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14 results on '"Yoshimoto, Sakiya"'

1. A case of rapid amelioration of hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis treated by interferon-free directly acting antivirals for HCV in the absence of immunosuppressant

Author

Obata, Fumiaki, Murakami, Taichi, Miyagi, Junko, Ueda, Sayo, Inagaki, Taizo, Minato, Masanori, Ono, Hiroyuki, Nishimura, Kenji, Shibata, Eriko, Tamaki, Masanori, Yoshimoto, Sakiya, Kishi, Fumi, Kishi, Seiji, Matsuura, Motokazu, Nagai, Kojiro, Abe, Hideharu, and Doi, Toshio

Published
2017
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3. Urinary Exosomal mRNA of WT1 as Diagnostic and Prognostic Biomarker for Diabetic Nephropathy

Author

Abe, Hideharu, Sakurai, Akiko, Ono, Hiroyuki, Hayashi, Sanae, Yoshimoto, Sakiya, Ochi, Arisa, Ueda, Sayo, Nishimura, Kenji, Shibata, Eriko, Tamaki, Masanori, Kishi, Fumi, Kishi, Seiji, Murakami, Taichi, Nagai, Kojiro, and Doi, Toshio

Subjects
diabetic nephropathy, exosome, biomarker, urologic and male genital diseases, PDSTF, WT1
Abstract

Diabetic nephropathy (DN) is the major cause of end-stage renal failure and is associated with increased morbidity and mortality as compared to other causes of renal disease. Albuminuria is often the first clinical indicator of the presence of DN. However, albuminuria or proteinuria is a common symptom in patients with various renal disorders. Therefore, specific biomarkers for the diagnosis of DN are required. A primary hallmark of DN is the progressive damage and death of glomerular podocytes, resulting in the leaking of proteins into the urine. Urinary exosomes released by podocytes are microvesicles containing information of the originated cells. Podocyte-derived signal transduction factors (PDSTFs) are good candidates to assess podocyte injuries. The profile of PDSTFs in urinary exosomes from patients with DN is different from that from patients with minimal change nehrotic syndrome. In addition, PDSTFs molecules in exosomes were derived from primary murine podocytes under high glucose conditions. Among PDSTFs in urinary exosomes, Wilms tumor 1 (WT1) levels reflected damage of diabetic glomeruli in the patients. Urinary exosomal WT1 can predict the decline in eGFR for the following several years. In conclusion, urinary exosomal WT1 is a useful biomarker to improve risk stratification in patients with DN.

Published
2018

5. 至適透析や溶血回避のための血液ポンプ前の動脈圧の再評価 : 血液透析患者における血液ポンプ前の動脈圧モニタリングの重要性

Author

Shibata, Eriko, Nagai, Kojiro, Takeuchi, Risa, Noda, Yasuhiro, Makino, Tomomi, Chikata, Yusuke, Hann, Michael, Yoshimoto, Sakiya, Ono, Hiroyuki, Ueda, Sayo, Tamaki, Masanori, Murakami, Taichi, Matsuura, Motokazu, Abe, Hideharu, and Doi, Toshio

Subjects
Vacuum monitor, Prepump arterial pressure, Blood flow, pressure pillow, Hemolysis, Dialysis
Abstract

Pre-pump arterial pressure (PreAP) is monitored to avoid generating excessive negative pressure. National Kidney Foundation K/DOQI clinical practice guidelines for vascular access recommend that PreAP should not fall below-250 mmHg because excessive negative PreAP can lead to a decrease in the delivery of blood flow, inadequate dialysis, and hemolysis. Nonetheless, these recommendations are consistently disregarded in clinical practice and pressure sensors are often removed from the dialysis circuit.Thus far,delivered blood flow has been reported to decrease at values more negative than -150 mmHg of PreAP. These values have been analyzed by an ultrasonic flowmeter and not directly measured. Furthermore, no known group has evaluated whether PreAP-induced hemolysis occurs at a particular threshold. Therefore, the aim of this study was to clarify the importance of PreAP in the prediction of inadequate dialysis and hemolysis. By using different diameter needles, human blood samples from healthy volunteers were circulated in a closed dialysis circuit. The relationship between PreAP and delivered blood flow or PreAP and hemolysis was investigated. We also investigated the optimal value for PreAP using several empirical monitoring methods, such as a pressure pillow. Our investigation indicated that PreAP is a critical factor in the determination of delivered blood flow and hemolysis,both of which occured at pressure values more negative than -150 mmHg. With the exception of direct pressure monitoring, commonly used monitoring methods for PreAP were determined to be ineffective. We propose that the use of a vacuum monitor would permit regular measurement of PreAP.

Published
2015

6. 入院慢性腎臓病患者における血清アルブミン濃度に影響を与える因子

Author

Yoshimoto, Sakiya, Nagai, Kojiro, Shibata, Eriko, Ueda, Sayo, Ono, Hiroyuki, Tamaki, Masanori, Nishimura, Kenji, Obata, Fumiaki, Inagaki, Taizo, Minato, Masanori, Kishi, Fumi, Matsuura, Motokazu, Matsui, Naoko, Endo, Itsuro, Hann, Michael, Kishi, Seiji, Murakami, Taichi, Abe, Hideharu, and Doi, Toshio

Subjects
Hospitalization, Proteinuria, Postural change, Serum albumin concentration, Chronic kidney disease
Published
2017

7. Progressive renal insufficiency related to ALK inhibitor, alectinib

Author

Nagai, Kojiro, primary, Ono, Hiroyuki, additional, Matsuura, Motokazu, additional, Hann, Michael, additional, Ueda, Sayo, additional, Yoshimoto, Sakiya, additional, Tamaki, Masanori, additional, Murakami, Taichi, additional, Abe, Hideharu, additional, Ishikura, Hisashi, additional, and Doi, Toshio, additional

Published
2018
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8. Shunt Nephritis and Pyogenic Spondylitis With a Positive PR3-ANCA Associated With Chronically Infected Ventriculoatrial Shunt

Author

Ono, Hiroyuki, Kishi, Seiji, Inagaki, Taizo, Mizusawa, Masako, Kishi, Fumi, Yoshimoto, Sakiya, Tamaki, Masanori, Minato, Masanori, Ueda, Sayo, Murakami, Taichi, Nagai, Kojiro, Abe, Hideharu, Doi, Toshio, Ono, Hiroyuki, Kishi, Seiji, Inagaki, Taizo, Mizusawa, Masako, Kishi, Fumi, Yoshimoto, Sakiya, Tamaki, Masanori, Minato, Masanori, Ueda, Sayo, Murakami, Taichi, Nagai, Kojiro, Abe, Hideharu, and Doi, Toshio

Published
2017

9. Successful treatment of highly advanced immunoglobulin G4-related kidney disease presenting renal mass-like regions with end-stage kidney failure: a case study

Author

Ono, Hiroyuki, primary, Murakami, Taichi, additional, Mima, Akira, additional, Shibata, Eriko, additional, Tamaki, Masanori, additional, Yoshimoto, Sakiya, additional, Ueda, Sayo, additional, Kishi, Fumi, additional, Kishi, Seiji, additional, Kawanaka, Takashi, additional, Matsuura, Motokazu, additional, Nagai, Kojiro, additional, Abe, Hideharu, additional, Harada, Masashi, additional, and Doi, Toshio, additional

Published
2017
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10. Shunt Nephritis and Pyogenic Spondylitis With a Positive PR3-ANCA Associated With Chronically Infected Ventriculoatrial Shunt

Author

Ono, Hiroyuki, primary, Kishi, Seiji, additional, Inagaki, Taizo, additional, Mizusawa, Masako, additional, Kishi, Fumi, additional, Yoshimoto, Sakiya, additional, Tamaki, Masanori, additional, Minato, Masanori, additional, Ueda, Sayo, additional, Murakami, Taichi, additional, Nagai, Kojiro, additional, Abe, Hideharu, additional, and Doi, Toshio, additional

Published
2017
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11. Influential factors on serum albumin concentration in hospitalized chronic kidney disease patients

Author

Yoshimoto, Sakiya, primary, Nagai, Kojiro, additional, Shibata, Eriko, additional, Ueda, Sayo, additional, Ono, Hiroyuki, additional, Tamaki, Masanori, additional, Nishimura, Kenji, additional, Obata, Fumiaki, additional, Inagaki, Taizo, additional, Minato, Masanori, additional, Kishi, Fumi, additional, Matsuura, Motokazu, additional, Matsui, Naoko, additional, Endo, Itsuro, additional, Hann, Michael, additional, Kishi, Seiji, additional, Murakami, Taichi, additional, Abe, Hideharu, additional, and Doi, Toshio, additional

Published
2017
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12. Re-recognition of Age-dependent Reference Range for the Serum Creatinine Level in Teenagers - A Case of Slowly Progressive Tubulointerstitial Nephritis which Occurred in an Adolescent -

Author

Ono, Hiroyuki, primary, Nagai, Kojiro, additional, Shibata, Eriko, additional, Matsuura, Motokazu, additional, Kishi, Seiji, additional, Inagaki, Taizo, additional, Minato, Masanori, additional, Yoshimoto, Sakiya, additional, Ueda, Sayo, additional, Obata, Fumiaki, additional, Nishimura, Kenji, additional, Tamaki, Masanori, additional, Kishi, Fumi, additional, Murakami, Taichi, additional, Abe, Hideharu, additional, Kinoshita, Yukiko, additional, Urushihara, Maki, additional, Kagami, Shoji, additional, and Doi, Toshio, additional

Published
2017
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13. A case of rapid amelioration of hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis treated by interferon-free directly acting antivirals for HCV in the absence of immunosuppressant

Author

Obata, Fumiaki, primary, Murakami, Taichi, additional, Miyagi, Junko, additional, Ueda, Sayo, additional, Inagaki, Taizo, additional, Minato, Masanori, additional, Ono, Hiroyuki, additional, Nishimura, Kenji, additional, Shibata, Eriko, additional, Tamaki, Masanori, additional, Yoshimoto, Sakiya, additional, Kishi, Fumi, additional, Kishi, Seiji, additional, Matsuura, Motokazu, additional, Nagai, Kojiro, additional, Abe, Hideharu, additional, and Doi, Toshio, additional

Published
2016
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14. Effects of adiponectin on growth and differentiation of human keratinocytes—Implication of impaired wound healing in diabetes

Author

Kawai, Kenichiro, primary, Kageyama, Akiko, additional, Tsumano, Tomoko, additional, Nishimoto, Soh, additional, Fukuda, Kenji, additional, Yokoyama, Shigekazu, additional, Oguma, Takashi, additional, Fujita, Kazutoshi, additional, Yoshimoto, Sakiya, additional, Yanai, Ayako, additional, and Kakibuchi, Masao, additional

Published
2008
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