Search

Your search keyword '"Ying, Xiaozhou"' showing total 38 results
Start Over Author "Ying, Xiaozhou"
38 results on '"Ying, Xiaozhou"'

21. Ligustilide alleviated IL-1β induced apoptosis and extracellular matrix degradation of nucleus pulposus cells and attenuates intervertebral disc degeneration in vivo

Author

Wang, Ke, primary, Chen, Tingting, additional, Ying, Xiaozhou, additional, Zhang, Zengjie, additional, Shao, Zhenxuan, additional, Lin, Jialiang, additional, Xu, Tianzhen, additional, Chen, Yu, additional, Wang, Xiangyang, additional, Chen, Jiaoxiang, additional, and Sheng, Sunren, additional

Published
2019
Full Text
View/download PDF

24. Comparison of percutaneous cannulated screw fixation and calcium sulfate cement grafting versus minimally invasive sinus tarsi approach and plate fixation for displaced intra-articular calcaneal fractures: a prospective randomized controlled trial

Author

Feng, Yongzeng, primary, Shui, Xiaolong, additional, Wang, Jianshun, additional, Cai, Leyi, additional, Yu, Yang, additional, Ying, Xiaozhou, additional, Kong, Jianzhong, additional, and Hong, Jianjun, additional

Published
2016
Full Text
View/download PDF

34. Comparison of percutaneous cannulated screw fixation and calcium sulfate cement grafting versus minimally invasive sinus tarsi approach and plate fixation for displaced intra-articular calcaneal fractures: a prospective randomized controlled trial.

Author

Yongzeng Feng, Xiaolong Shui, Jianshun Wang, Leyi Cai, Yang Yu, Xiaozhou Ying, Jianzhong Kong, Jianjun Hong, Feng, Yongzeng, Shui, Xiaolong, Wang, Jianshun, Cai, Leyi, Yu, Yang, Ying, Xiaozhou, Kong, Jianzhong, and Hong, Jianjun

Subjects
HEEL bone fractures, INTERNAL fixation in fractures, FRACTURE fixation, CALCIUM sulfate, BONE cements, THERAPEUTICS, HEEL bone injuries, CALCIUM compounds, SUBTALAR joint, BONE screws, COMPARATIVE studies, COMPUTED tomography, BONE fractures, MINIMALLY invasive procedures, HEEL bone, RANGE of motion of joints, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, ORTHOPEDIC implants, RADIOGRAPHY, RESEARCH, SURGICAL complications, EVALUATION research, RANDOMIZED controlled trials, TREATMENT effectiveness, HEEL (Anatomy), PHYSIOLOGY, SURGERY, EQUIPMENT & supplies
Abstract

Background: The management of displaced intra-articular calcaneal fractures (DIACFs) remains challenging and controversial. A prospective randomized controlled trial was conducted to compare percutaneous reduction, cannulated screw fixation and calcium sulfate cement (PR+CSC) grafting with minimally invasive sinus tarsi approach and plate fixation (MISTA) for treatment of DIACFs.Methods: Ultimately, 80 patients with a DIACFs were randomly allocated to receive either PR+CSC (N = 42) or MISTA (N = 38). Functional outcomes were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot scores. Radiological results were assessed using plain radiographs and computed tomography (CT) scans, and postoperative wound-related complications were also recorded.Results: The average time from initial injury to operation and the average operation time in the PR+CSC group were both significantly shorter than those in the MISTA group (p < 0.05). There were significantly fewer complications in the PR+CSC group than those in the MISTA group (7.1 % vs 28.9 %, p < 0.001). The calcaneal width immediate postoperatively and at the final follow-up in the MISTA group were obviously improved compared to those in the PR+CSC group (p < 0.001). The variables of sagittal motion and hindfoot motion of the AOFAS scoring system in the PR+CSC group were significantly higher than those in the MISTA group (p < 0.05). The good and excellent results in the two groups were comparable for Sanders Type-II calcaneal fractures, but the good to excellent rate in the MISTA group was significantly higher for Sanders Type-III fractures (p < 0.05).Conclusion: The clinical outcomes are comparable between the two minimally invasive techniques in the treatment of Sanders Type-II DIACFs. The PR+CSC grafting is superior to the MISTA in terms of the average time between initial injury and operation, operation time, wound-related complications and subtalar joint activity. However, the MISTA has its own advantages in improving the calcaneal width, providing a more clear visualization and accurate reduction of the articular surface, especially for Sanders Type-III DIACFs.Trial Registration: ChiCTRIOR16008512 . 21 May 2016. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

35. Nicotine promotes proliferation and collagen synthesis of chondrocytes isolated from normal human and osteoarthritis patients

Author

Ying, Xiaozhou, primary, Cheng, Shaowen, additional, Shen, Yue, additional, Cheng, Xiaojie, additional, An Rompis, Ferdinand, additional, Wang, Wei, additional, Lin, Zhongqin, additional, Chen, Qingyu, additional, Zhang, Wei, additional, Kou, Dongquan, additional, Peng, Lei, additional, Tian, Xin Qiao, additional, and Lu, Chuan Zhu, additional

Published
2011
Full Text
View/download PDF

37. Phosphoserine promotes osteogenic differentiation of human adipose stromal cells through bone morphogenetic protein signalling.

Author

Ying, Xiaozhou, Chen, Xiaowei, Cheng, Shaowen, Guo, Xiaoshan, Chen, Hua, and Xu, Hua zi

Subjects
*PHOSPHOSERINE, *BONE growth, *CELL differentiation, *STROMAL cells, *BONE morphogenetic proteins, *CELLULAR signal transduction, *ALKALINE phosphatase
Abstract

Phosphoserine has potential effectiveness as a simple substrate in preparing bone replacement materials, which could enhance bone forming ability. However, there is a need to investigate the independent effect of phosphoserine on osteogenic differentiation of human adipose stem cells (hADSCs). hADSCs were cultured in an osteogenic medium with phosphoserine. Cell proliferation was analysed by CCK8 and osteogenic differentiation was measured by alkaline phosphatase (ALP) activity, von Kossa staining and real time-polymerase chain reaction (RT-PCR). No stimulatory effect of phosphoserine on cell proliferation was noted at Days 1, 4 and 7. Deposition of calcium increased after the addition of phosphoserine. mRNA expression of type I collagen (COL-I), alkaline phosphatase (ALP), osteocalcin (OCN), Osterix, bone morphogenetic protein-2 (BMP-2) and RUNX2 increased markedly with phosphoserine treatment. The BMP-2 antagonist, noggin, and its receptor kinase inhibitors, dorsomorphin and LDN-193189, attenuated phosphoserine-promoted ALP activity. BMP-responsive and Runx2-responsive reporters were activated by phosphoserine treatment. Thus phosphoserine can promote osteogenic differentiation of hADSCs, probably by activating BMP and Runx2 pathways, which could be a promising approach for enhancing osteogenic capacity of cell-based construction in bone tissue engineering. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results