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6 results on '"Yu-Chao Guo"'

1. Elevated N-terminal pro C-type natriuretic peptide is associated with mortality in patients undergoing transcatheter aortic valve replacement

Author

Po Hu, Han Chen, Li-Han Wang, Ju-Bo Jiang, Jia-Min Li, Meng-Yao Tang, Yu-Chao Guo, Qi-Feng Zhu, Zhao-Xia Pu, Xin-Ping Lin, Stella Ng, Xian-Bao Liu, and Jian-An Wang

Subjects
Transcatheter aortic valve replacement, Mortality, Natriuretic peptides, NT-proCNP, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Unlike N-terminal pro-B-type natriuretic peptide (NT-proBNP), which have been extensively studied, little is known about the role of N-terminal pro-C-type natriuretic peptide (NT-proCNP) for predicting survival post transcatheter aortic valve replacement (TAVR). Methods A total of 309 patients were included in the analysis. Patients were grouped into quartiles (Q1–4) according to the baseline NT-proCNP value. Blood for NT-proCNP analysis was obtained prior to TAVR procedure. The primary endpoint was mortality after a median follow-up of 32 months. Multivariable Cox proportional hazards regression models analyzed prognostic factors. The predictive capability was compared between NT-proBNP and NT-proCNP using receiver operator curve (ROC) analysis. Results A total of 309 subjects with the mean age of 76.8 ± 6.3 years, among whom 58.6% were male, were included in the analysis. A total of 58 (18.8%) patients died during follow-up. Cox multivariable analyses indicated society of thoracic surgeons (STS)-score was a strong independent predictor for mortality (hazard ratio (HR) 1.08, 95% confidential interval (CI) 1.05–1.12, P

Published
2022
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2. Circulating Irisin Level as a Biomarker for Pure Aortic Stenosis and Aortic Valve Calcification

Author

Shan-shan Wang, Jia-min Li, Po Hu, Yu-chao Guo, Xian-bao Liu, Jian-an Wang, and Han Chen

Subjects
Genetics, Pharmaceutical Science, Molecular Medicine, Cardiology and Cardiovascular Medicine, Genetics (clinical)
Abstract

Irisin, a myokine mainly secreted by skeletal and cardiac muscles, is actively involved in cardiovascular diseases. However, whether irisin is associated with aortic stenosis remains unknown. Two hundred ninety-three severe AS patients who underwent transcatheter aortic valve implantation were enrolled and followed-up for 35 months on average. Enzyme-linked immunosorbent assay (ELISA) was applied to measure circulating irisin levels. Patients were divided into two groups based on the median plasma irisin level. We found that high plasma irisin levels were independently associated with pure aortic stenosis (PAS) after adjusting for age, body mass index, history of peripheral vascular disease, and creatinine (OR = 3.015, 95% CI 1.775–5.119, P AUC = 0.647, 95% CI 0.583–0.711, P P

Published
2022

3. Crystal structure of 2,2-dichloro-1-(4-chloro-1H-indol-1-yl)ethan-1-one, C10H6Cl3NO

Author

Zhao-Yu Ma, Wan Lu, Yu-Chao Guo, and Ying-Jiao Li

Subjects
Inorganic Chemistry, General Materials Science, Condensed Matter Physics
Abstract

C10H6Cl3NO, monoclinic, P21/n (no. 14), a = 9.7097(10) Å, b = 10.6037(11) Å, c = 10.1735(10) Å, β = 96.580(4)°, V = 1040.55(18) Å3, Z = 4, R gt (F) = 0.0214, wR ref (F 2) = 0.0574, T = 101 K.

Published
2022

5. Mechanics Analysis and Finite Element Solution on Tapper Assembly of Automobile’s Drive Axle

Author

Yuan Yuan Li, Meng Wang, and Yu Chao Guo

Subjects
Stress field, Axle, Engineering, Reducer, business.industry, Displacement field, Contact analysis, Torque, General Medicine, Structural engineering, business, Size effect on structural strength, Finite element method
Abstract

Mechanical research on structural strength is done for the driving taper assembly of automobile in this paper, of which the assembly process is also explained. Based on theoretical analyses of the connection between tighten torque and axle force, the analytical model of the main reducer is established. In order to get the stress field and displacement field of the main reducer after assembly, which is used to conduct strength check, finite element analysis method is introduced. Based on these results, some theoretic suggestions for design and manufacture of the main reducer are provided.

Published
2014

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