1. The intestinal delivery systems of ferulic acid: Absorption, metabolism, influencing factors, and potential applications
- Author
-
Yushan Chen, Wendi Teng, Jinpeng Wang, Ying Wang, Yuemei Zhang, and Jinxuan Cao
- Subjects
bioavailability ,delivery system ,ferulic acid ,gut microbiota ,intestinal barrier ,Nutrition. Foods and food supply ,TX341-641 ,Food processing and manufacture ,TP368-456 - Abstract
Abstract Ferulic acid (FA) is a hydroxycinnamic acid known for its strong antioxidant activity and potential benefits for intestinal health. However, its poor water solubility and instability limit its effectiveness. To address these issues, different ways have been explored to protect FA against degradation and further exert its potential benefits. This review discusses the absorption and metabolism of FA in the gut, as well as its potential impact on intestinal health. It also compares different intestinal delivery systems, such as nanoparticles, electrospun nanofibers, microcapsules, cross‐linked polymer gels, and Pickering emulsions, which can improve the solubility, stability, and bioavailability of FA in the gastrointestinal tract. This comprehensive review provides valuable insights for using FA in food, pharmaceutical, and nutraceuticals products.
- Published
- 2024
- Full Text
- View/download PDF