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Objective To analyze the research status and hotspots in nursing of integrated traditional Chinese and western medicine in the recent decade, and provide reference for further studies. Methods Relevant studies published in the databases of CNKI, Wanfang Data, VIP from Jan. 1st 2012 to October. 1st 2022 were searched for bibliometric analysis. A visualized analysis of author name, institution, key words and other issues was performed. Results Totally 1498 studies were included, and number of published articles reached its peak in 2015. The hotspots included Care of elderly patients with chronic diseases, psychology/emotion, Standardized nursing care and so on. Conclusion Studies about nursing of integrated traditional Chinese and western medicine are becoming more popular, and more efforts should be paid to improve the quality, breadth and depth of research. A productive and well-established relationship between institutions is foundation of multi-centered large-sample researches, promoting the innovations, highlighting the advantages of nursing of integrated traditional Chinese and western medicine, improving patients health outcomes and quality of life. (目的 对近十年有关中西医结合护理的研究现状、热点和趋势进行可视化分析, 为开展进一步研究提供参考。方法 检索中国知网(CNKI)、万方数据库(Wanfang Data)、维普中文科技期刊数据库(VIP)中2012年1月1日—2022年10月1日发表的相关文献进行计量学分析, 借助NoteExpress软件对作者、机构和关键词等内容进行可视化分析。结果 共纳入相关文献1498篇; 发文量在2015年达到高峰期; 研究热点集中在老年慢病护理、心理/情绪、规范护理模式等方面。结论 我国中西医结合护理的相关研究逐渐成为研究热点, 但研究的质量、广度和深度仍有待进一步提升; 各研究机构之间需加强协作, 开展多中心、大样本的研究, 着力推广创新发明成果, 凸显中西医结合护理的优势, 改善患者健康结局, 提高生活质量。)

Objective To investigate the care burden and its influencing factors in caregivers of patients with intracranial aneurysms. Methods The convenience sampling method was used to select 144 patients with intracranial aneurysms and their primary caregivers in the neurosurgery department as the research objects, and the caregivers were surveyed by Zrait Burden Scale (ZBI), Social Support Rating Scale (SSRS), Hospital Anxiety Depression Scale(HADS). Results The averaged score of ZBI was (39. 15±7. 61) , which was higher than the norm (P＜0. 01). The score of anxiety(10. 89±3. 16) and depression (11. 04±2. 97)was higher than the norm, respectively (P＜0. 01). The overall score of SSRS(26. 27±4. 23), subjective support(9. 46±2. 42), objective support(8. 99±2. 51)and social support availability(7. 81±1. 51)was higher than the norm, respectively (P＜0. 01). Age of patient, way of payment, surgical type and postoperative complications were associated with degree of care burdens(P＜0. 05). Conclusion Findings of the study indicated a varying degree of care burden among caregivers of patients with intracranial aneurysms. Attention should be paid on the mental health of caregivers, and efforts should be made to care-giving skills training, social and financial support, in order to improve the nursing quality and rehabilitation of patients. (目的 分析颅内动脉瘤患者照顾者照顾负担水平及其影响因素。方法 采用方便抽样法选取2021年5月—11月医院神经外科 144 名颅内动脉瘤患者及其主要照顾者为研究对象, 采用Zarit护理者负担量表(ZBI)、社会支持评定量表(SSRS)、医院焦虑抑郁量表(HAD)对照顾者进行调查。结果 照顾者ZBI量表得分平均(39. 15±7. 61)分, HAD量表中焦虑维度得分(10. 89±3. 16)分, 抑郁维度得分(11. 04±2. 97), 均高于常模(P＜0. 01); SSRS量表总分(26. 27±4. 23)分, 主观支持维度得分(9. 46±2. 42)分, 客观支持维度得分(8. 99±2. 51)分, 社会支持利用度维度得分(7. 81±1. 51)分, 均低于常模(P＜0. 01)。患者年龄、付费方式、手术方式和术后并发症对照顾负担有影响(P＜0. 05)。结论 颅内动脉瘤患者照顾者存在不同程度照顾负担。应关注照顾者心理状态, 通过开展技能培训, 完善社会支持和经济帮助, 减轻照顾者负担, 进而提升照护质量, 促进患者康复。)

Objective Methods 120 elderly patients suffering from aneurysmal subarachnoid hemorrhage and receiving craniotomy from June 2019 to June 2021 were enrolled. Patients were randomly and equally divided into two groups: the traditional group(n=60, who received traditional nursing model) and the ERAS group (n=60, who received ERAS-based sputum drainage nursing model). The expectoration volume, blood oxygen saturation and proinflammatory cytokine level between traditional group and ERAS group were compared. Results At 5th day after intervention, the daily expectoration volume ［(40. 51±9. 25) mL vs. (22. 52±4. 25) mL, P＜0. 01］ and blood oxygen saturation［(94. 52±4. 57)% vs. (84. 25±5. 11)%, P＜0. 01］in the ERAS group were better than those in the traditional group. The percentage of effective expectoration in the ERAS group was higher than that in the traditional group (91. 67% vs, 76. 67%, P＜0. 05). At 5th day after intervention, Patients receiving ERAS-based nursing model had a lower proinflammatory cytokine level (IL-1β, IL- and TNF-α)comparing with patients receiving traditional nursing model (P

This paper summarized the preoperative skin preparation and perioperative comprehensive nursing for a patient undergoing surgery for intracranial aneurysm. Based on the theory of enhanced recovery after surgery, the preoperative skin preparation was adopted. Perioperative comprehensive nursing interventions such as surgical positioning care, illness condition observation, incision management, catheter maintenance, dietary care, medication care, prevention of complications and health education were carried out to reduce the postoperative complications and improve the recovery of the patient. (本文总结1例颅内动脉瘤行手术治疗患者术前局部备皮方法和围手术期综合护理经验。通过配合快速康复外科处理, 给予患者局部备皮, 同时开展术前护理、体位护理、病情观察、切口护理、管路护理、饮食干预、用药指导、并发症护理以及健康指导等围手术期综合护理措施, 缓解患者不良情绪, 积极防治术后并发症, 促进术后恢复。)

In response to the precision machining of frictionless aluminum alloy cylinder with anodized oxide films, a composite spiral abrasive flow polishing method was proposed. A simulation model was established to analyze the collision between particles and the wall in polishing processes, and he influences of particle velocity in different directions on polishing were investigated. The processing mechanism of the composite spiral abrasive flow polishing was revealed. The simulation results show hat the composite spiral motion changes the trajectory of the abrasive particles, and the addition of rotational velocity enhances the effective stress of the abrasive. The effective plastic deformation of the wall increases with the spiral groove speed. Particle image velocimetry observation experimental results demonstrate that the composite spiral motion increases the rotational velocity of the abrasives and enhances the vorticity of the flow field. The experimental results show that the composite spiral abrasive flow polishing not only causes less damages to the aluminum alloy anodized film, and effectively improves the surface quality of the workpieces. [ABSTRACT FROM AUTHOR]

Fumonisin B1 (FB1) is a common environmental mycotoxin produced by molds such as Fusarium verticillioides. The toxin poses health risks to domestic animals, including pigs, through FB1‐contaminanted feed. However, the cytotoxicity of FB1 to porcine intestines has not been fully analyzed. In the present study, the effects of FB1 on oxidative stress and nutrient transporter‐associated genes of the porcine intestinal IPEC‐J2 cells were explored. FB1 decreased IPEC‐J2 proliferation but did not trigger reactive oxygen species (ROS) overproduction. Meanwhile, FB1 reduced the expression levels of the transporters l‐type amino acid transporter‐1 (y+LAT1), solute carrier family 7 member 1 (SLC7A1), solute carrier family 1 member 5 (ASCT2), and excitatory amino acid carrier 1 (EAAC1); in addition, FB1 reduced the levels of the fatty acid transporters long‐chain fatty acid transport protein 1 (FATP1) and long‐chain fatty acid transport protein 4 (FATP4) as well as glucose transporters Na+/glucose cotransporter 1 (SGLT1) and glucose transporter 2 (GLUT2). FB1 stimulation increased the expression levels of peptide transporter peptide transporter 1 (PepT1) and metal ion transport‐related gene zinc transporter 1 (ZNT1). Moreover, metal ion transporter divalent metal transporter 1 (DMT1) expression was depressed by a higher dosage of FB1. The data indicate that FB1 results in aberrant expression of nutrient transporters in IPEC‐J2 cells, thereby exerting its toxicity even though it fails to exert ROS‐dependent oxidative stress. [ABSTRACT FROM AUTHOR]