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1. Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial

Author

Chalmers, James, Abo-Leyah, Hani, New, Benjamin JM, Almaden-Boyle, Christine, Connell, David, Taylor, Jennifer, Strachan, Jodie, Loftus, Heather, Young, Lesley, Strachan, Angela, Band, Margaret, McLaren-Neil, Fiona, Pilvinyte, Kristina, Adamson, Simon, Lahnsteiner, Eva, Rauchhaus, Petra, Hogarth, Fiona, George, Jacob, Burns, Tricia, Coote, Elizabeth, Keiller, Marney, Patel, Manish, Smith, Andrew, Sage, Elizabeth, Cooper, Jamie, Miller, David, Dosanjh, Davinder, Sutton, Benjamin, Underwood, Jonathan, Frayling, Sharon, Haynes, Matthew, Broad, Lauren, Jones, Laura, Rahilly, Karen, Oliver, Catherine, Evans, Terriann, Balan, Andrea, Davies, Rhys, Forde, Donal, Nye, Clemency, Haboubi, Dr, Hilton, Zoe, Williams, Jennie, McQueen, Alison, Spears, Mark, Edmond, Ian, Salutous, Dario, McGenily, Laura, Scott, Rhona, Henderson, Eilidh, Collins, Andrea, Dhasmana, Devesh, Liu, Patrick, Morrow, Ana, Couser, Mandy, Davey, Fleur, Hicks, Alexander, Wiffen, Laura, Fox, Lauren, Abdelrahim, Mohamed, Darbyshire, Alexander, Cowen, Elena, Rowley, Megan, Giles, Benjamin, Yang, Yingjia, Brown, Tom, Rupani, Hitasha, Hawes, Elizabeth, Barnes, Debi, Brogan, Fiona, Bungue-Tuble, Roneleeh, Howe, Serena, Turner, Charlotte, Baryschpolec, Sonia, Longhurst, Bev, Moon, Maria, Watkins, Lynn, Baker-Moffat, Michelle, Murray, Lisa, Harrington-Davies, Yasmin, Burrows, Kate, Minnis, Chrissie, Wands, Mary, Bamgboye, Adefunke, Wong, Charlotte, Brightling, Christopher, Diver, Sarah, Russell, Richard, McAuley, Hamish, Elneima, Omer, Yousuf, Ahmed, McCourt, Paula, Hargadon, Beverley, Parker, Sarah, Bourne, Michelle, Suntharalingam, Jay, Hartley, Tom, Masan, Vidan, Sturney, Sharon, MacKenzie, Rob, Marchand, Clare, Mason, Rebecca, White, Katie, Kirby, Alison, Meda, Manjula, Diwakar, Lavanya, Russell, Peter, Finn, Joanne, Harris, Sophie, Muir, Carol, Cook, Gemma, Staines, Nikki, Cook, Chris, Thompson, AA Roger, Condliffe, Alison, Hull, Rebecca, Dowey, Rebecca, Turton, Helena, Collini, Paul, Gabriel, Zoé, Hardman, Simon, Newell, Helen, Middle, Janet, Simpson, Phillip, Colton, Hayley, Barker, Joann, Birchall, Katie, Harrington, Kate, Housley, Kay, Lenagh, Rebecca, Wilson, Jayne, Wesonga, Joan, Whitham, Rachel, Bird, Sarah, Jackson, Yvonne, Mbuyisa, Angeline, Anderson, Samantha, Wilson, Anna, Kibutu, Faith, Walker, Sara, Cawthron, Kay, Macharia, Irene, Smart, Lynne, Emery, Anna, Howell, Alice, Hurditch, Elizabeth, Ford, Amber, Turner, Kim, Watson, Lisa, Bowler, Helen, Jackson, Tracy, Jaques, Carol, Dyer, Nichole, Ducker, Shelley, Goodall, Vicky, Udale, Emily, Keir, Holly R, Long, Merete B, Giam, Yan Hui, Vadiveloo, Thenmalar, Pembridge, Thomas, Hull, Rebecca C, Delgado, Lilia, Gilmour, Amy, Hughes, Chloe, Richardson, Hollian, Cassidy, Diane, Dosanjh, Davinder PS, Sage, Beth, Condliffe, Alison M, Shoemark, Amelia, MacLennan, Graeme, and Chalmers, James D

Published
2022
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3. Bioengineered small extracellular vesicles deliver multiple SARS‐CoV‐2 antigenic fragments and drive a broad immunological response

Author

Jackson, Hannah K., primary, Long, Heather M., additional, Yam‐Puc, Juan Carlos, additional, Palmulli, Roberta, additional, Haigh, Tracey A., additional, Gerber, Pehuén Pereyra, additional, Lee, Jin S., additional, Matheson, Nicholas J., additional, Young, Lesley, additional, Trowsdale, John, additional, Lo, Mathew, additional, Taylor, Graham S., additional, Thaventhiran, James E., additional, and Edgar, James R., additional

Published
2024
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7. Measurement of left ventricular function in anaesthetised horses using transoesophageal Doppler echocardiography

Author

Young, Lesley Elissa

Subjects
636.089
Abstract

Studies were undertaken using transoesophageal Doppler echocardiography to monitor left ventricular systolic function in anaesthetised horses. A 3.5 MHz transoesophageal probe was specifically developed in collaboration with Vingmed Sound for equine use. The indices of systolic function investigated were maximum acceleration of aortic blood flow (dv/dtmax), maximum blood flow velocity, (Vmax), cardiac output (CO), left ventricular pre-ejection period (PEP) and left ventricular ejection time (ET). The feasibility of the technique was demonstrated in a group of 8 healthy Thoroughbred horses anaesthetised using a standard protocol. It was established that two dimensional transoesophageal echocardiography provided a reference view of the left ventricular outflow tract and aorta that consistently allowed high quality Doppler echocardiographic measurement of aortic blood flow velocity. The flow envelopes obtained were suitable for measurement of indices of left ventricular systolic function. The repeatability of the measured indices was similar to that of the maximum rate of rise of left ventricular pressure (LVdp/dtmax), obtained simultaneously by cardiac catheterisation. Cardiac output estimations made using transoesophageal Doppler echocardiography were compared with those obtained by thermodilution in the same group of horses under general anaesthesia. Cardiac output was altered by infusions of the sympathomimetic amine, dobutamine. Aortic velocity spectra obtained both by high pulse repetition frequency and continuous wave insonation modes were used to obtain the velocity time integral for calculation of cardiac output. The measurements derived from transoesophageal echocardiography agreed well with those obtained by thermodilution. Both correlation coefficients and limits of agreement between the two techniques were better than those obtained from similar studies in standing horses using transthoracic echocardiography. The sensitivity of the Doppler derived indices of left ventricular function on inotropic intervention was assessed in the final sequence of studies. As these indices are derived during the ejection period they are load dependent, so their response to changes in ventricular loading was also assessed and compared with the most commonly used index of myocardial contractility in horses, LVdp/dtmax.

Published
1996

8. Supplementary Figures S1-S5 from A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance

Author

Yap, Timothy A., primary, LoRusso, Patricia M., primary, Wong, Deborah J., primary, Hu-Lieskovan, Siwen, primary, Papadopoulos, Kyriakos P., primary, Holz, Josefin-Beate, primary, Grabowska, Urszula, primary, Gradinaru, Cristian, primary, Leung, Kin-Mei, primary, Marshall, Sylwia, primary, Reader, Claire S., primary, Russell, Roslin, primary, Sainson, Richard C.A., primary, Seal, Claire J., primary, Shepherd, Christopher J., primary, Germaschewski, Fiona, primary, Gliddon, Daniel, primary, Stern, Omer, primary, Young, Lesley, primary, Brewis, Neil, primary, Kayitalire, Louis, primary, and Morrow, Michelle, primary

Published
2023
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9. Supporting information from A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist

Author

Leyland, Rebecca, primary, Watkins, Amanda, primary, Mulgrew, Kathy A., primary, Holoweckyj, Nicholas, primary, Bamber, Lisa, primary, Tigue, Natalie J., primary, Offer, Emily, primary, Andrews, John, primary, Yan, Li, primary, Mullins, Stefanie, primary, Oberst, Michael D., primary, Coates Ulrichsen, Jane, primary, Leinster, David A., primary, McGlinchey, Kelly, primary, Young, Lesley, primary, Morrow, Michelle, primary, Hammond, Scott A., primary, Mallinder, Philip, primary, Herath, Athula, primary, Leow, Ching Ching, primary, Wilkinson, Robert W., primary, and Stewart, Ross, primary

Published
2023
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10. Supporting information tracked changes from A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist

Author

Leyland, Rebecca, primary, Watkins, Amanda, primary, Mulgrew, Kathy A., primary, Holoweckyj, Nicholas, primary, Bamber, Lisa, primary, Tigue, Natalie J., primary, Offer, Emily, primary, Andrews, John, primary, Yan, Li, primary, Mullins, Stefanie, primary, Oberst, Michael D., primary, Coates Ulrichsen, Jane, primary, Leinster, David A., primary, McGlinchey, Kelly, primary, Young, Lesley, primary, Morrow, Michelle, primary, Hammond, Scott A., primary, Mallinder, Philip, primary, Herath, Athula, primary, Leow, Ching Ching, primary, Wilkinson, Robert W., primary, and Stewart, Ross, primary

Published
2023
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11. Supplementary figures from A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist

Author

Leyland, Rebecca, primary, Watkins, Amanda, primary, Mulgrew, Kathy A., primary, Holoweckyj, Nicholas, primary, Bamber, Lisa, primary, Tigue, Natalie J., primary, Offer, Emily, primary, Andrews, John, primary, Yan, Li, primary, Mullins, Stefanie, primary, Oberst, Michael D., primary, Coates Ulrichsen, Jane, primary, Leinster, David A., primary, McGlinchey, Kelly, primary, Young, Lesley, primary, Morrow, Michelle, primary, Hammond, Scott A., primary, Mallinder, Philip, primary, Herath, Athula, primary, Leow, Ching Ching, primary, Wilkinson, Robert W., primary, and Stewart, Ross, primary

Published
2023
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12. Kraman et al Supplementary Data from FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity

Author

Kraman, Matthew, primary, Faroudi, Mustapha, primary, Allen, Natalie L., primary, Kmiecik, Katarzyna, primary, Gliddon, Daniel, primary, Seal, Claire, primary, Koers, Alexander, primary, Wydro, Mateusz M., primary, Batey, Sarah, primary, Winnewisser, Julia, primary, Young, Lesley, primary, Tuna, Mihriban, primary, Doody, Jacqueline, primary, Morrow, Michelle, primary, and Brewis, Neil, primary

Published
2023
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14. Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial

Author

Keir, Holly R, primary, Long, Merete B, additional, Abo-Leyah, Hani, additional, Giam, Yan Hui, additional, Vadiveloo, Thenmalar, additional, Pembridge, Thomas, additional, Hull, Rebecca C, additional, Delgado, Lilia, additional, Band, Margaret, additional, McLaren-Neil, Fiona, additional, Adamson, Simon, additional, Lahnsteiner, Eva, additional, Gilmour, Amy, additional, Hughes, Chloe, additional, New, Benjamin JM, additional, Connell, David, additional, Dowey, Rebecca, additional, Turton, Helena, additional, Richardson, Hollian, additional, Cassidy, Diane, additional, Cooper, Jamie, additional, Suntharalingam, Jay, additional, Diwakar, Lavanya, additional, Russell, Peter, additional, Underwood, Jonathan, additional, Hicks, Alexander, additional, Dosanjh, Davinder PS, additional, Sage, Beth, additional, Dhasmana, Devesh, additional, Spears, Mark, additional, Thompson, AA Roger, additional, Brightling, Christopher, additional, Smith, Andrew, additional, Patel, Manish, additional, George, Jacob, additional, Condliffe, Alison M, additional, Shoemark, Amelia, additional, MacLennan, Graeme, additional, Chalmers, James D, additional, Chalmers, James, additional, Almaden-Boyle, Christine, additional, Taylor, Jennifer, additional, Strachan, Jodie, additional, Loftus, Heather, additional, Young, Lesley, additional, Strachan, Angela, additional, Pilvinyte, Kristina, additional, Rauchhaus, Petra, additional, Hogarth, Fiona, additional, Burns, Tricia, additional, Coote, Elizabeth, additional, Keiller, Marney, additional, Sage, Elizabeth, additional, Miller, David, additional, Dosanjh, Davinder, additional, Sutton, Benjamin, additional, Frayling, Sharon, additional, Haynes, Matthew, additional, Broad, Lauren, additional, Jones, Laura, additional, Rahilly, Karen, additional, Oliver, Catherine, additional, Evans, Terriann, additional, Balan, Andrea, additional, Davies, Rhys, additional, Forde, Donal, additional, Nye, Clemency, additional, Haboubi, Dr, additional, Hilton, Zoe, additional, Williams, Jennie, additional, McQueen, Alison, additional, Edmond, Ian, additional, Salutous, Dario, additional, McGenily, Laura, additional, Scott, Rhona, additional, Henderson, Eilidh, additional, Collins, Andrea, additional, Liu, Patrick, additional, Morrow, Ana, additional, Couser, Mandy, additional, Davey, Fleur, additional, Wiffen, Laura, additional, Fox, Lauren, additional, Abdelrahim, Mohamed, additional, Darbyshire, Alexander, additional, Cowen, Elena, additional, Rowley, Megan, additional, Giles, Benjamin, additional, Yang, Yingjia, additional, Brown, Tom, additional, Rupani, Hitasha, additional, Hawes, Elizabeth, additional, Barnes, Debi, additional, Brogan, Fiona, additional, Bungue-Tuble, Roneleeh, additional, Howe, Serena, additional, Turner, Charlotte, additional, Baryschpolec, Sonia, additional, Longhurst, Bev, additional, Moon, Maria, additional, Watkins, Lynn, additional, Baker-Moffat, Michelle, additional, Murray, Lisa, additional, Harrington-Davies, Yasmin, additional, Burrows, Kate, additional, Minnis, Chrissie, additional, Wands, Mary, additional, Bamgboye, Adefunke, additional, Wong, Charlotte, additional, Diver, Sarah, additional, Russell, Richard, additional, McAuley, Hamish, additional, Elneima, Omer, additional, Yousuf, Ahmed, additional, McCourt, Paula, additional, Hargadon, Beverley, additional, Parker, Sarah, additional, Bourne, Michelle, additional, Hartley, Tom, additional, Masan, Vidan, additional, Sturney, Sharon, additional, MacKenzie, Rob, additional, Marchand, Clare, additional, Mason, Rebecca, additional, White, Katie, additional, Kirby, Alison, additional, Meda, Manjula, additional, Finn, Joanne, additional, Harris, Sophie, additional, Muir, Carol, additional, Cook, Gemma, additional, Staines, Nikki, additional, Cook, Chris, additional, Condliffe, Alison, additional, Hull, Rebecca, additional, Collini, Paul, additional, Gabriel, Zoé, additional, Hardman, Simon, additional, Newell, Helen, additional, Middle, Janet, additional, Simpson, Phillip, additional, Colton, Hayley, additional, Barker, Joann, additional, Birchall, Katie, additional, Harrington, Kate, additional, Housley, Kay, additional, Lenagh, Rebecca, additional, Wilson, Jayne, additional, Wesonga, Joan, additional, Whitham, Rachel, additional, Bird, Sarah, additional, Jackson, Yvonne, additional, Mbuyisa, Angeline, additional, Anderson, Samantha, additional, Wilson, Anna, additional, Kibutu, Faith, additional, Walker, Sara, additional, Cawthron, Kay, additional, Macharia, Irene, additional, Smart, Lynne, additional, Emery, Anna, additional, Howell, Alice, additional, Hurditch, Elizabeth, additional, Ford, Amber, additional, Turner, Kim, additional, Watson, Lisa, additional, Bowler, Helen, additional, Jackson, Tracy, additional, Jaques, Carol, additional, Dyer, Nichole, additional, Ducker, Shelley, additional, Goodall, Vicky, additional, and Udale, Emily, additional

Published
2022
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15. A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance

Author

Yap, Timothy A., primary, LoRusso, Patricia M., additional, Wong, Deborah J., additional, Hu-Lieskovan, Siwen, additional, Papadopoulos, Kyriakos P., additional, Holz, Josefin-Beate, additional, Grabowska, Urszula, additional, Gradinaru, Cristian, additional, Leung, Kin-Mei, additional, Marshall, Sylwia, additional, Reader, Claire S., additional, Russell, Roslin, additional, Sainson, Richard C.A., additional, Seal, Claire J., additional, Shepherd, Christopher J., additional, Germaschewski, Fiona, additional, Gliddon, Daniel, additional, Stern, Omer, additional, Young, Lesley, additional, Brewis, Neil, additional, Kayitalire, Louis, additional, and Morrow, Michelle, additional

Published
2022
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16. Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials

Author

Martin, Sebastin, primary, de Haan, Laura, additional, Miro Estruch, Ignacio, additional, Eder, Kai Moritz, additional, Marzi, Anne, additional, Schnekenburger, Jürgen, additional, Blosi, Magda, additional, Costa, Anna, additional, Antonello, Giulia, additional, Bergamaschi, Enrico, additional, Riganti, Chiara, additional, Beal, David, additional, Carrière, Marie, additional, Taché, Olivier, additional, Hutchison, Gary, additional, Malone, Eva, additional, Young, Lesley, additional, Campagnolo, Luisa, additional, La Civita, Fabio, additional, Pietroiusti, Antonio, additional, Devineau, Stéphanie, additional, Baeza, Armelle, additional, Boland, Sonja, additional, Zong, Cai, additional, Ichihara, Gaku, additional, Fadeel, Bengt, additional, and Bouwmeester, Hans, additional

Published
2022
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17. Pre-validation of a reporter gene assay for oxidative stress for the rapid screening of nanobiomaterials

Author

Martin, Sebastin, de Haan, Laura, Miro Estruch, Ignacio, Eder, Kai Moritz, Marzi, Anne, Schnekenburger, Jürgen, Blosi, Magda, Costa, Anna, Antonello, Giulia, Bergamaschi, Enrico, Riganti, Chiara, Beal, David, Carrière, Marie, Taché, Olivier, Hutchison, Gary, Malone, Eva, Young, Lesley, Campagnolo, Luisa, La Civita, Fabio, Pietroiusti, Antonio, Devineau, Stéphanie, Baeza, Armelle, Boland, Sonja, Zong, Cai, Ichihara, Gaku, Fadeel, Bengt, Bouwmeester, Hans, Martin, Sebastin, de Haan, Laura, Miro Estruch, Ignacio, Eder, Kai Moritz, Marzi, Anne, Schnekenburger, Jürgen, Blosi, Magda, Costa, Anna, Antonello, Giulia, Bergamaschi, Enrico, Riganti, Chiara, Beal, David, Carrière, Marie, Taché, Olivier, Hutchison, Gary, Malone, Eva, Young, Lesley, Campagnolo, Luisa, La Civita, Fabio, Pietroiusti, Antonio, Devineau, Stéphanie, Baeza, Armelle, Boland, Sonja, Zong, Cai, Ichihara, Gaku, Fadeel, Bengt, and Bouwmeester, Hans

Abstract

Engineered nanomaterials have been found to induce oxidative stress. Cellular oxidative stress, in turn, can result in the induction of antioxidant and detoxification enzymes which are controlled by the nuclear erythroid 2-related factor 2 (NRF2) transcription factor. Here, we present the results of a pre-validation study which was conducted within the frame of BIORIMA (“biomaterial risk management”) an EU-funded research and innovation project. For this we used an NRF2 specific chemically activated luciferase expression reporter gene assay derived from the human U2OS osteosarcoma cell line to screen for the induction of the NRF2 mediated gene expression following exposure to biomedically relevant nanobiomaterials. Specifically, we investigated Fe3O4-PEG-PLGA nanomaterials while Ag and TiO2 “benchmark” nanomaterials from the Joint Research Center were used as reference materials. The viability of the cells was determined by using the Alamar blue assay. We performed an interlaboratory study involving seven different laboratories to assess the applicability of the NRF2 reporter gene assay for the screening of nanobiomaterials. The latter work was preceded by online tutorials to ensure that the procedures were harmonized across the different participating laboratories. Fe3O4-PEG-PLGA nanomaterials were found to induce very limited NRF2 mediated gene expression, whereas exposure to Ag nanomaterials induced NRF2 mediated gene expression. TiO2 nanomaterials did not induce NRF2 mediated gene expression. The variability in the results obtained by the participating laboratories was small with mean intra-laboratory standard deviation of 0.16 and mean inter laboratory standard deviation of 0.28 across all NRF2 reporter gene assay results. We conclude that the NRF2 reporter gene assay is a suitable assay for the screening of nanobiomaterial-induced oxidative stress responses.

Published
2022

19. 2012 Moonbuggy Senior Design Project

Author

Fay, Davis, Frohbieter, Alisa, Young, Lesley, and Williams, Ryan

Subjects
Mechanical Engineering, FOS: Mechanical engineering
Abstract

The National Aeronautic Space Administration, NASA, holds an annual student design competition in Huntsville, Alabama called the Great Moonbuggy Race. Students are required to design and build a vehicle that focus on a series of engineering problems similar to those faced by the original Moonbuggy team. The vehicles are raced by two students, one male and one female, around a course including simulated moon terrain. This senior design project includes the complete design of a two passenger, human powered moonbuggy to compete in the 2012 NASA Great Moonbuggy Race. The design includes a frame made of 4130 Chromoly steel tubing. To fit in the specified dimensions, the frame will fold in half at a hinge in the center. Steering will be accomplished by articulation about the center hinge. Riders will sit back-to-back and will power the moonbuggy through basic bicycle components.

Published
2021
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20. List of contributors

Author

ALLEN, KATE, primary, ANDERSON, BRIAN, additional, ART, TATIANA, additional, BARREY, ERIC, additional, BASSAGE, LANCE H., additional, BAYLY, WARWICK, additional, BELL, BRENDON, additional, BERGH, ANNA, additional, BERTONE, ALICIA L., additional, BIRCH, HELEN L., additional, BODEN, LISA, additional, CARR, ELIZABETH A., additional, CHEETHAM, JON, additional, COUETIL, LAURENT L., additional, COUROUCÉ-MALBLANC, ANNE, additional, DANIEL, ALEXANDER J., additional, DUCHARME, NORM G., additional, ELLIS, PATRICIA M., additional, ERICKSON, HOWARD H., additional, FELDMANN, HILLARY, additional, FOREMAN, JONATHAN H., additional, FRANKLIN, SAMANTHA, additional, GEOR, RAYMOND J., additional, GILLIS, CAROL, additional, GIRAUDET, AUDE, additional, GOFF, LESLEY, additional, GOODRICH, LAURIE R., additional, GOODSHIP, ALLEN E., additional, HARDY, JOANNE, additional, HARRIS, PATRICIA A., additional, HAUSSLER, KEVIN K., additional, HINCHCLIFF, KENNETH W., additional, HOLBROOK, TODD C., additional, HOLCOMBE, SUSAN J., additional, HUBBELL, JOHN A.E., additional, IRELAND, JO L., additional, JEFFCOTT, LEO B., additional, JOSE-CUNILLERAS, EDUARD, additional, KANEPS, ANDRIS J., additional, KAWCAK, CHRISTOPHER E., additional, KEEGAN, KEVIN G., additional, KIRKER-HEAD, CARL A., additional, KRAMER, JOANNE, additional, LINDINGER, MICHAEL, additional, LORENZO-FIGUERAS, MIREIA, additional, LUMSDEN, JONATHAN M., additional, McCUTCHEON, L. JILL, additional, MCGOWAN, CATHERINE M., additional, MCKEEVER, KENNETH HARRINGTON, additional, MCKENZIE, ERICA C., additional, MAHER, OMAR, additional, MERRITT, ALFRED M., additional, MORLEY, PAUL S., additional, MURRAY, RACHEL C., additional, NATH, LAURA C., additional, NELSON, BRAD B., additional, NIETO, JORGE, additional, O'SULLIVAN, CHRISTOPHER B., additional, PARKIN, TIM, additional, PIERCY, RICHARD J., additional, PILSWORTH, ROB, additional, POOLE, DAVID C., additional, PUSTERLA, NICOLA, additional, RIGGS, CHRISTOPHER M., additional, RITMEESTER, ANDREA, additional, RIVERO, JOSÉ-LUIS L., additional, ROBERT, CÉLINE, additional, SCHWARZWALD, COLIN C., additional, SINCLAIR, CHARLOTTE, additional, SMITH, ROGER K.W., additional, STEWART, BRIAN D., additional, VAN DER KOLK, JOHANNES H., additional, VAN ERCK-WESTERGREN, EMMANUELLE, additional, VAN LOON, GUNTHER, additional, VAN WEEREN, RENÉ, additional, VOTION, DOMINIQUE, additional, WHITTON, CHRIS, additional, and YOUNG, LESLEY E., additional

Published
2014
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22. Contributors

Author

Amend, Katie S., primary, Bailey, C. Scott, additional, Banse, Heidi, additional, Baratt, Robert M., additional, Barger, Anne, additional, Barton, Michelle Henry, additional, Bassage, Lance H., additional, Beerntsen, Brenda T., additional, Bertone, Alicia L., additional, Birks, Eric K., additional, Bischoff, Karyn, additional, Blissitt, Karen, additional, Bonagura, John D., additional, Bourgeois, Melissa, additional, Brown, Jennifer A., additional, Brumitt, Jason W., additional, Bryan, Jeffrey N., additional, Buhl, Rikke, additional, Burke, Daniel J., additional, Camus, Melinda S., additional, Canisso, Igor Frederico, additional, Carlson, Kelly L., additional, Carmalt, James L., additional, Chew, Leeah R., additional, Childers, Cameon M., additional, Cora, Michelle, additional, Costa, Lais R.R., additional, Coutinho da Silva, Marco A., additional, Couto, Gabriel Borges, additional, Cregar, Laura C., additional, Cruz, Antonio M., additional, Dascanio, John J., additional, Davidson, Elizabeth J., additional, Davis, Heather, additional, DeLorey, Mary S., additional, DeLuca, Catherine A., additional, DeWitt, Shane F., additional, Figueiredo, Monica Dias, additional, Diaw, Mouhamadou K., additional, Di Terlizzi, Roberta, additional, Dowling, Patricia M., additional, Ducharme, Norm G., additional, Dujovne, Ghislaine, additional, Durando, Mary M., additional, Duren, Steven, additional, Earley, Edward T., additional, Eaton, Sarah E., additional, Eggleston, Randy, additional, Elfenbein, Johanna, additional, Ensley, Steve, additional, Epstein, Kira L., additional, Evans, Tim J., additional, Farnsworth, Kelly, additional, Ferrer, Maria S., additional, Ferris, Ryan A., additional, Fidel, Janean L., additional, García-López, José M., additional, Garner, Bridget C., additional, Gaskill, Cynthia L., additional, Gerard, Mathew P., additional, Getman, Liberty M., additional, Gilger, Brian C., additional, Gilliam, Lyndi L., additional, Gilor, Shir, additional, Giuliano, Elizabeth A., additional, Gomez-Ibanez, Sara, additional, Graham-Thiers, Patty, additional, Grand, François-Xavier, additional, Grasperge, Britton, additional, Grondin, Tanya M., additional, Groover, Erin S., additional, Gruntman, Alisha M., additional, Gwaltney-Brant, Sharon, additional, Hanson, R. Reid, additional, Hart, Kelsey A., additional, Haussler, Kevin K., additional, Hawkins, Jan F., additional, Hayden, Shelby, additional, Hayles, Jonathan, additional, Henneke, Don, additional, Hewes, Christina, additional, Hill, Sara A., additional, Hines, Melissa T., additional, Hines, Siddra, additional, Hoff, Brent, additional, Hoffmann, Andrew M., additional, Hoffman, Rhonda M., additional, Holyoak, Gilbert Reed, additional, House, Amanda Martabano, additional, Hurcombe, Samuel D.A., additional, Imerman, Paula M., additional, Jenner, Florien, additional, Jesty, Sophy A., additional, Johnson, Aime K., additional, Johnson, Philip J., additional, Kalf, Kelly L., additional, Kaneps, Andris J., additional, Kawcak, Chris, additional, Keegan, Kevin, additional, King, Alana, additional, Knight, Anthony P., additional, Kramer, Joanne, additional, Krimer, Paula M., additional, Lane, Laura V., additional, Lascola, Kara M., additional, Lawrence, Laurie M., additional, Lefebvre, Rejean Cléophas, additional, Londoño, Alfredo Sanchez, additional, Long, Maureen T., additional, Love, Charles C., additional, Mair, Tim, additional, Makloski, Chelsea, additional, Mattoon, John S., additional, Mazan, Melissa R., additional, Montilla, Hernán J., additional, Morgan, Sandra E., additional, Morresey, Peter R., additional, Mostrom, Michelle S., additional, Munsterman, Amelia, additional, Murphy, Lisa A., additional, Murphy, Mike, additional, Neelis, Dana A., additional, Nolen-Walston, Rose, additional, Norton, Joan, additional, Nout, Yvette S., additional, Passler, Nicole H., additional, Paxson, Julia A., additional, Pearson, Erwin G., additional, Pearson, Lisa K., additional, Pellegrini-Masini, Alessandra, additional, Petersen, Annette, additional, Pinto, Nelson I., additional, Piperisova, Ida, additional, Plough, Tracy, additional, Puchalski, Sarah M., additional, Puschner, Birgit, additional, Raggio, Ignacio, additional, Raisbeck, Merl F., additional, Reed, Stephen M., additional, Reilly, Thomas J., additional, Renschler, Janelle S., additional, Rizzi, Theresa E., additional, Roberts, Gregory D., additional, Rodriguez, Jacobo S., additional, Royal, Angela B., additional, Samper, Juan C., additional, Sampieri, Francesca, additional, Santschi, Elizabeth M., additional, Sardoy, Maria Clara, additional, Sathe, Swanand R., additional, Schommer, Susan, additional, Schumacher, John, additional, Schwarzwald, Colin C., additional, Diaz, Olga Seco, additional, Seino, Kathy K., additional, Sellon, Debra C., additional, Selting, Kim A., additional, Senter, David, additional, Sherlock, Ceri, additional, Siciliano, Paul D., additional, Smith, Phoebe A., additional, Snyder, Laura Ann, additional, Stashak, Ted S., additional, Stewart, Allison J., additional, Stull, Carolyn L., additional, Sullins, Kenneth E, additional, Sutter, W. Wesley, additional, Taintor, Jennifer, additional, Talcott, Patricia A., additional, Tennent-Brown, Brett, additional, Théorêt, Christine, additional, Tibary, Ahmed, additional, Timoney, Peter J., additional, Tizard, Ian, additional, Toribio, Ramiro E., additional, Tripp, Chelsea D., additional, Troedsson, Mats H.T., additional, Valentine, Beth A., additional, van Loon, Gunther, additional, Velde, Karsten, additional, Voelkl, Dawna L., additional, Waldridge, Bryan M., additional, Warren, Lori K., additional, Weber, Kimberly, additional, Whitney, Marlyn S., additional, Wiedmeyer, Charles, additional, Wilborn, Robyn R., additional, Wilkins, Pamela, additional, Wilkinson, Tom, additional, Williams, Carey A., additional, Williams, Jarred, additional, Wimer, Christine L., additional, Wise, L. Nicki, additional, and Young, Lesley E., additional

Published
2012
Full Text
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24. Contributors

Author

Bain, Fairfield T., primary, Blissitt, Karen, additional, Bowen, Mark, additional, McIntosh Bright, Janice, additional, Cox, Alistair, additional, Durando, Mary, additional, Elliott, Jonathan, additional, Evans, David, additional, Fogerty, Ursula, additional, Foote, Alastair, additional, van Loon, Gunther, additional, Hallowell, Gayle, additional, Keen, John, additional, Marr, Celia M., additional, Milne, Elspeth, additional, Mogg, Tony D., additional, de Solis, Cristobal Navas, additional, Patteson, Mark, additional, Piercy, Richard, additional, Reef, Virginia, additional, Reimer, Johanna, additional, Robertson, Sheilah, additional, Sage, Abby, additional, Seco, Olga, additional, Thomas, William, additional, Underwood, Claire, additional, and Young, Lesley, additional

Published
2010
Full Text
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27. 446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition

Author

Joyce, Peter, primary, Young, Lesley, additional, Quibell, Martin, additional, Shiers, Jason, additional, Tong, Carmen, additional, Clark, Kristopher, additional, James, Edd, additional, Reeves, Emma, additional, Remtulla, Alihussein, additional, Leonard, Henry, additional, Almeida, Camila de, additional, Lori, Elisa, additional, Ternette, Nicola, additional, Poynton, Fergus, additional, and Leishman, Andrew, additional

Published
2020
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28. Abstract 5551: Potent oral ERAP1 inhibitors modify the immunopeptidome in vivo and are novel immunotherapy agents

Author

Ware, Jamie, primary, McIntyre, Patrick, additional, Clark, Kristopher, additional, Tong, Carmen, additional, Shiers, Jason, additional, Lori, Elisa, additional, de Almeida, Camila, additional, Reeves, Emma, additional, Leonard, Henry, additional, Remtulla, Alihussein, additional, Ford, Michael, additional, Ternette, Nicola, additional, Poynton, Fergus, additional, James, Edd, additional, Young, Lesley, additional, Quibell, Martin, additional, and Joyce, Peter I., additional

Published
2020
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29. FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity

Author

Kraman, Matthew, primary, Faroudi, Mustapha, additional, Allen, Natalie L., additional, Kmiecik, Katarzyna, additional, Gliddon, Daniel, additional, Seal, Claire, additional, Koers, Alexander, additional, Wydro, Mateusz M., additional, Batey, Sarah, additional, Winnewisser, Julia, additional, Young, Lesley, additional, Tuna, Mihriban, additional, Doody, Jacqueline, additional, Morrow, Michelle, additional, and Brewis, Neil, additional

Published
2020
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30. Is your body ready for a baby?

Author

Young, Lesley

Subjects
Pregnancy -- Planning, Pregnancy -- Health aspects, Pregnant women -- Food and nutrition, Pregnant women -- Health aspects, Risk factors (Health) -- Evaluation, Physical fitness -- Methods, Company business planning, Food/cooking/nutrition, Home and garden
Published
2010

33. Tailored glamour

Author

Young, Lesley

Subjects
Architecture, Domestic -- Evaluation, Christmas decorations -- Usage, Architecture and design industries, Home and garden
Published
2009

34. Arthritis: what women need to know

Author

Young, Lesley

Subjects
Pain -- Care and treatment, Pain -- Methods, Arthritis -- Prevention, Arthritis -- Care and treatment, Arthritis -- Diagnosis, Women -- Health aspects, Women -- Evaluation, Food/cooking/nutrition, Home and garden
Published
2009

39. A hard lesson

Author

Young, Lesley

Subjects
Advertising and children -- Psychological aspects, Advertising and children -- Public opinion, Parents -- Surveys, Advertising, marketing and public relations, Business, Business, international
Abstract

Marketers argue that they are correcting their advertising practices aimed at children, however, a Today's Parent and Marketing survey revealed that 36% of nearly 3,000 Canadian parents want to see advertising to children banned. Parents fear that advertising has a negative effect on children's mind. Parents' perceptions on advertising to kids are analyzed further.

Published
2008

41. Fore play: a poseur's guide to looking good on the links

Author

Davey, Alanna, McGrenere, Tim, McPherson, David, Robbeson, David, and Young, Lesley

Subjects
Golfers -- Homes and haunts, Golf courses -- Services, Country clubs -- Services
Abstract

Don't know a mulligan from a mashie-niblick? Neither do we. But we asked, and though golf gurus have zero patience for wannabes, we were pushy. Here, the basics of what […]

Published
2008

42. Sleep well, be well

Author

Young, Lesley

Subjects
Sleep -- Health aspects, Sleep disorders -- Research, Sleep disorders -- Health aspects, Insomnia -- Statistics, Insomnia -- Management, Women -- Health aspects, Women -- Research, Company business management, Food/cooking/nutrition, Home and garden
Published
2008

47. Homeopathy: could it work for you

Author

Young, Lesley

Subjects
Homeopathy -- Usage, Homeopathy -- Health aspects, Homeopathy -- Laws, regulations and rules, Canadians -- Health aspects, Health care coalitions -- Standards, Medical policy -- Laws, regulations and rules, Homeopathy -- Materia medica and therapeutics, Government regulation, Food/cooking/nutrition, Home and garden
Published
2007

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