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1. Role of collateral circulation in the recovery of left ventricular function after recanalization of chronic coronary total occlusion

Author: A. G. Badoyan, D. A. Khelimsky, A. A. Baranov, N. R. Obedinskaya, T. A. Bergen, V. Yu. Usov, S. N. Manukyan, and O. V. Krestyaninov
Subjects: chronic coronary total occlusion, percutaneous coronary intervention, heart failure, ejection fraction, magnetic resonance imaging, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim. To obtain extended data on the impact of collateral circulation on the recovery of left ventricular (LV) function after recanalization of chronic coronary total occlusion (CTO), especially in patients with reduced left ventricle ejection fraction (LVEF).Material and methods. This single-center, prospective, non-randomized study included 20 patients with single-vessel CTO with reduced LVEF (
Published: 2023
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2. Quantitative visualization assessment of the vascular wall in patients with surgical pathology of the aortic valve, aorta and brachiocephalic arteries

Author: T. A. Bergen, E. I. Zyablova, A. R. Tarkova, E. Kobelev, I. G. Nosulya, N. T. Pak, V. E. Sinitsyn, A. M. Chernyavsky, and V. Yu. Usov
Subjects: aorta, atherosclerosis, computed tomographic angiography, magnetic resonance imaging, ultrasound, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Diseases of the circulatory (Cardiovascular) system, RC666-701, Surgery, RD1-811, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract: Objective: Identification of the quantitative characteristics of changes in the arterial wall according to ultrasound, CT and MRI; development of the roadmap for the use of radiology diagnostic methods.Material and methods: 548 studies of 483 patients with atherosclerosis were analyzed (15 ultrasound studies, 483 – CTA and 50 – MRI). In the comparison group (n = 17) in patients without atherosclerosis, an analysis of MRI data of the aortic wall was performed. According to CTA, signs of atherosclerotic degeneration were assessed. According to the MRI data, indicators of aortic distensibility, Young’s modulus of the aortic wall (MPa), systolic distension of the aorta (ml), aortic wall enhancement index during contrast enhancement were calculated.Results: During the performance of ultrasound in all cases (n = 15), the analysis of the elastic properties of the aortic wall is difficult due to the artifact from calcification. Adverse CT signs of the occurrence of intraoperative vascular complications: the presence of an intraluminal thrombus, an uneven internal aortic contour of more than half of the circumference with an aortic wall thickness of more than 5 mm. According to MRI data in patients with atherosclerosis, aortic distensibility was reduced to 14.42 ± 2.95%, Young’s modulus for the aortic wall was 0.77 ± 0.26 MPa, the index of contrast enhancement of the aortic wall was 1.73 ± 0.5, the volume of systolic aortic distension was 11.48 ± 1.84 ml. In patients with vascular events in the perioperative period, systolic aortic dilatation was 9.2 ml.Conclusion: The signs which are expedient to consider when making a decision on surgical treatment have been identified. Significant limitations were identified in the assessment of elasticity by ultrasound. The wider use of MRI in atherosclerotic lesions looks promising.
Published: 2022
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3. Promising directions in the treatment of chronic heart failure: improving old or developing new ones?

Author: V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, N. N. Terentyeva, E. V. Grakova, K. V. Kopeva, V. Yu. Usov, N. P. Garganeeva, O. A. Pavlenko, Yu. V. Gorelova, and A. V. Teteneva
Subjects: хроническая сердечная недостаточность, лечение, нейрогормональные модуляторы, сакубитрил/валсартан, пекаваптан, финерон, верицигуат, ингибиторы натрий-глюкозного котранспортера 2-го типа, омекамтив мекарбил, генная терапия, сердечная ресинхронизирующая терапия, модуляция сердечной сократимости, трансплантация сердца, имплантация аппарата вспомогательного кровообращения, Medicine
Abstract: Unprecedented advances of recent decades in clinical pharmacology, cardiac surgery, arrhythmology, and cardiac pacing have significantly improved the prognosis in patients with chronic heart failure (CHF). However, unfortunately, heart failure continues to be associated with high mortality. The solution to this problem consists in simultaneous comprehensive use in clinical practice of all relevant capabilities of continuously improving methods of heart failure treatment proven to be effective in randomized controlled trials (especially when confirmed by the results of studies in real clinical practice), on the one hand, and in development and implementation of innovative approaches to CHF treatment, on the other hand. This is especially relevant for CHF patients with mildly reduced and preserved left ventricular ejection fraction, as poor evidence base for the possibility of improving the prognosis in such patients cannot justify inaction and leaving them without hope of a clinical improvement in their condition. The lecture consistently covers the general principles of CHF treatment and a set of measures aimed at inotropic stimulation and unloading (neurohormonal, volumetric, hemodynamic, and immune) of the heart and outlines some promising areas of disease-modifying therapy.
Published: 2022
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4. Features of brain magnetic resonance imaging (MRI) changes under the influence of renal denervation in patients with resistant hypertension

Author: V. A. Lichikaki, V. F. Mordovin, S. E. Pekarskiy, I. V. Zyubanova, M. A. Manukyan, E. I. Solonskaya, A. A. Vtorushina, S. A. Khunkhinova, A. E. Sukhareva, V. Yu. Usov, and A. Yu. Falkovskaya
Subjects: resistant hypertension, renal denervation, magnetic resonance imaging, hypertensive encephalopathy, cerebral protection, hypertension, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim. To study brain magnetic resonance imaging (MRI) changes in patients with resistant hypertension (HTN) after renal denervation (RD) and its cerebral protection effectiveness.Material and methods. The study included 111 patients, of whom 50 were men (45%) and 61 were women (55%), who underwent RD. The mean number of antihypertensive drugs taken regularly was 4,1±1,1. All patients underwent brain MRI and 24-hour ambulatory blood pressure monitoring before and after renal denervation. The data were statistically processed using Statistica 10,0 software.Results. After RD, a pronounced antihypertensive effect was observed with a significant reduction in systolic and diastolic blood pressure by 10,3/5,5 and 13,1/7,3 mm Hg at 6 and 12 months, respectively. Office blood pressure, daytime, and nighttime blood pressure levels also decreased (p0,05).Conclusion. RD contributes to a significant decrease in blood pressure levels and exerts a cerebral protective effect by reducing lateral brain ventricles, subarachnoid spaces, and absence of ischemia progression and intracranial hypertension after intervention.
Published: 2023
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5. Diuretic resistance in patients with chronic heart failure: mechanisms, prevention, and treatment

Author: V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, N. N. Terentyeva, I. K. Livshits, V. L. Ostanko, E. V. Grakova, K. V. Kopeva, V. Yu. Usov, N. P. Garganeeva, and Yu. V. Gorelova
Subjects: хроническая сердечная недостаточность, резистентность к диуретикам, терминология, механизмы, водно-солевой режим, секвенциальная блокада нефрона, глифлозины, ваптаны, инотропы, вазоконстрикторы, глюкокортикостероиды, серелаксин, несиритид, альбумин, ультрафильтрация, Medicine
Abstract: The authors analyzed the problem of diuretic resistance (DR) in patients with chronic heart failure (CHF). Most of the symptoms and signs of CHF are associated with hypervolemia and vascular congestion in the systemic and pulmonary circulation. The severity of the latter is the main factor which negatively affects the overall assessment of life satisfaction in patients with CHF. Since the patient, even at the incurable stage of CHF, primarily expects a rapid decrease in the severity of manifestations of decompensation from the prescribed therapy, achieving euvolemia is the essence of its short-term objective. Without diuretics, these immediate effects, according to which most CHF patients judge the qualifications of the doctor, are almost impossible to achieve. Unfortunately, apparently, not a single clinician was able to avoid disappointment in the effectiveness of CHF therapy associated with DR in their practice. As a rule, DR reflects the progressive course of CHF and is often associated with a poor prognosis. The review consistently covers the issues of terminology, diagnosis, pathogenesis, and prevention of DR, which aggravates CHF, and discusses measures aimed at restoring sensitivity to diuretics.
Published: 2022
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6. Advanced heart failure

Author: V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, N. N. Terentyeva, O. F. Sibireva, E. V. Grakova, V. Yu. Usov, and M. A. Osipova
Subjects: прогрессирующая сердечная недостаточность, определение, индикаторы, прогностическая стратификация, клинические маркеры, биомаркеры, визуализация, тест с физической нагрузкой, сопутствующие заболевания, стратегии ведения, механическая поддержка кровообращения, трансплантация сердца, Medicine
Abstract: The authors of the article have analyzed the problem of advanced heart failure (AHF). Despite significant and, it is not an exaggeration to say, revolutionary achievements in clinical pharmacology, cardiac surgery and implantation arrhythmology, the number of patients with chronic heart failure (CHF) in many countries is not decreasing, and in some, for example, in Russia, it is increasing. At the same time, unfortunately, often the immediate and longterm results of the so-called optimal therapy of CHF are disappointing for both the patient and the doctor. In 2007, experts from The Heart Failure Association of the European Society of Cardiology proposed the term AHF to refer to CHF in which optimal drug therapy, as well as cardiac resynchronization therapy, are not effective, which causes repeated hospitalizations and justifies the need for the advanced treatment methods such as heart transplantation and mechanical circulatory support, and/or transition to palliative care. The agreed positions of experts from the established cardiological communities in the Old and New Worlds on the definition, diagnostic criteria and treatment of AHF have been changing over time. Unfortunately, this evolution has not yet arrived at a consensus. The lecture consistently addresses the issues of terminology, diagnosis, prognostic stratification and routing of patients with AHF, as well as short- and long-term strategies for treating these patients.
Published: 2021
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7. 2020 Clinical practice guidelines for Myocarditis in adults

Author: G. P. Arutyunov, F. N. Paleev, O. M. Moiseeva, D. O. Dragunov, A. V. Sokolova, A. G. Arutyunov, I. V. Zhirov, O. V. Blagova, E. V. Privalova, S. A. Gabrusenko, A. A. Garganeeva, G. E. Gendlin, S. R. Gilyarevsky, D. V. Duplyakov, O. V. Zairatiants, D. E. Karateev, N. A. Koziolova, E. D. Kosmacheva, A. G. Kochetov, Yu. M. Lopatin, A. V. Melekhov, L. B. Mitrofanova, O. Yu. Narusov, S. N. Nasonova, A. V. Nedostup, S. Yu. Nikulina, Ya. A. Orlova, N. G. Poteshkina, A. P. Rebrov, M. A. Saidova, V. P. Sedov, V. E. Sinitsyn, M. Yu. Sitnikova, A. A. Skvortsov, V. V. Skibitsky, O. V. Stukalova, E. I. Tarlovskaya, S. N. Tereshchenko, V. Yu. Usov, I. V. Famin, A. I. Chesnikova, I. I. Shaposhnik, and N. A. Shostak
Subjects: myocarditis, inflammation, treatment of myocarditis, chronic heart failure, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Russian Society of Cardiology (RSC)With the participation: Eurasian Association of Therapists (EUAT), Society of Specialists in Heart Failure (OSSN), Russian Scientific Medical Society of Therapists (RNMOT), Russian Society of Pathologists, Russian Society of Radiologists and Radiologists (RSR)Endorsed by: Research and Practical Council of the Ministry of Health of the Russian Federation
Published: 2021
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8. COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

Author: E. Kobelev, T. A. Bergen, A. R. Tarkova, O. Ya. Vasiltseva, O. V. Kamenskaya, V. Yu. Usov, and A. M. Chernyavsky
Subjects: pulmonary embolism, chronic thromboembolic pulmonary hypertension, covid-19, exercise tests, cardiovascular disease, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Coronavirus disease 2019 (COVID-19) is a poorly understood and dangerous medical problem. COVID-19-related pulmonary vessels involvement is a complex set of interrelated pathophysiological processes associated with vascular endothelial dysfunction and accompanied by thrombosis of various localization, vasomotor disorders, severe respiratory failure, as well as pulmonary embolism (PE) resulting in chronic thromboembolic pulmonary hypertension (CTEPH). According to computed tomographic pulmonary angiography, the incidence of PE in patients with COVID-19 ranges from 23 to 30%. The aim of this work was to focus the doctors' attention on the risk of pulmonary hypertension in patients after COVID-19.Despite the ability of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) to infect various organs and systems, the main and most serious complications are pulmonary infiltration, acute respiratory distress syndrome, acute respiratory failure and PE, which in some cases becomes the triggering mechanism for CTEPH development. The literature review presents data on main pathological abnormalities developing in target organs during COVID-19 and playing an important role in increasing the CTEPH risk. The paper describes the main methods of instrumental investigations of CTEPH and an algorithm for its use in COVID-19 survivors.The revealed data demonstrated that the absence of obvious signs of pulmonary hypertension/CTEPH, the cardiopulmonary system abnormalities cannot be ruled out. Therefore, it seems appropriate to actively follow up COVID-19 survivors. A thoroughly, purposefully collected anamnesis, pulmonary function tests and stress echocardiography in an ambiguous clinical situation will play a leading role as they identify cardiopulmonary disorders and provide the doctor with basic information for further planning of patient management.
Published: 2021
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9. Prevention of post-infarction cardiac remodeling after using the non-cellular biomaterial in the experiment

Author: S. A. Afanasiev, D. S. Kondratyeva, V. Yu. Usov, A. I. Lebedeva, S. A. Muslimov, and S. V. Popov
Subjects: post-infarction cardiosclerosis, remodeling of the rat heart, noncellular allogenic biomaterial, exercise tolerance, end-diastolic volume, volume of damaged myocardium, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim. To assess the effect of non-cellular allogenic material (NAM) on post-infarction myocardial remodeling in the experiment.Material and methods. We ligated left descending coronary artery of control Han Wistar rats in order to simulate post-infarction cardiosclerosis (PICS), and NAM was intramyocardially administered to the experimental animals at the same time as the coronary occlusion. The formation of PICS occurred within 45 days after myocardial infarction modeling. Exercise tolerance was assessed in rats before and after exposure. Magnetic resonance imaging (MRI) of the rat heart was performed on 7th, 14th, and 45th days after myocardial infarction modeling. Postinfarction remodeling of rat heart was assessed using morphometric research methods.Results. An MRI study showed that on 7th day hearts of the rats of both groups had areas of damaged myocardium. However, on 14th day the area of damaged myocardium in rats with injection of NAM was 2 times less than in individuals with PICS, and on 45 day this difference increased 3,5 times. The increase in end-diastolic volume (EDV) of the left ventricle of control animals on 45 day amounted to 30%, whereas in rats of the experimental group, this figure was 8% of the initial values. Exercise tolerance in rats of both groups after the formation of PICS was lower than in the initial state. At the same time, in animals with injection of NAM, resistance to exercise was significantly higher than in rats of the control group. The results of morphometric studies of the heart showed that in the control group there were significantly more animals with morphologically visible infarction and left ventricular aneurysm than in the experimental group. In addition, animals of the control group were characterized by a statistically significantly higher value of heart mass/body weight ratio.Conclusion. Based on the results obtained, it can be considered that intramyocardial injections of non-cellular allogenic biomaterial manufactured according to the Alloplant® technology create conditions for stimulating the regenerative processes in the myocardium and also prevent post-infarction heart remodeling.
Published: 2019
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10. Diastolic heart failure: boundaries of term application

Author: V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, G. E. Chernogoryuk, N. N. Terentyeva, E. V. Grakova, K. V. Kopeva, V. Yu. Usov, N. P. Garganeeva, O. A. Pavlenko, and Yu. V. Gorelova
Subjects: Molecular Medicine
Abstract: Important changes regarding the understanding of the pathogenesis of chronic heart failure (CHF) marked the beginning of the millennium, and its first decade was called the decade of diastology. Even though numerous studies convincingly proved that deterioration of the left ventricular (LV) filling pressure often precedes impairment of its systolic function and a number of factors affect (especially at the onset) mainly the diastolic function without changing the conditions of blood ejection, modern classifications and approaches to CHF treatment are primarily based on the results of LV ejection fraction (EF) assessment.In recent years, diastolic heart failure (DHF) has been often overlooked and replaced by the ambiguous term “CHF with preserved EF”. However, sometimes authors use the term DHF extensively, since CHF based on myocardial insufficiency develops only via two mechanisms (systolic and / or diastolic dysfunction), and excluding one of the mechanisms allows to identify the underlying one. The term DHF can be used in clinical practice and cannot be replaced by the diagnosis of CHF with preserved EF. CHF with preserved EF is a broader concept which includes a full spectrum of cardiovascular diseases, complicated by the development of CHF without depression of the global LV contractility and requiring differentiated approaches to therapy. In addition, the results of repeated studies on LVEF in many patients may require reclassification of this CHF phenotype, which is established following the analysis of the baseline value of global LV contractility. We join M.R. Zile in the appeal to stop discriminating against the term “DHF” and present the boundaries of its correct application.
Published: 2023
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11. Distal renal denervation: cardioprotection in patients with resistant hypertension

Author: E. S. Sitkova, V. F. Mordovin, S. E. Pekarsky, T. M. Ripp, A. Yu. Falkovskaya, V. A. Lichikaki, I. V. Zyubanova, A. E. Baev, T. R. Ryabova, O. V. Mochula, and V. Yu. Usov
Subjects: resistant hypertension, myocardial damage, left ventricular hypertrophy, distal renal denervation, regression, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim. To study the effectiveness of using the anatomically optimized distal renal denervation (RDN) in comparison with the standard approach for reducing myocardial damage and left ventricular (LV) hypertrophy in patients with resistant hypertension (HTN).Material and methods. The randomized double-blind study of the efficacy and safety of distal RDN compared to conventional main renal artery intervention (ClinicalTrials.gov NCT02667912) for the treatment of resistant HTN included 26 patients. All patients were divided into two groups: group 1 (n=16) — distal RDN, group 2 (n=10) — conventional RDN. In addition to 24-hour blood pressure (BP) monitoring, initially and 12 months after the intervention, contrast- enhanced cardiac magnetic resonance imaging was performed to determine the left ventricular mass and non-coronary myocardial damage area. All patients signed informed consent. Twenty-four patients completed the present study.Results. After 12 months, the mean 24-hour BP significantly decreased after both distal RDN (from 167,2±28,5/93,2±19,3 to 147,0±13,7/81,5±9,3 mm Hg (p
Published: 2020
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12. SURGICAL CORRECTION OF CARDIAC METASTASES FROM CERVICAL CANCER

Author: V. M. Shipulin, S. L. Andreev, A. S. Pryakhin, V. V. Shipulin, L. N. Bondar, K. V. Zavadovsky, V. Yu. Usov, V. M. Perelmuter, and B. N. Kozlov
Subjects: cardiac metastasis, cervical cancer, surgical treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Metastases to the heart are extremely rare, and the reported incidence of cardiac metastasis at autopsy ranges from 1.5 to 21.8 %. In cancer patients, cardiac metastases are usually difficult to diagnose unless the patients do not complain of any related symptoms. Common tumors with cardiac metastasis potential are usually carcinomas of the lung, breast, and malignant lymphoma. The prognosis of a metastatic heart tumor is unfavorable. The average life expectancy for patients with this diagnosis is less than six months. In addition, surgical treatment of primary cardiac tumors or metastatic cardiac tumors is associated with high risk of perioperative lethality. Case report. We present a rare case of cervical cancer metastasis to the heart in a 33-year-old woman. Cytological examination revealed no evidence of disease recurrence 14 months after the completion of external beam radiotherapy. Echocardiography showed a mass in the outflow tract of the right ventricle and findings of severe pulmonary hypertension. omputed tomography and magnetic resonance imaging revealed a large right ventricular thrombus. The patient underwent surgery with artificial circulation. Pathohistological and immunohistochemical studies revealed metastasis of squamous cell carcinoma. The control echocardiography showed decrease in pulmonary hypertension. No evidence of right ventricular mass was detected. Conclusion. Cardiac metastasis should be included in the differential diagnosis in patients with complaints of dyspnea and chest pain, especially in cases with history of cancer. Surgical treatment of cardiac metastasis contributes to the prevention of cardiopulmonary complications and improvement of survival rates in this group of patients.
Published: 2018
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13. DIFFERENTIAL AND DIAGNOSTIC CRITERIA OF THE RECURRENCE OF GLIOMAS IN THE POST-OPERATIONAL PERIOD USING OF DYNAMIC CONTRAST-ENHANCED MRA AND PERFUSION MRI

Author: O. Yu. Borodin and V. Yu. Usov
Subjects: dynamic contrast-enhanced magnetic resonance angiography, perfusion, brain, tumor, progression, recurrence, stabilization, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract: Objective: to elaborate differential diagnostic criteria for recurrent gliomas after combination treatment, by using dynamic contrast-enhanced magnetic resonance angiography (DCE-MRA) and T2*-weighted perfusion magnetic resonance imaging (MRI).Material and methods. The retrospective study enrolled 16 men and 7 women (mean age 34.6±15.4 years) who had undergone multiparametric magnetic resonance imaging of the brain to prevent cancer recurrence after combination treatment. The study used the following protocols: 1) static contrast-enhanced MRI, including T2- and T1-weighted MRI, and post-contrastenhanced T1-weighted images at 5–8 minutes after DCE-MPA); 2) DCE-MPA at a dose of 0.2 mmol/kg; 3) in the presence of precontrast-enhanced T2*-weighted perfusion MRI at a dose of 0.1 mmol/kg. A morphological diagnosis was done in all cases. Tumor hemodynamics was evaluated by DCE-MRA using contrast ratios (CR or CBR) in each scanning phase, as well as contrastenhancement ratios (ER or CER) and a venous-arterial ratio in the first venous phase (VAR1). Relative Cerebral Blood Volumes (rCBV) were estimated on the contrast-enhanced T1-weighted perfusion maps. Statistical processing of the results was performed using ROC analysis.Results. According to T2*-weighted perfusion MRI and the results of a follow-up using the RECIST criteria, the investigators formed two comparison groups: 1) progressions (n = 7 (30.4%)) with increased rCBV (>1.75) and 2) stabilization (n = 16 (69.6%)) with reduced rCBV ( 1.59), stabilization was found with a decrease (VAR1
Published: 2018
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14. Prospects of the Magnetic Resonance Imaging Method for Assessing the Bioelastic Function of the Aortic Wall

Author: K. R. Bril’, A. A. Pronkin, T. N. Galyan, М. V. Malakhova, V. Yu. Usov, and V. V. Khovrin
Abstract: The distinct growth of cardiovascular diseases (CVD) and aortic diseases in the world requires accurate diagnostic methods for their early prediction. In modern research, more and more attention is paid to biomechanics and numerical models of accurate quantitative calculations. The assessment of aortic pathology using magnetic resonance imaging (MRI) acquires great clinical significance, since it makes it possible to simultaneously assess the anatomical topography and physical properties of the aorta. A broad study of changing biomechanical processes will complement the existing ideas about the basics of aneurysm formation and aortic dissection. MRI is a modern non-invasive method that provides the necessary data to as-sess the physical properties of the wall and directional flows in the aorta.
Published: 2023
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15. CONTRAST ENHANCED MRI IN THE ASSESSMENT OF THE RELATIONSHIPS OF ATHEROSCLEROTIC LESIONS OF CAROTID ARTERIES AND AORTIC WALL

Author: A. S. Maksimova, I. L. Bukhovets, A. M. Gusakova, E. E. Bobrikova, M. P. Plotnikov, E. A. Vusik, and V. Yu. Usov
Subjects: atherosclerosis, neovascularization, lipid profile, carotid arteries, aorta, Diseases of the blood and blood-forming organs, RC633-647.5, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim of the study. The relationships and connections of atherosclerotic damage of carotid arterial wall concomitant with atherosclerosis of thoracic aorta have been studied here, as from data of contrast-enhanced magnetic resonance imaging (MRI), and also bearing in mind the results of blood lipids biochemistry. Material and methods. The study patients group comprised seventeen persons (of which 12 males and five females, as old as 62.3 ± 6.2 years) with extensive atherosclerosis verified from data of complex radiologic and biochemical study. In everybody extensive MRI study with contrast enhancement has been carried out imaging both carotid, cerebral and aortic arch regions, and also blood spectrum of lipids was studied. Everybody used to be a in-patient of departments of cardiovascular surgery or of urgent cardiology, with multiple ischemic attacks in cerebral and coronary vascular areas (all seventeen) and also lower limb vascular arterial disorders (in twelve). Diabetes mellitus of type 2 with need of antidiabetic peroral treatment was present in eight of seventeen included. Carotid arterial stenotic atherosclerosis involved common carotid artery bifurcation and internal carotid artery (with bilateral critical stenosis in ten patients and with essentially monolateral one in seven patients) and was concomitant with stenosis over 50 % in one or more segment of syphone and/or intracranial part of internal carotid artery or of anterior or middle cerebral arteries. MRI study of aorta and carotid arteries has been carried out in everybody using MRI scanner with Toshiba Titan Vantage with field induction 1.5 T. Pearson’s parametric coefficient of correlation was employed for analysis of group relationships, with calculation of correlation coefficient r . Results. In all patients with atherosclerosis statistically significantly higher values of paramagnetic contrast enhancement of T1WI- SE scans of carotid artery’s wall as compared to the control group were observed. Age-matched control persons demonstrated the indices as low as 1.04 ± 0.02. In particular the index of enhancement of T1-WI of carotid arteries and aorta in patients with advanced atherosclerosis were as follows: over carotid arteries - 1.24 ± 0.17, over r aorta - 1.22 ± 0.17. When assessing the relationship between the indices of enhancement of T1-WI of aorta and of carotid arteries, a positive linear correlation was found ( r = 0.672, p < 0.05). There were no evidence for aortic dissection or aneurysm; the diameter of aorta in patients with atherosclerosis was as narrow as 2.5 ± 0.31 cm. The index of enhancement of T1-WI of carotid arteries atherosclerotic lesion and the total cholesterol level did correlate significantly ( r = 0.584, p < 0.05). There was also positive correlation between index of enhancement of T1-Scans of carotid plaque and blood triglycerides ( r = 0.667; p
Published: 2017
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16. CARDIAC MAGNETIC RESONANCE IMAGING IN DIFFERENTIAL DIAGNOSTICS OF ACUTE CORONARY SYNDROME IN PATIENTS WITH NON-OBSTRUCTION CORONARY ATHEROSCLEROSIS

Author: V. V. Ryabov, S. B. Gomboeva, Т. A. Shelkovnikova, A. Е. Baev, М. S. Rebenkova, Yu. V. Rogovskaya, and V. Yu. Usov
Subjects: acute coronary syndrome, non-obstructive coronary atherosclerosis, magnetic resonance tomography, myocardial infarction, myocarditis, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim. To investigate on the nosological structure of acute coronary syndrome (ACS) in patients with non-obstruction coronary atherosclerosis (NOCA) before and after magnetic resonance imaging (MRI) of the heart.Material and methods. A non-randomized, open, controlled study (NCT02655718). The patients included, with ACS, older than 18 y.o., with NOCA (intact coronary arteries or stenosis ≤50%) confirmed by invasive coronary arteriography (ICAG). Patients with previous revascularization were not included.Results. In the year 2016, to emergency cardiology department (ECD) 913 ACS patients admitted. In 44 (4,8%) the NOCA was found. Mean age 54±10,4 y.o., males 68%, and the groups with ACS with ST elevation (STEACS) and none (NSTEANS) were comparable by clinical and anamnestic parameters. Intact coronary arteries were visualized in 16 (53%), non-significant coronary atherosclerosis was diagnosed in 14 (32%), slower coronary flow — 22 (73%). By MRI with contrast, performed in 11±8 days (2-43 days) from ACS beginning, myocardial oedema was found in 18 (41%), hyperemia in 13 (30%) and fibrosis in 40 (91%); there were no changes in 1 patient.Nosological structure of ACS in NOCA after MRI has been represented: by acute myocardial infarction (MI) in 24 (55%) cases, unstable angina (UA) — in 6 (14%), pseudocoronary myocarditis in 10 (23%), acute aorta dissection in 1 (2%), posttraumatic atherosclerosis in 1 (2%), congenital valve defect in 1 (2%), manifested Wolf-Parkinson-White (WPW) — in 1 (2%). In-hospital mortality was 2%. In comparison of ACS before and post MRI there was significant increase number of patients with myocarditis, by 20%.Conclusion. The prevalence of ACS in NOCA is 4,8%, that is comparable to literature data. Patients with ACS and NOCA are heterogenic group with MI, UA, myocarditis, acute aorta dissection, posttraumatic atherosclerosis, congenital defects, WPW syndrome. In-hospital mortality was 2%. Comparing the structure of the diagnoses before and after MRI, there was significant increase of myocarditis patients number. A high accuracy of MRI was found for differential diagnostics of ACS in NOCA, which was 78%.
Published: 2017
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17. Contrast enhanced magnetic resonance imaging in early assessment of atherosclerotic lesion of abdominal aortic wall and common iliac arteries

Author: A. S. Maksimova, V. E. Sinitsyn, and V. Yu. Usov
Subjects: Rehabilitation, Emergency Medicine, Surgery, Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine
Abstract: Highlights. Early atherosclerotic changes in the abdominal aortic wall and common iliac arteries in patients without clinical manifestations of critical atherosclerotic stenosis of the lower extremity arteries were studied using contrast enhanced magnetic resonance imaging. A method for quantitative characterization of the accumulation of paramagnetic contrast in the abdominal aortic wall and common iliac arteries is presented.Aim. To study the pattern of early atherosclerotic lesions of the abdominal aortic wall and common iliac arteries in patients without clinical manifestations of critical atherosclerotic stenosis of the lower extremity arteries using paramagnetic contrast enhancement (CE-) MRI.Methods. The retrospective study included 36 patients (25 men, 11 women) who underwent MRI of the lumbar spine with CE, without signs of atherosclerosis of the lower extremities. Subsequently, 2.5 and 4 years after CE-MRI, two patients developed acute leg ischemia and required vascular surgeries. At the time of the study, both had higher levels of C-reactive protein in the blood (6.3 mg/L and 5.9 mg/L, while the other patients had Results. Depending on the IE of the abdominal aortic wall in CE-MRI, patients were divided into three groups: group 1 (n = 11) with IE ≤1.05; group 2 (n = 16) with 1.05 1.15. The aortic IE in all three groups was 1,03 (1,01;1,03); 1,10 (1,09;1,15); 1,36 (1,16;1,40) respectively (pConclusion. The state of the abdominal aortic wall and common iliac arteries should be evaluated, and IE of T1-w should be calculated when performing CE-MRI examination of the area of the descending aorta to assess pathological neoangiogenesis as the most important component of atherogenesis.
Published: 2022
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18. Relationship of mri pattern of carotid atherosclerotic plaque to cerebrovascular reactivity in carotid stenosis

Author: A. S. Maksimova, E. E. Bobrikova, M. P. Plotnikov, Yu. V. Rogovskaya, I. L. Bukhovets, M. S. Kuznetsov, and W. Yu. Usov
Subjects: carotid atherosclerosis, сarotid arteries, mri, stroke risk, сerebrovascular reactivity, Diseases of the blood and blood-forming organs, RC633-647.5, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: The aim of the study was to compare the structure of atherosclerotic plaques visualized using MRI with cerebral vascular reactivity detected by ultrasound in patients with carotid atherosclerosis. Materials and methods. The patients′ population comprised 21 persons (mean age 64 ± 13) with hemodynamically significant carotid artery stenosis for over 70 % of lumen. All patients underwent MR imaging of the carotid arteries. To assess the cerebrovascular reactivity transcranial ultrasound of middle cerebral artery was done and blood flow parameters were determined during the stress tests: test with breath holding and hyperventilation. Results and discussion. It was found that at test with breath holding there is a statistically significant association between MRI plaque structure and direction of the reaction (p = 0.081), whereas at the test with hyperventilation no significant differences were found. At tests with breath holding in 56 % patients with MR images of plaque hypointense on T1-weighted scans and hyperintense on T2-weighted ones unidirectional positive response was observed; unidirectional negative response or multidirectional response were observed in patients with MR images of plaque hyperintense on T1-weighted scans and hypointense on T2-weighted ones. Conclusion. Atherosclerotic lesions of the internal carotid artery with intra-plaque hemorrhage are accompanied by critical deterioration of cerebrovascular reactivity. Thus, every hemorrhage to carotid plaque is critical risk factor and requires removal of the plaque by carotid endarterectomy. Such study may be suggested as a screening test in all patients of risk groups of atherosclerosis.
Published: 2015

19. CONTRAST MAGNETIC RESONANCE INVESTIGATION IN PATIENTS AFTER MYOCARDIAL INFARCTION AND TACHIARRHYTHMIAS

Author: V. Yu. Usov, V. E. Babokin, O. V. Mochula, M. S. Khlynin, P. I. Lukyanenok, T. A. Shelkovnikova, E. E. Borodina, I. O. Kurlov, A. I. Petsh, and R. E. Batalov
Subjects: mri of the heart with contrast, atrial tachiarrhythmias, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: We present the results of MRI study of the heart with paramagnetic contrasting for visualization of the foci of myocardial damage, that lead to atrial tachiarrhythmias in patients with severe infarction of the left ventricle. It is shown that the volume of the left atrium more than 75 cm3 and accumulation of paramagnetic contrast in atrial myocardium with the enhancement T1-adj. spin-echo regimen index more than 1,27 are prognostic factors for atrial tachiarrhythmias, and MRI of the heart with contrast is an important additional method of patients’ investigation with atrial rhythm disorders.
Published: 2014
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20. Contrast-enhanced mri imaging of atherosclerotic lesions of the aortic wall

Author: A. S. Maksimova, V. E. Babokin, I. L. Bukhovets, E. E. Bobrikova, Yu. V. Rogovskaya, P. I. Lukyanenok, and V. Yu. Usov
Subjects: atherosclerosis of aorta, mri, contrast-enhanced imaging of plaques, chest mri, Diseases of the blood and blood-forming organs, RC633-647.5, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Aim of the study. To analyze MR tomographic imaging features of atherosclerotic lesions of the aorta, with a paramagnetic contrast enhancement, in patients with extensive atherosclerosis and old acute myocardial infarction (AMI). Material and methods. The patients population comprised 33 patients with multiple atherosclerosis and old transmural AMI of the left ventricle. As control group eight patients with tumor pathology of the thorax were employed, without evidence of clinically significant atherosclerosis of the same age range. All patients underwent contrast-enhanced study (paramagnetic in standard dose of 0.1 mmol / kg BW) and index of enhancement (IE) of T1-weighted images was calculated as the ratio of intensities over the aortic wall on contrast and initial MRI studies. Geometric diameter and wall thickness of the aorta at the level of accumulation of contrast-paramagnetic material were also determined. Results and discussion. In 25 (76 %) patients with extensive atherosclerosis and old AMI IE of the atherosclerotic lesions in the aortic wall in all cases was over 1.14 (mean 1.17 ± 0.13), far more than increasing of intensity in the control group. In eight patients (24 %) the lack of accumulation of contrast-paramagnetic material in the aortic wall was noted. Types of accumulation of contrast paramagnetic was assigned as a local or diffuse accumulation syndrome, depending on the length and circularity of the lesions. A local syndrome of accumulation was found in 15 patients, with IE = = 1.09 ± 0.06, aortic diameter and wall thickness at the level of accumulation of contrast equal to 2.66 ± 0.35 cm and 0.5 ± 0.13 cm, respectively. Diffuse type of accumulation was found in 10 patients in this case IE = 1.26 ± 0.13 aortic diameter and the wall thickness at the accumulation of contrast are 2.4 ± 0.34 cm and 0.53 ± 0.11 cm, respectively. In the control group no significant accumulation of contrast paramagnetic material in the aortic wall was observed, IE did not exceed 1.04 (mean 1.01 ± 0.02). Conclusion. Contrast-enhanced MRI allows to visually and quantitatively assess pathology of aortic wall in atherosclerosis.
Published: 2014

21. CASE OF PSEUDOCORONARY PRESENTATION OF MYOCARDITIS WITH ST SEGMENT ELEVATION

Author: S. B. Gomboeva, V. V. Ryabov, T. A. Shelkovnikova, V. Yu. Usov, V. A. Markov, and R. S. Karpov
Subjects: acute coronary syndrome, non-obstructive atherosclerosis, myocarditis, cardiac mri, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Clinical case demonstrates the necessity for multimodal visualization of the heart in differential diagnostics of acute coronary syndrome with ST elevation in patients with non-obstruction coronary heart disease. This made possible to be sure on the diagnosis of pseudocoronary variant of myocarditis, to prescribe etiotropic and pathogenetic treatment. On-time diagnostics of alternative causes of chest pain may help to avoid unnecessary treatments related to acute myocardial infarction.
Published: 2016
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22. ВВЕДЕНИЕ В РОССИИ ИНСТИТУТА ДЕКЛАРИРОВАНИЯ ИМУЩЕСТВА ДОЛЖНИКОМ: ЗА И ПРОТИВ

Author: K. Yu. Usov
Published: 2019
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23. Structure of Rat Testicles after Intravenous Injection of Nanosized Magnetite Particles

Author: I. V. Sukhodolo, V. Yu. Usov, I. V. Mil’to, and V. V. Ivanova
Subjects: Male, 0301 basic medicine, Radiochemistry, Connective tissue, General Medicine, General Biochemistry, Genetics and Molecular Biology, Rats, 03 medical and health sciences, Magnetite Nanoparticles, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, chemistry, Injections, Intravenous, Testis, Magnetic nanospheres, medicine, Animals, Nanospheres, 030217 neurology & neurosurgery, Magnetite
Abstract: The structure of the testicles was studied in adult rats in 120 days after a single intravenous injection of chitosan-modified (magnetic nanospheres) and lipid-modified (magnetoliposomes) nanosized magnetite particles. Perls histochemical reaction detected in the testicular interstitial connective tissue the cells which absorbed and accumulated magnetite nanoparticles. The dynamics of spermatogenesis index and the count of Perls+ cells in the rat testicles were traced throughout the experiment. The studied modified nanosized magnetite particles did not penetrate through the blood-testicle barrier in rats.
Published: 2019
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24. [An effect of mexidol on the level of corsticosteron in the blood serum and beam zone cells in rats with light desynhronizes and physical loads]

Author: O A Del, V V Yartsev, N V Naryzhnaya, M V Svetlik, O. B. Zhukova, T A Zamoshchina, K V Zaitsev, A. A. Gostyukhina, A. V. Prokopova, and V. Yu. Usov
Subjects: Male, Serum, medicine.medical_specialty, Sodium, Physical activity, chemistry.chemical_element, 030209 endocrinology & metabolism, 050109 social psychology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Blood serum, Corticosterone, Internal medicine, Germany, Medicine, Animals, 0501 psychology and cognitive sciences, Statistical processing, business.industry, Adrenal cortex, 05 social sciences, Standard methods, Rats, Psychiatry and Mental health, Endocrinology, medicine.anatomical_structure, chemistry, Picolines, Neurology (clinical), business, Bright light
Abstract: In order to develop methods and means of maintaining normal human functioning under conditions of desynchronizes, the effect of mexidol on the level of corticosterone in the blood serum and the state of the cells of the beam zone of the adrenal cortex of rats after light or dark deprivation and physical activity to a state of fatigue.The experiments were performed on 7 groups of rats (10 animals each) in the spring. The model of physical activity is the method of forced swimming of rats until exhaustion in its own modification. For the induction of experimental desynchronizes, the animals of the experimental groups were kept around the clock for 10 days with artificial bright light of 150 LX or a complete darkening of 2-3 LX. Mexidol was administered intramuscularly at a dose of 10 mg/kg animal 30 minutes before the swimming test. Control animals under similar conditions were administered 0.9% sodium chloride solution. The level of corticosterone in the serum was determined using enzyme immunoassay. The measurements were carried out on a programmable photometer for STAR FAX 303 PLUS microsamples (USA). Histological analysis of the adrenal glands was carried out according to standard methods. Microscopy of preparations, imaging and measurements were carried out using an Axio Lab A1 microscope, an AxioCamERc 5s camera and ZEN 2012 software («Carl Zeiss Microscopy», Germany). Statistical processing of the results was carried out using standard parametric and non-parametric methods, depending on the nature of the distributions.Mexidol under combined successive stress loads - desynchronizes and physical activity - demonstrated anti-stress properties not only at the level of corticosterone in the blood serum of rats, but also at the level of adrenal glands. The severity of this effect of the drug depended on the number of stress loads (isolated physical or shown in conditions of desynchronizes), the phase of stress and the nature of deprivation. Under natural lighting conditions and after light deprivation, when animals were in the anxiety phase of varying severity, the drug worked more reliably than after dark deprivation in conditions of developing depletion. Nevertheless, even in the latter case, he showed himself as a means of preventing exhaustion in animals and the breakdown of adaptation.Изучение влияния мексидола на уровень кортикостерона в сыворотке крови и состояние клеток пучковой зоны коры надпочечников крыс после световой или темновой депривации и физической нагрузки до состояния утомления.Эксперименты выполнены на 7 группах крыс (по 10 особей) весной. Моделью физической нагрузки выбрана методика в собственной модификации принудительного плавания крыс до полного утомления. Для индукции экспериментального десинхроноза животные опытных групп в течение 10 сут круглосуточно находились при искусственном ярком освещении 150 LX либо полном затемнении 2—3 LX. Мексидол вводили внутримышечно в дозе 10 мг/кг животного за 30 мин до плавательного теста. Контрольным животным в аналогичных условиях вводили 0,9% раствор натрия хлорида. Уровень кортикостерона в сыворотке крови определяли с помощью иммуноферментного анализа. Измерения проводили на программируемом фотометре для микрострипов STAR FAX 303 PLUS (США). Гистологический анализ надпочечников проводили по стандартным методикам. Микроскопию препаратов, изготовление снимков и измерения осуществляли с использованием системы из микроскопа AxioLab A1, камеры AxioCamERc 5s и программного обеспечения ZEN 2012 («Carl Zeiss Microscopy», Германия). Статистически результаты обрабатывали стандартными параметрическими и непараметрическими методами в зависимости от характера распределений.Мексидол в условиях сочетанных, последовательно предъявляемых стрессорных нагрузок — десинхроноза и физической нагрузки — продемонстрировал противострессорные свойства на уровне не только содержания гормона кортикостерона в сыворотке крови крыс, но и адренокортикоцитов пучковой зоны надпочечников. Выраженность этого воздействия препарата зависела от количества стрессорных нагрузок (изолированная физическая или предъявляемая в условиях десинхроноза), фазы стресса и характера депривации. При естественных условиях освещения и после световой депривации, когда животные находились в фазе тревоги разной степени выраженности, препарат срабатывал надежнее, чем после темновой депривации в условиях развивающегося истощения. Тем не менее даже в последнем случае он показал себя как средство, предупреждающее истощение и срыв адаптации у животных.
Published: 2020

25. USE OF MIDDLE-FIELD MRIWITH SPECIFIC SEQUENCIES COMPENSATING THE MOVEMENT ARTEFACTS FOR BRAIN STUDIES IN PATIENTS WITH HIV INFECTION

Author: T. A. Shelkovnikova, E. V. Fedorenko, E. M. Kazakova, P. E. Lutsenko, V. A. Arkhangelsky, and W. Yu. Usov
Subjects: medicine.medical_specialty, Physical medicine and rehabilitation, business.industry, Movement (music), Field (Bourdieu), medicine, Human immunodeficiency virus (HIV), In patient, medicine.disease_cause, business
Abstract: Nowadays of great importance is not only the issue of early diagnosis of HIV infection, but of early detection and effective treatment of AIDS complications. The annual increase in the incidence of HIV infection amounts to 4%. Unfortunately, a great number of patients ask for hospital care when their disease has the stage of secondary complications. Such situation requires a fast and affordable diagnostics together with verification of the nature of the affection. Purpose. To evaluate the diagnosis effectiveness of the secondary infectious cerebral affection in patients with HIV infection using the method of non-contrast MRI including the usage of the specially developed software. One hundred thirty three patients were recruited for the study, the main group of 108 persons (as old as 36,8±8,3), all referred to the brain MRI with suggestion of neurologic complications of HIV. The control group comprised 25 patients of the same age with focal damage of vascular nature. In everybody the MRI has been carried out using open middle-field scanner (Az-360, by AZ plc company, Moscow) with field induction 0,4 T, supplied with wireless four-channel quadratur coil for head studies, without contrast enhancement, but using in everybody the specially designed protocols for compensation of movement artifacts. All patients were re-examined in 2, 4 and 6 weeks. MRI images both in first admission and in follow-up studies were reported first qualitatively by type of contour of pathologic focus, by presence of multiple pattern of focal damage, by ultrastructure of foci, extent of perifocal oedema, interhaemispheric dislocation; also the dimensions of lateral ventriculi, of external subarachnoidal spaces and thickness of cortex in various regions were measured. Focal cerebral damage verified later as toxoplasmosis was revealed in the main group in 80% (86 of 108) of patients. False-negative and false-positive conclusions of MRI studies were not revealed also in prospective follow-up studies. Of these in 69 (80,2%) the pathologic foci were multiple and did localize periventricularly in particular in putamen, nucleus caudatus, equally frequent for both haemispherae, single foci were detected in thalami, concomitant with tendency to extensive cortical dystrophy. The putamen region was involved more frequently as compared to other basal ganglii (р=0,003). No significant differences were revealed between various cortical regions as regard to frequency of detection of pathologic foci. Four weeks period was detected as being the most effective time for the dynamic control in the course of treatment. Conclusion. Middle-field MRI of the brain with compensation of movement artifacts is a proper technique for both the diagnosis and follow-up control of treatment of cerebral toxoplasmosis in patients with HIV infection.
Published: 2018
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26. CONTRAST-EHANCED MRI IN TIME-STRUCTURE ANALYSIS OF MYOCARDIAL DAMAGE IN ACUTE INFARCTION AND EARLY PREHOSPITAL THROMBOLYTIC THERAPY

Author: S. P. Yaroshevsky, O. I. Belichenko, V. Yu. Usov, O. V. Mochula, A. E. Baev, Vyacheslav Ryabov, E. V. Vyshlov, Ya. V. Alekseeva, S. A. Karedva, and T. A. Bakhmetyeva
Subjects: medicine.medical_specialty, Percutaneous, Radiological and Ultrasound Technology, business.industry, medicine.medical_treatment, Blood flow, Thrombolysis, 030204 cardiovascular system & hematology, Chest pain, medicine.disease, 030218 nuclear medicine & medical imaging, Gadobutrol, Contractility, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Angioplasty, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Myocardial infarction, medicine.symptom, business, medicine.drug
Abstract: Purpose:to evaluate the dependence of absolute and relative thickness of damaged myocardium in the acute myocardial infarction (AMI) area from the time interval between oncet of pain and start of intravenous thrombolysis (so-called “pain–needle time”), in AMI patients treated with prehospital intravenous thrombolysis and also later on with subsequent percutaneous coronary angiplasty (PCA) and stenting, using contrast-enhanced MRI of the heart Materials and methods. The study comprised data of CE-MRI studies in 25 patients with theyr first acute myocardial infarction, in whom the pre-hospital thrombolytic therapy (TLT) was carried out in the course of 35–300 min after onset of chest pain, with coronarography and percutaneous coronary angioplasty and stenting after admission to the institute of cardiology. In six patients the TLT was not success ful and in these the restoration of coronary blood flow was obtained only at PCA. In all patients in terms 18–34 hours after TLT the CE-MRI of the heart was carried out using gadobutrol or gadoversetamid, as 0.1 mM per kg of BW, in T1-weighted mode with fat suppression and as inversion-recovery with inversion time adjusted to get the normal myocardium “nulled”. We calculated the segmental extension of damage, the thickness of infarcted irreversibly damaged myocardium and of non-damaged myocardium in the same locations, the index of transmurality, as ratio of thickness of damaged myocardium to the overall wall thickness. We analyzed the dependence of these indices of damage from the time interval between pain oncet and beginning of intravenous thrombolytic therapy (or PCA – when TLT was unsuccessful).Results.The dependence of thickness of non-damaged myocardium from the “pain-needle” time was as exponential as Y = 2.08 + 17.11 · exp(−t/42.4), r = 0.843, p < 0.002. Index of transmurality did depend on the time interval “pain – needle” as Boltzmann function, pretty closely to reverse exponential one: No-reflow zone with absent blood flow in the infarcted area was present only in cases with the “pain–needle” time interval over 70 min. Later on the full or partial restoration of contractility in infarcted segments was observed only if the IT was below 0.55–0.6.Conclusion.CE-MRI delivers adequate quantitative estimates of anatomic transmural extent of myocardial infarction from early acute period of the AMI. The depth of myocardial damage is a function of “pain–needle” time and approaches the half of wall thickness for as short as 55–65 min, determining by this the future prognosis of the mechanical restitution of contractility in the infarcted region. It is suggested the CE-MRI of the heart must be carried out in every patient in whom due to AMI the thrombolytic therapy and/or percutaneous coronary angioplasty has been done, for unbiased myocardium-focused control of efficiency of restoration of coronary arterial patency.
Published: 2018
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27. Relaxivity of Paramagnetic Complexes of Manganese and Gadolinium

Author: M. Yu. Sannikov, Victor D. Filimonov, V. M. Gukasov, N. L. Shimanovskii, O. Yu. Borodin, Yu. L. Rybakov, V. Yu. Usov, and M. L. Belyanin
Subjects: Pharmacology, Aqueous solution, 010405 organic chemistry, Gadolinium, Inorganic chemistry, Pharmacology toxicology, chemistry.chemical_element, Manganese, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Paramagnetism, chemistry, Drug Discovery
Abstract: The relaxivities of aqueous solutions of the manganese complexes Mn-CDTA, Mn-DTPA, and Mn-EDTA were compared with that of the gadolinium complex Gd-DTPA. Relaxivities R1 and R2 of Mn-CDTA solutions were slightly greater than those of Gd-DTPA. The lowest relaxivities were seen for Mn-DTPA, while Mn-EDTA occupied an intermediate position between Mc-CTDA and Mn-DTPA.
Published: 2019
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28. ULTRASOUND CONTRAST IMAGING IN DIAGNOSIS OF LEFT VENTRICLE ANEURYSM WITH THROMBOSIS

Author: A. S. Maksimova, Boris N Kozlov, V. Yu. Usov, I.L. Bukhovets, and S. L. Mikheev
Subjects: medicine.medical_specialty, Ejection fraction, business.industry, Ultrasound, medicine.disease, Coronary artery disease, Left Ventricular Aneurysm, Aneurysm, medicine.anatomical_structure, Ventricle, Internal medicine, cardiovascular system, medicine, Cardiology, cardiovascular diseases, Thrombus, business, Contrast-enhanced ultrasound
Abstract: Aim: to study the possibility of use of contrast-enhanced echocardiography with SonoVue™ in evaluation of the left ventricle structural features. Here we present clinical case demonstrating the use of second generation ultrasound contrast agent for assessment of the structural features of the left ventricle in patients with coronary artery disease and post-infarction left ventricular aneurysm. In the course of routine ultrasound heart study, there was no clear definition of apical endocardial borders, of left ventricular volume, aneurysm, and the presence and size of the thrombus. Ultrasound contrast agent provided clear visualization of the endocardial borders, allowing for more accurate measurements of volumes, ejection fraction, and size and volume of thrombus. Echocardiography with contrast agents significantly improves the quality of ultrasound images and enhances the diagnostic role of noninvasive diagnostics.
Published: 2018
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29. Rhythmoinotropic Response of Papillary Muscles in Rats with Different Severity of Postinfarction Cardiosclerosis

Author: D. S. Kondratieva, Sergey V. Popov, S. A. Afanasiev, and V. Yu. Usov
Subjects: Male, Inotrope, medicine.medical_specialty, Myocardial Infarction, Stimulation, 030204 cardiovascular system & hematology, Hippocampus, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Receptors, Glycine, 0302 clinical medicine, Adrenocorticotropic Hormone, Cerebellum, Internal medicine, Occlusion, medicine, Animals, Hippocampus (mythology), Myocardial infarction, business.industry, Myocardium, General Medicine, Papillary Muscles, Receptors, GABA-A, medicine.disease, Coronary Vessels, Peptide Fragments, Rats, Neuroprotective Agents, medicine.anatomical_structure, Endocrinology, Coronary occlusion, Cardiology, business, 030217 neurology & neurosurgery, Left ventricular wall, Artery
Abstract: We studied the dependence of post-rest positive inotropic response of isolated rat papillary muscles subjected to rhythmic stimulation on severity of postinfarction cardiosclerosis developed during 6 weeks after occlusion of the left descending coronary artery. The isolated papillary muscles were perfused with oxygenated Krebs-Henseleit solution and electrically stimulated at a rate of 0.5 Hz. In all rats, coronary occlusion provoked postinfarction cardiosclerosis with the formation of a scar occupying 20-50% (min-max of the sample) of the left ventricular wall. Despite the presence of large postinfarction scar in all rats, the positive post-rest inotropic responses greatly varied. The post-rest response in rats with scar occupying37% left ventricular wall was similar to that in intact animals, but rats with scar area44% demonstrated dramatically decreased inotropic response to rest periods.
Published: 2017
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30. QUANTITATIVE PLANNING OF NEUTRON CAPTURE THERAPY ACCORDING TO THE KINETICS DATA OF Gd (III) COMPLEXES WITH MAGNETIC RESONANCE IMAGING

Author: V. Yu. Usov, A. R. Wagner, M. I. Bakhmetyeva, N. V. Savello, M. L. Belyanin, and N. I. Karpovich
Subjects: Neutron capture, Materials science, Nuclear magnetic resonance, medicine.diagnostic_test, Kinetics, medicine, Magnetic resonance imaging
Published: 2017
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31. THE USAGE OF OUT PATIENT CONTRAST-ENHANCED ECHOCARDIOGRAPHY FOR DEFINITION AND SEVERITY ASSESSMENT OF POSTINFARCTION LEFT VENTRICULAR ANEURISM

Author: S. L. Mikheev, A. S. Maksimova, Boris N Kozlov, I.L. Bukhovets, and V. Yu. Usov
Subjects: medicine.medical_specialty, Severity assessment, business.industry, Internal medicine, media_common.quotation_subject, Cardiology, Medicine, Contrast (vision), Radiology, Nuclear Medicine and imaging, business, media_common
Published: 2017
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32. EVALUATION OF THE INFLUENCE OF RENAL CYSTS ON THE LEVEL OF ARTERIAL PRESSURE REDUCTION AFTER RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION. THE BIENNIAL INSPECTION

Author: N. I. Ryumshina, E. A. Vusik, P. I. Luk’yanenok, Viktor Mordovin, S. E. Pekarskyj, and V. Yu. Usov
Subjects: Denervation, Intravenous contrast, education.field_of_study, medicine.medical_specialty, business.industry, Radiofrequency ablation, Renal parenchyma, Population, Surgery, law.invention, Blood pressure, Renal cysts, law, Medicine, In patient, business, education, Nuclear medicine
Abstract: Aim. We evaluated the influence of renal cysts on the efficiency of reduction of arterial pressure in patients with treatment-resistant hypertension after renal denervation. Materials and Methods. A total of 33 patients (aged 57.8±8.75 years) with treatment-resistant hypertension were included. All patients underwent radiofrequency ablation (RFA) of the sympathetic nerves of renal arteries. The average level of arterial pressure was as high as 137–210/57–148 mm Hg according to 24-h monitoring. MRI studies were performed using MRI scanner “Titan Vantage” (by Toshiba Medical Ltd., 1.5 Т) in T1-W and T2-W spin-echo models. After this, the intravenous contrast enhancement was carried out (with 0.5 М solution, 0.2 ml/Kg), with subsequently repeated acquisition of Т1-weighted spin-echo images 3-5 min after contrast injection, employing exactly the same protocols as before enhancement. Results. Preoperative images demonstrated cysts in kidneys in half of patients (16 individuals). Positive effect (the arterial pressure decreased by 10 mm Hg) was observed in 70% of them. However, in 30% of population, the arterial pressure increased. Among the patients without cysts in the kidneys, negative effect was observed in 8% only, and positive effect was found in 77% of patients (arterial pressure decreased by over 20 mm Hg). Conclusion. There is a statistically significant trend towards a greater antihypertensive effect of renal denervation in patients without cystic changes in the renal parenchyma (cortex). Thus, MRI is of prognostic value for prediction of renal denervation efficacy.
Published: 2017
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33. Influence of Sialadenectomy on the Development of Spermatogenesis in Rats: Ultrastructural Characteristics of Spermatogenic Epithelium and Leydig Cells

Author: I. V. Mil’to, V. Yu. Usov, I. V. Sukhodolo, and V. V. Ivanova
Subjects: 0301 basic medicine, Spermatogenic epithelium, Male, Sertoli Cells, Time Factors, Leydig Cells, General Medicine, Biology, Adaptation, Physiological, General Biochemistry, Genetics and Molecular Biology, Salivary Glands, Cell biology, Rats, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Seminiferous Epithelium, Ultrastructure, Animals, Outbred Strains, Endocrine system, Animals, Spermatogenesis, 030217 neurology & neurosurgery
Abstract: Sialadenectomy in young rats modifies the development of the spermatogenic and steroidogenic functions of the testes. Sialadenectomy causes ultrastructural changes in spermatogenic cells, sustentocytes, and Leydig cells that disappear by week 8 of the experiment due to realization of compensatory and adaptive mechanisms. The effects of endocrine factors of the greater salivary glands on the spermatogenic cells are realized directly and indirectly via interstitial endocrinocytes and sustentocytes.
Published: 2018

34. [Simultaneous magnetic resonance angiographic and tomographic assessment of atherosclerotic plaques of carotid arteries with paramagnetic contrasting by cyclomang]

Author: V Yu, Usov, M L, Belyanin, E E, Bobrikova, O Yu, Borodin, N L, Shimanovsky, T V, Minenko, I L, Bukhovets, M P, Plotnikov, B N, Kozlov, and V M, Shipulin
Subjects: Male, Carotid Arteries, Contrast Media, Humans, Reproducibility of Results, Carotid Stenosis, Female, Middle Aged, Tomography, X-Ray Computed, Edetic Acid, Magnetic Resonance Angiography, Plaque, Atherosclerotic, Aged
Abstract: The authors studied a possibility of simultaneously performing magnetic resonance (MR) angiography of carotid arteries and contrast-enhanced MR tomography of atherosclerotic plaques of carotid arteries. We examined a total of 16 patients presenting with disseminated atherosclerosis and 8 patients of the control group. Quadrature coils for examination of the head were used in order to sequentially perform MR tomography of the brain, MR angiography of carotid arteries and MR tomography of atherosclerotic plaques of carotid arteries with contrasting by 0.5M cyclomang. Angiography was carried out by means of the technique of 3D GR FFE of rapid gradient echo (TR/TE/FA/ST=10 ms/2.7 ms/20°/1.5 mm). MR tomography of the carotid arteries bifurcation was performed in the T1-weighted spin-echo mode: TR=500-900 ms, TE=10 ms, slice sickness 1-3 mm into the matrix 256x256 voxels, with the voxel size measuring 0.2x0.2x2 mm. The average time of passing of the paramagnetic through the blood vessels of the cerebral hemispheres in the control group amounted to 4.23±0.14 s for the left hemisphere and to 4.27±0.15 s for the right one. The mean time of bolus passing in patients with predominantly unilateral stenosis of the internal carotid artery amounted to 4.89±0.23 on the affected side, equalling 4.56±0.19 s on the unaffected side (p0.05). In bilateral lesions these indices for the left and right hemispheres amounted to 4.98±0.21 s and 5.01±0.16 s (p0.05), respectively. Contrast-enhanced MR angiography with cyclomang made it possible in all cases to visualize the localization and character of stenosis. The index of stenosis degree calculated for MR-angiogram highly significantly correlated with the indices of the ultrasonographic examination performed according to the ECST technique both for cases of unilateral (r=0.87, p0.05) and cases of bilateral stenotic lesion (r=0.85, p0.05). Inhomogeneous soft plaques with high content of lipids had high values of the enhancement index on contrasting--1.26±0.07, whereas hard fibrous avascular plaques--1.09±0.04 (p0.05). The total time of the examination amounted to 41±5 min while performing time-fly MR-angiography and to 29±5 min without it. A conclusion was made that simultaneous MR angiography and contrast-enhanced (with Mn-paramagnetic) MR tomography of carotid arteries is possible and appropriate within the framework of a single study using quadratic coil for the head.Исследована возможность одновременного проведения магнитно-резонансной (МР) ангиографии сонных артерий и контрастной МР-томографии атеросклеротических бляшек сонных артерий. Обследовано 16 больных с распространенным атеросклерозом и 8 пациентов контрольной группы. С помощью квадратурных катушек для исследования головы были последовательно проведены МР-томография головного мозга, МР-ангиография сонных артерий и МР-томография атеросклеротических бляшек сонных артерий с контрастированием 0,5 М цикломангом. Ангиография выполнялась с использованием техники 3D GR FFE быстрого градиентного эхо (TR/TE/FA/ST=10мс/2,7мс/20°/1.5 мм). МР-томография бифуркации сонных артерий проводилась в Т1-взвешенном спин-эхо режиме: TR=500–900 мс, TE=10 мс, толщина среза 1–3 мм, в матрицу 256х256 вокселей, размер вокселя 0,2х0,2х2 мм. Среднее время прохождения парамагнетика по кровеносному руслу больших полушарий составляло в контрольной группе 4,23±0,14 с. для левого и 4,27±0,15 с. для правого полушария. Среднее время прохождения болюса у пациентов с преимущественно односторонним стенозом внутренней сонной артерии составило 4,89±0,23 с. на пораженной стороне, тогда как на непораженной – 4,56±0,19 с. (p0,05). При двустороннем поражении эти показатели для левого и правого полушарий составляли 4,98±0,21 с. и 5,01±0,16 с. (p0,05). Контрастная МР-ангиография с цикломангом позволила во всех случаях визуализировать локализацию и характер стеноза. Показатель степени стеноза, рассчитанный для МР-ангиограммы, высоко достоверно коррелировал с показателями ультразвукового исследования, выполненного по методике ECST, как для случаев одностороннего (r=0,87, p0,05), так и для случаев двустороннего стенотического поражения (r=0,85, p0,05). Неоднородные рыхлые бляшки с высоким содержанием липидов имели высокие показатели индекса усиления при контрастировании – 1,26±0,07, тогда как плотные фиброзные аваскулярные бляшки – 1,09±0,04 (p0,05). Полное время исследования составляло 41±5 мин. при выполнении время-пролетной МР-ангиографии и 29±5 мин. без нее. Сделан вывод, что одновременное проведение МР-ангиографии и контрастной (Mn-парамагнетиком) МР-томографии сонных артерий возможно и целесообразно в рамках единого исследования с использованием квадратурной катушки для головы.
Published: 2016

35. Mononuclear phagocytes of rat liver and lung after intravenous introduction of suspension of magnetite nanoparticles

Author: I. V. Milto, V. Yu. Usov, and I. V. Sukhodolo
Subjects: Gastrointestinal tract, Lung, integumentary system, Lumen (anatomy), Cell Biology, Mononuclear phagocyte system, Metabolism, Biology, Molecular biology, Magnetite Nanoparticles, medicine.anatomical_structure, Total dose, Rat liver, Immunology, medicine
Abstract: Changes in morphology and intraorgan localization of cells of the mononuclear phagocyte system in rat liver and lung are described at various intervals after single and multiple intravenous injection of suspension of unmodified nanoparticles of magnetite (NPM). A possible mechanism is illustrated of elimination of NPM from the rat organism with the participation of mononuclear phagocytes of liver (removal of stellar macrophages into the gastrointestinal tract through bile ducts) and lung (migration of macrophages into the bronchial tree lumen). A possibility is discussed of NPM elimination by different mechanisms, for instance, by metabolism in lysosomes by analogy with transformations of nanoparticles of different qualitative compositions described in the literature. Intravenous administration of NPM has been shown to cause changes in the morphology of rat visceral organs, the expression of these changes being amplified with a rise in the total dose of the introduced magnetite. Nanomagnetite is revealed in rat liver and lung 40 days after single intravenous introduction.
Published: 2012
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36. Phenomenons of microvascular injury in primary myocardial infarction with ST-segment elevation

Author: Ya. V. Alexeeva, Vyacheslav Ryabov, E. V. Vyshlov, R. S. Karpov, V. Yu. Usov, V. A. Markov, and O. V. Mochula
Subjects: business.industry, Medicine, business
Published: 2019
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37. Angular dependence of the pp elastic scattering spin correlation parameter A$_00nn$ between 0.8 and 2.8 GeV: Results for 1.80-2.24 GeV

Author: C. Allgower, J. Ball, L. Barabash, P.-Y. Beauvais, M. Beddo, N. Borisov, A. Boutefnouchet, J. Bystrický, P.-A. Chamouard, M. Combet, Ph. Demierre, J.-M. Fontaine, V. Ghazikhanian, D. Grosnick, R. Hess, Z. Janout, V. Kalinnikov, T. Kasprzyk, Yu. Kazarinov, B. Khachaturov, R. Kunne, F. Lehar, A. de Lesquen, D. Lopiano, M. de Mali, V. Matafonov, I. Pisarev, A. Popov, A. Prokofiev, D. Rapin, J.-L. Sans, H. Spinka, Yu. Usov, V. Vikhrov, B. Vuaridel, C. Whitten, A. Zhdanov, Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), and Robert, Suzanne
Subjects: Elastic scattering, Physics, Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Scattering, [PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex], Particle accelerator, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Kinetic energy, 01 natural sciences, law.invention, Nuclear physics, Transverse plane, Recoil, law, 0103 physical sciences, Physics::Accelerator Physics, Nuclear Experiment, 010306 general physics, Beam (structure), Spin-½
Abstract: Measurements at 19 beam kinetic energies between 1795 and 2235 MeV are reported for the $\mathrm{pp}$ elastic scattering spin correlation parameter ${A}_{00nn}{=A}_{\mathrm{NN}}{=C}_{\mathrm{NN}}.$ The c.m. angular range is typically 60--100\ifmmode^\circ\else\textdegree\fi{}. The measurements were performed at Saturne II with a vertically polarized beam and target (transverse to the beam direction and scattering plane), a magnetic spectrometer and a recoil detector, both instrumented with multiwire proportional chambers, and beam polarimeters. These results are compared to previous data from Saturne II and elsewhere.
Published: 2000

38. ATLAS calorimeter performance

Author: Airapetian, A., Grabsky, V., Hakopian, H., Vartapetian, A., Fares, F., Moorhead, G. F., Sevior, M. E., Taylor, G. N., Tovey, S. N., Alexiev, D., Donnelly, I. J., Varvell, K. E., Williams, M. L., Hashemi-Nezhad, R., Peak, L., Saavedra, A., Ulrichs, J., Girtler, P., Kiener, C., Kneringer, E., Kuhn, D., Rudolph, G., Abdinov, O. B., Aliev, F. M., Khalilzade, F. T., Mekhdiev, R. R., Rzaev, H. J., Usubov, Z. U., Baturitsky, M. A., Bogush, A. A., Demchenko, A. I., Gazizov, A. Z., Gilevsky, V. V., Golubev, V. S., Levchuk, M. I., Satsunkevich, I. S., Shevtsov, V. V., Caloba, L. P., Galvez-Durand, F., Maidantchik, C. L., Marroquin, F., Seixas, J. M., Thome, Z. D., Da Silva, N. C., Dietzsch, O., Leite, M. A. L., Sakanoue, M. H., Takagui, E. M., Zandona, F., Armstrong, W. W., Burris, W., Gingrich, D. M., Hewlett, J. C., Holm, L., Mullin, S., Pinfold, J. L., Schaapman, J., Soukup, J., Wampler, L., Axen, D., Mayer, J. K., Orr, R. S., Armitage, J., Dixit, M., Dubeau, J., Estabrooks, P., Losty, M., Neuheimer, E., Neill, M. O., Oakham, G., Azuelos, G., Ben El Fassi, A., Depommier, P., Leon-Florian, E., Leroy, C., Lorazo, B., P Martin, J., Marullo, F., Pascal Roy, Savard, P., Bailey, D. C., Bhadra, S., Martin, J. F., Sinervo, P. K., Stairs, G. G., Trischuk, W., Astbury, A., Birney, P., Hodges, T., Langstaff, R., Oram, C., Roberts, B., Rosvick, M., Wellisch, H. P., Bishop, S., Fincke-Keeler, M., Honma, A., Keeler, R., Lefebvre, M., Neil, D. O., Poffenberger, P., Robertson, L., Roney, M., Sobie, R., Akesson, T., Anghinolfi, F., Bachy, G., Barberio, E., Benincasa, G., Bergsma, F., Bjorset, L., Blocki, J., Bloess, D., Bock, R., Bogaerts, J., Brawn, I., Burckhart, H. J., Butin, F., Campbell, M., Chesi, E., Chevalley, J. L., Christiansen, J., Cobal, M., Dabrowski, W., Dauvergne, J. P., Acqua, A., Eric Denes, Dittus, F., Dobinson, R., Drakoulakos, D., Dufey, J. P., Eerola, P., Efthymiopoulos, I., Ellis, N., Fabjan, C. W., Farthouat, P., Flegel, W., Francis, D., Froidevaux, D., Gebart, R., Gianotti, F., Gildemeister, O., Hatch, M., Haug, F., Hauviller, C., Heeley, R., Heijne, E., Henriques, A., Hoffmann, H. F., Hortnagl, C., Jarp, S., Jarron, P., Jenni, P., Jones, R., Kantardjian, G., Kaplon, J., Klempt, W., Klyuchnikova, T., Knobloch, J., Koski, K., Kotz, U., Lacasta, C., Langhans, W., Lasseur, C., Lehraus, I., Lemeilleur, F., Lichard, P., Liebhart, M., Linde, F., Lofstedt, B., Madsen, N., Mapelli, L., Marchioro, A., Martin, B., Maugin, J. M., Mclaren, R. A., Meier, D., Michelotto, M., Mornacchi, G., Myers, D., Nessi, M., Nicquevert, B., Onions, C., Patel, A., Poggioli, L., Poppleton, A., Posch, C., Poulard, G., Price, M., Riedler, P., Riegler, W., Roe, S., Rohrbach, F., Rosso, E., Rudge, A., Ryzhov, V., Schaller, M., Schmid, P., Schmitt, M., Schuler, G., Snoeys, W., Spegel, M., Spiwoks, R., Stavrianakou, M., Stavropoulos, G., Tartarelli, F., Ben Taylor, Ten Kate, H., Treichel, M., Tsesmelis, E., Bij, H., Vasey, F., Boehn-Bucholz, R., Voss, R., Vreeswijk, M., Vuillemin, V., Weilhammer, P., Wendler, H., Werner, P., Witzeling, W., Wotschack, J., Bohm, J., Hrivnac, J., Lednicky, R., Lokajicek, M., Nemecek, S., Sicho, P., Simak, V., Stastny, J., Stedron, M., Vanickova, M., Vrba, V., Davidek, T., Dolejsi, J., Dolezal, Z., Kucera, M., Leitner, R., Soustruznik, K., Suk, M., Tas, P., Trka, Z., Valkar, S., Wilhelm, I., Zdrazil, M., Jakubek, J., Kubasta, J., Macha, I., Ota, J., Pospisil, S., Sinor, M., Sopko, B., Tomiak, Z., Dam, M., Hansen, J. D., Hansen, J. R., Hansen, P., Rensch, B., Jalas, P., Schulman, T., Aubert, B., Colas, J., Eynard, G., Jezequel, S., Linossier, O., Massol, N., Minard, M. N., Nicoleau, S., Perrodo, P., Sauvage, G., Wingerter, I., Zitoun, R., Zolnierowski, Y., Ziad Ajaltouni, Badaud, F., Bouhemaid, N., Brette, P., Brossard, M., Chadelas, R., Chevaleyre, J. C., Crouau, M., Daudon, F., Dugne, J. J., Michel, B., Gerard Montarou, S Muanza, G., Pallin, D., Plothow-Besch, H., Poirot, S., Reinmuth, G., Says, L. P., Vazeille, F., Andrieux, M. L., Ballon, J., Collot, J., Daniel Dzahini, Guerre Chaley, B., Hostachy, J. Y., Laborie, G., Martin, P., Pouxe, J., Rabier, C., Rey-Campagnolle, M., Rossetto, O., Saintignon, P., Stassi, P., Wielers, M., Basa, S., Blanquart, L., Bonzom, V., Calzas, A., Chekhtman, A., Clemens, J. C., Cohen-Solal, M., Cousinou, M. C., Dargent, P., Delpierre, P., Dinkespiler, B., Duval, P. Y., Etienne, F., Fallou, A., Fassnacht, P., Ferrato, D., Fouchez, D., Gally, Y., Grigorev, E., Habrard, M. C., Hallewell, G., Le Suu, A., Lilian Martin, Mekkaoui, A., Monnier, E., Mouthuy, T., Nacasch, R., Nagy, E., Olivetto, C., Pouit, L., Qian, Z., Raymond, M., Rondot, C., Rozanov, A., Sauvage, D., Tisserant, S., Touchard, F., Vacavant, L., Ardelean, J., Arnault, C., Auge, E., Barrand, G., Belot, G., Bouchel, M., Boucrot, J., Breton, D., Chollet, C., Coulon, J. P., christophe de La Taille, Delebecque, P., Ducorps, A., Fayard, L., Fournier, D., Gonzales, J., Grivaz, J. F., Hrisoho, A., Iconomidou-Fayard, L., Imbert, P., Jacquier, Y., Jean, P., Lavigne, B., Mace, G., Martin-Chassard, G., Merkel, B., Nikolic, I., Noppe, J. M., Parrour, G., Petroff, P., Puzo, P., Richer, J. P., Schaffer, A. C., Seguin-Moreau, N., Serin, L., Tisserand, V., Togat, V., Unal, G., Vales, F., Veillet, J. J., Vernay, E., Alexanian, H., Baubillier, M., Bezamat, J., Billoir, P., Blouzon, F., Canton, B., David, J., Genat, J. F., Imbault, D., Le Dortz, O., Nayman, P., Rossel, F., Savoy-Navarro, A., Schwemling, P., Belorgey, J., Bernard, R., Berriaud, C., Berthier, R., Borgeaud, P., Bourdinaud, M., Bystricky, J., Calvet, D., Chalifour, M., Chevalier, L., Cloue, O., Dael, A., Delagnes, E., Desages, F., Desportes, H., Ernwein, J., Gachelin, O., Gallet, B., Giacometti, J., Girolamo, P., Gosset, L., Guyot, C., Hansl-Kozanecka, T., Heitzmann, J., Hubbard, J. R., Huet, M., Kozanecki, W., Laporte, J. F., Le Du, P., Lesmond, C., Lottin, J. P., Lugiez, F., Mandzhavidze, I., Mansoulie, B., Mayri, C., Molinie, F., Mur, M., Pabot, Y., Pailler, P., Pascual, J., Pelle, J., Perrin, P., Pinabiau, M., Renardy, J. F., Schuller, J. P., Schune, P., Schwindling, J., Simion, S., Smizanska, M., Taguet, J. P., Teiger, J., Thooris, B., Tirler, R., Hille, H., Veenhof, R., Veyssiere, C., Virchaux, M., Walter, C., Chikovani, L., Gabuniya, L., Gogiberidze, G., Gogoladze, G., Grigalashvili, T., Khorguashvili, Z., Kipiani, K., Koshtoev, V., Sopromadze, D., Topchishvili, L., Tvalashvili, O., Chiladze, B., Dzhobava, T., Khelashvili, A., Zh. Khubua, Liparteliani, A., Metreveli, Z., Mosidze, M., Salukvadze, R., Desch, K., Fischer, P., Geich-Gimbel, C., Hilger, E., Meuser, S., Ockenfels, W., Raith, B., Wermes, N., Becker, C., Fuss, J., Gossling, C., Lisowski, B., Luthaus, P., Wunstorf, R., Bar, T., Jie Chen, Ebling, D. G., Goppert, R., Herten, G., Irsigler, R., Kollefrath, M., Kolpin, R., Landgraf, U., Lauxtermann, S., Ludwig, J., Mohr, W., Paschhoff, V., Rehmann, V., Rolker, B., Runge, K., Schafer, F., Scherberger, G., Schmid, T., Webel, M., Weber, C., Geweniger, C., Hanke, P., Kluge, E. E., Mass, A., Putzer, A., Tittel, K., Wunsch, M., Doersing, V., Erhard, W., Kammel, P., Reinsch, A., Buchholz, P., Hoelldorfer, F., Jakobs, K., Kleinknecht, K., Kopke, L., Marschalkowski, E., Merle, K., Othegraven, R., Renk, B., Schafer, U., Schue, Y., Walkowiak, W., Hoegl, H., Kugel, A., Ludvig, J., Manner, R., Noffz, K. H., Ruehl, S., Zoz, R., Deile, M., Dubbert, J., Faessler, M. A., Hessey, N. P., Sammer, T., Staude, A., Trefzger, T., Ackermann, K., Aderholz, M., Andricek, L., Blum, W., Bratzler, U., Brettel, H., Dietl, H., Dulny, B., Dydak, F., Fent, J., Gruhn, C., Hauff, D., Koffeman, E., Kroha, H., Lutz, G., Manz, A., Moser, H. G., Oberlack, H., Ostapchuk, A., Richter, R., Richter, R. H., Schacht, P., Schael, S., Stenzel, H., Striegel, D., Tribanek, W., Gillessen, G., Holder, M., Kreutz, A., Becks, K. H., Braun, H., Drees, J., Glitza, K. W., Hamacher, K., Kersten, S., Lenzen, G., Linder, C., Middelkamp, P., Wahlen, H., Dris, M., Filippas, A., Fokitis, E., Gazis, E., Katsoufis, E., Maltezos, S., Papadopoulou, T., Giokaris, N., Ioannou, P., Kourkoumelis, C., Papadopoulos, I., Tatsis, S., Tzanakos, G. S., Bouzakis, C., Chardalas, M., Chouridou, S., Dedoussis, S., Gavris, G., Lagouri, T., Liolios, A., Paschalias, P., Petridou, C., Sampsonidis, D., Sergiadis, G., Zamani, M., Dado, S., Goldberg, J., Lupu, N., Abramowicz, H., Alexander, G., Bella, G., Benary, O., Dagan, S., Grunhaus, J., Oren, Y., Breskin, A., Chechik, R., Duchovni, E., Eisenberg, Y., Gross, E., Hass, M., Karshon, U., Lellouch, D., Levinson, L., Mikenberg, G., Revel, D., Arneodo, M., Ayad, R., Capua, M., La Rotonda, L., Liguori, D., Schioppa, M., Susinno, G., Valdata-Nappi, M., Bilokon, H., Chiarella, V., Curatolo, M., Esposito, B., Ferrer, M. L., Maccarrone, G., Pace, E., Pepe-Altarelli, M., Spitalieri, M., Zuffranieri, F., Barberis, D., Bozzo, M., Caso, C., Dameri, M., Darbo, G., Gagliardi, G., Gemme, C., Morettini, P., Musico, P., Olcese, M., Osculati, B., Parodi, F., Pozzo, A., Ridolfi, G., Rossi, L., Sette, G., Cesaroni, F., Creti, P., Gorini, E., Grancagnolo, F., Palamara, O., Panareo, M., Petrera, S., Primavera, M., Battistoni, G., Bellini, G., Bonivento, W., Camin, D., Cavalli, D., Costa, G., Angelo, P. D., Fedyakin, N. N., Anthony Ferrari, Cozzi, L., Labanca, N., Mandelli, L., Mazzanti, M., Menasce, D., Milazzo, L., Moroni, L., Pedrini, D., Perasso, L., Perini, L., Resconi, S., Sala, P., Sala, S., Di Corato, M., Aloisio, A., Alviggi, M. 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D., Angelis, A., Pauletta, G., Santi, L., Scuri, F., Waldner, F., Del Papa, C., Kawaguti, M., Tanaka, S., Asai, M., Iwata, Y., Ohsugi, T., Amako, K., Arai, Y., Fujii, H., Ikeno, M., Iwasaki, H., Kanzaki, J., Kohriki, T., Kondo, T., Manabe, A., Morita, Y., Nomachi, M., Ohska, T. K., Sasaki, O., Sasaki, T., Terada, S., Unno, Y., Watase, Y., Yamamoto, A., Yasu, Y., Kawagoe, K., Nozaki, M., Takeda, H., Takashima, R., Nagamatsu, M., Yoshida, H., Takeshita, T., Hasegawa, Y., Imori, M., Kawamoto, T., Kobayashi, T., Hamatsu, R., Emura, T., Boos, E., Pokrovsky, N., Zhautykov, B., Chakir, H., Cherkaoui, R., Hoummada, A., Saidi, H., Sayouty, E., Bakker, F. E., Bobbink, G. J., Bos, K., Boterenbrood, H., Buis, E. J., Dankers, R. J., Daum, C., Groenstege, H., Hartjes, F., Hendriks, P., Heubers, W., Kaan, B., Kieft, G. N. M., Kluit, R., Massaro, G. G. G., Meddeler, G., Metselaar, J., Rewiersma, P. A. M., Schuijlenburg, H., Spelt, J., Vermeulen, J. 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Z., Ferencei, J., Jusko, A., Kladiva, E., Kubinec, P., Kurca, T., Masarik, J., Povinec, P., Rosinsky, P., Stanicek, J., Stavina, P., Strizenec, P., Sykora, I., Tokar, S., Vanko, J., Cindro, V., Filipcic, A., Kramberger, G., Mikuz, M., Tadel, M., Zontar, D., Blanchot, G., Bosman, M., Bravo, S., Cavalli-Sforza, M., Chmeissani, M., Crespo, J. M., Delfino, M., Fernandez, E., Grauges, E., Yu. Ivanyushenkov, Juste, A., Martinez, M., Miralles, L., Pacheco, A., Park, I. C., Perlas, J. A., Ruiz, H., Vichou, I., Barreiro, F., Del Peso, J., Hervas, L., Labarga, L., Albiol, F., Ballester, F., Benlloch, J. M., Bernabeu, J., Cases, R., Castillo, M. V., Ferrer, A., Fuster, J., Garcia, C., Gonzalez, V., Gil, I., Lopez, J. M., Romance, J. B., Salt, J., Sanchez, J., Sanchis, E., Sanchis, M. 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R., Payne, B. T., Perera, V. J. O., Phillips, P. W., Pilling, A., Quinton, S. P. H., Saunders, B. J., Seller, P., Shah, T. P., Tappern, G. J., Tyndel, M., White, D. J., Wickens, F. J., Booth, C. N., Buttar, C. M., Cartwright, S. L., Combley, F. H., Lehto, M. H., Sellin, P. J., Spooner, N. J. C., Thompson, L. F., Alam, M. S., Athar, S. B., Mahmood, A., Ovunc, S., Severini, H., Timm, S., Wappler, F., Zhichao, L., Berger, E. L., Blair, R., Dawson, J., Guarino, V., Hill, N., May, E. N., Nodulman, L. J., Price, L. E., Proudfoot, J., Schlereth, J. L., Stanek, R., Wagner, R. G., Wicklund, A. B., Cheu, E., Johns, K., Loch, P., Rutherfoord, J., Savin, A., Shaver, L., Shupe, M., Steinberg, J., Tompkins, D., K. De, Gallas, E., Li, J., Sawyer, L., Stephens, R., White, A., Barnett, M., Bintinger, D., Ciocio, A., Dahl, O., Einsweiler, K., Ely, R., Gilchriese, M., Haber, C., Hinchliffe, I., Holland, S., Joshi, A., Kipnis, I., Kleinfelder, S., Milgrome, O., Nygren, D., Palaio, N., Pengg, F., Shapiro, M., Siegrist, J., Spieler, H., Trilling, G., Hazen, E., Shank, J., Simmons, E., Whitaker, J. S., Zhou, B., Behrends, S., Bensinger, J. R., Blocker, C., Cunningham, J., Kirsch, L. E., Lamoureux, J., Wellenstein, H., Citterio, M., Cullen, J., Gibbard, B., Gordeev, A., Gordon, H., Graf, N., Grachev, V., Kandasamy, A., Kotcher, J., Lissauer, D., Ma, H., Makowiecki, D., Murtagh, M. J., Connor, P. O., Paige, F., Polychronakos, V., Protopopescu, S., Radeka, V., Rahm, D. C., Rajagopalan, S., Rescia, S., Smith, G., Sondericker, J., Stephani, D., Stumer, I., Takai, H., Chernyatin, V., Yu, B., Anderson, K., Blucher, E., Evans, H., Glenzinski, D., Merritt, F., Oreglia, M., Pilcher, J., Pod, E., Sanders, H., Shochet, M., Turcot, A., Cartiglia, N., Cunitz, H., Dodd, J., Gara, A., Leltchouk, M., Parsons, J., Seman, M., Shaevitz, M., Sippach, W., Willis, W., Fortney, L. R., Goshaw, A. T., Lee, A. M., Oh, S. H., Robertson, R. J., Wang, C. H., Wesson, D., Baker, K., Feldman, G. J., Franklin, M. E. B., Huth, J., Oliver, J., Hanson, G., Zhenyu Li, Luehring, F., Ogren, H., Rust, D. R., Lankford, A. J., Hackett, C., Pier, S., Schernau, M., Stoker, D., Haridas, P., Osborne, L. S., Paradiso, J. A., Pless, I. A., Taylor, F. E., Wadsworth, B. F., Abolins, M., Brock, R., Bromberg, C., Edmunds, D., Yu. Ermolin, Gross, S., Huston, J., Laurens, P., Linnemann, J., Miller, R., Owen, D., Pope, B. G., Richards, R., Weerts, H., Gold, M., Gorfine, G., Matthews, J., Seidel, S., Khandaker, M., Mcfarlane, K., Punjabi, V., Salgado, C. W., Fortner, M., Sirotenko, V. I., Gutierrez, P., Mcmahon, T., Nemati, B., Skubic, P., Snow, J., Strauss, M., Dressnandt, N., Keener, P., Newcomer, F. M., Berg, R., Williams, H. H., Cleland, W. E., Clemen, M., Bazizi, K., England, D., Ferbel, T., Ginther, G., Glebov, V., Haelen, T., Lobkowicz, F., Slattery, P., Zielinski, M., Dorfan, D., Dubbs, T., Grillo, A., Heusch, C., Kashigin, S., Litke, A., Popelvine, P., Sadrozinski, H. F. W., Seiden, A., Spencer, E., Coan, T. E., Skwarnicki, T., Stroynowski, R., Teplitz, V., Mann, A., Milburn, R., Napier, A., Katrina Sliwa, Downing, R. W., Errede, D., Errede, S., Haney, M. J., Simaitis, V. J., Thaler, J., Burnett, T. H., Chaloupka, V., Cook, V., Daly, C., Davisson, R., Forbush, D., Guldenmann, H., Lubatti, H. J., Mockett, P. M., Reinhall, P., Rothberg, J., Wasserbaech, S., Zhao, T., Fasching, D., Gonzalez, S., Jared, R. C., Pan, Y. B., Scott, I. J., Walsh, J., Wu, S. L., Yamartino, J. M., Zobernig, G., Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ATLAS, and Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)
Subjects: [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]
Published: 1996

39. ATLAS computing technical proposal

Author: Airapetian, A., Grabsky, V., Hakopian, H., Vartapetian, A., Fares, F., Moorhead, G. F., Sevior, M. E., Taylor, G. N., Tovey, S. N., Alexiev, D., Donnelly, I. J., Varvell, K. E., Williams, M. L., Hashemi-Nezhad, R., Peak, L., Saavedra, A., Ulrichs, J., Girtler, P., Kiener, C., Kneringer, E., Kuhn, D., Rudolph, G., Abdinov, O. B., Aliev, F. M., Khalilzade, F. T., Mekhdiev, R. R., Rzaev, H. J., Usubov, Z. U., Baturitsky, M. A., Bogush, A. A., Demchenko, A. I., Gazizov, A. Z., Gilevsky, V. V., Golubev, V. S., Levchuk, M. I., Satsunkevich, I. S., Shevtsov, V. V., Caloba, L. P., Galvez-Durand, F., Maidantchik, C. L., Marroquin, F., Seixas, J. M., Thome, Z. D., Da Silva, N. C., Dietzsch, O., Leite, M. A. L., Sakanoue, M. H., Takagui, E. M., Zandona, F., Armstrong, W. W., Burris, W., Gingrich, D. M., Hewlett, J. C., Holm, L., Mullin, S., Pinfold, J. L., Schaapman, J., Soukup, J., Wampler, L., Axen, D., Mayer, J. K., Orr, R. S., Armitage, J., Dixit, M., Dubeau, J., Estabrooks, P., Losty, M., Neuheimer, E., Neill, M. O., Oakham, G., Azuelos, G., Ben El Fassi, A., Depommier, P., Leon-Florian, E., Leroy, C., Lorazo, B., P Martin, J., Marullo, F., Pascal Roy, Savard, P., Bailey, D. C., Bhadra, S., Martin, J. F., Sinervo, P. K., Stairs, G. G., Trischuk, W., Astbury, A., Birney, P., Hodges, T., Langstaff, R., Oram, C., Roberts, B., Rosvick, M., Wellisch, H. P., Bishop, S., Fincke-Keeler, M., Honma, A., Keeler, R., Lefebvre, M., Neil, D. O., Poffenberger, P., Robertson, L., Roney, M., Sobie, R., Akesson, T., Anghinolfi, F., Bachy, G., Barberio, E., Benincasa, G., Bergsma, F., Bjorset, L., Blocki, J., Bloess, D., Bock, R., Bogaerts, J., Brawn, I., Burckhart, H. J., Butin, F., Campbell, M., Chesi, E., Chevalley, J. L., Christiansen, J., Cobal, M., Dabrowski, W., Dauvergne, J. P., Acqua, A., Eric Denes, Dittus, F., Dobinson, R., Drakoulakos, D., Dufey, J. P., Eerola, P., Efthymiopoulos, I., Ellis, N., Fabjan, C. 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De, Gallas, E., Li, J., Sawyer, L., Stephens, R., White, A., Barnett, M., Bintinger, D., Ciocio, A., Dahl, O., Einsweiler, K., Ely, R., Gilchriese, M., Haber, C., Hinchliffe, I., Holland, S., Joshi, A., Kipnis, I., Kleinfelder, S., Milgrome, O., Nygren, D., Palaio, N., Pengg, F., Shapiro, M., Siegrist, J., Spieler, H., Trilling, G., Hazen, E., Shank, J., Simmons, E., Whitaker, J. S., Zhou, B., Behrends, S., Bensinger, J. R., Blocker, C., Cunningham, J., Kirsch, L. E., Lamoureux, J., Wellenstein, H., Citterio, M., Cullen, J., Gibbard, B., Gordeev, A., Gordon, H., Graf, N., Grachev, V., Kandasamy, A., Kotcher, J., Lissauer, D., Ma, H., Makowiecki, D., Murtagh, M. J., Connor, P. O., Paige, F., Polychronakos, V., Protopopescu, S., Radeka, V., Rahm, D. 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M., Reinhall, P., Rothberg, J., Wasserbaech, S., Zhao, T., Fasching, D., Gonzalez, S., Jared, R. C., Pan, Y. B., Scott, I. J., Walsh, J., Wu, S. L., Yamartino, J. M., Zobernig, G., Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ATLAS, and Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)
Subjects: [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]
Published: 1996

40. Abstracts of articles deposited at viniti

Author: V. L. Mironov, S. I. Tuzova, V. N. Udodov, A. A. Russiyan, N. A. Aleksandrov, L. E. Popov, G. N. Potetyunko, N. Yu. Usov, B. N. Varskoi, N. M. Spasskaya, V. M. Talanov, A. N. Men, M. Sh. Pevzner, V. V. Styrov, V. M. Tolmachev, L. I. Yagnova, R. M. �l'mesov, B. G. Karov, M. S. Bobrovnikov, V. I. Timoshenko, V. V. Fisanov, S. I. Kantorovich, V. E. Domrachev, Yu. I. Paskal, V. A. Chaldyshev, S. N. Grinyaev, S. G. Kataev, V. M. Lisitsyn, L. A. Lisitsyna, V. I. Sigimov, G. A. Gulyazetdinova, E. F. Kondrat'ev, A. V. Pets, R. P. Vasil'eva, V. V. Zubov, N. F. Polunin, V. I. Tereshko, N. N. Byzov, R. V. Gusarova, V. A. Sokolov, Yu. Yu. Vol'fengaut, D. M. Gitman, Sh. M. Shvartsman, V. V. Romanov, V. A. Sigaeva, V. L. Chakhlov, A. M. Antonenko, M. D. Volnyanskii, A. Yu. Kudzin, V. D. Evseev, E. V. Chulkov, V. E. Panin, S. G. Psakh'e, M. F. Zhorovkov, V. N. Sal'nikov, K. P. Aref'ev, A. S. Karetnikov, and G. G. Kravchenko
Subjects: General Physics and Astronomy
Published: 1979
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41. A method of coincidence and anti-coincedence circuit characteristics measurements

Author: V. N. Stibunov, Yu. Usov, V. I. Kryshkin, and N. Fyodorov
Subjects: Physics, Variable (computer science), Optics, business.industry, Resolution (electron density), Detector, Measure (physics), Time resolution, General Medicine, business, Coincidence, Electronic circuit
Abstract: A method is described to measure automatically coincedence and anti-coincedence circuit characteristics by means of a time-to-amplitude converter that allows to obtain resolution curves of circuits apart from time spread in the detectors, to choose easily the time resolution required in a particular experiment and estimate accidental coincedences and efficiency of a circuit obviating the need for any variable delay lines and monitors.
Published: 1972
Full Text: View/download PDF

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