146 results on '"Yen, Jonathan"'
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2. Potent and uniform fetal hemoglobin induction via base editing
3. Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice
4. Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease
5. Base editing of haematopoietic stem cells rescues sickle cell disease in mice
6. DEVELOPMENT OF NEW GENE EDITING APPROACHES FOR BONE MARROW FAILURE AND MDS PREDISPOSITION SYNDROMES
7. Directed evolution of adenine base editors with increased activity and therapeutic application
8. Gene Therapy and Gene Editing for β-Thalassemia
9. OC 32 - DEVELOPMENT OF NEW GENE EDITING APPROACHES FOR BONE MARROW FAILURE AND MDS PREDISPOSITION SYNDROMES
10. Data from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
11. Supplementary Table 1 from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
12. Supplementary Table 3 from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
13. Supplementary Figures 1-6, Table 1B, 2, 4-6 from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
14. Editing human hematopoietic stem cells: advances and challenges
15. Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy
16. An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity
17. TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells
18. Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease
19. Base Editing for Therapeutic Induction of Fetal Hemoglobin in β-Thalassemia
20. Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations
21. A Novel RPS19-Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy
22. Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells
23. Hardcopy image barcodes via block-error diffusion
24. Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling
25. An Improved Method for Generating and Identifying Human Induced Pluripotent Stem Cells
26. Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application
27. Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia
28. Cancer pain: Magdi Hanna, Zbigniew (Ben) Zylicz (editors). Springer-Verlag London, 2013, 286 pages, ebook version available. ISBN 978-0-85729-229-2
29. Parallel boxing in B-spline intersection
30. Ligand binding to a G protein–coupled receptor captured in a mass spectrometer
31. Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+cell therapy to induce fetal hemoglobin for sickle cell disease
32. Selective in vivo metabolic cell-labeling-mediated cancer targeting
33. Degradable and biocompatible hydrogels bearing a hindered urea bond
34. Systematic Mapping of Gene-Editable Mutations in GATA2 and SAMD9/SAMD9L Syndromes
35. Efficient and Stable Makassar Base Editing in Nonhuman Primates
36. Reduced Polycomb Repressor Complex 2 (PRC2) Activity and Increased TP53 Activity Mediate Hematopoietic Stem Cell Dysfunction in RPS19-Mutated Diamond-Blackfan Anemia
37. CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles
38. Bioorthogonal oxime ligation mediated in vivo cancer targeting
39. Non-invasive, real-time reporting drug release in vitro and in vivo
40. Redox-responsive self-assembled chain-shattering polymeric therapeutics
41. Cancer pain
42. Enhanced non-viral gene delivery to human embryonic stem cells via small molecule-mediated transient alteration of the cell structure
43. Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells
44. Efficient Derivation and Genetic Modifications of Human Pluripotent Stem Cells on Engineered Human Feeder Cell Lines
45. Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
46. Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes
47. Generation of Induced Pluripotent Stem Cells in the Absence of Drug Selection
48. Pet fur color and texture classification
49. Knowledge discovery for better photographs
50. Peteye detection and correction
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