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Your search keyword '"Yu, Yuncui"' showing total 27 results
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27 results on '"Yu, Yuncui"'

8. A multi‑omics study of diagnostic markers and the unique inflammatory tumor micro‑environment involved in tuberous sclerosis complex‑related renal angiomyolipoma

Author

Wang, Zhan, primary, Liu, Xiaoyan, additional, Wang, Wenda, additional, Wei, Jing, additional, Seery, Samuel, additional, Xu, Jiyu, additional, Sun, Haidan, additional, Yu, Yuncui, additional, Zhao, Yang, additional, Wang, Xu, additional, Liao, Zhangcheng, additional, Li, Yanan, additional, Sun, Wei, additional, Jia, Lulu, additional, and Zhang, Yushi, additional

Published
2022
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14. Accuracy of equations for predicting 24-h urinary potassium excretion from spot urine samples in Chinese children.

Author

Nie, Xiaolu, Peng, Yaguang, Cai, Siyu, Wu, Zehao, Zhang, Ying, Li, Kun, Yu, Yuncui, and Peng, Xiaoxia

Subjects
BLOOD pressure, RESEARCH methodology, POTASSIUM, DESCRIPTIVE statistics, URINALYSIS, DATA analysis software, CREATININE, CHILDREN
Abstract

The article reports that Accurate assessments of potassium intake in children are important for the early prevention of CVD. Currently, there is no simple approach for accurate estimation of potassium intake in children. We aim to evaluate the accuracy of 24-h urinary potassium excretion (24UKV) estimation in children using three common equations: the Kawasaki, Tanaka and Mage formulas, in a hospital-based setting.

Published
2022
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19. Trough concentration of itraconazole and its relationship with efficacy and safety: a systematic review and meta-analysis

Author

Zhang,Jingru, Liu,Yiwei, Nie,Xiaolu, Yu,Yuncui, Gu,Jian, Zhao,Libo, Zhang,Jingru, Liu,Yiwei, Nie,Xiaolu, Yu,Yuncui, Gu,Jian, and Zhao,Libo

Abstract

Jingru Zhang,1,2 Yiwei Liu,1 Xiaolu Nie,1 Yuncui Yu,1 Jian Gu,3 Libo Zhao1 1Clinical Research Center, Beijing Children’s Hospital, Capital Medical University, Beijing, China; 2Department of Pharmacy Administration and Clinical Pharmacy, Peking University School of Pharmaceutical Sciences, Beijing, China; 3Department of Pharmacy, Peking University People’s Hospital, Beijing, China Objectives: The optimum trough concentration of itraconazole for clinical response and safty is controversial. The objective of this systematic review and meta-analysis was to determine the optimum trough concentration of itraconazole and evaluate its relationship with efficacy and safety.Methods: We searched PubMed, EMBASE, Web of Science, the Cochrane Library, ClinicalTrials.gov, and three Chinese literature databases (CNKI, WanFang, and CBM). We included observational studies that compared clinical outcomes below or above the trough concentration cut-off value which we set as 0.25, 0.5, and 1.0 mg/L. The efficacy outcomes were rate of successful treatment, rate of prophylaxis failure and invasive fungal infection (IFI)-related mortality. The safety outcomes included incidents of hepatotoxicity and other adverse events.Results: The study included a total of 29 studies involving 2,346 patients. Our meta-analysis showed that compared with itraconazole trough concentrations (Ctrough) of ≥0.25 mg/L, levels of <0.25 mg/L significantly increased the incidence of IFI for prophylaxis (RR =3.279, 95% confidence interval [CI] 1.73–6.206). Moreover, the success rate of treatment decreased significantly at a cut-off level of 0.5 mg/L (RR =0.396, 95% CI 0.176–0.889). An itraconazole trough level of 1.0 mg/L was associated with hepatotoxicity and other adverse events in a review of many studies.Conclusion: An itraconazole trough concentration of 0.25 mg/L should be considered as the lower threshold for prophylaxis, and a target concentratio

Published
2018

20. Method Development for Clinical Comprehensive Evaluation of Pediatric Drugs Based on Multi-Criteria Decision Analysis: Application to Inhaled Corticosteroids for Children with Asthma

Author

Yu, Yuncui, primary, Jia, Lulu, additional, Meng, Yao, additional, Hu, Lihua, additional, Liu, Yiwei, additional, Nie, Xiaolu, additional, Zhang, Meng, additional, Zhang, Xuan, additional, Han, Sheng, additional, Peng, Xiaoxia, additional, and Wang, Xiaoling, additional

Published
2017
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23. Erratum to: Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population

Author

Yu, Yuncui, primary, Wang, Jing, additional, Kang, Ruiying, additional, Dong, Jing, additional, Zhang, Yuxiang, additional, Liu, Fen, additional, Yan, Yuxiang, additional, Zhu, Rong, additional, Xia, Lili, additional, Peng, Xiaoxia, additional, Zhang, Ling, additional, He, Dian, additional, Gaisano, Herbert Y., additional, Chen, Zhenwen, additional, and He, Yan, additional

Published
2015
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24. Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population

Author

Yu, Yuncui, primary, Wang, Jing, additional, Kang, Ruiying, additional, Dong, Jing, additional, Zhang, Yuxiang, additional, Liu, Fen, additional, Yan, Yuxiang, additional, Zhu, Rong, additional, Xia, Lili, additional, Peng, Xiaoxia, additional, Zhang, Ling, additional, He, Dian, additional, Gaisano, Herbert Y., additional, Chen, Zhenwen, additional, and He, Yan, additional

Published
2015
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25. One-dose vaccination associated with attenuated disease severity of adolescent and adult varicella cases in Beijing’s Fengtai District

Author

Zhang, Xue, primary, yu, yuncui, additional, Zhang, Jie, additional, P Kwan, Edwin, additional, Huang, Shengtian, additional, Wang, Zhongzhan, additional, Zhang, Jianjun, additional, Peng, Xiaoxia, additional, Yan, Yuxiang, additional, Zhang, Lin, additional, Luo, Yanxia, additional, Han, Shujing, additional, Han, Xu, additional, Liu, Guangxue, additional, Liu, Fen, additional, Zhao, Jianzhong, additional, and He, Yan, additional

Published
2014
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26. Association between HLA-B15:02and oxcarbazepine-induced cutaneous adverse reaction: a meta-analysis

Author

Liu, Yiwei, Yu, Yuncui, Nie, Xiaolu, Zhao, Libo, and Wang, Xiaoling

Abstract

Aim:HLA-B15:02has been demonstrated as a key risk factor for carbamazepine-induced severe cutaneous adverse reaction (sCAR), especially in Asian population. Oxcarbazepine (OXC) is a drug that has a similar structure of carbamazepine. However, the relationship between HLA-B15:02and induced cutaneous adverse reaction (cADR) remains unknown. This study aims to analyze this association in the published literature. Method:After filtering studies, eight studies were finally included for meta-analysis, including 32 sCAR cases, 112 mild cutaneous adverse reaction (mcADR) cases, 281 OXC tolerant control and 946 population control cases. Result:In the tolerant control group, an association was found between HLA-B15:02genotype and OXC-induced sCAR (odds ratio [OR]: 18.13; 95 CI: 6.77–48.56), but not in mcADR (OR: 1.43; 95 CI: 0.56–3.64). In population control group, an association was found between HLA-B15:02genotype and OXC-induced sCAR, (OR: 8.22; 95 CI: 3.03–22.34), but not in mcADR (OR: 2.06; 95 CI: 0.91–4.67). Discussion:Our study demonstrates that the genetic risk factor HLA-B15:02may be a factor in OXC-induced sCAR.

Published
2018
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27. Erratum to: Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population

Author

Yu, Yuncui, Wang, Jing, Kang, Ruiying, Dong, Jing, Zhang, Yuxiang, Liu, Fen, Yan, Yuxiang, Zhu, Rong, Xia, Lili, Peng, Xiaoxia, Zhang, Ling, He, Dian, Gaisano, Herbert Y., Chen, Zhenwen, and He, Yan

Subjects
Adult, Male, Metabolic Syndrome, Biochemistry, medical, Waist-Hip Ratio, Endocrinology, Diabetes and Metabolism, Cholesterol, HDL, Biochemistry (medical), Clinical Biochemistry, Cholesterol, LDL, Middle Aged, Lipid Metabolism, Polymorphism, Single Nucleotide, Cross-Sectional Studies, Logistic Models, Shab Potassium Channels, Endocrinology, Asian People, Case-Control Studies, Humans, Female, Erratum, Insulin Resistance, Biomarkers, Triglycerides
Abstract

In our previous study, we had assessed in the Chinese Han population the association of KCNB1 rs1051295 with metabolic traits indicating metabolic syndrome, and showed that KCNB1 rs1051295 genotype TT was associated with increase of waist to hip ratio (WHR), fasting insulin (FINS), triglycerides (TG) and decreased insulin sensitivity at basal condition. Here, we aimed at detecting whether there were associations between other tag SNPs of KCNB1 and favorable or unfavorable metabolic traits.We conducted a case-control design of population-based cross-sectional study to investigate the association between each of the 22 candidates tag SNPs of KCNB1 and metabolic traits in a population of 733 Chinese Han individuals. The association was assessed by multiple linear regression analysis or unconditional logistic regression analysis.We found that among the 22 selected tag SNPs, four were associated with an increase (rs3331, rs16994565) or decrease (rs237460, rs802950) in serum cholesterol levels; two of these (rs237460, rs802590) further associated or were associated with reduced serum LDL-cholesterol. Two novel tag SNPs (rs926672, rs1051295) were associated with increased serum TG levels. We also showed that KCNB1 rs926672 associated with insulin resistance by a case-control study, and two tag SNPs (rs2057077and rs4810952) of KCNB1 were associated with the measure of insulin resistance (HOMA-IR) in a cross-section study.These results indicate that KCNB1 is likely associated with metabolic traits that may either predispose or protect from progression to metabolic syndrome. This study provides initial evidence that the gene variants of KCNB1, encoding Kv2.1 channel, is associated with perturbation of lipid metabolism and insulin resistance in Chinese Han population.

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