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Xiao-Li Yang,1,&ast; Wen-Yao Xie,2,&ast; Yi-Min Cai,3 Hong-Ying Tang,1 Mei-Yi Tao,3 Zhou-Min Shen,3 Hong-Jiao Chen4 1Department of Liver Surgery, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410005, People’s Republic of China; 2Interventional Operating Room, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410005, People’s Republic of China; 3Department of Nursing, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410005, People’s Republic of China; 4Medical College of Hunan Normal University, Changsha, 410013, People’s Republic of China&ast;These authors contributed equally to this studyCorrespondence: Yi-Min Cai, Nursing department, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), No. 61, Jiefang West Road, Changsha, 410005, People’s Republic of China, Tel +86 13787129085, Fax +0731-83928047, Email cyimin2022@163.comPurpose: To understand existing negative emotions in patients with coronary heart disease after percutaneous coronary stent implantation (PCI) and analyse its influencing factors.Methods: Patients with coronary heart disease after PCI in three tertiary hospitals in Changsha City from April to September 2018 were selected as the research subjects. The self-designed general information questionnaire assessed irritability, depression and anxiety (IDA) on a self-rating scale. It was used to examine patients’ existing negative emotions with coronary heart disease after PCI and analyse the influencing factors.Results: 203 questionnaires were distributed, and 202 valid questionnaires were recovered, with an effective recovery rate of 99.5%. The IDA score of patients with coronary heart disease after PCI was 17.01± 7.60 points, the incidence of negative emotions was 63.8%, and the incidences of depression, anxiety and irritability were 39.6%, 8.4% and 15.8%, respectively. Negative emotion was taken as the dependent variable and a patient’s general data, such as lifestyle and disease, as the independent variables. A univariate analysis was conducted to obtain gender, age, educational level, marital status, work status, per capita monthly household income, sleep status, etc. Seven factors were identified as the influencing factors of negative emotions in patients with coronary heart disease after PCI, and the difference was statistically significant (P< 0.05).Conclusion: Most patients with coronary heart disease after PCI tend to exhibit negative emotions such as anxiety and depression. Medical staff should attach great importance to evaluating any negative feelings in this group and take timely targeted intervention measures to prevent and mitigate the occurrence and development of these adverse emotions in patients with coronary heart disease after PCI.Keywords: coronary heart disease, postoperative PCI, negative emotions, influencing factors

Concentrations of heavy metals in 74 sediment samples from the Fenghe River, which originates from the north of the Qinling Mountains and flows through Xi'an, Shaanxi Province, China, were characterized by employing geographic information system (GIS) mapping, fuzzy synthetic assessment, and multivariate statistical analysis to determine the enrichment characteristics of heavy metals as well as their potential risks of pollution to sediments. Al, Cd, and Co were the major pollutants, with a high enrichment factor (EF) value. Heavy metal concentrations from samples near the paper plant were maintained at a high level. Significant enrichment of Al, Ba, Cr, Ni, Pb, and Co was found in the midstream and downstream, while high concentration of Cu occurred in the headwater stream. Based on the cluster and principal component analyses, sediment metals mainly came from the paper plants, agronomic practices, natural sources, and tourism, with a contribution of 51.59%, 23.01%, 14.21%, and 9.88%, respectively. Sediment pollution assessment explored using fuzzy theory based on the entropy method and toxicity coefficient showed that 26, 32, and 11 sites fell into Class III (slightly polluted), Class IV (moderately polluted), and Class V (heavily polluted), respectively, and their scores of membership degree in the polluted level were on the rise, suggesting a relatively high degree of sediment metal pollution in the study area. Closely related to the excessive industrial and agricultural applications, metal pollution in sediment is necessary to be addressed in the Fenghe River.

In this study, we proposed a Regional Probabilistic Risk Assessment (RPRA) to estimate the health risks of exposing residents to heavy metals in different environmental media and land uses. The mean and ranges of heavy metal concentrations were measured in water, sediments, soil profiles and surface soils under four land uses along the Shunde Waterway, a drinking water supply area in China. Hazard quotients (HQs) were estimated for various exposure routes and heavy metal species. Riverbank vegetable plots and private vegetable plots had 95th percentiles of total HQs greater than 3 and 1, respectively, indicating high risks of cultivation on the flooded riverbank. Vegetable uptake and leaching to groundwater were the two transfer routes of soil metals causing high health risks. Exposure risks during outdoor recreation, farming and swimming along the Shunde Waterway are theoretically safe. Arsenic and cadmium were identified as the priority pollutants that contribute the most risk among the heavy metals. Sensitivity analysis showed that the exposure route, variations in exposure parameters, mobility of heavy metals in soil, and metal concentrations all influenced the risk estimates.

Environmental quality of soils and sediments around water source area can influence the safety of potable water of rivers. In order to study the pollution characteristics, the sources and ecological risks of heavy metals Zn, Cr, Pb, Cu, Ni and Cd in water source area, surface soils around the waterway and sediments in the estuary of main tributaries were collected in Shunde, and ecological risks of heavy metals were assessed by two methods of potential ecological risk assessment. The mean contents of Zn, Cr, Pb, Cu, Ni and Cd in the surface soils were 186.80, 65.88, 54.56, 32.47, 22.65 and 0.86 mg · kg⁻¹ respectively, and they were higher than their soil background values except those of Cu and Ni. The mean concentrations of Zn, Cr, Pb, Cu, Ni and Cd in the sediments were 312.11, 111.41, 97.87, 92.32, 29.89 and 1.72 mg · kg⁻¹ respectively, and they were higher than their soil background values except that of Ni. The results of principal component analysis illustrated that the main source of Cr and Ni in soils was soil parent materials, and Zn, Pb, Cu and Cd in soils mainly came from wastewater discharge of local manufacturing industry. The six heavy metals in sediments mainly originated from industry emissions around the Shunde waterway. The results of potential ecological risk assessment integrating environmental bioavailability of heavy metals showed that Zn, Cu, Pb and Ni had a slight potential ecological risk. Cd had a slight potential ecological risk in surface soils, but a moderate potential ecological risk in surfaces sediments. Because the potential ecological risk assessment integrating environmental bioavailability of heavy metals took the soil properties and heavy metal forms into account, its results of risks were lower than those of Hakanson methods, and it could avoid overestimating the potential risks of heavy metals.

Three samples of jackfruit peel were prepared, which were processed through adding no additives, adding lactic acid bacteria (LAB), and adding both LAB and pectinase respectively. In order to find out the regular pattern of microbial flora, microbial flora of each sample was analyzed during ensiling. It was found out that growth of LAB reached its peak of 1.2×109～4.5×109 CFU/g FM in the 7th day of ensiling, growth of aerobic bacteria reached its peak of 3.5×105～1.8×106 CFU/g FM in the 3rd day of ensiling, and growth of yeast reached its peak of 2.8×105～4.6×105 CFU/g FM in the 3rd day of ensiling. All of the samples with different way of processing showed the same trend that growth of microbial flora number were increased gradually and then decreased. It were also found out that decrease of pH value had relation with LAB number, and decrease of pH value were lagged behind the peak number of LAB, and number of aerobic bacteria and yeast were decreased with reproducing of LAB and decline of pH value. Quality of silage added with LAB, and both pectinase and LAB were better than that with no additives.

Four samples of banana stems and leaves were prepared, which were processed through adding no additives, adding molasses, adding lactic acid bacteria (LAB), and adding both LAB and molasses respectively. In order to find out the regular pattern of microbial flora, microbial flora of each sample was analyzed during ensiling. It was found out that growth of LAB reached its peak of 6.4×107～7.8×109 CFU/g FM in the 6th day of ensiling, growth of aerobic bacteria reached its peak of 2.8×104～5.6×104 CFU/g FM in the 3rd day of ensiling, and growth of yeast reached its peak of 8.6×104～5.8×106 CFU/g FM in the 3rd day of ensiling. All of the samples with different way of processing showed the same trend that growth of microbial flora number were increased gradually and then decreased. It were also found out that decrease of pH value had relation with LAB number, and decrease of pH value were lagged behind the peak number of LAB, and number of aerobic bacteria and yeast were decreased with reproducing of LAB and decline of pH value. Nutrition constituent of forage made of banana stems and leaves was as follows: Dry matter 32.27%～33.59%，Crude protein 7.42%～8.16%, Acid detergent fiber 38.21%～41.43%. Quality of silage added with molasses, LAB and both molasses and LAB were better than that with no additives.

In order to investigate the nutritive and ensiling characteristics of banana stems and leaves, the chemical compositions of banana stems and leaves were analyzed and the effects of additives on fermentation quality were measured. The research results showed: Banana stems and leaves had high fiber content (stem>58% DM, leaf >72% DM), nitrogen free extract content (>50% DM), and water soluble carbohydrate contents (WSC>5% DM), with certain nutritive value. Tannins of banana stem and leaf were 0.11% DM and 0.24% DM. There were lactic acid bacteria (>105cfu/g FM) in the banana stems and leaves; they might be well preserved with some treatments.

Four lactic acid bacteria (LAB) strains named HN78, HN87, HN91 and HN113 were separated fromStylosanthes guianensis SW. of Hainan province, which were identified bacterially using the classical classification and the sequences of 16S rDNA. The results showed that four strains wereEnterococcus hirae,Enterococcus faecalis,Lactococcus lactisandLactobacillus plantarum. The capability of lactic acid production of HN113 and HN91 were better than HN78 and HN87.

In order to ensure better conservation and to increase the nutritive value of barley straw, the effects of lactic acid bacteria (LAB) and cellulase addition were studied. Two cellulases were Acremonium cellulase (AC) and Meiji cellulase (MC). Both cellulase and LAB addition decreased the pH values (P < 0.05) and increased lactic acid content when compared with the control, and their combination had further benefits over them alone. The efficiencies of improving fermentation quality were AC + LAB > MC + LAB > AC > MC > LAB. Cellulase addition significantly reduced ADF and crude fiber contents, and increased NFE content compared to the control (P < 0.05). The TDN contents of barley straw silages treated with AC, AC+LAB, MC and MC+LAB were increased by 11.9%, 15.5%, 7.0% and 10.8%, respectively.

Simple, inexpensive, preformed vanadium-Schiff base complexes were facilely prepared and used in enantioselective sulfoxidation. Both the amount of aqueous H 2 O 2 and reaction time greatly influenced the ee values and yields of chiral sulfoxides. High enantioselectivities (up to 99% ee) and reasonable yields (>40%) for various chiral sulfoxides were achieved by combining enantioselective sulfoxidation and appropriate concomitant kinetic resolution.

The title compound, C18H23NO3, has been obtained by the reaction of (1S,4R)-7,7-dimethyl-2-oxobicyclo­[2.2.1]heptane-1-carbonyl chloride with (S)-2-amino-3-phenyl­propan-1-ol. The carbonyl functionality of the carboxamide group and the hydr­oxy group are involved in O—H⋯O inter­molecular hydrogen bonds.

The influence of the application rates of cellulase preparation and glucose on silage fermentation at different temperatures was studied with the straw of naked barley (Hordeum vulgare L. emand Lam) and guineagrass (Panicum maximum Jacq.). Addition rate of cellulase and glucose, temperature and their interaction had significant effects on pH value, lactic acid content, butyric acid content and propionic acid content of naked barley straw silage and significant effects on all the parameters of guineagrass silage (P0.01). Temperature and interaction had significant effect on acetic acid content (P0.05) and no significant effect on NH(3)-N content of naked barley straw silage (P0.05). Under all the temperatures, the pH values of barley straw and guineagrass silages were reduced by cellulase and glucose addition even at the lowest rate (P0.05), compared with their corresponding control. Lactic acid contents of silages were the highest within the same temperature and same additive when glucose and cellulase were added at the highest rates, whereas the effect of cellulase and glucose addition on butyric acid production varied with their application rates and silage storage temperature. The addition rate of restricting butyric acid fermentation was lower at 20 degrees C than that at 30 degrees C, and it was the lowest at 40 degrees C where cellulase and glucose addition restricted butyric acid fermentation even at 0.1 g/kg and 10 g/kg, respectively, when compared to the control. While the addition rate was lower than the above level, cellulase and glucose addition also promoted butyric acid fermentation.

To investigate the prevalence of snoring in school age children from Changsha City, and study the correlation of snoring with attention deficit and hyperactivity-impulsivity.A total of 1 736 children aged 6 to 12 years were randomly sampled from five districts in Changsha City. Their parents completed the questionnaires about children's sleep conditions and the Attention Deficit Hyperactivity Disorder Diagnostic Scale-Parent Version.The total incidence rate of frequent snoring was 5.7%. Boys had higher incidence of frequent snoring than girls (7.5% vs 3.8%; x2=18.782, p0.01). The incidence of snoring in the 6-to 9-year-old group was higher than that of the 10-to 12-year-old group (x2=9.666, P0.01). The incidence of daytime sleepiness in the snoring group was higher than that in the non-snoring group (31.5% vs 25.9%; x2=6.678, p0.01). The incidences of larynx choking, sleep apnea, mouth breathing, hyperhidrosis, and awaking for unknown reasons or awaking by choke in the frequent snoring group were significantly higher than in the occasional snoring and the non-snoring groups (x2=37.035, 27.745, 51.341, 30.975, 45.972 respectively; all P0.01). The incidences of attention deficit (31.3%) and hyperactivity-impulsivity (18.2%) in the frequent snoring group were the highest, followed by the occasional snoring (16.2% and 9.9% respectively) and the non-snoring groups (13.9% and 8.8% respectively). There were significant differences in the incidence of both attention deficit (x2=20.592, p0.01) and hyperactivity-impulsivity (x2=9.067, p0.05) between groups.There is a high incidence of snoring in school age children from Changsha City. Snoring is correlated to attention deficit and hyperactivity-impulsivity. It is essential to pay attention to the mental growth and behavioral problems in children with sleep snoring.

To study the relationship between impulsivity and sleep disorders in children.A total of 1 736 children at ages of 6 to 12 years were randomly sampled from five districts of Changsha. Their parents completed the questionnaires about children's sleep conditions and behaviors (using Barratt Impulsiveness Scale 11th version).Five hundred and fifty-four children (31.9%) had sleep disorders. The incidence of sleep disorders in boys was significantly higher than that in girls (35.4% vs 28.3%; P0.01). The scores of attentional, motor, and non-planning impulsiveness factors as well as the total score of Barratt Impulsiveness Scale in children with sleep disorders were significantly higher than those in children without (P0.01). The incidence of daytime sleepiness (35.9%) in children with sleep disorders was significantly higher than that in children without (24.7%; P0.01). The scores of attentional, motor, and non-planning impulsiveness factors increased with the grade of sleep disorders, and reached a peak at the fifth grade. The children with frequent sleep snoring showed higher scores of above three impulsiveness factors than children without sleep snoring or having rare snoring (P0.01).Sleep disorders are associated with impulsivity in children. It is thus essential to pay close attentions to children's sleep for children with relatively high impulsiveness.

To study the sleeping time and its correlative factors in 2k12 year-old children in Changsha.A cluster sample with 3 756 children was randomly selected from Changsha, whose parents or care persons were interviewed with questionnaires about children's sleeping status from June 2006 to April 2007 by trained medical staff. One person was responsible for a questionnaire for one child.Two to twelve year-old children slept 10.60 hours a day. The average sleeping time every day was 12.26, 11.57, 11.33, 11.26, 10.95, 10.64, 10.62, 10.45, 10.28, 9.83, and 9.61 hours from 2 to 12 year-old children. The sleeping time in one day in each age group was different obviously but the same for boys and girls. The main factors that affected the sleeping time of children were: child's age, having pets or not, child's fixed pattern of sleeping time, methods of falling asleep, diet regulation, asthma, the mother's age, number of child delivery of mother, and mother's sleeping time.Sleeping time in a day decreases with the age increase in 2k12 year-old children. Many factors affected sleeping time of children, including the child's age, habits and environmental factors, diets, diseases, and mothers' conditions.

To study the sleep time and the prevalence of sleep disorders in children at ages of 2-12 years in Changsha City.A total of 3756 children at ages of 2-12 years were randomly sampled from five districts of Changsha City from June 2006 to April 2007. A questionnaire survey was performed on their parents.The average daily sleep time in the subjects was 10.60 hrs. The average daily sleep time among different age groups (1 year as a group separation) was different. It was 12.26, 11.57, 11.33, 11.26, 10.95, 10.64, 10.62, 10.45, 10.28, 9.83 and 9.61 hrs respectively in the 11 age groups of 2 to 12 years of age. The prevalence of sleep disorders in children at ages of 2-12 years was 40.9%, including frequent sleep snoring (8.2%), choke/gargling (1.5%), sleep apnea (0.8 %), sleep inquietude (7.6%), mouth breathing (4.9%), hyperhidrosis (22.6%), limbs spasm (3.2 %), sleep teeth grinding (9.5 %), sleep talking (5.5 %), sleep walking (0.9 %), nocturnal enuresis (2.5%), waking up by choke (1.9%), remaining wakefulness in the night due to too much daytime sleep time (1.5%), going to sleep too early (2.1%), night awakenings (1.6%), and screeching or crying during sleep (1.8%). The prevalence of different sleep disorders was different in children between boys and girls and among different age groups.The average sleep time in children at ages of 2-5 years is less than the reference value recommended by the domestic child health care textbook. There is a higher prevalence rate of sleep disorders in children at ages of 2-12 years in Changsha City than the reported data in other cities.