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To estimate the association between central retinal artery occlusion (CRAO) and major adverse cardiovascular and cerebrovascular events (MACCE), including their clinical characteristics, blood markers, and the contribution of CRAO to MACCE, as well as to assess any sex differences. This retrospective cohort study included continuous new-onset CRAO patients and 1:4controls during the same period. Correlations of CRAOwith the incidence of MACCE during follow-up and the sex-related differences were studied. One hundred and twenty-four CRAO patients and four hundred and ninety-six controls were enrolled. Neutrophil-to-lymphocyte ratio (NLR, P = 0.014) and high-sensitivity C-reactive protein (hs-CRP, P = 0.038) were tended to be higher in CRAO patients. After the follow-up period, 78 patients experienced MACCE. Multivariate Cox regression analysis showed that CRAO was a predictor of the occurrence of MACCE (HR: 2.321, 95% CI: 1.439 - 3.744, P = 0.001). Sex subgroups indicated that age, diabetes, current smoking, CRAO, NLR and hs-CRP increased the risk factor of MACCE in males (All P

The pandemic of coronavirus disease 2019 (COVID-19) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still underway. Due to the growing development of severe symptoms, it is necessary to promote effective therapies. Ambroxol [2-amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl) benzylamine] has long been used as one of the over-the-counter mucolytic agents to treat various respiratory diseases. Therefore, we focused on the mechanism of action of ambroxol in COVID-19 treatment. In vitro and in silico screening revealed that ambroxol may impede cell entry of SARS-CoV-2 by binding to neuropilin-1. Ambroxol could also interact with multiple inflammatory factors and signaling pathways, especially nuclear factor kappa B (NF-κB), to interfere cytokines cascade activated by SARS-CoV-2 internalization. Furthermore, multipathways and proteins, such as the cell cycle and matrix metalloproteinases (MMPs), were identified as significant ambroxol-targeting pathways or molecules in PBMC and lung of severe COVID-19 patients by bioinformatics analysis. Collectively, these results suggested that ambroxol may serve as a promising therapeutic candidate for the treatment of severe SARS-CoV-2 infection.

To evaluate and compare the blood lipid profile in retinal artery occlusion (RAO) and retinal vein occlusion (RVO). We included 82 RAO patients and 95 RVO patients in this retrospective case–control study. Controls were matched to RAO or RVO patients at a 1:1 ratio, respectively. Associated lipid variates were analyzed in multivariable logistic regression models. LDL-C (OR = 1.69), non-HDL-C (OR = 1.87), and ApoB (OR = 11.72) individually significantly increased the risk of RAO. ApoA1 was associated with RVO (OR = 0.02), and with 75.8% sensitivity and 67.4% specificity. TG (OR = 1.61), LDL-C (OR = 1.69), non-HDL-C (OR = 1.91), and ApoB (OR = 12.12) each significantly increased the risk of RAO when compared with RVO. ApoB, non-HDL-C, and LDL-C may be potential biomarkers in RAO patients. Low ApoA1 is an independent risk factor for the development of RVO.

Combining fabrics with a poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) coating is the most promising method to fabricate wearable thermoelectric (TE) devices. However, the high modulus, low strain, and low TE performance of PEDOT:PSS coating lead to poor flexibility and low power generation efficiency. In this study, dimethyl sulfoxide (DMSO) and ionic liquids (ILs) were selected as a modifier to enhance the flexibility and TE performance of PEDOT:PSS. Different from the penetrating structure and coil conformation of pristine PEDOT:PSS coating, a flexible continuous ultrathin layer of PEDOT:PSS/DMSO/1-ethyl-3-methylimidazolium dicyanamide (P/D/ED) with a linear conformation forms on the surface of cotton yarn. The morphology and structure of PEDOT:PSS and P/D/ED coating were characterized by FESEM, XPS, and Raman spectroscopy. Compared with the pristine PEDOT:PSS film, the P/D/ED film shows significantly reduced modules and enhanced strain and bending stability. Moreover, the TE performance of P/D/ED-coated yarn is significantly enhanced with nearly half mass loading. Based on this, a large-area wearable TE fabric with enhanced flexibility and TE performance was prepared. The output power density is 136.1 mW/m2 at ΔT = 40.8 K, which is a typically high value compared with the former reported composite TE fabrics. This study provides a new way to synergistically enhance the flexibility and TE performance of composite yarn, and the prepared TE fabric has great potential as a wearable power source.

High efficiency and anti-pollution oil/water separation membrane has been widely explored and researched. There are a large number of hydroxyl groups on the surface of silica, which has good wettability and can be used for oil-water separation membranes. Hydrophilic silica nanostructures with different morphologies were synthesized by changing templates and contents of trimethylbenzene (TMB). Here, silica nanospheres with radical pores, hollow silica nanospheres and worm-like silica nanotubes were separately sprayed on the PVA-co-PE nanofiber membrane (PM). The abundance of hydroxyl groups and porous structures on PM surfaces enabled the absorption of silica nanospheres through hydrogen bonds. Compared with different silica nanostructures, it was found that the silica/PM exhibited excellent super-hydrophilicity in air and underwater “oil-hating” properties. The PM was mass-produced in our lab through melt-extrusion-phase-separation technique. Therefore, the obtained membranes not only have excellent underwater superoleophobicity but also have a low-cost production. The prepared silica/PM composites were used to separate n-hexane/water, silicone oil/water and peanut oil water mixtures via filtration. As a result, they all exhibited efficient separation of oil/water mixture through gravity-driven filtration.

Precise adjustment of microstructure and handedness of chiral nanomaterials is important to regulate their properties and performance. Herein, helical 3-aminophenol formaldehyde resin (APF) nanotubes and corresponding carbonaceous nanotubes with controllable handedness and optical activity were obtained via an external metal ion-mediated supramolecular co-templating method in an enantiomerically pure template system, in which an appropriate amount of Mn2+ (Co2+ or Ni2+ ) with moderate coordination abilities can reverse the spatial arrangement of the phenylglycine-based amphiphilic template molecules through metal coordination. Different stacking modes of coordination complexes in disparate metal ion systems lead to diverse helical senses (diameter and pitch) of the obtained helical APF. In addition, this coordination mode of metal intervention can be applied to other amine-based helical polymer synthesis systems, which paves the way for the design of high-quality chiral nanomaterials with satisfactory physical parameters and properties.

Fabric-based piezoresistive sensors have demonstrated great potential in human motion and health detection applications. However, the conductive polymers of sensing units are easily influenced by high humidity and sweat conditions, which result in real-time electrical resistance fluctuation, and ultimately sensing inaccuracy. Herein, a hydrophobic, non-fluoride, titanium dioxide nanoparticle (TiO2-ODI)-modified fabric-based piezoresistive sensor was firstly employed to obtain accurate pressure sensing by prohibiting the interference from both high humidity and droplets in daily life. Due to the prominent isolation effect of the dense TiO2-ODI nanoparticle layer, for the first time, the dynamic normalized electrical resistance changes in a fabric-based piezoresistive sensor were negligibly influenced by high humidity of 95% and droplets of water, saline, milk, and sweat. Compared with the original pressure sensor (S = 0.85 kPa−1), the introduction of TiO2-ODI almost did not sacrifice the sensing performance (S = 0.83 kPa−1) and displayed prominent resistance to sweat interference. Thus, the hydrophobic TiO2-ODI pressure sensor exhibits promising potential and wide applicability for preparing highly accurate fabric structural piezoresistive sensors with wearing comfort, large area, self-cleaning property, ultraviolet protection, and anti-interference of high humidity and sweaty conditions, such as accurately evaluating human motion during exercise or on a rainy day.

Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide and has a poor prognosis. Pyroptosis, which is programmed cell necrosis mediated by gasdermin, participates in the progression of tumors. Recently, multiple omics analysis has been applied frequently to provide comprehensive and more precise conclusions. However, multiomics analysis combining pyroptosis-related signatures in HCC and their correlations with prognosis remain unclear. Here, we identified 42 pyroptosis genes that were differentially expressed between HCC and normal hepatocellular tissues. According to these differentially expressed genes (DEGs), all HCC cases could be divided into two heterogeneous subtypes. Then, we evaluated the prognostic value of differential pyroptosis-related genes to construct a multigene model using The Cancer Genome Atlas (TCGA) cohort. A 22-gene model was built and classified HCC patients in the TCGA cohort into low-risk and high-risk groups by the least absolute shrinkage and selection operator (LASSO) Cox regression method. HCC patients belonging to the low-risk group had significantly higher survival possibilities than those belonging to the high-risk group (p

CoS2 nanooctahedrons homogeneously encapsulated by hierarchical porous-reduced graphene oxide and polypyrrole thin film are constructed via a simple hydrothermal route, followed by vapor polymerization reaction. Owing to the porous conductive network and robust structural integrity characteristics, the optimal CoS2@RGO@PPy aerogel can not only facilitate electron and ion transfer but also shorten diffusion length and alleviate strain stress, ensuring superior sodium storage in terms of high capacity, excellent rate capability, and cycling stability. With a CoS2 content of 54.9%, CoS2@RGO@PPy electrode delivers a discharge capacity of 744 mAh g−1 at the current density of 0.1 A g−1. Moreover, it yields a reversible capacity of 554 mAh g−1 at 2.0 A g−1, higher than that of 495 mAh g−1 for CoS2@RGO electrode. The superior rate capability can be attributed to the favored surface capacitive behavior. And a combined contribution of diffusion-controlled and capacitive-induced process are derived. Furthermore, CoS2@RGO@PPy electrode maintains 348 mAh g−1 over a long period of 700 cycles at a high current density of 3 A g−1 and a capacity retention of 65.8%. The strategy can be extended to tailor the electrode structures for high-performance sodium-ion batteries.

Transcription factor DP family member 3 (TFDP3) is a cancer-testis antigen, mainly expressed in normal testis and multiple cancers.TFDP3gene (Gene ID: 51270) is located on the chromosome X and shares a high degree of sequence homology with TFDP1 and TFDP2, which can form heterodimers with E2F family members and enhance DNA-binding activity of E2Fs. In contrast to TFDP1 and TFDP2, TFDP3 downregulates E2F-mediated transcriptional activation. During DNA damage response in cancer cells, TFDP3 is induced and can inhibit E2F1-mediated apoptosis. Moreover, TFDP3 is involved in cell autophagy and epithelial-mesenchymal transition. Regarding cancer therapy opportunity, the transduction of dendritic cells with recombinant adenovirus-encoding TFDP3 can activate autologous cytotoxic T lymphocytes to target hepatoma cells. Here, we review the characterization of TFDP3, with an emphasis on the biological function and molecular mechanism. A better understanding of TFDP3 will provide new insights into the pathological mechanisms and therapeutic strategies for cancers.

Electronic skins have attracted increasing attentions due to their potential applications in skin prosthetics, humanoid robotics and wearable health monitoring. Along with the development of E-skin, safety, health and comfort have become essential elements that may affect the practical applications. In this study, a highly stretchable, hydrophobic polyolefin elastomer (POE) nanofiber membrane (NM) was prepared. The three dimensional porous structure of POE NM endows it good breathability, allowing the air and water vapor to permeate through it. Moreover, the POE NM is transparent to IR radiation, as a result the body heat could be dissipated through it, realizing the thermoregulatory property. The good breathability and thermoregulation of E-skin will help to create a safe, healthy and comfortable microenvironment for people by preventing overheat, stuffiness and inflammation. Then, a real functional and biomimetic strain sensor based on Ag@POE NM was prepared to monitor the human physiology and movement. The low detection limit (0.05%), fast response time (10 ms) and superior sensitivity (3953, 30%) indicate the potentially promising applications of POE NM based E-skin as wearable electronics. It is the first time that the concept of thermoregulation is introduced into the E-skin, pointing out a new direction for the development of wearable electronic devices.

Organic electrochemical transistors are flexible in design with characteristics such as miniaturisation, biocompatibility and amplification and are one of the rapidly developing research topics in recent years. As an excellent flexible material, fibre has unparalleled advantages in weaving and compatibility with the human body. Combining fibres with organic electrochemical transistors is a promising research direction that has the high sensitivity of organic electrochemical transistor testing and the human body compatibility and flexibility of wearable electronic products. This paper introduces the relevant operating principles, working modes and commonly used channel materials of organic electrochemical transistors. Based on the basic device structure of organic electrochemical transistors, the development and changes of organic electrochemical transistors in recent years are discussed, and the research results of fibre-based electrochemical transistors by researchers focusing on the application of fibre-based organic electrochemical transistors in chemical sensing, bio-sensing and other application explorations are summarized. Finally, this paper visioned the future development trend of fibre-based organic electrochemical transistors.

The rapid development of wearable devices puts forward higher requirements for mass-produced integrated smart systems that incorporate multiple electric components, such as energy supplying, multisensing, and communicating. To synchronously realize continuously self-powering, multifunctional sensing, distinguish signals from different stimuli, and productively design and fabricate a large-area sensing array, an all-fabric-based self-powered pressure-temperature-sensing electronic skin (e-skin) was prepared in this study by assembling highly flexible and compressible 3D spacer fabric (SF) and the thermoelectric poly(3,4-ethylenedioxythiophene)poly(styrenesulfonate) (PEDOT:PSS). The all-fabric-based e-skin can efficiently and accurately sense the temperature with a detection resolution of 0.1 K and a response time of 1 s, as well as pressure within a wide range of 200 Pa to 200 kPa and a fast response time of 80 ms. The electricity necessary for driving the sensor can be provided by the temperature difference between the body and environment. Notably, independent voltage and current signals can be generated and read out under the simultaneous temperature-pressure stimuli. For the first time, a real waistcoat-like e-skin with electricity-generating and pressure-temperature-sensing functions on the whole area was designed and prepared by a simple and easy to scale-up production method. All of these features make the developed all-fabric self-powered sensor have very promising applications.

Multi-walled carbon nanotubes (MWCNT) play a synergistic role with conducting polymer in practical applications such as biological sensing. In this paper, multi-walled carbon nanotube and polypyrrole (PPy) composites were prepared on a fiber surface for the first time, and their morphology and electrical properties were characterized. Compared with PPy-coated fiber, the presence of carbon nanotubes induced the growth of large areas of PPy nanowires. In addition, fiber organic electrochemical transistors (FECTs) based on PPy and MWCNT were assembled, showing a higher on/off ratio, better stability, and greater flexibility. The lactate biosensor based on FECTs exhibits high sensitivity, with a correlation coefficient of R = 0.9889, quick response time of 0.6-0.8 s, a wide linear response range of 1 nM-1 mM, and excellent selectivity for lactate. Furthermore, the lactate concentration in human sweat was successfully detected by a FECT-based sensor. The hybrid fibers can be easily woven and placed on fabric simply by stitching. This favorable performance of the FECT-based sensor makes it suitable for noninvasive sensing of lactate. Therefore, it provides a promising platform for future use in healthcare and detection applications. Graphical abstract.

In this study, poly(3,4-ethylenedioxythiophene) (PEDOT) nanocluster structure was synthesized on the reduced graphene oxide (rGO) modified cotton fibers. The organic electrochemical transistors based on the modified fiber have been assembled and their performance of different gate electrode transistors have been investigated. The transistor exhibits an excellent transconductance of up to 15.5 mS and a high on-off ratio close to 2*102. The bending angle and bending times have little effect on the device performance. The uric acid (UA) sensor based transistor has been fabricated for the first time. Flexible sensors based on molecularly imprinted polymer membrane (MIP) with different fiber gate electrodes have been investigated. The UA sensor with MIP/PEDOT/carbon fiber as the gate electrode has a sensitivity of 100 μA per decade from 1 nM to 500 μM, a linear coefficient of 0.97143, excellent selectivity, and good reproducibility. In addition, fiber based organic electrochemical transistors (FECTs) can be sewn into the fabric for monitoring and have successfully evaluated the detection of UA in artificial urine sample, with data consistent well with the UA concentration obtained from single fiber. Therefore, the sensor based FECTs can be used for low cost, accurate, non-enzymatic detection of UA in clinical diagnostics and bioanalytical applications.

Graphene oxide (GO)-induced porous coral-like polypyrrole have been fabricated via facile in situ polymerization. The morphologies and structures of PPy with different GO concentration were investigated by scanning electron microscopy and Fourier transform infrared spectroscopy. The results revealed that PPy/GO presented different morphologies and properties with varied amounts of GO. The electrochemical performances of prepared PPy/GO and PPy electrodes were compared. Notably, the PPy/GO electrodes showed much better electrochemical performance than the PPy electrodes. It indicated that the doping of GO in the composites significantly enhanced the electrochemical behaviors of PPy/GO electrodes. The excellent performance was the result of synergistic effects of GO and PPy structure and property. The device obtained a large specific capacitance of 568.35 F g−1 at a current density of 0.1 A/g and high energy density of 37.4 Wh kg−1. In addition, it also exhibited good cycle stability, with a capacitance retention rate of 83.4% for 500 cycles. More importantly, the electrode presented high flexibility property. The supercapacitor device fabricated is promising for the use in lightweight and flexible electronic devices.

Microsized cobalt sulfide is prepared via a solvothermal method in ethylenediamine solution by using CoCl2·6H2O as cobalt resource and thioacetamide as the sulfiding reagent. By varying the reaction parameters, CoS-24 and CoS-48 are obtained at 180 °C for 24 h and 48 h, respectively. Scanning electron microscopy and transmission electron microscopy images reveal that the microstructures are both assembled by nanosheets with width in the range of 130–160 nm and thickness of 30–50 nm. When used in SIBs, the more dispersed CoS-48 electrode exhibits superior sodium storage performances than that of CoS-24. For CoS-48, a specific capacity of 753 mAh g−1 is delivered at the current density of 100 mA g−1 in the potential window of 0.1–3.0 V. Moreover, 392 mAh g−1 can still be maintained at the current density of 1000 mA g−1 after 200 cycles, corresponding to 80% retention. These results demonstrate the potential of the carbon-free cobalt sulfide as high performance anode materials for energy storage.

Mesoporous polymeric aerogels with high compressibility and durability have attracted great attention due to their environmentally sustainable applications. However, it is still challenging to develop polymeric aerogels in a simple, low-cost and mass produced way. Herein, we report a strategy to prepare a high porosity polymeric nanofibrous aerogel (referred to as NFA) by direct freeze-drying of the poly(vinyl alcohol-co-ethylene) (PVA-co-PE) nanofibrous suspension. It is noteworthy that this process is free of gelation and any solvent exchange. In addition, the PVA-co-PE nanofibers were mass-produced from our production line, based on a high throughput Melt-Extrusion-Phase-Separation technique. Additionally, the network of the NFA aerogels can be tuned by the host–guest assembly of the nanofibers and the foreign PVA nano-lamellae from disordered/ordered cellular to a leaf-like structure. Further modification of the NFA by gaseous methyltrichlorosilane (MTS) led to covalently bonded siloxane nanoparticles formed on the surface, thereby facilely realizing the nanofibrous aerogel from hydrophilic to hydrophobic as well as achieving excellent resilience. The corresponding hydrophobic aerogel (designated as HNFA) possessed a slightly larger density of 11.1 mg cm−3 with an almost unchanged porosity of 99% and meso–macroporous pores of 5–100 nm compared with the NFA (8.3 mg cm−3). They are demonstrated as good thermal insulators (0.033–0.044 W m−1 K−1), high-performance air filters (99.2% filtration efficiency with 64 Pa pressure drop), organic pollutants absorbers (2500–5329% weight gain) and continuous water/oil separators. Therefore, this study opens up a new approach for simple and large-scale preparation of polymeric aerogels for versatile applications.

We report that poly(vinyl alcohol-co-ethylene) (PVA-co-PE) nanofibrous membrane was surface functionalized by iminodiacetic acid (IDA) and then chelated by Ni(II) ions for hemoglobin adsorption. The results indicated that bovine hemoglobin (BHb) adsorption on Ni(II)-chelated PVA-co-PE nanofibrous membrane was better described by the Langmuir model. The experimental maximum adsorption capacity value was 66 mg g−1. The method performed in this study provides an exploratory research for the large-scale purification of BHb and other proteins.

Nosocomial cross infection (NCI) seriously threatens human health, causing enormous economic loss. There is a critical need for new healthcare textiles to prevent NCI. Herein, a polymer modified nanoscale porous membrane was prepared by surface graft polymerization. The membrane had excellent antibacterial activity, and the antibacterial activity could be recharged through a simple method. And the membrane had a high filtration rate against bacteria. Excellent antibacterial activity and a high filtration rate mean the membrane could protect users from direct and indirect contact with pathogens, preventing the spread of diseases with the aid of textiles. The successful preparation of an anti-NCI membrane also provides a universal method for exploring nanoscale porous membrane materials as healthcare textiles to block NCI in hospitals.

Constructing carbon-based metal sulfides hybrids are efficient strategy for improving the sodium storage performance. And novel carbon materials are attractive in the development of electrodes. Herein, chiral amphiphiles are utilized to design chiral (C-CNTs) and straight (S-CNTs) nitrogen-doped CNTs through polycondensation and supramolecular assemble process, followed by pyrolysis. Besides, the CNTs can serve as skeleton, and MoS2 nanosheets are then anchored on the mesoporous CNTs matrix by hydrothermal reaction. Well-aligned architectures are obtained for MoS2/S-CNTs, while MoS2/C-CNTs are porous with short tubular morphology. As anode materials, MoS2/C-CNTs electrode outperforms the MoS2/S-CNTs counterparts and exhibits superior cycle stability and rate performances. It delivers a capacity of 368.8 mA h g−1 after 300 cycles at a high current density of 2 A g−1. Based on kinetics analysis, the percentage of capacitive charge storage is around 93.6% at the scan rate of 2 mV s−1. The phenomenon can be elucidated by the fast charge transfer resistance and small Warburg coefficient of MoS2/C-CNTs, which are superior to MoS2/S-CNTs. Therefore, the unique chiral structure combines the merits of expanded layer-spacing, nitrogen doping with high conductivity, and mesoporous channels, ensuring fast ion diffusion and pseudocapacitive behavior. This work provides an opportunity for fabricating other metal sulfides/C-CNTs SIBs anode materials with excellent cycling stability.

In this study, the pressure sensor of polypyrrole/cellulose (PPy/C) sponge with outstanding electrical conductivity , elasticity and flexibility was prepared by a simple and environmentally friendly method. The original cellulose sponge was obtained by freeze-drying of cellulose/NaOH/urea solution under an optimum condition. To get a conductive sponge, the pyrroles have been in-situ chemical oxidative polymerized on cellulose sponge. The effects of bath ratio and reaction time on the structures, morphologies and electrical resistances of PPy/C composite sponges were analyzed to decide the optimum process parameters. Moreover, a test device consisted of pressure meter and ohmmeter was designed to investigate the properties of the PPy/C sponge sensor. It exhibited the excellent conductivity, sensitivity under a very small pressure (0–5 kPa) and good repeatability. The results demonstrated that the PPy/C sponge could be a promising candidate for pressure sensor to test external stimulus.

Harvesting energy directly from the body heat has been suggested as an effective way to realize sustainably and uninterruptedly wearable power supply. However, the low temperature gradient (ΔT) between the human body and the environment has limited the power generation efficiency. In this study, the photothermal-thermoelectric 3D spacer fabric (ZrC-PPSF) was prepared by coating a thin zirconium carbide/polyurethane (ZrC/PU) photo-thermal layer on the poly (3,4-ethylenedioxythiophene):poly (styrenesulfonate) (PEDOT:PSS)/spacer fabric (SF) thermoelectric composite (PPSF). By utilizing the excellent photo-thermal conversion of ZrC and the thermal insulation performance of PPSF, a larger ΔT was generated and maintained, so as to enhance the power generated and efficiency. The effects of ZrC concentration, SF thickness and optical power density on the photo-thermal efficiency and voltage generated were studied. When the ZrC concentraiton is 1.5 wt%, the ΔT increases form 67.5 °C to 179.3 °C under the optical power density of 500 mW/cm2. Regardless of sunny and cloudy day, a larger ΔT can be generated. Based on this, a flexible and wearable wristband containing 30 ZrC-PPSF units was prepared. Encouragingly, the voltage generated by the wristband under the sunshine is almost 11 times the voltage generated indoors. Under the optical density of 100 mW/cm2 for 800 min, the highest voltage generated by the wristband is 9.11 mV, much higher than the 3.12 mV generated without light. All the results demonstrate that it is a very effective and simple method to improve the thermoelectric power generation efficiency by photo-thermal conversion. The wearable TE device prepared in this study is especially suitable for outdoor application, and provide continuous and stable energy for the wearable electronics.

In present work, polypyrrole (PPy) has been in-situ polymerized on a poly(vinyl alcohol- co -ethylene) (PVA- co -PE) nanofirous textile to form a 3D interconnecting PPy nanowires/nanofibrous textile composite electrode (designated as NW-PPy/NFs/PET). It demonstrates that the introduction of anthraquinone-2-sulfonic acid sodium (AQS) can tune the morphology of PPy from nanospheres to nanowires. The resulting PPy@PVA- co -PE conformal nanofibers act as bridges among intertwined PPy@PET fibers and PPy nanowires, leading to continuous pathways for ion/electron transfer and larger surface area for faradic reaction. Benefiting from this unique structure, the two-electrode supercapacitor using NaCl solution as electrolyte delivers a high power density of 800 W kg −1 at an energy density of 20 W h kg −1 per mass of active materials. Furthermore, the symmetric all-solid-state NW-PPy/NFs/PET supercapacitor demonstrates high flexibility and cycle stability. Therefore, this work may open a new way to develop light weight and cost-effective electrodes for flexible energy storage devices.

Polyaniline (PANI) has been fabricated on three-dimensional polyethyleneterephthalate (PET) coated with poly(vinyl alcohol-co-ethylene) nanofibers (NFs) substrate through a facile in-situ chemical oxidative polymerization method. With various concentrations of NFs, a series of PANI/NFs/PET-x flexible electrodes have been successfully obtained. Among them, the PANI/NFs/PET-5.4 (NFs mass loading of 5.4 g m−2) electrode displays the highest conductivity of 0.75 S cm−1, and the largest areal capacitance of 1.47 F cm−2 (503 F g−1) at 1 mV s−1or 1.58 F cm−2 (543 F g−1) at 1.0 mA cm−2. Furthermore, symmetric supercapacitor is assembled, exhibiting high power density (20.11 W m−2), energy density (0.61 Wh m−2) and cycling stability. This can be ascribed to the NFs, which not only provides high conductivity for electron transport, but also mitigates the degradation of PANI through the synergistic effect between NFs and PANI.