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1. Profiles and natural drivers of antibiotic resistome in multiple environmental media in penguin-colonized area in Antarctica

Author

Yongpeng Zhang, Bo Zhang, Imtiaz Ahmed, Hanshu Zhang, and Yiliang He

Subjects
Antibiotic resistance genes, Antibiotic-resistant bacteria, Risk, Mobile genetic element, Source, Science (General), Q1-390
Abstract

Profiles and driving mechanisms of antibiotic resistome in the polar region are important for exploring the natural evolution of antibiotic resistance genes (ARGs). Here, we evaluated the profiles of antibiotic resistome in multiple media on Inexpressible Island, Terra Nova Bay, Antarctica. Average concentrations of ARGs in intracellular DNA (iARGs) among water (3.98 × 106 copies/L), soil (3.41 × 107 copies/kg), and penguin guano (7.04 × 107 copies/kg) were higher than those of ARGs in extracellular DNA (eARGs) among water (1.99 × 104 copies/L), soil (1.75 × 106 copies/kg), and penguin guano (8.02 × 106 copies/kg). It was indicated that the transmission of ARGs across different media occurs with around 77.8% of iARGs from soil and 86.7% of iARGs from penguins observed in water, and 80.7% of iARGs and 56.7% of eARGs from penguins found in soil. Annual inputs of ARGs from Adélie penguins on Inexpressible Island have increased since 1983. Bacitracin, multidrug, and aminoglycoside resistance genes were the main ARGs among water, soil, and penguin guano. Primary medium-risk ARGs associated with human pathogenic bacteria were multidrug resistance genes, and main low-risk ARGs associated with mobile genetic elements (MGEs) were aminoglycoside resistance genes. Antibiotic-resistant bacteria (ARB) from soil and penguins were more phylogenetically related to aquatic antibiotic-resistant mesophiles than aquatic antibiotic-resistant psychrophiles. MGEs, ARB, bacterial diversities, antibiotics, and metals could explain total ARGs between water and soil. Intracellular MGEs were the most significant in-situ driver of iARGs in water, reflecting that horizontal gene transfer could facilitate the spread of ARGs in water. Penguins were important ex-situ drivers of environmental antibiotic resistome, which was linked with risky ARGs between water and soil. These findings highlight the major roles of natural drivers (e.g., MGEs and penguins) in shaping environmental antibiotic resistome in polar areas, improving our understanding of the evolution of environmental microbiome.

Published
2025
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2. JUNO sensitivity to invisible decay modes of neutrons

Author

JUNO Collaboration, Angel Abusleme, Thomas Adam, Kai Adamowicz, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Marco Beretta, Antonio Bergnoli, Daniel Bick, Lukas Bieger, Svetlana Biktemerova, Thilo Birkenfeld, Iwan Blake, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Stéphane Callier, Steven Calvez, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Vanessa Cerrone, Jinfan Chang, Yun Chang, Auttakit Chatrabhuti, Chao Chen, Guoming Chen, Pingping Chen, Shaomin Chen, Xin Chen, Yiming Chen, Yixue Chen, Yu Chen, Zelin Chen, Zhangming Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Yu Chin Cheng, Alexander Chepurnov, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Yen-Ting Chin, Po-Lin Chou, Ziliang Chu, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Alberto Coppi, Daniele Corti, Simon Csakli, Chenyang Cui, Flavio Dal Corso, Olivia Dalager, Jaydeep Datta, Christophe De La Taille, Zhi Deng, Ziyan Deng, Xiaoyu Ding, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Carsten Dittrich, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Wei Dou, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Yujie Duan, Katherine Dugas, Stefano Dusini, Hongyue Duyang, Jessica Eck, Timo Enqvist, Andrea Fabbri, Ulrike Fahrendholz, Lei Fan, Jian Fang, Wenxing Fang, Dmitry Fedoseev, Li-Cheng Feng, Qichun Feng, Federico Ferraro, Amélie Fournier, Fritsch Fritsch, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Marco Grassi, Maxim Gromov, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Rosa Maria Guizzetti, Cong Guo, Wanlei Guo, Caren Hagner, Hechong Han, Ran Han, Yang Han, Jinhong He, Miao He, Wei He, Xinhai He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jun Hu, Peng Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Jinhao Huang, Junting Huang, Kaixuan Huang, Shengheng Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Leonard Imbert, Ara Ioannisian, Roberto Isocrate, Arshak Jafar, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Cailian Jiang, Di Jiang, Guangzheng Jiang, Wei Jiang, Xiaoshan Jiang, Xiaozhao Jiang, Yixuan Jiang, Xiaoping Jing, Cécile Jollet, Li Kang, Rebin Karaparabil, Narine Kazarian, Ali Khan, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Sergey Kuleshov, Sindhujha Kumaran, Nikolay Kutovskiy, Loïc Labit, Tobias Lachenmaier, Haojing Lai, Cecilia Landini, Sébastien Leblanc, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Gaosong Li, Hongjian Li, Huang Li, Jiajun Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Shuo Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, An-An Liang, Hao Liang, Jiajun Liao, Yilin Liao, Yuzhong Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Xin Ling, Ivano Lippi, Caimei Liu, Fang Liu, Fengcheng Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hongyang Liu, Jianglai Liu, Jiaxi Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shenghui Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Xuewei Liu, Yankai Liu, Zhen Liu, Lorenzo Loi, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Meishu Lu, Peizhi Lu, Shuxiang Lu, Xianguo Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Fengjiao Luo, Guang Luo, Jianyi Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Marco Malabarba, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anita Meraviglia, Anselmo Meregaglia, Emanuela Meroni, Lino Miramonti, Nikhil Mohan, Michele Montuschi, Cristobal Morales Reveco, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Alexey Nikolaev, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, George Parker, Sergio Parmeggiano, Achilleas Patsias, Yatian Pei, Luca Pelicci, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Elisa Percalli, Willy Perrin, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Xiaohui Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Manhao Qu, Zhenning Qu, Gioacchino Ranucci, Alessandra Re, Abdel Rebii, Mariia Redchuk, Gioele Reina, Bin Ren, Jie Ren, Yuhan Ren, Barbara Ricci, Komkrit Rientong, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Deshan Sandanayake, Anut Sangka, Giuseppe Sava, Utane Sawangwit, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Mariangela Settimo, Junyu Shao, Vladislav Sharov, Hexi Shi, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Apeksha Singhal, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Mikhail Smirnov, Oleg Smirnov, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Michail Strizh, Alexander Studenikin, Aoqi Su, Jun Su, Guangbao Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Akira Takenaka, Xiaohan Tan, Jian Tang, Jingzhe Tang, Qiang Tang, Quan Tang, Xiao Tang, Vidhya Thara Hariharan, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Andrea Triossi, Wladyslaw Trzaska, Yu-Chen Tung, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Carlo Venettacci, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Hanwen Wang, Jian Wang, Jun Wang, Li Wang, Lu Wang, Meng Wang, Mingyuan Wang, Qianchuan Wang, Ruiguang Wang, Sibo Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuyi Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Yuehuan Wei, Liangjian Wen, Jun Weng, Christopher Wiebusch, Rosmarie Wirth, Chengxin Wu, Diru Wu, Qun Wu, Yinhui Wu, Yiyang Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Shishen Xian, Ziqian Xiang, Fei Xiao, Xiang Xiao, Xiaochuan Xie, Yijun Xie, Yuguang Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jiayang Xu, Jilei Xu, Jing Xu, Jinghuan Xu, Meihang Xu, Xunjie Xu, Yin Xu, Yu Xu, Baojun Yan, Qiyu Yan, Taylor Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Fengfan Yang, Jie Yang, Lei Yang, Pengfei Yang, Xiaoyu Yang, Yifan Yang, Yixiang Yang, Zekun Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Guojun Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Baobiao Yue, Noman Zafar, Kirill Zamogilnyi, Vitalii Zavadskyi, Fanrui Zeng, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Hangchang Zhang, Haosen Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Junwei Zhang, Lei Zhang, Peng Zhang, Ping Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Shuihan Zhang, Siyuan Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Yibing Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Jie Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Tianhao Zhao, Hua Zheng, Yangheng Zheng, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Xing Zhou, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We explore the decay of bound neutrons in the JUNO liquid scintillator detector into invisible particles (e.g., $$n\rightarrow 3 \nu $$ n → 3 ν or $$nn \rightarrow 2 \nu $$ n n → 2 ν ), which do not produce an observable signal. The invisible decay includes two decay modes: $$ n \rightarrow { inv} $$ n → inv and $$ nn \rightarrow { inv} $$ n n → inv . The invisible decays of s-shell neutrons in $$^{12}\textrm{C}$$ 12 C will leave a highly excited residual nucleus. Subsequently, some de-excitation modes of the excited residual nuclei can produce a time- and space-correlated triple coincidence signal in the JUNO detector. Based on a full Monte Carlo simulation informed with the latest available data, we estimate all backgrounds, including inverse beta decay events of the reactor antineutrino $${\bar{\nu }}_e$$ ν ¯ e , natural radioactivity, cosmogenic isotopes and neutral current interactions of atmospheric neutrinos. Pulse shape discrimination and multivariate analysis techniques are employed to further suppress backgrounds. With two years of exposure, JUNO is expected to give an order of magnitude improvement compared to the current best limits. After 10 years of data taking, the JUNO expected sensitivities at a 90% confidence level are $$\tau /B( n \rightarrow { inv} ) > 5.0 \times 10^{31} \, \textrm{years}$$ τ / B ( n → inv ) > 5.0 × 10 31 years and $$\tau /B( nn \rightarrow { inv} ) > 1.4 \times 10^{32} \, \textrm{years}$$ τ / B ( n n → inv ) > 1.4 × 10 32 years .

Published
2025
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3. Analysis of the Relationship between Surface Soil Moisture and Precipitation over the Loess Plateau

Author

Huiren LIAO, Qian HUANG, Mengyuan WANG, Rui WANG, Junxia ZHANG, Yongpeng ZHANG, and Kun GUO

Subjects
the loess plateau, surface soil moisture, precipitation, correlation analysis, singular value decomposition （svd）, Meteorology. Climatology, QC851-999
Abstract

Observed soil moisture and precipitation as well as GLDAS and CMFD reanalysis data are used to analyze the spatial and temporal distribution and variation trend in the Loess Plateau region.Regression analysis， Granger causality test and singular value decomposition （SVD） are used to study the relationship between soil moisture and precipitation， and to analyze the temporal scale and spatial range of the influence of initial soil moisture on subsequent precipitation.The results show that the explained variance of the regression analysis of soil moisture and subsequent 1~2 months precipitation on the Loess Plateau is relatively high， with larger values in the summer and fall seasons （July， August， September， and October）.That the correlation between soil moisture and the subsequent 21 days of precipitation in different regions of the Loess Plateau （zones I， II， and III） is more frequent and concentrated than that in the whole region.This indicates that soil moisture on the Loess Plateau is heterogeneous so that a larger lagged precipitation time scale is just suitable for analysis at larger spatial scales.The Granger causality test shows that the initial soil moisture in the fall （October and November） across the Loess Plateau has a significant effect on the precipitation in the following 1 or 2 months， and the soil moisture in August also has a significant effect on the precipitation in October in Area III， which is consistent with the results of the regression analysis.The result of the SVD decomposition shows that from 1979 to 2014， when soils in the central， northern， and eastern parts of the Loess Plateau are wetter in July， the precipitation in the western and northern margins of the plateau is accordingly more in August.A wetter soil in the eastern part of the plateau in September means more precipitation in the western part of the plateau， as well as some parts of the northern and southern parts of the plateau， in October.The significant correlation between soil moisture and precipitation has fewer overlapping regions， suggesting spatial and temporal asymmetry in the influence of soil moisture on precipitation on the Loess Plateau.

Published
2024
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4. Spatial and Temporal Distribution Characteristics of Dust Devils in the Qaidam Basin

Author

Mengyuan WANG, Qian HUANG, Huiren LIAO, Yongpeng ZHANG, and Kun GUO

Subjects
dust devils, thermodynamic criteria, occurrence hours, dust emission, qaidam basin, Meteorology. Climatology, QC851-999
Abstract

Dust aerosols are significant components of atmospheric aerosols， and they play a crucial role in global weather and climate changes through radiative effects and the formation of cloud and precipitation.The impact of dust devils on the worldwide emissions of dust aerosols should not be underestimated.The Qaidam Desert located in the northern part of the Tibetan Plateau is a source of dust devils.To investigate the meteorology conditions that lead to the occurrence of dust devils and to understand their spatial and temporal distribution characteristics in the Qaidam Basin， the thermodynamic criteria of dust devils are examined using the ERA5 reanalysis data from 1991 to 2020.The spatio-temporal distributions of the potential dust devil and dust plumes occurrence （PDDPhours） across the Tibetan Plateau and the estimation of dust emission caused by dust devils and dust plumes in the Qaidam Basin have been carried out based on these criteria.In the analysis of trends from 1991 to 2020， lapse rate （LR）， convective ratio （w*/u*）， and PDDPhours have been examined.The precipitation from the Delingha National Basic Meteorological Station， PM2.5 and PM10 from the Delingha Air Quality Monitoring Station， and ultraviolet aerosol index （UVAI） data derived from the Aura satellite from 2016 to 2020 have been utilized to investigate the contribution of dust devils to PM2.5 and PM10 in summer in the Qaidam Basin.The results show that w*/u* and LR are the primary factors that influence the formation of dust devils.The PDDPhours reveals a diurnal cycle with peaking at 12:00 -16:00 （Beijing Time） under different thermodynamic conditions.Based on the diurnal variation of the cumulative contribution of PDDPhours， the combined w*/u* > 5 and LR > 10 K·m-1 criteria are considered to be the most appropriate for determining the occurrence of dust devils in the Qaidam Basin.On the basis of the PDDPhours criteria， the analysis highlights the significant presence of PDDPhours in the Qaidam Basin and the southwestern part of the Tibetan Plateau in summer.The results also reveal that the larger dust devil emissions occur in summer with the average dust emission of up to 1.28×105 t， which accounts for 69.8% of annual dust emissions.The lapse rate has shown a significant downward trend and the convective ratio has shown an upward trend in the Qaidam Basin， which finally lead to an obvious downward trend of PDDPhours.The observations indicate that the annual variation of UVAI shows a larger magnitude in summer， despite there is more precipitation in Delingha during this season compared to others.It indicates that， in addition to the dust storm， dust devils may attribute to PM2.5 and PM10 in summer.

Published
2024
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5. Environmental radon control in the 700 m underground laboratory at JUNO

Author

Chenyang Cui, Jie Zhao, Gaosong Li, Yongpeng Zhang, Cong Guo, Zhenning Qu, Yifang Wang, Xiaonan Li, Liangjian Wen, Miao He, and Monica Sisti

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The Jiangmen Underground Neutrino Observatory is constructing the world’s largest liquid scintillator detector, with a 20 kt target mass and approximately 700 m of overburden. The total underground space of civil construction is around 300,000 m $$^3$$ 3 , with the main hall comprising about 120,000 m $$^3$$ 3 , making it the largest experimental hall in the world. Maintaining a low radon concentration in the underground air is crucial for both human health and the accuracy of experiments involving rare decay detection, such as neutrino and dark matter experiments. To ensure human health and the integrity of neutrino physics experiments, the nominal radon concentration in the main hall must be kept below 200 Bq/m $$^3$$ 3 with a maximum value below 400 Bq/m $$^3$$ 3 . Introduction of fresh air from above ground can significantly lower radon concentration. A benchmark experiment conducted in the refuge room near the main hall revealed that the radon emanating from underground water is a significant source of radon in the underground air. The total underground ventilation rate is approximately 160,000 m $$^3$$ 3 /h of fresh air with about 30 Bq/m $$^3$$ 3 $$^{222}$$ 222 Rn from the bottom of the vertical tunnel after the installation of powerful fans. Of this, 55,000 m $$^3$$ 3 /h is used for ventilation in the main hall. As a result of these measures, the radon concentration inside the main hall has decreased from 1600 Bq/m $$^3$$ 3 to below 200 Bq/m $$^3$$ 3 under stable working conditions, with exceptions during rare adverse weather events or fan failures. The employed strategies to control radon concentration in the underground air are described in this paper.

Published
2024
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6. Prevalence and associated health and lifestyle factors of myopic maculopathy in northern China: the Kailuan eye study

Author

Haiwei Wang, Jinqiong Zhou, Ya Xing Wang, Qian Wang, Yanni Yan, Xuan Yang, Jingyan Yang, Wenjia Zhou, Zihan Nie, Xuhan Shi, Haixia Ji, Yongpeng Zhang, Xuehui Shi, and Wen-Bin Wei

Subjects
Myopic maculopathy, Risk factors, Myopia, Ophthalmology, RE1-994
Abstract

Abstract Background To evaluate the prevalence and associated health and lifestyle factors of myopic maculopathy (MM) in a northern Chinese industrial city. Methods The cross-sectional Kailuan Eye Study included subjects who participated in the longitudinal Kailuan Study in 2016. Ophthalmologic and general examinations were performed on all the participants. MM was graded based on fundus photographs using the International Photographic Classification and Grading System. The prevalence of MM was evaluated. Univariate and multiple logistic regression were adopted to evaluated risk factors of MM. Results The study included 8330 participants with gradable fundus photographs for MM and ocular biometry data. The prevalence of MM was 1.11% (93/8330; 95% confidence interval [CI] 0.89–1.33%). Diffuse chorioretinal atrophy, patchy chorioretinal atrophy, macular atrophy, and plus lesions were observed in 72 (0.9%), 15 (0.2%), 6 (0.007%), and 32 eyes (0.4%), respectively. MM was more common in eyes with longer axial length (OR 4.517; 95%CI 3.273 to 6.235) and in participants with hypertension (OR 3.460; 95%CI 1.152 to 10.391), and older age (OR 1.084; 95%CI 1.036 to 1.134). Conclusions The MM was present in 1.11% of the northern Chinese individuals 21 years or older and the associate factors include longer axial length, older age, and hypertension.

Published
2023
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7. Mass testing and characterization of 20-inch PMTs for JUNO

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Yu Chin Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Yufeng Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Luca Pelicci, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Eric Theisen, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Baobiao Yue, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Main goal of the JUNO experiment is to determine the neutrino mass ordering using a 20 kt liquid-scintillator detector. Its key feature is an excellent energy resolution of at least 3% at 1 MeV, for which its instruments need to meet a certain quality and thus have to be fully characterized. More than 20,000 20-inch PMTs have been received and assessed by JUNO after a detailed testing program which began in 2017 and elapsed for about four years. Based on this mass characterization and a set of specific requirements, a good quality of all accepted PMTs could be ascertained. This paper presents the performed testing procedure with the designed testing systems as well as the statistical characteristics of all 20-inch PMTs intended to be used in the JUNO experiment, covering more than fifteen performance parameters including the photocathode uniformity. This constitutes the largest sample of 20-inch PMTs ever produced and studied in detail to date, i.e. 15,000 of the newly developed 20-inch MCP-PMTs from Northern Night Vision Technology Co. (NNVT) and 5000 of dynode PMTs from Hamamatsu Photonics K. K.(HPK).

Published
2022
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8. Security challenges and defense approaches for blockchain-based services from a full-stack architecture perspective

Author

Hongsong Chen, Xietian Luo, Lei Shi, Yongrui Cao, and Yongpeng Zhang

Subjects
Security and privacy, Blockchain-based services, Full stack, Architecture perspective, Case and experimental study, Formal verification, Information technology, T58.5-58.64
Abstract

As an advantageous technique and service, the blockchain has shown great development and application prospects. However, its security has also met great challenges, and many security vulnerabilities and attack issues in blockchain-based services have emerged. Recently, security issues of blockchain have attracted extensive attention. However, there is still a lack of blockchain security research from a full-stack architecture perspective, as well as representative quantitative experimental reproduction and analysis. We aim to provide a security architecture to solve security risks in blockchain services from a full-stack architecture perspective. Meanwhile, we propose a formal definition of the full-stack security architecture for blockchain-based services, and we also propose a formal expression of security issues and defense solutions from a full-stack security perspective. We use ConCert to conduct a smart contract formal verification experiment by property-based testing. The security vulnerabilities of blockchain services in the Common Vulnerabilities and Exposures (CVE) and China Nation Vulnerability Database (CNVD) are selected and enumerated. Additionally, three real contract-layer real attack events are reproduced by an experimental approach. Using Alibaba's blockchain services and Identity Mixer in Hyperledger Fabric as a case study, the security problems and defense techniques are analyzed and researched. At last, the future research directions are proposed.

Published
2023
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9. Damping signatures at JUNO, a medium-baseline reactor neutrino oscillation experiment

Author

The JUNO collaboration, Jun Wang, Jiajun Liao, Wei Wang, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We study damping signatures at the Jiangmen Underground Neutrino Observatory (JUNO), a medium-baseline reactor neutrino oscillation experiment. These damping signatures are motivated by various new physics models, including quantum decoherence, ν 3 decay, neutrino absorption, and wave packet decoherence. The phenomenological effects of these models can be characterized by exponential damping factors at the probability level. We assess how well JUNO can constrain these damping parameters and how to disentangle these different damping signatures at JUNO. Compared to current experimental limits, JUNO can significantly improve the limits on τ 3/m 3 in the ν 3 decay model, the width of the neutrino wave packet σ x , and the intrinsic relative dispersion of neutrino momentum σ rel.

Published
2022
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10. Model-independent Approach of the JUNO 8B Solar Neutrino Program

Author

Jie Zhao, Baobiao Yue, Haoqi Lu, Yufeng Li, Jiajie Ling, Zeyuan Yu, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Alexander Chepurnov, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Maxim Gromov, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Alexey Nikolaev, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Solar neutrinos, Astrophysics, QB460-466
Abstract

The physics potential of detecting ^8 B solar neutrinos will be exploited at the Jiangmen Underground Neutrino Observatory (JUNO), in a model-independent manner by using three distinct channels of the charged current (CC), neutral current (NC), and elastic scattering (ES) interactions. Due to the largest-ever mass of ^13 C nuclei in the liquid scintillator detectors and the expected low background level, ^8 B solar neutrinos are observable in the CC and NC interactions on ^13 C for the first time. By virtue of optimized event selections and muon veto strategies, backgrounds from the accidental coincidence, muon-induced isotopes, and external backgrounds can be greatly suppressed. Excellent signal-to-background ratios can be achieved in the CC, NC, and ES channels to guarantee the observation of the ^8 B solar neutrinos. From the sensitivity studies performed in this work, we show that JUNO, with 10 yr of data, can reach the 1 σ precision levels of 5%, 8%, and 20% for the ^8 B neutrino flux, ${\sin }^{2}{\theta }_{12}$ , and ${\rm{\Delta }}{m}_{21}^{2}$ , respectively. Probing the details of both solar physics and neutrino physics would be unique and helpful. In addition, when combined with the Sudbury Neutrino Observatory measurement, the world's best precision of 3% is expected for the measurement of the ^8 B neutrino flux.

Published
2024
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11. Study and Quantitative Analysis of Mode Localization in Wind Turbine Blades

Author

Tao Jiang, Xin Guo, Yongpeng Zhang, and Dongsheng Li

Subjects
wind turbine blade, mode localization, detuning, mode localization factor, degree of mode density, mode assurance criterion, Naval architecture. Shipbuilding. Marine engineering, VM1-989, Oceanography, GC1-1581
Abstract

The study of damage mechanisms for wind turbine blades is important. Generally, modal localization tends to accelerate structural damage. This is a new approach to studying these damage mechanisms for wind turbine blades through modal localization theory. Therefore, this paper investigates whether modal localization phenomena exist in wind turbine blades, as well as the impact of different forms of detuning on modal localization. Based on perturbation theory, a mechanism for mode localization is described quantitatively using the degree of detuning, the degree of mode density, and the mode assurance criterion. A finite element model for wind turbine blades was established using ANSYS software (R15.0), and three detuning cases were simulated by changing the density, elastic modulus, and installation angles of the blades. Moreover, an improved mode localization factor is proposed to quantitatively evaluate the degree of mode localization in wind turbine blades. The numerical results indicate that the degree of modal localization increases with an increasing degree of detuning, but the increase in modal localization gradually slows. Finally, the detuning modal shape composition, which includes harmonic components, is analyzed. The results show that the closer the composition of the detuning modes is, the stronger the degree of mode localization.

Published
2023
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12. Herpetic uveitis caused by herpes simplex virus after cataract surgery in a patient without prior viral keratitis or uveitis: a case report

Author

Feng Hu, Wenxue Guan, Yongpeng Zhang, and Xiaoyan Peng

Subjects
Herpetic uveitis, Anterior uveitis, Intraocular surgery, Ocular hypertension, Phacoemulsification surgery, Herpes simplex virus, Ophthalmology, RE1-994
Abstract

Abstract Background To report a case of herpetic uveitis caused by herpes simplex virus after cataract surgery in a patient without prior viral keratitis or uveitis. Case presentation A 70-year-old female was referred to our clinic with a 16-day history of acute blurry vision with painful redness in the right eye. She accepted cataract surgery for the right eye ten days before initial of ocular symptoms. There was significant inflammation in anterior chamber of the right eye. Retina exam showed moderate dense vitreous opacity but not necrotic or focal retinal lesion in the right eye. The aqueous humor collected from the right eye was positive for herpes simplex virus (HSV) DNA by PCR. The diagnosis of herpetic uveitis in the right eye was made due to clinical presentations and aqueous humor examination. Conclusion Herpetic virus reactivation might occasionally occur after intraocular surgery in patients without prior ocular viral diseases, inducing atypical postoperative intraocular inflammation.

Published
2022
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13. The design and sensitivity of JUNO’s scintillator radiopurity pre-detector OSIRIS

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, MinhThuan NguyenThi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangpu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The OSIRIS detector is a subsystem of the liquid scintillator filling chain of the JUNO reactor neutrino experiment. Its purpose is to validate the radiopurity of the scintillator to assure that all components of the JUNO scintillator system work to specifications and only neutrino-grade scintillator is filled into the JUNO Central Detector. The aspired sensitivity level of $$10^{-16}\hbox { g/g}$$ 10 - 16 g/g of $$^{238}\hbox {U}$$ 238 U and $$^{232}\hbox {Th}$$ 232 Th requires a large ( $$\sim 20\,\hbox {m}^3$$ ∼ 20 m 3 ) detection volume and ultralow background levels. The present paper reports on the design and major components of the OSIRIS detector, the detector simulation as well as the measuring strategies foreseen and the sensitivity levels to U/Th that can be reached in this setup.

Published
2021
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14. Radioactivity control strategy for the JUNO detector

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Oliviero Cremonesi, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract JUNO is a massive liquid scintillator detector with a primary scientific goal of determining the neutrino mass ordering by studying the oscillated anti-neutrino flux coming from two nuclear power plants at 53 km distance. The expected signal anti-neutrino interaction rate is only 60 counts per day (cpd), therefore a careful control of the background sources due to radioactivity is critical. In particular, natural radioactivity present in all materials and in the environment represents a serious issue that could impair the sensitivity of the experiment if appropriate countermeasures were not foreseen. In this paper we discuss the background reduction strategies undertaken by the JUNO collaboration to reduce at minimum the impact of natural radioactivity. We describe our efforts for an optimized experimental design, a careful material screening and accurate detector production handling, and a constant control of the expected results through a meticulous Monte Carlo simulation program. We show that all these actions should allow us to keep the background count rate safely below the target value of 10 Hz (i.e. ∼1 cpd accidental background) in the default fiducial volume, above an energy threshold of 0.7 MeV.

Published
2021
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15. JUNO sensitivity to low energy atmospheric neutrino spectra

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and The JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Atmospheric neutrinos are one of the most relevant natural neutrino sources that can be exploited to infer properties about cosmic rays and neutrino oscillations. The Jiangmen Underground Neutrino Observatory (JUNO) experiment, a 20 kton liquid scintillator detector with excellent energy resolution is currently under construction in China. JUNO will be able to detect several atmospheric neutrinos per day given the large volume. A study on the JUNO detection and reconstruction capabilities of atmospheric $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ fluxes is presented in this paper. In this study, a sample of atmospheric neutrino Monte Carlo events has been generated, starting from theoretical models, and then processed by the detector simulation. The excellent timing resolution of the 3” PMT light detection system of JUNO detector and the much higher light yield for scintillation over Cherenkov allow to measure the time structure of the scintillation light with very high precision. Since $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ interactions produce a slightly different light pattern, the different time evolution of light allows to discriminate the flavor of primary neutrinos. A probabilistic unfolding method has been used, in order to infer the primary neutrino energy spectrum from the detector experimental observables. The simulated spectrum has been reconstructed between 100 MeV and 10 GeV, showing a great potential of the detector in the atmospheric low energy region.

Published
2021
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16. Calibration strategy of the JUNO experiment

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Shenjian Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Anna Chuvashova, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Georgy Donchenko, Jianmeng Dong, Damien Dornic, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Marco Fargetta, Anna Fatkina, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Alexandre Göttel, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Franco Giuliani, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Amir Khan, Waseem Khan, Khanchai Khosonthongkee, Patrick Kinz, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Svetlana Krokhaleva, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Jin Li, Kaijie Li, Mengzhao Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Shuaijie Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hu Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Yan Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Axel Müller, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Nikolay Morozov, Waqas Muhammad, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Teerapat Payupol, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Luis Felipe Piñeres Rico, Oliver Pilarczyk, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Dmitry Selivanov, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Jingyan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondrej Sramek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Stefan van Waasen, Johannes van den Boom, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cristina Volpe, Vit Vorobel, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Mengjiao Xiao, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination.

Published
2021
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17. Ocular Adverse Events after Inactivated COVID-19 Vaccination

Author

Zhihua Li, Feng Hu, Qian Li, Shuang Wang, Chunli Chen, Yongpeng Zhang, Yu Mao, Xuehui Shi, Haiying Zhou, Xusheng Cao, and Xiaoyan Peng

Subjects
COVID-19, inactivated vaccine, adverse event, ocular disorder, uveitis, retinal vascular occlusion, Medicine
Abstract

Purpose: To report the clinical characteristics of ocular adverse events that have occurred, in China, after vaccination with inactivated COVID-19 vaccines. Methods: A retrospective cross-sectional observational study was conducted of ocular disorders that occurred within 15 days from any dose of an inactivated COVID-19 vaccine. Information on gender, age, the interval between the vaccination and ocular symptoms, laterality, duration of the ocular symptoms, primary visual acuity, and clinical diagnosis were retrospectively collected. Results: Twenty-four patients were involved in the study, including 15 females and 9 males, with a mean age of 41 ± 16 years (range of 8–71 years). The patients all denied a prior history of COVID-19 infection. Ocular adverse events occurred after the first dose of vaccine in 18 patients and, after the second or third doses, in six patients. The interval between vaccination with the inactivated COVID-19 vaccine and ocular symptoms was 6 ± 5 days; six patients were bilaterally involved and 18 patients were unilaterally involved. Regarding the diagnosis, 10 patients were diagnosed with white dot syndrome (WDS), 9 patients were diagnosed with uveitis, and 5 patients were diagnosed with retinal vascular disorders. The ages of patients with WDS were younger than those with uveitis or retinal vascular disorders (32 ± 10 vs. 48 ± 18, p < 0.05). For patients diagnosed with WDS, the best-corrected visual acuity (BCVA) was 0.74 ± 0.73 LogMAR. For patients diagnosed with retinal vascular disorders or uveitis, the BCVA was 1.44 ± 1.26 LogMAR. There was no significant difference (p > 0.05). Conclusions: A relationship cannot be established between inactivated COVID-19 vaccines and ocular disorders; therefore, further investigation of the clinical spectrum of ocular adverse events after vaccination with an inactivated COVID-19 vaccine is necessary.

Published
2022
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18. Development of Synthetic DNA Circuit and Networks for Molecular Information Processing

Author

Yongpeng Zhang, Yuhua Feng, Yuan Liang, Jing Yang, and Cheng Zhang

Subjects
synthetic DNA circuit, DNA strand displacement, DNA self-assembly, DNA networks, DNA computing, Chemistry, QD1-999
Abstract

Deoxyribonucleic acid (DNA), a genetic material, encodes all living information and living characteristics, e.g., in cell, DNA signaling circuits control the transcription activities of specific genes. In recent years, various DNA circuits have been developed to implement a wide range of signaling and for regulating gene network functions. In particular, a synthetic DNA circuit, with a programmable design and easy construction, has become a crucial method through which to simulate and regulate DNA signaling networks. Importantly, the construction of a hierarchical DNA circuit provides a useful tool for regulating gene networks and for processing molecular information. Moreover, via their robust and modular properties, DNA circuits can amplify weak signals and establish programmable cascade systems, which are particularly suitable for the applications of biosensing and detecting. Furthermore, a biological enzyme can also be used to provide diverse circuit regulation elements. Currently, studies regarding the mechanisms and applications of synthetic DNA circuit are important for the establishment of more advanced artificial gene regulation systems and intelligent molecular sensing tools. We therefore summarize recent relevant research progress, contributing to the development of nanotechnology-based synthetic DNA circuits. By summarizing the current highlights and the development of synthetic DNA circuits, this paper provides additional insights for future DNA circuit development and provides a foundation for the construction of more advanced DNA circuits.

Published
2021
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19. An Entropic Approach to Estimating the Instability Criterion of People in Floodwaters

Author

Zhongfan Zhu, Yongpeng Zhang, Lufeng Gou, and Bo Pang

Subjects
flooding, people, instability, criterion, entropy, Science, Astrophysics, QB460-466, Physics, QC1-999
Abstract

People are always susceptible to a loss of stability in urban floodwaters that leads to serious casualties. Thus, the safety criterion for the instability of people in floodwaters must be determined. In this study, the hydrodynamic criterion of the instability of people in floodwaters in terms of the incipient velocity and water depth is derived using the probability method based on Shannon entropy theory. The derived model can characterize variations in the incipient velocity of people in floodwaters with respect to the inundating water depth. Furthermore, a comparison with seven experimental datasets available in the literature shows the validity of the proposed entropy-based model considering data scattering. A sensitivity analysis of the derived model to some of the incorporated parameters was performed, and the qualitative results are in accordance with our understanding of the physical mechanism of the instability of people in floodwaters. Taking the physical parameters (height and mass) of Chinese adults and children as a representative example, this study also showed the vulnerability degree of Chinese adults and children subject to floodwaters. These findings could provide a reference for administrators and stakeholders for flood hazard mitigation and flood strategy management. This study shows that an entropy-based method could be a valuable addition to existing deterministic models for characterizing the instability criterion of people in an urban flooding event.

Published
2021
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24. Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer

Author

Yingying Yang, Qingmei Zheng, Xinmei Wang, Shuyong Zhao, Wenshu Huang, Linchao Jia, Cuicui Ma, Shicong Liu, Yongpeng Zhang, Qianqian Xin, Yan Sun, and Shansong Zheng

Subjects
Pharmacology, Oncology, Pharmacology (medical)
Abstract

Despite remarkable initial responses of anaplastic lymphoma kinase (ALK) inhibitors in ALK-positive non-small cell lung cancer (NSCLC) patients, cancers eventually develop resistance within one to two years. This study aimed to compare the properties of iruplinalkib (WX‑0593) with other ALK inhibitors and report the comprehensive characterization of iruplinalkib against the crizotinib resistance. The inhibitory effect of iruplinalkib on kinase activity was detected. A kinase screen was performed to evaluate the selectivity of iruplinalkib. The effect of iruplinalkib on related signal transduction pathways of ALK and c-ros oncogene 1 (ROS1) kinases was examined. The cellular and in vivo activities of ALK inhibitors were compared in engineered cancer-derived cell lines and in mice xenograft models, respectively. Human hepatocytes derived from three donors were used for evaluating hepatic enzyme inducing activity. HEK293 cell lines expressing transportors were used to invesigated the drug interaction potential mediated by several transporters. The results showed iruplinalkib potently inhibited the tyrosine autophosphorylation of wild-type ALK, ALKL1196M, ALKC1156Y and epidermal growth factor receptor (EGFR)L858R/T790M. The inhibitory effects of iruplinalkib in patient-derived xenograft and cell line-derived xenograft models were observed. Moreover, iruplinalkib showed robust antitumor effects in BALB/c nude mice xenograft models with ALK-/ROS1-positive tumors implanted subcutaneously, and the tumor suppressive effects in crizotinib-resistant model was significantly better than that of brigatinib. Iruplinalkib did not induce CYP1A2, CYP2B6 and CYP3A4 at therapeutic concentration, and was also a strong inhibitor of MATE1 and MATE2K transporters, as well as P-gp and BCRP. In conclusion, iruplinalkib, a highly active and selective ALK/ROS1 inhibitor, exhibited strong antitumor effects in vitro and in crizotinib-resistant models.

Published
2023
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31. Tropopause folds over the Tibetan Plateau and their impact on water vapor in the upper troposphere-lower stratosphere

Author

Yongpeng Zhang, Qian Huang, Kun Guo, Mengyuan Wang, Huiren Liao, Yan Chou, and Xin He

Abstract

As one of the most important greenhouse gases, water vapor in the upper troposphere and lower stratosphere (UTLS) has a significant impact on the global earth-atmosphere system. The Tibetan Plateau (TP) is an important high terrain which exerts a profound impact on the change of weather and climate, and mass exchange. Tropopause folds occur frequently over the TP due to the impact of the subtropical westerly jet, which affects water vapor transport between the stratosphere and the troposphere. In this paper, the spatial and temporal distribution characteristics of tropopause folds over the TP are examined by applying an improved three-dimensional (3D) labeling algorithm to the ERA5 reanalysis data (1979 to 2019). The effects of different fold depths in various regions over the TP on the variations of UTLS water vapor are further studied. The results of a case study (25 February 2008) suggest that there is a good continuity in identification of the fold depth for the same fold event using the improved 3D labeling algorithm. The fold depth and height are consistent with the results of radiosonde data and ERA5 reanalysis data. The fold frequency over the TP shows an increasing trend in the last 41 years, with slightly lower frequency of medium folds than that of shallow folds, and lowest frequency of deep folds. There is increasing water vapor in the UTLS over the TP due to tropopause folds. The results indicate that tropopause folds enhance the horizontal divergence of water vapor in the UTLS and increase the vertical water vapor flux in the UTLS region. The folding over the plateau leads to increased moisture in the UTLS. It is argued that vertical velocity anomalies in the vicinity of the fold and subgrid perturbations have a significant impact on the increase of UTLS water vapor over the TP. The results of this work provide a scientific basis for a better understanding of the stratosphere-troposphere exchanges due to tropopause folds over the TP.

Published
2023
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35. Security issues and defensive approaches in deep learning frameworks

Author

Hongsong Chen, Yongpeng Zhang, Jing Xie, and Yongrui Cao

Subjects
Multidisciplinary, Computer science, business.industry, Deep learning, Artificial intelligence, business, Data science
Abstract

Deep learning frameworks promote the development of artificial intelligence and demonstrate considerable potential in numerous applications. However, the security issues of deep learning frameworks are among the main risks preventing the wide application of it. Attacks on deep learning frameworks by malicious internal or external attackers would exert substantial effects on society and life. We start with a description of the framework of deep learning algorithms and a detailed analysis of attacks and vulnerabilities in them. We propose a highly comprehensive classification approach for security issues and defensive approaches in deep learning frameworks and connect different attacks to corresponding defensive approaches. Moreover, we analyze a case of the physical-world use of deep learning security issues. In addition, we discuss future directions and open issues in deep learning frameworks. We hope that our research will inspire future developments and draw attention from academic and industrial domains to the security of deep learning frameworks.

Published
2021
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49. Automated detection of severe diabetic retinopathy using deep learning method

Author

Yongpeng Zhang, Huan Chen, Bojie Hu, Qijie Wei, Xirong Li, Bilei Zhang, Xiao Zhang, Bin Mo, Weihong Yu, Fan li, Dayong Ding, Donghong Li, Youxin Chen, and Xiaoxu Han

Subjects
Fundus Oculi, Computer science, Harmonic mean, Fundus (eye), Cellular and Molecular Neuroscience, Deep Learning, Artificial Intelligence, Diabetes Mellitus, Photography, medicine, Intraretinal microvascular abnormalities, Humans, Diabetic Retinopathy, Pixel, business.industry, Pattern recognition, Diabetic retinopathy, medicine.disease, Sensory Systems, Cotton wool spots, Ophthalmology, Test set, Vitreous hemorrhage, Artificial intelligence, medicine.symptom, business, Algorithms
Abstract

The purpose of this study is to develop and validate the intelligent diagnosis of severe DR with lesion recognition based on color fundus photography. The Kaggle public dataset for DR grading is used in the project, including 53,576 fundus photos in the test set, 28,101 in the training set, and 7,025 in the validation set. We randomly select 4,192 images for lesion annotation. Inception V3 structure is adopted as the classification algorithm. Both 299 × 299 pixel images and 896 × 896 pixel images are used as the input size. ROC curve, AUC, sensitivity, specificity, and their harmonic mean are used to evaluate the performance of the models. The harmonic mean and AUC of the model of 896 × 896 input are higher than those of the 299 × 299 input model. The sensitivity, specificity, harmonic mean, and AUC of the method with 896 × 896 resolution images as input for severe DR are 0.925, 0.907, 0.916, and 0.968, respectively. The prediction error mainly occurs in moderate NPDR, and cases with more hard exudates and cotton wool spots are easily predicted as severe cases. Cases with preretinal hemorrhage and vitreous hemorrhage are easily identified as severe cases, and IRMA is the most difficult lesion to recognize. We have studied the intelligent diagnosis of severe DR based on color fundus photography. This artificial intelligence–based technology offers a possibility to increase the accessibility and efficiency of severe DR screening.

Published
2021
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