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14 results on '"Yu, Qianfeng"'

1. A Framework Design of Children’s Educational APP Based on Metacognitive Theory

Author

Yu, Qianfeng, Wang, Jun, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Meiselwitz, Gabriele, editor, Moallem, Abbas, editor, Zaphiris, Panayiotis, editor, Ioannou, Andri, editor, Sottilare, Robert A., editor, Schwarz, Jessica, editor, and Fang, Xiaowen, editor

Published
2022
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6. Phage-Modified Clear Hydrogel for Simultaneous Detection of Multiple Bacteria

Author

Cao, Cong, Yu, Qianfeng, Yu, Zhenzhong, Tang, Keqi, and Gan, Ning

Abstract

The proliferation speed of live foodborne pathogens is fast. A small number of pathogens will have a great impact on food and the environment if positive samples are not detected timely. In this study, transparent porous hydrogel stir bars, modified by two different phages (corresponding to two different bacteria (Escherichia coliand Hafnia sp)), have been developed for rapid detection of foodborne bacteria. A large number of samples can be analyzed simultaneously with a small animal live imager device to screen out the positive samples, while an adenosine triphosphate (ATP) bioluminescence sensor can be used to quantify the number of bacteria in the positive samples. The phage has good specificity and capture ability to bacteria, which makes the method highly sensitive. In addition, the use of multiple phages also enables the method to detect multiple bacteria simultaneously. The three-dimensional structure of the hydrogel allows it to modify more phages, and its transparent nature also allows the inside bioluminescence to be detected. Both can enhance the sensitivity of the detection. Finally, the reagents needed for bioluminescence, such as d-luciferin, can also be preencapsulated in the hydrogel, thus simplifying the detection step. Under the best conditions, the detection range of the method is 102–108CFU·mL–1, and the limit of detection is 30 CFU·mL–1within 11 min. The test results of actual samples show that there is no difference between using the method developed through this study and the traditional plate counting method, but the detection time is greatly shortened.

Published
2024
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8. Heat transfer analysis of rotating tritium target of deuterium-tritium fusion neutron generator

Author

Wang Wen, Song Gang, Wang Gang, Wu Yican, and Yu Qianfeng

Subjects
Fusion neutron, Generator (computer programming), Materials science, Deuterium, Nuclear engineering, Heat transfer, General Physics and Astronomy, Tritium
Abstract

Fusion reactor is considered as one of the solutions for the sustaining development of nuclear energy. International Thermonuclear Experimental Reactor (ITER) is the biggest fusion reactor research plan in the world. High-intensity D-T fusion neutron generator can generate 14 MeV neutrons, and it matches the neutrons generated in ITER and be competently used for imitating the neutron environment in nuclear fusion reactor, which is important for the relevant experimental researches of blanket materials of fusion reactors. It can also be used for validating the correctness and reliability of the simulations and analyses in fusion basic studies, and can guide the subsequent material improvement and innovation of calculation methodology. A rotating tritium target system for D-T fusion neutron generator with a neutron yield of 1012 n·-1, i.e., a high intensity D-T fusion neutron generator, is proposed in this paper and the design, main parameters, technical difficulties and heat transfer enhancement method are introduced. The key and innovative technology of this rotating target system is the integration of the sprayed water cooling, mechanical seal and magnetic fluid seal technologies, which focuses on the heat transfer of the high heat power density in the target system. The most important technical index is that the maximum temperature on the target should not be above 200 ℃ as the tritium ions run away heavily from the tritium target when the target temperature is bigger than 200 ℃. To investigate the heat transfer characteristics of this rotating target system, the effects of water layer thickness, water flow rate and rotating speed on the heat transfer of this rotating target system are analyzed by computational fluid dynamics method. And the heat transfer processes of the target system under different heat power densities are also simulated and studied. The analysis results show that big water layer thickness, big water flow rate and high rotating speed are good for the heat transfer enhancement of the rotating target system, but the effects of the changes of the water layer thickness and water flow rate on the heat transfer process are both very small. Due to the design index, the heat power density on the target should be under a limit value, which is about 12 kW·cm-2 in the calculation results of this paper.

Published
2015

14. Effect of vascular network and nanoparticles on heat transfer and intracellular ice formation in tumor tissues during cryosurgery.

Author

Yu Q, Yi J, Zhao G, and Zhang Y

Subjects
Breast Neoplasms blood supply, Carcinoma, Ductal, Breast blood supply, Cell Line, Tumor, Computer Simulation, Female, Hot Temperature, Humans, Magnesium Oxide chemistry, Neovascularization, Pathologic, Thermodynamics, Breast Neoplasms surgery, Carcinoma, Ductal, Breast surgery, Cryosurgery methods, Ice analysis, Models, Anatomic, Nanoparticles chemistry
Abstract

Background: Cryosurgery is a physical therapy of tumor treatment which is welcome in clinics for its minimally invasive advantage. However, the high recurrence rate makes the conventional cryosurgery unsatisfactory, which needs adjuvant treatment such as introduction of nanoparticles., Objective: This study is to examine the effects of vascular network and MgO nanoparticles on heat transfer and intracellular ice formation in tumor tissues during cryosurgery., Method: We developed a multi-scale model to study the efficiency of cryosurgery, including the macro-level (mass tumor tissue) heat transfer and the micro-level (tumor cells) probability of intracellular ice formation (PIF). The model is used to examine the effects of fractal vascular network (VN) and nanoparticles with different concentration on heat transfer and PIF during cryosurgery in the breast cancer tissue (MCF-7 cells). The nucleation rate kinetic parameter and the thermodynamic parameter of MCF-7 cells are determined by nonlinear curve-fitting the published experimental data, and then the probability of intracellular ice formation of the picked points in the tumor tissue are determined using the classic model for intracellular ice nucleation with the simulated thermal profiles at those points during cryosurgery., Results and Conclusion: The introduction of nanoparticles have significantly enhanced the heat transfer in the mass tumor tissue and increased the PIF of tumor cells, indicating the nanocryosurgery is more efficient than conventional cryosurgery.

Published
2014

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