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33 results on '"Yuan, Mengchen"'

13. Coating Porous TiO2 Films on Carbon Nanotubes to Enhance the Durability of Ultrafine PtCo/CNT Nanocatalysts for the Oxygen Reduction Reaction

Author

Cao, Feng, primary, Zhang, Hongyu, additional, Duan, Xiao, additional, Li, Xiaoke, additional, Ding, Rui, additional, Hua, Kang, additional, Rui, Zhiyan, additional, Wu, Yongkang, additional, Yuan, Mengchen, additional, Wang, Jiankang, additional, Li, Jia, additional, Han, Min, additional, and Liu, Jianguo, additional

Published
2022
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18. Coating Porous TiO2Films on Carbon Nanotubes to Enhance the Durability of Ultrafine PtCo/CNT Nanocatalysts for the Oxygen Reduction Reaction

Author

Cao, Feng, Zhang, Hongyu, Duan, Xiao, Li, Xiaoke, Ding, Rui, Hua, Kang, Rui, Zhiyan, Wu, Yongkang, Yuan, Mengchen, Wang, Jiankang, Li, Jia, Han, Min, and Liu, Jianguo

Abstract

The development of excellent activity and durability catalysts for the oxygen reduction reaction (ORR) is essential for the commercialization of proton exchange membrane fuel cells (PEMFCs). Reducing the size of catalyst particles can provide more reaction sites to mitigate the performance degradation caused by reduced platinum loading. However, at the same time, it makes the particles more prone to agglomeration and exfoliation, leading to a rapid reduction in catalyst activity. Here, we present the design of a composite support (TiO2/CNT) with a porous TiO2film that immobilizes PtCo nanoparticles (NPs) loaded on the support while protecting the carbon nanotubes inside. The particle size of PtCo NPs was only 1.99 nm (determined by transmission electron microscopy), but the nanocatalyst (PtCo/TiO2/CNT) maintained high catalytic performance and stability on account of the strong metal support interaction (SMSI). PtCo/TiO2/CNT exhibited a high mass activity (MA, 0.476 A mgPt–1) and was found to have MA retention rates of 91.7 and 88.8% in durability tests performed at 0.6–1.0 V and 1.0–1.5 V, respectively.

Published
2022
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19. Oxidative Stress-Mediated Blood-Brain Barrier (BBB) Disruption in Neurological Diseases

Author

Song, Ke, Li, Yuanyuan, Zhang, Hanlai, An, Na, Wei, Yufei, Wang, Liqin, Tian, Chao, Yuan, Mengchen, Sun, Yikun, Xing, Yanwei, and Gao, Yonghong

Subjects
Article Subject
Abstract

The blood-brain barrier (BBB), as a crucial gate of brain-blood molecular exchange, is involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused by an imbalance between the production of reactive oxygen species (ROS) and the scavenger system. Since oxidative stress plays a significant role in the production and maintenance of the BBB, the cerebrovascular system is especially vulnerable to it. The pathways that initiate BBB dysfunction include, but are not limited to, mitochondrial dysfunction, excitotoxicity, iron metabolism, cytokines, pyroptosis, and necroptosis, all converging on the generation of ROS. Interestingly, ROS also provide common triggers that directly regulate BBB damage, parameters including tight junction (TJ) modifications, transporters, matrix metalloproteinase (MMP) activation, inflammatory responses, and autophagy. We will discuss the role of oxidative stress-mediated BBB disruption in neurological diseases, such as hemorrhagic stroke, ischemic stroke (IS), Alzheimer’s disease (AD), Parkinson’s disease (PD), traumatic brain injury (TBI), amyotrophic lateral sclerosis (ALS), and cerebral small vessel disease (CSVD). This review will also discuss the latest clinical evidence of potential biomarkers and antioxidant drugs towards oxidative stress in neurological diseases. A deeper understanding of how oxidative stress damages BBB may open up more therapeutic options for the treatment of neurological diseases.

Published
2020
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27. Mechanisms and Treatments of Oxidative Stress in Atrial Fibrillation

Author

Ren, Xiaomeng, primary, Wang, Xiaofeng, additional, Yuan, Mengchen, additional, Tian, Chao, additional, Li, Huilong, additional, Yang, Xinyu, additional, Li, Xinye, additional, Li, Yanda, additional, Yang, Yihan, additional, Liu, Nian, additional, Shang, Hongcai, additional, Gao, Yonghong, additional, and Xing, Yanwei, additional

Published
2018
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30. Anticancer Therapy-Induced Atrial Fibrillation: Electrophysiology and Related Mechanisms

Author

Yang, Xinyu, primary, Li, Xinye, additional, Yuan, Mengchen, additional, Tian, Chao, additional, Yang, Yihan, additional, Wang, Xiaofeng, additional, Zhang, Xiaoyu, additional, Sun, Yang, additional, He, Tianmai, additional, Han, Songjie, additional, Chen, Guang, additional, Liu, Nian, additional, Gao, Yonghong, additional, Hu, Dan, additional, Xing, Yanwei, additional, and Shang, Hongcai, additional

Published
2018
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31. Gender Differences in Prognosis and Risk Stratification of Brugada Syndrome: A Pooled Analysis of 4,140 Patients From 24 Clinical Trials

Author

Yuan, Mengchen, primary, Tian, Chao, additional, Li, Xinye, additional, Yang, Xinyu, additional, Wang, Xiaofeng, additional, Yang, Yihan, additional, Liu, Nian, additional, Kusano, Kengo F., additional, Barajas-Martinez, Hector, additional, Hu, Dan, additional, Shang, Hongcai, additional, Gao, Yonghong, additional, and Xing, Yanwei, additional

Published
2018
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32. Recent Patents of Micro-arc Oxidation Technology

Author

Yuan, Mengchen and Li, Zhaolong

Abstract

Micro-arc oxidation (MAO) is a new surface treatment technology that can improve wear resistance, corrosion resistance, high voltage insulation, and other metal properties. Therefore, this technology is widely used in automobile manufacturing, aerospace, ship anti-corrosion, medical equipment, sewage treatment, and other fields. This paper reviews the representative patents of micro-arc oxidation technology at home and abroad. The micro-arc oxidation processing device, the process method of micro-arc oxidation processing, the power supply and electrical parameters of micro-arc oxidation, the preparation of electrolytes, and the methods of anticorrosion and protection of metal surface are analyzed. The development trend of micro-arc oxidation technology in the future is discussed. Micro-arc oxidation is a simple, green, and environment- friendly surface treatment technology, and there will be more patents in the field of micro- arc oxidation in the future.

Published
2024
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33. Coating Porous TiO 2 Films on Carbon Nanotubes to Enhance the Durability of Ultrafine PtCo/CNT Nanocatalysts for the Oxygen Reduction Reaction.

Author

Cao F, Zhang H, Duan X, Li X, Ding R, Hua K, Rui Z, Wu Y, Yuan M, Wang J, Li J, Han M, and Liu J

Abstract

The development of excellent activity and durability catalysts for the oxygen reduction reaction (ORR) is essential for the commercialization of proton exchange membrane fuel cells (PEMFCs). Reducing the size of catalyst particles can provide more reaction sites to mitigate the performance degradation caused by reduced platinum loading. However, at the same time, it makes the particles more prone to agglomeration and exfoliation, leading to a rapid reduction in catalyst activity. Here, we present the design of a composite support (TiO 2 /CNT) with a porous TiO 2 film that immobilizes PtCo nanoparticles (NPs) loaded on the support while protecting the carbon nanotubes inside. The particle size of PtCo NPs was only 1.99 nm (determined by transmission electron microscopy), but the nanocatalyst (PtCo/TiO 2 /CNT) maintained high catalytic performance and stability on account of the strong metal support interaction (SMSI). PtCo/TiO 2 /CNT exhibited a high mass activity (MA, 0.476 A mg Pt -1 ) and was found to have MA retention rates of 91.7 and 88.8% in durability tests performed at 0.6-1.0 V and 1.0-1.5 V, respectively.

Published
2022
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