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The number of science projects with citizen (volunteer) participants is increasing nowadays. Despite some advantages citizen science have which directly influence science fields, the largest weakness of citizen science is the issue of the reliability of data collected by non-specialists. In this study, we assess the reliability of data collected by citizens and identify the factors that impede the credibility. We selected two species, Pelophylax chosenicus and Dryophytes suweonensis, which have specific habitat, breeding and brumation positions. The location data for both species were collected by the global citizen engagement project “iNaturalist”. As a result, 89.3% for P. chosenicus and 37.1% for D. suweonensis of the location data were estimated to be erroneous. No difference was observed in the data accuracy between experts and citizens for D. suweonensis because the mating call is the main classification key for the species. On the other hand, a significant difference was confirmed in the case of P. chosenicus, whose external characteristics are its classification key. Our study shows that efforts to improve reliability, including appropriate species selection and survey methods, are necessary to use citizen participation data in science research.

Background/Aims:Tenofovir disoproxil fumarate (TDF) exhibits similar antiviral efficacy against treatment-naïve and lamivudine (LAM)-resistant chronic hepatitis B (CHB). However, there are few clinical reports on the antiviral effects of TDF–LAM combination therapy compared to TDF monotherapy in patients with LAM-resistant CHB. Methods:We investigated the antiviral efficacy of TDF monotherapy vs. TDF–LAM combination therapy in 103 patients with LAM-resistant CHB. Results:The study subjects were treated with TDF alone (n=40) or TDF–LAM combination therapy (n=63) for ≥6 months. The patients had previously been treated with TDF-based rescue therapy for a median of 30.0 months (range, 8–36 months). A virologic response (VR) was achieved in 99 patients (96.1%): 95.0% (38/40) of patients in the TDF monotherapy group and 96.8% (61/63) of patients in the TDF–LAM combination therapy group. The VR rates were not significantly different between the TDF monotherapy and TDF–LAM combination therapy groups (88.9 vs. 87.3% at month 12, and 94.4 vs. 93.7% at month 24, log-rank p=0.652). Univariate and multivariate analyses revealed that none of the pretreatment factors were significantly associated with VR. Conclusions:TDF monotherapy was as effective as TDF–LAM combination therapy for maintaining viral suppression in the vast majority of patients with LAM-resistant CHB, which suggests that TDF add-on therapy with LAM is unnecessary.

Abstract We have investigated exciton localization in binary GaN nanorods using micro- and time-resolved photoluminescence measurements. The temperature dependence of the photoluminescence has been measured, and several phonon replicas have been observed at the lower energy side of the exciton bound to basal stacking faults (I1). By analyzing the Huang-Rhys parameters as a function of temperature, deduced from the phonon replica intensities, we have found that the excitons are strongly localized in the lower energy tails. The lifetimes of the I1 and I2 transitions were measured to be < 100 ps due to enhanced surface recombination. PACS: 78.47.+p, 78.55.-m, 78.55.Cr, 78.66.-w, 78.66.Fd