6 results on '"Yoshimitsu Kataoka"'
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2. Urinary Excretion of Terminal Complement Complexes in Glomerular Disease
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Noritomo Itami, Yasushi Nagata, Akira Sagawa, Hiroyuki Tochimaru, Yasuo Takekoshi, Yukihiro Kusunoki, Shigeharu Nagasawa, Yasushi Akutsu, and Yoshimitsu Kataoka
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Glomerulonephritis, Membranoproliferative ,Kidney Glomerulus ,Lupus nephritis ,Renal function ,Complement Membrane Attack Complex ,urologic and male genital diseases ,Glomerulonephritis, Membranous ,Excretion ,Heavy proteinuria ,Internal medicine ,Membranoproliferative glomerulonephritis ,medicine ,Humans ,Minimal change disease ,Child ,Glomerulosclerosis, Focal Segmental ,business.industry ,Glomerulonephritis, IGA ,Glomerulonephritis ,Middle Aged ,medicine.disease ,Lupus Nephritis ,female genital diseases and pregnancy complications ,Endocrinology ,Female ,Kidney Diseases ,business ,Nephritis - Abstract
To evaluate renal terminal complement activation in patients with glomerular diseases, we measured terminal complement complexes (TCCs) in plasma and urine with sandwich enzyme-linked immunosorbent assay (ELISA) using a monoclonal antibody against a C9 neoepitope expressed on TCC and a polyclonal antihuman C7 antibody. TCCs were detectable in plasma but not in urine in most of normal controls. In plasma, TCC levels were elevated in 4 of 22 patients with lupus nephritis and in 6 of 12 with membranoproliferative glomerulonephritis. However all patients with IgA nephritis, focal glomerulosclerosis, idiopathic membranous nephritis and idiopathic minimal change nephrotic syndrome (MC) showed normal values. In urine, TCCs were detectable in almost all patients with heavy proteinuria (greater than or equal to 100 mg/ml) except MC. The TCCs present in urine were partially purified by gel filtration using Sepharose 6B and were found to contain C5, C6, C7, C8, C9 and S protein by ELISA. Although the molecular weight of TCC is similar to that of IgM, the fractional excretion rate of TCC was about 100 times higher than that of IgM. These results suggest that TCCs detectable in urine contain SC5b-9 complexes and are mostly of renal origin.
- Published
- 1991
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3. Terminal complement complex in hemodialysis patients treated with different hemodialysis membranes
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Takahiro Ueda, Tetsuo Sakurai, Sawako Fukazawa, Youji Niida, Tetsuo Hirano, Yoshimitsu Kataoka, Mineo Horiguchi, Yoshinori Matsuo, Yasuo Takekoshi, Kazue Yasuda, Yumiko Gotoh, and Tohru Azuma
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chemistry.chemical_compound ,Biocompatibility ,chemistry ,Polysulfone ,eval ,Nuclear chemistry - Abstract
各種透析膜の生体適合性を知るために血中terminal complement complex (TCC) 濃度を測定した. 維持透析患者20名 (男10名, 女10名) を対象として, 再生セルロース (Cu) 膜を10名, 合成膜としてEthylenvinylalcohol (EVAL) 膜を7名, Polysulfone (PS) 膜を3名, 合計10名に使用した. 各透析患者の透析前の血液回路動脈側, 透析開始30分後, 2時間後, 4時間後に静脈側より採血し, TCC濃度をモノクロナール抗体を用いELISA法で測定した.血中TCC濃度はCu膜ではEVAL膜やPS膜の合成膜と異なり透析開始30分後より有意に上昇し, 2時間後にピークとなり4時間後もなお高値を持続した. 一方, EVAL膜, PS膜との間に有意な差を認めなかった. 透析患者でのTCC濃度の測定は, 透析膜の生体適合性を評価すう際の有力なマーカーの一つになり得ると考えられた.
- Published
- 1993
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4. Free <scp>d</scp>-amino acids in human plasma in relation to senescence and renal diseases
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Yoko Nagata, Toyoaki Akino, Takahiro Ueda, Tetsuo Sakurai, Koh-Ichi Shiroshita, Kimiyoshi Ohno, Takuji Yasuda, and Yoshimitsu Kataoka
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Adult ,Male ,Senescence ,Aging ,medicine.medical_specialty ,Renal function ,chemistry.chemical_compound ,Glomerulonephritis ,Internal medicine ,medicine ,Humans ,Amino Acids ,Aged ,chemistry.chemical_classification ,Creatinine ,Acid level ,biology ,business.industry ,Metabolic disorder ,Stereoisomerism ,General Medicine ,Middle Aged ,medicine.disease ,biology.organism_classification ,Amino acid ,Endocrinology ,chemistry ,Human plasma ,Tasa ,Female ,beta 2-Microglobulin ,business ,Glomerular Filtration Rate - Abstract
1. Minute but appreciable amounts of d-amino acids were detected in normal human plasma. 2. The content was significantly higher in an elderly population (age 76 ± 6 years, mean ± sd, n = 41) than in a younger group (age 42 ± 4 years, n = 26), i.e. 6.9 ± 4.8 nmol/ml (mean ± sd, range 0–18.8 nmol/ml) and 2.5 ± 1.8 nmol/ml (range 0–6.3 nmol/ml) for the elderly and the younger groups, respectively. 3. Elevation of plasma d-amino acid level was observed in a group of patients with renal disease (3.6–52.6 nmol/ml), in proportion to the serum level of creatinine (n = 50, r = 0.726, P < 0.001), β2-microglobulin (n = 34, r = 0.551, P < 0.005), and to glomerular filtration rate (n = 39, r = 0.556, P < 0.001).
- Published
- 1987
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5. Role of HLA in IgA nephropathy
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Miki Aizawa, Koji Hamada, Akemi Wakisaka, T. Okuyama, Noboru Kashiwagi, Reiko Miyamoto, Hitoshi Ikeda, Masanori Kasahara, Setsuya Naito, Yoshiyuki Hiki, T Takenouchi, Yoshimitsu Kataoka, Kazumasa Ogasawara, Masaki Kohara, and N. Ishikawa
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Male ,Pathology ,medicine.medical_specialty ,HLA-A Antigens ,business.industry ,Immunology ,Histocompatibility Antigens Class II ,Human leukocyte antigen ,HLA-C Antigens ,medicine.disease ,Pathology and Forensic Medicine ,Nephropathy ,Immunoglobulin A ,Glomerulonephritis ,Antigen ,Japan ,HLA Antigens ,HLA-B Antigens ,medicine ,HLA-DR4 Antigen ,Immunology and Allergy ,Humans ,Female ,business - Abstract
One hundred and four Japanese patients with IgA nephropathy were typed for HLA-A, HLA-B, and HLA-C antigens, and 75 of them were tested for HLA-D region antigens. A significant association was found only with HLA-DR4 (corrected P
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- 1982
6. Book Review / Announcement
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Kazuhisa Mitsuo, Fumitake Gejyo, Antonio Siciliano, Yoko Nagai, Izzet Bariş, Patricia C.K. Chan, Akira Okasho, Jerome F. Levine, Masanobu Ueda, Yves Pirson, T. Kuroume, Boyd Josef Gimnicher Strauss, Carlos Caramelo, Shigehiko Kamoshita, Şali Çaglar, Y. Ushijima, Masaaki Arakawa, V. Parameswaran, Robert Steadman, Haruo Hisazumi, Hiroki Maruyama, Michinobu Hatano, Robert C. Atkins, S.S. Asghar, Hideto Sakai, Lane J. Brunner, L. Arisz, T. Jogestrand, Ikuo Miyagawa, G.T. Venneker, Bernard Jones, Mohamed-Ahdy Saad, Kazuhiko Eguchi, Heikki Helin, Giuliano Barsotti, George Tsapas, L.-E. Lins, D.G. Struijk, J.M.T. Hamilton-Miller, Giovambattista Capasso, Kevin V. Lemley, Murat Sayin, W. Proesmans, Eiji Higashihara, Yukio Hyodo, Reda M. R. Ramzy, Ken Sakai, Akira Hasegawa, R. Baillod, Wilhelm Kriz, Yasuhiko Tomino, Lluis Revert, Natale G. DeSanto, Karen Salamon, Man S. Oh, Soichiro Doi, Ignatius K.P. Cheng, Jörgen Wieslander, Bjarne M. Iversen, Ingegjerd Sekse, André Geubel, K. Maruyama, Gabriel Lopez-Berestein, Turgay Arinsoy, S. Samad, Hidehiko Kawato, André M. Deelder, G.C.M. Koomen, Fatma Moustafa, Yoshimitsu Kataoka, Christiane Pecher, Keizo Imai, Manuel Moliz, Conception Vega Vidalle, Jean Pierre Girolami, Kenjiro Tanaka, Koichi Matsumoto, Yasushi Akutsu, William Black, Alberto Ortiz, Akira Sagawa, Jukka Mustonen, S.K. Pehrsson, Yasuo Takekoshi, Margaret Stein, Masanobu Miyazaki, W.A. Al-Wali, Masayuki Endoh, Ching-Yuang Lin, Per Alm, Janice M. Knowlden, K.J. Van Acker, Konstantinos Mavromatidis, H. Bucht, S. Tomizawa, Albert Adam, David R. Luke, P. Heering, Salvatore Coppola, Shigeharu Nagasawa, Kurt L. Berens, Keiko Nakajima, Takeshi Kosugi, Isamu Motoi, Nurol Arik, Kyoko Hagishima, Juan Ramón Ayuso, Roald Matre, Daniel B. Stroud, Nicholas Topley, John D. Williams, B. Grabensee, Shoji Hirano, Hugh C. Rayner, L. Bellini, Osamu Kida, Takashi Igarashi, Guillermina Blum, Yasuo Nomoto, Jiri J. Frohlich, Hiroyuki Tochimaru, Yasushi Nagata, Kishor M. Wasan, Tomoko Suzuki, Mary S.M. Ip, R. Donckerwolcke, R.T. Krediet, Sonoo Mizuiri, Amos Pasternack, L. Yu, Mitsuo Ohkawa, H. Arai, Jean Pierre Moatti, N.C.A.J. van de Kar, Konstantinos Paletas, Tung-Po Huang, Toru Hyodo, Mohamed A. Sobh, Kazuhiko Shibuya, Y. Seki, Concepción Bru, Jarle Ofstad, Pietro Anastasio, Ole Torffvit, Ploos van Amstel, Regina R. Verani, P. Reekers, S. Rekola, Semra Dündar, Ifigenia Magoula, Jean Loup Bascands, Yoshitaka Yamamoto, Çetin Turgan, Mohamed A. Ghoneim, Kazuo Kitamura, M. Suthanihiran, Oktay Özdemir, N. Clyne, Naoto Yokota, Jean Michel Suc, Sadao Kawamura, L. Monnens, Carl-David Agardh, Jaume Almirall, Yukihiro Kusunoki, Andrew Pomrantz, Kiumars Vadiei, Masami Ishibashi, Ilgar Tasdemir, Ünal Yasavul, Takatomo Morita, Eric Goffin, M. Segasothy, Ruth Mackenzie, Tsutomu Koumi, J.D. Robinson, van Ypersele de Strihou, Johji Kato, W. Brumfitt, C.Y. Chan, E. Wolff, Takehiro Ohara, J. Ekholm, E Ponz, Markku Korpela, Mariangela Policastro, Juan J. Plaza, Tanenao Eto, Alex B. Magil, Sidney C.F. Tam, Amir Tejani, Ikuko Hayashi, A. Bergstrand, Koji Ono, Kazuhiko Kodani, Noritomo Itami, Sergio Giovannetti, Mark L Wahlqvist, and Napier M. Thomson
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business.industry ,Medicine ,business ,Classics - Published
- 1987
- Full Text
- View/download PDF
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