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Resumen Introduccion Las enfermedades cronicas impactan en la morbimortalidad y en la calidad de vida relacionada con la salud (CVRS) de los pacientes a nivel mundial. El impacto de las enfermedades reumaticas no ha sido totalmente reconocido. Objetivos Determinar la CVRS y evaluar areas especificas en artritis reumatoide (AR), osteoartritis (OA), diabetes mellitus, insuficiencia renal terminal, poblacion geriatrica y un grupo control. Pacientes y metodos Estudio transversal, realizado en el Hospital General de Morelia. Los sujetos cumplian criterios para AR, OA, diabetes mellitus, insuficiencia renal terminal, un grupo de poblacion geriatrica (≥ 65 anos) y un grupo control ≥ 30 anos. Se determinaron caracteristicas sociodemograficas y se aplicaron instrumentos: SF-36, escala visual analogica de dolor, valoracion global del paciente y medico, inventario para depresion de Beck, e instrumentos especificos (DAS-28, HAQ-Di, WOMAC, Diabetes Quality of Life [DQOL] y Kidney Disease Questionnaire of Life [KDQOL]). Mediciones bioquimicas: velocidad de sedimentacion globular (VSG), biometria hematica (BH), glucosa, HbA1C, creatinina y urea. Resultados Fueron evaluados 290 sujetos (un grupo control: 100, poblacion geriatrica 30 y 160 en los demas grupos). Se detectaron diferencias (p Conclusiones La CVRS en pacientes con AR es mala y equiparable a lo que sucede en pacientes con enfermedades cronicas (insuficiencia renal terminal y diabetes mellitus). Las enfermedades reumaticas deben considerarse padecimientos de alto impacto y por ello merecen mayor atencion.

Introduction Chronic diseases have a great impact on the morbidity and mortality and on the health-related quality of life (HRQoL) of patients around the world. The impact of rheumatic diseases has not been fully recognized. We conducted a comparative study to evaluate the HRQoL in different chronic diseases. Objectives The aim of the present study was to assess the HRQoL and identify specific areas affected in patients with rheumatoid arthritis (RA), osteoarthritis (OA), diabetes mellitus, and end-stage renal disease, in geriatric subjects and in a control group. Patients and methods We conducted a cross-sectional study, in a General Hospital in Morelia, Mexico. All patients met the classification criteria for RA, OA, diabetes mellitus, and end-stage renal disease; the geriatric subjects group was aged ≥65 years and the control group ≥30 years. Demographic characteristics were recorded, different instruments were applied: SF-36, visual analog scale for pain, patient's and physician's global assessments, Beck Depression Inventory and specific instruments (DAS-28, HAQ-Di, WOMAC, Diabetes Quality of Life [DQOL] and Kidney Disease Questionnaire of Life [KDQOL]). Biochemical measures: erythrocyte sedimentation rate, blood count, glucose, HbA 1 C, serum creatinine and urea. Results We evaluated 290 subjects (control group: 100; geriatric subjects: 30 and the rest of groups: 160). Differences were detected in baseline characteristics ( P P =.007). The worst HRQoL was observed in the end-stage renal disease group (SD: 48.06±18.84 x /SD). General health was the principal affected area in RA. Pain was higher in rheumatic diseases: OA (5.2±2.4) and RA (5.1±3). HAQ was higher in OA compared to RA (1.12±.76 vs .82±.82, respectively; P =.001). Forty-five percent of all subjects had depression. Conclusions The HRQoL in RA patients is poor and comparable to that of other chronic diseases (end-stage renal disease and diabetes mellitus). Rheumatic diseases should be considered as high impact diseases and therefore should receive more attention.