Search

Your search keyword '"Ying-Sha Yang"' showing total 1 results
Start Over Author "Ying-Sha Yang"
1 results on '"Ying-Sha Yang"'

1. Synthesis of difluoromethylated 2-oxindoles and quinoline-2,4-diones via visible light-induced tandem radical cyclization of N-arylacrylamides

Author

Wen-Xuan Wang, Lin Li, Ji-Kai Liu, Zheng-Hui Li, Yun-Yun Li, Huan Sun, Yue Jiang, Ying-Sha Yang, and Tao Feng

Subjects
Quenching (fluorescence), Tandem, 010405 organic chemistry, Chemistry, Organic Chemistry, Quinoline, 010402 general chemistry, 01 natural sciences, Biochemistry, Radical cyclization, Combinatorial chemistry, 0104 chemical sciences, chemistry.chemical_compound, Photocatalysis, Physical and Theoretical Chemistry, Visible spectrum
Abstract

Visible light-induced difluoromethylation of N-arylacrylamides to afford difluoromethylated 2-oxindoles and quinoline-2,4-diones with difluoromethyl 2-pyridyl sulfones as radical precursors has been disclosed. This method provides convenient access to a variety of 2-oxindoles and quinoline-2,4-diones under mild conditions via a proposed tandem radical addition/cyclization process along with good tolerance to various functional groups. In addition, preliminary experimental studies have revealed that water is a key factor in difluoromethylation and the reaction involves an oxidative quenching cycle of the photocatalyst.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results