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2. The pelvic radiograph: lines, arcs and stripes
- Author
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Yeap, PM, primary and Budak, MJ, additional
- Published
- 2021
- Full Text
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3. Findings beyond Crohn’s disease encountered on magnetic resonance enterography: a pictorial review of diseases inside and outside the bowel
- Author
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Yeap, PM, primary, Szewczyk-Bieda, M, additional, and Zealley, I, additional
- Published
- 2021
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4. Magnetic resonance imaging of the shoulder in symptomatic professional rugby players: a retrospective analysis.
- Author
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Yeap PM, Robinson P, and Grainger AJ
- Abstract
Objective: Shoulder injuries in rugby players are common due to frequent high-impact collisions and tackles. This study aimed to describe the spectrum and pattern of shoulder MRI findings in professional rugby players., Methods: Single-center retrospective study of shoulder MRI was carried out between 2012 and 2016 in symptomatic professional male rugby league and rugby union players. One hundred ten shoulder MRIs were scored for rotator cuff and long head of biceps tendons, labral, bursal, joint, and osseous abnormalities. MRI features were compared using the chi-square or Fisher's exact tests for categorical variables., Results: There were a total of one hundred ten professional male rugby players (80 rugby league and 30 rugby union), with a mean age of 24.6 (range 17-38) and 23.7 (range 17-33) years old, respectively. Rotator cuff or long head biceps abnormality was found in 36 (33%) players, of which 22 (20%) were either partial or full-thickness tears. Glenoid labral tears were present in 63 (57%) players. There was no significant difference (p > 0.05) in the frequency of tears of the superior (24%), anterior inferior (25%), posterior superior (25%), and posterior inferior (32%) labrum. Forty-seven percent of players presented with two or more abnormalities of the rotator cuff tendons and glenoid labrum. There were significantly more osseous abnormalities in backs compared to forwards (48% vs. 21%; p = 0.01)., Conclusions: There is a wide spectrum of shoulder abnormalities on MRI in professional rugby players, and many have two or more abnormalities. In common with other contact sports, posterior labral injury was a common finding and may relate to sub-clinical trauma, without an association with instability., (© 2024. The Author(s), under exclusive licence to International Skeletal Society (ISS).)
- Published
- 2024
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5. Targeted four-dimensional computerized tomography scans for elbow disorders: a literature review and refinement of existing technique with two exemplar cases.
- Author
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Wong WS, Sim C, Tay ZQ, Yeap PM, and Seah RB
- Abstract
Background: Four-dimensional computerized tomographies (4D-CTs) or motion CTs in elbow disorders have several potential advantages over conventional static imaging such as a reduction of misdiagnoses, a more targeted surgical approach, better patient understanding of their condition and potentially faster operative times. However, the radiation dose is higher than conventional static CT scans so this should be used judiciously. Our study reviews the current literature for 4D-CTs in dynamic elbow disorders and provides a technical note describing radiation-reduced targeted elbow 4D-CTs (te4D-CT) with two exemplar cases alongside our recommendations for when te4D-CTs are indicated., Methods: te4D-CTs are performed in a lateral decubitus elbow above head position. Preliminary static source axial cut CT obtained with subsequent sagittal and axial planes reconstruction and 3D reconstruction obtained, followed by scan performed in motion and reconstructed to 4D Component. te4D-CTs are taken for either flexion and extension (FE) or pronation and supination (PS) motions depending on the clinical pathology suspected following thorough clinical examination., Results: te4D-CT for PS and FE protocol scans had an effective radiation exposure dose of 0.53 and 0.95mSv, respectively, compared to 1.13-1.83 mSv in conventional elbow 4D-CTs. In addition, te4D-CTs have good diagnostic accuracy provided that the FE or PS pathology is identified carefully by the ordering physician., Conclusion: te4D-CT using isolated pronation and supination, or flexion and extension protocols does come with a significantly reduced radiation dose and can be of equal clinical yield compared with 4D-CTs., (© 2023 The Authors.)
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- 2023
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6. Lower leg mass in pulmonary embolism: a case of popliteal vein aneurysm.
- Author
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Wong EJM, Leong S, and Yeap PM
- Subjects
- Humans, Leg, Popliteal Vein diagnostic imaging, Aneurysm diagnostic imaging, Aneurysm surgery, Pulmonary Embolism diagnostic imaging, Pulmonary Embolism therapy
- Abstract
Popliteal vein aneurysms (PVAs) are rare entities, with less than 300 hundred cases reported in the global literature. Despite their rarity, they have immense consequences, having the potential to lead to life-threatening conditions such as pulmonary embolisms and even death. Hence, it is vital for clinicians to be aware of this condition. In this paper, we report a case of PVA and its imaging features seen on the varying imaging modalities. Diagnosis often may not be straightforward as it can mimic other non-vascular or soft tissue masses, hence understanding and appreciating its specific imaging appearances is essential. Generally, PVAs are treated surgically with good outcomes with no reported mortality or recurrence of pulmonary embolism., (© 2022. American Society of Emergency Radiology.)
- Published
- 2022
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7. Posterolateral migration of a sequestrated disc: magnetic resonance imaging findings demystified.
- Author
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Goh WX, Wong SB, Chong AP, and Yeap PM
- Subjects
- Humans, Magnetic Resonance Imaging
- Published
- 2022
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8. Outcomes of Magnetic Resonance Imaging Detected Occult Neck of Femur Fractures: Do They Represent a Less Severe Injury with Improved Outcomes?
- Author
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Raval P, Mayne AIW, Yeap PM, Oliver TB, Jariwala A, and Sripada S
- Abstract
Purpose: Occult hip fractures in the elderly can be missed on standard radiographs and are a known cause of morbidity. These are generally diagnosed on either magnetic resonance imaging (MRI) or computed tomography scan, depending upon local hospital policy. While there is an abundance of literature on hip fractures in general, little is known about the clinical outcome of patients with occult hip fractures. The aim of this study was to review the demographics, injury characteristics, management and clinical outcome of patients diagnosed with occult femoral neck fractures on MRI., Materials and Methods: Using an existing hospital database, a retrospective analysis of all patients with occult hip fractures diagnosed by MRI scan from 2005 to 2014 was conducted., Results: Sixty-four patients (23 males and 41 females) were included. The mean duration of hospitalisation was 16 days. A significantly higher percentage of patients were discharged to their pre-existing residence compared to National Institute for Health and Care Excellence (NICE) commissioning guidelines (66% vs. 45%). The 30- and 60-day mortalities were 3% and 10%, respectively. Mortality was lower in patients who underwent internal fixation (n=3/31) compared with those undergoing replacement (hemi/total hip arthroplasty) (n=5/12) ( P =0.056)., Conclusion: Patients with occult hip fractures diagnosed on an MRI scan are more likely to be discharged to their pre-existing residence and have lower mortality rates compared to NICE guidelines and National Hip Fracture Database (NHFD)., Competing Interests: CONFLICT OF INTEREST: The authors declare that there is no potential conflict of interest relevant to this article.
- Published
- 2019
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9. A comparison of the imaging features of pleomorphic and classical invasive lobular carcinoma.
- Author
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Yeap PM, Evans A, Purdie CA, Jordan LB, and Vinnicombe SJ
- Subjects
- Adult, Aged, Aged, 80 and over, Breast Neoplasms diagnosis, Breast Neoplasms diagnostic imaging, Carcinoma, Ductal, Breast diagnosis, Carcinoma, Ductal, Breast diagnostic imaging, Carcinoma, Lobular diagnosis, Carcinoma, Lobular diagnostic imaging, Diagnosis, Differential, Female, Humans, Mammography, Middle Aged, Neoplasm Invasiveness diagnosis, Neoplasm Invasiveness diagnostic imaging, Retrospective Studies, Ultrasonography, Mammary, Breast Neoplasms pathology, Carcinoma, Ductal, Breast pathology, Carcinoma, Lobular pathology, Neoplasm Invasiveness pathology
- Abstract
Purpose: Pleomorphic invasive lobular carcinoma (pILC) is a distinct morphological variant of ILC with a poorer prognosis than classical ILC (cILC). The aim of this study was to ascertain whether the conventional imaging appearances of the two entities differ., Methods: A single-center retrospective review of conventional imaging was undertaken in 150 consecutive patients with histopathologically confirmed ILC (38 pILC; 112 cILC) between April 2010 and July 2015. Mammographic and sonographic findings were evaluated using the BI-RADS lexicon by a radiologist blinded to pathology, and the findings in the two groups were compared. The degree of discrepancy between imaging and pathological sizing in the two groups was evaluated., Results: Lesions were mammographically occult in 11% of pILC and 14% of cILC (p = 0.56). On mammography, skin or trabecular thickening and microcalcification were commoner in pILC than cILC (13% vs. 1%, p < 0.01; 25% vs. 5%, p < 0.01). Architectural distortion was more frequent in cILC than pILC (26% vs. 9%, p = 0.01). On ultrasound, pILC more frequently exhibited mixed echogenicity (28% vs. 13%; p = 0.04), skin thickening, subcutaneous or parenchymal edema (8% vs. 0%; p = 0.02), echogenic surrounding fat (33% vs. 9%; p < 0.01), and posterior acoustic enhancement (10% vs. 1%; p = 0.02) than cILC. CILC was more frequently manifested as a focal area of altered echogenicity (24% vs. 8%; p = 0.04). Mean elastography stiffness was higher for pILC (174.8 vs. 124.6 kPa; p = 0.02). Imaging-pathological size disparity was similar for both subtypes., Conclusion: There are differences in the imaging features between pILC and cILC which reflect the more aggressive nature of pILC.
- Published
- 2018
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10. Ultrasound Diagnostic and Therapeutic Injections of the Hip and Groin.
- Author
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Yeap PM and Robinson P
- Abstract
Hip and groin pain often presents a diagnostic and therapeutic challenge. The differential diagnosis is extensive, comprising intra-articular and extra-articular pathology and referred pain from lumbar spine, knee and elsewhere in the pelvis. Various ultrasound-guided techniques have been described in the hip and groin region for diagnostic and therapeutic purposes. Ultrasound has many advantages over other imaging modalities, including portability, lack of ionising radiation and real-time visualisation of soft tissues and neurovascular structures. Many studies have demonstrated the safety, accuracy and efficacy of ultrasound-guided techniques, although there is lack of standardisation regarding the injectates used and long-term benefit remains uncertain.
- Published
- 2017
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11. Evidence-based anatomical review areas derived from systematic analysis of cases from a radiological departmental discrepancy meeting.
- Author
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Chin SC, Weir-McCall JR, Yeap PM, White RD, Budak MJ, Duncan G, Oliver TB, and Zealley IA
- Subjects
- Abdomen diagnostic imaging, Central Nervous System diagnostic imaging, Humans, Musculoskeletal System diagnostic imaging, Pelvis diagnostic imaging, Retrospective Studies, Thorax diagnostic imaging, Diagnostic Errors statistics & numerical data, Diagnostic Imaging standards, Evidence-Based Medicine, Radiology standards, Radiology Department, Hospital standards
- Abstract
Aim: To produce short checklists of specific anatomical review sites for different regions of the body based on the frequency of radiological errors reviewed at radiology discrepancy meetings, thereby creating "evidence-based" review areas for radiology reporting., Materials and Methods: A single centre discrepancy database was retrospectively reviewed from a 5-year period. All errors were classified by type, modality, body system, and specific anatomical location. Errors were assigned to one of four body regions: chest, abdominopelvic, central nervous system (CNS), and musculoskeletal (MSK). Frequencies of errors in anatomical locations were then analysed., Results: There were 561 errors in 477 examinations; 290 (46%) errors occurred in the abdomen/pelvis, 99 (15.7%) in the chest, 117 (18.5%) in the CNS, and 125 (19.9%) in the MSK system. In each body system, the five most common location were chest: lung bases on computed tomography (CT), apices on radiography, pulmonary vasculature, bones, and mediastinum; abdominopelvic: vasculature, colon, kidneys, liver, and pancreas; CNS: intracranial vasculature, peripheral cerebral grey matter, bone, parafalcine, and the frontotemporal lobes surrounding the Sylvian fissure; and MSK: calvarium, sacrum, pelvis, chest, and spine., Conclusion: The five listed locations accounted for >50% of all perceptual errors suggesting an avenue for focused review at the end of reporting., (Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2017
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12. Reply: The Enigma of Left Ventricular Non-Compaction.
- Author
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Weir-McCall JR, Yeap PM, Papagiorcopulo C, Fitzgerald K, Gandy SJ, Lambert M, Belch JJF, Cavin I, Littleford R, Macfarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan F, Henderson SA, White RD, and Houston JG
- Subjects
- Female, Heart Ventricles, Humans, Pregnancy, Isolated Noncompaction of the Ventricular Myocardium, Sports
- Published
- 2017
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13. Left Ventricular Noncompaction: Anatomical Phenotype or Distinct Cardiomyopathy?
- Author
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Weir-McCall JR, Yeap PM, Papagiorcopulo C, Fitzgerald K, Gandy SJ, Lambert M, Belch JJ, Cavin I, Littleford R, Macfarlane JA, Matthew SZ, Nicholas RS, Struthers AD, Sullivan F, Waugh SA, White RD, and Houston JG
- Subjects
- Adult, Diagnosis, Differential, Echocardiography, Female, Humans, Male, Middle Aged, Phenotype, Retrospective Studies, Cardiomyopathies diagnosis, Heart Ventricles diagnostic imaging, Isolated Noncompaction of the Ventricular Myocardium diagnosis, Magnetic Resonance Imaging, Cine methods
- Abstract
Background: There is considerable overlap between left ventricular noncompaction (LVNC) and other cardiomyopathies. LVNC has been reported in up to 40% of the general population, raising questions about whether it is a distinct pathological entity, a remodeling epiphenomenon, or merely an anatomical phenotype., Objectives: The authors determined the prevalence and predictors of LVNC in a healthy population using 4 cardiac magnetic resonance imaging diagnostic criteria., Methods: Volunteers >40 years of age (N = 1,651) with no history of cardiovascular disease (CVD), a 10-year risk of CVD < 20%, and a B-type natriuretic peptide level greater than their gender-specific median underwent magnetic resonance imaging scan as part of the TASCFORCE (Tayside Screening for Cardiac Events) study. LVNC ratios were measured on the horizontal and vertical long axis cine sequences. All individuals with a noncompaction ratio of ≥2 underwent short axis systolic and diastolic LVNC ratio measurements, and quantification of noncompacted and compacted myocardial mass ratios. Those who met all 4 criteria were considered to have LVNC., Results: Of 1,480 participants analyzed, 219 (14.8%) met ≥1 diagnostic criterion for LVNC, 117 (7.9%) met 2 criteria, 63 (4.3%) met 3 criteria, and 19 (1.3%) met all 4 diagnostic criteria. There was no difference in demographic or allometric measures between those with and without LVNC. Long axis noncompaction ratios were the least specific, with current diagnostic criteria positive in 219 (14.8%), whereas the noncompacted to compacted myocardial mass ratio was the most specific, only being met in 61 (4.4%)., Conclusions: A significant proportion of an asymptomatic population free from CVD satisfy all currently used cardiac magnetic resonance imaging diagnostic criteria for LVNC, suggesting that those criteria have poor specificity for LVNC, or that LVNC is an anatomical phenotype rather than a distinct cardiomyopathy., (Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
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14. High-Resolution Microscopy-Coil MR Imaging of Skin Tumors: Techniques and Novel Clinical Applications.
- Author
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Budak MJ, Weir-McCall JR, Yeap PM, White RD, Waugh SA, Sudarshan TA, and Zealley IA
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- Equipment Design, Humans, Reproducibility of Results, Sensitivity and Specificity, Dermoscopy instrumentation, Image Enhancement instrumentation, Magnetic Resonance Imaging instrumentation, Microscopy instrumentation, Multimodal Imaging instrumentation, Skin Neoplasms pathology
- Abstract
High-resolution magnetic resonance (MR) imaging performed with a microscopy coil is a robust radiologic tool for the evaluation of skin lesions. Microscopy-coil MR imaging uses a small surface coil and a 1.5-T or higher MR imaging system. Simple T1- and T2-weighted imaging protocols can be implemented to yield high-quality, high-spatial-resolution images that provide an excellent depiction of dermal anatomy. The primary application of microscopy-coil MR imaging is to delineate the deep margins of skin tumors, thereby providing a preoperative road map for dermatologic surgeons. This information is particularly useful for surgeons who perform Mohs micrographic surgery and in cases of nasofacial neoplasms, where the underlying anatomy is complex. Basal cell carcinoma is the most common nonmelanocytic skin tumor and has a predilection to manifest on the face, where it can be challenging to achieve complete surgical excision while preserving the cosmetic dignity of the patient. Microscopy-coil MR imaging provides dermatologic surgeons with valuable preoperative anatomic information that is not available at conventional clinical examination., (©RSNA, 2015.)
- Published
- 2015
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15. Authors' Response.
- Author
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Budak MJ, Weir-McCall JR, Yeap PM, Sudarshan TA, Zealley IA, Waugh SA, and White RD
- Subjects
- Humans, Dermoscopy instrumentation, Image Enhancement instrumentation, Magnetic Resonance Imaging instrumentation, Microscopy instrumentation, Multimodal Imaging instrumentation, Skin Neoplasms pathology
- Published
- 2015
16. The celiac axis revisited: anatomic variants, pathologic features, and implications for modern endovascular management.
- Author
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White RD, Weir-McCall JR, Sullivan CM, Mustafa SA, Yeap PM, Budak MJ, Sudarshan TA, and Zealley IA
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- Humans, Angiography methods, Celiac Artery anatomy & histology, Celiac Artery pathology, Endovascular Procedures, Magnetic Resonance Angiography methods, Ultrasonography methods, Vascular Diseases diagnosis, Vascular Diseases therapy, Viscera blood supply
- Abstract
The celiac axis (CA) and its branches are critically important arteries that supply blood to the vital solid and hollow abdominal viscera of the foregut. There are many potential anatomic configurations, with up to half the population having a variation from the classic pattern of the CA bifurcating into the hepatosplenic trunk and left gastric artery. These configurations result from permutations in the fusion of the paired dorsal aortas during the first trimester. Despite the short length of the CA, it is affected by a wide range of pathologic conditions, including mesenteric ischemia due to intrinsic occlusion (secondary to causes such as atherosclerosis or thromboembolic events) and extrinsic compression from masses or the median arcuate ligament. Symptoms of mesenteric ischemia are nonspecific and include postprandial abdominal pain and weight loss; thus, the underlying pathologic condition may be found only when being sought specifically. More unusual pathologic conditions include dissection, aneurysms, and vascular malformations. Awareness of the pathologic conditions that affect the CA is important for both diagnostic and interventional radiologists. Early recognition and treatment of CA disease may prevent catastrophic hemorrhage and bowel infarction. Both endovascular and surgical approaches to treatment are greatly enhanced by correct identification of arterial anatomic variants; catheter angiography, computed tomographic angiography, and magnetic resonance angiography can facilitate detection of these variants. Knowledge of the different anatomic permutations is essential to guide endovascular procedures, such as hemorrhage control, transarterial interventional oncologic therapy, and treatment of visceral artery aneurysms. Online supplemental material is available for this article., ((©)RSNA, 2015.)
- Published
- 2015
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17. Visible thyroid ectopia.
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Yeap PM, Attaie M, Jones J, Maroo S, and Donaldson M
- Subjects
- Humans, Infant, Newborn, Male, Thyroid Gland diagnostic imaging, Ultrasonography, Congenital Hypothyroidism diagnosis, Thyroid Dysgenesis diagnosis, Thyroid Gland abnormalities
- Published
- 2012
- Full Text
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18. Molecular analysis of pheochromocytoma after maternal transmission of SDHD mutation elucidates mechanism of parent-of-origin effect.
- Author
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Yeap PM, Tobias ES, Mavraki E, Fletcher A, Bradshaw N, Freel EM, Cooke A, Murday VA, Davidson HR, Perry CG, and Lindsay RS
- Subjects
- Alleles, Chromosomes, Human, Pair 11, DNA Mutational Analysis, Female, Humans, Loss of Heterozygosity, Male, Pedigree, Adrenal Gland Neoplasms genetics, Germ-Line Mutation, Pheochromocytoma genetics, Succinate Dehydrogenase genetics
- Abstract
Context: Pheochromocytoma/paraganglioma occurs almost exclusively after paternal transmission of succinate dehydrogenase D (SDHD) mutations. This parent-of-origin effect has not been fully explained but is accompanied by obligate loss of the maternal copy of chromosome 11. Loss of wild-type SDHD and an additional imprinted gene (hypothesized to be H19) appears necessary for tumor formation. Two previous reports suggested tumor formation after maternal transmission of SDHD mutation, but histological and molecular characterization was unavailable., Objective: We report the first kindred in which histologically confirmed pheochromocytoma/paraganglioma occurred after maternal transmission of an SDHD mutation and investigate the molecular mechanism of tumor formation., Design: The design of the investigation was the study of a three-generation family with SDHD c.242C>T (p.Pro81Leu) mutation., Results: The index patient had a histologically confirmed pheochromocytoma and an identical SDHD germline mutation (p.Pro81Leu) to her mother (who had a glomus jugulare tumor) and paraganglioma tissue from her maternal grandfather. Tumor DNA from the index patient revealed loss of heterozygosity (LOH) at 11q23, causing loss of the wild-type paternal SDHD allele and LOH affecting maternal 11p15, including H19. These two regions of LOH were separated by a region exhibiting clearly retained heterozygosity, including SDHAF2, a recently reported paraganglioma susceptibility gene., Conclusions: Tumor formation can occur after maternal transmission of SDHD, a finding with important clinical implications for SDHD families. Tumor formation in SDHD mutation requires the loss of both the wild-type SDHD allele and maternal 11p15, leading to the predominant but now not exclusive pattern of disease inheritance after paternal SDHD transmission.
- Published
- 2011
- Full Text
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19. A small left pupil and a headache.
- Author
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Yeap PM, Tziotzios C, McMillan N, and Walters M
- Subjects
- Carotid Artery, Internal, Dissection therapy, Humans, Male, Young Adult, Carotid Artery, Internal, Dissection complications, Carotid Artery, Internal, Dissection diagnosis, Headache etiology, Pupil Disorders etiology
- Published
- 2011
- Full Text
- View/download PDF
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