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1. Plasma Matrix Metalloproteinase-1 as a Prognostic Biomarker in Oral Cavity Squamous Cell Carcinoma

Author

Tsai TY, Kao HK, Huang Y, Chang YT, Young CK, Hung SY, Chang YS, Yu JS, and Chang KP

Subjects
oral cancer, mmp, squamous cell carcinoma, elisa, oscc, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Tsung-You Tsai,1,&ast; Huang-Kai Kao,2,3,&ast; Yenlin Huang,4 Ya-Ting Chang,5 Chi-Kuang Young,1 Shao-Yu Hung,3 Yu-Sun Chang,5 Jau-Song Yu,1,5,6 Kai-Ping Chang1,2,5 1Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan; 2College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan; 4Department of Pathology, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan; 5Molecular Medicine Research Center, Chang Gung University, Taoyuan, 33302, Taiwan; 6Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Taoyuan, 33302, Taiwan&ast;These authors contributed equally to this workCorrespondence: Kai-Ping Chang, Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, No. 5, Fu-Hsing St, Kweishan, Taoyuan, 33305, Taiwan, Tel +886-3-3281200 ext.3967, Fax +886-3-3979361, Email dr.kpchang@gmail.comPurpose: Plasma matrix metalloproteinase-1 (MMP-1) is a collagenase encoded by the MMP-1 gene. However, the prognostic value of plasma MMP-1 levels in oral cavity squamous cell carcinoma (OSCC) has yet to be elucidated. The study is the first to use a cohort of OSCC patients to assess the association of plasma MMP-1 levels with clinicopathological factors/survival outcomes in OSCC patients.Patients and Methods: A total of 677 patients were retrospectively enrolled, including 276 oral potentially malignant disease (OPMD) and 401 OSCC patients from 2013 to 2021. Pretreatment plasma MMP-1 levels were measured with an enzyme-linked immunosorbent assay, and the values were compared between OPMD and OSCC patients. Furthermore, the association of plasma MMP-1 levels and clinicopathological characteristics/survival outcomes in OSCC patients was investigated.Results: Plasma MMP-1 levels were significantly higher in OSCC patients than in OPMD patients (p = 0.04). In the OSCC group, plasma MMP-1 levels were significantly higher in females, tumor depth ≥ 10 mm, advanced pT classification and advanced overall stage (p = 0.04, < 0.001, < 0.001, 0.002, respectively). Higher plasma MMP-1 levels were significantly associated with poorer overall, disease-specific, disease-free, locoregional recurrence-free and distant metastasis-free survival (p = 0.003, 0.02, 0.005, 0.01, 0.001, respectively). Multivariate analysis revealed that plasma MMP-1 levels were a significant predictor for overall, disease-free, and distant metastasis-free survival (p = 0.03, 0.02, and 0.010, respectively).Conclusion: Plasma MMP-1 levels are associated with more severe clinicopathological manifestations and can also be regarded as a significant prognostic factor for OSCC posttreatment outcomes.Keywords: oral cancer, MMP, squamous cell carcinoma, ELISA, OSCC

Published
2022

3. Measurements of the branching fractions of the singly Cabibbo-suppressed decays D-0 -> omega eta, eta(()'())pi(0) and eta(()'())eta

Author

Ablikim, M, Achasov, MN, Ahmed, S, Albayrak, O, Albrecht, M, Ambrose, DJ, Amoroso, A, An, FF, An, Q, Bai, JZ, Bakina, O, Ferroli, RB, Ban, Y, Bennett, DW, Bennett, JV, Berger, N, Bertani, M, Bettoni, D, Bian, JM, Bianchi, F, Boger, E, Boyko, I, Briere, RA, Cai, H, Cai, X, Cakir, O, Calcaterra, A, Cao, GF, Cetin, SA, Chai, J, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, JC, Chen, ML, Chen, PL, Chen, SJ, Chen, XR, Chen, YB, Chu, XK, Cibinetto, G, Dai, HL, Dai, JP, Dbeyssi, A, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, De Mori, F, Ding, Y, Dong, C, Dong, J, Dong, LY, Dong, MY, Dou, ZL, Du, SX, Duan, PF, Fang, J, Fang, SS, Fang, X, Fang, Y, Farinelli, R, Fava, L, Fegan, S, Feldbauer, F, Felici, G, Feng, CQ, Fioravanti, E, Fritsch, M, Fu, CD, Gao, Q, Gao, XL, Gao, Y, Gao, YG, Gao, Z, Garzia, I, Goetzen, K, Gong, L, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, S, Gu, YT, Guo, AQ, Guo, LB, Guo, RP, Guo, YP, Haddadi, Z, Hafner, A, Han, S, Hao, XQ, Harris, FA, He, KL, He, XQ, Heinsius, FH, Held, T, Heng, YK, Holtmann, T, Hou, ZL, Hu, C, Hu, HM, Hu, T, Hu, Y, Huang, GS, Huang, JS, Huang, XT, Huang, XZ, Huang, ZL, Hussain, T, Andersson, WI, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, XS, Jiang, XY, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Johansson, T, Julin, A, Kalantar-Nayestanaki, N, Kang, XL, Kang, XS, Kavatsyuk, M, Ke, BC, Khan, T, Kiese, P, Kliemt, R, Kloss, B, Kolcu, OB, Kopf, B, Kornicer, M, Kupsc, A, Kuhn, W, Lange, JS, Lara, M, Larin, P, Lavezzi, L, Leithoff, H, Leng, C, Li, C, Li, DM, Li, F, Li, FY, Li, G, Li, HB, Li, HJ, Li, JC, Li, J, Li, K, Li, L, Li, PL, Li, PR, Li, QY, Li, T, Li, WD, Li, WG, Li, XL, Li, XN, Li, XQ, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Lin, DX, Liu, B, Liu, BJ, Liu, CX, Liu, D, Liu, FH, Liu, F, Liu, HB, Liu, HM, Liu, H, Liu, JB, Liu, JP, Liu, JY, Liu, K, Liu, KY, Liu, LD, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Long, YF, Lou, XC, Lu, HJ, Lu, JG, Lu, Y, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lyu, XR, Ma, FC, Ma, HL, Ma, LL, Ma, MM, Ma, QM, Ma, T, Ma, XN, Ma, XY, Ma, YM, Maas, FE, Maggiora, M, Malik, QA, Mao, YJ, Mao, ZP, Marcello, S, Messchendorp, JG, Mezzadri, G, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Mo, YJ, Morales, CM, Morello, G, Muchnoi, NY, Muramatsu, H, Musiol, P, Nefedov, Y, Nerling, F, Nikolaev, IB, Ning, Z, Nisar, S, Niu, SL, Niu, XY, Olsen, SL, Ouyang, Q, Pacetti, S, Pan, Y, Papenbrock, M, Patteri, P, Pelizaeus, M, Pellegrino, J, Peng, HP, Peters, K, Pettersson, J, Ping, JL, Ping, RG, Poling, R, Prasad, V, Qi, HR, Qi, M, Qian, S, Qiao, CF, Qin, JJ, Qin, N, Qin, XS, Qin, ZH, Qiu, JF, Rashid, KH, Redmer, CF, Ripka, M, Rong, G, Rosner, C, Sarantsev, A, Savrie, M, Schnier, C, Schoenning, K, Shan, W, Shao, M, Shen, CP, Shen, PX, Shen, XY, Sheng, HY, Song, JJ, Song, WM, Song, XY, Sosio, S, Spataro, S, Sun, GX, Sun, JF, Sun, SS, Sun, XH, Sun, YJ, Sun, YK, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Tiemens, M, Tsednee, B, Uman, I, Varner, GS, Wang, B, Wang, BL, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, WP, Wang, XF, Wang, Y, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZH, Wang, ZY, Weber, T, Wei, DH, Weidenkaff, P, Wen, SP, Wiedner, U, Wolke, M, Wu, LH, Wu, LJ, Wu, Z, Xia, L, Xia, Y, Xiao, D, Xiao, H, Xiao, YJ, Xiao, ZJ, Xie, YG, Xie, YH, Xiong, XA, Xiu, QL, Xu, GF, Xu, JJ, Xu, L, Xu, QJ, Xu, QN, Xu, XP, Yan, L, Yan, WB, Yan, WC, Yan, YH, Yang, HJ, Yang, HX, Yang, L, Yang, YH, Yang, YX, Yang, Y, Ye, M, Ye, MH, Yin, JH, You, ZY, Yu, BX, Yu, CX, Yu, JS, Yuan, CZ, Yuan, Y, Yuncu, A, Zafar, AA, Zallo, A, Zeng, Y, Zeng, Z, Zhang, BX, Zhang, BY, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, J, Zhang, JL, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, K, Zhang, L, Zhang, SQ, Zhang, XY, Zhang, YH, Zhang, YT, Zhang, Y, Zhang, ZH, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, JW, Zhao, JY, Zhao, JZ, Zhao, L, Zhao, MG, Zhao, Q, Zhao, SJ, Zhao, TC, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, WJ, Zheng, YH, Zhong, B, Zhou, L, Zhou, X, Zhou, XK, Zhou, XR, Zhou, XY, Zhou, YX, Zhu, J, Zhu, K, Zhu, KJ, Zhu, S, Zhu, SH, Zhu, XL, Zhu, YC, Zhu, YS, Zhu, ZA, Zhuang, J, Zotti, L, Zou, BS, and Zou, JH

Published
2018

5. Synthesis and Luminescent Properties of Eu3+ Activated SrWO4 Nanocrystalline Microspheres

Author

Yu Js and Bharat Lk

Subjects
Materials science, Photoluminescence, Biomedical Engineering, Analytical chemistry, Bioengineering, Phosphor, General Chemistry, Condensed Matter Physics, Nanocrystalline material, General Materials Science, Crystallite, Emission spectrum, Electric dipole transition, Luminescence, Visible spectrum
Abstract

We synthesized the Eu3+ activated SrWO4 nanocrystalline microspheres by a simple and facile synthesis route. X-ray diffraction patterns exhibited a unique phase of SrWO4:Eu3+ scheelite structure with an average crystallite size of 58.9 nm. Fourier transform infrared spectra revealed the presence of absorption bands of WO4(2-) and polyethylene glycol. The optical properties were investigated by varying the Eu3+ ion concentration. Photoluminescence (PL) excitation spectra confirmed that these phosphors are able to be excited by UV, near UV, and visible wavelengths. PL emission spectra showed the bright-red emission due to the 5D0 --> 7F2 electric dipole transition from the sites of non-inversion symmetry. The optimal doping concentration of Eu3+ ions was found to be 7 mol%. Blending this phosphor with YAG:Ce3+ phosphors may compensate their lack of a red spectral component, which leads to a good natural white light for indoor illumination.

Published
2013

7. Measurement of the absolute branching fraction of D-vertical bar -> (K)over-bar(0)e(vertical bar) nu(e) via (K)over-bar(0) -> pi(0)pi(0)

Author

Ablikim, M, Achasov, N, Ai, XC, Albayrak, O, Albrecht, M, Ambrose, DJ, Amoroso, A, An, FF, An, Q, Bai, JZ, Ferroli, RB, Ban, Y, Bennett, DW, Bennett, JV, Bertani, M, Bettonin, D, Bian, JM, Bianchi, F, Boger, E, Boyko, I, Briere, RA, Cai, H, Cai, X, Cakir, O, Caleaterra, A, Cao, GF, Cetin, SA, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, HY, Chen, JC, Chen, ML, Chen, S, Chen, SJ, Chen, X, Chen, XR, Chen, YB, Cheng, HP, Chu, XK, Cibinetto, G, Dai, HL, Dai, JP, Dbeyssi, A, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, De Mori, F, Ding, Y, Dong, C, Dong, J, Dong, LY, Dong, MY, Dou, ZL, Du, SX, Duan, PF, Fan, JZ, Fang, J, Fang, SS, Fang, X, Fang, Y, Farinelli, R, Fava, L, Fedorov, O, Feldbauer, F, Felici, G, Feng, CQ, Fioravanti, E, Fritsch, M, Fu, CD, Gao, Q, Gao, XL, Gao, XY, Gao, Y, Gao, Z, Garzia, I, Goetzen, K, Gong, L, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, YT, Guan, YH, Guo, AQ, Guo, LB, Guo, RP, Guo, Y, Guo, YP, Haddadi, Z, Hafner, A, Han, S, Hao, XQ, Harris, FA, He, KL, Held, T, Heng, YK, Hou, ZL, Hu, C, Hu, HM, Hu, JF, Hu, T, Hu, Y, Huang, GS, Huang, JS, Huang, XT, Huang, XZ, Huang, Y, Huang, ZL, Hussain, T, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, LW, Jiang, XS, Jiang, XY, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Johansson, T, Julin, A, Kalantar-Nayestanaki, N, Kang, XL, Kang, XS, Kavatsyuk, M, Ke, BC, Kiese, P, Kliemt, R, Kloss, B, Kolc, OB, Kopf, B, Kornicer, M, Kupse, A, Kuehn, W, Lange, JS, Lara, M, Larin, P, Leng, C, Li, C, Li, DM, Li, F, Li, FY, Li, G, Li, HB, Li, HJ, Li, JC, Li, J, Li, K, Li, L, Li, PR, Li, QY, Li, T, Li, WD, Li, WG, Li, XL, Li, XN, Li, XQ, Li, YB, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Lin, DX, Liu, B, Liu, BJ, Liu, CX, Liu, D, Liu, FH, Liu, F, Liu, HB, Liu, HH, Liu, HM, Liu, J, Liu, JB, Liu, JP, Liu, JY, Liu, K, Liu, KY, Liu, LD, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Lou, XC, Lu, HJ, Lu, JG, Lu, Y, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lu, XR, Ma, FC, Ma, HL, Ma, LL, Ma, MM, Ma, QM, Ma, T, Ma, XN, Ma, XY, Ma, YM, Maas, FE, Maggiora, M, Mao, YJ, Mao, ZP, Marcello, S, Messchendorp, JG, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Mo, YJ, Morales, CM, Muchnoi, NY, Muramatsu, H, Nefedov, Y, Nerling, F, Nikolaev, IB, Ning, Z, Nisar, S, Niu, SL, Niu, XY, Olsen, SL, Ouyang, Q, Pacetti, S, Pan, Y, Patteri, P, Pelizaeus, M, Peng, HP, Peters, K, Pettersson, J, Ping, JL, Ping, RG, Poling, R, Prasad, V, Qi, HR, Qi, M, Qian, S, Qiao, CF, Qin, LQ, Qin, N, Qin, XS, Qin, ZH, Qiu, JF, Rashid, KH, Redmer, CF, Ripka, M, Rong, G, Rosner, C, Ruan, XD, Sarantsev, A, Savrie, M, Schoenning, K, Schumann, S, Shan, W, Shao, M, Shen, CP, Shen, PX, Shen, XY, Sheng, HY, Shi, M, Song, WM, Song, XY, Sosio, S, Spataro, S, Sun, GX, Sun, JF, Sun, SS, Sun, XH, Sun, YJ, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Tiemens, M, Ullrich, M, Uman, I, Varner, GS, Wang, B, Wang, BL, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, W, Wang, WP, Wang, XF, Wang, Y, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZH, Wang, ZY, Weber, T, Wei, DH, Weidenkaff, P, Wen, SP, Wiedner, U, Wolke, M, Wu, LH, Wu, LJ, Wu, Z, Xia, L, Xia, Y, Xiao, D, Xiao, H, Xiao, ZJ, Xie, YG, Xiu, QL, Xu, GF, Xu, JJ, Xu, L, Xu, QJ, Xu, QN, Xu, XP, Yan, L, Yan, WB, Yan, WC, Yan, YH, Yang, HJ, Yang, HX, Yang, L, Yang, YX, Ye, M, Ye, MH, Yin, JH, Yu, BX, Yu, CX, Yu, JS, Yuan, CZ, Yuan, WL, Yuan, Y, Yuncu, A, Zafar, AA, Zallo, A, Zeng, Y, Zeng, Z, Zhang, BX, Zhang, BY, Zhang, C, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, J, Zhang, JJ, Zhang, JL, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, K, Zhang, L, Zhang, SQ, Zhang, XY, Zhang, Y, Zhang, YH, Zhang, YN, Zhang, YT, Zhang, ZH, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, JW, Zhao, JY, Zhao, JZ, Zhao, L, Zhao, MG, Zhao, Q, Zhao, QW, Zhao, SJ, Zhao, TC, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, WJ, Zheng, YH, Zhong, B, Zhou, L, Zhou, X, Zhou, XK, Zhou, XR, Zhou, XY, Zhu, K, Zhu, KJ, Zhu, S, Zhu, SH, Zhu, XL, Zhu, YC, Zhu, YS, Zhu, ZA, Zhuangig, J, Zotti, L, Zou, BS, Zou, JH, Collaboration, BESIII, Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü., Tapan, İlhan, İstanbul Arel Üniversitesi, and [Ablikim, M. -- Ai, X. 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B. -- Zheng, J. P. -- Zhou, L. -- Zhou, X. Y. -- Zhu, K. -- Zhu, K. J. -- Zhu, S. -- Zhu, Y. S. -- Zhu, Z. A. -- Zhuangig, J. -- Zou, B. S. -- Zou, J. H.] Inst High Energy Phys, Beijing 100049, Peoples R China -- [Chen, H. Y. -- Gao, X. Y. -- Li, Y. B. -- Qi, H. R. -- Shen, C. P.] Beihang Univ, Beijing 100191, Peoples R China -- [Li, Lei] Beijing Inst Petrochem Technol, Beijing 102617, Peoples R China -- [Albrecht, M. -- Chen, S. -- Held, T. -- Huang, G. S. -- Kopf, B. -- Pelizaeus, M. -- Wiedner, U.] Ruhr Univ Bochum, D-44780 Bochum, Germany -- [Albayrak, O. -- Bennett, J. V. -- Briere, R. A. -- Ke, B. C.] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA -- [Liu, Feng -- Mo, Y. J. -- Zhang, Z. H.] Cent China Normal Univ, Wuhan 430079, Peoples R China -- [Ye, M. H.] China Ctr Adv Sci & Technol, Beijing 100190, Peoples R China -- [Nisar, S.] COMSATS Inst Informat Technol, Def Rd,Raiwind Rd, Lahore 54000, Pakistan -- [Achasov, N. -- Muchnoi, N. Yu. -- Nikolaev, I. B.] GI Budker Inst Nucl Phys SB RAS BINP, Novosibirsk 630090, Russia -- [Goetzen, K. -- Peters, K.] GSI Helmholtzctr Heavy Ion Res GmbH, D-64291 Darmstadt, Germany -- [Liao, G. R. -- Wei, D. H. -- Yang, Y. X.] Guangxi Normal Univ, Guilin 541004, Peoples R China -- [Gu, Y. T. -- Liu, H. B. -- Ruan, X. D.] Guangxi Univ, Nanning 530004, Peoples R China -- [Li, K. -- Xu, Q. N.] Hangzhou Normal Univ, Hangzhou 310036, Zhejiang, Peoples R China -- [Dbeyssi, A. -- Fritsch, M. -- Kliemt, R. -- Larin, P. -- Lin, D. X. -- Maas, F. E. -- Morales, C. Morales -- Nerling, F. -- Rosner, Ch. -- Wang, Y. D.] Helmholtz Inst Mainz, Johann Joachim Becher Weg 45, D-55099 Mainz, Germany -- [Hao, X. Q. -- Huang, J. S. -- Sun, J. F.] Henan Normal Univ, Xinxiang 453007, Peoples R China -- [Lara, M. -- Liu, H. H.] Henan Univ Sci & Technol, Luoyang 471003, Peoples R China -- [Cheng, H. P. -- Jiao, Z. -- Lu, H. 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Subjects
Semileptonic decays, E(+)E(-), Physics, semileptonic decays, Monte-carlo, Physics, particles & fields, Absolute branching fraction, Physics, nuclear, Charmed mesons, CP Violation, Deterioration, CKM Matrix, charmed mesons, BESIII/BEPCII, absolute branching fraction
Abstract

WOS: 000389144400002, By analyzing 2.93 fb(-1) data collected at the center-of-mass energy root s = 3.773 GeV with the BESIII detector, we measure the absolute branching fraction of the semileptonic decay D+ -> (K) over bar (0)e(+)nu(e) to be B(D (+) -> (K) over bar (0)e(+)nu(e)) = (8.59 +/- 0.14 +/- 0.21)% using (K) over bar (0) -> K-S(0) -> pi(0) pi(0), where the first uncertainty is statistical and the second systematic. Our result is consistent with previous measurements within uncertainties.., National Key Basic Research Program of China [2009CB825204, 2015CB856700]; National Natural Science Foundation of China (NSFC) [10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524, 11475123, 11405046, U1332103]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS Center for Excellence in Particle Physics (CCEPP); Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of NSFC [11179007, U1232201, U1332201, U1532101]; Joint Large-Scale Scientific Facility Funds of CAS [KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; National 1000 Talents Program of China; IN-PAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG (Collaborative Research Center) [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) [530-4CDP03]; Ministry of Development of Turkey [DPT2006K-120470]; National Natural Science Foundation of China (NSFC); Russian Foundation for Basic Research [14-07-91152]; Swedish Resarch Council; U. S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-SC0012069, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], Supported by National Key Basic Research Program of China (2009CB825204, 2015CB856700), National Natural Science Foundation of China (NSFC) (10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524, 11475123), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, CAS Center for Excellence in Particle Physics (CCEPP), Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of NSFC and CAS (11179007, U1232201, U1332201, U1532101), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, National 1000 Talents Program of China, IN-PAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy, Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Natural Science Foundation of China (NSFC) (11405046, U1332103), Russian Foundation for Basic Research (14-07-91152), Swedish Resarch Council, U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-SC0012069, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0).

Published
2016

8. The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development

Author

Adams, CJ, Yu, JS, Mao, JH, Jen, KY, Costes, SV, Wade, M, Shoemake, J, Aina, OH, Del Rosario, R, Menchavez, PT, Cardiff, RD, Wahl, GM, and Balmain, A

Subjects
Male, cancer radiation, Neoplasms, Radiation-Induced, Proline, Carcinogenesis, Trp53, Oncology and Carcinogenesis, Inbred C57BL, Article, Genomic Instability, Polyploidy, Mice, Neoplasms, Genetics, Autophagy, 2.1 Biological and endogenous factors, Animals, Amino Acid Sequence, Oncology & Carcinogenesis, Cancer, Sequence Deletion, Hematology, genomic instability, Mice, Inbred C57BL, Radiation-Induced, Gamma Rays, Female, Tumor Suppressor Protein p53
Abstract

© 2015 Wiley Periodicals, Inc. The tumor suppressor TP53 can initiate a plethora of anti-proliferative effects to maintain genomic integrity under conditions of genotoxic stress. The N-terminal proline-rich domain (PRD) of TP53 is important in the regulation of TP53 activity and stability. A common polymorphism at codon 72 in this region has been associated with altered cancer risk in humans. The Trp53ΔP mouse, which carries a germline homozygous deletion of a region of the PRD, does not develop spontaneous tumors in a mixed 129/Sv and C57BL/6 genetic background, but is highly susceptible to a broad range of tumor types following total body exposure to 4 Gy gamma (γ) radiation. This contrasts with the tumor spectrum in Trp53 null (−/−) mice, which mainly develop thymic lymphomas and osteosarcomas. Analysis of genomic instability in tissues and cells from Trp53ΔP mice demonstrated elevated basal levels of aneuploidy, but this is not sufficient to drive spontaneous tumorigenesis, which requires an additional DNA damage stimulus. Levels of genomic instability did not increase significantly in Trp53ΔP mice following irradiation exposure, suggesting that other radiation effects including tissue inflammation, altered metabolism or autophagy, may play an important role. The Trp53ΔP mouse is a novel model to dissect the mechanisms of tumor development induced by radiation exposure. © 2015 Wiley Periodicals, Inc.

Published
2016

9. Measurement of the branching fraction for psi(3770) -> gamma chi c0

Author

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Abstract

WOS: 000368783600015, By analyzing a data set of 2.92 fb(-1) of e(+) e(-) collision data taken at root s = 3.773 GeVand 106.41 x 10(6) psi(3686) decays taken at root s = 3.686 GeVwith the BESIII detector at the BEPCII collider, we measure the branching fraction and the partial decay width for psi(3770)->gamma chi c0 to be B(psi(3770)->gamma chi c0) = (6.88 +/- 0.28 +/- 0.67) x 10(-3) and Gamma[psi(3770)->gamma chi c0] = (187 +/- 8 +/- 19) keV, respectively. These are the most precise measurements to date. (C) 2015 The Authors. Published by Elsevier B.V., National Key Basic Research Program of China [2009CB825204, 2015CB856700]; National Natural Science Foundation of China (NSFC) [10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; NSFC [11179007, U1232201, U1332201]; CAS [11179007, U1232201, U1332201, KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; CAS Center for Excellence in Particle Physics (CCEPP); INPAC; Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center [CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. This work is supported in part by the National Key Basic Research Program of China under Contract Nos. 2009CB825204 and 2015CB856700; National Natural Science Foundation of China (NSFC) under Contracts Nos. 10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contracts Nos. 11179007, U1232201, U1332201; CAS under Contracts Nos. KJCX2-YW-N29, KJCX2-YW-N45; 100 Talents Program of CAS; the CAS Center for Excellence in Particle Physics (CCEPP); INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Collaborative Research Center Contract No. CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; U.S. Department of Energy under Contracts Nos. DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2016

10. Measurement of the e(+)e(-) -> pi(+) pi(-) cross section between 600 and 900 MeV using initial state radiation

Author

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Subjects
Nuclear and High Energy Physics, Particle physics, BESIII, детектор, Hadron, KLOE DETECTOR, BESIII, Hadronic cross section, Initial state radiation, Muon anomaly, Pion form factor, 7. Clean energy, 01 natural sciences, NO, law.invention, Subatomär fysik, Pion, law, CMD-2, 0103 physical sciences, Subatomic Physics, Physics, nuclear, Vacuum polarization, 010306 general physics, Collider, Physics, ELECTRON-POSITRON ANNIHILATION, HADRONIC CONTRIBUTIONS, Luminosity (scattering theory), FLAVOR FACTORIES, 010308 nuclear & particles physics, SIGMA(E(+)E(-), Form factor (quantum field theory), G-2, Order (ring theory), Mesons, Detector, Lattice QCD, lcsh:QC1-999, BEPCII, коллайдер, Astronomy & astrophysics, Physics, particles & fields, PI(+)PI(-)), Energy (signal processing), lcsh:Physics
Abstract

WOS: 000368783600087, We extract the e(+) e(-) -> pi(+) pi(-) cross section in the energy range between 600 and 900 MeV, exploiting the method of initial state radiation. A data set with an integrated luminosity of 2.93 fb(-1) taken at a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider is used. The cross section is measured with a systematic uncertainty of 0.9%. We extract the pion form factor vertical bar F pi vertical bar(2) as well as the contribution of the measured cross section to the leading-order hadronic vacuum polarization contribution to (g - 2)(mu). We find this value to be a(mu)(pi pi,LO) (600-900 MeV) = (368.2 +/- 2.5(stat)+/- 3.3(sys)).10(-10), which is between the corresponding values using the BaBar or KLOE data. (C) 2015 The Authors. Published by Elsevier B.V., National Key Basic Research Program of China [2015CB856700]; National Natural Science Foundation of China (NSFC) [11125525, 11235011, 11322544, 11335008, 11425524]; Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; CAS Center for Excellence in Particle Physics (CCEPP); Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of the NSFC; CAS [11179007, U1232201, U1332201, KJCX2-YW-N29, KJCX2-YW-N45]; 100 Talents Program of CAS; National 1000 Talents Program of China; INPAC; Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG [Collaborative Research Center CRC-1044]; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey [DPT2006K-120470]; Russian Foundation for Basic Research [14-07-91152]; Swedish Resarch Council; U.S. Department of Energy [DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118]; U.S. National Science Foundation; University of Groningen (RuG); Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea [R32-2008-000-10155-0], The BESIII Collaboration thanks the staff of BEPCII and the IHEP computing center for their strong support. We thank Thomas Teubner for the recalculation of amupi pi,LO (600-900 MeV) and Fedor Ignatov for the useful discussions. This work is supported in part by National Key Basic Research Program of China under Contract No. 2015CB856700; National Natural Science Foundation of China (NSFC) under Contract Nos. 11125525, 11235011, 11322544, 11335008, 11425524; the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; the CAS Center for Excellence in Particle Physics (CCEPP); the Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contract Nos. 11179007, U1232201, U1332201; CAS under Contract Nos. KJCX2-YW-N29, KJCX2-YW-N45; 100 Talents Program of CAS; National 1000 Talents Program of China; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG under Contract No. Collaborative Research Center CRC-1044; Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey under Contract No. DPT2006K-120470; Russian Foundation for Basic Research under Contract No. 14-07-91152; The Swedish Resarch Council; U.S. Department of Energy under Contract Nos. DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118; U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fur Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea under Contract No. R32-2008-000-10155-0.

Published
2016

11. Measurement of the branching fractions of D-s(+) -> eta ' X and D-s(+) -> eta 'rho(+) in e(+)e(-) -> Ds+Ds

Author

Ablikim, M, Achasov, MN, Ai, XC, Albayrak, O, Albrecht, M, Ambrose, DJ, Amoroso, A, An, FF, An, Q, Bai, JZ, Ferroli, RB, Ban, Y, Bennett, DW, Bennett, JV, Bertani, M, Bettoni, D, Bian, JM, Bianchi, F, Boger, E, Boyko, I, Briere, RA, Cai, H, Cai, X, Cakir, O, Calcaterra, A, Cao, GF, Cetin, SA, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, HY, Chen, JC, Chen, ML, Chen, SJ, Chen, X, Chen, XR, Chen, YB, Cheng, HP, Chu, XK, Cibinetto, G, Dai, HL, Dai, JP, Dbeyssi, A, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, De Mori, F, Ding, Y, Dong, C, Dong, J, Dong, LY, Dong, MY, Du, SX, Duan, PF, Eren, EE, Fan, JZ, Fang, J, Fang, SS, Fang, X, Fang, Y, Fava, L, Feldbauer, F, Felici, G, Feng, CQ, Fioravanti, E, Fritsch, M, Fu, CD, Gao, Q, Gao, XY, Gao, Y, Gao, Z, Garzia, I, Geng, C, Goetzen, K, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, YT, Guan, YH, Guo, AQ, Guo, LB, Guo, Y, Guo, YP, Haddadi, Z, Hafner, A, Han, S, Han, YL, Hao, XQ, Harris, FA, He, KL, He, ZY, Held, T, Heng, YK, Hou, ZL, Hu, C, Hu, HM, Hu, JF, Hu, T, Hu, Y, Huang, GM, Huang, GS, Huang, HP, Huang, JS, Huang, XT, Huang, Y, Hussain, T, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, LL, Jiang, LW, Jiang, XS, Jiang, XY, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Johansson, T, Julin, A, Kalantar-Nayestanaki, N, Kang, XL, Kang, XS, Kavatsyuk, M, Ke, BC, Kiese, P, Kliemt, R, Kloss, B, Kolcu, OB, Kopf, B, Kornicer, M, Kuehn, W, Kupsc, A, Lange, JS, Lara, M, Larin, P, Leng, C, Li, C, Li, CH, Li, DM, Li, F, Li, G, Li, HB, Li, JC, Li, J, Li, K, Li, L, Li, PR, Li, T, Li, WD, Li, WG, Li, XL, Li, XM, Li, XN, Li, XQ, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Lin, DX, Liu, BJ, Liu, CX, Liu, FH, Liu, F, Liu, HB, Liu, HH, Liu, HM, Liu, J, Liu, JB, Liu, JP, Liu, JY, Liu, K, Liu, KY, Liu, LD, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, XX, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Lou, XC, Lu, HJ, Lu, JG, Lu, RQ, Lu, Y, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lv, M, Lyu, XR, Ma, FC, Ma, HL, Ma, LL, Ma, QM, Ma, T, Ma, XN, Ma, XY, Maas, FE, Maggiora, M, Mao, YJ, Mao, ZP, Marcello, S, Messchendorp, JG, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Mo, YJ, Morales, CM, Moriya, K, Muchnoi, NY, Muramatsuau, H, Nefedov, Y, Nerling, F, Nikolaev, IB, Ning, Z, Nisar, S, Niu, SL, Niu, XY, Olsen, SL, Ouyang, Q, Pacetti, S, Patteri, P, Pelizaeus, M, Peng, HP, Peters, K, Pettersson, J, Ping, JL, Ping, RG, Poling, R, Prasad, V, Pu, YN, Qi, M, Qian, S, Qiao, CF, Qin, LQ, Qin, N, Qin, XS, Qin, Y, Qin, ZH, Qiu, JF, Rashid, KH, Redmer, CF, Ren, HL, Ripka, M, Rong, G, Rosner, C, Ruan, XD, Santoro, V, Sarantsev, A, Savrie, M, Schoenning, K, Schumann, S, Shan, W, Shao, M, Shen, CP, Shen, PX, Shen, XY, Sheng, HY, Song, WM, Song, XY, Sosio, S, Spataro, S, Sun, GX, Sun, JF, Sun, SS, Sun, YJ, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Tiemens, M, Ullrich, M, Uman, I, Varner, GS, Wang, B, Wang, BL, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, SG, Wang, W, Wang, XF, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZH, Wang, ZY, Weber, T, Wei, DH, Wei, JB, Weidenkaff, P, Wen, SP, Wiedner, U, Wolke, M, Wu, LH, Wu, Z, Xia, LG, Xia, Y, Xiao, D, Xiao, ZJ, Xie, YG, Xiu, QL, Xu, GF, Xu, L, Xu, QJ, Xu, QN, Xu, XP, Yan, L, Yan, WB, Yan, WC, Yan, YH, Yang, HJ, Yang, HX, Yang, L, Yang, Y, Yang, YX, Ye, H, Ye, M, Ye, MH, Yin, JH, Yu, BX, Yu, CX, Yu, HW, Yu, JS, Yuan, CZ, Yuan, WL, Yuan, Y, Yuncu, A, Zafar, AA, Zallo, A, Zeng, Y, Zhang, BX, Zhang, BY, Zhang, C, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, JJ, Zhang, JL, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, K, Zhang, L, Zhang, SH, Zhang, XY, Zhang, Y, Zhang, YN, Zhang, YH, Zhang, YT, Zhang, ZH, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, JW, Zhao, JY, Zhao, JZ, Zhao, L, Zhao, MG, Zhao, Q, Zhao, QW, Zhao, SJ, Zhao, TC, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, WJ, Zheng, YH, Zhong, B, Zhou, L, Zhou, X, Zhou, XK, Zhou, XR, Zhou, XY, Zhu, K, Zhu, KJ, Zhu, S, Zhu, XL, Zhu, YC, Zhu, YS, Zhu, ZA, Zhuang, J, Zotti, L, Zou, BS, Zou, JH, and Collaboration, BESIII

Subjects
D-s, BESIII, Branching fractions
Published
2015

22. Study of psi(3686) -> pi(0)h(c), h(c) -> gamma eta(c) via eta(c) exclusive decays

Author

Ablikim, M, Achasov, MN, Albayrak, O, Ambrose, DJ, An, FF, An, Q, Bai, JZ, Ban, Y, Becker, J, Bennett, JV, Bertani, M, Bian, JM, Boger, E, Bondarenko, O, Boyko, I, Briere, RA, Bytev, V, Cai, X, Cakir, O, Calcaterra, A, Cao, GF, Cetin, SA, Chang, JF, Chelkov, G, Chen, G, Chen, HS, Chen, JC, Chen, ML, Chen, SJ, Chen, X, Chen, YB, Cheng, HP, Chu, YP, Cronin-Hennessy, D, Dai, HL, Dai, JP, Dedovich, D, Deng, ZY, Denig, A, Denysenko, I, Destefanis, M, Ding, WM, Ding, Y, Dong, LY, Dong, MY, Du, SX, Fang, J, Fang, SS, Fava, L, Feldbauer, F, Feng, CQ, Ferroli, RB, Fu, CD, Fu, JL, Gao, Y, Geng, C, Goetzen, K, Gong, WX, Gradl, W, Greco, M, Gu, MH, Gu, YT, Guan, YH, Guo, AQ, Guo, LB, Guo, YP, Han, YL, Harris, FA, He, KL, He, M, He, ZY, Held, T, Heng, YK, Hou, ZL, Hu, HM, Hu, T, Huang, GM, Huang, GS, Huang, JS, Huang, XT, Huang, YP, Hussain, T, Ji, CS, Ji, Q, Ji, QP, Ji, XB, Ji, XL, Jiang, LL, Jiang, XS, Jiao, JB, Jiao, Z, Jin, DP, Jin, S, Jing, FF, Kalantar-Nayestanaki, N, Kavatsyuk, M, Kuehn, W, Lai, W, Lange, JS, Li, CH, Li, C, Li, DM, Li, F, Li, G, Li, HB, Li, JC, Li, K, Li, L, Li, QJ, Li, SL, Li, WD, Li, WG, Li, XL, Li, XN, Li, XQ, Li, XR, Li, ZB, Liang, H, Liang, YF, Liang, YT, Liao, GR, Liao, XT, Liu, BJ, Liu, CL, Liu, CX, Liu, CY, Liu, FH, Liu, F, Liu, H, Liu, HH, Liu, HM, Liu, HW, Liu, JP, Liu, KY, Liu, K, Liu, PL, Liu, Q, Liu, SB, Liu, X, Liu, YB, Liu, ZA, Liu, Z, Loehner, H, Lu, GR, Lu, HJ, Lu, JG, Lu, QW, Lu, XR, Lu, YP, Luo, CL, Luo, MX, Luo, T, Luo, XL, Lv, M, Ma, CL, Ma, FC, Ma, HL, Ma, QM, Ma, S, Ma, T, Ma, XY, Ma, Y, Maas, FE, Maggiora, M, Malik, QA, Mao, YJ, Mao, ZP, Messchendorp, JG, Min, J, Min, TJ, Mitchell, RE, Mo, XH, Morales, CM, Motzko, C, Muchnoi, NY, Muramatsu, H, Nefedov, Y, Nicholson, C, Nikolaev, IB, Ning, Z, Olsen, SL, Ouyang, Q, Pacetti, S, Park, JW, Pelizaeus, M, Peng, HP, Peters, K, Ping, JL, Ping, RG, Poling, R, Prencipe, E, Qi, M, Qian, S, Qiao, CF, Qin, XS, Qin, Y, Qin, ZH, Qiu, JF, Rashid, KH, Rong, G, Ruan, XD, Sarantsev, A, Schaefer, BD, Schulze, J, Shao, M, Shen, CP, Shen, XY, Sheng, HY, Shepherd, MR, Song, XY, Spataro, S, Spruck, B, Sun, DH, Sun, GX, Sun, JF, Sun, SS, Sun, YJ, Sun, YZ, Sun, ZJ, Sun, ZT, Tang, CJ, Tang, X, Tapan, I, Thorndike, EH, Toth, D, Ullrich, M, Varner, GS, Wang, B, Wang, BQ, Wang, D, Wang, DY, Wang, K, Wang, LL, Wang, LS, Wang, M, Wang, P, Wang, PL, Wang, Q, Wang, QJ, Wang, SG, Wang, XL, Wang, YD, Wang, YF, Wang, YQ, Wang, Z, Wang, ZG, Wang, ZY, Wei, DH, Wei, JB, Weidenkaff, P, Wen, QG, Wen, SP, Werner, M, Wiedner, U, Wu, LH, Wu, N, Wu, SX, Wu, W, Wu, Z, Xia, LG, Xiao, ZJ, Xie, YG, Xiu, QL, Xu, GF, Xu, GM, Xu, H, Xu, QJ, Xu, XP, Xu, ZR, Xue, F, Xue, Z, Yan, L, Yan, WB, Yan, YH, Yang, HX, Yang, Y, Yang, YX, Ye, H, Ye, M, Ye, MH, Yu, BX, Yu, CX, Yu, HW, Yu, JS, Yu, SP, Yuan, CZ, Yuan, Y, Zafar, AA, Zallo, A, Zeng, Y, Zhang, BX, Zhang, BY, Zhang, C, Zhang, CC, Zhang, DH, Zhang, HH, Zhang, HY, Zhang, JQ, Zhang, JW, Zhang, JY, Zhang, JZ, Zhang, SH, Zhang, XJ, Zhang, XY, Zhang, Y, Zhang, YH, Zhang, YS, Zhang, ZP, Zhang, ZY, Zhao, G, Zhao, HS, Zhao, JW, Zhao, KX, Zhao, L, Zhao, MG, Zhao, Q, Zhao, QZ, Zhao, SJ, Zhao, TC, Zhao, XH, Zhao, YB, Zhao, ZG, Zhemchugov, A, Zheng, B, Zheng, JP, Zheng, YH, Zhong, B, Zhong, J, Zhong, Z, Zhou, L, Zhou, XK, Zhou, XR, Zhu, C, Zhu, K, Zhu, KJ, Zhu, SH, Zhu, XL, Zhu, YC, Zhu, YM, Zhu, YS, Zhu, ZA, Zhuang, J, Zou, BS, Zou, JH, Collaboration, BESIII, Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Fizik Bölümü., and Tapan, İlhan

Subjects
Physics, Astronomy & astrophysics, Physics, particles & fields, Charmonium, Charm (Particle Physics), Mesons
Abstract

The process psi(3686) -> pi(0)h(c), h(c) -> gamma eta(c) has been studied with a data sample of 106 +/- 4 million Psi(3686) events collected with the BESIII detector at the BEPCII storage ring. The mass and width of the P-wave charmonium spin-singlet state h(c)(P-1(1)) are determined by simultaneously fitting distributions of the pi(0) recoil mass for 16 exclusive eta(c) decay modes. The results, M(h(c)) 3525.31 +/- 0.11(stat) +/- 0.14(syst) MeV/c(2) and Gamma(h(c)) = 0.70 +/- 0.28 +/- 0.22 MeV, are consistent with and more precise than previous measurements. We also determine the branching ratios for the 16 exclusive eta(c) decay modes, five of which have not been measured previously. New measurements of the eta(c) line- shape parameters in the E1 transition h(c) -> gamma eta(c) are made by selecting candidates in the h(c) signal sample and simultaneously fitting the hadronic mass spectra for the 16 eta(c) decay channels. The resulting eta(c) mass and width values are M(eta(c)) = 2984.49 +/- 1.16 +/- 0.52 MeV/c(2) and Gamma(eta(c)) 36.4 +/- 3.2 +/- 1.7 MeV. Ministry of Science and Technology, China - 2009CB825200 National Natural Science Foundation of China (NSFC)- 10745001 / 10625524 / 10821063 / 10825524 / 10835001 / 10935007 / 11125525 / 11079008 / 11179007 / 10979058 Chinese Academy of Sciences - KJCX2-YW-N29 / KJCX2-YW-N45 Istituto Nazionale di Fisica Nucleare (INFN) United States Department of Energy (DOE) - DE-FG02-04ER41291 / DE-FG02-91ER40682 / DE-FG02-94ER40823 National Science Foundation (NSF) University of Groningen (RuG) Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt WCU Program of National Research Foundation of Korea - R32-008-000-10155-0 Türkiye Cumhuriyeti Kalkınma Bakanlığı - DPT2006K-120470

Published
2012

23. Cul4A is an oncogene in malignant pleural mesothelioma

Author

Hung, MS, Mao, JH, Xu, Z, Yang, CT, Yu, JS, Harvard, C, Lin, YC, Bravo, DT, Jablons, DM, and You, L

Subjects
Mesothelioma, rho GTP-Binding Proteins, Biochemistry & Molecular Biology, Pleural Neoplasms, Clinical Sciences, amplification, Small Interfering, Cell Line, Medicinal and Biomolecular Chemistry, Rare Diseases, Proliferating Cell Nuclear Antigen, Genetics, Humans, 2.1 Biological and endogenous factors, Aetiology, Lung, Cancer, Tumor, p21, Cell Cycle, Lung Cancer, p27, Oncogenes, Cul4A, Cullin Proteins, respiratory tract diseases, Orphan Drug, RNA, RNA Interference, Biochemistry and Cell Biology, Signal Transduction
Abstract

Cullin 4A (Cul4A) is important in cell survival, development, growth and the cell cycle, but its role in mesothelioma has not been studied. For the first time, we identified amplification of the Cul4A gene in four of five mesothelioma cell lines. Consistent with increased Cul4A gene copy number, we found that Cul4A protein was overexpressed in mesothelioma cells as well. Cul4A protein was also overexpressed in 64% of primary malignant pleural mesothelioma (MPM) tumours. Furthermore, knockdown of Cul4A with shRNA in mesothelioma cells resulted in up-regulation of p21 and p27 tumour suppressor proteins in a p53-independent manner in H290, H28 and MS-1 mesothelioma cell lines. Knockdown of Cul4A also resulted in G0/G1 cell cycle arrest and decreased colony formation in H290, H28 and MS-1 mesothelioma cell lines. Moreover, G0/G1 cell cycle arrest was partially reversed by siRNA down-regulation of p21 and/or p27 in Cul4A knockdown H290 cell line. In the contrary, overexpression of Cul4A resulted in down-regulation of p21 and p27 proteins and increased colony formation in H28 mesothelioma cell line. Both p21 and p27 showed faster degradation rates in Cul4A overexpressed H28 cell line and slower degradation rates in Cul4A knockdown H28 cell line. Our study indicates that Cul4A amplification and overexpression play an oncogenic role in the pathogenesis of mesothelioma. Thus, Cul4A may be a potential therapeutic target for MPM. © 2011 The Authors Journal of Cellular and Molecular Medicine © 2011 Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd.

Published
2011

34. Electrophoresis of DNA in novel thermoreversible matrices

Author

Yu Js, Herbert H. Hooper, Hion Dy, Alexander P. Sassi, David S. Soane, M. G. Alonso-Amigo, and Annelise E. Barron

Subjects
Free-flow electrophoresis, Gel electrophoresis, chemistry.chemical_classification, Electrophoresis, Chromatography, Gel electrophoresis of nucleic acids, Chemistry, Polymers, Viscosity, Clinical Biochemistry, Polyacrylamide, Analytical chemistry, Temperature, Electrophoresis, Capillary, Polymer, DNA, Biochemistry, Microspheres, Analytical Chemistry, chemistry.chemical_compound, Capillary electrophoresis, Agarose, Feasibility Studies, Gels
Abstract

We demonstrate the feasibility of temperature-sensitive polymers as novel matrices for capillary and slab electrophoresis of DNA. These matrices combine the case-of-use of agarose with resolution properties of polyacrylamide. Two classes of matrices are used: (i) aqueous suspensions of gel microspheres and (ii) solutions containing uncross-linked temperature-sensitive polymers. When heated, the viscosity of these solutions drops dramatically because of the phase transition behavior of these polymers, and therefore these formulations are easy to pour or load. Results are presented for separation of double-stranded DNA fragments (< 2000 bp) in capillary, tube, and slab electrophoresis. Preliminary results are also presented for separation of single-stranded sequencing fragments by capillary electrophoresis. In the tube format, good resolution was obtained for phi X174/HaeIII fragments. In the slab format, excellent resolution of double-stranded DNA was obtained, including simultaneous separation of a 10 bp ladder up to 150 base pairs. In the capillary format, pBR322/MspI fragments were completely resolved, and single-base resolution of sequencing fragments was obtained up to 150 bases. We believe that temperature-sensitive polymers represent a new and promising class of electrophoretic media.

Published
1996

36. Radiographic indicators of acute ligament injuries of the knee: a mechanistic approach.

Author

Miller LS, Yu JS, Miller, Lauren S, and Yu, Joseph Sekiguchi

Abstract

Disruption of a knee ligament is one of the most common entities in patients who present with pain after sustaining trauma to this joint. Occasionally, there are indicators of a ligament injury on initial radiographs. However, close inspection of images is required and knowledge of high-risk areas is imperative in order to render the correct diagnosis. Its importance is that initiation of treatment relies on the accuracy of the initial diagnosis. A high acumen is predicated on the understanding that different mechanisms of injury have specific effects on the structures of the knee. The subtlety of avulsion and impaction fractures on radiographs often belies the significance of these finding. The objective of this review is to provide a mechanistic approach to associate the radiographic abnormalities with their anatomic relevance. [ABSTRACT FROM AUTHOR]

Published
2010
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37. Nontumorous arterioportal shunts in the liver: CT and MRI findings considering mechanisms and fate.

Author

Ahn JH, Yu JS, Hwang SH, Chung JJ, Kim JH, Kim KW, Ahn, Jhii-Hyun, Yu, Jeong-Sik, Hwang, Sung Ho, Chung, Jae-Joon, Kim, Joo Hee, and Kim, Ki Whang

Abstract

The intrahepatic non-tumorous arterioportal shunt (APS) is one of the important causes of transient hepatic enhancement differences (THED) on dynamic CT or MRI. Most small APSs are located in the peripheral portion of the liver. Because of the parenchymal distortion in the advanced cirrhotic liver, many small APSs tend to show an amorphous or nodular appearance, making them difficult to distinguish from hypervascular tumors. In addition to the use of dynamic CT or MRI, iso-attenuation densities or iso-intensities on pre-contrast and equilibrium phases, MRI using a liver-specific contrast agent can be useful to characterize the hypervascular pseudolesions. Because there is no difference in water diffusion in the hepatic parenchyma in the region of the APS, diffusion-weighted MRI also has great potential to distinguish non-tumorous shunts from true focal lesions. Larger (>2 cm) APSs of direct arterio-portal venous fistulas from extrinsic insults show typical subcapsular wedge-like THEDs that are only temporarily depicted several months after the traumatic event; most of these THEDs gradually decrease in size or vanish completely. By understanding the nature of non-tumorous APSs, radiologists will be able to provide a more accurate assessment of many THEDs during daily interpretations of CT or MR images of the liver. [ABSTRACT FROM AUTHOR]

Published
2010
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38. Small hypervascular hepatocellular carcinomas: value of "washout" on gadolinium-enhanced dynamic MR imaging compared to superparamagnetic iron oxide-enhanced imaging.

Author

Yu JS, Chung JJ, Kim JH, Kim KW, Yu, Jeong-Sik, Chung, Jae-Joon, Kim, Joo Hee, and Kim, Ki Whang

Abstract

The aim of this study was to retrospectively compare the value of "washout" on dynamic MR imaging with superparamagnetic iron oxide (SPIO)-enhanced imaging features of small hepatocellular carcinoma (HCC). A total of 74 small (5-30 mm) hypervascular HCCs in 42 cirrhotic patients who underwent double contrast material-enhanced MR imaging were evaluated to determine the presence of washout in the portal or equilibrium phase of gadolinium-enhanced dynamic imaging and decreased uptake of SPIO on T2*-weighted imaging. HCCs were verified histologically (n = 13) or by serial follow-up imaging studies (n = 61). According to the size of the lesions, 27 vs. 73% (<10 mm, n = 15; P = 0.016 on McNemar test), 39 vs. 79% (10-14 mm, n = 28; P = 0.002), 50 vs. 93% (15-20 mm, n = 14; P = 0.031), and 82 vs. 100% (>20 mm, n = 17; P = 0.250) of the lesions showed washout vs. decreased SPIO accumulation respectively. The larger the lesion, the higher the prevalence of washout or decreased SPIO uptake (P = 0.004 or P = 0.036, respectively, on Mantel-Haenszel test). In many small hypervascular HCCs up to 2 cm, SPIO-enhanced MR imaging offers essential information for early diagnosis in the absence of washout on dynamic imaging. [ABSTRACT FROM AUTHOR]

Published
2009
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39. Patient selection guidelines in MR-guided focused ultrasound surgery of uterine fibroids: a pictorial guide to relevant findings in screening pelvic MRI.

Author

Yoon SW, Lee C, Cha SH, Yu JS, Na YJ, Kim KA, Jung SG, Kim SJ, Yoon, Sang-Wook, Lee, Chan, Cha, Sun Hee, Yu, Jeong-Sik, Na, Young-Jeong, Kim, Kyoung Ah, Jung, Sang-Geun, and Kim, Seung-Jo

Abstract

Uterine leiomyomas (fibroids), the most common benign tumor in women of childbearing age, can cause symptoms including dysmenorrhea, menorrhagia, urinary symptoms, pain and infertility. Hysterectomy is a common approach to treating uterine fibroids, and less invasive surgical approaches such as myomectomy and uterine artery embolization also have been shown to alleviate symptoms. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is the only totally non-invasive surgical approved method for treating uterine fibroids. In clinical trials, MRgFUS resulted in significant relief of uterine fibroid symptoms. The safe and effective use of MRgFUS is affected by fibroid type and location, position relative to adjacent anatomical structures and the presence of co-existent pelvic disease. Additionally, successful outcomes with MRgFUS have been correlated with the volume of fibroids ablated during the procedure. Thus, selection of patients in whom sufficient fibroid volumes can be treated safely using the MRgFUS system is critical for successful outcomes. The MR images in this pictorial essay provide examples of uterine fibroids for which MRgFUS should be considered and is designed to facilitate the selection of patients for whom MRgFUS is most likely to provide sustained symptom relief. [ABSTRACT FROM AUTHOR]

Published
2008
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40. Adrenocortical oncocytoma displaying intense activity on 18F-FDG-PET: a case report and a literature review.

Author

Kim DJ, Chung JJ, Ryu YH, Hong SW, Yu JS, Kim JH, Kim, Dae Jung, Chung, Jae-Joon, Ryu, Young Hoon, Hong, Soon Won, Yu, Jeong-Sik, and Kim, Joo Hee

Abstract

We report on the 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) findings in a case of adrenocortical oncocytoma, a rare tumor of the adrenal gland with the literature review of other imaging findings including ultrasonography, computed tomography, and magnetic resonance imaging. To our knowledge, there have been no reports published in the English literature about 18F-FDG-PET findings in adrenocortical oncocytoma. [ABSTRACT FROM AUTHOR]

Published
2008
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41. Large (>/=2 cm) non-hypervascular nodules depicted on MRI in the cirrhotic liver: fate and implications.

Author

Yu JS, Chung JJ, Kim JH, and Kim KW

Abstract

AIM: To determine the fate and clinical implication of large (>/=2 cm), non-hypervascular nodules depicted on magnetic resonance imaging (MRI) in the cirrhotic liver.MATERIALS AND METHODS: In 21 patients with cirrhosis (14 hepatitis B, two ethanol abuse, four cryptogenic, one Wilson's disease), 25 large (>/=2 cm in the longest dimension) non-hypervascular nodules were identified on dynamic MRI. The implications for diagnosis of the initial size, contour, and signal characteristics on MRI in addition to patients' age and cause of cirrhosis were assessed in our analysis.RESULTS: Twelve (75%) out of 16 lesions were malignant or potentially-malignant from 14 hepatitis B patients, while seven (78%) of the nine lesions from other patients were benign (p=0.016). The mean age of the patients who had malignant or potentially malignant lesions (57 years) was older than that for the other patients (47 years; p = 0.039). 11le ratio of the short-to-long diameter was higher in malignant or potentially malignant lesions (mean 0.86) than in benign lesions (mean 0.69; p = 0.008). There was no discriminative signal intensity characteristic (p> 0.2 for all factors) that indicated the malignant potential for each non-hypervascular nodule. For all 10 lesions in the hepatitis B patients who were older than 52 years with a short-to-long diameter ratio of more than 0.75, the positive predictive value for malignant potential based on these three combined factors was 100%.CONCLUSION: In older patients with cirrhosis from hepatitits B, large (>/=2 cm), non-hypervascular nodules with .~ spherical contour have a high malignant potential. [ABSTRACT FROM AUTHOR]

Published
2008
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42. Transient hepatic attenuation difference (THAD) following transcatheter arterial chemoembolization for hepatic malignancy: changes on serial CT examinations.

Author

Hwang SH, Yu JS, Chung J, Chung JJ, Kim JH, Kim KW, Hwang, Sung Ho, Yu, Jeong-Sik, Chung, Jin, Chung, Jae-Joon, Kim, Joo Hee, and Kim, Ki Whang

Abstract

The purpose of this study was to investigate the natural history of transcatheter arterial chemoembolization (TACE)-induced, transient hepatic attenuation difference (THAD). Among the patients who underwent TACE for treatment of hepatocellular carcinomas during a 32-month period, 32 patients with 40 newly developed THADs defined as localized, transient, peripheral hepatic parenchymal enhancement during the hepatic arterial phase of dynamic CT (axial dimension, 1.9-8.8 cm; mean, 4.9 cm) in the vicinity of iodized-oil accumulation were subjected to a retrospective analysis of serial follow-up CT examinations. Among the 40 TACE-induced THADs, 18 (45%) and 9 (23%) were accompanied with arterial-portal venous fistula (APF) and portal venous stenosis (PVS), respectively, while 2 (5%) THADs showed both APF and PVS simultaneously. Thirty-eight (95%) THADs disappeared spontaneously during the follow-up period (range, 4-26 months; mean, 9 months), and 11 (29%) of them showed progressive atrophy of the corresponding hepatic parenchyma. Regardless of the presence of APF, 10 (91%) of 11 THADs of following parenchymal atrophy had shown PVSs (P<0.001). During the long-term follow-up period after TACE, almost all of the TACE-induced THADs spontaneously disappeared and either had or did not have corresponding parenchymal atrophy, which is strongly related to the presence of PVS. Understanding the nature of these CT features would be helpful for radiologists in determining the prognosis of the TACE-induced hepatic injuries as well as in distinguishing them from the recurrent tumour. [ABSTRACT FROM AUTHOR]

Published
2008
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44. Recalcitrant patellar tendinitis: magnetic resonance imaging, histologic evaluation, and surgical treatment.

Author

Popp JE, Yu JS, and Kaeding CC

Abstract

Magnetic resonance imaging findings and the results of surgical treatment and histologic evaluation of 11 knees in 9 athletes with recalcitrant patellar tendinitis are reported. All of the athletes had no improvement with traditional nonoperative treatment and all had abnormal magnetic resonance imaging findings consistent with chronic patellar tendinitis. Surgical exploration and debridement were performed on the 11 knees by the same surgeon. With a minimum followup of 1 year, 7 of the 11 knees had excellent results, 3 had good results, and 1 had a poor result. Histologic evaluation of the debrided tissue was consistent with 'angiofibroblastic tendinosis,' which correlated with the abnormal preoperative magnetic resonance imaging findings in the proximal third of the infrapatellar tendon. This study correlated histologic findings with magnetic resonance imaging findings and shows that in selected patients excellent results can be achieved with surgical treatment of recalcitrant patellar tendinitis or 'jumper's knee.' [ABSTRACT FROM AUTHOR]

Published
1997
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45. Wise use of high-tech imaging.

Author

Defilippo J, Totty WG, and Yu JS

Abstract

How do you choose among CT, MRI, and other sophisticated studies? What's new and useful today, and what's cost-efficient? The following guidelines will help you determine which study is best for a wide variety of anatomic sites. [ABSTRACT FROM AUTHOR]

Published
1997

48. Screening tests for metabolic diseases

Author

Yu Js

Subjects
medicine.medical_specialty, Screening test, business.industry, Chromatography, Paper, Phenylalanine, Australia, Infant, Newborn, Infant, General Medicine, Metabolic Diseases, Internal medicine, Phenylketonurias, medicine, Humans, Mass Screening, business, Blood Chemical Analysis, Metabolism, Inborn Errors
Published
1972

49. Changes in the blood viscosity and the consistency of artificial thrombi in 17-year-old girls during the menstrual cycle

Author

Dintenfass L and Yu Js

Subjects
Gynecology, medicine.medical_specialty, Periodicity, Erythrocytes, Adolescent, business.industry, Obstetrics, media_common.quotation_subject, Blood viscosity, Thrombosis, General Medicine, Blood Sedimentation, Blood Viscosity, Menstruation, Hematocrit, Consistency (statistics), Medicine, Humans, Female, Blood Coagulation Tests, business, Menstrual cycle, media_common
Published
1968

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