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C18H20CdN6O8, triclinic, P 1 ‾ $\overline{1}$ (no. 2), a = 6.1132(7) Å, b = 7.1270(9) Å, c = 12.3110(13) Å, α = 80.7010(10)°, β = 88.137(2)°, γ = 73.6530(10)°, V = 507.88(10) Å3, Z = 1, R gt(F) = 0.0285, wR ref(F 2) = 0.0744, T = 298(2) K.

Background: This study explores correlations of galectin-3 gene polymorphisms (rs4644, rs4652, and rs11125) with cervical cancer risk and prognosis in Chinese populations. Methods: A total of 126 patients with cervical cancer were selected to form the case group, and 102 healthy people were selected for the control group following a physical examination. 3 polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: The distribution frequencies of the CC+CA genotype of rs4652 and the AT+TT genotype of rs11125 in the case group were remarkably higher than those in the control group. rs4644 only had correlations with tumor diameter, while rs4652 and rs11125 had correlations with tumor diameter, FIGO staging, differentiation grades, clinical staging, lymph node metastasis (LNM), and treatment modality. The 5-years survival rate of patients with CC+CA of rs4652 was lower but the recurrence rate was higher compared to AA type patients. In contrast, AA type patients with rs11125 had a higher 5-year survival rate but a lower recurrence rate than those of AT+TT type. CC+CA genotype of rs4652, AT+TT genotype of rs11125, and treatment modality were independent factors related to overall survival and disease-free survival, and LNM was an independent factor related to OS. Conclusion: Our findings provide evidence that allele C of rs4652 and allele T of rs11125 in the galectin-3 gene may be risk factors for cervical cancer.

Aim This study investigated P21-activated kinase 1 (PAK1) and cell division control protein 42 homolog (CDC42) expression and their correlation with clinicopathological features and prognosis in cervical carcinoma. Methods Cervical carcinoma (n = 55), cervical intraepithelial neoplasias (CIN, n = 93), and normal cervix (n = 26) tissues were sampled. PAK1 and CDC42 expressions were determined using real-time quantitative polymerase chain reaction, Western blot and immunohistochemistry. Correlation analysis of PAK1 and CDC42 expression was performed using a Pearson correlation test. Survival rate was calculated using the Kaplan–Meier method. Independent prognostic factors were analyzed by Cox proportional hazard model. Results PAK1 and CDC42 expression were positively correlated in all tissues. PAK1 and CDC42 expression in cervical carcinoma tissues were higher than those in normal tissues. PAK1 and CDC42 protein expression in normal cervix, CINI, CINII, CINIII and cervical carcinoma tissues showed a gradually increasing trend. PAK1 and CDC42 expression were correlated with lymph node metastasis, the depth of tumor invasion, the degree of tumor differentiation, histological type and lymphovascular space invasion (LVSI; all P < 0.05). Cox regression analysis showed that the degree of tumor differentiation, PAK1 protein expression, histological type and LVSI are independent risk factors for prognosis of cervical carcinoma. Conclusion High PAK1 and CDC42 expressions are closely related to the clinicopathological features and poor prognosis of cervical carcinoma, serving as unfavorable prognostic factors.

In this paper designs PD-fuzzy sliding mode control for the quadrotor UAV to implement the trajectory-tracking mission. Firstly, dynamic model is introduced for quadrotor UAV. Secondly, the PD-fuzzy sliding mode control is proposed to make the real value of the UAV reach the desired value command, although the UAV is even with system uncertainties and disturbances. The convergence of the complete equations of motion of the UAV is proved by the Lyapunov stability theory. Computer simulation results illustrate the effectiveness of the proposed control schemes.

This study explores correlations of galectin-3 gene polymorphisms (rs4644, rs4652, and rs11125) with cervical cancer risk and prognosis in Chinese populations.A total of 126 patients with cervical cancer were selected to form the case group, and 102 healthy people were selected for the control group following a physical examination. 3 polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).The distribution frequencies of the CC+CA genotype of rs4652 and the AT+TT genotype of rs11125 in the case group were remarkably higher than those in the control group. rs4644 only had correlations with tumor diameter, while rs4652 and rs11125 had correlations with tumor diameter, FIGO staging, differentiation grades, clinical staging, lymph node metastasis (LNM), and treatment modality. The 5-years survival rate of patients with CC+CA of rs4652 was lower but the recurrence rate was higher compared to AA type patients. In contrast, AA type patients with rs11125 had a higher 5-year survival rate but a lower recurrence rate than those of AT+TT type. CC+CA genotype of rs4652, AT+TT genotype of rs11125, and treatment modality were independent factors related to overall survival and disease-free survival, and LNM was an independent factor related to OS.Our findings provide evidence that allele C of rs4652 and allele T of rs11125 in the galectin-3 gene may be risk factors for cervical cancer.

Unsaturated polyester resin/Graphite nanosheet composites were prepared using in situ polymerization under AC electric field which was applied during composite curing to induce orientation of graphite nanosheets. Scanning electron microscopy (SEM) has been applied to demonstrate the orientation of graphite nanosheets As a result, the percolation threshold was decreased to 0.25 wt% due to the orientation of the graphite nanosheets.

Four complexes have been prepared by reaction of rare earth nitrates with 2-acetylnaphthol-hydrazinehydrate (ANH) and phenanthroline. The complexes were characterized by IR spectra. The fluorescent properties of the europium and terbium complexes in solid and in DMSO solution were investigated and the effects of phenanthroline on the luminescent intensity of europium and terbium complexes also were studied. The results show that the europium and terbium ions formed stable complexes by coordinating to the nitrogen atoms and oxygen atoms of the ligands and the nitrates. And the complexes exhibited maximum fluorescence emissions in blue region.

Two Zn (II) complexes have been prepared by reaction of zinc acetate dihydrate with Schiff-base ligands. The IR spectra of complexes were measured. The luminescence properties of the Zn (II) complexes in solid and in methanol, ethanol and DMSO solution were investigated and the effects of organic solvents on the luminescent intensity of Zn (II) complexes also were studied. The results show that the Zn (II) ions formed stable complexes. The complexes exhibited maximum fluorescence emissions in blue region and the organic solvents have effect on the luminescence intensity.

The crystal structure of the title compound, C(10)H(10)N(2)·H(2)O, is stabilized by inter-molecular O-H⋯N, N-H⋯O and N-H⋯N hydrogen bonds.

In the title compound, C(14)H(14)N(2)O(3)S, the conformation is stabilized by an intra-moleclar O-H⋯N hydrogen bond and the dihedral angle between the aromatic ring planes is 79.55 (18)°. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds lead to [100] chains of mol-ecules.

In the title fused-ring compound, C(12)H(13)NO(3), the two five-membered C(3)NO rings both approximate to envelope conformations with C atoms in the flap positions. The OH group of the pendant CH(2)OH unit is disordered over two positions in a 0.528 (5):0.472 (5) ratio. One of the OH groups participates in an O-H⋯N hydrogen bond, generating centrosymmetric dimers in the crystal structure.

The title compound, C14H13NO2, exists in the keto form. An N—H...O hydrogen bond helps to establish the packing.

In the structure of the title compound, [Pb(C(13)H(10)NO(4)S)(2)(H(2)O)(5)], two S-O bonds and one C-N bond have lengths of 1.421 (9), 1.425 (8) and 1.268 (11) Å, respectively, which suggests they are double bonds. Mol-ecules form a two-dimensional layered structure via O-H⋯O and O-H⋯N inter-actions. The Pb atom adopts distorted cubo-octahedral coordination.

The structure of N ′-(2-acetyl-3-methylpyrazine)-4-toluenesulfonylhydrazide was determined by X-ray crystallography. The compound crystallized in a monoclinic system, and was characterized thus: P 21, a = 7.1172(16), b = 15.099(2), c = 7.5965(18)A, β = 97.261(2)°, Z = 2, V = 809.8(3)A3. The crystal structure was solved by direct methods and refined by full-matrix least-squares on F 2 to final values of R 1 = 0.0302 and wR 2 = 0.0762.

In the crystal structure of the title compound, C13H12N2O3, intra­molecular O—H⋯N and inter­molecular N—H⋯O hydrogen bonds occur.

In 1,10-phenanthroline pyridinium perchlorate, C12H8N2·C5H6N+·ClO4−, intra- and inter­molecular hydrogen bonding inter­actions dominate the crystal packing. The phenanthroline molecule, the cation and anion lie on crystallographic twofold rotation axes.

The conformation of the title compound, C17H12BrNO, is dictated by an intra­molecular O—H⋯N hydrogen bond.

In the title compound, C13H14N4O2S, the dihedral angle between the aromatic rings is 55.42 (14)°. In the crystal structure, an N—H...O hydrogen bond leads to chains of molecules along [001].

In the title compound, C17H21N3O3S, the dihedral angle between the aromatic ring planes is 84.2 (2)°. The pendant ethyl groups of the –N(C2H5)2 group are disordered over two sets of positions in a 0.84 (2):0.16 (2) ratio. The molecular conformation is stabilized by an intramolecular O—H...N hydrogen bond, and intermolecular N—H...O bonds lead to [010] chains in the crystal structure.

In the title compound, [Zn(C(14)H(13)N(4)O(2))(2)]·H(2)O, the Zn(II) centre is six-coordinated by four N and two O donors of two 2-acetyl-3-methyl-pyrazine (2-hydroxy-benzo-yl)hydrazonate ligands, and forms a distorted octa-hedral structure.

There are two mol-ecules in the asymmetric unit of the title compound, C(15)H(16)N(2)O(4)S, both of which are stabilized by an intra-molecular O-H⋯N hydrogen bond. Inter-molecular N-H⋯O hydrogen bonds lead to [101] chains of mol-ecules in the crystal structure.

In the title compound, [Cd(NO(3))(2)(C(4)H(5)N(3))(2)(H(2)O)(2)]·H(2)O, the Cd atom is seven-coordinated by two 2-amino-pyrimidine mol-ecules, two water mol-ecules, one bidentate nitrate anion and one monodentate nitrate anion. A network of N-H⋯O, N-H⋯N and O-H⋯O hydrogen bonds helps to consolidate the crystal structure.