Search

Your search keyword '"Ye, Wenyuan"' showing total 136 results
Start Over Author "Ye, Wenyuan"
136 results on '"Ye, Wenyuan"'

29. Shielding effect enables ultrafast ion transfer through nanoporous membrane for highly energy-efficient electrodialysis

Author

Lin, Jiuyang, primary, Ye, Wenyuan, additional, Xie, Shuangling, additional, Du, Jiale, additional, Liu, Riri, additional, Zou, Dong, additional, Chen, Xiangyu, additional, Yu, Zijian, additional, Fang, Shengqiong, additional, Ang, Elisa Yun Mei, additional, Toh, William, additional, Han, Dan Dan, additional, Ng, Teng Yong, additional, Seo, Dong Han, additional, Zhao, Shuaifei, additional, Bruggen, Bart Van der, additional, Xie, Ming, additional, and Lee, Young Moo, additional

Published
2022
Full Text
View/download PDF

35. Electron microscopic structure of purified, active [gamma]-secretase reveals an aqueous intramembrane chamber and two pores

Author

Lazarov, Vlado K., Fraering, Patrick C., Ye, Wenyuan, Wolfe, Michael S., Selkoe, Dennis J., and Li, Huilin

Subjects
Electron microscopy -- Research, Proteases -- Research, Science and technology
Abstract

[gamma]-Secretase is an intramembrane-cleaving aspartyl protease required for the normal development of metazoans because it processes Notch within cellular membranes to release its signaling domain. More than two dozen additional substrates of diverse functions have been reported, including the Notch ligands Delta and Jagged, N- and E-cadherins, and a sodium channel subunit. The protease is causally implicated in Alzheimer's disease because it releases the neurotoxic amyloid [beta]-peptide (A[beta]) from its precursor, APP. [gamma]-Secretase occurs as a large complex containing presenilin (bearing the active site aspartates), nicastrin, Aph-1, and Pen-2. Because the complex contains at least 18 transmembrane domains, crystallographic approaches to its structure are difficult and remote. We recently purified the human complex essentially to homogeneity from stably expressing mammalian cells. Here, we use EM and single-particle image analysis on the purified enzyme, which produces physiological ratios of A[beta]40 and A[beta]42, to obtain structural information on an intramembrane protease. The 3D EM structure revealed a large, cylindrical interior chamber of ~20-40 A in length, consistent with a proteinaceous proteolytic site that is occluded from the hydrophobic environment of the lipid bilayer. Lectin tagging of the nicastrin ectodomain enabled proper orientation of the globular, ~120-[Angstrom]-long complex within the membrane and revealed -20-[Angstrom] pores at the top and bottom that provide potential exit ports for cleavage products to the extra- and intracellular compartments. Our reconstructed 3D map provides a physical basis for hydrolysis of transmembrane substrates within a lipid bilayer and release of the products into distinct subcellular compartments. electron microscopy | image analysis | intramembrane protease

Published
2006

45. Potential of coagulation/GAC adsorption combined with UV/H2O2 and ozonation for removing dissolved organic matter from secondary RO concentrate.

Author

Zhang, Xian, Lin, Jiuyang, Ye, Wenyuan, Zhou, Wei, Jia, Xuxiang, Zhao, Shuaifei, and Ye, Chunsong

Subjects
OZONIZATION, DISSOLVED organic matter
Abstract

BACKGROUD Organic contaminants in secondary reverse osmosis (SRO) concentrate pose a severe threat to the ecosystem, due to their potential toxicity. In this study, potential of coagulation/granular activated carbon (GAC) adsorption combined with UV/H2O2 and ozonation for removing organic matter from industrial secondary RO concentrate was systematically investigated. RESULTS: Coagulation with 2.0 mmol L−1 FeCl3 yielded 40% removal of dissolved organic carbon (DOC), while adsorption with 5 g L−1 GAC could boost the removal efficiency up to 78.2%. Fractionation results showed that both coagulation and GAC adsorption favored hydrophobic organics. UV/H2O2 oxidation was capable of removing 87.4% of DOC, which outperformed ozonation (58.2%). UV/H2O2 and ozonation showed similar behavior in dissolved organic matter (DOM) degradation: a portion of hydrophobic organics were first transformed into hydrophilic fractions prior to final mineralization. Conclusion: Coupling of GAC as post‐treatment with a UV/H2O2 process yielded 97.9% removal of DOC and the corresponding electrical energy per order (EE/O) was decreased from 66.7 to 35.8 kWh m−3. Consequently, a simple UV/H2O2 and GAC hybrid process was proposed to be a suitable method for removing DOM from SRO concentrate. © 2018 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

46. High-flux nanofiltration membranes tailored by bio-inspired co-deposition of hydrophilic g-C3N4nanosheets for enhanced selectivity towards organics and saltsElectronic supplementary information (ESI) available. See DOI: 10.1039/c9en00692c

Author

Ye, Wenyuan, Liu, Hongwei, Lin, Fang, Lin, Jiuyang, Zhao, Shuaifei, Yang, Shishi, Hou, Jingwei, Zhou, Shungui, and Van der Bruggen, Bart

Abstract

Surface modification with advanced nanomaterials (i.e., 2D nanosheets) can be used to strategically tailor membrane properties, providing improved solute permselectivity to targeted molecules. In particular, 2D graphite-like carbon nitride (g-C3N4) nanosheets are a promising alternative for membrane modification, due to their exceptional physicochemical properties and facile synthesis. Herein, high-flux nanofiltration (NF) membranes were designed using bio-inspired co-deposition of hydrophilic g-C3N4nanosheets with a polydopamine (PDA)/polyethylenimine (PEI) layer onto porous ultrafiltration (UF) substrates. The g-C3N4nanosheets created additional nanochannels in the PDA/PEI layer to facilitate water molecule transport, resulting in high permeability (28.4 ± 1.2 L m−2h−1bar−1). Particularly, the bio-inspired layer structure was tailored from the UF to the NF (592 Da) scale by incorporating g-C3N4nanosheets, thereby breaking through the permeability–selectivity trade-off effect. The tailored NF membrane enabled ultrahigh retention of three reactive dyes (610–630 Da, >99.3%) and low salt rejection (2.9% for NaCl; 7.6% for Na2SO4), significantly promoting the fractionation of dyes and salts for dye desalination. Additionally, the hydrophilic g-C3N4nanosheets with oxygen plasma treatment further enhanced the wettability of the membrane surfaces, resulting in a superior antifouling performance. This study indicates the promise of g-C3N4nanosheets to engineer high-flux NF membranes with desirable fractionation performance for sustainable treatment of highly saline wastewater.

Published
2019
Full Text
View/download PDF

47. Toward Resource Recovery from Textile Wastewater: Dye Extraction, Water and Base/Acid Regeneration Using a Hybrid NF-BMED Process

Author

Lin, Jiuyang, primary, Ye, Wenyuan, additional, Huang, Jie, additional, Ricard, Borrego, additional, Baltaru, Marian-Cornel, additional, Greydanus, Benjamin, additional, Balta, Stefan, additional, Shen, Jiangnan, additional, Vlad, Maria, additional, Sotto, Arcadio, additional, Luis, Patricia, additional, and Van der Bruggen, Bart, additional

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results