1. Seroprevalence of the SARS-CoV-2 antibody in healthcare workers: a multicentre cross-sectional study in 10 Colombian cities
- Author
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Esperanza Muñoz, Diego Fernando Viasus-Perez, Eliana L Parra Barrera, Lucy Gabriela Delgado-Murcia, Ronald López, Jeadran N. Malagón-Rojas, Luisa Lagos, Julia Almentero, Eliana Téllez, Marien Palma, Claudia P Jimenez, Marisol Galindo, Edgar Antonio Ibáñez, Marcela Mercado-Reyes, Vivian Rubio, and Yezith G Toloza-Pérez
- Subjects
medicine.medical_specialty ,Cross-sectional study ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Health Personnel ,cross-sectional studies ,Colombia ,Antibodies, Viral ,Occupational safety and health ,Seroepidemiologic Studies ,Environmental health ,Health care ,Seroprevalence ,Medicine ,Humans ,Cities ,Workplace ,Socioeconomic status ,business.industry ,SARS-CoV-2 ,Risk of infection ,Public health ,public health ,Public Health, Environmental and Occupational Health ,COVID-19 ,Bayes Theorem ,Immunoglobulin G ,occupational health ,business - Abstract
BackgroundHealthcare workers are at increased risk of infection due to occupational exposure to SARS-CoV-2-infected patients. The objective of this study was to determine the seroprevalence of SARS-CoV-2 in healthcare workers in Colombia.MethodsThis study is a cross-sectional study focused on estimating the seroprevalence of SARS-CoV-2 antibodies in healthcare workers from 65 hospitals in 10 cities in Colombia during the second semester of 2020. The seroprevalence was determined using an automated immunoassay (Abbott SARS-CoV-2 CLIA IgG). The study included a survey to establish the sociodemographic variables and the risk of infection. A multivariate model was used to evaluate the association between the results of seroprevalence and risk factors.ResultsThe global seroprevalence of antibodies against SARS-CoV-2 was 35% (95% Bayesian CI 33% to 37%). All the personnel reported the use of protective equipment. General services personnel and nurses presented the highest ratios of seroprevalence among the healthcare workers. Low socioeconomic strata have shown a strong association with seropositivity.ConclusionThis study estimates the prevalence of SARS-CoV-2 infection among healthcare workers. Even though all the personnel reported the use of protective equipment, the seroprevalence in the general services personnel and nurses was high. Also, a significant difference by cities was observed.
- Published
- 2021