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284 results on '"Yoshimitsu, Masanori"'

2. Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub-analysis of the HiSCO-04 study

Author

Bekki, Tomoaki, Shimomura, Manabu, Saito, Yasufumi, Nakahara, Masahiro, Adachi, Tomohiro, Ikeda, Satoshi, Shimizu, Yosuke, Kochi, Masatoshi, Ishizaki, Yasuyo, Yoshimitsu, Masanori, Takakura, Yuji, Shimizu, Wataru, Sumitani, Daisuke, Kodama, Shinya, Fujimori, Masahiko, Oheda, Mamoru, Kobayashi, Hironori, Akabane, Shintaro, Yano, Takuya, and Ohdan, Hideki

Published
2024
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3. Survival outcomes of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: the HiSCO-04 prospective cohort study

Author

Mochizuki, Tetsuya, Shimomura, Manabu, Nakahara, Masahiro, Adachi, Tomohiro, Ikeda, Satoshi, Saito, Yasufumi, Shimizu, Yosuke, Kochi, Masatoshi, Ishizaki, Yasuyo, Yoshimitsu, Masanori, Takakura, Yuji, Shimizu, Wataru, Sumitani, Daisuke, Kodama, Shinya, Fujimori, Masahiko, Oheda, Mamoru, Kobayashi, Hironori, Akabane, Shintaro, Yano, Takuya, and Ohdan, Hideki

Published
2024
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5. Predictive factors associated with anastomotic leakage after resection of rectal cancer: a multicenter study with the Hiroshima Surgical study group of Clinical Oncology

Author

Bekki, Tomoaki, Shimomura, Manabu, Adachi, Tomohiro, Miguchi, Masashi, Ikeda, Satoshi, Yoshimitsu, Masanori, Kohyama, Mohei, Nakahara, Masahiro, Kobayashi, Hironori, Toyota, Kazuhiro, Shimizu, Yosuke, Sumitani, Daisuke, Saito, Yasufumi, Takakura, Yuji, Ishizaki, Yasuyo, Kodama, Shinya, Fujimori, Masahiko, Hattori, Minoru, Shimizu, Wataru, and Ohdan, Hideki

Published
2023
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6. A prospective feasibility study of uracil–tegafur and leucovorin as adjuvant chemotherapy for patients aged ≥ 80 years after curative resection of colorectal cancer, the HiSCO-03 study

Author

Okuda, Hiroshi, Shimomura, Manabu, Ikeda, Satoshi, Nakahara, Masahiro, Miguchi, Masashi, Ishizaki, Yasuyo, Saitoh, Yasuhumi, Toyota, Kazuhiro, Sumitani, Daisuke, Shimizu, Yosuke, Takakura, Yuji, Shimizu, Wataru, Yoshimitsu, Masanori, Kodama, Shinya, Fujimori, Masahiko, Oheda, Mamoru, Kobayashi, Hironori, and Ohdan, Hideki

Published
2023
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8. Long-term Survival and Functional Outcomes of Laparoscopic Surgery for Clinical Stage I Ultra-low Rectal Cancers Located Within 5 cm of the Anal Verge: A Prospective Phase II Trial (Ultimate Trial).

Author

Ito, Masaaki, Tsukada, Yuichiro, Watanabe, Jun, Fukunaga, Yosuke, Hirano, Yasumitsu, Sakamoto, Kazuhiro, Hamamoto, Hiroki, Yoshimitsu, Masanori, Horie, Hisanaga, Matsuhashi, Nobuhisa, Kuriu, Yoshiaki, Nagai, Shuntaro, Hamada, Madoka, Yoshioka, Shinichi, Ohnuma, Shinobu, Hayama, Tamuro, Otsuka, Koki, Inoue, Yusuke, Ueda, Kazuki, and Toiyama, Yuji

Abstract

Objective: To clarify the long-term oncological outcomes and postoperative anal, urinary, and sexual functions after laparoscopic surgery for clinical stage I very low rectal carcinoma located near the anal canal. Background: Laparoscopic surgery is widely applied for rectal cancer; however, concerns remain, with some studies showing poorer outcomes compared with open surgery. Methods: This single-arm, phase II trial included patients registered preoperatively from 47 institutions in Japan. The planned sample size was 300. The primary end point was the 3-year local recurrence rate. Anal, urinary, and sexual functions were evaluated using a prospective questionnaire. Results: Three hundred patients were registered between January 2014 and March 2017. Anus-preserving surgery was performed in 278 (93%), including 172 who underwent intersphincteric resection (58%) and 106 (36%) who underwent low anterior resection. The 3-year cumulative local recurrence rate was 6.3%. At 3 years postoperatively, 87% of patients used their own anus, and the median incontinence score improved from 12 at 3 months to 8 at 3 years. Only 5% of patients had severe incontinence (incontinence score of 16 points). Postoperative urinary function evaluation showed that the International Prostate Symptom Score and Overactive Bladder Symptom Score decreased 1 week after surgery but recovered to preoperative level 1 month after surgery. International Consultation on Incontinence Questionnaire-Sort Form remained almost stable after surgery. Sexual function evaluation using the International Index of Erectile Function-5 and International Index of Erectile Function-15 revealed that the patients had deteriorated 3 months after surgery but had recovered only slightly by 6 months. Conclusions: Laparoscopic surgery achieves feasible long-term oncological outcomes and a high rate of anus preservation with moderate anal function and an acceptable incontinence score. While urinary function recovered rapidly, sexual function showed poor recovery. [ABSTRACT FROM AUTHOR]

Published
2025
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11. Preoperative versus Postoperative chemotherapy with CAPOX plus bevacizumab for resectable colorectal liver metastases: A randomised phase II trial (HiSCO-01)

Author

Takakura, Yuji, primary, Shinozaki, Katsunori, additional, Ikeda, Satoshi, additional, Egi, Hiroyuki, additional, Hirata, Yuzo, additional, Shimomura, Manabu, additional, Oshiro, Takafumi, additional, Hinoi, Takao, additional, Sumitani, Daisuke, additional, Nakahara, Masahiro, additional, Yoshimitsu, Masanori, additional, Honmyo, Naruhiko, additional, Fukuda, Saburo, additional, Kobayashi, Tsuyoshi, additional, Tanaka, Junko, additional, and Ohdan, Hideki, additional

Published
2024
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16. Author response to: Comment on: Non-invasive measurement of intestinal tissue oxygen saturation for evaluation of reconstructed blood flow in rectal cancer surgery: HiSCO-09 study

Author

Shimomura, Manabu, primary, Yoshinaka, Hisaaki, additional, Egi, Hiroyuki, additional, Shimizu, Wataru, additional, Adachi, Tomohiro, additional, Ikeda, Satoshi, additional, Nakahara, Masahiro, additional, Saitoh, Yasufumi, additional, Toyota, Kazuhiro, additional, Yoshimitsu, Masanori, additional, Akabane, Shintaro, additional, Yano, Takuya, additional, Hattori, Minoru, additional, and Ohdan, Hideki, additional

Published
2023
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18. Non-invasive measurement of intestinal tissue oxygen saturation for evaluation of reconstructed blood flow in rectal cancer surgery: HiSCO-09 study

Author

Yoshinaka, Hisaaki, primary, Shimomura, Manabu, additional, Egi, Hiroyuki, additional, Shimizu, Wataru, additional, Adachi, Tomohiro, additional, Ikada, Satoshi, additional, Nakahara, Masahiro, additional, Saitoh, Yasufumi, additional, Toyota, Kazuhiro, additional, Yoshimitsu, Masanori, additional, Akabane, Shintaro, additional, Yano, Takuya, additional, Hattori, Minoru, additional, and Ohdan, Hideki, additional

Published
2023
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19. Survival outcomes of patients with stage III colorectal cancer aged ≥80 years who underwent curative resection: The HiSCO-04 prospective cohort study

Author

Mochizuki, Tetsuya, primary, Shimomura, Manabu, additional, Nakahara, Masahiro, additional, Adachi, Tomohiro, additional, Ikeda, Satoshi, additional, Saito, Yasufumi, additional, Shimizu, Yosuke, additional, Kochi, Masatoshi, additional, Ishizaki, Yasuyo, additional, Yoshimitsu, Masanori, additional, Takakura, Yuji, additional, Shimizu, Wataru, additional, Sumitani, Daisuke, additional, Kodama, Shinya, additional, Fujimori, Masahiko, additional, Oheda, Mamoru, additional, Kobayashi, Hironori, additional, Akabane, Shintaro, additional, Yano, Takuya, additional, and Ohdan, Hideki, additional

Published
2023
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22. Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub-analysis of the HiSCO-04 study.

Author

Bekki, Tomoaki, Shimomura, Manabu, Saito, Yasufumi, Nakahara, Masahiro, Adachi, Tomohiro, Ikeda, Satoshi, Shimizu, Yosuke, Kochi, Masatoshi, Ishizaki, Yasuyo, Yoshimitsu, Masanori, Takakura, Yuji, Shimizu, Wataru, Sumitani, Daisuke, Kodama, Shinya, Fujimori, Masahiko, Oheda, Mamoru, Kobayashi, Hironori, Akabane, Shintaro, Yano, Takuya, and Ohdan, Hideki

Subjects
ADJUVANT chemotherapy, OLDER patients, COLORECTAL cancer, SOCIAL background, SOCIAL factors
Abstract

Purpose: Adjuvant chemotherapy is recommended following colorectal cancer resection based on risk of recurrence. In older patients, treatment decisions should consider recurrence rates and tolerability, as well as functional prognosis, residual disease, and social factors. This study aims to investigate factors, including social background, influencing implementation of postoperative adjuvant chemotherapy in older patients undergoing curative resection for colorectal cancer. Methods: This multi-institutional prospective cohort study included 15 institutions belonging to the Hiroshima Surgical study group for Clinical Oncology. We analyzed 159 older patients aged ≥ 80 years, who underwent curative resection for stage III colorectal cancer between December 2013 and June 2018, as sub-analysis of the HiSCO-04 study. Results: In total, 62 (39.0%) patients underwent postoperative adjuvant chemotherapy. Four factors were significantly associated with its implementation: performance status < 2, Charlson Comorbidity Index < 2, prognostic nutritional index ≥ 40, and presence of a spouse or siblings as lifestyle supporters. No significant difference was found in the backgrounds between complete and incomplete postoperative adjuvant chemotherapy patients. Conclusion: Performance status, Charlson Comorbidity Index, nutritional status, and presence of a spouse or siblings as lifestyle supporters are possible factors influencing the implementation of postoperative adjuvant chemotherapy in older patients. To select appropriate treatment options, including postoperative adjuvant chemotherapy, it is essential to consider physical condition and comorbidities of older patients, thoroughly explain the situation to their families, and establish a support system to enhance understanding of the available treatment options. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Prospective cohort study of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: The HiSCO-04 study.

Author

Shimomura, Manabu, primary, Ikeda, Satoshi, additional, Nakahara, Masahiro, additional, Adachi, Tomohiro, additional, Saitoh, Yasufumi, additional, Shimizu, Yosuke, additional, Toyota, Kazuhiro, additional, Ishizaki, Yasuyo, additional, Yoshimitsu, Masanori, additional, Takakura, Yuji, additional, Shimizu, Wataru, additional, Sumitani, Daisuke, additional, Kodama, Shinya, additional, Fujimori, Masahiko, additional, Oeda, Mamoru, additional, Kobayashi, Hironori, additional, and Ohdan, Hideki, additional

Published
2023
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24. Phase 2 multi-institutional prospective feasibility study of uracil-tegafur and leucovorin as adjuvant chemotherapy for patients aged 80 years or more after curative resection of colorectal cancer: The HiSCO-03 study.

Author

Miguchi, Masashi, primary, Ikeda, Satoshi, additional, Shimomura, Manabu, additional, Nakahara, Masahiro, additional, Adachi, Tomohiro, additional, Ishizaki, Yasuyo, additional, Saitoh, Yasufumi, additional, Toyota, Kazuhiro, additional, Sumitani, Daisuke, additional, Shimizu, Yosuke, additional, Takakura, Yuji, additional, Shimizu, Wataru, additional, Yoshimitsu, Masanori, additional, Kodama, Shinya, additional, Fujimori, Masahiko, additional, Oeda, Mamoru, additional, Kobayashi, Hironori, additional, and Ohdan, Hideki, additional

Published
2023
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27. A Case of Foreign Body Granuloma Due to the Presence of a Silk Surgical Thread after Resection of Local Recurrence of Descending Colon Cancer

Author

Matsumoto, Tasuku, primary, Yano, Takuya, additional, Yoshimitsu, Masanori, additional, Ichimura, Kohichi, additional, Nakano, Kanyu, additional, Shirakawa, Yasuhiro, additional, Matsukawa, Hiroyoshi, additional, Idani, Hitoshi, additional, Shiozaki, Shigehiro, additional, and Okajima, Masazumi, additional

Published
2022
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28. Proper use of appendiceal stump closure methods for surgical site infection in laparoscopic appendectomy

Author

Fukuhara, Sotaro, primary, Yano, Takuya, additional, Yoshimitsu, Masanori, additional, Oshita, Ko, additional, Katsura, Yuki, additional, Ishida, Michihiro, additional, Satoh, Daisuke, additional, Choda, Yasuhiro, additional, Nakano, Kanyu, additional, Shirakawa, Yasuhiro, additional, Matsukawa, Hiroyoshi, additional, Idani, Hitoshi, additional, Shiozaki, Shigehiro, additional, and Okajima, Masazumi, additional

Published
2022
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29. Single-incision laparoscopic ileocolectomy for solitary cecal colon diverticulitis with calcified fecalith: a case report

Author

Shimizu, Akito, primary, Yoshimitsu, Masanori, additional, Yano, Takuya, additional, Chogahara, Ichiya, additional, Fukuhara, Sotaro, additional, Nakano, Kanyu, additional, Idani, Hitoshi, additional, Okajima, Masazumi, additional, Ishida, Michihiro, additional, Satoh, Daisuke, additional, Choda, Yasuhiro, additional, Shirakawa, Yasuhiro, additional, Matsukawa, Hiroyoshi, additional, and Shiozaki, Shigehiro, additional

Published
2022
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36. Proper use of appendiceal stump closure methods for surgical site infection in laparoscopic appendectomy.

Author

Fukuhara, Sotaro, Yano, Takuya, Yoshimitsu, Masanori, Oshita, Ko, Katsura, Yuki, Ishida, Michihiro, Satoh, Daisuke, Choda, Yasuhiro, Nakano, Kanyu, Shirakawa, Yasuhiro, Matsukawa, Hiroyoshi, Idani, Hitoshi, Shiozaki, Shigehiro, and Okajima, Masazumi

Subjects
SURGICAL site infections, STAPLERS (Surgery), APPENDECTOMY, PREOPERATIVE risk factors, APPENDIX (Anatomy), SURGICAL complications, PROPENSITY score matching
Abstract

Introduction: Although some studies have reported on the relationship between appendiceal stump closure methods and postoperative complications, there is no fixed method for this procedure. This study aimed to compare treatment outcomes of the existing procedures. Methods: We retrospectively analyzed the records of 200 patients who underwent urgent laparoscopic surgeries and investigated whether the difference in the appendiceal stump closure method was a risk factor for surgical site infection. The patients were divided into the Endoloop and endostapler groups, and 45 propensity score‐matched patients were included. The treatment outcomes of the two groups were compared. Results: The patients with high body temperature showed significantly developed surgical site infection in multivariate analysis (P =.036). There was no significant difference in the appendix stump methods (Endoloop vs endostapler). Regarding postoperative complications, superficial and deep incisional surgical site infection, organ/space surgical site infection, ileus, and complications of Clavien–Dindo grade IIIa or higher; there was no significant difference between the endoloop and endostapler groups after propensity score matching (P =.725, 1.000,.645 and.557, respectively). Conclusion: By properly using the Endoloop and endostapler according to the severity of inflammation, the Endoloop can be safely performed in many cases. Inexpensive Endoloop as an option for stump closure methods should positively impact medical costs. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Rare Contents of an Internal Hernia through a Defect of the Broad Ligament of the Uterus

Author

Takahashi, Masafumi, Yoshimitsu, Masanori, Yano, Takuya, Idani, Hitoshi, Shiozaki, Shigehiro, and Okajima, Masazumi

Subjects
Article Subject
Abstract

Herniation through a defect of the uterine broad ligament is a rare internal hernia that is difficult to diagnose definitively. Common hernia contents contain ileal loops. Herein, we report a rare case of internal herniation of both the ileum and fallopian tube through a defect of the broad ligament. A 52-year-old woman presented to our hospital with suprapubic pain and vomiting. She had a history of bowel obstruction following cesarean section. On abdominopelvic computed tomography, we suspected a closed-loop obstruction associated with bowel herniation in the right broad ligament. However, we could not identify an area of poor enhancement adjacent to distended small intestines. Emergency laparoscopic exploration revealed a viable ileal loop and incarcerated organ. Therefore, we switched to laparotomy that revealed the right fallopian tube as the ischemic organ. We reduced the hernia, resected necrotic right fallopian tube, and closed the defect of the broad ligament. The patient had an uneventful postoperative course. Rare hernia contents might complicate preoperative clinical diagnosis. Laparoscopy is useful for establishing a definitive diagnosis and treating broad ligament hernias.

Published
2021
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45. Adult Intussusception Due to Endometriosis Arising from the Uterine Tube: Report of a Case

Author

Yoshikawa, Toru, Ibuki, Yuta, Kaneko, Mayumi, Teramoto, Hideki, Yoshimitsu, Masanori, Emi, Manabu, Kohashi, Toshihiko, Hihara, Jun, Mukaida, Hidenori, and Hirabayashi, Naoki

Subjects
endometriosis, adult intussusception, laparoscopic surgery
Abstract

Introduction: Endometriosis is a rare cause of intussusceptions in adults. Although intestinal endometriosis sometimes arises as a consequence of direct involvement of the pelvic organs with endometrial tissue, there is no report that this type of endometriosis causes ileocecal intussusception. Case presentation: Computed tomography assessment of a 40-year-old woman who presented with abdominal pain revealed ileocecal intussusceptions. The patient was managed by endoscopic reduction followed by laparoscopic resection. Adhesion between the right uterine adnexa and caecum was identified during surgery; therefore, combined resection of the uterine adnexa and ileocecum was performed. Pathological findings revealed that endometriosis, arising from the uterine tube and directly involving the cecal wall, had caused the intussusceptions. Conclusion: Although rare, endometriosis should be considered as part of a differential diagnosis of intussusception in adult women who present with abdominal pain. A preoperative diagnosis is sometimes difficult, therefore, surgical resection could be a reasonable strategy to achieve a precise diagnosis.

Published
2018

49. Successful Use of Negative Pressure Wound Therapy for Abdominal Wall Necrosis Caused by a Perforated Ascending Colon Using the ABThera System

Author

Imaoka, Kouki, primary, Yano, Takuya, additional, Choda, Yasuhiro, additional, Oshita, Ko, additional, Tani, Yuma, additional, Kubota, Tetsushi, additional, Ishida, Michihiro, additional, Satoh, Daisuke, additional, Yoshimitsu, Masanori, additional, Nakano, Kanyu, additional, Harano, Masao, additional, Matsukawa, Hiroyoshi, additional, Idani, Hitoshi, additional, Shiozaki, Shigehiro, additional, and Okajima, Masazumi, additional

Published
2020
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50. Pre- versus postoperative CAPOX plus bevacizumab (CAPOX-Bev) for resectable liver metastases from colorectal cancer (CLM): A randomized phase II/III trial (HiSCO-01).

Author

Takakura, Yuji, primary, Shinozaki, Katsunori, additional, Ikeda, Satoshi, additional, Egi, Hiroyuki, additional, Hirata, Yuzo, additional, Shimomura, Manabu, additional, Oshiro, Takafumi, additional, Hinoi, Takao, additional, Sumitani, Daisuke, additional, Nakahara, Masahiro, additional, Yoshimitsu, Masanori, additional, Honmyo, Naruhiko, additional, Kobayashi, Tsuyoshi, additional, and Ohdan, Hideki, additional

Published
2020
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