1. Seroprevalence of antibodies to measles, mumps, and rubella among Thai population: evaluation of measles/MMR immunization programme.
- Author
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Tharmaphornpilas P, Yoocharean P, Rasdjarmrearnsook AO, Theamboonlers A, and Poovorawan Y
- Subjects
- Adolescent, Age Factors, Child, Female, Humans, Male, Measles epidemiology, Measles Vaccine administration & dosage, Measles Vaccine immunology, Measles virus immunology, Mumps epidemiology, Mumps Vaccine administration & dosage, Mumps Vaccine immunology, Mumps virus immunology, Rubella epidemiology, Rubella Vaccine administration & dosage, Rubella Vaccine immunology, Seroepidemiologic Studies, Thailand epidemiology, Time Factors, Vaccines, Combined administration & dosage, Vaccines, Combined immunology, Antibodies, Viral blood, Immunization Programs, Measles-Mumps-Rubella Vaccine administration & dosage, Measles-Mumps-Rubella Vaccine immunology
- Abstract
Stored serum specimens, from four regions of Thailand, of healthy children attending well baby clinics and of healthy people with acute illnesses visiting outpatient clinics were randomly sampled and tested for IgG antibody to measles, mumps, and rubella (MMR). The immunity patterns of rubella and mumps fitted well with the history of rubella and MMR vaccination, seroprotective rates being over 85% among those aged over seven years. A high proportion of younger children acquired the infection before the age of vaccination. MMR vaccination should preferably be given to children at an earlier age. For measles, 73% seroprotective rates among children, aged 8-14 years, who should have received two doses of measles/MMR vaccine, were lower than expected. This finding was consistent with the age-group reported in outbreaks of measles in Thailand. The apparent ineffectiveness (in relation to measles) of MMR immunization of 1st grade students warrants further studies.
- Published
- 2009
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