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26 results on '"Ye, Tianyang"'

2. 3D spatiotemporally scalable in vivo neural probes based on fluorinated elastomers

Author

Le Floch, Paul, Zhao, Siyuan, Liu, Ren, Molinari, Nicola, Medina, Eder, Shen, Hao, Wang, Zheliang, Kim, Junsoo, Sheng, Hao, Partarrieu, Sebastian, Wang, Wenbo, Sessler, Chanan, Zhang, Guogao, Park, Hyunsu, Gong, Xian, Spencer, Andrew, Lee, Jongha, Ye, Tianyang, Tang, Xin, Wang, Xiao, Bertoldi, Katia, Lu, Nanshu, Kozinsky, Boris, Suo, Zhigang, and Liu, Jia

Published
2024
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5. 3D spatiotemporally scalable in vivo neural probes based on fluorinated elastomers

Author

Le Floch, Paul, primary, Zhao, Siyuan, additional, Liu, Ren, additional, Molinari, Nicola, additional, Medina, Eder, additional, Shen, Hao, additional, Wang, Zheliang, additional, Kim, Junsoo, additional, Sheng, Hao, additional, Partarrieu, Sebastian, additional, Wang, Wenbo, additional, Sessler, Chanan, additional, Zhang, Guogao, additional, Park, Hyunsu, additional, Gong, Xian, additional, Spencer, Andrew, additional, Lee, Jongha, additional, Ye, Tianyang, additional, Tang, Xin, additional, Wang, Xiao, additional, Bertoldi, Katia, additional, Lu, Nanshu, additional, Kozinsky, Boris, additional, Suo, Zhigang, additional, and Liu, Jia, additional

Published
2023
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13. Parameters Optimization for Catalyst Centrifugal Spray Drying Process Based on BP Neural Network and Genetic Algorithm

Author

Jingjing Xu, Ye Tianyang, and Liu Yunfei

Subjects
Materials science, Artificial neural network, business.industry, Industrial production, 04 agricultural and veterinary sciences, 02 engineering and technology, 040401 food science, Catalysis, 0404 agricultural biotechnology, 020401 chemical engineering, Fine powder, Scientific method, Spray drying, Genetic algorithm, 0204 chemical engineering, Process engineering, business
Abstract

Reasonable and effective process parameters in the catalyst centrifugal spray drying are of significance for the quality and industrial production of the catalyst. The overall desirability of fine powder ratio and water evaporation is defined as the goal and the process parameters are optimized based on BP neural network with genetic algorithm, which obtains the better drying performance. The optimization results provide a basis for setting the process parameters of the industrial production of catalyst centrifugal spray drying and improve the quality of the catalyst product.

Published
2019

20. Optimizing Nanoelectrode Arrays for Scalable Intracellular Electrophysiology

Author

Abbott, Jeffrey, Ye, Tianyang, Ham, Donhee, and Park, Hongkun

Abstract

Electrode technology for electrophysiology has a long history of innovation, with some decisive steps including the development of the voltage-clamp measurement technique by Hodgkin and Huxley in the 1940s and the invention of the patch clamp electrode by Neher and Sakmann in the 1970s. The high-precision intracellular recording enabled by the patch clamp electrode has since been a gold standard in studying the fundamental cellular processes underlying the electrical activities of neurons and other excitable cells. One logical next step would then be to parallelize these intracellular electrodes, since simultaneous intracellular recording from a large number of cells will benefit the study of complex neuronal networks and will increase the throughput of electrophysiological screening from basic neurobiology laboratories to the pharmaceutical industry. Patch clamp electrodes, however, are not built for parallelization; as for now, only ∼10 patch measurements in parallel are possible.

Published
2024
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25. Gate-Modulated Photoresponse in Graphene Field-Effect Transistors

Author

Wei, Zijun, Wang, Zhigang, Zhao, Huabo, Ye, Tianyang, Ren, Liming, Guo, Jian, Jia, Yuehui, Zhang, Zhaohui, Fu, Yunyi, Huang, Ru, and Zhang, Xing

Abstract

In this paper, we have investigated the photoresponse in a graphene field-effect transistor (FET). We find that significant photocurrents can be detected when the device is illuminated by a laser beam (λ = 633nm). The back-gate can effectively modulate the magnitude and direction of the photocurrent. The possible reasons have been qualitatively analyzed. Our results will provide a better understanding of the electric field distribution in graphene devices, and may also be helpful to find a new way to realize the graphene-based photodetectors.

Published
2013
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26. Optimizing Nanoelectrode Arrays for Scalable Intracellular Electrophysiology.

Author

Abbott J, Ye T, Ham D, and Park H

Subjects
Animals, Cell Line, Cell Membrane chemistry, Cell Membrane metabolism, Electrodes, Humans, B-Lymphocytes metabolism, Electrophysiological Phenomena, Myocytes, Cardiac metabolism, Nanoparticles chemistry, Neurons metabolism
Abstract

Electrode technology for electrophysiology has a long history of innovation, with some decisive steps including the development of the voltage-clamp measurement technique by Hodgkin and Huxley in the 1940s and the invention of the patch clamp electrode by Neher and Sakmann in the 1970s. The high-precision intracellular recording enabled by the patch clamp electrode has since been a gold standard in studying the fundamental cellular processes underlying the electrical activities of neurons and other excitable cells. One logical next step would then be to parallelize these intracellular electrodes, since simultaneous intracellular recording from a large number of cells will benefit the study of complex neuronal networks and will increase the throughput of electrophysiological screening from basic neurobiology laboratories to the pharmaceutical industry. Patch clamp electrodes, however, are not built for parallelization; as for now, only ∼10 patch measurements in parallel are possible. It has long been envisioned that nanoscale electrodes may help meet this challenge. First, nanoscale electrodes were shown to enable intracellular access. Second, because their size scale is within the normal reach of the standard top-down fabrication, the nanoelectrodes can be scaled into a large array for parallelization. Third, such a nanoelectrode array can be monolithically integrated with complementary metal-oxide semiconductor (CMOS) electronics to facilitate the large array operation and the recording of the signals from a massive number of cells. These are some of the central ideas that have motivated the research activity into nanoelectrode electrophysiology, and these past years have seen fruitful developments. This Account aims to synthesize these findings so as to provide a useful reference. Summing up from the recent studies, we will first elucidate the morphology and associated electrical properties of the interface between a nanoelectrode and a cellular membrane, clarifying how the nanoelectrode attains intracellular access. This understanding will be translated into a circuit model for the nanobio interface, which we will then use to lay out the strategies for improving the interface. The intracellular interface of the nanoelectrode is currently inferior to that of the patch clamp electrode; reaching this benchmark will be an exciting challenge that involves optimization of electrode geometries, materials, chemical modifications, electroporation protocols, and recording/stimulation electronics, as we describe in the Account. Another important theme of this Account, beyond the optimization of the individual nanoelectrode-cell interface, is the scalability of the nanoscale electrodes. We will discuss this theme using a recent development from our groups as an example, where an array of ca. 1000 nanoelectrode pixels fabricated on a CMOS integrated circuit chip performs parallel intracellular recording from a few hundreds of cardiomyocytes, which marks a new milestone in electrophysiology.

Published
2018
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