kita, Yuhei Oyama, Hideyuki Takashiro, Masatoshi Usui, and Hirofumi Saito

Subjects
endocrine system, medicine.medical_specialty, Endoscopic Mucosal Resection, Perforation (oil well), Sodium hyaluronate, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Traction, Internal medicine, medicine, Humans, Stage (cooking), Adverse effect, Retrospective Studies, business.industry, Significant difference, Endoscopic submucosal dissection, Hepatology, Surgical Instruments, Surgery, Treatment Outcome, chemistry, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, business, Colorectal Neoplasms, Abdominal surgery
Abstract

Colorectal endoscopic submucosal dissection (ESD) remains demanding due to technical difficulties and high risk of perforation. Most of the reported traction methods are initiated after creating a mucosal flap, which is time consuming. To obtain a good visualization at the mucosal incision stage, we developed the early clip-with-line (ECL) method. This method was started immediately after injection of sodium hyaluronate solution into the submucosal layer. In this study, we evaluated the efficacy and the safety of the ECL method for colorectal ESD. We retrospectively analyzed all cases of colorectal ESDs (41 cases in total) performed from January 2017 to February 2019 in our institution. From January 2017 to August 2018, 27 of these cases were performed using conventional (non-ECL) ESDs, while from September 2018 onwards, the remaining 14 cases were performed using the ECL method. Retrospective comparison between the ECL group and the non-ECL group was conducted in terms of clinical characteristics, treatment outcomes, and adverse events. There were no significant differences in clinical characteristics between two groups. Procedure time (median [range]) was significantly shorter in the ECL group than in the non-ECL group (66 [29–131] min vs 90 [30–410] min; P = 0.03). As for adverse events, no case of perforation occurred in the ECL group, whereas perforation was observed in 7.4% (2/27) cases in the non-ECL group (no significant difference). Early clip-with-line method for colorectal endoscopic submucosal dissection reduced procedure time.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results