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Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer associated with a poor prognosis. ICC accounts for about 10% of primary liver malignancies but with increasing incidence in recent years. Recently, some studies suggested that minimally interventional therapy can be used in the treatment of ICC. However, there are few references on interventional therapy for the clinical treatment of ICC. Herein we reported a case of a 48-year-old man who suffered from ICC. The patient was diagnosed with ICC by computerized tomography scan and pathological biopsy. The patient was completely cured by minimally interventional therapy with iodine-125 seed implantation. These results provide an important reference for the treatment option of ICC.

The fuel consumption and greenhouse gas (GHG) emission patterns of taxis are in accordance with the urban structure and daily travel footprints of residents. With taxi trajectory data from the intelligent transportation system in Xi'an, China, this study excludes trajectories from electric taxis to accurately estimate GHG emissions of taxis. A gradient boosting decision tree (GBDT) model is employed to examine the nonlinear influence of the built environment (BE) on the GHG emissions of taxis on weekdays and weekends in various urban areas. The research findings indicate that the GHG emissions of taxis within the research area exhibit peak levels during the time intervals of 7:00–9:00, 12:00–14:00, and 23:00–0:00, with notably higher emission factors on weekends than on weekdays. Moreover, a clear nonlinear association exists between BE elements and GHG emissions, with a distinct impact threshold. In the different urban areas, the factors that influence emissions exhibit spatial and temporal heterogeneity. Metro/bus/taxi stops density, residential density, and road network density are the most influential BE elements impacting GHG emissions. Road network density has both positive and negative influences on the GHG emissions in various urban areas. Increasing the road network density in subcentral urban areas and increasing the mixed degree of urban functions in newly developed urban centers to 1.85 or higher can help reduce GHG emissions. These findings provide valuable insights for reducing emissions in urban transportation and promoting sustainable urban development by adjusting urban functional areas. [ABSTRACT FROM AUTHOR]

Existing studies have limited evidence about the complex nonlinear impact mechanism of road network topology and built environment on bike-sharing systems' greenhouse gas (GHG) emission reduction benefits. To fill this gap, we examine the nonlinear effects of road network topological attributes and built environment elements on the potential GHG emission reduction of dockless bike-sharing (DBS) trips in Shenzhen, China. Various methods are employed in the research framework of this study, including a GHG emission reduction estimation model, spatial design network analysis (sDNA), gradient boosting decision tree (GBDT), and partial dependence plots (PDPs). Results show that road network topological variables have the leading role in determining the potential GHG emission reduction of DBS trips, followed by land use variables and transit-related variables. Moreover, the nonlinear impacts of road network topological variables and built environment variables show certain threshold intervals for the potential GHG emission reduction of DBS trips. Furthermore, the impact of built environment on the potential GHG emission reduction of DBS trips is moderated by road network topological indicators (closeness and betweenness). Compared with betweenness, closeness has a greater moderating effect on built environment variables. These findings provide empirical evidence for guiding bike-sharing system planning, bike-sharing rebalancing strategy optimization, and low-carbon travel policy formulation. [ABSTRACT FROM AUTHOR]

From 2008 to 2021, this study analyzed the spatial correlation characteristics between provincial transportation carbon emission intensity and explored ways to reduce transportation carbon emissions. This study used the modified gravity model, social network analysis (SNA) method, and temporal exponential random graph model (TERGM) to analyze the spatial correlation network evolution characteristics and driving mechanism of China's transportation carbon emission intensity. This study found that China's transportation carbon emission intensity and spatial correlation network have unbalanced characteristics. The spatial correlation network of transportation carbon emission intensity revealed that Shanghai, Beijing, Tianjin, Guangdong, Fujian, and other provinces were at the center of the network, with significant intermediary effects. The spatial correlation of transportation carbon emission intensity was divided into four functional plates: "two-way spillover", "net benefit", "broker", and "net spillover". The "net benefit" plate was mainly located in developed regions, and the "net spillover" plate was primarily located in underdeveloped regions. Endogenous structural and exogenous mechanism variables were the main factors affecting the evolution of the spatial correlation network of provincial transportation carbon emission intensity. [ABSTRACT FROM AUTHOR]

This work proposes a framework for the optimization of postdisaster road network restoration strategies from a perspective of resilience. The network performance is evaluated by the total system travel time (TSTT). After the implementation of a postdisaster restoration schedule, the network flows in a certain period of days are on a disequilibrium state; thus, a link-based day-to-day traffic assignment model is employed to compute TSTT and simulate the traffic evolution. Two indicators are developed to assess the road network resilience, i.e., the resilience of performance loss and the resilience of recovery rapidity. The former is calculated based on TSTT, and the latter is computed according to the restoration makespan. Then, we formulate the restoration optimization problem as a resilience-based bi-objective mixed integer programming model aiming to maximize the network resilience. Due to the NP-hardness of the model, a genetic algorithm is developed to solve the model. Finally, a case study is conducted to demonstrate the effectiveness of the proposed method. The effects of key parameters including the number of work crews, travelers' sensitivity to travel time, availability of budget, and decision makers' preference on the values of the two objectives are investigated as well., Author(s): Xinhua Mao [1]; Jibiao Zhou (corresponding author) [2]; Changwei Yuan [3]; Dan Liu [1] 1. Introduction Road infrastructure forms the backbone of transport activities, which plays an important role [...]

Perovskite nanocrystals, which are well-known for their outstanding optoelectronic properties, have attracted widespread attention for several photonic and optoelectronic technologies. However, the inherent instability of perovskite nanocrystals limits their practical applications. Therefore, herein, we developed a calcium- and fluorine-ion combined-treatment method to enhance the stability of perovskite nanocrystals, which not only exhibited near unity photoluminescence efficiency and cubic morphology, but also possessed excellent photostability and thermal resistance. Additionally, the light-emitting diodes incorporating these perovskite nanocrystals showed pure green electroluminescence with a maximum external quantum efficiency of 11.85%, luminance as high as 20 940 cd m−2, and stable operation for up to 172 min. [ABSTRACT FROM AUTHOR]