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831 results on '"Yeo, In-Seok"'

25. Optimization of Microbial Glycogen Production by Saccharomyces cerevisiae CEY1.

Author

Choi, Hyungseok, Yeo, In-Seok, Mwiti, Godfrey, Dinh, Toan Nguyen Song, Kang, Hyein, Kim, Chang Sup, and Kim, Jaehan

Subjects
GLYCOGEN, SACCHAROMYCES cerevisiae, ETHANOL, MASS production, CELL growth, CARBOHYDRATES
Abstract

Glycogen is a highly branched polyglucan utilized as a carbohydrate reserve in major living systems. Industrially, it is used as a prebiotic and in the nanoencapsulation of drugs and nutraceuticals. In this study, optimal fermentation conditions enabling the highest glycogen accumulation in Saccharomyces cerevisiae were experimentally evaluated for possible mass production. Production efficiency was assessed by comparing specific growth rates, specific glycogen production rates, and glycogen yields under each condition. The results demonstrated that fermentation at 30 °C with an aeration rate of 3 vvm using a medium containing 120 g/L glucose without ethanol was optimal for robust cell growth and maximum glycogen yield. Additionally, a rich medium outperformed a minimally defined medium, and a single sugar carbon source, as opposed to mixed sugars, resulted in significantly higher cell growth and glycogen yields (p < 0.05). The optimized fermentation parameters enabled a glycogen production rate of up to 0.232 ± 0.012 g-glycogen/g-cell/h and a glycogen yield of 0.603 ± 0.006 g-glycogen/g-glucose. These results provide meaningful information for future studies and/or large-scale glycogen production using S. cerevisiae. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Investigating the Influence of Varying Surface Conditions on Human Postural Control and Sensory Integration Strategies.

Author

Park, Seo-Yoon, Yeo, Sang-Seok, Kang, Tae-Woo, and Koo, Dong-Kyun

Subjects
*SENSORIMOTOR integration, *EQUILIBRIUM testing, *HUMAN beings
Abstract

This study investigated the effects of different surface conditions on postural stability in response to unexpected perturbations. Thirty healthy adults underwent balance assessments on flat, incline ramp, balance pad, and balance pad on incline ramp surfaces. The center of pressure (COP) displacement in the mediolateral (ML) and anteroposterior (AP) directions, the velocity, and the area were measured. We found that the flat and ramp conditions resulted in significantly lower COP ML (F(3, 87) = 38.272, p < 0.001, ηp2 = 0.569) and AP displacements (F(3, 87) = 89.177, p < 0.001, ηp2 = 0.755), velocity (F(3, 87) = 89.177, p < 0.001, ηp2 = 0.755), and area (F(3, 87) = 52.659, p < 0.001, ηp2 = 0.645) compared to the balance pad and balance pad on ramp conditions (p < 0.05). The use of a balance pad, particularly on a ramp, significantly increased all the COP measurements, suggesting greater challenges to postural control. Through these findings, we demonstrate the adaptability and limitations of the human postural control system in response to varying surface conditions and perturbations. [ABSTRACT FROM AUTHOR]

Published
2024
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