1. The reduced cortical bone density in vertebral bodies: risk for osteoporotic fractures? Insights from CT analysis
- Author
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Yong Yang, Feng Liao, Xingbo Xing, Nianxi Liao, Dawei Wang, Xin Yin, Yihao Liu, Jidong Guo, Li Li, Huadong Wang, Chunyan Li, and Yang Zheng
- Subjects
Osteoporotic vertebral fractures ,Cortical bone mineral density ,Cancellous mineral bone density ,Quantitative computed tomography ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background There is a corresponding increase in the prevalence of osteoporosis and related fractures with the aging population on the rise. Furthermore, osteoporotic vertebral compression fractures (OVCF) may contribute to higher patient mortality rates. It is essential to conduct research on risk factors for OVCF and provide a theoretical basis for preventing such fractures. Methods We retrospectively recruited patients who had spine CT for OVCF or back pain. Demographic and CT data were collected. Quantitative computed tomography (QCT) software analyzed the CT data, using subcutaneous fat and paraspinal muscles as reference standards for BMD processing. BMD of cortical and cancellous bones in each patient’s vertebral body was determined. Results In this study, 144 patients were divided into non-OVCF (96) and OVCF (48) groups. Non-OVCF patients had higher cortical BMD of 382.5 ± 52.4 to 444.6 ± 70.1 mg/cm3, with T12 having the lowest BMD (p
- Published
- 2024
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