94 results on '"Yu-Sheng Hsiao"'
Search Results
2. Advances in Nanoplasmonic Biosensors: Optimizing Performance for Exosome Detection Applications
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Devi Taufiq Nurrohman, Nan-Fu Chiu, Yu-Sheng Hsiao, Yun-Ju Lai, and Himansu Sekhar Nanda
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surface-plasmon resonance ,localized surface-plasmon resonance ,biosensors ,exosome ,Biotechnology ,TP248.13-248.65 - Abstract
The development of sensitive and specific exosome detection tools is essential because they are believed to provide specific information that is important for early detection, screening, diagnosis, and monitoring of cancer. Among the many detection tools, surface-plasmon resonance (SPR) biosensors are analytical devices that offer advantages in sensitivity and detection speed, thereby making the sample-analysis process faster and more accurate. In addition, the penetration depth of the SPR biosensor, which is
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- 2024
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3. Random and aligned electrospun PLGA nanofibers embedded in microfluidic chips for cancer cell isolation and integration with air foam technology for cell release
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Chia-Cheng Yu, Yi-Wen Chen, Po-Ying Yeh, Yu-Sheng Hsiao, Wei-Ting Lin, Chiung-Wen Kuo, Di-Yen Chueh, Yun-Wen You, Jing-Jong Shyue, Ying-Chih Chang, and Peilin Chen
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Circulating tumor cells ,Poly(lactic-co-glycolic acid) (PLGA) ,Nanofiber arrays ,Air foam ,Biotechnology ,TP248.13-248.65 ,Medical technology ,R855-855.5 - Abstract
Abstract Background Circulating tumor cells (CTCs) comprise the high metastatic potential population of cancer cells in the blood circulation of humans; they have become the established biomarkers for cancer diagnosis, individualized cancer therapy, and cancer development. Technologies for the isolation and recovery of CTCs can be powerful cancer diagnostic tools for liquid biopsies, allowing the identification of malignancies and guiding cancer treatments for precision medicine. Methods We have used an electrospinning process to prepare poly(lactic-co-glycolic acid) (PLGA) nanofibrous arrays in random or aligned orientations on glass slips. We then fabricated poly(methyl methacrylate) (PMMA)-based microfluidic chips embedding the PLGA nanofiber arrays and modified their surfaces through sequential coating with using biotin–(PEG)7–amine through EDC/NHS activation, streptavidin (SA), and biotinylated epithelial-cell adhesion-molecule antibody (biotin-anti-EpCAM) to achieve highly efficient CTC capture. When combined with an air foam technology that induced a high shear stress and, thereby, nondestructive release of the captured cells from the PLGA surfaces, the proposed device system operated with a high cell recovery rate. Results The morphologies and average diameters of the electrospun PLGA nanofibers were characterized using scanning electron microscopy (SEM) and confocal Raman imaging. The surface chemistry of the PLGA nanofibers conjugated with the biotin–(PEG)7–amine was confirmed through time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging. The chip system was studied for the effects of the surface modification density of biotin–(PEG)7–amine, the flow rates, and the diameters of the PLGA nanofibers on the capture efficiency of EpCAM-positive HCT116 cells from the spiked liquid samples. To assess their CTC capture efficiencies in whole blood samples, the aligned and random PLGA nanofiber arrays were tested for their abilities to capture HCT116 cells, providing cancer cell capture efficiencies of 66 and 80%, respectively. With the continuous injection of air foam into the microfluidic devices, the cell release efficiency on the aligned PLGA fibers was 74% (recovery rate: 49%), while it was 90% (recovery rate: 73%) on the random PLGA fibers, from tests of 200 spiked cells in 2 mL of whole blood from healthy individuals. Our study suggests that integrated PMMA microfluidic chips embedding random PLGA nanofiber arrays may be suitable devices for the efficient capture and recovery of CTCs from whole blood samples.
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- 2019
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4. Organic Electrochemical Transistors/SERS-Active Hybrid Biosensors Featuring Gold Nanoparticles Immobilized on Thiol-Functionalized PEDOT Films
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Jia-An Chou, Chieh-Lin Chung, Po-Cheng Ho, Chun-Hao Luo, Yu-Han Tsai, Chung-Kuan Wu, Chiung-Wen Kuo, Yu-Sheng Hsiao, Hsiao-hua Yu, and Peilin Chen
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gold nanoparticles ,poly(3, 4-ethylenedioxythiophene) ,bioelectronic interfaces ,organic electrochemical transistors ,surface-enhanced Raman scattering ,Chemistry ,QD1-999 - Abstract
In this study we immobilized gold nanoparticles (AuNPs) onto thiol-functionalized poly(3,4-ethylenedioxythiophene) (PEDOT) films as bioelectronic interfaces (BEIs) to be integrated into organic electrochemical transistors (OECTs) for effective detection of dopamine (DA) and also as surface-enhanced Raman scattering (SERS)—active substrates for the selective detection of p-cresol (PC) in the presence of multiple interferers. This novel PEDOT-based BEI device platform combined (i) an underlying layer of polystyrenesulfonate-doped PEDOT (PEDOT:PSS), which greatly enhanced the transconductance and sensitivity of OECTs for electrochemical sensing of DA in the presence of other ascorbic acid and uric acid metabolites, as well as amperometric response toward DA with a detection limit (S/N = 3) of 37 nM in the linear range from 50 nM to 100 μM; with (ii) a top interfacial layer of AuNP-immobilized three-dimensional (3D) thiol-functionalized PEDOT, which not only improved the performance of OECTs for detecting DA, due to the signal amplification effect of the AuNPs with high catalytic activity, but also enabled downstream analysis (SERS detection) of PC on the same chip. We demonstrate that PEDOT-based 3D OECT devices decorated with a high-density of AuNPs can display new versatility for the design of next-generation biosensors for point-of-care diagnostics.
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- 2019
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5. Electrochemical Polymerization of PEDOT–Graphene Oxide–Heparin Composite Coating for Anti-Fouling and Anti-Clotting of Cardiovascular Stents
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Ming-Chien Yang, Hui-Ming Tsou, Yu-Sheng Hsiao, Yu-Wei Cheng, Che-Chun Liu, Li-Ying Huang, Xin-Yao Peng, Ting-Yu Liu, Ming-Chi Yung, and Chuan-Chih Hsu
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PEDOT ,electrochemical polymerization ,SUS316L ,biocompatibility ,anti-fouling ,anti-clotting ,Organic chemistry ,QD241-441 - Abstract
In this study, a novel hemocompatible coating on stainless steel substrates was prepared by electrochemically copolymerizing 3,4-ethylenedioxythiophene (EDOT) with graphene oxide (GO), polystyrene sulfonate (PSS), or heparin (HEP) on SUS316L stainless steel, producing an anti-fouling (anti-protein adsorption and anti-platelet adhesion) surface to avoid the restenosis of blood vessels. The negative charges of GO, PSS, and HEP repel negatively charged proteins and platelets to achieve anti-fouling and anti-clotting. The results show that the anti-fouling capability of the poly(3,4-ethylenedioxythiophene) (PEDOT)/PSS coating is similar to that of the PEDOT/HEP coating. The anti-fouling capability of PEDOT/GO is higher than those of PEDOT/HEP and PEDOT/PSS. The reason for this is that GO exhibits negatively charged functional groups (COO−). The highest anti-fouling capability was found with the PEDOT/GO/HEP coating, indicating that electrochemical copolymerization of PEDOT with GO and HEP enhances the anti-fouling capability. Furthermore, the biocompatibility of the PEDOT coatings was tested with 3T3 cells for 1−5 days. The results show that all PEDOT composite coatings exhibited biocompatibility. The blood clotting time (APTT) of PEDOT/GO/HEP was prolonged to 225 s, much longer than the 40 s of pristine SUS316L stainless steel (the control), thus greatly improving the anti-blood-clotting capability of cardiovascular stents.
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- 2019
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6. PEDOT:PSS-Based Bioelectrodes for Multifunctional Drug Release and Electric Cell-Substrate Impedance Sensing
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Yu-Sheng Hsiao, Edgar Daniel Quiñones, Shih-Chieh Yen, Jiashing Yu, Ji-Tseng Fang, Peilin Chen, and Ruey-Shin Juang
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General Materials Science - Published
- 2023
7. The effect of dual-doping on the electrochemical performance of LiNi0.5Mn1.5O4 and its application in full‐cell lithium‐ion batteries
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Shih-Chieh Hsu, Yu-Sheng Hsiao, Cheng-Zhang Lu, Han-Hsin Chiang, Chin-Lung Kuo, Nian-Jheng Wu, Jen-Hsien Huang, Cai-Wan Chang-Jian, Huei Chu Weng, and Chih-Ping Chen
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Process Chemistry and Technology ,Materials Chemistry ,Ceramics and Composites ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials - Published
- 2022
8. Cr-doped LiNi0.5Mn1.5O4 derived from bimetallic Ni/Mn metal-organic framework as high-performance cathode for lithium-ion batteries
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Yu-Sheng Hsiao, Jen-Hsien Huang, Ta-Hung Cheng, Chih-Wei Hu, Nian-Jheng Wu, Chi-Yun Yen, Shih-Chieh Hsu, Huei Chu Weng, and Chih-Ping Chen
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Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology ,Electrical and Electronic Engineering - Published
- 2023
9. A multifunctional ligand for defect passivation of perovskite film realizes air-stable perovskite solar cells with efficiencies exceeding 20%
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Zhong-En Shi, Jian-Yu Long, Chia-Wei Li, Sheng-Yan Hsieh, Yu-Sheng Hsiao, Chih-Ping Chen, and Yuan-Hsiang Yu
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Fuel Technology ,Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology - Abstract
High-performance ambient-stable perovskite solar cells have been obtained after incorporating dtdn and urea into the perovskite. The best device performance featured a power conversion efficiency of 20.64% with excellent air-stability for 720 h.
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- 2022
10. Dual-Gate Enhancement of the Sensitivity of miRNA Detection of a Solution-Gated Field-Effect Transistor Featuring a Graphene Oxide/Graphene Layered Structure
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Chang-Fu Kuo, Sian-Hong Ciou, Chi-Hsien Huang, Ao-Ho Hsieh, Yao-Jen Lee, Tzu-Ting Huang, Yu-Sheng Hsiao, and Wei-Ting Huang
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Materials science ,business.industry ,Graphene ,Oxide ,Dual gate ,Electronic, Optical and Magnetic Materials ,Layered structure ,law.invention ,chemistry.chemical_compound ,chemistry ,law ,Materials Chemistry ,Electrochemistry ,Optoelectronics ,Field-effect transistor ,Sensitivity (control systems) ,business - Published
- 2021
11. Microfluidic device using metallic nanostructure arrays for the isolation, detection, and purification of exosomes
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Yu-Sheng Hsiao, Chun-Wei Chen, Ridhwan Haliq, Pak-Man Yiu, Po-I. Wu, and Jinn P. Chu
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Mechanics of Materials ,Mechanical Engineering ,Materials Chemistry ,Metals and Alloys - Published
- 2023
12. Facile Fabrication of Microwrinkled Poly(3,4-Ethylenedioxythiophene) Films that Promote Neural Differentiation under Electrical Stimulation
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Jiashing Yu, Fang-Jung Chen, Hsueh-Sheng Tseng, I-Hsiang Liao, Yu-Sheng Hsiao, Chih-Ling Lin, and Chun-Ting Liu
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Nervous system ,Fabrication ,Materials science ,Polymers ,Neuronal Outgrowth ,Biomedical Engineering ,Biocompatible Materials ,Stimulation ,Nanotechnology ,PC12 Cells ,Biomaterials ,chemistry.chemical_compound ,Tissue engineering ,Materials Testing ,medicine ,Animals ,Particle Size ,Neural cell ,Electrical conductor ,Conductive polymer ,Biochemistry (medical) ,food and beverages ,Cell Differentiation ,General Chemistry ,Bridged Bicyclo Compounds, Heterocyclic ,Electric Stimulation ,Rats ,medicine.anatomical_structure ,chemistry ,Poly(3,4-ethylenedioxythiophene) - Abstract
Although conductive bioelectronic interfaces (BEIs) can allow neural cell culturing while providing electrical stimulation (ES) to the nervous system, there are few simple approaches for the preparation of conductive BEIs with topographical features designed for cell manipulation. In this study, we developed a facile method for fabricating microwrinkled poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) films through spin-coating onto pre-elongated polydimethylsiloxane substrates. The microwrinkles of our PEDOT:PSS films pre-elongated by 20 and 40% had average widths of 6.47 ± 1.49 and 5.39 ± 1.53 μm, respectively. These microwrinkled PEDOT:PSS films promoted the directional ordering of neurite outgrowth of PC12 cells and displayed favorable biocompatibility and outstanding electrochemical properties for long-term ES treatment. When using this BEI platform, the level of PC12 gene expression of Neun was enhanced significantly after 5 days of culturing in differentiation media and under ES, in line with the decreased expression of early phase markers. Therefore, such readily fabricated microwrinkled PEDOT:PSS films are promising candidates for use as BEIs for tissue regenerative medicine.
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- 2021
13. Sensitive Detection of Sweat Cortisol Using an Organic Electrochemical Transistor Featuring Nanostructured Poly(3,4-Ethylenedioxythiophene) Derivatives in the Channel Layer
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Jayakrishnan Aerathupalathu Janardhanan, Ying-Lin Chen, Chun-Ting Liu, Hsueh-Sheng Tseng, Po-I Wu, Jia-Wei She, Yu-Sheng Hsiao, and Hsiao-hua Yu
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Hydrocortisone ,Polymers ,Reproducibility of Results ,Bridged Bicyclo Compounds, Heterocyclic ,Poly A ,Sweat ,Analytical Chemistry ,Nanostructures - Abstract
In this study, we examined the influence of functionalized poly(3,4-ethylenedioxythiophene) (PEDOT) nanostructures decorated on the channel layer of an organic electrochemical transistor (OECT) for the detection of sweat cortisol, an adrenocorticosteroid stress hormone. The OECT device featured a bilayer channel confined by a PEDOT:polystyrenesulfonate (PSS) underlayer and a nanostructure-decorated upper layer engineered from the monomers EDOT-COOH and EDOT-EG3 through template-free electrochemical polymerization. This molecular design allowed antibody conjugation using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/
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- 2022
14. Phase and morphology control in the synthesis of Co3O4 nanosphere/α-Co(OH)2 nanosheet hybrids for application in supercapacitors
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Jen Hsien Huang, Wei Lin Syu, Cai Wan Chang-Jian, Ying Lin Chen, Yu-Sheng Hsiao, Jia An Chou, Kuen Chan Lee, and Er Chieh Cho
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Supercapacitor ,Materials science ,Polyvinylpyrrolidone ,General Chemical Engineering ,Composite number ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,Capacitance ,0104 chemical sciences ,Chemical engineering ,Reagent ,Phase (matter) ,medicine ,0210 nano-technology ,Nanosheet ,medicine.drug - Abstract
In this study, we developed a facile chemical precipitation approach for the synthesis of heterogeneous Co3O4 nanosphere/Co(OH)2 nanosheet hybrids in the presence of polyvinylpyrrolidone (PVP) as a phase-controlling reagent. The crystalline phase and morphology of the product varied upon changing the chain length of PVP (from 8k to 120k), with short-chain PVP favoring the formation of Co3O4 nanospheres and long-chain PVP favoring the synthesis of Co(OH)2 nanosheets. Accordingly, heterogeneous Co3O4/Co(OH)2 hybrids of various blending ratios were readily prepared in the presence of PVP of different molecular weights. The molecular weight of PVP also affected the electrochemical properties of the Co3O4 nanosphere/Co(OH)2 nanosheet composites. When using PVP of moderate chain length (58k), the resultant Co3O4/Co(OH)2 composite exhibited the optimal supercapacitive performance, characterized by an excellent specific capacitance of 771.2 F g−1 at 1 A g−1, and retained approximately 68.5% of this capacitance when operated at a high current density of 10 A g−1. Furthermore, this composite displayed an excellent charge/discharge cycling life at a current density of 4 A g−1, with a capacitance retention of 93.3% after 3000 repeated cycles.
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- 2020
15. MWCNT-embedded Li4Ti5O12 microspheres interfacially modified with polyaniline as ternary composites for high-performance lithium ion battery anodes
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Kuen Chan Lee, Yu-Sheng Hsiao, Chieh Lin Chung, Jui Hsiung Huang, Cai Wan Chang-Jian, Jia An Chou, Er Chieh Cho, Po Cheng Ho, and Jen Hsien Huang
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010302 applied physics ,Materials science ,Ternary numeral system ,Process Chemistry and Technology ,02 engineering and technology ,Carbon nanotube ,021001 nanoscience & nanotechnology ,01 natural sciences ,Lithium-ion battery ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,law.invention ,chemistry.chemical_compound ,chemistry ,Polymerization ,law ,0103 physical sciences ,Polyaniline ,Materials Chemistry ,Ceramics and Composites ,Surface modification ,Composite material ,In situ polymerization ,0210 nano-technology ,Ternary operation - Abstract
In this study we used a spray-drying process and in situ polymerization to construct ternary composites of Li4Ti5O12 (LTO) embedded with multi-walled carbon nanotubes (MWCNTs) and interfacially modified with polyaniline (PANI). In these composites, the introduced MWCNTs served as conductive backbones within the spray-dried LTO microspheres, thereby lowering the internal resistance of the microcomposites. The polymerized PANI acted as a conductive adhesive to strengthen the interactions between the MWCNTs and the LTO, leading to a sturdier interface and enhanced ionic transport properties. With the combined effects of the embedded MWCNTs and the interfacially polymerized PANI, we observed significant enhancements in both the conductivity and the ionic diffusion kinetics of the LTO composites. As a result, the ternary composites displayed outstanding electrochemical performance, including enhanced rate capability and remarkable cycling stability. The ternary system delivered a discharge capacitance (134.98 mA h/g) at 20 C that was higher than those of bare LTO (38.6 mA h/g) and MWCNT/LTO (114.88 mA h/g). Furthermore, the composites also exhibited 92.7% retention of their specific capacitance after 200 repeated charge/discharge tests, indicating their excellent cycling life.
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- 2020
16. Preparation of porous phosphine oxide-incorporated polymer membranes for selective removal of p-cresol from simulated serum: A preliminary study
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Ruey-Shin Juang, Chu-Chun Chien, Yu-Sheng Hsiao, Hung-Ling Yu, and Chun-Chieh Fu
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Phosphine oxide ,General Chemical Engineering ,Synthetic membrane ,02 engineering and technology ,General Chemistry ,Aliquat 336 ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Chloride ,0104 chemical sciences ,Cellulose triacetate ,chemistry.chemical_compound ,Membrane ,Adsorption ,chemistry ,medicine ,Urea ,0210 nano-technology ,medicine.drug ,Nuclear chemistry - Abstract
This preliminary study aims to prepare porous extractant-incorporated membranes (EIMs) containing base polymer cellulose triacetate (CTA), tri-n-octylphosphine oxide (TOPO), and trioctylammonium chloride (Aliquat 336) prepared by non-solvent induced phase inversion for selective removal of p-cresol from simulated serum. The surface morphology and pore structure of the EIMs were investigated using a field emission scanning electron microscope (FE-SEM) and nitrogen sorptiometer, respectively. The functional groups and chemical composition of the EIMs were characterized by the Fourier transform infrared spectroscopy-attenuated total reflection (FTIR-ATR) and X-ray photoelectron spectrometry (XPS), respectively. The interactions between uremic toxins (p-cresol, creatinine, and urea) and TOPO or Aliquat 336, studied independently by liquid-liquid extraction, were ascribed to hydrogen bonding. Batch tests showed that the addition of TOPO strongly favored p-cresol adsorption; for example, an adsorption capacity of 2.08 mmol/g of the EIM composed of 54.5 wt% CTA, 27.3 wt% Aliquat 336, and 18.2 wt% TOPO was obtained at 37 °C, compared to a negligibly small capacity for creatinine and urea. Cross-flow dynamic experiments revealed that the maximum adsorption of p-cresol in a multi-component serum was 0.75 mmol/g of the EIM under the conditions studied. The high adsorption selectivity for p-cresol may make the prepared EIMs promising and potential for efficient removal of p-cresol from simulated serum.
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- 2020
17. Three-dimensional conductive PEDOT:PSS-based mixed-matrix scaffolds for efficient removal of protein-bound uremic toxins and high-throughput collection of circulating tumor cells
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Yu-Sheng Hsiao, Hsueh-Sheng Tseng, Shih-Chieh Yen, Chuan-Kai Chung, Ji-Tseng Fang, and Ruey-Shin Juang
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General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
18. Lightweight Flexible Polyimide-Derived Laser-Induced Graphenes for High-Performance Thermal Management Applications
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Yu-Sheng Hsiao, Cai-Wan Chang-Jian, Tzu-Yen Huang, Ying-Lin Chen, Chung-Wei Huang, Jen-Hsien Huang, Nian-Jheng Wu, Shih-Chieh Hsu, and Chih Ping Chen
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History ,Polymers and Plastics ,General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2023
19. Rational design of a highly porous electronic scaffold with concurrent enhancement in cell behaviors and differentiation under electrical stimulation
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I-Hsiang Liao, Yu-Sheng Hsiao, Che-Yu Lin, Nai-Chen Cheng, Fang-Jung Chen, Jiashing Yu, Po-I Wu, and Chun-Ting Liu
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Scaffold ,Biomedical Engineering ,Cell Culture Techniques ,Gene Expression ,Biocompatible Materials ,Core Binding Factor Alpha 1 Subunit ,Thiophenes ,PC12 Cells ,Tissue engineering ,PEDOT:PSS ,Osteogenesis ,Animals ,Humans ,General Materials Science ,Conductive polymer ,Chemistry ,Nanotubes, Carbon ,Stem Cells ,Neurogenesis ,Rational design ,Cell Differentiation ,General Chemistry ,General Medicine ,Electric Stimulation ,Rats ,Cell culture ,Biophysics ,Polystyrenes ,Stem cell ,Electronics ,Porosity - Abstract
Conductive polymers (CPs) have received increasing attention as promising materials for studying electrophysiological signals in cell and tissue engineering. The combination of CPs with electrical stimulation (ES) could possibly enhance neurogenesis, osteogenesis, and myogenesis. To date, research has been prioritized on capitalizing CPs as two-dimensional (2D) structures for guiding the differentiation. In contrast, relatively little is conducted on the implementation of 3D conductive scaffolds. In this research, we report the synergic assembly of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) and multi-walled carbon nanotubes (MWCNTs) as a biocompatible, electrically conductive, mechanically robust and structurally porous 3D scaffold. To showcase the bioelectronic utilization, a proof-of-concept demonstration of electrically stimulated cell culture under ES is conducted. The ES effects coupled with the 3D scaffold are promising on pheochromocytoma 12 (PC12), a neuronal cell line, and the ES effect on osteogenesis of human adipose-derived stem cells (hASC) was further studied. PC12 cultured on this PEDOT:PSS/MWCNT 3D scaffolds was induced to differentiate toward a more mature neuronal phenotype with the ES treatment. Furthermore, hASC osteogenesis could be highly promoted in this conductive scaffold with ES. Calcium deposition concentration and osteo-differentiated gene markers were significantly higher with ES. The facile assembly of 3D conductive scaffolds sheds light on both platforms for investigating the 3D microenvironment for electrophysiological simulation of cells and tissues under the ES treatment of in vivo tissue engineering.
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- 2021
20. Surface modification of Ni(OH)2 nanosheets with PEDOT:PSS for supercapacitor and bendable electrochromic applications
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Jen Hsien Huang, Wei Ting Lin, Yu-Sheng Hsiao, Bo Cheng Ho, Cai Wan Chang-Jian, Er Chieh Cho, Kuen Chan Lee, and Jia An Chou
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Supercapacitor ,Chemical resistance ,Materials science ,Renewable Energy, Sustainability and the Environment ,02 engineering and technology ,Conductivity ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,PEDOT:PSS ,Chemical engineering ,Electrochromism ,Surface modification ,0210 nano-technology ,Nanosheet - Abstract
Owing to the chemical resistance, facile production and high electrochemical activity, layered Ni(OH)2 is a useful electrode material for supercapacitors and electrochromic (EC) devices. Nevertheless, the poor electrical conductivity of Ni(OH)2 and its strong tendency to restack during processing have restricted its applications. In this study, we have modified Ni(OH)2 surfaces with a layer of poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) using (3-glycidyloxypropyl)trimethoxysilane (GOPS) as a linker. A nanospace can be created by the conductive layer of PEDOT:PSS wrapped on the Ni(OH)2 nanosheet, which can avoid the reaggregation. Therefore, the Ni(OH)2/PEDOT (P–Ni(OH)2) composites display greater electrochemical activity and kinetics due to the favorable conductivity and interfacial area, suitable for supercapacitor and EC applications. The flexible electrochromic device (ECD) and an asymmetric supercapacitor (AS) incorporating P–Ni(OH)2 are also evaluated in this article. The P–Ni(OH)2 based ECD exhibits superior mechanical stability and the AS also shows excellent cycling stability.
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- 2019
21. Random and aligned electrospun PLGA nanofibers embedded in microfluidic chips for cancer cell isolation and integration with air foam technology for cell release
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Po-Ying Yeh, Yu-Sheng Hsiao, Chia-Cheng Yu, Wei Ting Lin, Di-Yen Chueh, Jing-Jong Shyue, Ying-Chih Chang, Chiung-Wen Kuo, Peilin Chen, Yi-Wen Chen, and Yun-Wen You
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Streptavidin ,Materials science ,Nanofiber arrays ,lcsh:Medical technology ,lcsh:Biotechnology ,Microfluidics ,Population ,Biomedical Engineering ,Nanofibers ,Pharmaceutical Science ,Medicine (miscellaneous) ,Biotin ,Bioengineering ,02 engineering and technology ,Cell Separation ,macromolecular substances ,010402 general chemistry ,01 natural sciences ,Applied Microbiology and Biotechnology ,Polyethylene Glycols ,chemistry.chemical_compound ,Polylactic Acid-Polyglycolic Acid Copolymer ,Cell Line, Tumor ,Lab-On-A-Chip Devices ,lcsh:TP248.13-248.65 ,PEG ratio ,Humans ,education ,education.field_of_study ,Research ,technology, industry, and agriculture ,Circulating tumor cells ,021001 nanoscience & nanotechnology ,Electrospinning ,0104 chemical sciences ,PLGA ,chemistry ,Air foam ,lcsh:R855-855.5 ,Nanofiber ,Molecular Medicine ,Surface modification ,0210 nano-technology ,Poly(lactic-co-glycolic acid) (PLGA) ,Biomedical engineering - Abstract
Background Circulating tumor cells (CTCs) comprise the high metastatic potential population of cancer cells in the blood circulation of humans; they have become the established biomarkers for cancer diagnosis, individualized cancer therapy, and cancer development. Technologies for the isolation and recovery of CTCs can be powerful cancer diagnostic tools for liquid biopsies, allowing the identification of malignancies and guiding cancer treatments for precision medicine. Methods We have used an electrospinning process to prepare poly(lactic-co-glycolic acid) (PLGA) nanofibrous arrays in random or aligned orientations on glass slips. We then fabricated poly(methyl methacrylate) (PMMA)-based microfluidic chips embedding the PLGA nanofiber arrays and modified their surfaces through sequential coating with using biotin–(PEG)7–amine through EDC/NHS activation, streptavidin (SA), and biotinylated epithelial-cell adhesion-molecule antibody (biotin-anti-EpCAM) to achieve highly efficient CTC capture. When combined with an air foam technology that induced a high shear stress and, thereby, nondestructive release of the captured cells from the PLGA surfaces, the proposed device system operated with a high cell recovery rate. Results The morphologies and average diameters of the electrospun PLGA nanofibers were characterized using scanning electron microscopy (SEM) and confocal Raman imaging. The surface chemistry of the PLGA nanofibers conjugated with the biotin–(PEG)7–amine was confirmed through time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging. The chip system was studied for the effects of the surface modification density of biotin–(PEG)7–amine, the flow rates, and the diameters of the PLGA nanofibers on the capture efficiency of EpCAM-positive HCT116 cells from the spiked liquid samples. To assess their CTC capture efficiencies in whole blood samples, the aligned and random PLGA nanofiber arrays were tested for their abilities to capture HCT116 cells, providing cancer cell capture efficiencies of 66 and 80%, respectively. With the continuous injection of air foam into the microfluidic devices, the cell release efficiency on the aligned PLGA fibers was 74% (recovery rate: 49%), while it was 90% (recovery rate: 73%) on the random PLGA fibers, from tests of 200 spiked cells in 2 mL of whole blood from healthy individuals. Our study suggests that integrated PMMA microfluidic chips embedding random PLGA nanofiber arrays may be suitable devices for the efficient capture and recovery of CTCs from whole blood samples. Electronic supplementary material The online version of this article (10.1186/s12951-019-0466-2) contains supplementary material, which is available to authorized users.
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- 2019
22. Spray-drying synthesis of Li4Ti5O12 microspheres in pilot scale using TiO2 nanosheets as starting materials and their application in high-rate lithium ion battery
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Jen Hsien Huang, Er Chieh Cho, Cai Wan Chang-Jian, Bo Cheng Ho, Yu-Sheng Hsiao, Jui Hsiung Huang, Kuen Chan Lee, and Jia An Chou
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Materials science ,Mechanical Engineering ,Spinel ,Metals and Alloys ,02 engineering and technology ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,Lithium-ion battery ,0104 chemical sciences ,Chemical engineering ,Mechanics of Materials ,Impurity ,Phase (matter) ,Spray drying ,Materials Chemistry ,engineering ,Reactivity (chemistry) ,0210 nano-technology ,Nanosheet - Abstract
Spray-drying technique has been widely used for synthesis of energy storage materials due to its low cost and easy scale up. However, in mass production, this method usually suffers from the incomplete solid-state reaction owing to the aggregation or poor reactivity of precursors caused by their large particle size and unfavorable morphology. In this study, spinel Li4Ti5O12 (LTO) has been synthesized by using TiO2 nanosheets as precursor through spray-drying for large-scale production. The TiO2 nanosheets are prepared via a facile and scalable wet grinding method. The high aspect ratio TiO2 nanosheets can efficiently reduce the diffusion length of Li element during the solid-state reaction leading to higher reactivity. It has been found that the temperature required for the formation of LTO phase can be significantly reduced by using the two-dimensional (2D) TiO2 nanosheets as starting materials. As a result, through a pilot-scale spray drying process, the LTO reacted from the TiO2 nanosheets shows a pure spinel structure due to the better morphology of TiO2 nanosheets. In contrast, using the unprocessed TiO2 as precursor, the resulting LTO still reveals other impure phases leading to a poor electrochemical performance. The pure LTO shows a higher discharge capacity of ∼160.8 mAh/g at 0.1 C, with an excellent rate performance and superior cycling life in comparison with the LTO containing impurity phases.
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- 2019
23. Microfluidic organic bioelectronic chips for efficient isolation of trophoblast cells using a combination of rational catenation and electrically controllable refining
- Author
-
Yu-Sheng Hsiao, Shih-Chieh Yen, Po-I Wu, Edgar Daniel Quiñones, Sheng-Ting Hung, Chi-Shuo Chen, and Shih-Ming Tsai
- Subjects
General Materials Science ,Condensed Matter Physics - Published
- 2022
24. Nonsolvent-induced phase separation preparation of porous TOPO-mixed polyethersulfone membranes for selective clearance of p-cresol from simulated serum
- Author
-
Shao-An Chiang, Shou-Hsuan Liu, Yu-Sheng Hsiao, Chun-Chieh Fu, and Ruey-Shin Juang
- Subjects
Filtration and Separation ,Analytical Chemistry - Published
- 2022
25. Doping and surface modification enhance the applicability of Li4Ti5O12 microspheres as high-rate anode materials for lithium ion batteries
- Author
-
Jen Hsien Huang, Chieh-Lin Chung, Jui-Hsiung Huang, Jia-An Chou, Yu-Sheng Hsiao, Bo-Cheng Ho, Chuan-Kai Chung, and Cai-Wan Chang-Jian
- Subjects
Materials science ,Band gap ,Process Chemistry and Technology ,Doping ,Ionic bonding ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Ion ,Anode ,Chemical engineering ,chemistry ,Materials Chemistry ,Ceramics and Composites ,Surface modification ,Ionic conductivity ,Lithium ,0210 nano-technology - Abstract
In this study we prepared Mg2+ and Cr3+ co-doped and phosphidated Li4Ti5O12 (LTO) microspheres using a spray-drying method. Doping with both Mg2+ and Cr3+ improved the electronic conduction of LTO, due to partial reduction of Ti4+ (from Ti4+ to Ti3+) and narrowing of the band gap, respectively. Moreover, the phosphidation process formed a uniform conductive glass layer on the LTO surface, leading to higher ionic conductivity. As a result, the modified LTO exhibited improved rate capability and cyclic stability, compared with those of the pristine LTO. In particular, the Mg2+ and Cr3+ co-doped and phosphidated LTO exhibited superior performance as a result of the combined effects of ion-doping and interfacial modification. Finally, the capacity improved significantly, especially at high C rates [e.g., 127.72 mA h g–1 at 20 C—77.6% of the value recorded at 0.1 C (164.62 mA h g–1)], due to the dual effects of the enhanced electric and ionic conductivities.
- Published
- 2018
26. High-performance supercapacitor based on a ternary nanocomposites of NiO, polyaniline, and Ni/NiO-decorated MWCNTs
- Author
-
Yu-Sheng Hsiao, Cai-Wan Chang-Jian, Tzu-Yen Huang, Ying-Lin Chen, Jen-Hsien Huang, Nian-Jheng Wu, Shih-Chieh Hsu, and Chih-Ping Chen
- Subjects
General Chemical Engineering ,General Chemistry - Published
- 2022
27. Porous cellulose acetate mixed-matrix membrane adsorbents for efficient clearance of p-cresol and creatinine from synthetic serum
- Author
-
Yu-Sheng Hsiao, Hai Nguyen Tran, Jia-Wen Ke, Chun-Chieh Fu, We-Lin Syu, Shou-Hsuan Liu, and Ruey-Shin Juang
- Subjects
General Chemical Engineering ,General Chemistry - Published
- 2022
28. Doping with W6+ ions enhances the performance of TiNb2O7 as an anode material for lithium-ion batteries
- Author
-
Jen Hsien Huang, Han-Hsin Chiang, Xian-Che Jiang, Yu-Sheng Hsiao, Po-I Wu, Cai-Wan Chang-Jian, Cheng-Zhang Lu, Huei Chu Weng, Vanessa K. Peterson, Chih-Ping Chen, and Wei Kong Pang
- Subjects
Materials science ,Doping ,Inorganic chemistry ,General Physics and Astronomy ,chemistry.chemical_element ,Ionic bonding ,Surfaces and Interfaces ,General Chemistry ,Condensed Matter Physics ,Electrochemistry ,Surfaces, Coatings and Films ,Anode ,Ion ,Effective mass (solid-state physics) ,chemistry ,Lithium ,Monoclinic crystal system - Abstract
Monoclinic TiNb2O7 (TNO) has recently been reported as a promising anode candidate for next-generation high-energy–density lithium-ion batteries (LIBs). Unfortunately, poor electronic and ionic conductivities have limited its practical application. In this study, we prepared selectively W6+-doped TNO to overcome these drawbacks. We demonstrate herein the effect of site-selective substitution on the electrochemical performance of TNO after selectively doping its Ti4+ and Nb5+ sites with W6+ ions. The W6+ ions were incorporated into the TNO lattice without dramatically altering the lattice parameters. The ionic substitution of both Ti4+ and Nb5+ ions with W6+ ions in TNO improved the electronic conductivity because of partial reduction of the Ti4+ and Nb5+ ions as a result of charge compensation. Compared with the Nb-substituted TNO (i.e., the TNO derivative in which some of the Nb5+ ions had been replaced by W6+ ions), the Ti-substituted TNO displayed superior transfer properties, presumably because of its lower effective mass. As a result, the Ti-substituted TNO had the highest energy storage performance with its reversible capacity reaching 156.2 mA h/g, even at a rate of 20 C. After 500 repetitive cycles at 6 C, 85.5% of the capacity was retained without significant capacity fading.
- Published
- 2022
29. Microwave-assisted synthesis of TiO2/WS2 heterojunctions with enhanced photocatalytic activity
- Author
-
Cai Wan Chang-Jian, Bo Cheng Ho, Jia Huei Zheng, Yu-Sheng Hsiao, Er Chieh Cho, Kuen Chan Lee, and Jen Hsien Huang
- Subjects
Materials science ,Absorption spectroscopy ,General Chemical Engineering ,Heterojunction ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Hydrothermal circulation ,0104 chemical sciences ,Photocatalysis ,Degradation (geology) ,Irradiation ,0210 nano-technology ,Absorption (electromagnetic radiation) ,Ultraviolet photoelectron spectroscopy - Abstract
In this study, visible light-responsive photocatalysts based on TiO2/WS2 were prepared through a microwave-assisted hydrothermal process. These TiO2/WS2 composites featured a larger surface area and a wider range of optical absorption when compared with those of pure TiO2. Ultraviolet photoelectron spectroscopy revealed that the energy band levels of the heterojunction between the TiO2 and WS2 components were compatible for charge transfer. Compared with pristine TiO2, the photocatalytic activity of the TiO2/WS2 composites was enhanced significantly—the result of expanding the optical absorption spectrum into the visible region as well as decreasing the rate of recombination of the photogenerated electron/hole pairs. The visible photocatalytic activity of the as-prepared photocatalysts was evaluated through the degradation of methylene blue, using a white light emitting diode (LED) as the irradiation source. For the degradation under LED irradiation, the optimal content of WS2 was 3.0 wt%. An examination of the TiO2/WS2 composites in human cells indicated that they were highly biocompatible; they did not affect the cellular proliferation or morphology, suggesting future applications in a biomedical capacity.
- Published
- 2018
30. Thermally conductive polymeric composites incorporating 3D MWCNT/PEDOT:PSS scaffolds
- Author
-
Cai Wan Chang-Jian, Po Yu Chen, Bo Cheng Ho, Jen Hsien Huang, Yu-Sheng Hsiao, Kuen Chan Lee, and Er Chieh Cho
- Subjects
Conductive polymer ,Materials science ,Polydimethylsiloxane ,Mechanical Engineering ,Thermal resistance ,Composite number ,02 engineering and technology ,Carbon nanotube ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Thermal conduction ,01 natural sciences ,Industrial and Manufacturing Engineering ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,Thermal conductivity ,chemistry ,PEDOT:PSS ,Mechanics of Materials ,law ,Ceramics and Composites ,Composite material ,0210 nano-technology - Abstract
Although several types of stabilizers have been investigated recently to disperse carbon nanotubes (CNTs), the most common of them are thermal insulators that increase the thermal resistance and hinder the heat conduction across the CNT junctions. In this study, we dispersed multi-wall carbon nanotubes (MWCNTs) using the conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) as a functional surfactant. Upon sonication, PEDOT:PSS covered the surfaces of the MWCNTs, thereby preventing their π-stacking and increasing their dispersion. Moreover, PEDOT:PSS acted as a thermally conductive bridge that connected the MWCNTs and decreased their thermal resistance. We employed a freeze-drying method to prepare MWCNT/PEDOT:PSS composites with hierarchical microstructures. After introducing polydimethylsiloxane (PDMS) into the MWCNT/PEDOT:PSS foam, the thermal conductivity of the MWCNT/PEDOT:PSS and PDMS composite reached 1.16 W/mK—over 550% higher than that of pure PDMS. These results suggest that such PDMS composites might be useful as thermal interface materials for thermal management in electronic and photonic applications.
- Published
- 2018
31. Clearance of low molecular-weight uremic toxins p-cresol, creatinine, and urea from simulated serum by adsorption
- Author
-
Ruey-Shin Juang, Yu-Sheng Hsiao, Chun-Chieh Fu, Chu-Chun Chien, and Yu-Chin Cheng
- Subjects
Creatinine ,Oxide ,02 engineering and technology ,Porosimetry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,chemistry.chemical_compound ,Adsorption ,chemistry ,Materials Chemistry ,Urea ,medicine ,Freundlich equation ,Physical and Theoretical Chemistry ,p-Cresol ,0210 nano-technology ,Spectroscopy ,Activated carbon ,medicine.drug ,Nuclear chemistry - Abstract
In this study, five adsorbents including activated carbon (AC), three zeolites ZSM-5 with a molar ratio of SiO2 to Al2O3 of 23–400, and graphene oxide (GO) were selected to investigate their abilities for the clearance of three low molecular-weight uremic toxins (p-cresol, creatinine, and urea) from simulated serum at 37 °C. The physicochemical properties of the adsorbents were characterized using the X-ray powder diffractometer and porosimeter. It was found that the adsorption can be followed by the pseudo-second-order kinetic model and the Langmuir equation better fits all adsorption isotherms than the Freundlich equation under the conditions studied. Of the three adsorbents, ZSM5-400 (ZSM-5 with Si/Al = 400) has a maximum adsorption capacity for urea (0.70 mmol/g) and GO has a maximum adsorption capacity for p-cresol (4.01 mmol/g) and creatinine (1.01 mmol/g). To efficiently treat chronic kidney disease patients case by case, the adsorption isotherms of p-cresol and creatinine on the mixed adsorbents was experimentally and theoretically studied to evaluate the possibility of using “tailor-made” adsorbents. The cell viability of the selected adsorbents at different doses for fibroblast NIH/3T3 cells was finally examined.
- Published
- 2018
32. Ternary composite based on homogeneous Ni(OH)2 on graphene with Ag nanoparticles as nanospacers for efficient supercapacitor
- Author
-
Kuen Chan Lee, Yu-Sheng Hsiao, Bo Cheng Ho, Jen Hsien Huang, Er Chieh Cho, Rou Zhen Liu, and Cai Wan Chang-Jian
- Subjects
Supercapacitor ,Materials science ,Graphene ,General Chemical Engineering ,Composite number ,Oxide ,02 engineering and technology ,General Chemistry ,Substrate (electronics) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Capacitance ,Industrial and Manufacturing Engineering ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,law ,Electrode ,Environmental Chemistry ,0210 nano-technology ,Ternary operation - Abstract
In this study, a ternary composite consisting of Ag nanoparticles (NPs) embedded reduced graphene oxide (rGO) and Ni(OH)2 have been synthesized through microwave-assisted reaction. In this system, the rGO serves as conductive substrate to support the Ni(OH)2 and prevent the Ni(OH)2 from restacking. Moreover, the Ag NPs anchored on rGO can create a nanoscale spacers between the rGO/Ni(OH)2 sheets which avoids the π-π interaction between rGO substrates leading to further increase in surface area. In addition, the decoration of Ag NPs also can improve the electrical conductivity of the composites leading to better contact between rGO and Ni(OH)2. As a result of the unique nanoarchitecture, the Ag-rGO/Ni(OH)2 composite exhibits high specific capacitance of 1220 F/g at 1 A/g, which is much higher than that of pristine Ni(OH)2 (588 F/g). Moreover, the ternary composite also shows superior capacitance retention and cycling stability up to 2000 cycles. Asymmetric supercapacitors based on Ag-rGO/Ni(OH)2 electrode and the activated carbon are also assembled. The asymmetric supercapacitors have a maximum energy density of 41.2 Wh/kg at a power density of 375 W/kg with excellent cycling stability. The results indicate the importance of rational design and synthesis of Ag-rGO/Ni(OH)2 for high-performance energy storages.
- Published
- 2018
33. Facile preparation of WO 3 /PEDOT:PSS composite for inkjet printed electrochromic window and its performance for heat shielding
- Author
-
Bo Cheng Ho, Kuen Chan Lee, Er Chieh Cho, Yu-Sheng Hsiao, Cai Wan Chang-Jian, Shih Chieh Yen, and Jen Hsien Huang
- Subjects
Materials science ,Inkwell ,business.industry ,Process Chemistry and Technology ,General Chemical Engineering ,Composite number ,Nanoparticle ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Styrene ,chemistry.chemical_compound ,Sulfonate ,chemistry ,PEDOT:PSS ,Electrochromism ,Optoelectronics ,0210 nano-technology ,business - Abstract
In this study, we have prepared an electrochromic (EC) ink composed of WO 3 nanoparticles and poly (3,4-ethylenedioxythiophene):poly (styrene sulfonate) (PEDOT:PSS). The ink formulation can be processed through inkjet-printing or spray coating to deposit high-quality EC layers. The PEDOT:PSS acts as an conductive binder to connect the WO 3 nanoparticles leading to reduced impedance and better electrochemical properties. The WO 3 /PEDOT:PSS (PH1000) exhibits an optical modulation of 54.1%, a response time of 1.1 s, and a coloration efficiency of 83.87 cm 2 /C. A hybrid type electrochromic device (ECD) incorporated with WO 3 /PEDOT:PSS with excellent durability has been fabricated. The performance of WO 3 /PEDOT:PSS based ECD for sun shielding property is also evaluated. The ECD can efficiently block the sunlight and reduce solar heat gain. As a result, the indoor temperature can be modulated from 32.7 °C (bleached state) to 29.4 °C (darken state) under illumination.
- Published
- 2018
34. Design and fabrication of electrospun mixed-matrix multi-layered membranes containing tri-n-octylphosphine oxide for efficient adsorption of p-cresol
- Author
-
Shou-Hsuan Liu, Yu-Sheng Hsiao, Sheng-Chuan Wang, Ruey-Shin Juang, and Chun-Chieh Fu
- Subjects
chemistry.chemical_compound ,Cellulose triacetate ,Colloid and Surface Chemistry ,Membrane ,Morphology (linguistics) ,Adsorption ,Fabrication ,Chemical engineering ,Chemistry ,Oxide ,p-Cresol ,Electrospinning - Abstract
In this study, various types of mixed-matrix cellulose triacetate (CTA) fibrous membranes were prepared by a combined electrospinning and electrospraying process, in which tri-n-octylphosphine oxide (TOPO) powders were incorporated on the surface of the fibers to remove uremic toxin p-cresol by adsorption. The morphology, chemical composition (element analysis), and textural properties of the prepared fibrous membranes were first analyzed. The adsorption ability of various fibrous membranes for p-cresol in synthetic serum was then studied in batch experiments at pH 7.4 and 37 °C. It was seen that the loose structure of the electrospun fibrous membranes was beneficial to the rate of adsorption and the position where the TOPO stayed on the fibers played a crucial role in the availability of TOPO and hence the adsorption performance. The maximum adsorption of p-cresol was 6.45 mmol per gram of TOPO, highlighting the adsorption ability of as-prepared mixed-matrix membranes. Moreover, the electrospun TOPO-coated fibers covered with a thin layer of the electrospun CTA fibers largely improved cell viability. The present results have demonstrated the application potential of electrospun/sprayed mixed-matrix fibrous membranes with TOPO for efficient adsorption of p-cresol.
- Published
- 2021
35. The effect of wetting property on electrochromic properties offunctionalized poly(3,4-ethylenedioxythiophene) films
- Author
-
Yu-Sheng Hsiao, Cheng Chia Yu, Jen Hsien Huang, Bo Cheng Ho, Cai Wan Chang-Jian, Er Chieh Cho, and Kuen Chan Lee
- Subjects
Materials science ,Process Chemistry and Technology ,General Chemical Engineering ,Ionic bonding ,02 engineering and technology ,Electrolyte ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Contact angle ,chemistry.chemical_compound ,chemistry ,PEDOT:PSS ,Chemical engineering ,Electrochromism ,Organic chemistry ,Wetting ,0210 nano-technology ,Poly(3,4-ethylenedioxythiophene) - Abstract
We have prepared three poly(3,4-ethylenedioxythiophene) (PEDOT) derivatives including PEDOT, hydroxymethyl PEDOT (PEDOT-OH) and perfluoro-substituted PEDOT (PEDOT-F), along with its electrochemical and electrochromic (EC) characterization. The three PEDOT derivatives have variable degree of wettability; which have been compared systematically to investigate the effect of moisture on EC property. The bulky substituents lead to large inter-chain separation and facilitate the movement of counter ions leading to better ionic transport. Furthermore, with perfluoro-functionalized side groups, the PEDOT-F exhibits a water contact angle of 134.7°, significantly higher than that of PEDOT (57.8°), clearly indicating its hydrophobic property. This hydrophobic property of PEDOT-F can prevent it from damage by water within the electrolyte during redox reaction. Combining the advantages of better ionic transport and moisture resistance, the PEDOT-F reveals a better EC lifetime.
- Published
- 2017
36. High-performance, robust, stretchable organic photovoltaics using commercially available tape as a deformable substrate
- Author
-
Chih-Ping Chen, Yu-Sheng Hsiao, Chun-Ying Chiang, Yang-Yen Yu, and Wen-Chang Chen
- Subjects
Materials science ,Organic solar cell ,Renewable Energy, Sustainability and the Environment ,business.industry ,Photovoltaic system ,Energy conversion efficiency ,Wearable computer ,Nanotechnology ,02 engineering and technology ,Substrate (printing) ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Electric power system ,Optoelectronics ,0210 nano-technology ,business ,Sensing system ,Wearable technology - Abstract
Electronic skins and smart textiles are emerging applications integrating wearable displays, smart sensing systems, health-care monitors, and stretchable power systems. Although various deformable optoelectronic devices have been demonstrated, high-performance stretchable photovoltaic (PV) devices remain a significant challenge in device engineering and materials optimization. In this paper, we demonstrate how a ubiquitous material—3 M™ tape—can be used as a transparent substrate for highly efficient stretchable organic PV devices. Indeed, we constructed a stretchable OPV device displaying a power conversion efficiency (PCE) of 5.2% (under AM 1.5G 1000 W m −2 )—the highest reported to date; in addition, this device retained 80% of its original PCE after 50 cycles of stretching at 20% strain. This study paves the way toward fully deformable OPVs for integration in wearable electronics.
- Published
- 2017
37. Robust multifunctional superhydrophobic coatings with enhanced water/oil separation, self-cleaning, anti-corrosion, and anti-biological adhesion
- Author
-
Kao Shuh Chuang, Cai Wan Chang-Jian, Jen Hsien Huang, Er Chieh Cho, Hsin Chou Chen, Kuen Chan Lee, Yu-Sheng Hsiao, and Jia Huei Zheng
- Subjects
Nanocomposite ,Materials science ,Biological adhesion ,General Chemical Engineering ,Composite number ,Anti-corrosion ,Nanoparticle ,Nanotechnology ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Industrial and Manufacturing Engineering ,Superhydrophobic coating ,0104 chemical sciences ,Contact angle ,chemistry.chemical_compound ,chemistry ,Siloxane ,Environmental Chemistry ,0210 nano-technology - Abstract
In this study, superhydrophobic and transparent siloxane-based nanocomposites have been synthesized. The as-synthesized superhydrophobic nanoparticles reveal uniform particle size distribution and high dispersibility in alcohol solvents which can be easily integrated into solution-process. Further improvement of superhydrophobicity of this composite is achieved by the chemical modification with fluorosilane. The cast hybrid surface reveals superhydrophobic (water contact angle (WCA) = 168°), non-stick and transparent properties (90% at 550 nm) on a variety of substrates. As a result, the as-prepared superhydrophobic coating shows outstanding water/oil separation, self-cleaning, anti-corrosion and anti-adhesion of bacteria and algae. Moreover, the superhydrophobic coating can remain its extreme water repellency without obvious decay of WCA after weathering resistance test for 90 days. It is believed that the facile and low-cost method offers an effective strategy and promising industrial applications for fabricating superhydrophobic surfaces.
- Published
- 2017
38. Self-assembled coronene nanofiber arrays: toward integrated organic bioelectronics for efficient isolation, detection, and recovery of cancer cells
- Author
-
Yu-Sheng Hsiao, Rou-Zhen Liu, and Po-Jung Chen
- Subjects
Organic electronics ,Bioelectronics ,Materials science ,General Chemical Engineering ,Microfluidics ,Nanotechnology ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Potentiostat ,0104 chemical sciences ,Circulating tumor cell ,Nanofiber ,Electrode ,Cyclic voltammetry ,0210 nano-technology - Abstract
The biological immobilization of antibodies onto geometrically controlled conducting/semiconducting nanostructures is a promising approach for directing efficient cell–substrate interactions at bioelectronic interfaces (BEIs), thereby facilitating the melding of biological systems with electronics. In this study, we employed a novel thin-film growth technology to fabricate three-dimensional (3D) organic small-molecule semiconductor-based nanofiber (NF) arrays on transparent conducting electrodes, and examined their BEI integration for the isolation, detection, and recovery of circulating tumor cells (CTCs). During normal thermal evaporation, out-of-plane nanostructures of coronene (CR), a polycyclic aromatic small molecule, readily formed through template-assisted self-assembly. We exploited the synergistic effects of controllable CR-based NF structures and anti-epithelial cellular adhesion molecule (anti-EpCAM) coatings as nanovelcro cell-affinity assays to enhance the capture efficiency of targeted CTCs, while behaving as anti-adhesive surfaces for non-targeted cells. Because of the high integration capability and high optical transparency of CR-based NFs, optimizing the binding conditions of the anti-EpCAM coatings allowed us to develop a liquid biopsy chip for the selective capture of CTCs and for the rapid/direct quantification (using a normal inverted optical microscope) of the number of captured CTCs; in addition, we designed this system such that it would allow electrically driven cell-release (using an electrochemical potentiostat). The desorption phenomena of PLL-g-PEG–biotin upon applying 20 cycles of cyclic voltammetry (voltage swept from 0 to +1.0 V) in PBS buffer triggered the electrical release of the captured CTCs from the CR-based NFs; integration of the CR-based NF substrate with an overlaid microfluidic PDMS chaotic mixer led to highly efficient cell-capture yields (>84%) at various spiked densities of MCF7 cells in a THP-1 cell solution (106 cells per mL); over 90% of the resulting cells were viable. These 3D CR-based BEI devices suggest that new opportunities abound in the design of novel organic electronics for advanced biomedical applications.
- Published
- 2017
39. Carbon Nanotube/Conducting Polymer Hybrid Nanofibers as Novel Organic Bioelectronic Interfaces for Efficient Removal of Protein-Bound Uremic Toxins
- Author
-
Chi-Hsien Huang, Ruey-Shin Juang, Yu-Sheng Hsiao, Shih-Chieh Yen, Peilin Chen, Zhao-Wei Liu, Ji-Tseng Fang, and Sravani Sahoo
- Subjects
Materials science ,Low protein ,Polymers ,02 engineering and technology ,Carbon nanotube ,010402 general chemistry ,01 natural sciences ,law.invention ,Cresols ,PEDOT:PSS ,law ,Renal Dialysis ,Humans ,General Materials Science ,Toxins, Biological ,Uremia ,Conductive polymer ,Nanotubes, Carbon ,Hippurates ,Proteins ,Adhesion ,021001 nanoscience & nanotechnology ,Electrospinning ,0104 chemical sciences ,Membrane ,Chemical engineering ,Nanofiber ,Adsorption ,Electronics ,0210 nano-technology ,Indican - Abstract
Protein-bound uremic toxins (PBUTs) can cause noxious effects in patients suffering from renal failure as a result of inhibiting the transport of proteins and inducing their structural modification. They are difficult to remove through standard hemodialysis (HD) treatment. Herein, we report an organic bioelectronic HD device system for the effective removal of PBUTs through electrically triggered dissociation of protein-toxin complexes. To prepare this system, we employed electrospinning to fabricate electrically conductive quaternary composite nanofiber mats-comprising multiwalled carbon nanotubes (MWCNTs), poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS), poly(ethylene oxide) (PEO), and (3-glycidyloxypropyl)trimethoxysilane (GOPS)-on conventional polyethersulfone (PES) dialysis membranes. These composite nanofiber platforms exhibited (i) long-term water resistance (due to cross-linking among PSS, PEO, and GOPS), (ii) high adhesion strength on the PES membrane (due to GOPS functioning as an adhesion promoter), (iii) enhanced electrical properties [due to the MWCNTs and PEDOT:PSS promoting effective electrical stimulation (ES) operation in devices containing bioelectronic interfaces (BEI)], and (iv) good anticoagulant ability and negligible hemolysis of red blood cells. We employed this organic BEI electronic system as a novel single-membrane HD device to study the removal efficiency of four kinds of uremic toxins [p-cresol (PC), indoxyl sulfate, and hippuric acid as PBUTs; creatinine as a non-PBUT] as well as the effects of ES on lowering the protein binding ratio. Our organic BEI devices provided a high rate of removal of PC with low protein loss after 4 h of a simulated dialysis process. It also functioned with low complement activation, low contact activation levels, and lower amounts of platelet adsorption, suggesting great suitability for use in developing next-generation bioelectronic medicines for HD.
- Published
- 2019
40. Organic Electrochemical Transistors/SERS-Active Hybrid Biosensors Featuring Gold Nanoparticles Immobilized on Thiol-Functionalized PEDOT Films
- Author
-
Hsiao-hua Yu, Jia-An Chou, Chiung-Wen Kuo, Chieh-Lin Chung, Chun-Hao Luo, Peilin Chen, Yu-Sheng Hsiao, Po-Cheng Ho, Yu-Han Tsai, and Chung-Kuan Wu
- Subjects
surface-enhanced Raman scattering ,Materials science ,Nanotechnology ,02 engineering and technology ,poly(3, 4-ethylenedioxythiophene) ,010402 general chemistry ,Electrochemistry ,01 natural sciences ,lcsh:Chemistry ,chemistry.chemical_compound ,PEDOT:PSS ,Original Research ,Detection limit ,General Chemistry ,021001 nanoscience & nanotechnology ,Ascorbic acid ,organic electrochemical transistors ,Amperometry ,0104 chemical sciences ,bioelectronic interfaces ,Chemistry ,chemistry ,lcsh:QD1-999 ,Colloidal gold ,gold nanoparticles ,0210 nano-technology ,Biosensor ,Poly(3,4-ethylenedioxythiophene) - Abstract
In this study we immobilized gold nanoparticles (AuNPs) onto thiol-functionalized poly(3,4-ethylenedioxythiophene) (PEDOT) films as bioelectronic interfaces (BEIs) to be integrated into organic electrochemical transistors (OECTs) for effective detection of dopamine (DA) and also as surface-enhanced Raman scattering (SERS)-active substrates for the selective detection of p-cresol (PC) in the presence of multiple interferers. This novel PEDOT-based BEI device platform combined (i) an underlying layer of polystyrenesulfonate-doped PEDOT (PEDOT:PSS), which greatly enhanced the transconductance and sensitivity of OECTs for electrochemical sensing of DA in the presence of other ascorbic acid and uric acid metabolites, as well as amperometric response toward DA with a detection limit (S/N = 3) of 37 nM in the linear range from 50 nM to 100 μM; with (ii) a top interfacial layer of AuNP-immobilized three-dimensional (3D) thiol-functionalized PEDOT, which not only improved the performance of OECTs for detecting DA, due to the signal amplification effect of the AuNPs with high catalytic activity, but also enabled downstream analysis (SERS detection) of PC on the same chip. We demonstrate that PEDOT-based 3D OECT devices decorated with a high-density of AuNPs can display new versatility for the design of next-generation biosensors for point-of-care diagnostics.
- Published
- 2019
41. Enhanced electrochromic performance of carbon-coated V2O5 derived from a metal–organic framework
- Author
-
Huei-Chu Weng, Shih-Chieh Hsu, Cai-Wan Chang-Jian, Yu-Sheng Hsiao, Shih-Chieh Yen, Cheng-Zhang Lu, Wei-Lin Syu, and Jen Hsien Huang
- Subjects
Materials science ,General Physics and Astronomy ,Vanadium ,chemistry.chemical_element ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,Quartz crystal microbalance ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,PEDOT:PSS ,Coating ,chemistry ,Chemical engineering ,Electrochromism ,Electrode ,engineering ,Metal-organic framework ,0210 nano-technology - Abstract
In this study we synthesized a vanadium (V)-containing metal–organic framework (MOF) and used it as a template to prepare V2O5 NPs. We used MIL-47, a V-containing MOF having uniform C and V distributions, as a precursor for the preparation of carbon-coated V2O5 (C@V2O5) samples through annealing. The C@V2O5 structures were readily dispersed in poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) to form stable solutions, allowing the deposition of C@V2O5 on various substrates through simple low-temperature solution-based processes. The uniform coating of carbon on V2O5 was useful for two reasons: (i) the outer layer enhanced the electronic conductivity of a V2O5 electrode and its corresponding electrochemical properties and (ii) based on the electrochemical quartz crystal microbalance (EQCM) analysis, the carbon coating served as a buffer layer that allowed Li+ ion transport, but blocked migration of solvent into the V2O5 electrode, thereby improving the dimensional and electrochemical stability. Compared with the bare V2O5, C@V2O5 exhibited excellent electrochromic (EC) performance, with an EC contrast of 45.8%, a mean response time of 3.4 s, and a coloration efficiency of 89.3 cm2/C. C@V2O5 also displayed higher cycling stability (80.6% retention after 5000 cycles) and highly reversible ionic transport during redox reactions, compared with those of the bare V2O5.
- Published
- 2021
42. High-performance Li-Ion capacitor constructed from biomass-derived porous carbon and high-rate Li4Ti5O12
- Author
-
Yan-Ting Lin, Chih-Ping Chen, Wei-Lin Syu, Cai-Wan Chang-Jian, Huei Chu Weng, Yu-Sheng Hsiao, Jen Hsien Huang, and Tzu-Hsien Hsieh
- Subjects
Supercapacitor ,Materials science ,General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Cathode ,0104 chemical sciences ,Surfaces, Coatings and Films ,law.invention ,Anode ,Surface coating ,Chemical engineering ,chemistry ,law ,Lithium-ion capacitor ,0210 nano-technology ,Mesoporous material ,Pyrolysis ,Carbon - Abstract
In this study we prepared a biomass-derived porous carbon and a high-rate Li4Ti5O12 (LTO) as cathode and anode materials, respectively, for Li-ion capacitors (LICs). We synthesized the bio-derived carbon through pyrolysis of rubberwood as the carbon source. The as-synthesized carbon featured a hierarchical micro/mesoporous architecture with a surface area of 1365 m2 g−1 and excellent electrochemical properties. A symmetric supercapacitor (SC) based on the bio-derived carbon material exhibited excellent capacitance characteristics and remarkable cycling stability. Furthermore, the rate performance of the spray-dried LTO modified through ionic doping and surface coating was much better than that of the unmodified LTO, due to enhanced conductivity and ionic diffusivity. Because of the outstanding rate capability of the modified LTO, the kinetic mismatch between the cathode and anode—a general problem for LICs—was overcome. After coupling the bio-derived porous carbon with the high-rate LTO, the as-fabricated LIC displayed a high energy/power density of 142 Wh kg−1/253 W kg−1, and even provided a value of 52.9 Wh kg−1 at 4556 W kg−1. In addition, this LIC retained 85.7% of its original capacity after 10,000 cycles.
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- 2021
43. Dual-Gate Enhancement of the Sensitivity of miRNA Detection of a Solution-Gated Field-Effect Transistor Featuring a Graphene Oxide/Graphene Layered Structure.
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Chi-Hsien Huang, Wei-Ting Huang, Tzu-Ting Huang, Sian-Hong Ciou, Chang-Fu Kuo, Ao-Ho Hsieh, Yu-Sheng Hsiao, and Yao-Jen Lee
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- 2021
- Full Text
- View/download PDF
44. Co2+-Doped BiOBrxCl1-x hierarchical microspheres display enhanced visible-light photocatalytic performance in the degradation of rhodamine B and antibiotics and the inactivation of E. coli
- Author
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Guang Yu Lee, Kuen Chan Lee, Ming Yen Sung, Yu-Sheng Hsiao, Chih-Ping Chen, Huei Chu Weng, Jen Hsien Huang, Er Chieh Cho, Cai Wan Chang-Jian, Wei Lin Syu, and Wei Hung Hung
- Subjects
Environmental Engineering ,Materials science ,Biocompatibility ,Health, Toxicology and Mutagenesis ,Doping ,Photochemistry ,Pollution ,chemistry.chemical_compound ,symbols.namesake ,chemistry ,Nanocrystal ,Rhodamine B ,Photocatalysis ,symbols ,Environmental Chemistry ,Degradation (geology) ,Photodegradation ,Raman spectroscopy ,Waste Management and Disposal - Abstract
In this article, we have synthesized Co2+-doped BiOBrxCl1-x hierarchical nanostructured microspheres, featuring different degrees of Co2+ doping, displaying excellent photocatalytic performance. X-ray diffraction and Raman spectroscopy indicated that the Co2+ ions were successfully doped into the BiOBrxCl1-x nanocrystals. The photodegradation rate of rhodamine B mediated by a doped BiOBrxCl1-x was 150 % greater than that of the non-doped BiOBr. We ascribe the improved photocatalytic capability of the Co2+-doped BiOBrxCl1-x to a combination of its superior degree of light absorption, more efficient carrier separation, and faster interfacial charge migration. The major active species involved in the photodegradation of RhB also has been investigated. Moreover, the doped BiOBrxCl1-x possessed excellent cellular biocompatibility and displayed remarkable performance in the photocatalytic bacterial inactivation.
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- 2021
45. Three-dimensional carbon nanotube based polymer composites for thermal management
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Cai Wan Chang-Jian, Kuen Chan Lee, Er Chieh Cho, Jen Hsien Huang, and Yu-Sheng Hsiao
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Materials science ,Polydimethylsiloxane ,Composite number ,Modulus ,02 engineering and technology ,Carbon nanotube ,Heat sink ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,Thermal conductivity ,chemistry ,Mechanics of Materials ,law ,Thermal ,Ceramics and Composites ,Composite material ,0210 nano-technology ,Porosity - Abstract
In this study, the porous multiwall carbon nanotube (MWCNT) foams possessing three-dimensional (3D) scaffold structures have been introduced into polydimethylsiloxane (PDMS) for enhancing the overall thermal conductivity (TC). This unique interconnected structure of freeze-dried MWCNT foams can provide thermally conductive pathways leading to higher TC. The TC of 3D MWCNT and PDMS composites can reach 0.82 W/m K, which is about 455% that of pure PDMS, and 300% higher than that of composites prepared from traditional blending process. The obtained polymer composites not only exhibit superior mechanical properties but also dimensional stability. To evaluate the performance of thermal management, the LED modulus incorporated with the 3D MWCNT/PDMS composite as heat sink is also fabricated. The composites display much faster and higher temperature rise than the pristine PDMS matrix, suggestive of its better thermal dissipation. These results imply that the as-developed 3D-MWCNT/PDMS composite can be a good candidate in thermal interface for thermal management of electronic devices.
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- 2016
46. Interfacial engineering of melamine sponges using hydrophobic TiO 2 nanoparticles for effective oil/water separation
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Kuen Chan Lee, Jen Hsien Huang, Er Chieh Cho, Cai Wan Chang-Jian, and Yu-Sheng Hsiao
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Materials science ,biology ,General Chemical Engineering ,Nanoparticle ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,biology.organism_classification ,01 natural sciences ,0104 chemical sciences ,Sponge ,Oleic acid ,chemistry.chemical_compound ,Adsorption ,Chemical engineering ,chemistry ,Trifluoroacetic acid ,Organic chemistry ,Wetting ,0210 nano-technology ,Melamine ,Selectivity - Abstract
In this study, the surface modified TiO 2 nanoparticles have been synthesized with oleic acid and trifluoroacetic acid (TFAA) as surfactants. The as-prepared TiO 2 nanoparticles reveal small particle size with narrow distribution, excellent dispersibility and high hydrophobicity. By interfacial modifying the melamine sponge with the hydrophobic TiO 2 nanoparticle, the wettability of the modified sponge can be tailored to be superhydrophobic to water while superoleophilic to oils. Combining with the porous structure of melamine sponge and the excellent hydrophobicity of the coated TiO 2 , the modified sponge exhibits large absorption capacity (up to 88.1 g/g for chloroform), good selectivity and high recyclability for a wide range of oils and organic solvents. The results indicate that the TiO 2 modified sponges may potentially be useful as next-generation oil adsorbent materials.
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- 2016
47. Graphene-based thermoplastic composites and their application for LED thermal management
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Yu-Sheng Hsiao, Jen Hsien Huang, Er Chieh Cho, Chiu Ping Li, Kuen Chan Lee, Cai Wan Chang-Jian, and Jui Hsiung Huang
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Nanocomposite ,Materials science ,Graphene ,Composite number ,Oxide ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Titanate ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,Thermal conductivity ,chemistry ,law ,Polyamide ,Molecule ,General Materials Science ,Composite material ,0210 nano-technology - Abstract
In this article, the polyamide (PA)/reduced graphene (rGO) nanocomposites used for thermally conductive materials have been synthesized through melting blending. A titanate coupling agent (TCA) is used to modify the rGO to enhance the chemical compatibility between rGO and PA. The results suggest that the covalent bonds can be formed by the chemical reaction between alkoxy group of titanate molecules and hydroxyl groups on the graphene oxide (GO). With the interfacial modification, the rGO can be dispersed well within the PA matrix. Moreover, the TCA molecule can replace of water of hydration at the rGO surface, which can eliminate the air voids within the composites resulting in better thermal conductivity. The LED lamp incorporated with the rGO based composite as heat sink also display better durability due to its excellent thermal dissipation.
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- 2016
48. Influence of the bridging atom on the electrochromic performance of a cyclopentadithiophene polymer
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Yu-Sheng Hsiao, Jen Hsien Huang, Cai Wan Chang-Jian, Er Chieh Cho, and Kuen Chan Lee
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chemistry.chemical_classification ,Materials science ,Silicon ,Renewable Energy, Sustainability and the Environment ,Stacking ,chemistry.chemical_element ,02 engineering and technology ,Polymer ,Conjugated system ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Crystallography ,Crystallinity ,chemistry ,Electrochromism ,Transmittance ,Organic chemistry ,Thermal stability ,0210 nano-technology - Abstract
In this article, carbon- (PCPDTTBT) and silicon-bridged (PSiPDTTBT) cyclopentadithiophene (CPDT)-based polymers have been synthesized. We have systematically studied the effect of replacing a carbon atom with a silicon atom on the main chain of the conjugated polymer and the optoelectronic properties. With the simple substitution, the results indicate that the PSiPDTTBT reveals a higher crystallinity, improved thermal stability, charge transport properties, and lower resistance at the polymer-electrolyte interface. As a result, the PSiPDTTBT exhibits better electrochromic properties including higher contrast and coloration efficiency (CE) with respect to its carbon analogs. We attribute this better electrochromic performance to the presence of strong π–π stacking in the silicon-bridged CPDT-based polymer. The PSiPDTTBT shows a transmittance window of 55.5% at 560 nm and CE of 434 mC/cm 2 .
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- 2016
49. Adsorptive removal of p-cresol and creatinine from simulated serum using porous polyethersulfone mixed-matrix membranes
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Shou-Hsuan Liu, Jia-Wen Ke, Ruey-Shin Juang, We-Lin Syu, Yu-Sheng Hsiao, Chun-Chieh Fu, and Ting-Yu Liu
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Langmuir ,Chemistry ,Oxide ,Filtration and Separation ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Analytical Chemistry ,chemistry.chemical_compound ,Adsorption ,Membrane ,020401 chemical engineering ,medicine ,0204 chemical engineering ,p-Cresol ,Phase inversion (chemistry) ,0210 nano-technology ,Zeolite ,Activated carbon ,medicine.drug ,Nuclear chemistry - Abstract
In this study, porous polyethersulfone mixed-matrix membranes incorporating the adsorbents activated carbon (AC), zeolite ZSM-5, and graphene oxide (GO) were prepared via non-solvent-induced phase inversion. Such types of membranes were designed for the removal of uremic toxins, making the connection between hemodialysis and hemoadsorption more smooth. The optimal conditions (for example, compositions of the polymer solution and non-solvent bath) for preparing such composite membranes were first determined and their physicochemical properties and pore structures were characterized. Under the conditions studied, batch adsorption of p-cresol and creatinine from simulated serum on the prepared membranes reached the equilibrium within 24 h. Based on the measured isotherms at 37 °C, the Langmuir adsorption capacity of p-cresol and creatinine on the AC-incorporated membrane were obtained to be 108.7 mg and 133.3 mg, respectively, per gram of the membrane. In a closed-loop dynamic experiment for the clearance of p-cresol and creatinine from binary solutions at 37 °C, the preferential ability of these membranes for p-cresol adsorption was demonstrated; for example, 80.0% and 7.4% of p-cresol (initially, 50 mg/L) and creatinine (initially, 150 mg/L) were removed with the help of AC-incorporated membrane, respectively, within 4 h (volume 0.5 L and membrane area 58.9 cm2). The viability of fibroblast NIH/3T3 cells and hemocompatibility in the presence of the prepared mixed-matrix membranes was finally examined.
- Published
- 2020
50. PEDOT-modified laser-scribed graphene films as bginder– and metallic current collector–free electrodes for large-sized supercapacitors
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Cai Wan Chang-Jian, Kuen Chan Lee, Hsueh Sheng Tseng, Jen Hsien Huang, Wei Lin Syu, Yu-Sheng Hsiao, and Er Chieh Cho
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Supercapacitor ,Materials science ,Fabrication ,Graphene ,business.industry ,General Physics and Astronomy ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,Current collector ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Capacitance ,Energy storage ,0104 chemical sciences ,Surfaces, Coatings and Films ,law.invention ,PEDOT:PSS ,law ,Electrode ,Optoelectronics ,0210 nano-technology ,business - Abstract
The rapid development of wearable electronic devices and energy storage devices has increased the demand for flexible, lightweight, and durable supercapacitors. Nevertheless, the cost-effective synthesis of suitable active materials and the facile fabrication of electrodes for energy storage systems remain a challenge for practical applications. In this study, we developed a scalable method for the fabrication of graphene-based supercapacitors, by using a CO2 infrared laser to transform polyimide (PI) films into porous graphene. Furthermore, when modified with oxidatively polymerized poly (3,4-ethylenedioxythiophene) (PEDOT), the conductivity of the graphene films was enhanced significantly. The resultant films could be fabricated directly for use in supercapacitors without employing metallic current collectors. The current collector–free supercapacitors exhibited excellent electrochemical properties, rivaling those obtained from corresponding devices featuring metallic current electrodes. An assembled device having a large working area (4 × 4 cm2) displayed reversible capacities of 115.2, 97.0, and 78.4 F/g at rates of 0.5, 2, and 6 A/g, respectively. Moreover, only slight losses in capacitance occurred after 4000 charge/discharge cycles and 2000 bending cycles, indicative of remarkable cycling life and mechanical stability.
- Published
- 2020
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