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4,251 results on '"Yeh, C"'

3. Robust and scalable rf spectroscopy in first-order magnetic sensitive states at second-long coherence time

Author

Yeh, C. -H., Grensemann, K. C., Dreissen, L. S., Fürst, H. A., and Mehlstäubler, T. E.

Subjects
Physics - Atomic Physics, Quantum Physics
Abstract

Trapped-ion quantum sensors have become highly sensitive tools for the search of physics beyond the Standard Model. Recently, stringent tests of local Lorentz-invariance (LLI) have been conducted with precision spectroscopy in trapped ions. We here elaborate on robust and scalable radio-frequency composite-pulse spectroscopy at second long coherence times in the magnetic sublevels of the long-lived $^{2}F_{7/2}$ state of a trapped $^{172}$Yb$^{+}$ ion. We compare two Ramsey-type composite rf pulse sequences, a generalized spin-echo (GSE) sequence and a sequence based on universal rotations with 10 rephasing pulses (UR10) that decouple the energy levels from magnetic field noise, enabling robust and accurate spectroscopy. Both sequences are characterized theoretically and experimentally in the spin-$1/2$$\ $$^{2}S_{1/2}$ electronic ground state of $^{172}$Yb$^{+}$ and results show that the UR10 sequence is 38 (13) times more robust against pulse duration (frequency detuning) errors than the GSE sequence. We extend our simulations to the eight-level manifold of the $^2F_{7/2}$ state, which is highly sensitive to a possible violation of LLI, and show that the UR10 sequence can be used for high-fidelity Ramsey spectroscopy in noisy environments. The UR10 sequence is implemented experimentally in the $^2F_{7/2}$ manifold and a coherent signal of up to $2.5\,$s is reached. We have implemented the sequence and used it to perform the most stringent test of LLI in the electron-photon sector to date. Due to the robustness of the UR10 sequence, it can be applied on larger ion crystals to improve tests of Lorentz symmetry further. We demonstrate that the sequence can also be used to extract the quadrupole moment of the meta-stable $^{2}F_{7/2}$ state, obtaining a value of $\Theta\,=\,-0.0298(38)\,ea^{2}_{0}$ which is in agreement with the value deduced from clock measurements., Comment: 19 pages, 7 figures

Published
2023
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4. Variable Electrical Responses in Epitaxial Graphene Nanoribbons

Author

Yeh, C. -C., Mhatre, S. M., Tran, N. T. M., Hill, H. M., Jin, H., Liao, P. -C., Patel, D. K., Elmquist, R. E., Liang, C. -T., and Rigosi, A. F.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

We have demonstrated the fabrication of both armchair and zigzag epitaxial graphene nanoribbon (GNR) devices on 4H-SiC using a polymer-assisted sublimation growth method. The phenomenon of terrace step formation has traditionally introduced the risk of GNR deformation along sidewalls, but a polymer-assisted sublimation method helps mitigate this risk. Each type of 50 nm wide GNR is examined electrically and optically (armchair and zigzag), with the latter method being a check on the quality of the GNR devices and the former using alternating current to investigate resistance attenuation from frequencies above 100 Hz. Rates of attenuation are determined for each type of GNR device, revealing subtle suggested differences between armchair and zigzag GNRs.

Published
2023

6. Performance of the CMS High Granularity Calorimeter prototype to charged pion beams of 20$-$300 GeV/c

Author

Acar, B., Adamov, G., Adloff, C., Afanasiev, S., Akchurin, N., Akgün, B., Alhusseini, M., Alison, J., de Almeida, J. P. Figueiredo de sa Sousa, de Almeida, P. G. Dias, Alpana, A., Alyari, M., Andreev, I., Aras, U., Aspell, P., Atakisi, I. O., Bach, O., Baden, A., Bakas, G., Bakshi, A., Banerjee, S., DeBarbaro, P., Bargassa, P., Barney, D., Beaudette, F., Beaujean, F., Becheva, E., Becker, A., Behera, P., Belloni, A., Bergauer, T., Berni, M. El, Besancon, M., Bhattacharya, S., Bhowmik, D., Bilki, B., Bilokin, S., Blazey, G. C., Blekman, F., Bloch, P., Bodek, A., Bonanomi, M., Bonis, J., Bonnemaison, A., Bonomally, S., Borg, J., Bouyjou, F., Bower, N., Braga, D., Brennan, L., Brianne, E., Brondolin, E., Bryant, P., Buhmann, E., Buhmann, P., Butler-Nalin, A., Bychkova, O., Callier, S., Calvet, D., Canderan, K., Cankocak, K., Cao, X., Cappati, A., Caraway, B., Caregari, S., Carty, C., Cauchois, A., Ceard, L., Cerci, D. S., Cerci, S., Cerminara, G., Chadeeva, M., Charitonidis, N., Chatterjee, R., Chen, J. A., Chen, Y. M., Cheng, H. J., Cheng, K. Y., Cheung, H., Chokheli, D., Cipriani, M., Čoko, D., Couderc, F., Cuba, E., Danilov, M., Dannheim, D., Daoud, W., Das, I., Dauncey, P., Davies, G., Davignon, O., Day, E., Debbins, P., Defranchis, M. M., Delagnes, E., Demiragli, Z., Demirbas, U., Derylo, G., Diaz, D., Diehl, L., Dinaucourt, P., Dincer, G. G., Dittmann, J., Dragicevic, M., Dugad, S., Dulucq, F., Dumanoglu, I., Dünser, M., Dutta, S., Dutta, V., Edberg, T. K., Elias, F., Emberger, L., Eno, S. C., Ershov, Yu., Extier, S., Fahim, F., Fallon, C., Fard, K. Sarbandi, Fedi, G., Ferragina, L., Forthomme, L., Frahm, E., Franzoni, G., Freeman, J., French, T., Gadow, K., Gandhi, P., Ganjour, S., Gao, X., Garcia, M. T. Ramos, Garcia-Bellido, A., Garutti, E., Gastaldi, F., Gastler, D., Gecse, Z., Germer, A., Gerwig, H., Gevin, O., Ghosh, S., Gilbert, A., Gilbert, W., Gill, K., Gingu, C., Gninenko, S., Golunov, A., Golutvin, I., Gonultas, B., Gorbounov, N., Göttlicher, P., Gouskos, L., Graf, C., Gray, A. B., Grieco, C., Gr\"önroos, S., Gu, Y., Guilloux, F., Guler, E. Gurpinar, Guler, Y., Gülmez, E., Guo, J., Gutti, H., Hakimi, A., Hammer, M., Hartbrich, O., Hassanshahi, H. M., Hatakeyama, K., Hazen, E., Heering, A., Hegde, V., Heintz, U., Heuchel, D., Hinton, N., Hirschauer, J., Hoff, J., Hou, W. S., Hou, X., Hua, H., Huck, S., Hussain, A., Incandela, J., Irles, A., Irshad, A., Isik, C., Jain, S., Jaroslavceva, J., Jheng, H. R., Joshi, U., Kaadze, K., Kachanov, V., Kalipoliti, L., Kaminskiy, A., Kanuganti, A. R., Kao, Y. W., Kapoor, A., Kara, O., Karneyeu, A., Kałuzińska, O., Kaya, M., Kaya, O., Kazhykharim, Y., Khan, F. A., Khukhunaishvili, A., Kieseler, J., Kilpatrick, M., Kim, S., Koetz, K., Kolberg, T., Komm, M., Köseyan, O. K., Kraus, V., Krawczyk, M., Kristiansen, K., Kristić, A., Krohn, M., Kronheim, B., Krüger, K., Kulis, S., Kumar, M., Kunori, S., Kuo, C. M., Kuryatkov, V., Kvasnicka, J., Kyre, S., Lai, Y., Lamichhane, K., Landsberg, G., Lange, C., Langford, J., Laurien, S., Lee, M. Y., Lee, S. W., Leiton, A. G. Stahl, Levin, A., Li, A., Li, J. H., Li, Y. Y., Liang, Z., Liao, H., Lin, Z., Lincoln, D., Linssen, L., Lipton, R., Liu, G., Liu, Y., Lobanov, A., Lohezic, V., Lomidze, D., Lu, R. S., Lu, S., Lupi, M., Lysova, I., Magnan, A. -M., Magniette, F., Mahjoub, A., Martens, S., Matysek, M., Meier, B., Malakhov, A., Mallios, S., Mandjavize, I., Mannelli, M., Mans, J., Marchioro, A., Martelli, A., Martinez, G., Masterson, P., Matthewman, M., Mayekar, S. N., David, A., Coco, S., Meng, B., Menkel, A ., Mestvirishvili, A., Milella, G., Mirza, I., Moccia, S., Mohanty, G. B., Monti, F., Moortgat, F. W., Morrissey, I., Motta, J., Murthy, S., Musić, J., Musienko, Y., Nabili, S., Nguyen, M., Nikitenko, A., Noonan, D., Noy, M., Nurdan, K., Nursanto, M. Wulansatiti, Ochando, C., Odell, N., Okawa, H., Onel, Y., Ortez, W., Ozegović, J., Ozkorucuklu, S., Paganis, E., Palmer, C. A., Pandey, S., Pantaleo, F., Papageorgakis, C., Papakrivopoulos, I., Paranjpe, M., Parshook, J., Pastika, N., Paulini, M., Peitzmann, T., Peltola, T., Peng, N., Perraguin, A. Buchot, Petiot, P., Pierre-Emile, T., Pinto, M. Vicente Barreto, Popova, E., Pöschl, R., Prosper, H., Prvan, M., Puljak, I., Qasim, S. R., Qu, H., Quast, T., Quinn, R., Quinnan, M., Rane, A., Rao, K. K., Rapacz, K., Raux, L., Redjeb, W., Reinecke, M., Revering, M., Richard, F., Roberts, A., Sanchez, A. M., Rohlf, J., Rolph, J., Romanteau, T., Rosado, M., Rose, A., Rovere, M., Roy, A., Rubinov, P., Rusack, R., Rusinov, V., Ryjov, V., Sahin, O. M., Salerno, R., Saradhy, R., Sarkar, T., Sarkisla, M. A., Sauvan, J. B., Schmidt, I., Schmitt, M., Schuwalow, S., Scott, E., Seez, C., Sefkow, F., Selivanova, D., Sharma, S., Shelake, M., Shenai, A., Shukla, R., Sicking, E., De, M., Silva, P., Simkina, P., Simon, F., Simsek, A. E., Sirois, Y., Smirnov, V., Sobering, T. J., Spencer, E., Srimanobhas, N., Steen, A., Strait, J., Strobbe, N., Su, X. F., Sudo, Y., Suarez, C. Mantilla, Sukhov, E., Sulak, L., Sun, L., Suryadevara, P., Syal, C., de La Taille, C., Tali, B., Tan, C. L., Tao, J., Tarabini, A., Tatli, T., Thaus, R., Taylor, R. D., Tekten, S., Thiebault, A., Thienpont, D., Tiley, C., Tiras, E., Titov, M., Tlisov, D., Tok, U. G., Kayis, A., Troska, J., Tsai, L. S., Tsamalaidze, Z., Tsipolitis, G., Tsirou, A., Undleeb, S., Urbanski, D., Uslan, E., Ustinov, V., Uzunian, A., Varela, J., Velasco, M., Vernazza, E., Viazlo, O., Vichoudis, P., Virdee, T., Voirin, E., Vojinovi\c, M., Vojinovic, M., Wade, A., Wang, C., Wang, C. C., Wang, D., Wang, F., Wang, X., Wang, Z., Wayne, M., Webb, S. N., Whitbeck, A., Wickwire, R., Wilson, J. S., Wu, H. Y., Wu, L., Xiao, M., Yang, J., Yeh, C. H, Yohay, R., Yu, D., Yu, S. S., Yuan, C., Miao, Y., Yumiceva, F., Yusuff, I., Zabi, A., Zacharopoulou, A., Zamiatin, N., Zarubin, A., Zehetner, P., Zerwas, D., Zhang, H., Zhang, J., Zhang, Y., Zhang, Z., and Zhao, X.

Subjects
Physics - Instrumentation and Detectors
Abstract

The upgrade of the CMS experiment for the high luminosity operation of the LHC comprises the replacement of the current endcap calorimeter by a high granularity sampling calorimeter (HGCAL). The electromagnetic section of the HGCAL is based on silicon sensors interspersed between lead and copper (or copper tungsten) absorbers. The hadronic section uses layers of stainless steel as an absorbing medium and silicon sensors as an active medium in the regions of high radiation exposure, and scintillator tiles directly readout by silicon photomultipliers in the remaining regions. As part of the development of the detector and its readout electronic components, a section of a silicon-based HGCAL prototype detector along with a section of the CALICE AHCAL prototype was exposed to muons, electrons and charged pions in beam test experiments at the H2 beamline at the CERN SPS in October 2018. The AHCAL uses the same technology as foreseen for the HGCAL but with much finer longitudinal segmentation. The performance of the calorimeters in terms of energy response and resolution, longitudinal and transverse shower profiles is studied using negatively charged pions, and is compared to GEANT4 predictions. This is the first report summarizing results of hadronic showers measured by the HGCAL prototype using beam test data., Comment: Accepted for publication by JINST

Published
2022

7. Report of the Topical Group on Physics Beyond the Standard Model at Energy Frontier for Snowmass 2021

Author

Bose, Tulika, Boveia, Antonio, Doglioni, Caterina, Griso, Simone Pagan, Hirschauer, James, Lipeles, Elliot, Liu, Zhen, Shah, Nausheen R., Wang, Lian-Tao, Agashe, Kaustubh, Alimena, Juliette, Baum, Sebastian, Berkat, Mohamed, Black, Kevin, Gardner, Gwen, Gherghetta, Tony, Greaves, Josh, Haehn, Maxx, Harris, Phil C., Harris, Robert, Hogan, Julie, Jayawardana, Suneth, Kahn, Abraham, Kalinowski, Jan, Knapen, Simon, Lewis, Ian M., Narain, Meenakshi, Pachal, Katherine, Reece, Matthew, Reina, Laura, Robens, Tania, Tricoli, Alessandro, Wagner, Carlos E. M., Xu, Riley, Yu, Felix, Zarnecki, Filip, Aboubrahim, Amin, Albert, Andreas, Albrow, Michael, Altmannshofer, Wolfgang, Andonian, Gerard, Apresyan, Artur, Assamagan, Kétévi Adikle, Azzi, Patrizia, Baer, Howard, Baker, Michael J., Banerjee, Avik, Barger, Vernon, Batell, Brian, Bauer, Martin, Beauchesne, Hugues, Bein, Samuel, Belyaev, Alexander, Beniwal, Ankit, Berggren, Mikael, Bhattiprolu, Prudhvi N., Blinov, Nikita, Blondel, Alain, Brandt, Oleg, Cacciapaglia, Giacomo, Capdevilla, Rodolfo, Carena, Marcela, Cazzaniga, Cesare, Celiberto, Francesco Giovanni, Cesarotti, Cari, Chekanov, Sergei V., Cheng, Hsin-Chia, Chen, Thomas Y., Chen, Yuze, Chivukula, R. Sekhar, Citron, Matthew, Cline, James, Cohen, Tim, Collins, Jack H., Corrigan, Eric, Craig, Nathaniel, Craik, Daniel, Crivellin, Andreas, Curtin, David, Darmora, Smita, Das, Arindam, Dasu, Sridhara, de Cosa, Annapaola, Deandrea, Aldo, Delgado, Antonio, Demiragli, Zeynep, d'Enterria, David, Deppisch, Frank F., Dermisek, Radovan, Desai, Nishita, Deshpande, Abhay, de Vries, Jordy, Dickinson, Jennet, Dienes, Keith R., Di Petrillo, Karri Folan, Dolan, Matthew J., Dong, Peter, Draper, Patrick, Drewes, Marco, Dreyer, Etienne, Du, Peizhi, Eble, Florian, Ekhterachian, Majid, Endo, Motoi, Essig, Rouven, Farr, Jesse N., Fassi, Farida, Feng, Jonathan L., Ferretti, Gabriele, Filipetto, Daniele, Flacke, Thomas, Franceschini, Roberto, Franzosi, Diogo Buarque, Fujii, Keisuke, Fuks, Benjamin, Gadam, Sri Aditya, Gao, Boyu, Garcia-Bellido, Aran, Garcia, Isabel Garcia, Garzelli, Maria Vittoria, Gedney, Stephen, Genest, Marie-Hélène, Ghosh, Tathagata, Golkowski, Mark, di Cortona, Giovanni Grilli, Guler, Emine Gurpinar, Guler, Yalcin, Guo, C., Graf, Nate, Haisch, Ulrich, Hajer, Jan, Hamaguchi, Koichi, Han, Tao, Harris, Philip, Heinemeyer, Sven, Hill, Christopher S., Hiltbrand, Joshua, Holmes, Tova Ray, Homiller, Samuel, Hong, Sungwoo, Hopkins, Walter, Hsu, Shih-Chieh, Ilten, Phil, Islam, Wasikul, Iwamoto, Sho, Jeans, Daniel, Jeanty, Laura, Jia, Haoyi, Jindariani, Sergo, Johnson, Daniel, Kahlhoefer, Felix, Kahn, Yonatan, Karchin, Paul, Katsouleas, Thomas, Kawada, Shin-ichi, Kawamura, Junichiro, Kelso, Chris, Khoda, Elham E, Khoze, Valery, Kim, Doojin, Kitahara, Teppei, Klaric, Juraj, Klasen, Michael, Kong, Kyoungchul, Kotlarski, Wojciech, Kotwal, Ashutosh V., Kozaczuk, Jonathan, Kriske, Richard, Kulkarni, Suchita, Kumar, Jason, Kunkel, Manuel, Landsberg, Greg, Lane, Kenneth, Lange, Clemens, Lee, Lawrence, Liao, Jiajun, Lillard, Benjamin, Li, Lingfeng, Li, Shuailong, Li, Shu, List, Jenny, Li, Tong, Liu, Hongkai, Liu, Jia, Long, Jonathan D, Lunghi, Enrico, Lyu, Kun-Feng, Marfatia, Danny, Martinez, Dakotah, Martin, Stephen P., McGinnis, Navin, McGinty, Karrick, Mękała, Krzysztof, Meloni, Federico, Mikulenko, Oleksii, Huang, Ming, Mishra, Rashmish K., Mitra, Manimala, Mitsou, Vasiliki A., Moon, Chang-Seong, Moreno, Alexander, Moroi, Takeo, Mourou, Gerard, Mrowietz, Malte, Muggli, Patric, Nakajima, Jurina, Nath, Pran, Nelson, J., Neubert, Matthias, Nosler, Laura, de Vera, Maria Teresa Núñez Pardo, Okada, Nobuchika, Okada, Satomi, Okorokov, Vitalii A., Onel, Yasar, Ou, Tong, Ovchynnikov, Maksym, Padhan, Rojalin, Pani, Priscilla, Panizzi, Luca, Papaefstathiou, Andreas, Pedro, Kevin, Peña, Cristián, Piazza, Federica, Pinfold, James, Pinna, Deborah, Porod, Werner, Potter, Chris, Prim, Markus Tobias, Profumo, Stefano, Proudfoot, James, Rai, Mudit, Rajec, Filip, Ramos, Reese, Ramsey-Musolf, Michael J., Resta-Lopez, Javier, Reuter, Jürgen, Ringwald, Andreas, Rizzi, Chiara, Rizzo, Thomas G., Rossi, Giancarlo, Ruiz, Richard, Rygaard, L., Sahai, Aakash A., Salam, Shadman, Sandick, Pearl, Sathyan, Deepak, Scherb, Christiane, Schwaller, Pedro, Schwarze, Leonard, Scott, Pat, Sekmen, Sezen, Sengupta, Dibyashree, Sen, S., Sfyrla, Anna, Shackelford, Eric, Sharma, T., Sharma, Varun, Shelton, Jessie, Shepherd, William, Shin, Seodong, Simmons, Elizabeth H., Sloneker, Zoie, Sierra, Carlos Vázquez, Sjöstrand, Torbjörn, Snyder, Scott, Song, Huayang, Stark, Giordon, Stengel, Patrick, Stohr, Joachim, Stolarski, Daniel, Strassler, Matt, Strobbe, Nadja, Gonski, Julia, Suarez, Rebeca Gonzalez, Suehara, Taikan, Su, Shufang, Su, Wei, Syed, Raza M., Tait, Tim M. P., Tajima, Toshiki, Tang, Andy, Tata, Xerxes, Tchalokov, Teodor, Thamm, Andrea, Thomas, Brooks, Toro, Natalia, Tran, Nhan V., Truong, Loan, Tsai, Yu-Dai, Tuecke, Eva, Venkatasubramanian, Nikhilesh, Verhaaren, Chris B., Vuosalo, Carl, Wang, Xiao-Ping, Wang, Xing, Wang, Yikun, Wang, Zhen, Weber, Christian, White, Glen, White, Martin, Williams, Anthony G., Williams, Brady, Williams, Mike, Willocq, Stephane, Woodcock, Alex, Wu, Yongcheng, Xie, Ke-Pan, Xie, Keping, Xie, Si, Yeh, C. -H., Yonamine, Ryo, Yu, David, Yu, S. -S., Zaazoua, Mohamed, Żarnecki, Aleksander Filip, Zembaczynski, Kamil, Zhang, Danyi, Zhang, Jinlong, Zimmermann, Frank, and Zurita, Jose

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

This is the Snowmass2021 Energy Frontier (EF) Beyond the Standard Model (BSM) report. It combines the EF topical group reports of EF08 (Model-specific explorations), EF09 (More general explorations), and EF10 (Dark Matter at Colliders). The report includes a general introduction to BSM motivations and the comparative prospects for proposed future experiments for a broad range of potential BSM models and signatures, including compositeness, SUSY, leptoquarks, more general new bosons and fermions, long-lived particles, dark matter, charged-lepton flavor violation, and anomaly detection., Comment: 108 pages + 38 pages references and appendix, 37 figures, Report of the Topical Group on Beyond the Standard Model Physics at Energy Frontier for Snowmass 2021. The first nine authors are the Conveners, with Contributions from the other authors

Published
2022

8. Constraints on Sub-GeV Dark Matter--Electron Scattering from the CDEX-10 Experiment

Author

Zhang, Z. Y., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yeh, C. H., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract

We present improved germanium-based constraints on sub-GeV dark matter via dark matter--electron ($\chi$-$e$) scattering using the 205.4 kg$\cdot$day dataset from the CDEX-10 experiment. Using a novel calculation technique, we attain predicted $\chi$-$e$ scattering spectra observable in high-purity germanium detectors. In the heavy mediator scenario, our results achieve 3 orders of magnitude of improvement for $m_{\chi}$ larger than 80 MeV/c$^2$ compared to previous germanium-based $\chi$-$e$ results. We also present the most stringent $\chi$-$e$ cross-section limit to date among experiments using solid-state detectors for $m_{\chi}$ larger than 90 MeV/c$^2$ with heavy mediators and $m_{\chi}$ larger than 100 MeV/c$^2$ with electric dipole coupling. The result proves the feasibility and demonstrates the vast potential of a new $\chi$-$e$ detection method with high-purity germanium detectors in ultralow radioactive background., Comment: 6 pages, 3 figures. Version updated to match PRL version

Published
2022
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9. Search for Neutrinoless Double-Beta Decay of $^{76}$Ge with a Natural Broad Energy Germanium Detector

Author

CDEX collaboration, Dai, W. H., Ma, H., Yue, Q., She, Z., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, Y. H., Cheng, J. P., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yang, L. T., Yeh, C. H., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

A natural broad energy germanium (BEGe) detector is operated in the China Jinping Underground Laboratory (CJPL) for a feasibility study of building the next generation experiment of the neutrinoless double-beta (0{$\nu\beta\beta$}) decay of $^{76}$Ge. The setup of the prototype facility, characteristics of the BEGe detector, background reduction methods, and data analysis are described in this paper. A background index of 6.4$\times$10$^{-3}$ counts/(keV$\cdot$kg$\cdot$day) is achieved and 1.86 times lower than our previous result of the CDEX-1 detector. No signal is observed with an exposure of 186.4 kg$\cdot$day, thus a limit on the half life of $^{76}$Ge 0$\nu\beta\beta$ decay is set at T$_{1/2}^{0\nu}$ $>$ 5.62$\times$10$^{22}$ yr at 90% C.L.. The limit corresponds to an effective Majorana neutrino mass in the range of 4.6 $\sim$ 10.3 eV, dependent on the nuclear matrix elements., Comment: 10 pages, 15 figures

Published
2022
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10. Precision timing for collider-experiment-based calorimetry

Author

Chekanov, S. V., Simon, F., Boudry, V., Chung, W., Gorham, P. W., Nguyen, M., Tully, C. G., Eno, S. C., Lai, Y., Kotwal, A. V., Ko, S., Laktineh, I., Lee, S., Lee, J. S. H., Lucchini, M. T., Prechelt, R., Yoo, H., Yeh, C. -H, Yu, S. -S., Varner, G. S., and Zhu, R.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

In this White Paper for the 2021 Snowmass process, we discuss aspects of precision timing within electromagnetic and hadronic calorimeter systems for high-energy physics collider experiments. Areas of applications include particle identification, event and object reconstruction, and pileup mitigation. Two different system options are considered, namely cell-level timing capabilities covering the full detector volume, and dedicated timing layers integrated in calorimeter systems. A selection of technologies for the different approaches is also discussed., Comment: 22 pages, 9 figures, Editors: S. V. Chekanov, F. Simon. Submitted to the Proceedings of the US Community Study on the Future of Particle Physics (Snowmass 2021)

Published
2022

11. Constraints on sub-GeV dark matter boosted by cosmic rays from the CDEX-10 experiment at the China Jinping Underground Laboratory

Author

Xu, R., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, X. Y., Guo, Q. J., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y., Liu, Y. D., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, Y., Xue, T., Yan, Y. L., Yeh, C. H., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract

We present new constraints on light dark matter boosted by cosmic rays (CRDM) using the 205.4 kg day data of the CDEX-10 experiment conducted at the China Jinping Underground Laboratory. The Monte Carlo simulation package CJPL\_ESS was employed to evaluate the Earth shielding effect. Several key factors have been introduced and discussed in our CRDM analysis, including the contributions from heavier CR nuclei than proton and helium, the inhomogeneity of CR distribution, and the impact of the form factor in the Earth attenuation calculation. Our result excludes the dark matter--nucleon elastic scattering cross-section region from $1.7\times 10^{-30}$ to $10^{-26}~\rm cm^2$ for dark matter of 10 keV$/c^2$ to 1 GeV$/c^2$., Comment: 9 pages, 7 figures. Version updated to match PRD version

Published
2022
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12. Studies of the Earth shielding effect to direct dark matter searches at the China Jinping Underground Laboratory

Author

Liu, Z. Z., Yang, L. T., Yue, Q., Yeh, C. H., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, J. H., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, X. Y., Guo, Q. J., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, R. M. J., Li, X. Q., Li, Y. L., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y., Liu, Y. D., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wang, Z., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract

Dark matter direct detection experiments mostly operate at deep underground laboratories. It is necessary to consider shielding effect of the Earth, especially for dark matter particles interacting with a large cross section. We analyzed and simulated the Earth shielding effect for dark matter at the China Jinping Underground Laboratory (CJPL) with a simulation package, CJPL Earth Shielding Simulation code (CJPL\_ESS), which is applicable to other underground locations. The further constraints on the $\chi$-N cross section exclusion regions are derived based on the studies with CDEX experiment data., Comment: 8 pages, 8 figures, 2 tables. Version updated to match PRD version

Published
2021
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13. Response of a CMS HGCAL silicon-pad electromagnetic calorimeter prototype to 20-300 GeV positrons

Author

Acar, B., Adamov, G., Adloff, C., Afanasiev, S., Akchurin, N., Akgün, B., Khan, F. Alam, Alhusseini, M., Alison, J., Alpana, A., Altopp, G., Alyari, M., An, S., Anagul, S., Andreev, I., Aspell, P., Atakisi, I. O., Bach, O., Baden, A., Bakas, G., Bakshi, A., Bannerjee, S., Bargassa, P., Barney, D., Beaudette, F., Beaujean, F., Becheva, E., Becker, A., Behera, P., Belloni, A., Bergauer, T., Besancon, M., Bhattacharya, S., Bhowmik, D., Bilki, B., Bloch, P., Bodek, A., Bonanomi, M., Bonnemaison, A., Bonomally, S., Borg, J., Bouyjou, F., Bower, N., Braga, D., Brashear, J., Brondolin, E., Bryant, P., Perraguin, A. Buchot, Bueghly, J., Burkle, B., Butler-Nalin, A., Bychkova, O., Callier, S., Calvet, D., Cao, X., Cappati, A., Caraway, B., Caregari, S., Cauchois, A., Ceard, L., Cekmecelioglu, Y. C., Cerci, S., Cerminara, G., Chadeeva, M., Charitonidis, N., Chatterjee, R., Chen, Y. M., Chen, Z., Cheng, H. J., Cheng, K. y., Chernichenko, S., Cheung, H., Chien, C. H., Choudhury, S., Čoko, D., Collura, G., Couderc, F., Danilov, M., Dannheim, D., Daoud, W., Dauncey, P., David, A., Davies, G., Davignon, O., Day, E., DeBarbaro, P., De Guio, F., de La Taille, C., De Silva, M., Debbins, P., Defranchis, M. M., Delagnes, E., Berrio, J. M. Deltoro, Derylo, G., de Almeida, P. G. Dias, Diaz, D., Dinaucourt, P., Dittmann, J., Dragicevic, M., Dugad, S., Dulucq, F., Dumanoglu, I., Dutta, V., Dutta, S., Dünser, M., Eckdahl, J., Edberg, T. K., Berni, M. El, Elias, F., Eno, S. C., Ershov, Yu., Everaerts, P., Extier, S., Fahim, F., Fallon, C., Fedi, G., Alves, B. A. Fontana Santos, Frahm, E., Franzoni, G., Freeman, J., French, T., Gandhi, P., Ganjour, S., Gao, X., Garcia-Bellido, A., Gastaldi, F., Gecse, Z., Geerebaert, Y., Gerwig, H., Gevin, O., Ghosh, S., Gilbert, A., Gilbert, W., Gill, K., Gingu, C., Gninenko, S., Golunov, A., Golutvin, I., Gonzalez, T., Gorbounov, N., Gouskos, L., Gray, A. B., Gu, Y., Guilloux, F., Guler, Y., Gülmez, E., Guo, J., Guler, E. Gurpinar, Hammer, M., Hassanshahi, H. M., Hatakeyama, K., Heering, A., Hegde, V., Heintz, U., Hinton, N., Hirschauer, J., Hoff, J., Hou, W. -S., Hou, X., Hua, H., Incandela, J., Irshad, A., Isik, C., Jain, S., Jheng, H. R., Joshi, U., Kachanov, V., Kalinin, A., Kalipoliti, L., Kaminskiy, A., Kapoor, A., Kara, O., Karneyeu, A., Kaya, M., Kaya, O., Topaksu, A. Kayis, Khukhunaishvili, A., Kiesler, J., Kilpatrick, M., Kim, S., Koetz, K., Kolberg, T., Köseyan, O. K., Kristić, A., Krohn, M., Krüger, K., Kulagin, N., Kulis, S., Kunori, S., Kuo, C. M., Kuryatkov, V., Kyre, S., Lai, Y., Lamichhane, K., Landsberg, G., Lange, C., Langford, J., Lee, M. Y., Levin, A., Li, A., Li, B., Li, J. H., Li, Y. y., Liao, H., Lincoln, D., Linssen, L., Lipton, R., Liu, Y., Lobanov, A., Lu, R. -S., Lupi, M., Lysova, I., Magnan, A. -M., Magniette, F., Mahjoub, A., Maier, A. A., Malakhov, A., Mallios, S., Mandjavize, I., Mannelli, M., Mans, J., Marchioro, A., Martelli, A., Martinez, G., Masterson, P., Meng, B., Mengke, T., Mestvirishvili, A., Mirza, I., Moccia, S., Mohanty, G. B., Monti, F., Morrissey, I., Murthy, S., Musić, J., Musienko, Y., Nabili, S., Nagar, A., Nguyen, M., Nikitenko, A., Noonan, D., Noy, M., Nurdan, K., Ochando, C., Odegard, B., Odell, N., Okawa, H., Onel, Y., Ortez, W., Ozegović, J., Ozkorucuklu, S., Paganis, E., Pagenkopf, D., Palladino, V., Pandey, S., Pantaleo, F., Papageorgakis, C., Papakrivopoulos, I., Parshook, J., Pastika, N., Paulini, M., Paulitsch, P., Peltola, T., Gomes, R. Pereira, Perkins, H., Petiot, P., Pierre-Emile, T., Pitters, F., Popova, E., Prosper, H., Prvan, M., Puljak, I., Qu, H., Quast, T., Quinn, R., Quinnan, M., Garcia, M. T. Ramos, Rao, K. K., Rapacz, K., Raux, L., Reichenbach, G., Reinecke, M., Revering, M., Roberts, A., Romanteau, T., Rose, A., Rovere, M., Roy, A., Rubinov, P., Rusack, R., Rusinov, V., Ryjov, V., Sahin, O. M., Salerno, R., Rodriguez, A. M. Sanchez, Saradhy, R., Sarkar, T., Sarkisla, M. A., Sauvan, J. B., Schmidt, I., Schmitt, M., Scott, E., Seez, C., Sefkow, F., Sharma, S., Shein, I., Shenai, A., Shukla, R., Sicking, E., Sieberer, P., Silva, P., Simsek, A. E., Sirois, Y., Smirnov, V., Sozbilir, U., Spencer, E., Steen, A., Strait, J., Strobbe, N., Su, J. W., Sukhov, E., Sun, L., Cerci, D. Sunar, Syal, C., Tali, B., Tan, C. L., Tao, J., Tastan, I., Tatli, T., Thaus, R., Tekten, S., Thienpont, D., Tiras, E., Titov, M., Tlisov, D., Tok, U. G., Troska, J., Tsai, L. -S., Tsamalaidze, Z., Tsipolitis, G., Tsirou, A., Tyurin, N., Undleeb, S., Urbanski, D., Ustinov, V., Uzunian, A., Van de Klundert, M., Varela, J., Velasco, M., Viazlo, O., Pinto, M. Vicente Barreto, Virdee, P. Vichoudis T., de Oliveira, R. Vizinho, Voelker, J., Voirin, E., Vojinovic, M., Wade, A., Wang, C., Wang, F., Wang, X., Wang, Z., Wayne, M., Webb, S. N., Whitbeck, A., White, D., Wickwire, R., Wilson, J. S., Winter, D., Wu, H. y., Wu, L., Nursanto, M. Wulansatiti, Yeh, C. H, Yohay, R., Yu, D., Yu, G. B., Yu, S. S., Yuan, C., Yumiceva, F., Yusuff, I., Zacharopoulou, A., Zamiatin, N., Zarubin, A., Zenz, S., Zghiche, A., Zhang, H., Zhang, J., Zhang, Y., and Zhang, Z.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The Compact Muon Solenoid Collaboration is designing a new high-granularity endcap calorimeter, HGCAL, to be installed later this decade. As part of this development work, a prototype system was built, with an electromagnetic section consisting of 14 double-sided structures, providing 28 sampling layers. Each sampling layer has an hexagonal module, where a multipad large-area silicon sensor is glued between an electronics circuit board and a metal baseplate. The sensor pads of approximately 1 cm$^2$ are wire-bonded to the circuit board and are readout by custom integrated circuits. The prototype was extensively tested with beams at CERN's Super Proton Synchrotron in 2018. Based on the data collected with beams of positrons, with energies ranging from 20 to 300 GeV, measurements of the energy resolution and linearity, the position and angular resolutions, and the shower shapes are presented and compared to a detailed Geant4 simulation.

Published
2021
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14. Motional heating of spatially extended ion crystals

Author

Kalincev, D., Dreissen, L. S., Kulosa, A. P., Yeh, C-H., Fürst, H. A., and Mehlstäubler, T. E.

Subjects
Physics - Atomic Physics, Quantum Physics
Abstract

We study heating of motional modes of a single ion and of extended ion crystals trapped in a linear radio frequency (rf) Paul trap with a precision of $\Delta \dot{\bar{n}} \approx 0.2 $ phonons s$^{-1}$. Single-ion axial and radial heating rates are consistent and electric field noise has been stable over the course of four years. At a secular frequency of $\omega_\mathrm{sec}=2\pi\times620$ kHz, we measure $\dot{\bar{n}} = 0.56(6)$ phonons s$^{-1}$ per ion for the center-of-mass (com) mode of linear chains of up to eleven ions and observe no significant heating of the out-of-phase (oop) modes. By displacing the ions away from the nodal line, inducing excess micromotion, rf noise heats the com mode quadratically as a function of radial displacement $r$ by $\dot{\bar{n}}(r)/ r^2 = 0.89(4)$ phonons s$^{-1}$ $\mu$m$^{-2}$ per ion, while the oop modes are protected from rf-noise induced heating in linear chains. By changing the quality factor of the resonant rf circuit from $Q=542$ to $Q=204$, we observe an increase of rf noise by a factor of up to 3. We show that the rf-noise induced heating of motional modes of extended crystals also depends on the symmetry of the crystal and of the mode itself. As an example, we consider several 2D and 3D crystal configurations. Heating rates of up to 500 phonons s$^{-1}$ are observed for individual modes, giving rise to a total kinetic energy increase and thus a fractional time dilation shift of up to $-0.3\times 10^{-18}$ s$^{-1}$ of the total system. In addition, we detail on how the excitation probability of the individual ions is reduced and decoherence is increased due to the Debye-Waller effect.

Published
2020
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15. Construction and commissioning of CMS CE prototype silicon modules

Author

Acar, B., Adamov, G., Adloff, C., Afanasiev, S., Akchurin, N., Akgün, B., Alhusseini, M., Alison, J., Altopp, G., Alyari, M., An, S., Anagul, S., Andreev, I., Andrews, M., Aspell, P., Atakisi, I. A., Bach, O., Baden, A., Bakas, G., Bakshi, A., Bargassa, P., Barney, D., Becheva, E., Behera, P., Belloni, A., Bergauer, T., Besancon, M., Bhattacharya, S., Bhowmik, D., Bloch, P., Bodek, A., Bonanomi, M., Bonnemaison, A., Bonomally, S., Borg, J., Bouyjou, F., Braga, D., Brashear, J., Brondolin, E., Bryant, P., Bueghly, J., Bilki, B., Burkle, B., Butler-Nalin, A., Callier, S., Calvet, D., Cao, X., Caraway, B., Caregari, S., Ceard, L., Cekmecelioglu, Y. C., Cerminara, G., Charitonidis, N., Chatterjee, R., Chen, Y. M., Chen, Z., Cheng, K. y., Chernichenko, S., Cheung, H., Chien, C. H., Choudhury, S., Čoko, D., Collura, G., Couderc, F., Dumanoglu, I., Dannheim, D., Dauncey, P., David, A., Davies, G., Day, E., DeBarbaro, P., De Guio, F., de La Taille, C., De Silva, M., Debbins, P., Delagnes, E., Deltoro, J. M., Derylo, G., de Almeida, P. G. Dias, Diaz, D., Dinaucourt, P., Dittmann, J., Dragicevic, M., Dugad, S., Dutta, V., Dutta, S., Eckdahl, J., Edberg, T. K., Berni, M. El, Eno, S. C., Ershov, Yu., Everaerts, P., Extier, S., Fahim, F., Fallon, C., Alves, B. A. Fontana Santos, Frahm, E., Franzoni, G., Freeman, J., French, T., Guler, E. Gurpinar, Guler, Y., Gagnan, M., Gandhi, P., Ganjour, S., Garcia-Bellido, A., Gecse, Z., Geerebaert, Y., Gerwig, H., Gevin, O., Gilbert, W., Gilbert, A., Gill, K., Gingu, C., Gninenko, S., Golunov, A., Golutvin, I., Gonzalez, T., Gorbounov, N., Gouskos, L., Gu, Y., Guilloux, F., Gülmez, E., Hammer, M., Harilal, A., Hatakeyama, K., Heering, A., Hegde, V., Heintz, U., Hinger, V., Hinton, N., Hirschauer, J., Hoff, J., Hou, W. S., Isik, C., Incandela, J., Jain, S., Jheng, H. R., Joshi, U., Kara, O., Kachanov, V., Kalinin, A., Kameshwar, R., Kaminskiy, A., Karneyeu, A., Kaya, O., Kaya, M., Khukhunaishvili, A., Kim, S., Koetz, K., Kolberg, T., Kristić, A., Krohn, M., Krüger, K., Kulagin, N., Kulis, S., Kunori, S., Kuo, C. M., Kuryatkov, V., Kyre, S., Köseyan, O. K., Lai, Y., Lamichhane, K., Landsberg, G., Langford, J., Lee, M. Y., Levin, A., Li, A., Li, B., Li, J. -H., Liao, H., Lincoln, D., Linssen, L., Lipton, R., Liu, Y., Lobanov, A., Lu, R. S., Lysova, I., Magnan, A. M., Magniette, F., Maier, A. A., Malakhov, A., Mandjavize, I., Mannelli, M., Mans, J., Marchioro, A., Martelli, A., Masterson, P., Meng, B., Mengke, T., Mestvirishvili, A., Mirza, I., Moccia, S., Morrissey, I., Mudholkar, T., Musić, J., Musienko, I., Nabili, S., Nagar, A., Nikitenko, A., Noonan, D., Noy, M., Nurdan, K., Ochando, C., Odegard, B., Odell, N., Onel, Y., Ortez, W., Ozegović, J., Rodriguez, L. Pacheco, Paganis, E., Pagenkopf, D., Palladino, V., Pandey, S., Pantaleo, F., Papageorgakis, C., Papakrivopoulos, I., Parshook, J., Pastika, N., Paulini, M., Paulitsch, P., Peltola, T., Gomes, R. Pereira, Perkins, H., Petiot, P., Pitters, F., Prosper, H., Prvan, M., Puljak, I., Quast, T., Quinn, R., Quinnan, M., Rapacz, K., Raux, L., Reichenbach, G., Reinecke, M., Revering, M., Rodriguez, A., Romanteau, T., Rose, A., Rovere, M., Roy, A., Rubinov, P., Rusack, R., Simsek, A. E., Sozbilir, U., Sahin, O. M., Sanchez, A., Saradhy, R., Sarkar, T., Sarkisla, M. A., Sauvan, J. B., Schmidt, I., Schmitt, M., Scott, E., Seez, C., Sefkow, F., Sharma, S., Shein, I., Shenai, A., Shukla, R., Sicking, E., Sieberer, P., Sirois, Y., Smirnov, V., Spencer, E., Steen, A., Strait, J., Strebler, T., Strobbe, N., Su, J. W., Sukhov, E., Sun, L., Sun, M., Syal, C., Tali, B., Tok, U. G., Topaksu, A. Kayis, Tan, C. L., Tastan, I., Tatli, T., Thaus, R., Tekten, S., Thienpont, D., Pierre-Emile, T., Tiras, E., Titov, M., Tlisov, D., Troska, J., Tsamalaidze, Z., Tsipolitis, G., Tsirou, A., Tyurin, N., Undleeb, S., Urbanski, D., Ustinov, V., Uzunian, A., van de Klundert, M., Varela, J., Velasco, M., Pinto, M. Vicente Barreto, da Silva, P. M., Virdee, T., de Oliveira, R. Vizinho, Voelker, J., Voirin, E., Wang, Z., Wang, X., Wang, F., Wayne, M., Webb, S. N., Weinberg, M., Whitbeck, A., White, D., Wickwire, R., Wilson, J. S., Wu, H. Y., Wu, L., Yeh, C. H, Yohay, R., Yu, G. B., Yu, S. S., Yu, D., Yumiceva, F., Zacharopoulou, A., Zamiatin, N., Zarubin, A., Zenz, S., Zhang, H., and Zhang, J.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

As part of its HL-LHC upgrade program, the CMS Collaboration is developing a High Granularity Calorimeter (CE) to replace the existing endcap calorimeters. The CE is a sampling calorimeter with unprecedented transverse and longitudinal readout for both electromagnetic (CE-E) and hadronic (CE-H) compartments. The calorimeter will be built with $\sim$30,000 hexagonal silicon modules. Prototype modules have been constructed with 6-inch hexagonal silicon sensors with cell areas of 1.1~$cm^2$, and the SKIROC2-CMS readout ASIC. Beam tests of different sampling configurations were conducted with the prototype modules at DESY and CERN in 2017 and 2018. This paper describes the construction and commissioning of the CE calorimeter prototype, the silicon modules used in the construction, their basic performance, and the methods used for their calibration., Comment: 35 pages, submitted to JINST

Published
2020

16. The DAQ system of the 12,000 Channel CMS High Granularity Calorimeter Prototype

Author

Acar, B., Adamov, G., Adloff, C., Afanasiev, S., Akchurin, N., Akgün, B., Alhusseini, M., Alison, J., Altopp, G., Alyari, M., An, S., Anagul, S., Andreev, I., Andrews, M., Aspell, P., Atakisi, I. A., Bach, O., Baden, A., Bakas, G., Bakshi, A., Bargassa, P., Barney, D., Becheva, E., Behera, P., Belloni, A., Bergauer, T., Besancon, M., Bhattacharya, S., Bhowmik, D., Bloch, P., Bodek, A., Bonanomi, M., Bonnemaison, A., Bonomally, S., Borg, J., Bouyjou, F., Braga, D., Brashear, J., Brondolin, E., Bryant, P., Bueghly, J., Bilki, B., Burkle, B., Butler-Nalin, A., Callier, S., Calvet, D., Cao, X., Caraway, B., Caregari, S., Ceard, L., Cekmecelioglu, Y. C., Cerminara, G., Charitonidis, N., Chatterjee, R., Chen, Y. M., Chen, Z., Cheng, K. y., Chernichenko, S., Cheung, H., Chien, C. H., Choudhury, S., Čoko, D., Collura, G., Couderc, F., Dumanoglu, I., Dannheim, D., Dauncey, P., David, A., Davies, G., Day, E., DeBarbaro, P., De Guio, F., de La Taille, C., De Silva, M., Debbins, P., Delagnes, E., Deltoro, J. M., Derylo, G., de Almeida, P. G. Dias, Diaz, D., Dinaucourt, P., Dittmann, J., Dragicevic, M., Dugad, S., Dutta, V., Dutta, S., Eckdahl, J., Edberg, T. K., Berni, M. El, Eno, S. C., Ershov, Yu., Everaerts, P., Extier, S., Fahim, F., Fallon, C., Alves, B. A. Fontana Santos, Frahm, E., Franzoni, G., Freeman, J., French, T., Guler, E. Gurpinar, Guler, Y., Gagnan, M., Gandhi, P., Ganjour, S., Garcia-Bellido, A., Gecse, Z., Geerebaert, Y., Gerwig, H., Gevin, O., Gilbert, W., Gilbert, A., Gill, K., Gingu, C., Gninenko, S., Golunov, A., Golutvin, I., Gonzalez, T., Gorbounov, N., Gouskos, L., Gu, Y., Guilloux, F., Gülmez, E., Hammer, M., Harilal, A., Hatakeyama, K., Heering, A., Hegde, V., Heintz, U., Hinger, V., Hinton, N., Hirschauer, J., Hoff, J., Hou, W. S., Isik, C., Incandela, J., Jain, S., Jheng, H. R., Joshi, U., Kara, O., Kachanov, V., Kalinin, A., Kameshwar, R., Kaminskiy, A., Karneyeu, A., Kaya, O., Kaya, M., Khukhunaishvili, A., Kim, S., Koetz, K., Kolberg, T., Kristić, A., Krohn, M., Krüger, K., Kulagin, N., Kulis, S., Kunori, S., Kuo, C. M., Kuryatkov, V., Kyre, S., Köseyan, O. K., Lai, Y., Lamichhane, K., Landsberg, G., Langford, J., Lee, M. Y., Levin, A., Li, A., Li, B., Li, J. -H., Liao, H., Lincoln, D., Linssen, L., Lipton, R., Liu, Y., Lobanov, A., Lu, R. S., Lysova, I., Magnan, A. M., Magniette, F., Maier, A. A., Malakhov, A., Mandjavize, I., Mannelli, M., Mans, J., Marchioro, A., Martelli, A., Masterson, P., Meng, B., Mengke, T., Mestvirishvili, A., Mirza, I., Moccia, S., Morrissey, I., Mudholkar, T., Musić, J., Musienko, I., Nabili, S., Nagar, A., Nikitenko, A., Noonan, D., Noy, M., Nurdan, K., Ochando, C., Odegard, B., Odell, N., Onel, Y., Ortez, W., Ozegović, J., Rodriguez, L. Pacheco, Paganis, E., Pagenkopf, D., Palladino, V., Pandey, S., Pantaleo, F., Papageorgakis, C., Papakrivopoulos, I., Parshook, J., Pastika, N., Paulini, M., Paulitsch, P., Peltola, T., Gomes, R. Pereira, Perkins, H., Petiot, P., Pitters, F., Prosper, H., Prvan, M., Puljak, I., Quast, T., Quinn, R., Quinnan, M., Rapacz, K., Raux, L., Reichenbach, G., Reinecke, M., Revering, M., Rodriguez, A., Romanteau, T., Rose, A., Rovere, M., Roy, A., Rubinov, P., Rusack, R., Simsek, A. E., Sozbilir, U., Sahin, O. M., Sanchez, A., Saradhy, R., Sarkar, T., Sarkisla, M. A., Sauvan, J. B., Schmidt, I., Schmitt, M., Scott, E., Seez, C., Sefkow, F., Sharma, S., Shein, I., Shenai, A., Shukla, R., Sicking, E., Sieberer, P., Sirois, Y., Smirnov, V., Spencer, E., Steen, A., Strait, J., Strebler, T., Strobbe, N., Su, J. W., Sukhov, E., Sun, L., Sun, M., Syal, C., Tali, B., Tok, U. G., Topaksu, A. Kayis, Tan, C. L., Tastan, I., Tatli, T., Thaus, R., Tekten, S., Thienpont, D., Pierre-Emile, T., Tiras, E., Titov, M., Tlisov, D., Troska, J., Tsamalaidze, Z., Tsipolitis, G., Tsirou, A., Tyurin, N., Undleeb, S., Urbanski, D., Ustinov, V., Uzunian, A., van de Klundert, M., Varela, J., Velasco, M., Pinto, M. Vicente Barreto, da Silva, P. M., Virdee, T., de Oliveira, R. Vizinho, Voelker, J., Voirin, E., Wang, Z., Wang, X., Wang, F., Wayne, M., Webb, S. N., Weinberg, M., Whitbeck, A., White, D., Wickwire, R., Wilson, J. S., Wu, H. Y., Wu, L., Yeh, C. H, Yohay, R., Yu, G. B., Yu, S. S., Yu, D., Yumiceva, F., Zacharopoulou, A., Zamiatin, N., Zarubin, A., Zenz, S., Zhang, H., and Zhang, J.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The CMS experiment at the CERN LHC will be upgraded to accommodate the 5-fold increase in the instantaneous luminosity expected at the High-Luminosity LHC (HL-LHC). Concomitant with this increase will be an increase in the number of interactions in each bunch crossing and a significant increase in the total ionising dose and fluence. One part of this upgrade is the replacement of the current endcap calorimeters with a high granularity sampling calorimeter equipped with silicon sensors, designed to manage the high collision rates. As part of the development of this calorimeter, a series of beam tests have been conducted with different sampling configurations using prototype segmented silicon detectors. In the most recent of these tests, conducted in late 2018 at the CERN SPS, the performance of a prototype calorimeter equipped with ${\approx}12,000\rm{~channels}$ of silicon sensors was studied with beams of high-energy electrons, pions and muons. This paper describes the custom-built scalable data acquisition system that was built with readily available FPGA mezzanines and low-cost Raspberry PI computers.

Published
2020
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17. Quantifying and mapping covalent bond scission during elastomer fracture

Author

Slootman, Juliette, Waltz, Victoria, Yeh, C. Joshua, Baumann, Christoph, Göst, Robert, Comtet, Jean, and Creton, Costantino

Subjects
Condensed Matter - Soft Condensed Matter, Physics - Chemical Physics
Abstract

Many new soft but tough rubbery materials have been recently discovered and new applications such as flexible prosthetics, stretchable electrodes or soft robotics continuously emerge. Yet, a credible multi-scale quantitative picture of damage and fracture of these materials has still not emerged, due to our fundamental inability to disentangle the irreversible scission of chemical bonds along the fracture path from dissipation by internal molecular friction. Here, by coupling new fluorogenic mechanochemistry with quantitative confocal microscopy mapping, we uncover how many and where covalent bonds are broken as an elastomer fractures. Our measurements reveal that bond scission near the crack plane can be delocalized over up to hundreds of micrometers and increase by a factor of 100 depending on temperature and stretch rate, pointing to an intricated coupling between strain rate dependent viscous dissipation and strain dependent irreversible network scission. These findings paint an entirely novel picture of fracture in soft materials, where energy dissipated by covalent bond scission accounts for a much larger fraction of the total fracture energy than previously believed. Our results pioneer the sensitive, quantitative and spatially-resolved detection of bond scission to assess material damage in a variety of soft materials and their applications.

Published
2020
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18. Physics potential of timing layers in future collider detectors

Author

Chekanov, S. V., Kotwal, A. V., Yeh, C. -H., and Yu, S. -S.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Phenomenology
Abstract

The physics potential of timing layers with a few tens of pico-second resolution in the calorimeters of future collider detectors is explored. These studies show how such layers can be used for particle identification and illustrate the potential for detecting new event signatures originating from physics beyond the standard model., Comment: 14 pages, 7 figures

Published
2020
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20. Studies of granularity of a hadronic calorimeter for tens-of-TeV jets at a 100 TeV $pp$ collider

Author

Yeh, C. -H., Chekanov, S. V., Kotwal, A. V., Proudfoot, J., Sen, S., Tran, N. V., and Yu, S. -S.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

Jet substructure variables for hadronic jets with transverse momenta in the range from 2.5 TeV to 20 TeV were studied using several designs for the spatial size of calorimeter cells. The studies used the full Geant4 simulation of calorimeter response combined with realistic reconstruction of calorimeter clusters. In most cases, the results indicate that the performance of jet-substructure reconstruction improves with reducing cell size of a hadronic calorimeter from $\Delta \eta \times \Delta \phi = 0.087\times0.087$, which are similar to the cell sizes of the calorimeters of LHC experiments, by a factor of four, to $0.022\times0.022$., Comment: 19 pages, 57 figures

Published
2019
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21. Timing performance of the CMS High Granularity Calorimeter prototype

Author

Acar, B, Adamov, G, Adloff, C, Afanasiev, S, Akchurin, N, Akgun, B, Khan, F, Alhusseini, M, Alison, J, Alpana, A, Altopp, G, Alyari, M, An, S, Anagul, S, Andreev, I, Aspell, P, Atakisi, I, Bach, O, Baden, A, Bakas, G, Bakshi, A, Bannerjee, S, Bargassa, P, Barney, D, Beaudette, F, Beaujean, F, Becheva, E, Becker, A, Behera, P, Belloni, A, Bergauer, T, Besancon, M, Bhattacharya, S, Bhowmik, D, Bilki, B, Bloch, P, Bodek, A, Bonanomi, M, Bonnemaison, A, Bonomally, S, Borg, J, Bouyjou, F, Bower, N, Braga, D, Brashear, J, Brondolin, E, Bryant, P, Buchot Perraguin, A, Bueghly, J, Burkle, B, Butler-Nalin, A, Bychkova, O, Callier, S, Calvet, D, Cao, X, Cappati, A, Caraway, B, Caregari, S, Cauchois, A, Ceard, L, Cekmecelioglu, Y, Cerci, S, Cerminara, G, Chadeeva, M, Charitonidis, N, Chatterjee, R, Chen, Y, Chen, Z, Cheng, H, Cheng, K, Chernichenko, S, Cheung, H, Chien, C, Choudhury, S, Coko, D, Collura, G, Couderc, F, Danilov, M, Dannheim, D, Daoud, W, Dauncey, P, David, A, Davies, G, Davignon, O, Day, E, De Barbaro, P, De Guio, F, de La Taille, C, De Silva, M, Debbins, P, Defranchis, M, Delagnes, E, Deltoro Berrio, J, Derylo, G, Dias de Almeida, P, Diaz, D, Dinaucourt, P, Dittmann, J, Dragicevic, M, Dugad, S, Dulucq, F, Dumanoglu, I, Dutta, V, Dutta, S, Dunser, M, Eckdahl, J, Edberg, T, El Berni, M, Elias, F, Eno, S, Ershov, Y, Everaerts, P, Extier, S, Fahim, F, Fallon, C, Fedi, G, Fontana Santos Alves, B, Frahm, E, Franzoni, G, Freeman, J, French, T, Gandhi, P, Ganjour, S, Gao, X, Garcia-Bellido, A, Gastaldi, F, Gecse, Z, Geerebaert, Y, Gerwig, H, Gevin, O, Ghosh, S, Gilbert, A, Gilbert, W, Gill, K, Gingu, C, Gninenko, S, Golunov, A, Golutvin, I, Gonzalez, T, Gorbounov, N, Gouskos, L, Gray, A, Gu, Y, Guilloux, F, Guler, Y, Gulmez, E, Guo, J, Gurpinar Guler, E, Hammer, M, Hassanshahi, H, Hatakeyama, K, Heering, A, Hegde, V, Heintz, U, Hinton, N, Hirschauer, J, Hoff, J, Hou, W, Hou, X, Hua, H, Incandela, J, Irshad, A, Isik, C, Jain, S, Jheng, H, Joshi, U, Kachanov, V, Kalinin, A, Kalipoliti, L, Kaminskiy, A, Kapoor, A, Kara, O, Karneyeu, A, Kaya, M, Kaya, O, Kayis Topaksu, A, Khukhunaishvili, A, Kieseler, J, Kilpatrick, M, Kim, S, Koetz, K, Kolberg, T, Koseyan, O, Kristic, A, Krohn, M, Kruger, K, Kulagin, N, Kulis, S, Kunori, S, Kuo, C, Kuryatkov, V, Kyre, S, Lai, Y, Lamichhane, K, Landsberg, G, Lange, C, Langford, J, Lee, M, Levin, A, Li, A, Li, B, Li, J, Li, Y, Liao, H, Lincoln, D, Linssen, L, Lipton, R, Liu, Y, Lobanov, A, Lu, R, Lupi, M, Lysova, I, Magnan, A, Magniette, F, Mahjoub, A, Maier, A, Malakhov, A, Mallios, S, Mannelli, M, Mans, J, Marchioro, A, Martelli, A, Martinez, G, Masterson, P, Meng, B, Mengke, T, Mestvirishvili, A, Mirza, I, Moccia, S, Mohanty, G, Monti, F, Morrissey, I, Murthy, S, Music, J, Musienko, Y, Nabili, S, Nagar, A, Nguyen, M, Nikitenko, A, Noonan, D, Noy, M, Nurdan, K, Ochando, C, Odegard, B, Odell, N, Okawa, H, Onel, Y, Ortez, W, Ozegovic, J, Ozkorucuklu, S, Paganis, E, Pagenkopf, D, Palladino, V, Pandey, S, Pantaleo, F, Papageorgakis, C, Papakrivopoulos, I, Parshook, J, Pastika, N, Paulini, M, Paulitsch, P, Peltola, T, Pereira Gomes, R, Perkins, H, Petiot, P, Pierre-Emile, T, Pitters, F, Popova, E, Prosper, H, Prvan, M, Puljak, I, Qu, H, Quast, T, Quinn, R, Quinnan, M, Ramos Garcia, M, Rao, K, Rapacz, K, Raux, L, Reichenbach, G, Reinecke, M, Revering, M, Roberts, A, Romanteau, T, Rose, A, Rovere, M, Roy, A, Rubinov, P, Rusack, R, Rusinov, V, Ryjov, V, Sahin, M, Salerno, R, Sanchez Rodriguez, A, Saradhy, R, Sarkar, T, Sarkisla, M, Sauvan, J, Schmidt, I, Schmitt, M, Scott, E, Seez, C, Sefkow, F, Sharma, S, Shein, I, Shenai, A, Shukla, R, Sicking, E, Sieberer, P, Silva, P, Simsek, A, Sirois, Y, Smirnov, V, Sozbilir, U, Spencer, E, Steen, A, Strait, J, Strobbe, N, Su, J, Sukhov, E, Sun, L, Sunar Cerci, D, Syal, C, Tali, B, Tan, C, Tao, J, Tastan, I, Tatli, T, Thaus, R, Tekten, S, Thienpont, D, Tiras, E, Titov, M, Tlisov, D, Tok, U, Troska, J, Tsai, L, Tsamalaidze, Z, Tsipolitis, G, Tsirou, A, Tyurin, N, Undleeb, S, Urbanski, D, Ustinov, V, Uzunian, A, Van de Klundert, M, Varela, J, Velasco, M, Viazlo, O, Vicente Barreto Pinto, M, Vichoudis, P, Virdee, T, Vizinho de Oliveira, R, Voelker, J, Voirin, E, Vojinovic, M, Wade, A, Wang, C, Wang, F, Wang, X, Wang, Z, Wayne, M, Webb, S, Whitbeck, A, White, D, Wickwire, R, Wilson, J, Winter, D, Wu, H, Wu, L, Wulansatiti Nursanto, M, Yeh, C, Yohay, R, Yu, D, Yu, G, Yu, S, Yuan, C, Yumiceva, F, Yusuff, I, Zacharopoulou, A, Zamiatin, N, Zarubin, A, Zenz, S, Zghiche, A, Zhang, H, Zhang, J, Zhang, Y, Zhang, Z, Acar B., Adamov G., Adloff C., Afanasiev S., Akchurin N., Akgun B., Khan F., Alhusseini M., Alison J., Alpana A., Altopp G., Alyari M., An S., Anagul S., Andreev I., Aspell P., Atakisi I., Bach O., Baden A., Bakas G., Bakshi A., Bannerjee S., Bargassa P., Barney D., Beaudette F., Beaujean F., Becheva E., Becker A., Behera P., Belloni A., Bergauer T., Besancon M., Bhattacharya S., Bhowmik D., Bilki B., Bloch P., Bodek A., Bonanomi M., Bonnemaison A., Bonomally S., Borg J., Bouyjou F., Bower N., Braga D., Brashear J., Brondolin E., Bryant P., Buchot Perraguin A., Bueghly J., Burkle B., Butler-Nalin A., Bychkova O., Callier S., Calvet D., Cao X., Cappati A., Caraway B., Caregari S., Cauchois A., Ceard L., Cekmecelioglu Y., Cerci S., Cerminara G., Chadeeva M., Charitonidis N., Chatterjee R., Chen Y., Chen Z., Cheng H., Cheng K., Chernichenko S., Cheung H., Chien C., Choudhury S., Coko D., Collura G., Couderc F., Danilov M., Dannheim D., Daoud W., Dauncey P., David A., Davies G., Davignon O., Day E., De Barbaro P., De Guio F., de La Taille C., De Silva M., Debbins P., Defranchis M., Delagnes E., Deltoro Berrio J., Derylo G., Dias de Almeida P., Diaz D., Dinaucourt P., Dittmann J., Dragicevic M., Dugad S., Dulucq F., Dumanoglu I., Dutta V., Dutta S., Dunser M., Eckdahl J., Edberg T., El Berni M., Elias F., Eno S., Ershov Y., Everaerts P., Extier S., Fahim F., Fallon C., Fedi G., Fontana Santos Alves B., Frahm E., Franzoni G., Freeman J., French T., Gandhi P., Ganjour S., Gao X., Garcia-Bellido A., Gastaldi F., Gecse Z., Geerebaert Y., Gerwig H., Gevin O., Ghosh S., Gilbert A., Gilbert W., Gill K., Gingu C., Gninenko S., Golunov A., Golutvin I., Gonzalez T., Gorbounov N., Gouskos L., Gray A., Gu Y., Guilloux F., Guler Y., Gulmez E., Guo J., Gurpinar Guler E., Hammer M., Hassanshahi H., Hatakeyama K., Heering A., Hegde V., Heintz U., Hinton N., Hirschauer J., Hoff J., Hou W. -S., Hou X., Hua H., Incandela J., Irshad A., Isik C., Jain S., Jheng H., Joshi U., Kachanov V., Kalinin A., Kalipoliti L., Kaminskiy A., Kapoor A., Kara O., Karneyeu A., Kaya M., Kaya O., Kayis Topaksu A., Khukhunaishvili A., Kieseler J., Kilpatrick M., Kim S., Koetz K., Kolberg T., Koseyan O., Kristic A., Krohn M., Kruger K., Kulagin N., Kulis S., Kunori S., Kuo C., Kuryatkov V., Kyre S., Lai Y., Lamichhane K., Landsberg G., Lange C., Langford J., Lee M., Levin A., Li A., Li B., Li J., Li Y., Liao H., Lincoln D., Linssen L., Lipton R., Liu Y., Lobanov A., Lu R. -S., Lupi M., Lysova I., Magnan A. -M., Magniette F., Mahjoub A., Maier A., Malakhov A., Mallios S., Mannelli M., Mans J., Marchioro A., Martelli A., Martinez G., Masterson P., Meng B., Mengke T., Mestvirishvili A., Mirza I., Moccia S., Mohanty G., Monti F., Morrissey I., Murthy S., Music J., Musienko Y., Nabili S., Nagar A., Nguyen M., Nikitenko A., Noonan D., Noy M., Nurdan K., Ochando C., Odegard B., Odell N., Okawa H., Onel Y., Ortez W., Ozegovic J., Ozkorucuklu S., Paganis E., Pagenkopf D., Palladino V., Pandey S., Pantaleo F., Papageorgakis C., Papakrivopoulos I., Parshook J., Pastika N., Paulini M., Paulitsch P., Peltola T., Pereira Gomes R., Perkins H., Petiot P., Pierre-Emile T., Pitters F., Popova E., Prosper H., Prvan M., Puljak I., Qu H., Quast T., Quinn R., Quinnan M., Ramos Garcia M., Rao K., Rapacz K., Raux L., Reichenbach G., Reinecke M., Revering M., Roberts A., Romanteau T., Rose A., Rovere M., Roy A., Rubinov P., Rusack R., Rusinov V., Ryjov V., Sahin M., Salerno R., Sanchez Rodriguez A., Saradhy R., Sarkar T., Sarkisla M., Sauvan J., Schmidt I., Schmitt M., Scott E., Seez C., Sefkow F., Sharma S., Shein I., Shenai A., Shukla R., Sicking E., Sieberer P., Silva P., Simsek A., Sirois Y., Smirnov V., Sozbilir U., Spencer E., Steen A., Strait J., Strobbe N., Su J., Sukhov E., Sun L., Sunar Cerci D., Syal C., Tali B., Tan C., Tao J., Tastan I., Tatli T., Thaus R., Tekten S., Thienpont D., Tiras E., Titov M., Tlisov D., Tok U., Troska J., Tsai L. -S., Tsamalaidze Z., Tsipolitis G., Tsirou A., Tyurin N., Undleeb S., Urbanski D., Ustinov V., Uzunian A., Van de Klundert M., Varela J., Velasco M., Viazlo O., Vicente Barreto Pinto M., Vichoudis P., Virdee T., Vizinho de Oliveira R., Voelker J., Voirin E., Vojinovic M., Wade A., Wang C., Wang F., Wang X., Wang Z., Wayne M., Webb S., Whitbeck A., White D., Wickwire R., Wilson J., Winter D., Wu H., Wu L., Wulansatiti Nursanto M., Yeh C., Yohay R., Yu D., Yu G., Yu S., Yuan C., Yumiceva F., Yusuff I., Zacharopoulou A., Zamiatin N., Zarubin A., Zenz S., Zghiche A., Zhang H., Zhang J., Zhang Y., Zhang Z., Acar, B, Adamov, G, Adloff, C, Afanasiev, S, Akchurin, N, Akgun, B, Khan, F, Alhusseini, M, Alison, J, Alpana, A, Altopp, G, Alyari, M, An, S, Anagul, S, Andreev, I, Aspell, P, Atakisi, I, Bach, O, Baden, A, Bakas, G, Bakshi, A, Bannerjee, S, Bargassa, P, Barney, D, Beaudette, F, Beaujean, F, Becheva, E, Becker, A, Behera, P, Belloni, A, Bergauer, T, Besancon, M, Bhattacharya, S, Bhowmik, D, Bilki, B, Bloch, P, Bodek, A, Bonanomi, M, Bonnemaison, A, Bonomally, S, Borg, J, Bouyjou, F, Bower, N, Braga, D, Brashear, J, Brondolin, E, Bryant, P, Buchot Perraguin, A, Bueghly, J, Burkle, B, Butler-Nalin, A, Bychkova, O, Callier, S, Calvet, D, Cao, X, Cappati, A, Caraway, B, Caregari, S, Cauchois, A, Ceard, L, Cekmecelioglu, Y, Cerci, S, Cerminara, G, Chadeeva, M, Charitonidis, N, Chatterjee, R, Chen, Y, Chen, Z, Cheng, H, Cheng, K, Chernichenko, S, Cheung, H, Chien, C, Choudhury, S, Coko, D, Collura, G, Couderc, F, Danilov, M, Dannheim, D, Daoud, W, Dauncey, P, David, A, Davies, G, Davignon, O, Day, E, De Barbaro, P, De Guio, F, de La Taille, C, De Silva, M, Debbins, P, Defranchis, M, Delagnes, E, Deltoro Berrio, J, Derylo, G, Dias de Almeida, P, Diaz, D, Dinaucourt, P, Dittmann, J, Dragicevic, M, Dugad, S, Dulucq, F, Dumanoglu, I, Dutta, V, Dutta, S, Dunser, M, Eckdahl, J, Edberg, T, El Berni, M, Elias, F, Eno, S, Ershov, Y, Everaerts, P, Extier, S, Fahim, F, Fallon, C, Fedi, G, Fontana Santos Alves, B, Frahm, E, Franzoni, G, Freeman, J, French, T, Gandhi, P, Ganjour, S, Gao, X, Garcia-Bellido, A, Gastaldi, F, Gecse, Z, Geerebaert, Y, Gerwig, H, Gevin, O, Ghosh, S, Gilbert, A, Gilbert, W, Gill, K, Gingu, C, Gninenko, S, Golunov, A, Golutvin, I, Gonzalez, T, Gorbounov, N, Gouskos, L, Gray, A, Gu, Y, Guilloux, F, Guler, Y, Gulmez, E, Guo, J, Gurpinar Guler, E, Hammer, M, Hassanshahi, H, Hatakeyama, K, Heering, A, Hegde, V, Heintz, U, Hinton, N, Hirschauer, J, Hoff, J, Hou, W, Hou, X, Hua, H, Incandela, J, Irshad, A, Isik, C, Jain, S, Jheng, H, Joshi, U, Kachanov, V, Kalinin, A, Kalipoliti, L, Kaminskiy, A, Kapoor, A, Kara, O, Karneyeu, A, Kaya, M, Kaya, O, Kayis Topaksu, A, Khukhunaishvili, A, Kieseler, J, Kilpatrick, M, Kim, S, Koetz, K, Kolberg, T, Koseyan, O, Kristic, A, Krohn, M, Kruger, K, Kulagin, N, Kulis, S, Kunori, S, Kuo, C, Kuryatkov, V, Kyre, S, Lai, Y, Lamichhane, K, Landsberg, G, Lange, C, Langford, J, Lee, M, Levin, A, Li, A, Li, B, Li, J, Li, Y, Liao, H, Lincoln, D, Linssen, L, Lipton, R, Liu, Y, Lobanov, A, Lu, R, Lupi, M, Lysova, I, Magnan, A, Magniette, F, Mahjoub, A, Maier, A, Malakhov, A, Mallios, S, Mannelli, M, Mans, J, Marchioro, A, Martelli, A, Martinez, G, Masterson, P, Meng, B, Mengke, T, Mestvirishvili, A, Mirza, I, Moccia, S, Mohanty, G, Monti, F, Morrissey, I, Murthy, S, Music, J, Musienko, Y, Nabili, S, Nagar, A, Nguyen, M, Nikitenko, A, Noonan, D, Noy, M, Nurdan, K, Ochando, C, Odegard, B, Odell, N, Okawa, H, Onel, Y, Ortez, W, Ozegovic, J, Ozkorucuklu, S, Paganis, E, Pagenkopf, D, Palladino, V, Pandey, S, Pantaleo, F, Papageorgakis, C, Papakrivopoulos, I, Parshook, J, Pastika, N, Paulini, M, Paulitsch, P, Peltola, T, Pereira Gomes, R, Perkins, H, Petiot, P, Pierre-Emile, T, Pitters, F, Popova, E, Prosper, H, Prvan, M, Puljak, I, Qu, H, Quast, T, Quinn, R, Quinnan, M, Ramos Garcia, M, Rao, K, Rapacz, K, Raux, L, Reichenbach, G, Reinecke, M, Revering, M, Roberts, A, Romanteau, T, Rose, A, Rovere, M, Roy, A, Rubinov, P, Rusack, R, Rusinov, V, Ryjov, V, Sahin, M, Salerno, R, Sanchez Rodriguez, A, Saradhy, R, Sarkar, T, Sarkisla, M, Sauvan, J, Schmidt, I, Schmitt, M, Scott, E, Seez, C, Sefkow, F, Sharma, S, Shein, I, Shenai, A, Shukla, R, Sicking, E, Sieberer, P, Silva, P, Simsek, A, Sirois, Y, Smirnov, V, Sozbilir, U, Spencer, E, Steen, A, Strait, J, Strobbe, N, Su, J, Sukhov, E, Sun, L, Sunar Cerci, D, Syal, C, Tali, B, Tan, C, Tao, J, Tastan, I, Tatli, T, Thaus, R, Tekten, S, Thienpont, D, Tiras, E, Titov, M, Tlisov, D, Tok, U, Troska, J, Tsai, L, Tsamalaidze, Z, Tsipolitis, G, Tsirou, A, Tyurin, N, Undleeb, S, Urbanski, D, Ustinov, V, Uzunian, A, Van de Klundert, M, Varela, J, Velasco, M, Viazlo, O, Vicente Barreto Pinto, M, Vichoudis, P, Virdee, T, Vizinho de Oliveira, R, Voelker, J, Voirin, E, Vojinovic, M, Wade, A, Wang, C, Wang, F, Wang, X, Wang, Z, Wayne, M, Webb, S, Whitbeck, A, White, D, Wickwire, R, Wilson, J, Winter, D, Wu, H, Wu, L, Wulansatiti Nursanto, M, Yeh, C, Yohay, R, Yu, D, Yu, G, Yu, S, Yuan, C, Yumiceva, F, Yusuff, I, Zacharopoulou, A, Zamiatin, N, Zarubin, A, Zenz, S, Zghiche, A, Zhang, H, Zhang, J, Zhang, Y, Zhang, Z, Acar B., Adamov G., Adloff C., Afanasiev S., Akchurin N., Akgun B., Khan F., Alhusseini M., Alison J., Alpana A., Altopp G., Alyari M., An S., Anagul S., Andreev I., Aspell P., Atakisi I., Bach O., Baden A., Bakas G., Bakshi A., Bannerjee S., Bargassa P., Barney D., Beaudette F., Beaujean F., Becheva E., Becker A., Behera P., Belloni A., Bergauer T., Besancon M., Bhattacharya S., Bhowmik D., Bilki B., Bloch P., Bodek A., Bonanomi M., Bonnemaison A., Bonomally S., Borg J., Bouyjou F., Bower N., Braga D., Brashear J., Brondolin E., Bryant P., Buchot Perraguin A., Bueghly J., Burkle B., Butler-Nalin A., Bychkova O., Callier S., Calvet D., Cao X., Cappati A., Caraway B., Caregari S., Cauchois A., Ceard L., Cekmecelioglu Y., Cerci S., Cerminara G., Chadeeva M., Charitonidis N., Chatterjee R., Chen Y., Chen Z., Cheng H., Cheng K., Chernichenko S., Cheung H., Chien C., Choudhury S., Coko D., Collura G., Couderc F., Danilov M., Dannheim D., Daoud W., Dauncey P., David A., Davies G., Davignon O., Day E., De Barbaro P., De Guio F., de La Taille C., De Silva M., Debbins P., Defranchis M., Delagnes E., Deltoro Berrio J., Derylo G., Dias de Almeida P., Diaz D., Dinaucourt P., Dittmann J., Dragicevic M., Dugad S., Dulucq F., Dumanoglu I., Dutta V., Dutta S., Dunser M., Eckdahl J., Edberg T., El Berni M., Elias F., Eno S., Ershov Y., Everaerts P., Extier S., Fahim F., Fallon C., Fedi G., Fontana Santos Alves B., Frahm E., Franzoni G., Freeman J., French T., Gandhi P., Ganjour S., Gao X., Garcia-Bellido A., Gastaldi F., Gecse Z., Geerebaert Y., Gerwig H., Gevin O., Ghosh S., Gilbert A., Gilbert W., Gill K., Gingu C., Gninenko S., Golunov A., Golutvin I., Gonzalez T., Gorbounov N., Gouskos L., Gray A., Gu Y., Guilloux F., Guler Y., Gulmez E., Guo J., Gurpinar Guler E., Hammer M., Hassanshahi H., Hatakeyama K., Heering A., Hegde V., Heintz U., Hinton N., Hirschauer J., Hoff J., Hou W. -S., Hou X., Hua H., Incandela J., Irshad A., Isik C., Jain S., Jheng H., Joshi U., Kachanov V., Kalinin A., Kalipoliti L., Kaminskiy A., Kapoor A., Kara O., Karneyeu A., Kaya M., Kaya O., Kayis Topaksu A., Khukhunaishvili A., Kieseler J., Kilpatrick M., Kim S., Koetz K., Kolberg T., Koseyan O., Kristic A., Krohn M., Kruger K., Kulagin N., Kulis S., Kunori S., Kuo C., Kuryatkov V., Kyre S., Lai Y., Lamichhane K., Landsberg G., Lange C., Langford J., Lee M., Levin A., Li A., Li B., Li J., Li Y., Liao H., Lincoln D., Linssen L., Lipton R., Liu Y., Lobanov A., Lu R. -S., Lupi M., Lysova I., Magnan A. -M., Magniette F., Mahjoub A., Maier A., Malakhov A., Mallios S., Mannelli M., Mans J., Marchioro A., Martelli A., Martinez G., Masterson P., Meng B., Mengke T., Mestvirishvili A., Mirza I., Moccia S., Mohanty G., Monti F., Morrissey I., Murthy S., Music J., Musienko Y., Nabili S., Nagar A., Nguyen M., Nikitenko A., Noonan D., Noy M., Nurdan K., Ochando C., Odegard B., Odell N., Okawa H., Onel Y., Ortez W., Ozegovic J., Ozkorucuklu S., Paganis E., Pagenkopf D., Palladino V., Pandey S., Pantaleo F., Papageorgakis C., Papakrivopoulos I., Parshook J., Pastika N., Paulini M., Paulitsch P., Peltola T., Pereira Gomes R., Perkins H., Petiot P., Pierre-Emile T., Pitters F., Popova E., Prosper H., Prvan M., Puljak I., Qu H., Quast T., Quinn R., Quinnan M., Ramos Garcia M., Rao K., Rapacz K., Raux L., Reichenbach G., Reinecke M., Revering M., Roberts A., Romanteau T., Rose A., Rovere M., Roy A., Rubinov P., Rusack R., Rusinov V., Ryjov V., Sahin M., Salerno R., Sanchez Rodriguez A., Saradhy R., Sarkar T., Sarkisla M., Sauvan J., Schmidt I., Schmitt M., Scott E., Seez C., Sefkow F., Sharma S., Shein I., Shenai A., Shukla R., Sicking E., Sieberer P., Silva P., Simsek A., Sirois Y., Smirnov V., Sozbilir U., Spencer E., Steen A., Strait J., Strobbe N., Su J., Sukhov E., Sun L., Sunar Cerci D., Syal C., Tali B., Tan C., Tao J., Tastan I., Tatli T., Thaus R., Tekten S., Thienpont D., Tiras E., Titov M., Tlisov D., Tok U., Troska J., Tsai L. -S., Tsamalaidze Z., Tsipolitis G., Tsirou A., Tyurin N., Undleeb S., Urbanski D., Ustinov V., Uzunian A., Van de Klundert M., Varela J., Velasco M., Viazlo O., Vicente Barreto Pinto M., Vichoudis P., Virdee T., Vizinho de Oliveira R., Voelker J., Voirin E., Vojinovic M., Wade A., Wang C., Wang F., Wang X., Wang Z., Wayne M., Webb S., Whitbeck A., White D., Wickwire R., Wilson J., Winter D., Wu H., Wu L., Wulansatiti Nursanto M., Yeh C., Yohay R., Yu D., Yu G., Yu S., Yuan C., Yumiceva F., Yusuff I., Zacharopoulou A., Zamiatin N., Zarubin A., Zenz S., Zghiche A., Zhang H., Zhang J., Zhang Y., and Zhang Z.

Abstract

This paper describes the experience with the calibration, reconstruction and evaluation of the timing capabilities of the CMS HGCAL prototype in the beam tests in 2018. The calibration procedure includes multiple steps and corrections ranging from tens of nanoseconds to a few hundred picoseconds. The timing performance is studied using signals from positron beam particles with energies between 20 GeV and 300 GeV. The performance is studied as a function of particle energy against an external timing reference as well as standalone by comparing the two different halves of the prototype. The timing resolution is found to be 60 ps for single-channel measurements and better than 20 ps for full showers at the highest energies, setting excellent perspectives for the HGCAL calorimeter performance at the HL-LHC.

Published
2024

22. Jet Substructure Variables with the SiFCC Detector at 100 TeV

Author

Yeh, C. -H, Chekanov, S. V., Kotwal, A. V., Proudfoot, J., Sen, S., Tran, N. V., and Yu, S. -S

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

Future experiments beyond the LHC era will measure high-momentum bosons ($W$, $Z$, $H$) and top quarks with strongly collimated decay products that form hadronic jets. This paper describes the studies of the performance of jet substructure variables using the Geant4 simulation of a detector designed for high energy $pp$ collisions at a 100 TeV collider. The two-prong jets from $Z' \rightarrow WW$ and three-prong jets from $Z' \rightarrow t\bar{t}$ are compared with the background from light quark jets, assuming $Z'$ masses in the range 5 -- 40 TeV. Our results indicate that the performance of jet-substructure reconstruction improves with reducing transverse cell sizes of a hadronic calorimeter from $\Delta \eta \times \Delta \phi = 0.087\times0.087$ to $0.022\times0.022$ in most cases., Comment: 2 pages, 1 figure, for The 39th International Conference on High Energy Physics (ICHEP2018)

Published
2018

26. A Novel Program-verify Free and Low Drift Multilevel Operation on Cross-point OTS-PCM for In-Memory Computing Application

Author

Chien, W. C., primary, Sung, C. L., additional, Bruce, R. L., additional, Yeh, C. W., additional, Cheng, H. Y., additional, Liu, Z. L., additional, Lai, E. K., additional, Cheng, C. W., additional, Zheng, J. X., additional, Grun, A., additional, Ray, A., additional, Daudelin, D., additional, Ho, H. Y., additional, BrightSky, M., additional, and Lung, H. L., additional

Published
2024
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28. Kinetic temperature of massive star forming molecular clumps measured with formaldehyde

Author

Tang, X. D., Henkel, C., Menten, K. M., Zheng, X. W., Esimbek, J., Zhou, J. J., Yeh, C. C., König, C., Yuan, Y., He, Y. X., and Li, D. L.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Solar and Stellar Astrophysics
Abstract

For a general understanding of the physics involved in the star formation process, measurements of physical parameters such as temperature and density are indispensable. The chemical and physical properties of dense clumps of molecular clouds are strongly affected by the kinetic temperature. Therefore, this parameter is essential for a better understanding of the interstellar medium. Formaldehyde, a molecule which traces the entire dense molecular gas, appears to be the most reliable tracer to directly measure the gas kinetic temperature.We aim to determine the kinetic temperature with spectral lines from formaldehyde and to compare the results with those obtained from ammonia lines for a large number of massive clumps.Three 218 GHz transitions (JKAKC=303-202, 322-221, and 321-220) of para-H2CO were observed with the 15m James Clerk Maxwell Telescope (JCMT) toward 30 massive clumps of the Galactic disk at various stages of high-mass star formation. Using the RADEX non-LTE model, we derive the gas kinetic temperature modeling the measured para-H2CO 322-221/303-202and 321-220/303-202 ratios. The gas kinetic temperatures derived from the para-H2CO (321-220/303-202) line ratios range from 30 to 61 K with an average of 46 K. A comparison of kinetic temperature derived from para-H2CO, NH3, and the dust emission indicates that in many cases para-H2CO traces a similar kinetic temperature to the NH3 (2,2)/(1,1) transitions and the dust associated with the HII regions. Distinctly higher temperatures are probed by para-H2CO in the clumps associated with outflows/shocks. Kinetic temperatures obtained from para-H2CO trace turbulence to a higher degree than NH3 (2,2)/(1,1) in the massive clumps. The non-thermal velocity dispersions of para-H2CO lines are positively correlated with the gas kinetic temperature. The massive clumps are significantly influenced by supersonic non-thermal motions., Comment: Accepted for publication in A&A

Published
2016
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30. Effects of excess Si and Al on synthesis of Ti3SiC2 by self-sustaining combustion in the Ti-Si–C-Al system.

Author

Yeh, C. L. and Lai, K. L.

Subjects
*SELF-propagating high-temperature synthesis, *COMBUSTION
Abstract

Fabrication of Ti3SiC2 from elemental powder compacts was conducted by combustion synthesis in the mode of self-propagating high-temperature synthesis (SHS). Samples were formulated with three atomic ratios of Ti:Si:C = 3:1:2, Ti:Si:C = 3:1.2:2 (with excess Si by 20 mol.%), and Ti:Si:C:Al = 3:1.2:2:0.1 (a Si-rich and Al-added composition). Combustion reaction was highly exothermic and combustion wave velocity (from 4.1 to 8.8 mm/s) and temperature (from 1340 to 1610 °C) increased significantly with sample compact density varied in the range of 45% to 57.5% TMD (theoretical maximum density). In addition to the sample density, excess Si and a small amount of Al contributed greatly to the formation of Ti3SiC2. For the powder compacts of 57.5% TMD, the product synthesized from the sample of Ti:Si:C = 3:1:2 was composed of Ti3SiC2, TiC, and Ti5Si3 at 64 wt.%, 28 wt.%, and 8 wt.%, respectively. The sample with excess Si by 20 mol.% yielded a product with a weight proportion of Ti3SiC2:TiC:Ti5Si3 = 70:27:3. The product having the highest yield of Ti3SiC2 was obtained from the Si-rich/Al-added sample, which produced Ti3SiC of 83 wt.%, TiC of 13 wt.% and Ti5Si3 of 4 wt.%. As-synthesized Ti3SiC2 grains were in a thin plate-like shape with 0.5–1.5 µm in thickness and 5–10 µm in length. Ti3SiC2 platelets were stacked closely into a layered structure. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Development of a Thermal Control System with Mechanically Pumped CO2 Two-Phase Loops for the AMS-02 Tracker on the ISS

Author

Alberti, G., Alvino, A., Ambrosi, G., Bardet, M., Battiston, R., Borsini, S., Cao, J. F., Chen, Y., van Es, J., Gargiulo, C., Guo, K. H., Guo, L., He, Z. H., Huang, Z. C., Koutsenko, V., Laudi, E., Lebedev, A., Lee, S. C., Li, T. X., Lin, Y. L., Lv, S. S., Menichelli, M., Miao, J. Y., Mo, D. C., Ni, J. Q., Pauw, A., Qi, X. M., Shue, G. M., Sun, D. J., Sun, X. H., Tang, C. P., Verlaat, B., Wang, Z. X., Weng, Z. L., Xiao, W. J., Xu, N. S., Yang, F. K., Yeh, C. C., Zhang, Z., and Zwartbol, T.

Subjects
Physics - Instrumentation and Detectors
Abstract

To provide a stable thermal environment for the AMS-Tracker, a thermal control system based on mechanically pumped CO2 two-phase loops was developed. It has been operating reliably in space since May 19, 2011. In this article, we summarize the design, construction, tests, and performance of the AMS-Tracker thermal control system (AMS-TTCS).

Published
2013

37. Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor.

Author

Guo, W, Liu, R, Bhardwaj, G, Yang, JC, Changou, C, Ma, A-H, Mazloom, A, Chintapalli, S, Xiao, K, Xiao, W, Kumaresan, P, Sanchez, E, Yeh, C-T, Evans, CP, Patterson, R, Lam, KS, and Kung, H-J

Subjects
Cell Line, Tumor, Animals, Humans, Mice, Mice, Nude, Prostatic Neoplasms, Taxoids, Imidazoles, Quinoxalines, RNA, Small Interfering, Antineoplastic Agents, Protein Kinase Inhibitors, Transplantation, Heterologous, Cell Proliferation, RNA Interference, Binding Sites, Protein Structure, Tertiary, Phosphorylation, Autophagy, Male, STAT3 Transcription Factor, Proto-Oncogene Proteins c-akt, Phospholipase C gamma, Protein-Tyrosine Kinases, Molecular Docking Simulation, Agammaglobulinaemia Tyrosine Kinase, Docetaxel, Cell Line, Tumor, Nude, RNA, Small Interfering, Transplantation, Heterologous, Protein Structure, Tertiary, Biochemistry and Cell Biology, Oncology and Carcinogenesis
Abstract

Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies. Etk has been shown previously to provide a strong survival and metastasis signal in human prostate cancer cells, and to confer androgen independence and drug resistance. While the role of Etk in prostate carcinogenesis is well established, the functions of Btk in prostate cancer have never been investigated, likely due to the perception that Btk is a hematopoietic, but not epithelial, kinase. Herein, we found that Btk is overexpressed in prostate cancer tissues and prostate cancer cells. The level of Btk in prostate cancer tissues correlates with cancer grades. Knockdown of Btk expression selectively inhibits the growth of prostate cancer cells, but not that of the normal prostate epithelial cells, which express very little Btk. Dual inhibition of Btk and Etk has an additive inhibitory effect on prostate cancer cell growth. To explore Btk and Etk as targets for prostate cancer, we developed a small molecule dual inhibitor of Btk and Etk, CTN06. Treatment of PC3 and other prostate cancer cells, but not immortalized prostate epithelial cells with CTN06 resulted in effective cell killing, accompanied by the attenuation of Btk/Etk signals. The killing effect of CTN06 is more potent than that of commonly used inhibitors against Src, Raf/VEGFR and EGFR. CTN06 induces apoptosis as well as autophagy in human prostate cancer cells, and is a chemo-sensitizer for docetaxel (DTX), a standard of care for metastatic prostate cancer patients. CTN06 also impeded the migration of human prostate cancer cells based on a 'wound healing' assay. The anti-cancer effect of CTN06 was further validated in vivo in a PC3 xenograft mouse model.

Published
2014

44. Interferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival

Author

Chiang K, Huang S, Wu RC, Huang SC, Yeh T, Chen M, Hsu JT, Chen L, Kuo SF, Chueh H, Juang H, Hung S, Yeh C, and Pang JS

Subjects
IFI27, cholangiocarcinoma, oncogene, angiogenesis, VEGF-A, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Kun-Chun Chiang,1 Sheng-Teng Huang,2 Ren-Chin Wu,3 Shih-Chiang Huang,3 Ta-Sen Yeh,4 Ming-Huang Chen,5 Jun-Te Hsu,4 Li-Wei Chen,6 Sheng-Fong Kuo,7 Ho-Yen Chueh,8 Horng-Heng Juang,9 Shuen-Iu Hung,10 Chun-Nan Yeh,4 Jong-Hwei S Pang11,12 1General Surgery Department, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan, ROC; 2Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan, ROC; 3Department of Anatomic Pathology, Chang Gung Memorial Hospital, Kwei-Shan, Chang Gung University, Taoyuan, Taiwan, ROC; 4General Surgery Department, Chang Gung Memorial Hospital, Kwei-Shan, Chang Gung University, Taoyuan, Taiwan, ROC; 5Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; 6Department of Gastroenterology, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan, ROC; 7Department of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan, ROC; 8Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC; 9Department of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan, ROC; 10Department and Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; 11Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, ROC; 12Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkow, Taoyuan City, Taiwan, ROC Objective: Cholangiocarcinoma (CCA) is a devastating disease. Interferon α-inducible protein 27 (IFI27), originally known to involve in innate immunity, is later found to intervene in cell proliferation, leading to inventive studies regarding the role of IFI27 in cancer treatment. We aimed to investigate the role of IFI27 in CCA.Materials and methods: Cell proliferation, migration, and invasion assays, Western blot, gene transfection and knockdown, immunofluorescent and immunohistochemical stains, and xenograft animal model were applied.Results: IFI27 knockdown in CCA cells induced cell cycle arrest in S phase, resulting in lower cell proliferative rate in vitro and in vivo. IFI27 knockdown attenuated CCA cell migration and invasion through inhibition of epithelial–mesenchymal transition, which was supported by increased E-cadherin and decreased N-cadherin and fibronectin. Filamentous actin level was also reduced. IFI27 knockdown further repressed expression and secretion of vascular endothelial growth factor (VEGF-A), a strong stimulator of angiogenesis, through downregulation of c-jun and c-fos, which was supported in vitro by the finding that human vascular endothelial cells grew more slowly in conditioned medium of IFI27 knockdown on CCA cells and in vivo by the lower erythropoietin concentration found in the xenografted tumors derived from IFI27 knockdown on CCA cells. In addition, anti-VEGF-A antibody treatment was able to repress CCA cell growth. To the contrary, IFI27 overexpression could increase CCA cell proliferation, migration, and invasion. Clinically, higher IFI27 expression was linked to inferior overall survival of CCA patients.Conclusion: Our data strongly suggest that IFI27 could be deemed as a potential target for CCA treatment. Keywords: IFI27, cholangiocarcinoma, oncogene, angiogenesis, VEGF-A, metastasis, tumor growth, cell cycle

Published
2019

45. Applying Process Virtualization Theory in E-HR Acceptance Research: Testing and Modifying an Experiment

Author

Yeh, C. Rosa, Hsiao, Shin-Yau, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kotenko, Igor, Series editor, Liu, Ting, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, Uden, Lorna, editor, Lu, Wei, editor, and Ting, I-Hsien, editor

Published
2017
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50. Magnetotransport at Domain Walls in BiFeO3

Author

He, Q, Yeh, C-H, Yang, J-C, Singh-Bhalla, G, Liang, C-W, Chiu, P-W, Catalan, G, Martin, LW, Chu, Y-H, Scott, JF, and Ramesh, R

Subjects
Mathematical Sciences, Physical Sciences, Engineering, General Physics
Abstract

Domain walls in multiferroics can exhibit intriguing behaviors that are significantly different from the bulk of the material. We investigate strong magnetoresistance in domain walls of the model multiferroic BiFeO3 by probing ordered arrays of 109° domain walls with temperature- and magnetic-field-dependent transport. We observe temperature-dependent variations in the transport mechanism and magnetoresistances as large as 60%. These results suggest that by locally breaking the symmetry of a material, such as at domain walls and structural interfaces, one can induce emergent behavior with properties that deviate significantly from the bulk.

Published
2012

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