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Salmonella osteomyelitis is an underdiagnosed pathology with unusual clinical presentations. The patient was a 24-year-old female with no previous medical history who presented to the emergency department with progressive pain in the left arm for several months. She was initially treated unsuccessful with augmentin for 7 days for suspicious cellulites. Standard elbow X-rays described a lesion initially considered as metastatic. Investigations were completed with magnetic resonance imaging (MRI) compatible with osteomyelitis. Following surgical sampling, salmonella enterica infection was diagnosed. The patient recovered full use of her limb after 8 days of IV antibiotic therapy with third-generation cephalosporin, and she completed 11 weeks of antibiogram-targeted PO fluoroquinolone therapy. Salmonella osteomyelitis could mimic other diseases, making diagnosis difficult.

Pulmonary arteriovenous malformations (PAVMs) are abnormal communications between the arteries and veins of the pulmonary vasculature leading to a right-to-left shunt. We report the case of a pregnant patient who presented with chest pain revealing a haemothorax secondary to the rupture of an arteriovenous malformation. The diagnosis was made during arteriography after simultaneous performance of an urgent caesarean section and thoracic drainage.

Vertebro-basilar dolichoectasia (VBD) is a rare pathology of unknown aetiology. Its clinical presentation is wide and prognosis is generally poor with a high mortality rate. Cerebral magnetic resonance imaging is the gold standard for diagnosis. We report an unusual case of intracranial dolichoectasia. VBD was revealed during investigation of a patient with altered mental status. CT brain imaging demonstrated severe obstructive hydrocephalus secondary to compression of the third ventricle. Management is always challenging and depends on the location and the mode of presentation. Our patient died despite surgical management with placement of an external ventricular shunt

İnovasyon ve Ar-Ge, ülkelerin gelişmişlik düzeylerinin ve ekonomisinin değer kazanması açısından büyük önem taşımaktadır. Türkiye’de teknoloji geliştirme bölgelerinde Ar-Ge ekosisteminin gelişimi hızla artarak devam etmektedir. Çalışmamız genel olarak Ar-Ge ve inovasyonun dünyadaki ve Türkiye’deki durumuna gelişim süreçlerine, mevcut konumuna yer vermiştir. Çalışmanın uygulama kısmında Dokuz Eylül Teknoloji Geliştirme bölgesinde faaliyet göstermekte olan yazılım sektöründeki işletmeler içinde açık inovasyonun etkisine yönelik bir uygulama gerçekleştirilmiştir. Klasik istatistik yöntemlerinin yanı sıra veri madenciliği algoritmalarından Apriori algoritması ve birliktelik kuralları çerçevesinde analiz edilmiştir.

We report the case of an 86-year-old female patient with chronic neck pain who presented with an initial misleading clinical picture suggesting an ischaemic stroke. No recent or previous anticoagulation treatment or fall history was reported. The patient developed a paraplegia of the upper limbs needing magnetic resonance imaging which revealed a compressive cervical haematoma. The patient benefitted from cervical laminectomy and evacuation of the cervical haematoma. Motricity in upper extremities was recovered but paresis in the lower extremities persisted 1 week after surgical intervention.

Acute gastric volvulus is a rare complication affecting 4% of hiatal hernias. It is described as an abnormal rotation of the stomach around a transverse or longitudinal axis and can be intra-abdominal or intrathoracic. Intrathoracic gastric volvulus can lead to tension gastrothorax, which is defined as the presence of a massive gastric distension in the chest cavity causing a mediastinal shift with haemodynamic instability and a risk of cardiorespiratory arrest. We report a case of intrathoracic gastric volvulus with probable tension gastrothorax. Early diagnosis of gastrothorax with computed tomography and immediate insertion of a nasogastric tube resulted in rapid clinical improvement. Surgical intervention is the treatment of choice.

Since the 1999 launch of EU candidate country status, EU–Turkey relations have reached a new level of closer engagement. Across time, the relations demonstrate different levels of engagement and, accordingly, different narratives. Regarding the Turkish narratives of the EU, the EU is framed across time as follows: EU as a democratic anchor; EU as a disappointment; EU as an untrustworthy entity; EU as an enemy. As seen, Turkish narratives demonstrate a trend from EU-phoria to EU-phobia. In the end, it is important that EU–Turkey relations and Turkish narratives on the EU are not immune to domestic developments, especially those shaped by populist politics in the last two decades.

We reported a case of measles-induced acute disseminated encephalomyelitis (ADEM) in a 40-year-old immunocompetent adult. The patient presented a week after the development of respiratory symptoms and a cutaneous rash, and was admitted to hospital for altered mental status. Blood tests showed hyperleukocytosis, thrombopenia and cytolysis. A lumbar puncture was consistent with acute meningitis and the patient was initially treated with antiviral and wide broad-spectrum antibiotics. Serology and PCR for measles came back positive.

Background: Alzheimer's disease (AD) is a severe multifactorial neurodegenerative proteopathy associated with advanced age. Discrepancies in the renal function of these patients compared to geriatric patients with dementia have rarely been reported. In this study, we aimed to disclose the importance of associated renal changes for the pathogenesis of AD. Methods: Patients with AD (n = 107) and geriatric patients with dementia and without dementia (n = 124) (231 patients in total) from Dokuz Eylul and Cukurova University Hospitals were enrolled in the study. We measured serum Na, K, Cl, Ca, BUN, creatinine, total protein levels and MDRD [eGFR] in all groups. Results: From Izmir Center, the first study arm consisted of patients with AD dementia (n= 74), and the second arm included geriatric patients with dementia (n = 79). From Adana, 78 patients were recruited to the study, of which 33 were with AD and 45 were geriatric patients without dementia. When we analyzed comparatively the AD and geriatric dementia patients study arms, a statistically significant difference was observed both in the median age (p< 0.001), as well as in the biochemical parameters from Izmir Center: Na (p< 0.001), K (p< 0.001), Cl (p< 0.05), Ca (p< 0.001), BUN (p< 0.05), creatinine (p< 0.001), total protein (p< 0.001) and MDRD [eGFR] (p< 0.001). However, these were not significantly different between AD and geriatric patients without dementia in the Adana group. Conclusions: Our results indicate that renal function is prone to alterations in different age groups of patients with AD. However, there is no conclusive evidence that renal function is one of the risk factors in AD.

Boerhaave syndrome or spontaneous rupture of the oesophagus is a severe condition commonly misdiagnosed or unrecognized. Prognosis is poor even if the diagnosis is made promptly. We describe a case of Boerhaave syndrome diagnosed after the development of pneumomediastinum and cardiac arrest. Unfortunately, the patient died 48 hours after admission to the Intensive Care Unit. This entity requires a multidisciplinary management approach which may include conservative, surgical or endoscopic procedures.

We report a rare case of acute disseminated encephalomyelitis (ADEM) secondary to a primary Epstein-Barr (EBV) infection, in a 22-year-old male. Symptomatic infectious mononucleosis and ADEM are both quite uncommon conditions in this age group.

We report a case of brainstem infarction following a C5–C6 cervical transforaminal injection, a rare and serious neurological complication of this procedure. Cervical transforaminal steroid injection is a common therapy for patients with persistent cervical radiculopathy not relieved by conservative treatment, and is effective in 65–70% of cases. Unfortunately, this procedure may lead to serious complications such as neurological damage. These complications are rare but potentially fatal, as reported in our case. Complications could be due to three mechanisms: the technique itself, the cervical vascular anatomy and the properties of the product (corticoids). The neurological complications can be diagnosed through brain MRI. This case report focuses on the importance of a risk/benefit evaluation when performing this medical procedure.

The importance of adopting digital transformation for manufacturing companies is increasing day by day. In order to implement digital transformation process effectively, companies need tools based on Maturity Models (MM). This paper aims to present existing MMs in the literature in terms of their maturity levels and dimensions. According to the literature, it can be said that the maturity levels which are given in this study are similar to other categorical papers. On the other hand, the dimensions discussed herein represent more different perspectives than the maturity levels.

Production factors include labour, capital, nature and technology in traditional organization management. Nowadays, creativity, innovation and ability can be added to these. Competition is intense both in private and public sectors. Workforce can be said to be the main source enriching the organization and making it complex. What makes the organizational powerful is that talented personnel can make new ideas to be productive by using their creativity. From this point of view workforce productivity is important parameter in organizational efficiency. Workforce productivity in organizations where there are too many employees is primarily related to employ the personnel in a right position. The appointment of employees to work in accordance with their capabilities increase efficiency. This situation makes the structure of the workforce and make the organization be capable of competing with the rivals. The Assignment model of the type of linear programming models is a mathematical method used to match the right person for the right job. The coefficients of the variables in the objective function of the assignment model constitute potential contributions of employees. Factors that make contributions in different types of jobs are different and expert opinion is needed for the evaluation of these factors. In this study, more than 1000 people who work for Dokuz Eylul University as drivers, food handlers, technicians, office workers, securities and servants are taken into consideration. Gender, level of education, the distance from working place, marital status, number of children and tenure of these employees have been included in the analysis. Analytical hierarchy process which is a method of multi-criteria decision-making model has been preferred as a method. Specific criteria have been determined for each occupational group depending on this method. Later, weighted average for these criteria in question have been found. With these values belonging to the personnel, a person’s contribution coefficients have been calculated. These values are used in the assignment model. This model has been solved and evaluated as 0-1 integer programming. Model outputs that have been solved again by using additional constraints like task type and disability conditions and these are compared with the previous figures.

ÖZ: Üniversitelerin bünyesinde birçok şirket barınmaktadır. Bu şirketler üzerinde çalışan personeller zaman zaman ara eleman olarak üniversitelerin ihtiyaçlarına dönük birçok noktada istihdam edilmektedir. Personellerin kurum personel sisteminden bağımsız ve el yordamıyla kayıt altına alınması dönemsel hizmet alımıyla süreçlerin ilerlemesi kurumun faydalandığı iş gücünün doğru şekilde planlanmasını, kontrolünü ve koordinasyonunu yönetim açısından zorlaştırmaktadır. İşte bu noktada çalışma üniversite bünyesindeki şirketlerden alınan hizmet alımlarını kayıt altına almakta, iş gücünün planlaması, kontrolü ve koordinasyonu noktasında bir sistem geliştirmiştir. Gelişen iletişim ve bilişim teknolojilerinden faydalanarak bilgisayar ortamında çalıştırılan karar destek sistemi ve şirket personeli yönetim sistemi, iş gücü planlamasını insanın yapabileceği hatalardan arındırarak nesnel biçimde daha kısa zamanda tanımlayabilmekte ve çözüme ulaştırmaktadır. Kurumun farklı şirketler üzerinden hizmet alımı suretiyle çalıştırdığı personel sayısının oldukça yüksek olması (yaklaşık olarak 1800 çalışan), işbirliği bütçesinin büyüklüğü ve kurum içi ara eleman desteğinin önemi düşünüldüğü noktada çalışmanın önemi ortaya çıkmaktadır. Bu çalışmada, iş gücü planlamasında bir karar destek sistemi uygulaması gerçekleştirim süreci açıklanmıştır. Anahtar Kelimeler: Karar Destek Sistemi, İş Gücü Planlaması, Karar Destek Örneği. ABSTRACT: Many companies are hosted within the university structures. According to the requirements of the universities, employees of these companies are frequently deployed at various realms. Periodic procurement of services and keeping manual records of the employees, independent of the official personal registration system, complicates the workforce control and coordination for the institution managers. At this point, this study has developed a workforce planning, control and coordination system by recording the procurement of services supplied by the companies. A computer aided company personnel management and decision support system can provide faster and more objective workforce planning by purifying human errors and using contemporary communication and information technologies. In this study, according to the procurement of services approximately 1800 personnel have been registered and this shows the importance and size of the workforce procurement and a decision support system application development process has been explained. Keywords: Decision Support System, Workforce Planning, Decision Support Example.

Son yıllarda yaşanan küresel gelişmelerle birlikte artan tüketici ihtiyaç ve beklentileri teknolojik gelişmelerden yüksek bir şekilde etkilenmektedir. Pazarlama ve pazarlama iletişimi sektörleri dünyanın en hızlıdeğişen sektörleri olarak kabul edilmektedir. 2000′li yıllarda Internetin yaygın ve etkin kullanımıyla tüm sektörlerde pazarlamanın mantığıtamamen değişmiştir. Günümüzde pazarlama artık geleneksel metotların kullanıldığıortamlarıçoktan aşmıştır ve modern teknolojinin nimetlerini kullanmaya başlamıştır. Yepyeni, öngörülemeyen pazarlama biçimleri ortaya çıkmıştır ve bu süreç devam etmektedir. Müşteri ile ilişkinin bu kadar önemli olduğu günümüz rekabet koşullarında, müşteriler ile kurulan bu ilişkilerin kalıcıolabilmesi için işletmelerin; pazardaki eğilimleri ve gelişmeleri, müşterilerin beklentilerini, müşterilerin ihtiyaçlarınıiyi tanımalarıve müşteri odaklıbir pazarlama anlayışınıbenimsemeleri gerekmektedir. Geleneksel pazarın dengesini ürün/hizmet sağlayıcısıveya ürünün kendisi oluştururken, modern pazarlamanın dengesini müşteri ve onun ihtiyaçlarıoluşturmaktadır. Modern pazarlama; ürün odaklıdeğil, müşteri odaklıbir yaklaşımdır. Bu nedenle, günümüzde, işletmenin süreçlerinin, teknolojisinin ve kültürünün, müşterinin istek ve ihtiyaçlarıgözetilerek, yeniden organize edilmesi büyük önem kazanmıştır. Modern pazarlama anlayışıinsanlarıtüketim davranışlarıaçısından benzer ve farklıgruplara ayırmayı, hedefe yönelmişpazarlamayı, müşteri tatminini ve satın almanın tekrarlanmasınısağlayacak bütünleşik pazarlama mesajlarıgöndermeyi esas alır. Modernizm sonrasıveya ötesi olarak anlamlandırılan postmodernizm ve modernizm arasında kavramsal olarak zıtlıklar bulunmaktadır. 20. yüzyılın sonlarında, üretim tabanının bilgi teknolojilerine dayanmasıyla modern toplum da modern sonrasıaşamaya gelmiştir. Yeni ekonomi olarak da adlandırılan ve Internet kullanımınımerkeze alan bu yeni yönetim dünyası e-ticaret, e-iş, edevlet , aslında eski ve yeniyi bir arada yürüten bir geçişdönemini temsil etmektedir. Bu dönem, kültür, iletişim ve sanat gibi üst yapıkurumlarınıda etkileyerek postmodern dünyanın doğuşunu hızlandırmıştır. Pazarlama alanıda; ekonomi, psikoloji, sosyoloji, sosyal psikoloji, politik, kültürel ve yasal yaşamdan son derece etkilenen bir çerçevede konumlandığından postmodern kültür, pazarlamanın da yapısını, dokusunu, yöntem ve stratejilerini etkilemiştir. Günümüz işletmeleri açısından pazarlamanın öneminin bu denli artması, işletmeleri rekabette farklıpazarlama yöntemleri kullanmaya itmektedir. Bu çalışma da, farklı şirket örnekleri üzerinden postmodern pazarlama trendleri incelenmişve durum analizi yapılmıştır.

Sustainability for companies depends on increase customer satisfaction, effective and rational usage of resources and increases the volume of business. Both providing customer satisfaction and increase the productivity of business processes, effective process management is required. The effect of results that decision-makers change processes due to the working results, on customers is very important. In this study, a decision support application is realized with using computer technologies on customer satisfaction results access and evaluation tasks in customer relations management process.

In today’s challenging and tremendously changing business world, Information Security Management has become one of the most important topics with the relevant trade laws, IT laws, regulations and international standards. Despite all the existing bestpractices, years of experience, knowledge, methods, brand-new technologies and tools in information security management domain, everyone seems to be yet at serious stake due to misunderstandings, wrong implementations and unconscious approaches.In this study, the current situation regarding information security risks and problems are summarized by using the statistical surveys conducted in Turkey and other countries and the most common mistakes related with these problems are analyzed.Some effective and practical solutions that can be applied to communities and corporations in the short and long term are also given in this study.

Büyüme oranının tahmini ekonomi yönetimi, üretim yönetimi ve bütçe planlama için çok önemlidir. Bu amaçla hem zaman serileri hem de Yapay Zeka Teknikleri kullanılabilir. Bu teknikleri her ikisini de kullanarak böyle bir çalışma bu makale de yapılmıştır. Zaman serisi verisi ile yıllık büyüme oranıöğrenilebilir ve böylece değişkenlerin geçmişdeğerleri gelecek değerleri tahmin etmekte kullanılabilir. Bu makalede, yıllık büyüme oranı, bir otoregresiv model AR ve bir Yapay Sinir Ağları ANN modeli yardımıyla ANN simülatörü kullanılarak gerçekleştirilmiştir. Gelecek yıllarda büyüme oranları, ANN simülatörü ve zaman serisi analizi yardımıyla yukarıda bahsedilen parametrelere bağlıolarak tahmin edilmiştir. Sonra sonuçlar karşılaştırılmıştır. Sonuçlar göstermiştir ki ANN model yardımıyla elde edilen tahmin hatasıAR modeli ile elde edilenden daha küçüktür.

The competitive environment which grows in size and intensity every day with globalization, and the rapid change in technology require SMEs to fully adapt to the present conditions. SMEs, which are among the most fundamental factors in our economy, and the productivity of SMEs, which is one of the most important targets for SMEs, are investigated in this study. In this respect, a questionnaire study was conducted through vis-à-vis interviews held at 108 SMEs in Istanbul, the province that shelters the highest number of SMEs in our country. In this analysis, a general evaluation was made on the SMEs in Turkey.

Over the past two decades, there has been a growing interest in Europeanization, both within and beyond the European Union (EU). The impact of Eastern enlargement in 2004 on candidate and neighbourhood countries has attracted scholarly attention, and a consensus currently exists on the success of the EU’s transformative power through the employment of a conditionality mechanism. However, the limits of EU conditionality upon candidate countries and neighbourhood Europeanization, in addition to the problems experienced by the EU itself, have brought into question whether the end of Europeanization research is in sight. Considering this, we critically evaluate the issues discussed in the scholarship on Europeanization and review several points of interest in relation to EU candidate countries in the Western Balkans as well as Turkey.

This study was conducted to obtain information on the fatty liver syndrome in dairy cattle in Turkey. In this study 15 dairy cows belonging to the Livestock Research Center of Konya and 8 dairy cows raised by public and brought to our clinics in 10— 15 days after calving were used as research material. The biopsy of Liver and blood samples were taken from each cow belonging to the Livestock Research Center in the first week prior to and 1-2 weeks following the calving; whereas the same samples were obtained from the other experimental animals in two weeks after calving. The fatty liver syndrome was observed in cows brought to our clinics as mild in 12.5 %, moderate in 12.5 % and severe in 75 %, while it was found tobe mild in 73.3 %, moderate in 20 % and severe in 6.6 % in those that were kept in Livestock Research Center. It was determined that the concentration of FFA and GO T in blood sera were increased in connection to the fatty liver syndrome whereas the glucose concentration was reduced. As a result, it was concluded that the fatty liver syndrome was seen in higher percentage in the first two weeks after calving in dairy cattle that were raised by public, consequently the liver biopsy seems to be the only reliable method for the diagnosis of fatty liver syndrome.

In this study the blood sera collected from 238 cattle belonging to Livestock Central Research Institute of Konya were examined by micro-neutralisation test against parainfluenza-?) (PI-3) virus from the point of neutralizing antibodies. 116 cattle blood sera (49.57%) in a 1:5 dilution were found to be positive against PI-3 virus. It was determined that the antibody titers of positive sera ranged 1:5.63-1:317.

In this trial, the efficacy of Gonadotropin Releasing Hormone (FactrelR), administrated at the time of mating, on the pregnancy rate of dairy cows were studied. Sixty- nine cows were used as materials. Animals were divided in to two• groups and 25µg Factrel were injected to the first group of 33 aniınals and Placebo to the second group of 36 animals. Rectal exploration was performe.d. for estrous controls and pregnancy examinations were done post- mating 19- 21 and 60 days respectively. The pregnancy rates of Factrel injected group (81.81 %) were found higher than the controls (63.88%). The value was found significimtly higher between the two groups (P : The results were evaluated among the age groups. The differences in the pregnancy ra te were found higher in younger cows ( < 5 ages). There was a markeel improvement in the fertility rate in hormone treated cows after the relatively short interval ( < 60 days) between calving and mating. As a conclusion, the pregnancy rates could be improved with GnRH injections at the time of mating in the early postpartum cows.

In this study, the effects of penicilin - streptomycin on subclinical mastitisin dairy cattle was investigated during the dry period. The milk samples of 39 cows that were at the end of the lactation period were collected aseptically. They were examined bact;riologically whether they were infected or not. Pathogenic bacteriae were isolated from 46 milk samples. Then, 46 infected quarters were treated by penicillin- streptomycin combatination. To determine the effectiveness of the treatment, milk samples were collected from the mammary quarters after calving and were examined bacteriologically. After calving 84.78% of these infected quarters were found to be free from infection. Streptococci and E. Coli were eliminated by 100% and staphylococci and C. bovis infections were eliminated 85% during the same period.

Objectives: The aims of the study are to explore the morphological changes of olfactory bulb (OB) and olfactory sulcus in COVID-19 patients with associated olfactory dysfunction (OD) by measuring the OB volume (OBV) and olfactory sulcus depth (OSD) and to compare the measurement values with those of healthy individuals., Methods: Between March 2020 and January 2022, 31 consecutive hospitalized patients with a diagnosis of COVID-19 with anosmia and hyposmia who underwent brain magnetic resonance imaging and 35 normosmic control individuals were retrospectively included in the study. Bilateral OBV and OSD were measured and shape of the OB was determined based on the consensus by a neuroradiologist and an otorrhynolaryngologist., Results: The mean measurements for the right and the left sides for OBV (38 ± 8.5 and 37.1 ± 8.4, respectively) and OSD (7.4 ± 0.1 and 7.4 ± 1.0 mm, respectively) were significantly lower in COVID-19 patients with OD than those in control group (for the right and the left sides mean OBV 56.3 ± 17.1 and 49.1 ± 13.5, respectively, and mean OSD 9.6 ± 0.8 and 9.4 ± 0.8 mm, respectively). Abnormally shaped OB (lobulated, rectangular, or atrophic) were higher in patient group than those of controls.For the optimal cutoff values, OBV showed sensitivity and specificity values of 90.32% and, 57.14%, for the right, and 87.1% and 62.86% for the left side, respectively (area under the curve, 0.819 and 0.780). Olfactory sulcus depth showed sensitivity and specificity values of 90.32% and 94.29%, for the right, and 96.77% and 85.71%, for the left side, respectively (area under the curve, 0.960 and 0.944)., Conclusions: Decrease in OBV and OSD measurements in COVID-19 patients with OD at the early chronic stage of the disease supports direct damage to olfactory neuronal pathways and may be used to monitor olfactory nerve renewal while returning back to normal function., Competing Interests: The authors declare no conflict of interest., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)