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4. Efficacy and adverse events profile of videolaryngoscopy in critically ill patients: subanalysis of the INTUBE study

Author

Anstey, Matthew, Colica, Sandra, Brewster, David, Simpson, Shannon, Regli, Adrian, O'Grady, Ross, Litton, Edward, Ferrier, Janet, Bartholdy, Roland, Tabah, Alexis, Bowen, David, Rowley, Rebecca, Gatward, Jonathan, Alonso, Julio, Varkey, Sneha, Palaniswamy, Vijayanand, Chimunda, Timothy, Reza, Syed T., Hossain, Mozaffer, Islam, Motiul, Hamid, Tarikul, Parotto, Matteo, Ajami, Samareh, Steel, Andrew, Del Sorbo, Lorenzo, Goffi, Alberto, Randall, Ian, Adhikari, Neill K.J., Mehesry, Tasneem H., Vera, Maria M., Bugedo, Guillermo, Labarca, Gonzalo, Silva, Monica, Ma, Wuhua, Li, Yongxing, Wu, Jiayan, Wu, Lun, Radivojević, Renata Curić, Matas, Marijana, Ivančan, Višnja, Pavlek, Mario, Mihaljević, Slobodan, Jumić, Aleksandra, Moguš, Mate, Tucić, Iva, Michalek, Pavel, Flaksa, Marek, Aguirre-Bermeo, Hernan, Tirape-Castro, Hugo, García Aguilera, Maria F., Montenegro, Diana Alvarez, Tutillo, Diego Morocho, Tutillo León, Jose A., Winiszewski, Hadrien, Piton, Gael, Aissaoui, Nadia, Augy, Jean-Loup, Champigneulle, Benoit, Zlotnik, Diane, Muller, Grégoire, Jacquier, Sophie, Hraiech, Sami, Guervilly, Christophe, Plantefeve, Gaetan, Contou, Damien, Ricard, Jean Damien, Besset, Sebastien, Colin, Gwenhael, Pouplet, Caroline, Mirouse, Adrien, Azoulay, Elie, Boissier, Florence, Frat, Jean-Pierre, Mercier, Emmanuelle, Salmon-Gandonnière, Charlotte, Lascarrou, Jean-Baptiste, Martin, Maelle, Ferre, Alexis, Legriel, Stephane, Bruel, Cedric, Philippard, Francois, Zarka, Jonathan, Chemouni, Frank, Hamzaoui, Olfa, Sztrymf, Benjamin, Brunin, Yannick, Pili-Floury, Sébastien, Constantin, Jean-Michel, Godet, Thomas, Maraffi, Tommaso, Dessap, Armand Mekontso, Jozwiak, Mathieu, Marin, Nathalie, Guitton, Christophe, Chudeau, Nicolas, Gros, Alexandre, Boyer, Alexandre, Papandreou, Eleni, Petsiou, Athanasia, Papanikolaou, Metaxia, Kyparissi, Aikaterini, Tileli, Maria, Makris, Alexandros, Tsiftsis, Dimitrios, El-Fellah, Nadia, Karametos, Ilias, Nakou, Evi, Chalkias, Athanasios, Arnaoutoglou, Eleni, Katsoulis, Panagiotis, Pouriki, Sofia, Vagdatli, Kyriaki, Dimitropoulou, Aikaterini, Kothekar, Amol, Baliga, Nishanth, Korula, Sara V., Philip, Sam, Singh, Lalit, Agrawal, Nipun, Jeswani, Deepak, Jeswani, Deepti, Jha, Simant, Singh, Nitesh, Bhattacharyya, Mahuya, Das, Amit, Kuragayala, Swarna D., Kesavarapu, Subba R., Shah, Bhagyesh, Kaushik, Shuchi, Sunil, Nilu, Gnanadurai, Kingsly, Singh, Atul K., Singh, Dinesh K., Khunteta, Sudhir, Gupta, Kulbhusahn, Sanyal, Rhik, Midya, Abhirup, Tyagi, Vijay N., Bendre, Prashant, Prashant, Kumar, Chaurasia, Satish, Mishra, Prasanna, Dash, Sampat, Sundrani, Omprakash, Lalwani, Jaya, Jain, Nikhilesh, Agrawal, Kehari, Ray, Banambar, Meher, Ranjan, Saravanabavan, Lakshmikanthcharan, Munusamy, Satheesh, Gupta, Manish, Ahmad, Meraj, Gopalakrishna, Kadarapura N., Suparna, Bharadwaj, Surath, Manimala R., Munta, Kartik, Jagiasi, Bharat, Srivastava, Anand, Sahu, Samir, Mrinal, Sircar, Kumar, Singh Sujeet, Shah, Mehul, Patel, Mayur, Bamane, Shrirang, Narkhede, Amit, Chawla, Rajesh, Chawla, Aakanksha, Maheshwarappa, Harish Mallapura, Manjunath, Ramya Ballekatte, Rahmani, Lua, Laffey, John G., Rona, Roberto, Benini, Annalisa, Russotto, Vincenzo, Rundo, Annalisa, Luzi, Annalisa, Esposito, Clelia, Nespoli, Moana R., Pradella, Andrea, Lungu, Ramona, Baccari, Laura, Chiumiento, Fernando, Mariano, Karim, Cotoia, Antonella, De Rosa, Silvia, Boni, Elisa, Palmese, Salvatore, Gammaldi, Renato, Spadaro, Savino, Santoro, Lida, Cracchiolo, Andrea N., Palma, Daniela M., Pinciroli, Riccardo, Giovannini, Ilaria, Calamai, Italo, Spina, Rosario, Cappellini, Iacopo, Tutino, Lorenzo, Bellissima, Agrippino, Maugeri, Jessica G., Riva, Ivano, Fabretti, Fabrizio, Brazzi, Luca, Sales, Gabriele, Montrucchio, Giorgia, Orsello, Alberto, Costamagna, Andrea, Canavosio, Federico G., Pelagalli, Lorella, Marcelli, Maria E., Cortegiani, Andrea, Tramarin, Jacopo, Musso, Stefania, Tarantino, Stefano, Di Giacinto, Ida, Licciardi, Anna L., Montini, Luca, De Pascale, Gennaro, Giacomucci, Angelo, Russo, Pierpaolo, Longhini, Federico, Garofalo, Eugenio, Ferluga, Massimo, Moro, Valeria, Cascella, Marco, Di Caprio, Barbara, Di Fenza, Raffaele, Nespoli, Francesca, Bassini, Ospedale E., Muttini, Stefano, Pezzi, Angelo, Elhadi, Muhammed, Ghula, Mohamed, Ahmed, Hazem Abdelkarem, Khaled, Ala, Elhadi, Ahmed, Alhadi, Abdulmueti, Mazlan, Mohd Z., Wan Hassan, Wan Mohd N., Hasan, Shahnaz, Jamaluddin, Muhamad F.H., Samat, Noryani Mohd, Ismail, Muhamad A., Alias, Anita, Hwa, Ngu Pei, Irtiza, Ismail Nahla, Khalidah, Hapiz, Kiok, Lee Chew, Nordin, Norbaniza Mohd, Wan Ismail, Wan N., Ali, Mohd N., Sánchez-Hurtado, Luis, Toledo-Salinas, Otoniel, Landaverde, Antonio, Sosa, Miguel A., Gonzalez, Mayra Martinez, Lopez Nava, Claudia L., San Juan Roman, Nandyelly, Gonzalez, Maria, Espinoza, Missael, González, Daira, Flores, Fernando, Pantoja Leal, Jesus N., Loza Gallardo, Luis R., Young, Paul, Mistry, Ravi, Browne, Alexander, Crone, Petra, Chandwani, Juhi, Hossein, Sazzad, Koul, Salman S., Aman, Rubina, Ali, Syed M., Akhtar, Shazia N., Jankowski, Milosz, Bielanski, Piotr, Mudyna, Wojciech, Franczyk, Pawel, Galkin, Piotr, Skowronski, Lukasz, Gaszynski, Tomasz, Piegat, Mariusz, Catorze, Nuno, Pinto, Marcia, Leonor, Tiago, Fernandes, Marco, Campos, Patricia, Aragão, Irene, Costa, Paulo F., Franco, Daniela G., Basto, Marta, Nogueira, Carla, Cunha, Rui P., Costa, Vasco, Lomivorotov, Vladimir, Nikitenko, Artem, Belsky, Vladislav, Furman, Mikhail, Magomedov, Marat, Baturova, Vera, Karelov, Alexey, Marova, Nadezhda, Almekhlafi, Ghaleb, Alghamdi, Adnan, Maseda, Emilio, Suarez de la Rica, Alejandro, Gonzalez, Jesus Flores, Ruiz, Miryam Pérez, Roca, Oriol, Santafe, Manel, Fernandez, Gemma Goma, Escudero-Acha, Patricia, González-Castro, Alejandro, Agvald-Öhman, Christina, Broman, Lina, Spangfors, Martin, Hannesdottir, Katrin, Persson, Elin, Rosell, Jon, Sperber, Jesper, Ohlsson, Annika, Von Seth, Magnus, Pedrotti, Niccolò, Wahlstrom, Carl, Meirik, Maria, Bandert, Anna, Krog, Ditte, Kuo, Lu-Cheng, Shin, Ming-Hann, Chien, Jung-Yien, Ku, Shih-Chi, Ruan, Sheng-Yuan, Huang, Chun-Kai, Yeh, Yu-Chang, Chao, Anne, Wang, Kuo-Chuan, Chiu, Ching-Tang, Lee, Chien-Chang, Chou, Nai-Kuan, Szakmany, Tamas, Jones, Benjamin, Jones, Laura, Della Torre, Valentina, Sinah, Ayush, Quayle, Alice, Cheetham, Olivia, Syed, Yadullah, Mensah, Kwabena, Edmunds, Christopher, Kaye, Callum T., Bauer, Philippe R., Odeyemi, Yewande E., Nates, Joseph, Laserna, Andres, Mosier, Jarrod, Hypes, Cameron, Gottesman, Eric, Mastroianni, Fiore, Fein, Daniel G., Zhao, Dawn, Fonseca Fuentes, Xavier E., Gallo de Moraes, Alice, Sandefur, Benjamin J., Khan, Akram, Matos, Dubier, Kaufman, David A., Lehr, Andrew, Bigatello, Luca, Bonney, Iwona, Lascarrou, Jean Baptiste, Tassistro, Elena, Antolini, Laura, Bauer, Philippe, Szułdrzyński, Konstanty, Camporota, Luigi, Putensen, Christian, Pelosi, Paolo, Sorbello, Massimiliano, Higgs, Andy, Greif, Robert, Grasselli, Giacomo, Valsecchi, Maria G., Fumagalli, Roberto, Foti, Giuseppe, Caironi, Pietro, Bellani, Giacomo, and Myatra, Sheila N.

Published
2023
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8. Immunometabolic features of natural killer cells are associated with infection outcomes in critical illness

Author

Chung, Kuei-Pin, primary, Su, Jia-Ying, additional, Wang, Yi-Fu, additional, Budiarto, Bugi Ratno, additional, Yeh, Yu-Chang, additional, Cheng, Jui-Chen, additional, Keng, Li-Ta, additional, Chen, Yi-Jung, additional, Lu, Ya-Ting, additional, Juan, Yi-Hsiu, additional, Nakahira, Kiichi, additional, Ruan, Sheng-Yuan, additional, Chien, Jung-Yien, additional, Chang, Hou-Tai, additional, Jerng, Jih-Shuin, additional, Huang, Yen-Tsung, additional, Chen, Shih-Yu, additional, and Yu, Chong-Jen, additional

Published
2024
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11. An observational study of microcirculation among healthy individuals by age and sex.

Author

Yang, Yun-Ping, Chiu, Ching-Tang, Chao, Anne, Yeh, Yu-Chang, Sun, Wei-Zen, Liu, Chih-Min, and Chan, Wing-Sum

Subjects
OLDER people, MICROCIRCULATION, SYSTOLIC blood pressure, AGE differences, SCIENTIFIC observation
Abstract

OBJECTIVE: This study measured normal ranges of microcirculatory parameters in healthy individuals and investigated differences in parameters by age and sex. METHODS: Participants were enrolled into three groups with equal numbers of male and female: young (20–39 years), middle-aged (40–59 years), and elderly (60–79 years). Sublingual microcirculation images were obtained using the incident dark field (IDF). RESULTS: A total of 75 female and 75 male healthy individuals were enrolled. The elderly group had a higher TVD (26.5 [2] vs. 25.2 [1.8]; p = 0.019) and a lower PPV (97 [2] vs. 98 [3]; p = 0.03) than did the young group. In the elderly group, systolic blood pressure (SBP) and mean arterial pressure (MAP) were moderately and positively correlated with MFI score (r = 0.407, p < 0.05, and r = 0.403, p < 0.05, respectively). The female participants had a lower MFI score than did the male participants (2.9 [2.8–3] vs. 3.0 [2.9–3]; p = 0.015). CONCLUSIONS: This study revealed the range of microcirculatory parameters between different ages and sexes in healthy individuals. We found that blood pressure levels were correlated with microcirculatory parameters, especially in elders and female. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Early prediction of delirium upon intensive care unit admission: Model development, validation, and deployment

Author

Wang, Man-Ling, primary, Kuo, Yu-Ting, additional, Kuo, Lu-Cheng, additional, Liang, Hsin-Ping, additional, Cheng, Yi-Wei, additional, Yeh, Yu-Chen, additional, Tsai, Ming-Tao, additional, Chan, Wing-Sum, additional, Chiu, Ching-Tang, additional, Chao, Anne, additional, Chou, Nai-Kuan, additional, Yeh, Yu-Chang, additional, and Ku, Shih-Chi, additional

Published
2023
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19. Successful management of delirium with dexmedetomidine in a patient with haloperidol-induced neuroleptic malignant syndrome: A case report

Author

Yang, Chi-Ju, Chiu, Ching-Tang, Yeh, Yu-Chang, and Chao, Anne

Subjects
Case report, Haloperidol, Delirium, Neuroleptic malignant syndrome, Alpha-2 adrenergic agonists, General Medicine, Dexmedetomidine
Abstract

BACKGROUND We report a case of lorazepam-induced agitated delirium treated with haloperidol, which in turn triggered the onset of neuroleptic malignant syndrome (NMS). The latter condition, a medical emergency, was effectively treated with medical treatment and dexmedetomidine, a versatile and highly selective short-acting alpha-2 adrenergic agonist with sedative-hypnotic and anxiolytic effects. CASE SUMMARY A 65-year-old man with a history of bipolar disorder presented to the emergency department with severe abdominal discomfort after binge eating. During his hospital stay, he received intravenous lorazepam for insomnia. On the next day, he became delirious and was thus treated with seven doses (5 mg each) of haloperidol over a 48 h period. Signs of NMS (hyperthermia, rigidity, myoclonus of upper limbs, impaired consciousness, tachypnea, and dark urine) became apparent and haloperidol was immediately suspended and brisk diuresis was initiated. On intensive care unit admission, he was confused, disoriented, and markedly agitated. Dexmedetomidine infusion was started with the goal of achieving a Richmond Agitation-Sedation Scale score of -1 or 0. NMS was resolved gradually and the patient stabilized, permitting discontinuation of dexmedetomidine after 3 d. CONCLUSION Dexmedetomidine may be clinically helpful for the management of NMS, most likely because of its sympatholytic activity.

Published
2022

20. Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

Author

Rashidi, Mahboobeh, Hamid, Hytham K S, Saidahmed, Elfayadh, Karar, Ali Adil Ali, Mc Cree, Melanie, Adeola, Fowotade, Idowu, Olusola, Oladimeji, Motunrayo, Asiyanbi, Gabriel, Desalu, Ibironke, Olatosi, John O, Ugwu, Euphemia Mgbosoro, Yakubu, Saidu Yusuf, Misra, Krushna Chandra, Sheshala, Kaladhar, Mukherjee, Sudipta, Ghosh, Pralay, Chandran, Jagadish, Dsilva, Carol, Baby, Sailaja K, Renuka, M K, Patel, Mayur, Rathod, Darshana, Datta, Avijatri, Bose, Payel, Siddiqui, Suhail Sarwar, Ozair, Ahmad, Muzaffar, Syed Nabeel, Shekhar, Saurav, Singh, Ritu, Pahuja, Madhumati, Jain, Nikhilesh, Rubina, Noor Ahmedi, Vaidyanathan, R, Samdani, Pratit, Nimbolkar, Janardan, Sharma, Priya, Karmakar, Saurabh, Sharma, Ankur, Kothari, Nikhil, Baronia, Arvind, Gurjar, Mohan, Islam, Mohammad Motiul, Hasan, Rajib, Huq, Shihan Mahmud Redwanul, Rabbani, Raihan, Hewer, Tayne, Thompson, Patricia, Sligl, Wendy, Kutsogiannis, Demetrios J, McCoshen, Lorena, Baig, Nadia, Burma, Yaroslava, Sokhan, Anton, Renaud, Paul Jean, Humphreys, Miss Sally K, Tilley, Rebecca E, Patel, Jamie, Attwood, Ben, Chikungwa, Moses, Jackson, Matthew, Zaki, Ahmed, Banach, Dorota, Torre, Valentina Della, Marsden, Nicholas, Antrolikar, Supriya, Kannan, Santhana, Mckee, Rachel, Mcguigan, Peter, Baikady, R Rao, Jhanji, S, Black, E, Husain, A, Loftus, S, Tatham, Kate, Hall, Daniel, Longbottom, Rebecca, Baumer, Tom, Szakmany, Tamas, Roshdy, Ashraf, Sanderson, Amanda, Ritzema, Jenny, Keegan, Allison, Cerman, Jaroslav, Graham, Clive, Smith, Tim, Cole, Stephen, Cobb, Katherine, Parcell, Benjamin J, Angell, Hollie, Hugill, Keith, Franke, Uwe, Arias, Sonia Sousa, Templeton, Maie, Lennard, James, Macfie, Caroline, Johnson, Aimee, Dolan, Rachael, Yonan, Aimee, Soltan, Marina, Bajaj, Manan, Goyal, Shraddha, Mulhi, Randeep, Torlinski, Tomasz, Khade, Reena, Tinaslanidis, George, Zormpa, Artemis, Raj, Ashok, Kent, Melanie, Cowton, Amanda, Faulkner, Maria, Tizard, Kate, Rojo, Roceld, Antcliffe, David, Ercole, Ari, Morris, Andrew Conway, Routledge, Matthew, Aktas, Sabahat Cagan, Batirel, Ayse, Akyol, Ahmet, Goksu, Senay, Ersoy, Yasemin, Bayindir, Yasar, Altin, Nilgün, Gürbüz, Yunus, Erdoğan, Cem, Ozgen, Cansu, Sungurtekin, Hulya, Evik, Guliz, Ersoz, Gulden, Guzeldag, Seda, Bilir, Yeliz, Saracoglu, Kemal Tolga, Eroglu, Ahmet, Aksoy, Firdevs, Koksal, Iftihar, Karaali, Ridvan, Saltoglu, Nese, Cakmak, Rumeysa, Tunay, Burcu, Yilmaz, Mesut, Akdogan, Ozlem O, Baykam, Nurcan N, Çolak, Onur, Agalar, Canan, Sari, Ali, Gundogan, KÜRŞAT, Akbas, Türkay, Çolak, Sait, Demiray, Emine Kubra Dindar, Erol, Çiğdem, Ozturk, Barcin, Telli, Murat, Kurt, Ibrahim, Kalem, Ayşe Kaya, Kayaaslan, Bircan, Talan, Leyla, Altintas, Neriman Defne, Ceyhun, Solakoğlu, Mehtap, Selcuk, Kusoglu, Hulya, Kocagoz, Sesin, Timuroglu, Arif, Aslan, Abdullah Tarik, Akova, Murat, Abed-Maillard, S, Pagani, Jl, Jakob, Stephan, Prazak, Josef, De Geer, Lina, Åkerlund, Joyce, Edin, Alicia, Haney, Michael, Svensson, Carl Johan, Spahic, Dzana, Sjövall, Fredrik, Gallego, Alberto Orejas, Blasco-Navalpotro, Miguel Angel, Novo, Mariana, Ayestaran, J Ignacio, De La Rica, Alejandro Suarez, Maseda, Emilio, Rodriguez, Dra M, Asensio, Dra Mj, Prieto, Emilio Garcia, Espina, Lorena Forcelledo, Salgado, Dra Maria, Ubeda, Alejandro, Gomà, Gemma, Santos, Emilio Diaz, Quesada, María Dolores, Raguer, Laura, Roig, Regina, Catalan, Beatriz, Armestar, Fernando, Bermudez, Rosana Munoz, Arnillas, Maria Pilar Gracia, Amerigo, Joaquin Amador, Flores, Matias, Vera, Paula, Casares, Vanessa, Martinez, Maria, Rocca, Ricard Ferrer, Furman, Mikhail, Belskiy, Vladislav, Chukina, Maria, Vistovskaya, Natala, Eremenko, Aleksandr, Gaigolnik, Denis, Tribulev, Maksim, Zubareva, Nadezhda, Magomedov, Marat, Meleshkina, Yulia, Anderzhanova, Anastasia, Gritsan, Alexey, Lungu, Olguta, Grigoras, Ioana, Marcu, Alexandra, Popescu, Mihai, Tomescu, Dana, Predoi, Cornelia Elena, Filipescu, Daniela Carmen, Cobilinschi, Cristian, Grintescu, Ioana Marina, Bubenek-Turconi, Serban, Valeanu, Liana, Mendes, António Carvalho, Pereira, Énio, Moura, José Pedro, Nunes, Cristina, Pascoalinho, Dulce, Queiró, Joana, Ledo, Sara, da Costa, Tito, Molinos, Elena, Cunha, Rui Pedro, Costa, Vasco, Duarte, Tiago, Botelho, Isabel, de Figueiredo, António Manuel Pereira, Teresa, Ana, Krystopchuk, Andriy, Pinto, Ana Rios, Marques, Ana Josefina Pinheiro, Alves, Madalena, Guimarães, Nádia, Pereira, Tiago, Cartoze, Nuno, Bisanti, Alessandra, Martin-Loeches, Ignacio, Pietraszek-Grzywaczewska, Iwona, Peichota, Mariusz, Broda, Hanna, Nowakowski, Tomasz, Wasowska, Dominika, Walczak-Wieteska, Paulina, Kotkowska, Anna, Bojko, Jozef, Szczesniak, Anna, Komorowska, Irmina Kaptur, Tamowicz, Barbara, Mikstacki, Adam, Rizzo, Anna Chiara, Cotoia, Antonella, Fiorelli, Silvia, Rocco, Monica, Covotta, Marco, Pelagalli, Lorella, Di Guardo, Andrea, Bellina, Davide, Ippolito, Mariachiara, Cortegiani, Andrea, Battaglini, Denise, Pelosi, Paolo, Schlevenin, Maria Grazia, Zuccaro, Francesco, Lodi, Giovanni, Daroui, Ivan, Mirabella, Michele, Porcile, Elisa, Gratarola, Angelo, Giacobbe, Daniele Roberto, Di Gravio, Valentina, Vargas, Joel, Carelli, Simone, Montini, Luca Maria, De Pascale, Gennaro, Sales, Gabriele, Montrucchio, Giorgia, Papathanakos, Georgios, Kouroulas, Vasilios, Retselas, Ioannis, Theodorou, Vasiliki, Marouli, Diamantina, Malliotakis, Polychronis, Almiroudi, Mariota Panagiota, Dimopoulos, Georges, Ali, Fadi, Papageorgiou, Eirini, Athanasa, Zoi, Sakagianni, Aikaterini, Chantziara, Vasiliki, Efthymiou, Anna, Georgopoulou, Maria, Chatzis, Marinos, Sakkalis, Anastasios, Nikolaou, Charikleia, Kogkopoulos, Evangelos, Oikonomou, Marina, Kampolis, C, Papanikolaou, M, Marmanidou, Kyriaki, Paskalis, Harry, Karaiskos, Ilias, Moldovan, Leora, Matei, Mariana Kristina, Koutsoukou, Vasiliki, Romanou, Vasiliki, Vasileiou, Maria, Renta, Foteini, Papoti, Sofia, Iasonidou, Cristina, Kaimakamis, Evangelos, Soulountsi, Vasiliki, Fildisis, Georgios, Psallida, Vasiliki, Smyrniotis, Dimitrios, Arvaniti, Kostoula, Temirov, Talgat, Merenkov, Yevgeniy, Babashev, Baurzhan, Kaligozhin, Zhannur, Bazhykayeva, Yelena, Mugazov, Miras, Ymbetzhanov, Yerlan, Viderman, Dmitriy, Metz, Carlos, Lepper, Philippe, Wempe, Carola, Gottschalk, Antje, Schmidt, Karsten, Dubler, Simon, Pasieka, Bastian, Petros, Sirak, Thomas-Rueddel, Daniel, Bloos, Frank, Hoheisen, Sandra, Bracht, Hendrik, Klouche, Kada, Imzi, Nadia, Dahyot-Fizelier, Claire, Fartoukh, Muriel, Voiriot, Guillaume, Aparicio, Christelle, Siami, Shidasp, Le Guennec, Loïc, Demeret, Sophie, Silva, Stein, Sarton, Benjamine, Roger, Claire, Lefrant, Jean-Yves, Larcher, Romaric, Badre, Gaëtan, Kalfon, Pierre, Razazi, Keyvan, Dessap, Armand Mekonted, Baudry, Thomas, Argaud, Laurent, Smonig, Roland, Louis, Guillaume, Bourenne, Jérémy, Gainnier, Marc, Barbier, François, Djanikian, Flora, Perrigault, Pierre-François, Foucrier, Arnaud, Janny, Sylvie, Weiss, Emmanuel, Bruel, Cédric, Tran, Marc, Philippart, François, Paulet, Rémi, Thyrault, Martial, Duprey, Matthieu, Garcon, Pierre, Mira, Jean-Paul, Le Souhaitier, Mathieu, Bortolotti, Perrine, Kipnis, Eric, Duburcq, Thibault, Coupez, Elisabeth, Souweine, Bertrand, Nica, Alexandru, Alfandari, Serge, Leroy, Olivier, Rosman, Jérémy, Mateu, Philippe, Escudier, Etienne, Guesdon, Charlotte, Massri, Alexandre, Beuzelin, M, Marchalot, A, Le Meur, Anthony, Auchabie, Johann, Castanera, Jérémy, Dulac, Thierry, Montravers, P, Zappela, N, Patrier, Juliette, Timsit, Jean-François, Arbelot, Charlotte, Leone, Marc, Lasic, Hrvoje, Nikolic, Mario, Sakan, Sanja, Persec, Jasminka, Brajkovic, Ana Vujaklija, Radonic, Radovan, Filipovic-Grcic, Ina, Custovic, Aida, Zlojutro, Biljana, Kovacevic, Pedja, Opdenacker, Godelive, De Waele, Elisabeth, Wittebole, Xavier, Serck, Nicolas, De Schryver, Nicolas, Misset, Benoît, Layos, Nathalie, Noel, Cindérella, Biston, Patrick, Haentjens, Lionel, Henin, Pierre, Mesland, Jean-Baptiste, Vanderhaeghen, Sofie F M, Bourgeois, Marc, Denys, Wouter, Hollevoet, Isabelle, De Waele, Jan, De Bus, Liesbet, Tomas, Ernesto Deloya, Perez-Nieto, Orlando R, Tejeda-Huezo, Brigitte, Sánchez-Hurtado, Luis, Ñamendys-Silva, Silvio A, Davalos-Alvarez, Adrian, Dominguez-Cherit, Jose G, Lomeli-Teran, Manuel, Villafuerte, Missael Vladimir Espinoza, Herrera, Mara Ocotlan Gonzalez, Aguilar, Candy Garcia, Leal, Jesús Nicolás Pantoja, Castillo, Roberto Alejandro, Hermosillo, Mariana, Romero-Gonzalez, Juan P, Reyes, Luis Felipe, Montefiore, Pablo, Nuccetelli, Yanina, Alonzo, Microbiologa Irene, Aparicio, Dra Marta, Segura, Matías, Fernández, Rubén, Lopez, Patricia Mabel, Acevedo, José Oscar, Morvillo, Lic Natalia, Centeno, Pablo, Sellami, Walid, Turki, Olfa, Bouaziz, Mounir, Bakr, Lubna, Al-Jadaan, Mohammad, Abu-Sayf, Natalia, Chaaban, Mohammad Karam, Aljabbary, Ahmed, Awad, Maher, Almekhlafi, Ghaleb A, Elrabi, Omar, Sallam, Hend, Nissar, Shaikh, Lance, Marcus, Karic, Edin, Elbuzidi, Abdurahaman, Hssain, Ali Ait, Jayyab, Mustafa Abu, Amro, Sarah, Belkhadir, Z, Ghannam, A, Hachimi, Abdelhamid, Younes, Oujidi, Housni, Brahim, Zeggwagh, Amine Ali, Dendane, Tarek, Wajdi, Maazouzi Ahmed, Mouhssine, Doumiri, Kanjaa, Nabil, Boukatta, Brahim, Seddiki, Rachid, Serghini, Issam, Hasan, Rabab Shaban Ben, Hasan, Hayat Ben, Jobran, Rania, Hdada, Aisha Khaled, Abousnina, Fathi A, Abdulwahed, Eman, Taher, Ahmed Sa, Bouhuwaish, Ahmad, Bilkhayr, Hala, Almiqlash, Bushray, Homaidan, Ahmed Gaber Sadik, AliAli, Almajdoub Mohammed, Aqeelah, Ahmed, Gamra, Marwa, Buimsaedah, Ahmad, Fares, Aya, Ibrahim, Rebecca, Abilama, Fayez, Diab, Adei, Harara, Belal, Levin, Phillip, Belman, Daniel, Rigler, Merav, Kagan, Ilya, Singer, Pierre, Ahmed, Abdullah Khudhur, Tabatabaei, Seyed Mohammad Nasirodin, Tajvidi, Ramin, Masjedi, Mansoor, Sarshad, Hakimeh, Sabetian, Golnar, Dabiri, Gholamreza, Aalinezhad, Fatemeh, Mahmoodpoor, Ata, Zargar, Mohammad Amin, Kiani, Arash, Amiri, Fereshteh, Javaherforoosh, Fatemeh, Baghbanian, Reza, Soltani, Farhad, Savaie, Mohsen, Ahmadi, Fatemeh, Kashipazha, Davood, Mehraban, Zahra, Borsi, Seyed Hamid, Ouhadian, Maryam, Zand, Farid, Hemead, Hanan M, Awad, Ahmed K, Elbadawy, Merihan A, Elsayed, Ahmed, Elmandouh, Omar, Aldhalia, Amer, Saber, Ahmed, Elbahnasawy, Mohamed, Mostafa, Tarek, Osman, Nermin, Barsoum, Mina, Elhadidy, Amr, Alsisi, Adel, Houfi, Ashraf El, Nadeem, Rashid, Chiewroongroj, Supattra, Apichatbutr, Yutthana, Wongsurakiat, Phunsup, Ku, Shih-Chi, Kuo, Li-Kuo, Hu, Ting-Yu, Cia, Cong-Tat, Chou, Nai-Kuan, Yeh, Yu Chang, Ng, Louis Xiang Long, Ng, Kangqi, Quah, Jessica Lishan, Lim, Jia Yan, Ong, Caroline Yu Ming, Li, Andrew Yunkai, Goh, Ken Junyang, Kwa, Andrea Lay Hoon, Lie, Sui An, Ng, Shin Yi, Goh, Qing Yuan, Lim, Sung Yoon, Park, Seung Yong, Park, Sunghoon, Lee, Sang-Min, Jeon, Kyeongman, Ali, Saedah, Mazlan, Mohd Zulfakar, Azman, Abd Hamid, Tong, Lee Kok, Noor, Zuraini Md, Rahman, Hamizah Bt Abdul, Fong, Kean Khang, Wong, Siong Ling Danny, Liew, Mun Thing, Visvalingam, Sheshendrasurian, Pheng, Lee See, Jamaluddin, Muhamad Fadhil Hadi, Hasan, M Shahnaz, Takaki, Shunsuke, Kato, Hideaki, Atobe, Kaori, Saito, Hiroki, Rinka, Hiroshi, Omori, Koichiro, Fujitani, Shigeki, Yoshida, Hideki, Nagashima, Michio, Mishima, Yuka, Shigemitsu, Hidenobu, Kuriyama, Akira, Matsuyoshi, Takeo, Makino, Jun, Hosokawa, Koji, Hashimoto, Satoru, Yamasaki, Masaki, Karumai, Toshiyuki, Hayashi, Yoshiro, Geng, Nan, Peije, Li, Weifeng, Xie, Ye, Ling, Qin, Bingyu, Wang, Yan, Yan, Jing, Huang, Min, Zhou, Suming, Hu, Chungfang, Ye, Jilu, Zhang, Min, Yin, Yongjie, Wang, Jinfeng, Wang, Ruilan, Yin, Chengfen, Xu, Lei, Mingmin, Chen, Wusi, Qiu, Zhao, Juan, Zhao, Peng, Wang, Hao, Chen, Xiaomei, Luo, Jili, Qian, Chuanyun, Zhen, Wang, Wei-Hua, Lu, Jianfeng, Xie, Haibo, Qiu, Sridharan, Dhadappa Damodar, Sudhirchandra, Shah, Moorthi, P Dhakshina, Mon, Tomas, Walid, Haji Adi Muhamad Ibnu, Tabah, Alexis, Buetti, Niccolò, Staiquly, Quentin, Ruckly, Stéphane, Conway Morris, Andrew, Bassetti, Matteo, Lipman, Jeffrey, Ferrer, Ricard, Qiu, Haibo, Paiva, José-Artur, Povoa, Pedro, Abidi, Khalid, Elhadi, Muhammed, Pollock, Hamish, Margetts, Ben, Young, Meredith, Bhadange, Neeraj, Tyler, Steven, Ledtischke, Anne, Finnis, Mackenzie, Dwivedi, Jyotsna, Saxena, Manoj, Biradar, Vishwanath, Soar, Natalie, Sarode, Vineet, Brewster, David, Regli, Adrian, Weeda, Elizabeth, Ahmed, Samiul, Fourie, Cheryl, Laupland, Kevin, Ramanan, Mahesh, Walsham, James, Meyer, Jason, Litton, Edward, Palermo, Anna Maria, Yap, Timothy, Eroglu, Ege, Attokaran, Antony George, Jaramillo, C'havala, Nafees, Khalid Mahmood Khan, Rashid, Nurhikmahtul Aqilah Haji Abd, Tabah, Alexi, Buetti, Niccolò, Staiquly, Quentin, Ruckly, Stéphane, Akova, Murat, Aslan, Abdullah Tarik, Leone, Marc, Conway Morris, Andrew, Bassetti, Matteo, Arvaniti, Kostoula, Lipman, Jeffrey, Ferrer, Ricard, Qiu, Haibo, Paiva, José-Artur, Povoa, Pedro, De Bus, Liesbet, De Waele, Jan, Zand, Farid, Gurjar, Mohan, Alsisi, Adel, Abidi, Khalid, Bracht, Hendrik, Hayashi, Yoshiro, Jeon, Kyeongman, Elhadi, Muhammed, Barbier, Françoi, Timsit, Jean-Françoi, EUROBACT-2 Study Group, ESICM, ESCMID ESGCIP and the OUTCOMEREA Network including, Andrea Cortegiani, and Mariachiara Ippolito

Subjects
antibiotic resistance, bloodstream infection, hospital-acquired, bacteremia, Critical Care and Intensive Care Medicine
Abstract

Purpose: In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials. Methods: We carried out a prospective international cohort study of adult patients (≥ 18years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021. Results: 2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) waspresent in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alivefrom hospital by day-28. Conclusions: HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes.

Published
2023

28. Prevalence of Vitamin D Deficiency and Associated Factors in Critically Ill Patients: A Multicenter Observational Study

Author

Chen, Kuo-Wei, primary, Chen, Chung-Wei, additional, Yuan, Kuo-Ching, additional, Wang, I-Ting, additional, Hung, Fang-Ming, additional, Wang, An-Yi, additional, Wang, Yin-Chin, additional, Kuo, Yu-Ting, additional, Lin, Yi-Che, additional, Shih, Ming-Chieh, additional, Kung, Yu-Chung, additional, Ruan, Sheng-Yuan, additional, Chiu, Ching-Tang, additional, Chao, Anne, additional, Han, Yin-Yi, additional, Kuo, Li-Kuo, additional, and Yeh, Yu-Chang, additional

Published
2021
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32. Successful Treatment of a Critically Ill COVID-19 Patient Using Continuous Renal Replacement Therapy With Enhanced Cytokine Removal and Tocilizumab: A Case Report

Author

Huang, Thomas Tao-Min, primary, Chien, Ying-Chun, additional, Wang, Chih-Hsien, additional, Chang, Sui-Yuan, additional, Wang, Jann-Tay, additional, Hsieh, Song-Chou, additional, Yeh, Yu-Chang, additional, Ku, Shih-Chi, additional, Yu, Chong-Jen, additional, Chiang, Bor-Luen, additional, Chang, Shan-Chwen, additional, and Tolwani, Ashita, additional

Published
2021
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35. Additional file 1 of Incidence and management of metabolic acidosis with sodium bicarbonate in the ICU: An international observational study

Author

Fujii, Tomoko, Udy, Andrew A., Nichol, Alistair, Bellomo, Rinaldo, Deane, Adam M., El-Khawas, Khaled, Naorungroj Thummaporn, Neto, Ary Serpa, Bergin, Hannah, Short-Burchell, Robert, Chin-Ming Chen, Kuang-Hua Cheng, Kuo-Chen Cheng, Chia, Clemente, Feng-Fan Chiang, Nai-Kuan Chou, Fazio, Timothy, Pin-Kuei Fu, Ge, Victor, Hayashi, Yoshiro, Holmes, Jennifer, Hu, Ting-Yu, Shih-Feng Huang, Iguchi, Naoya, Jones, Sarah L., Karumai, Toshiyuki, Shinshu Katayama, Ku, Shih-Chi, Chao-Lun Lai, Bor-Jen Lee, Wen-Jinn Liaw, Ong, Chelsea T. W., Paxton, Lisa, Peppin, Chloe, Roodenburg, Owen, Shinjiro Saito, Santamaria, John D., Shehabi, Yahya, Tanaka, Aiko, Ravindranath Tiruvoipati, Hsiao-En Tsai, An-Yi Wang, Wang, Chen-Yu, Yeh, Yu-Chang, Chong-Jen Yu, and Kuo-Ching Yuan

Abstract

Additional file 1. Supplementary materials include detailed methods and supplementary results as referenced inthe article.

Published
2021
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36. Microcirculatory Response to Changes in Venoarterial Extracorporeal Membrane Oxygenation Pump Flow:A Prospective Observational Study

Author

Wei, Tzu Jung, Wang, Chih Hsien, Chan, Wing Sum, Huang, Chi Hsiang, Lai, Chien Heng, Wang, Ming Jiuh, Chen, Yih Sharng, Ince, Can, Lin, Tzu Yu, Yeh, Yu Chang, Wei, Tzu Jung, Wang, Chih Hsien, Chan, Wing Sum, Huang, Chi Hsiang, Lai, Chien Heng, Wang, Ming Jiuh, Chen, Yih Sharng, Ince, Can, Lin, Tzu Yu, and Yeh, Yu Chang

Abstract

Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) pump flow is crucial for maintaining organ perfusion in patients with cardiogenic shock, but VA-ECMO pump flow optimization remains as a clinical challenge. This study aimed to investigate the response of sublingual microcirculation to changes in VA-ECMO pump flow. Methods: Sublingual microcirculation was measured before and after changing VA-ECMO pump flow according to the treatment plan of ECMO team within 24 h and at 24-48 h after VA-ECMO placement. In clinical events of increasing VA-ECMO pump flow, those events with increased perfused vessel density (PVD) were grouped into group A, and the others were grouped into group B. In clinical events of decreasing VA-ECMO pump flow, those events with increased PVD were grouped into group C, and the others were grouped into group D. Results: Increased PVD was observed in 60% (95% CI, 38.5–81.5%) of the events with increasing VA-ECMO pump flow. The probability of increasing PVD after increasing VA-ECMO pump flow were higher in the events with a PVD < 15 mm/mm2 at baseline than those with a PVD ≥ 15 mm/mm2 [100% (95% CI, 54.1–100%) vs. 42.9% (95% CI, 17.7–71.1%), P = 0.042]. Other microcirculatory and hemodynamic parameters at baseline did not differ significantly between group A and B or between group C and D. Conclusion: This study revealed contradictory and non-contradictory responses of sublingual microcirculation to changes in VA-ECMO pump flow. Tandem measurements of microcirculation before and after changing VA-ECMO pump flow may help to ensure a good microcirculation.

Published
2021

40. Preoperative Proteinuria Predicts Adverse Renal Outcomes after Coronary Artery Bypass Grafting

Author

Huang, Tao-Min, Wu, Vin-Cent, Young, Guang-Huar, Lin, Yu-Feng, Shiao, Chih-Chung, Wu, Pei-Chen, Li, Wen-Yi, Yu, Hsi-Yu, Hu, Fu-Chang, Lin, Jou-Wei, Chen, Yih-Sharng, Lin, Yen-Hung, Wang, Shoei-Shen, Hsu, Ron-Bin, Chang, Fan-Chi, Chou, Nai-Kuan, Chu, Tzong-Shinn, Yeh, Yu-Chang, Tsai, Pi-Ru, Huang, Jenq-Wen, Lin, Shuei-Liong, Chen, Yung-Ming, Ko, Wen-Je, and Wu, Kwan-Dun

Published
2011
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41. Neuroprotective Effects of Intraoperative Dexmedetomidine Infusion Combined With Goal-directed Hemodynamic Therapy for Patients Undergoing Cranial Surgery: A Double-blinded Randomized Controlled Trial

Author

Chen, Pin-Hsin, primary, Tsuang, Fon-Yih, additional, Lee, Chen-Tse, additional, Yeh, Yu-Chang, additional, Cheng, Hsiao-Liang, additional, Lee, Tzong-Shiun, additional, Chang, Ya-Wen, additional, Cheng, Ya-Jung, additional, and Wu, Chun-Yu, additional

Published
2020
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43. Contradictory responses of the microcirculation to changes in extracorporeal membrane oxygenation pump flow in patients on venoarterial extracorporeal membrane oxygenation: a prospective observational study

Author

Wei, Tzu-Jung, primary, Wang, Chih-Hsien, additional, Chan, Wing-Sum, additional, Yeh, Yi-Chun, additional, Lai, Chien-Heng, additional, Chao, Anne, additional, Huang, Chi-Hsiang, additional, Wang, Ming-Jiuh, additional, Cheng, Ya-Jung, additional, Chen, Yih-Sharng, additional, Ince, Can, additional, Lin, Tzu-Yu, additional, and Yeh, Yu-Chang, additional

Published
2020
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46. Early prediction of survival at different time intervals in sepsis patients: A visualized prediction model with nomogram and observation study.

Author

Chen, Shih-Hong, Wang, Yi-Chia, Chao, Anne, Liu, Chih-Min, Chiu, Ching-Tang, Wang, Ming-Jiuh, and Yeh, Yu-Chang

Abstract

Objectives: Sepsis is a major cause of death around the world. Complicated scoring systems require time to have data to predict short-term survival. Intensivists need a tool to predict survival in sepsis patients easily and quickly. Materials and Methods: This retrospective study reviewed the medical records of adult patients admitted to the surgical intensive care units between January 2009 and December 2011 in National Taiwan University Hospital. For this study, 739 patients were enrolled. We recorded the demographic and clinical variables of patients diagnosed with sepsis. A Cox proportional hazard model was used to analyze the survival data and determine significant risk factors to develop a prediction model. This model was used to create a nomogram for predicting the survival rate of sepsis patients up to 3 months. Results: The observed 28-day, 60-day, and 90-day survival rates were 71.43%, 52.53%, and 46.88%, respectively. The principal risk factors for survival prediction included age; history of dementia; Glasgow Coma Scale score; and lactate, creatinine, and platelet levels. Our model showed more favorable prediction than did Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment at sepsis onset (concordance index: 0.65 vs. 0.54 and 0.59). This model was used to create the nomogram for predicting the mortality at the onset of sepsis. Conclusion: We suggest that developing a nomogram with several principal risk factors can provide a quick and easy tool to early predict the survival rate at different intervals in sepsis patients. [ABSTRACT FROM AUTHOR]

Published
2022
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49. Hypoxia‐induced intestinal barrier changes in balloon‐assisted enteroscopy

Author

Lee, Tsung‐Chun, Huang, Yi‐Chen, Lu, Yen‐Zhen, Yeh, Yu‐Chang, and Yu, Linda Chia‐Hui

Subjects
Adult, Male, Mice, Inbred BALB C, Balloon Enteroscopy, Middle Aged, Research Papers, Permeability, Tight Junctions, Liver, Animals, Humans, Female, Caco-2 Cells, Intestinal Mucosa, Mitogen-Activated Protein Kinases, Hypoxia, Spleen, Aged
Abstract

KEY POINTS: Balloon‐assisted enteroscopy (BAE) is an emerging standard procedure by utilizing distensible balloons to facilitate deep endoscopy in the small and large intestine. Sporadic cases of bacteraemia were found after BAE. Balloon distension by BAE caused gut tissue hypoxia. The impact of balloon distension‐induced hypoxia on intestinal barriers remains unclear. Murine models of BAE by colonic balloon distension showed that short‐ and long‐term hypoxia evoked opposite effects on epithelial tight junctions (TJs). Short‐term hypoxia fortified TJ integrity, whereas long‐term hypoxia caused damage to barrier function. Our data showed for the first time the molecular mechanisms and signalling pathways of epithelial barrier fortification and TJ reorganization by short‐term hypoxia for the maintenance of gut homeostasis. The findings suggest avoiding prolonged balloon distension during BAE to reduce the risk of hypoxia‐induced gut barrier dysfunction. ABSTRACT: Balloon‐assisted enteroscopy (BAE) is an emerging standard procedure that uses distensible balloons to facilitate deep endoscopy. Intestines are known to harbour an abundant microflora. Whether balloon distension causes perturbation of blood flow and gut barrier dysfunction, and elicits risk of bacterial translocation remains unknown. Our aims were to (1) conduct a prospective study to gather microbiological and molecular evidence of bacterial translocation by BAE in patients, (2) establish a murine model of colonic balloon distension to investigate tissue hypoxia and intestinal barrier, and (3) assess the effect of short‐ and long‐term hypoxia on epithelial permeability using cell lines. Thirteen patients were enrolled for BAE procedures, and blood samples were obtained before and after BAE for paired comparison. Four of the 13 patients (30.8%) had positive bacterial DNA in blood after BAE. Post‐BAE endotoxaemia was higher than the pre‐BAE level. Nevertheless, no clinical symptom of sepsis or fever was reported. To mimic clinical BAE, mice were subjected to colonic balloon distension. Local tissue hypoxia was observed during balloon inflation, and reoxygenation after deflation. A trend of increased gut permeability was seen after long‐term distension, whereas a significant reduction of permeability was observed by short‐term distension in the proximal colon. Human colonic epithelial Caco‐2 cells exposed to hypoxia for 5–20 min exhibited increased tight junctional assembly, while those exposed to longer hypoxia displayed barrier disruption. In conclusion, sporadic cases of bacteraemia were found after BAE, without septic symptoms. Short‐term hypoxia by balloon distension yielded a protective effect whereas long‐term hypoxia caused damage to the gut barrier.

Published
2018

50. Improvement in Mortality and End-Stage Renal Disease in Patients With Type 2 Diabetes After Acute Kidney Injury Who Are Prescribed Dipeptidyl Peptidase-4 Inhibitors

Author

Chen, Cheng-Yi, primary, Wu, Vin-Cent, additional, Lin, Cheng-Jui, additional, Lin, Chih-Sheng, additional, Pan, Chi-Feng, additional, Chen, Han-Hsiang, additional, Lin, Yu-Feng, additional, Huang, Tao-Min, additional, Chen, Likwang, additional, Wu, Chih-Jen, additional, Lai, Tai-Shuan, additional, Tsai, I-Jung, additional, Lai, Chun-Fu, additional, Chu, Tzong-Shinn, additional, Chen, Yung-Ming, additional, Wang, Jian-Jhong, additional, Chang, Yu-Hsing, additional, Chen, Cheng-Yi, additional, Shiao, Chih-Chung, additional, Wang, Wei-Jie, additional, Lin, Jui-Hsiang, additional, Wu, Che-Hsiung, additional, Yeh, Yu-Chang, additional, Lai, Chien-Heng, additional, Tseng, Li-Jung, additional, and Wu, Kwan-Dun, additional

Published
2018
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