Search

Your search keyword '"Yuan, Zi-Guo"' showing total 231 results
Start Over Author "Yuan, Zi-Guo"
231 results on '"Yuan, Zi-Guo"'

8. The Genetic Diversity and Interspecific Transmission of Circovirus in Rhizomys sinensis in Guangdong, Southern China

Author

Ren, Zhaowen, primary, Yuan, Zi-Guo, additional, Luo, Shengjun, additional, Sun, Chenglong, additional, Zhang, Pian, additional, Yu, Jieshi, additional, Chen, Xiaofan, additional, Chen, Jinping, additional, Hua, Yan, additional, Wang, Gang, additional, Xiang, Hua, additional, Cai, Rujian, additional, Chen, Jing, additional, Huang, Yuan, additional, Yuan, Hao, additional, Li, Na, additional, Wang, Xiaohu, additional, and Liao, Ming, additional

Published
2023
Full Text
View/download PDF

9. Pseudorabies gD protein protects mice and piglets against lethal doses of pseudorabies virus

Author

Zhao, Mengpo, primary, Chen, Jing, additional, Luo, Shengjun, additional, Yan, Renhe, additional, Zhang, Pian, additional, Ren, Zhaowen, additional, Chen, Xiaofan, additional, Wang, Gang, additional, Xiang, Hua, additional, Cai, Rujian, additional, Huang, Yuan, additional, Li, Na, additional, Li, Hongwei, additional, Yuan, Zi-Guo, additional, and Wang, Xiaohu, additional

Published
2023
Full Text
View/download PDF

15. SARS-CoV-2: An Updated Review Highlighting Its Evolution and Treatments

Author

Zhang, Xirui, primary, Yuan, Hao, additional, Yang, Zipeng, additional, Hu, Xiaoyu, additional, Mahmmod, Yasser S., additional, Zhu, Xiaojing, additional, Zhao, Cuiping, additional, Zhai, Jingbo, additional, Zhang, Xiu-Xiang, additional, Luo, Shengjun, additional, Wang, Xiao-Hu, additional, Xue, Mengzhou, additional, Zheng, Chunfu, additional, and Yuan, Zi-Guo, additional

Published
2022
Full Text
View/download PDF

30. Insight into the current Toxoplasma gondii DNA vaccine: a review article.

Author

Zhang, Xirui, Yuan, Hao, Mahmmod, Yasser S., Yang, Zipeng, Zhao, Mengpo, Song, Yining, Luo, Shengjun, Zhang, Xiu-Xiang, and Yuan, Zi-Guo

Subjects
DNA vaccines, TOXOPLASMA gondii, MOLECULAR interactions, PROBLEM solving, ANTIGENS, OOCYSTS
Abstract

Toxoplasma gondii (T.gondii) is a widespread protozoan with significant economic losses and public health importance. But so far, the protective effect of reported DNA-based vaccines fluctuates widely, and no study has demonstrated complete protection. This review provides an inclusive summary of T. gondii DNA vaccine antigens, adjuvants, and some other parameters. A total of 140 articles from 2000 to 2021 were collected from five databases. By contrasting the outcomes of acute and chronic challenges, we aimed to investigate and identify viable immunological strategies for optimum protection. Furthermore, we evaluated and discussed the impact of several parameters on challenge outcomes in the hopes of developing some recommendations to assist better future horizontal comparisons among research. In the coming five years of research, the exploration of vaccine cocktails combining invasion antigens and metabolic antigens with genetic adjuvants or novel DNA delivery methods may offer us desirable protection against this multiple stage of life parasite. In addition to finding a better immune strategy, developing better in silico prediction methods, solving problems posed by variables in practical applications, and gaining a more profound knowledge of T.gondii-host molecular interaction is also crucial towards a successful vaccine. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

40. Seroprevalence of Toxoplasma gondii infection in pet dogs in Lanzhou, Northwest China

Author

Zhou Dong-Hui, Yuan Zi-Guo, Chen Mu-Xin, Chen Jia-Xu, Liu Guang-Yuan, Fu Bao-Quan, Huang Si-Yang, Wu Song-Ming, Weng Ya-Biao, Zhu Xing-Quan, and Ye De-He

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background In recent years, surveys of Toxoplasma gondii infection in dogs have been reported worldwide, including China. However, little is known about the prevalence of T. gondii in pet dogs in Northwest China. In the present study, the prevalence of T. gondii in pet dogs in Lanzhou, China was investigated using the modified agglutination test (MAT). Results In this survey, antibodies to T. gondii were found in 28 of 259 (10.81%) pet dogs, with MAT titers of 1:20 in 14 dogs, 1:40 in nine, 1:80 in four, and 1:160 or higher in one dog. The prevalence ranged from 6.67% to 16.67% among dogs of different ages, with low rates in young pet dogs, and high rates in older pet dogs. The seroprevalence in dogs >3 years old was higher than that in dogs ≤1 years old, but the difference was not statistically significant (P >0.05). The seroprevalence in male dogs was 12.50% (17 of 136), and in female dogs it was 8.94% (11 of 123), but the difference was not statistically significant (P >0.05). Conclusions A high prevalence of T. gondii infection was found in pet dogs in Lanzhou, Northwest China, which has implications for public health in this region. In order to reduce the risk of exposure to T. gondii, further measures and essential control strategies should be carried out rationally in this region.

Published
2011
Full Text
View/download PDF

41. Identification and characterization of microRNAs in Clonorchis sinensis of human health significance

Author

Yuan Zi-Guo, Lin Rui-Qing, Yan Chao, Cai Xian-Quan, Nisbet Alasdair J, Liu Quan, Xu Min-Jun, Song Hui-Qun, He Xian-Hui, and Zhu Xing-Quan

Subjects
Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background Clonorchis sinensis is a zoonotic parasite causing clonorchiasis-associated human disease such as biliary calculi, cholecystitis, liver cirrhosis, and it is currently classified as carcinogenic to humans for cholangiocarcinoma. MicroRNAs (miRNAs) are non-coding, regulating small RNA molecules which are essential for the complex life cycles of parasites and are involved in parasitic infections. To identify and characterize miRNAs expressed in adult C. sinensis residing chronically in the biliary tract, we developed an integrative approach combining deep sequencing and bioinformatic predictions with stem-loop real-time PCR analysis. Results Here we report the use of this approach to identify and clone 6 new and 62,512 conserved C. sinensis miRNAs which belonged to 284 families. There was strong bias on families, family members and sequence nucleotides in C. sinensis. Uracil was the dominant nucleotide, particularly at positions 1, 14 and 22, which were located approximately at the beginning, middle and end of conserved miRNAs. There was no significant "seed region" at the first and ninth positions which were commonly found in human, animals and plants. Categorization of conserved miRNAs indicated that miRNAs of C. sinensis were still innovated and concentrated along three branches of the phylogenetic tree leading to bilaterians, insects and coelomates. There were two miRNA strategies in C. sinensis for its parasitic life: keeping a large category of miRNA families of different animals and keeping stringent conserved seed regions with high active innovation in other places of miRNAs mainly in the middle and the end, which were perfect for the parasite to perform its complex life style and for host changes. Conclusions The present study represented the first large scale characterization of C. sinensis miRNAs, which have implications for understanding the complex biology of this zoonotic parasite, as well as miRNA studies of other related species such as Opisthorchis viverrini and Opisthorchis felineus of human and animal health significance.

Published
2010
Full Text
View/download PDF

44. Recombinant canine adenovirus type-2 expressing TgROP16 provides partial protection against acute Toxoplasma gondii infection in mice

Author

Li, Xiu-zhen, primary, Lv, Lin, additional, Zhang, Xu, additional, Anchang, Kenneth Yongabi, additional, Abdullahi, Auwalu Yusuf, additional, Tu, Liqing, additional, Wang, Xiaohu, additional, Xia, Lijun, additional, Zhang, Xiu-Xiang, additional, Feng, Weili, additional, Lu, Chunxia, additional, Li, Shoujun, additional, and Yuan, Zi-Guo, additional

Published
2016
Full Text
View/download PDF

45. Plasmodium vivax seroprevalence in bred cynomolgus monkeys, China

Author

Li, Hai-Long, Liu, Zhen-Yong, Li, Juan, Ai, Lin, Zhou, Dong-Hui, Yuan, Zi-Guo, Lin, Rui-Qing, Weng, Ya-Biao, and Zhu, Xing-Quan

Subjects
Monkeys -- Health aspects, Parasitic diseases -- Health aspects, Malaria -- Health aspects, Health
Abstract

To the Editor: Malaria caused by Plasmodium spp. is one of the most prevalent parasitic diseases in the world, especially in tropical countries. P. vivax represents the second most prevalent [...]

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results