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45 results on '"Ye, Q. H."'

2. Transtracheal ultrasound for confirmation of endotracheal tube placement in the intensive care unit: a systematic review and meta-analysis.

Author

CHEN, W.-T., WANG, M.-Y., JIANG, T.-T., TANG, M., YE, Q.-H., WANG, H.-Y., and MO, E.-J.

Abstract

OBJECTIVE: The major objective of this review was to compare the diagnostic accuracy of ultrasound in confirming tracheal intubation to the standard methods of confirmation in the intensive care unit (ICU). MATERIALS AND METHODS: This systematic review and meta-analysis of observational studies was conducted from inception to July 2022. We included studies that compared the diagnostic accuracy of ultrasound-detected tracheal intubation to that of the gold standard diagnostic technique performed in adult patients who underwent tracheal intubation as part of any procedure. We searched the following electronic databases for published studies: PubMed, EMBASE, Cochrane Central, and Web of Science. Risk of bias was assessed using a standard procedure based on the Quality Assessment of Diagnostic Accuracy Studies-2 criteria. The results were analyzed using the RevMan or Meta-Disc software to determine the adequacy and conclusiveness of the available evidence. RESULTS: Five studies that included 344 patients met the inclusion criteria. Pooled sensitivity was 0.96 (95% confidence interval (CI) (0.92- 0.98) and 1.00 (95% CI: 0.97-1.00), respectively. Furthermore, the diagnostic odds ratio of ultrasonography was 311.25 (95% CI: 63.77-1,519.22), which was confirmed by a summary receiver operating characteristic curve with an area under the curve of 0.98. CONCLUSIONS: Ultrasonography has high sensitivity and specificity, is a valuable adjunct for confirming tracheal intubation in the ICU and should be performed when capnography is unavailable or unreliable. [ABSTRACT FROM AUTHOR]

Published
2022

3. The diagnostic values of lung ultrasound for ARDS.

Author

CHEN, W.-T., WANG, H.-Y., YE, Q.-H., TANG, M., and WANG, Y.-W.

Abstract

OBJECTIVE: Acute respiratory distress syndrome (ARDS) is a critical disease commonly found in many clinical cases, with a mortality rate of approximately 50%. Early diagnosis and intervention are important for improving ARDS prognosis. In this study, the applications of lung ultrasound in ARDS diagnosis and assessment are reviewed to clarify its key clinical values and application prospects. MATERIALS AND METHODS: According to the standard diagnosis of ARDS based on the Berlin definition, CXR or CT examination should be conducted. However, both the blurred images of the former, as well as the inconvenience and high risks of the latter, impose restrictions on their application in critically ill patients. RESULTS: Lung ultrasound was shown to improve safety, effectiveness, lacked radiation, can be performed bedside, and offers dynamic functionality. CONCLUSIONS: It may be a suitable approach to replace or complement traditional imaging examinations with lung ultrasound. [ABSTRACT FROM AUTHOR]

Published
2022

4. Diagnostic accuracy of ultrasonography for detecting gastric tube placement: an updated meta-analysis.

Author

PENG, J., TANG, M., LIU, L.-L., CHEN, W.-T., and YE, Q.-H.

Abstract

OBJECTIVE: This study aimed at reviewing the diagnostic accuracy of ultrasonography for detecting correct nasogastric tube placement compared with X-ray imaging as the reference standard. MATERIALS AND METHODS: This was a systematic review and meta-analysis of observational studies published between 1961 and 2022. We included studies that compared the diagnostic accuracy of ultrasound detection for nasogastric tube placement with that of X-ray imaging in adult patients who were undergoing nasogastric tube placement for any reason. We searched for published studies in the following electronic databases: Cochrane Library, PubMed, EMBASE, and Web of Science. The risk of bias was assessed using a standard procedure according to the Quality Assessment of Diagnostic Accuracy Studies-2 criteria. The results were analyzed using RevMan or Meta-Disc software to determine the adequacy and conclusiveness of the available evidence. RESULTS: Fourteen studies met our inclusion criteria. Overall, 1,812 patients were included in these studies. The results included a pooled sensitivity of 0.96 (95% confidence interval [CI] 0.94-0.97), specificity of 0.91 (95% CI 0.85-0.96), positive likelihood ratio of 5.08 (95% CI 1.49-17.39), and negative likelihood ratio of 0.08 (95% CI 0.06-0.10). This was confirmed through a summary receiver operating characteristic curve, which showed that the area under the curve was 0.96. CONCLUSIONS: We found evidence about validity of ultrasound as an efficient method for verifying nasogastric tube placement, although there is insufficient evidence to suggest that it can be used as a diagnostic tool for incorrect gastric tube placement. [ABSTRACT FROM AUTHOR]

Published
2022

9. Evaluation of the Antibacterial Activity and Probiotic Potential of Lactobacillus plantarum Isolated from Chinese Homemade Pickles

Author

Zeng, Y., primary, Li, Y., additional, Wu, Q. P., additional, Zhang, J. M., additional, Xie, X. Q., additional, Ding, Y., additional, Cai, S. Z., additional, Ye, Q. H., additional, Chen, M. T., additional, Xue, L., additional, Wu, S., additional, Zeng, H. Y., additional, Yang, X. J., additional, and Wang, J., additional

Published
2020
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12. Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station

Author

Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. J., Chang, Y. H., Chen, Andrew I., Cheng, G. M., Chen, H. S., Cheng, L., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Galaktionov, Y., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Haas, D., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Levi, G., Li, H. L., Li, J. Q., Li, Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lolli, M., Lomtadze, T., Lu, M. J., Lu, S. Q., Lu, Y. S., Luebelsmeyer, K., Luo, J. Z., Lv, S. S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X. M., Qin, X., Qu, Z. Y., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, X. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Sun, W., Sun, W. H., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Vitale, V., Vitillo, S., Wang, L. Q., Wang, N. H., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, M., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Yang, J., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Zurbach, C., Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Plyaskin, Vasily, Rozhkov, Andrey B., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xu, Weiwei, Yan, Qi, Zuccon, Paolo, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AMS, Azzarello, Philipp, Bourquin, Maurice, Cadoux, Franck, Cortina Gil, Eduardo, Haas, Daniel, Habiby Alaoui, Marion, Leluc, Catherine, Li, Yang, Paniccia, Mercedes, Pohl, Martin, Rapin, Divic Jean, Saouter, Pierre, Vitillo, Stefania, Wu, Xin, UCL - SST/IRMP - Institut de recherche en mathématique et physique, Aguilar, M, Aisa, D, Alpat, B, Alvino, A, Ambrosi, G, Andeen, K, Arruda, L, Attig, N, Azzarello, P, Bachlechner, A, Barao, F, Barrau, A, Barrin, L, Bartoloni, A, Basara, L, Battarbee, M, Battiston, R, Bazo, J, Becker, U, Behlmann, M, Beischer, B, Berdugo, J, Bertucci, B, Bigongiari, G, Bindi, V, Bizzaglia, S, Bizzarri, M, Boella, G, de Boer, W, Bollweg, K, Bonnivard, V, Borgia, B, Borsini, S, Boschini, M, Bourquin, M, Burger, J, Cadoux, F, Cai, X, Capell, M, Caroff, S, Casaus, J, Cascioli, V, Castellini, G, Cernuda, I, Cerreta, D, Cervelli, F, Chae, M, Chang, Y, Chen, A, Chen, H, Cheng, G, Cheng, L, Chou, H, Choumilov, E, Choutko, V, Chung, C, Clark, C, Clavero, R, Coignet, G, Consolandi, C, Contin, A, Corti, C, Gil, E, Coste, B, Creus, W, Crispoltoni, M, Cui, Z, Dai, Y, Delgado, C, Della Torre, S, Demirköz, M, Derome, L, Di Falco, S, Di Masso, L, Dimiccoli, F, Díaz, C, von Doetinchem, P, Donnini, F, Du, W, Duranti, M, D’Urso, D, Eline, A, Eppling, F, Eronen, T, Fan, Y, Farnesini, L, Feng, J, Fiandrini, E, Fiasson, A, Finch, E, Fisher, P, Galaktionov, Y, Gallucci, G, García, B, García López, R, Gargiulo, C, Gast, H, Gebauer, I, Gervasi, M, Ghelfi, A, Gillard, W, Giovacchini, F, Goglov, P, Gong, J, Goy, C, Grabski, V, Grandi, D, Graziani, M, Guandalini, C, Guerri, I, Guo, K, Haas, D, Habiby, M, Haino, S, Han, K, He, Z, Heil, M, Hoffman, J, Hsieh, T, Huang, Z, Huh, C, Incagli, M, Ionica, M, Jang, W, Jinchi, H, Kanishev, K, Kim, G, Kim, K, Kirn, T, Kossakowski, R, Kounina, O, Kounine, A, Koutsenko, V, Krafczyk, M, LA VACCA, G, Laudi, E, Laurenti, G, Lazzizzera, I, Lebedev, A, Lee, H, Lee, S, Leluc, C, Levi, G, Li, H, Li, J, Li, Q, Li, T, Li, W, Li, Y, Li, Z, Lim, S, Lin, C, Lipari, P, Lippert, T, Liu, D, Liu, H, Lolli, M, Lomtadze, T, Lu, M, Lu, S, Lu, Y, Luebelsmeyer, K, Luo, J, Lv, S, Majka, R, Mañá, C, Marín, J, Martin, T, Martínez, G, Masi, N, Maurin, D, Menchaca Rocha, A, Meng, Q, Mo, D, Morescalchi, L, Mott, P, Müller, M, Ni, J, Nikonov, N, Nozzoli, F, Nunes, P, Obermeier, A, Oliva, A, Orcinha, M, Palmonari, F, Palomares, C, Paniccia, M, Papi, A, Pauluzzi, M, Pedreschi, E, Pensotti, S, Pereira, R, Picot Clemente, N, Pilo, F, Piluso, A, Pizzolotto, C, Plyaskin, V, Pohl, M, Poireau, V, Postaci, E, Putze, A, Quadrani, L, Qi, X, Qin, X, Qu, Z, Räihä, T, Rancoita, P, Rapin, D, Ricol, J, Rodríguez, I, Rosier Lees, S, Rozhkov, A, Rozza, D, Sagdeev, R, Sandweiss, J, Saouter, P, Sbarra, C, Schael, S, Schmidt, S, von Dratzig, A, Schwering, G, Scolieri, G, Seo, E, Shan, B, Shan, Y, Shi, J, Shi, X, Shi, Y, Siedenburg, T, Son, D, Spada, F, Spinella, F, Sun, W, Tacconi, M, Tang, C, Tang, X, Tang, Z, Tao, L, Tescaro, D, Ting, S, Tomassetti, N, Torsti, J, Türkoğlu, C, Urban, T, Vagelli, V, Valente, E, Vannini, C, Valtonen, E, Vaurynovich, S, Vecchi, M, Velasco, M, Vialle, J, Vitale, V, Vitillo, S, Wang, L, Wang, N, Wang, Q, Wang, R, Wang, X, Wang, Z, Weng, Z, Whitman, K, Wienkenhöver, J, Wu, H, Wu, X, Xia, X, Xie, M, Xie, S, Xiong, R, Xin, G, Xu, N, Xu, W, Yan, Q, Yang, J, Yang, M, Ye, Q, Yi, H, Yu, Y, Yu, Z, Zeissler, S, Zhang, J, Zhang, M, Zhang, X, Zhang, Z, Zheng, Z, Zhuang, H, Zhukov, V, Zichichi, A, Zimmermann, N, Zuccon, P, Zurbach, C, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xie, M., Xu, Weiwei, Yan, Qi, Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Becker, U., Behlmann, M., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., De Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M.J., Bourquin, M., Burger, J., Cadoux, F., Cai, X.D., Capell, M., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M.J., Chang, Y.H., Chen, A.I., Chen, H., Cheng, G.M., Chen, H.S., Cheng, L., Chou, H.Y., Choumilov, E., Choutko, V., Chung, C.H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y.M., Delgado, C., Della Torre, S., Demirköz, M.B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., Von Doetinchem, P., Donnini, F., Du, W.J., Duranti, M., D'Urso, D., Eline, A., Eppling, F.J., Eronen, T., Fan, Y.Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Fisher, P., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Goglov, P., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K.H., Haas, D., Habiby, M., Haino, S., Han, K.C., He, Z.H., Heil, M., Hoffman, J., Hsieh, T.H., Huang, Z.C., Huh, C., Incagli, M., Ionica, M., Jang, W.Y., Jinchi, H., Kanishev, K., Kim, G.N., Kim, K.S., Kirn, Th., Kossakowski, R., Kounina, O., Kounine, A., Koutsenko, V., Krafczyk, M.S., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lebedev, A., Lee, H.T., Lee, S.C., Leluc, C., Levi, G., Li, H.L., Li, J.Q., Li, T.X., Li, W., Li, Y., Li, Z.H., Li, Z.Y., Lim, S., Lin, C.H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lolli, M., Lomtadze, T., Lu, M.J., Lu, S.Q., Lu, Y.S., Luebelsmeyer, K., Luo, J.Z., Lv, S.S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D.C., Morescalchi, L., Mott, P., Müller, M., Ni, J.Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Plyaskin, V., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X.M., Qin, X., Qu, Z.Y., Räihä, T., Rancoita, P.G., Rapin, D., Ricol, J.S., Rodríguez, I., Rosier-Lees, S., Rozhkov, A., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S.M., Von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E.S., Shan, B.S., Shan, Y.H., Shi, J.Y., Shi, X.Y., Shi, Y.M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Sun, W., Sun, W.H., Tacconi, M., Tang, C.P., Tang, X.W., Tang, Z.C., Tao, L., Tescaro, D., Ting, Samuel C.C., Ting, S.M., Tomassetti, N., Torsti, J., Türkoʇlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vaurynovich, S., Vecchi, M., Velasco, M., Vialle, J.P., Vitale, V., Vitillo, S., Wang, L.Q., Wang, N.H., Wang, Q.L., Wang, R.S., Wang, X., Wang, Z.X., Weng, Z.L., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R.Q., Xin, G.M., Xu, N.S., Xu, W., Yan, Q., Yang, J., Yang, M., Ye, Q.H., Yi, H., Yu, Y.J., Yu, Z.Q., Zeissler, S., Zhang, J.H., Zhang, M.T., Zhang, X.B., Zhang, Z., Zheng, Z.M., Zhuang, H.L., Zhukov, V., Zichichi, A., Zimmermann, N., Zuccon, P., and Zurbach, C.

Subjects
Astrophysics and Astronomy, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Astrophysics::High Energy Astrophysical Phenomena, Dark matter, General Physics and Astronomy, Cosmic ray, Electron, ddc:500.2, 01 natural sciences, Space mission, Nuclear physics, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], FIS/05 - ASTRONOMIA E ASTROFISICA, Physics and Astronomy (all), Rigidity (electromagnetism), Positron, 0103 physical sciences, Alpha Magnetic Spectrometer, ddc:550, AMS, Detectors and Experimental Techniques, 010303 astronomy & astrophysics, Cosmic rays, ComputingMilieux_MISCELLANEOUS, Physics, Spectral index, ta115, 010308 nuclear & particles physics, Spectral density, FIS/01 - FISICA SPERIMENTALE, Proton Flux, Cosmic Rays, Protons, Cosmic Rays, proton flux
Abstract

Physical review letters 114(17), 171103 (2015). doi:10.1103/PhysRevLett.114.171103, Published by APS, College Park, Md.

Published
2015

13. Precision Measurement of the $\left({e}^{+}+{e}^{-}\right)$ Flux in Primary Cosmic Rays from 0.5 GeV to 1 TeV with the Alpha Magnetic Spectrometer on the International Space Station

Author

Aguilar, M., Aisa, D., Barao, F., Giovacchini, F., Goglov, P., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Barrau, A., Habiby, M., Haino, S., Han, K. C., He, Z. H., Heil, M., Hoffman, J., Hsieh, T. H., Huang, Z. C., Huh, C., Incagli, M., Barrin, L., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., Kounina, O., Kounine, A., Bartoloni, A., Koutsenko, V., Krafczyk, M. S., Kunz, S., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lebedev, A., Lee, H. T., Lee, S. C., Basara, L., Leluc, C., Li, H. L., Li, J. Q., Li, Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Battarbee, M., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lomtadze, T., Lu, M. J., Lu, Y. S., Luebelsmeyer, K., Battiston, R., Luo, F., Luo, J. Z., Lv, S. S., Majka, R., Malinin, A., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Bazo, J., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Becker, U., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Behlmann, M., Pensotti, S., Pereira, R., Pilo, F., Piluso, A., Pizzolotto, C., Plyaskin, V., Pohl, M., Poireau, V., Postaci, E., Putze, A., Alpat, B., Beischer, B., Quadrani, L., Qi, X. M., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozhkov, A., Rozza, D., Berdugo, J., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., Schuckardt, D., Schulz von Dratzig, A., Schwering, G., Scolieri, G., Bertucci, B., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, X. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Bigongiari, G., Sun, W., Sun, W. H., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Ting, Samuel C. C., Ting, S. M., Bindi, V., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vaurynovich, S., Vecchi, M., Bizzaglia, S., Velasco, M., Vialle, J. P., Wang, L. Q., Wang, Q. L., Wang, R. S., Wang, X., Wang, Z. X., Weng, Z. L., Whitman, K., Wienkenhöver, J., Bizzarri, M., Wu, H., Xia, X., Xie, M., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Xu, W., Yan, Q., Yang, J., Boella, G., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., de Boer, W., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Zuccon, P., Zurbach, C., AMS Collaboration, Bollweg, K., Alvino, A., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Burger, J., Cadoux, F., Cai, X. D., Capell, M., Caroff, S., Ambrosi, G., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cervelli, F., Chae, M. J., Chang, Y. H., Chen, A. I., Chen, H., Cheng, G. M., Andeen, K., Chen, H. S., Cheng, L., Chikanian, A., Chou, H. Y., Choumilov, E., Choutko, V., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Arruda, L., Consolandi, C., Contin, A., Corti, C., Coste, B., Crispoltoni, M., Cui, Z., Dai, M., Delgado, C., Della Torre, S., Demirköz, M. B., Attig, N., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Azzarello, P., Eline, A., Eppling, F. J., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Fisher, P., Bachlechner, A., Galaktionov, Y., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., and Gillard, W.

Subjects
Astrophysics::High Energy Astrophysical Phenomena, ddc:550, High Energy Physics::Experiment
Abstract

We present a measurement of the cosmic ray (e+ + e−) flux in the range 0.5 GeV to 1 TeV based on the analysis of 10.6 million (e+ + e−) events collected by AMS. The statistics and the resolution of AMS provide a precision measurement of the flux. The flux is smooth and reveals new and distinct information. Above 30.2 GeV, the flux can be described by a single power law with a spectral index γ=−3.170±0.008(stat+syst)±0.008(energy scale).

Published
2014

14. Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station

Author

Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xie, M., Xu, Weiwei, Yan, Qi, Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. J., Chang, Y. H., Cheng, G. M., Chen, H. S., Cheng, L., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Haas, D., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Levi, G., Li, H. L., Li, J. Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lolli, M., Lomtadze, T., Lu, M. J., Lu, S. Q., Lu, Y. S., Luebelsmeyer, K., Luo, J. Z., Lv, S. S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X. M., Qin, X., Qu, Z. Y., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Sun, W., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Vitale, V., Vitillo, S., Wang, L. Q., Wang, N. H., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Yang, J., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Zurbach, C., Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xie, M., Xu, Weiwei, Yan, Qi, Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. J., Chang, Y. H., Cheng, G. M., Chen, H. S., Cheng, L., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Haas, D., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Levi, G., Li, H. L., Li, J. Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lolli, M., Lomtadze, T., Lu, M. J., Lu, S. Q., Lu, Y. S., Luebelsmeyer, K., Luo, J. Z., Lv, S. S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X. M., Qin, X., Qu, Z. Y., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Sun, W., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Vitale, V., Vitillo, S., Wang, L. Q., Wang, N. H., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Yang, J., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., and Zurbach, C.

Abstract

A precise measurement of the proton flux in primary cosmic rays with rigidity (momentum/charge) from 1 GV to 1.8 TV is presented based on 300 million events. Knowledge of the rigidity dependence of the proton flux is important in understanding the origin, acceleration, and propagation of cosmic rays. We present the detailed variation with rigidity of the flux spectral index for the first time. The spectral index progressively hardens at high rigidities.

Published
2015

15. Precision Measurement of the Helium Flux in Primary Cosmic Rays of Rigidities 1.9 GV to 3 TV with the Alpha Magnetic Spectrometer on the International Space Station

Author

Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, H., Choumilov, Evgueni, Choutko, Vitali, Egorov, Alexander, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Tsai-hsiu, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, J. Q., Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, Wei, Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Willenbrock, Manfred, Xie, M., Xu, Weiwei, Yan, Q., Zhang, S. D., Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. J., Chang, Y. H., Chen, G. M., Chen, H. S., Cheng, L., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Formato, V., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Haas, D., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Korkmaz, M. A., Kossakowski, R., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Li, H. L., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Liu, Hu, Lolli, M., Lomtadze, T., Lu, M. J., Lu, S. Q., Lu, Y. S., Luebelsmeyer, K., Luo, F., Luo, J. Z., Lv, S. S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Nelson, T., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Putze, A., Quadrani, L., Qi, X. M., Qin, X., Qu, Z. Y., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Schael, S., Schmidt, S. M., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Song, J. W., Spada, F., Spinella, F., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Vitale, V., Vitillo, S., Wang, L. Q., Wang, N. H., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R. Q., Xu, N. S., Yang, J., Yang, M., Yang, Y., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, C., Zhang, J. H., Zhang, M. T., Zhang, S. W., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Becker, Ulrich J, Burger, Joseph D, Capell, Michael H, Chen, Andrew I, Eppling, Frederic J, Fisher, Peter H, Marks Ting, Susan Carol, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, H., Choumilov, Evgueni, Choutko, Vitali, Egorov, Alexander, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Tsai-hsiu, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, J. Q., Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, Wei, Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Willenbrock, Manfred, Xie, M., Xu, Weiwei, Yan, Q., Zhang, S. D., Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. J., Chang, Y. H., Chen, G. M., Chen, H. S., Cheng, L., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Formato, V., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Haas, D., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Korkmaz, M. A., Kossakowski, R., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Li, H. L., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Liu, Hu, Lolli, M., Lomtadze, T., Lu, M. J., Lu, S. Q., Lu, Y. S., Luebelsmeyer, K., Luo, F., Luo, J. Z., Lv, S. S., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Nelson, T., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Putze, A., Quadrani, L., Qi, X. M., Qin, X., Qu, Z. Y., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Schael, S., Schmidt, S. M., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Song, J. W., Spada, F., Spinella, F., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Vitale, V., Vitillo, S., Wang, L. Q., Wang, N. H., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R. Q., Xu, N. S., Yang, J., Yang, M., Yang, Y., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, C., Zhang, J. H., Zhang, M. T., Zhang, S. W., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Becker, Ulrich J, Burger, Joseph D, Capell, Michael H, Chen, Andrew I, Eppling, Frederic J, Fisher, Peter H, and Marks Ting, Susan Carol

Abstract

Knowledge of the precise rigidity dependence of the helium flux is important in understanding the origin, acceleration, and propagation of cosmic rays. A precise measurement of the helium flux in primary cosmic rays with rigidity (momentum/charge) from 1.9 GV to 3 TV based on 50 million events is presented and compared to the proton flux. The detailed variation with rigidity of the helium flux spectral index is presented for the first time. The spectral index progressively hardens at rigidities larger than 100 GV. The rigidity dependence of the helium flux spectral index is similar to that of the proton spectral index though the magnitudes are different. Remarkably, the spectral index of the proton to helium flux ratio increases with rigidity up to 45 GV and then becomes constant; the flux ratio above 45 GV is well described by a single power law.

Published
2015

16. Precision Measurement of the (e[superscript +] + e[superscript −) Flux in Primary Cosmic Rays from 0.5 GeV to 1 TeV with the Alpha Magnetic Spectrometer on the International Space Station

Author

Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, W., Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xie, M., Xu, Weiwei, Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cervelli, F., Chae, M. J., Chang, Y. H., Cheng, G. M., Chen, H. S., Cheng, L., Chikanian, A., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Coste, B., Crispoltoni, M., Cui, Z., Dai, M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., Kunz, S., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Li, H. L., Li, J. Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lomtadze, T., Lu, M. J., Lu, Y. S., Luebelsmeyer, K., Luo, F., Luo, J. Z., Lv, S. S., Majka, R., Malinin, A., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X. M., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., Schuckardt, D., Schulz von Dratzig, A., Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Wang, L. Q., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Xia, X., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Yan, Q., Yang, J., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., Zurbach, C., Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, Hai, Choumilov, Evgueni, Choutko, Vitali, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Timothy Hwa-wei, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, W., Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Xie, M., Xu, Weiwei, Zuccon, Paolo, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Beischer, B., Berdugo, J., Bertucci, B., Bigongiari, G., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. J., Bourquin, M., Cadoux, F., Caroff, S., Casaus, J., Cascioli, V., Castellini, G., Cernuda, I., Cervelli, F., Chae, M. J., Chang, Y. H., Cheng, G. M., Chen, H. S., Cheng, L., Chikanian, A., Chou, H. Y., Chung, C. H., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Coste, B., Crispoltoni, M., Cui, Z., Dai, M., Delgado, C., Della Torre, S., Demirköz, M. B., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Du, W. J., Duranti, M., D’Urso, D., Eronen, T., Fan, Y. Y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Gillard, W., Giovacchini, F., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. H., Habiby, M., Haino, S., Han, K. C., He, Z. H., Hoffman, J., Huang, Z. C., Huh, C., Incagli, M., Ionica, M., Jang, W. Y., Jinchi, H., Kanishev, K., Kim, G. N., Kim, K. S., Kirn, Th., Kossakowski, R., Kunz, S., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lee, H. T., Lee, S. C., Leluc, C., Li, H. L., Li, J. Q., Li, T. X., Li, W., Li, Y., Li, Z. H., Li, Z. Y., Lim, S., Lin, C. H., Lipari, P., Lippert, T., Liu, D., Liu, H., Lomtadze, T., Lu, M. J., Lu, Y. S., Luebelsmeyer, K., Luo, F., Luo, J. Z., Lv, S. S., Majka, R., Malinin, A., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. C., Morescalchi, L., Mott, P., Müller, M., Ni, J. Q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Pilo, F., Piluso, A., Pizzolotto, C., Pohl, M., Poireau, V., Postaci, E., Putze, A., Quadrani, L., Qi, X. M., Räihä, T., Rancoita, P. G., Rapin, D., Ricol, J. S., Rodríguez, I., Rosier-Lees, S., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Sbarra, C., Schael, S., Schmidt, S. M., Schuckardt, D., Schulz von Dratzig, A., Schwering, G., Scolieri, G., Seo, E. S., Shan, B. S., Shan, Y. H., Shi, J. Y., Shi, Y. M., Siedenburg, T., Son, D., Spada, F., Spinella, F., Tacconi, M., Tang, C. P., Tang, X. W., Tang, Z. C., Tao, L., Tescaro, D., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vecchi, M., Velasco, M., Vialle, J. P., Wang, L. Q., Wang, Q. L., Wang, R. S., Wang, Z. X., Whitman, K., Wienkenhöver, J., Wu, H., Xia, X., Xie, S., Xiong, R. Q., Xin, G. M., Xu, N. S., Yan, Q., Yang, J., Yang, M., Ye, Q. H., Yi, H., Yu, Y. J., Yu, Z. Q., Zeissler, S., Zhang, J. H., Zhang, M. T., Zhang, X. B., Zhang, Z., Zheng, Z. M., Zhuang, H. L., Zhukov, V., Zichichi, A., Zimmermann, N., and Zurbach, C.

Abstract

We present a measurement of the cosmic ray (e[superscript +] + e[superscript -]) flux in the range 0.5 GeV to 1 TeV based on the analysis of 10.6 million (e[superscript +] + e[superscript -]) events collected by AMS. The statistics and the resolution of AMS provide a precision measurement of the flux. The flux is smooth and reveals new and distinct information. Above 30.2 GeV, the flux can be described by a single power law with a spectral index γ = -3.170 ± 0.008(stat + syst) ± 0.008(energy scale).

Published
2014

17. Identifying the errors in monitoring glacier changes by multi-sources data using remote sensing and gis techniques in mt. Naimona'nyi region in the western himalayas on the tibetan plateau in China

Author

Ye, Q. H., Hamilton, G., Mayewski, P. A., Stein, A., Chen, Jun, Jiang, Jie, van Genderen, J., Department of Earth Observation Science, UT-I-ITC-ACQUAL, and Faculty of Geo-Information Science and Earth Observation

Subjects
Remote Sensing, Himalayas, Mt. Naimona'Nyi, Mt. Geladandong, Tibetan Plateau, The hybrid grid unit, Glacier variation, Geographic information system (GIS)
Abstract

The paper compares the results of two alternative methods for studying glacier variations in Mt. Naimona'Nyi in the western Himalayas on Tibet. This paper describes a grid method for studying multi-temporal glacier variations from space. By combining glacier spatial data from various satellite images or maps at sequential times, the grid method allows us to detect both dynamic variation and random noise in glacier distribution among the sequential data sets due to different data sources. Our results show that random noise, equal to 5.5% of the total glacier area in the Mt. Naimona'Nyi region, as taken from individual classification results by bands algorithms, was much larger than that of the measurement uncertainty calculated by sensor resolution and co-registration error. Glaciers in the region both retreated and advanced during the last several decades. Retreat dominates, however, and accelerates. Most of the glacier retreat area occurs at the termini of glaciers in the southeastern slopes of the two regions, whereas most of the glacier advance area occurs at the termini of glaciers in the northwestern slopes. The glacier recessions in the Mt. Naimona'Nyi of the Himalayan regions are dramatic compared with Mt. Geladandong region in the central Tibetan Plateau.

Published
2008

24. Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM+ AFP+ hepatocellular carcinoma.

Author

Zhao, X, Parpart, S, Takai, A, Roessler, S, Budhu, A, Yu, Z, Blank, M, Zhang, Y E, Jia, H-L, Ye, Q-H, Qin, L-X, Tang, Z-Y, Thorgeirsson, S S, and Wang, X W

Subjects
LIVER cancer, ONCOGENES, LIVER transplantation, SURGICAL excision, LIVER cancer patients, EPITHELIAL cells, CELL adhesion, GENETICS, PROGNOSIS
Abstract

Identification of key drivers and new therapeutic targets is important given the poor prognosis for hepatocellular carcinoma (HCC) patients, particularly those ineligible for surgical resection or liver transplant. However, the approach to identify such driver genes is facing significant challenges due to the genomically heterogenous nature of HCC. Here we tested whether the integrative genomic profiling of a well-defined HCC subset that is classified by an extreme EpCAM+ AFP+ gene expression signature and associated with poor prognosis, all attributes of a stem cell-like phenotype, could uncover survival-related driver genes in HCC. Following transcriptomic analysis of the well-defined HCC cases, a Gene Set Enrichment Analysis coupled with genomic copy number alteration assessment revealed that YY1-associated protein 1 (YY1AP1) is a critical oncoprotein specifically activated in EpCAM+ AFP+ HCC. YY1AP1 silencing eliminates oncogene addiction by altering the chromatin landscape and triggering massive apoptosis in vitro and tumor suppression in vivo. YY1AP1 expression promotes HCC proliferation and is required for the maintenance of stem cell features. We revealed that YY1AP1 cooperates with YY1 to alter the chromatin landscape and activate transcription of stemness regulators. Thus YY1AP1 may serve as a key molecular target for EpCAM+ AFP+ HCC subtype. Our results demonstrate the feasibility and power of a new strategy by utilizing well-defined patient samples and integrative genomics to uncover critical pathways linked to HCC subtypes with prognostic impact. [ABSTRACT FROM AUTHOR]

Published
2015
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32. Precision Measurement of the Helium Flux in Primary Cosmic Rays of Rigidities 1.9 GV to 3 TV with the Alpha Magnetic Spectrometer on the International Space Station

Author

N. Nikonov, Corrado Gargiulo, A. Egorov, I. Cernuda, Carlos Díaz, W. De Boer, Corinne Goy, Wei Sun, Haifeng Li, P. Vialle, E. Fiandrini, H. S. Chen, Zhiqi Huang, Xiaoqun Wang, I. Gebauer, C. Türkoğlu, Arturo Alejandro Menchaca-Rocha, S. Krafczyk, L. Tao, S. Xie, J. Q. Ni, Fabrizio Giulio Luca Pilo, F. Spinella, S. S. Lv, Maria Ionica, S. Chen, Markus Battarbee, J. Gong, J. Sandweiss, H. Y. Chou, R. D. Majka, S. Wang, Z. Q. Yu, O. Kounina, Paolo Zuccon, Samuel C.C. Ting, H. Yi, H. Wu, Z. Cui, W. Tang, H. Shan, M. Qi, Matthias Heil, E. Finch, J. H. Zhang, S. Zhang, W. Creus, G. Laurenti, T. J. N. Nelson, E. Valente, M. Paniccia, A. Von Dratzig, Davide Rozza, K. Andeen, L. Farnesini, I. Rodríguez, Chuanguo Zhang, Z. L. Weng, D. Rapin, V. Plyaskin, A. Lebedev, A. Papi, Dong-Chul Son, P. Tang, J. W. Song, J. Wienkenhöver, Andrea Contin, Hengchang Liu, S. Lim, H. Sun, Philipp Azzarello, N. Masi, F. Luo, L. Barrin, Z. Qu, M. Willenbrock, J. J. Torsti, S. Pensotti, G. La Vacca, Mauro Tacconi, Roald Z. Sagdeev, Yang Yang, G. Schwering, Antonino Zichichi, G. Coignet, David Maurin, Xin Wu, J. Eppling, S. Della Torre, M. Crispoltoni, S. Rosier-Lees, J. Casaus, L. Qu, Chung-Cherng Lin, Teimuraz Lomtadze, M. B. Demirköz, C. Han, Henning Gast, M. Aguilar, Matteo Boschini, Chau-Hwang Lee, J. Berdugo, A. Fiasson, F. Dimiccoli, Wei Li, Laurent Derome, A. Bartoloni, X. Xia, C. Pizzolotto, R. J. García-López, Y. Fan, E. Choumilov, J. C. Marin, V. Poireau, Xubo Qin, P. Mott, Yun Shi, R. Kossakowski, Franck Cadoux, P. Nunes, A. Rozhkov, F. Spada, Lin Cheng, N. Picot-Clemente, F. Palmonari, M. Bourquin, C. Ting, L. Di Masso, M. Bizzarri, M. Duranti, E. Pedreschi, L. Basara, U. Becker, C. H. Chung, Xinxin Li, Y. J. Yu, S. Zeissler, Yu. Galaktionov, D. Aisa, I. Guerri, G. Boella, Varlen Grabski, M. Vecchi, Massimo Gervasi, Dong Liu, Z. Luo, Thomas Lippert, S. Q. Lu, Mayda Velasco, Valery Zhukov, M. T. Zhang, S. Vitillo, Z. M. Zheng, Fernando Barão, M. Pauluzzi, Bruce Rafael Mellado Garcia, Z. H. He, A. I. Chen, V. Vitale, F. Nozzoli, H. Jinchi, M. Behlmann, T. Siedenburg, A. Piluso, D. Cerreta, A. Ghelfi, M. Capell, Claudio Corti, Ningsheng Xu, G. Ambrosi, S. Caroff, J. Hoffman, T. Eronen, R. Clavero, D. Grandi, W. Xu, Naihua Wang, F. Cervelli, A. Obermeier, E. Gil, P. Lipari, T. Räihä, P. Goglov, I. Lazzizzera, M. Pohl, B. Bertucci, M. Xie, H. Ye, C. Mañá, Veronica Bindi, G. Scolieri, Nicola Tomassetti, Shihao Zhang, Hsiang Szu Chang, Behcet Alpat, Luísa Arruda, Antje Putze, T. Kirn, D. Haas, V. Vagelli, Shinhong Kim, C. Mo, Pier-Giorgio Rancoita, Q. Meng, Sadakazu Haino, H. L. Zhuang, A. Barrau, S. J. Schmidt, Q. L. Wang, C. Delgado, T. Urban, V. Choutko, A. Korkmaz, S. Seo, M. J. Chae, C. Guandalini, R. Pereira, M. Chen, K. Bollweg, Miaoran Lu, Zheng Wang, M. Habiby, B. Coste, M. Graziani, V. Formato, Horngming Hsieh, M. Incagli, K. Whitman, Ju Li, Roberto Battiston, B. Borgia, J. Yang, H. Guo, M. Müller, Changgi Huh, Zhijun Zhang, P. Saouter, S. Di Falco, Peter H. Fisher, Tim Martin, F. Giovacchini, Luca Morescalchi, Q. Xiong, K. Luebelsmeyer, Zhixiang Tang, M. Orcinha, A. Alvino, C. Vannini, S. Shan, P. von Doetinchem, N. Kim, X. D. Cai, F. Donnini, N. Attig, Hyun Lee, Andrei Kounine, Q. Yan, N. Zimmermann, S. Borsini, G. Castellini, J. Feng, G. Martinez, C. Palomares, C. Clark, S. Schael, C. Consolandi, Elisa Laudi, J. D. Burger, S. S. Vaurynovich, D. Tescaro, Yongyao Li, Mingming Yang, A. Oliva, D. D'Urso, C. Leluc, G. Gallucci, Yaomin Dai, B. Beischer, V. Bonnivard, K. Kanishev, S. Bizzaglia, Y. Jang, A. Bachlechner, X. B. Zhang, J. Bazo, V. Koutsenko, Eino Valtonen, Z. H. Li, Qiang Li, S. Ricol, M. Lolli, A. Eline, Massachusetts Institute of Technology. Department of Physics, Massachusetts Institute of Technology. Laboratory for Nuclear Science, Becker, Ulrich J., Behlmann, Matthew Daniel, Burger, Joseph D., Cai, Xudong, Capell, Michael H., Chen, Andrew I., Chen, H., Choumilov, Evgueni, Choutko, Vitali, Egorov, Alexander, Eline, Alexandre, Eppling, Frederic J., Fisher, Peter H., Galaktionov, Y., Goglov, Pavel, Heil, Melanie, Hsieh, Tsai-hsiu, Kounina, Olga, Kounine, Andrei, Koutsenko, Vladimir, Krafczyk, Matthew Scott, Lebedev, Alexei, Li, J. Q., Li, Q., Plyaskin, Vasily, Rozhkov, Andrey B., Shi, X. Y., Sun, Wei, Sun, W. H., Ting, Samuel, Ting, Susan Marks, Vaurynovich, Siarhei S., Wang, Xiaozhen, Weng, Zhili, Willenbrock, Manfred, Xie, M., Xu, Weiwei, Yan, Q., Zhang, S. D., Zuccon, Paolo, Azzarello, Philipp, Bourquin, Maurice, Cadoux, Franck, Cortina Gil, Eduardo, Haas, Daniel, Habiby Alaoui, Marion, Leluc, Catherine, Li, Yang, Paniccia, Mercedes, Pohl, Martin, Rapin, Divic Jean, Saouter, Pierre, Vitillo, Stefania, Wu, Xin, Aguilar, M, Aisa, D, Alpat, B, Alvino, A, Ambrosi, G, Andeen, K, Arruda, L, Attig, N, Azzarello, P, Bachlechner, A, Barao, F, Barrau, A, Barrin, L, Bartoloni, A, Basara, L, Battarbee, M, Battiston, R, Bazo, J, Becker, U, Behlmann, M, Beischer, B, Berdugo, J, Bertucci, B, Bindi, V, Bizzaglia, S, Bizzarri, M, Boella, G, de Boer, W, Bollweg, K, Bonnivard, V, Borgia, B, Borsini, S, Boschini, M, Bourquin, M, Burger, J, Cadoux, F, Cai, X, Capell, M, Caroff, S, Casaus, J, Castellini, G, Cernuda, I, Cerreta, D, Cervelli, F, Chae, M, Chang, Y, Chen, A, Chen, G, Chen, H, Cheng, L, Chou, H, Choumilov, E, Choutko, V, Chung, C, Clark, C, Clavero, R, Coignet, G, Consolandi, C, Contin, A, Corti, C, Gil, E, Coste, B, Creus, W, Crispoltoni, M, Cui, Z, Dai, Y, Delgado, C, Della Torre, S, Demirköz, M, Derome, L, Di Falco, S, Di Masso, L, Dimiccoli, F, Díaz, C, von Doetinchem, P, Donnini, F, Duranti, M, D’Urso, D, Egorov, A, Eline, A, Eppling, F, Eronen, T, Fan, Y, Farnesini, L, Feng, J, Fiandrini, E, Fiasson, A, Finch, E, Fisher, P, Formato, V, Galaktionov, Y, Gallucci, G, García, B, García López, R, Gargiulo, C, Gast, H, Gebauer, I, Gervasi, M, Ghelfi, A, Giovacchini, F, Goglov, P, Gong, J, Goy, C, Grabski, V, Grandi, D, Graziani, M, Guandalini, C, Guerri, I, Guo, K, Haas, D, Habiby, M, Haino, S, Han, K, He, Z, Heil, M, Hoffman, J, Hsieh, T, Huang, Z, Huh, C, Incagli, M, Ionica, M, Jang, W, Jinchi, H, Kanishev, K, Kim, G, Kim, K, Kirn, T, Korkmaz, M, Kossakowski, R, Kounina, O, Kounine, A, Koutsenko, V, Krafczyk, M, LA VACCA, G, Laudi, E, Laurenti, G, Lazzizzera, I, Lebedev, A, Lee, H, Lee, S, Leluc, C, Li, H, Li, J, Li, Q, Li, T, Li, W, Li, Y, Li, Z, Lim, S, Lin, C, Lipari, P, Lippert, T, Liu, D, Liu, H, Lolli, M, Lomtadze, T, Lu, M, Lu, S, Lu, Y, Luebelsmeyer, K, Luo, F, Luo, J, Lv, S, Majka, R, Mañá, C, Marín, J, Martin, T, Martínez, G, Masi, N, Maurin, D, Menchaca Rocha, A, Meng, Q, Mo, D, Morescalchi, L, Mott, P, Müller, M, Nelson, T, Ni, J, Nikonov, N, Nozzoli, F, Nunes, P, Obermeier, A, Oliva, A, Orcinha, M, Palmonari, F, Palomares, C, Paniccia, M, Papi, A, Pauluzzi, M, Pedreschi, E, Pensotti, S, Pereira, R, Picot Clemente, N, Pilo, F, Piluso, A, Pizzolotto, C, Plyaskin, V, Pohl, M, Poireau, V, Putze, A, Quadrani, L, Qi, X, Qin, X, Qu, Z, Räihä, T, Rancoita, P, Rapin, D, Ricol, J, Rodríguez, I, Rosier Lees, S, Rozhkov, A, Rozza, D, Sagdeev, R, Sandweiss, J, Saouter, P, Schael, S, Schmidt, S, von Dratzig, A, Schwering, G, Scolieri, G, Seo, E, Shan, B, Shan, Y, Shi, J, Shi, X, Shi, Y, Siedenburg, T, Son, D, Song, J, Spada, F, Spinella, F, Sun, W, Tacconi, M, Tang, C, Tang, X, Tang, Z, Tao, L, Tescaro, D, Ting, S, Tomassetti, N, Torsti, J, Türkoğlu, C, Urban, T, Vagelli, V, Valente, E, Vannini, C, Valtonen, E, Vaurynovich, S, Vecchi, M, Velasco, M, Vialle, J, Vitale, V, Vitillo, S, Wang, L, Wang, N, Wang, Q, Wang, R, Wang, X, Wang, Z, Weng, Z, Whitman, K, Wienkenhöver, J, Willenbrock, M, Wu, H, Wu, X, Xia, X, Xie, M, Xie, S, Xiong, R, Xu, N, Xu, W, Yan, Q, Yang, J, Yang, M, Yang, Y, Ye, Q, Yi, H, Yu, Y, Yu, Z, Zeissler, S, Zhang, C, Zhang, J, Zhang, M, Zhang, S, Zhang, X, Zhang, Z, Zheng, Z, Zhuang, H, Zhukov, V, Zichichi, A, Zimmermann, N, Zuccon, P, Aguilar, M., Aisa, D., Alpat, B., Alvino, A., Ambrosi, G., Andeen, K., Arruda, L., Attig, N., Azzarello, P., Bachlechner, A., Barao, F., Barrau, A., Barrin, L., Bartoloni, A., Basara, L., Battarbee, M., Battiston, R., Bazo, J., Becker, U., Behlmann, M., Beischer, B., Berdugo, J., Bertucci, B., Bindi, V., Bizzaglia, S., Bizzarri, M., Boella, G., de Boer, W., Bollweg, K., Bonnivard, V., Borgia, B., Borsini, S., Boschini, M. j., Bourquin, M., Burger, J., Cadoux, F., Cai, X. d., Capell, M., Caroff, S., Casaus, J., Castellini, G., Cernuda, I., Cerreta, D., Cervelli, F., Chae, M. j., Chang, Y. h., Chen, A. i., Chen, G. m., Chen, H. s., Cheng, L., Chou, H. y., Choumilov, E., Choutko, V., Chung, C. h., Clark, C., Clavero, R., Coignet, G., Consolandi, C., Contin, A., Corti, C., Gil, E. Cortina, Coste, B., Creus, W., Crispoltoni, M., Cui, Z., Dai, Y. m., Delgado, C., Della Torre, S., Demirköz, M. b., Derome, L., Di Falco, S., Di Masso, L., Dimiccoli, F., Díaz, C., von Doetinchem, P., Donnini, F., Duranti, M., D’Urso, D., Egorov, A., Eline, A., Eppling, F. j., Eronen, T., Fan, Y. y., Farnesini, L., Feng, J., Fiandrini, E., Fiasson, A., Finch, E., Fisher, P., Formato, V., Gallucci, G., García, B., García-López, R., Gargiulo, C., Gast, H., Gebauer, I., Gervasi, M., Ghelfi, A., Giovacchini, F., Goglov, P., Gong, J., Goy, C., Grabski, V., Grandi, D., Graziani, M., Guandalini, C., Guerri, I., Guo, K. h., Haas, D., Habiby, M., Haino, S., Han, K. c., He, Z. h., Heil, M., Hoffman, J., Hsieh, T. h., Huang, Z. c., Huh, C., Incagli, M., Ionica, M., Jang, W. y., Jinchi, H., Kanishev, K., Kim, G. n., Kim, K. s., Kirn, Th., Korkmaz, M. a., Kossakowski, R., Kounina, O., Kounine, A., Koutsenko, V., Krafczyk, M. s., La Vacca, G., Laudi, E., Laurenti, G., Lazzizzera, I., Lebedev, A., Lee, H. t., Lee, S. c., Leluc, C., Li, H. l., Li, J. q., Li, T. x., Li, W., Li, Y., Li, Z. h., Li, Z. y., Lim, S., Lin, C. h., Lipari, P., Lippert, T., Liu, D., Liu, H., Liu, Hu, Lolli, M., Lomtadze, T., Lu, M. j., Lu, S. q., Lu, Y. s., Luebelsmeyer, K., Luo, F., Luo, J. z., Lv, S. s., Majka, R., Mañá, C., Marín, J., Martin, T., Martínez, G., Masi, N., Maurin, D., Menchaca-Rocha, A., Meng, Q., Mo, D. c., Morescalchi, L., Mott, P., Müller, M., Nelson, T., Ni, J. q., Nikonov, N., Nozzoli, F., Nunes, P., Obermeier, A., Oliva, A., Orcinha, M., Palmonari, F., Palomares, C., Paniccia, M., Papi, A., Pauluzzi, M., Pedreschi, E., Pensotti, S., Pereira, R., Picot-Clemente, N., Pilo, F., Piluso, A., Pizzolotto, C., Plyaskin, V., Pohl, M., Poireau, V., Putze, A., Quadrani, L., Qi, X. m., Qin, X., Qu, Z. y., Räihä, T., Rancoita, P. g., Rapin, D., Ricol, J. s., Rodríguez, I., Rosier-Lees, S., Rozhkov, A., Rozza, D., Sagdeev, R., Sandweiss, J., Saouter, P., Schael, S., Schmidt, S. m., von Dratzig, A. Schulz, Schwering, G., Scolieri, G., Seo, E. s., Shan, B. s., Shan, Y. h., Shi, J. y., Shi, X. y., Shi, Y. m., Siedenburg, T., Son, D., Song, J. w., Spada, F., Spinella, F., Sun, W., Sun, W. h., Tacconi, M., Tang, C. p., Tang, X. w., Tang, Z. c., Tao, L., Tescaro, D., Ting, Samuel C. C., Ting, S. m., Tomassetti, N., Torsti, J., Türkoğlu, C., Urban, T., Vagelli, V., Valente, E., Vannini, C., Valtonen, E., Vaurynovich, S., Vecchi, M., Velasco, M., Vialle, J. p., Vitale, V., Vitillo, S., Wang, L. q., Wang, N. h., Wang, Q. l., Wang, R. s., Wang, X., Wang, Z. x., Weng, Z. l., Whitman, K., Wienkenhöver, J., Willenbrock, M., Wu, H., Wu, X., Xia, X., Xie, S., Xiong, R. q., Xu, N. s., Xu, W., Yang, J., Yang, M., Yang, Y., Ye, Q. h., Yi, H., Yu, Y. j., Yu, Z. q., Zeissler, S., Zhang, C., Zhang, J. h., Zhang, M. t., Zhang, S. d., Zhang, S. w., Zhang, X. b., Zhang, Z., Zheng, Z. m., Zhuang, H. l., Zhukov, V., Zichichi, A., Zimmermann, N., Zuccon, P., UCL - SST/IRMP - Institut de recherche en mathématique et physique, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), and AMS Collaboration

Subjects
Astrophysics and Astronomy, Astrophysics::High Energy Astrophysical Phenomena, General Physics and Astronomy, chemistry.chemical_element, Cosmic ray, Astrophysics, ddc:500.2, Power law, Helium, Space missions, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], FIS/05 - ASTRONOMIA E ASTROFISICA, Physics and Astronomy (all), Rigidity (electromagnetism), International Space Station, Alpha Magnetic Spectrometer, ddc:550, AMS, Helium Flux, Primary Cosmic Rays, Cosmic rays, Physics, Spectral index, ta114, Cosmic Rays, Cosmic Helium, Spectral density, ASTROFÍSICA, Computational physics, FIS/01 - FISICA SPERIMENTALE, chemistry, Cosmic ray measurement, Cosmology, Rigidity, Space stations, Spectrometers
Abstract

Physical review letters 115(21), 211101 (2015). doi:10.1103/PhysRevLett.115.211101, Published by APS, College Park, Md.

Published
2015

34. [Analysis of the social support and related factors of the elderly in the elderly activity centers in Macao, Hong Kong and Guangzhou].

Author

Ye QH, Gu Q, and Leong QR

Subjects
Aged, China, Cities, Female, Hong Kong, Humans, Macau, Male, Middle Aged, Personal Satisfaction, Social Support
Abstract

Research participants were recruited at 16 elderly activity centers among three cities in Macao, Hong Kong and Guangzhou. A total of 324 people were surveyed, with women ≥ 55 years old and men ≥ 60 years old; There were 90, 100 and 134 in Macao, Hong Kong and Guangzhou respectively. The median ( P (25) , P (75)) score of the social support rating scale (SSRS) for the elderly was 30 (25, 38) for Macao, 24 (20, 29) for Hong Kong and 30 (26, 37) for Guangzhou respectively. The elderly in Macao and Guangzhou had a higher proportion of the SSRS in the middle and high groups (85.20%, 84.50%) when compared to the elderly in Hong Kong (62.10%) ( P< 0.05). The city, marital status, and personal well-being index are related to SSRS scores.

Published
2019
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35. [Analysis of relationship between personal wellbeing index and related factors in the elderly aged 55 or above, who visit the day care centers in Macao, Hong Kong and Guangzhou].

Author

Ye QH, Wen YZ, Liang QR, and Gu Q

Subjects
Aged, China, Cities, Female, Hong Kong, Humans, Macau, Male, Middle Aged, Socioeconomic Factors, Surveys and Questionnaires, Adult Day Care Centers statistics & numerical data, Personal Satisfaction
Abstract

Objective: To investigate the personal wellbeing index (PWI) among elderly aged 55 and above from the elderly day care centers in Macao, Hong Kong and Guangzhou, and associated factors. Methods: We used convenient sampling to select participants from 16 elderly day care centers in Macao, Hong Kong and Guangzhou. Inclusion criteria were: females aged 55 or above, males 60 or above, the participants who were conscious and clearly understood the questionnaire. Informed consent form was signed by the participants. A total of 324 elderly participated in the study: 90 from Macao, 100 from Hong Kong, and 134 from Guangzhou. Close-end questionnaire was used to collect demographic information and PWI inventory (Cantonese version) was used to assess the PWI scores. Comparison in the PWI scores difference was conducted. Multiple regression method was used to analyze factors associated with PWI. Results: The PWI was 7.3±1.9 (Macao: 7.7±1.9, Hong Kong: 7.2±1.7, Guangzhou: 7.0±1.9) ( F= 3.32, P= 0.037). The multiple regression analysis showed that comparing to those who did exercised 3 times or less, or single/devoiced/separated, or had no education, the elderly who did exercised 4 times or more per week or married/widowed, or received education in primary school or above had higher PWI scores. The beta values (95% CI ) were 0.82 (95 % CI: 0.31-1.34), 1.03 (95 % CI: 0.12-1.94), 0.51 (95 % CI: 0.04-0.99) respectively. Conclusion: The elderly participants aged 55 or above who went to elderly day care centers in three cities had higher PWI score generally. Marital status, participate in sufficient physical activity and advanced education level were significant related to PWI.

Published
2018
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36. Precision Measurement of the Helium Flux in Primary Cosmic Rays of Rigidities 1.9 GV to 3 TV with the Alpha Magnetic Spectrometer on the International Space Station.

Author

Aguilar M, Aisa D, Alpat B, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, Battarbee M, Battiston R, Bazo J, Becker U, Behlmann M, Beischer B, Berdugo J, Bertucci B, Bindi V, Bizzaglia S, Bizzarri M, Boella G, de Boer W, Bollweg K, Bonnivard V, Borgia B, Borsini S, Boschini MJ, Bourquin M, Burger J, Cadoux F, Cai XD, Capell M, Caroff S, Casaus J, Castellini G, Cernuda I, Cerreta D, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen GM, Chen H, Chen HS, Cheng L, Chou HY, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Consolandi C, Contin A, Corti C, Gil EC, Coste B, Creus W, Crispoltoni M, Cui Z, Dai YM, Delgado C, Della Torre S, Demirköz MB, Derome L, Di Falco S, Di Masso L, Dimiccoli F, Díaz C, von Doetinchem P, Donnini F, Duranti M, D'Urso D, Egorov A, Eline A, Eppling FJ, Eronen T, Fan YY, Farnesini L, Feng J, Fiandrini E, Fiasson A, Finch E, Fisher P, Formato V, Galaktionov Y, Gallucci G, García B, García-López R, Gargiulo C, Gast H, Gebauer I, Gervasi M, Ghelfi A, Giovacchini F, Goglov P, Gong J, Goy C, Grabski V, Grandi D, Graziani M, Guandalini C, Guerri I, Guo KH, Haas D, Habiby M, Haino S, Han KC, He ZH, Heil M, Hoffman J, Hsieh TH, Huang ZC, Huh C, Incagli M, Ionica M, Jang WY, Jinchi H, Kanishev K, Kim GN, Kim KS, Kirn T, Korkmaz MA, Kossakowski R, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, La Vacca G, Laudi E, Laurenti G, Lazzizzera I, Lebedev A, Lee HT, Lee SC, Leluc C, Li HL, Li JQ, Li JQ, Li Q, Li Q, Li TX, Li W, Li Y, Li ZH, Li ZY, Lim S, Lin CH, Lipari P, Lippert T, Liu D, Liu H, Liu H, Lolli M, Lomtadze T, Lu MJ, Lu SQ, Lu YS, Luebelsmeyer K, Luo F, Luo JZ, Lv SS, Majka R, Mañá C, Marín J, Martin T, Martínez G, Masi N, Maurin D, Menchaca-Rocha A, Meng Q, Mo DC, Morescalchi L, Mott P, Müller M, Nelson T, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oliva A, Orcinha M, Palmonari F, Palomares C, Paniccia M, Papi A, Pauluzzi M, Pedreschi E, Pensotti S, Pereira R, Picot-Clemente N, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pohl M, Poireau V, Putze A, Quadrani L, Qi XM, Qin X, Qu ZY, Räihä T, Rancoita PG, Rapin D, Ricol JS, Rodríguez I, Rosier-Lees S, Rozhkov A, Rozza D, Sagdeev R, Sandweiss J, Saouter P, Schael S, Schmidt SM, von Dratzig AS, Schwering G, Scolieri G, Seo ES, Shan BS, Shan YH, Shi JY, Shi XY, Shi YM, Siedenburg T, Son D, Song JW, Spada F, Spinella F, Sun W, Sun WH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tescaro D, Ting SC, Ting SM, Tomassetti N, Torsti J, Türkoğlu C, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vaurynovich S, Vecchi M, Velasco M, Vialle JP, Vitale V, Vitillo S, Wang LQ, Wang NH, Wang QL, Wang RS, Wang X, Wang ZX, Weng ZL, Whitman K, Wienkenhöver J, Willenbrock M, Wu H, Wu X, Xia X, Xie M, Xie S, Xiong RQ, Xu NS, Xu W, Yan Q, Yang J, Yang M, Yang Y, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang C, Zhang JH, Zhang MT, Zhang SD, Zhang SW, Zhang XB, Zhang Z, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zimmermann N, and Zuccon P

Abstract

Knowledge of the precise rigidity dependence of the helium flux is important in understanding the origin, acceleration, and propagation of cosmic rays. A precise measurement of the helium flux in primary cosmic rays with rigidity (momentum/charge) from 1.9 GV to 3 TV based on 50 million events is presented and compared to the proton flux. The detailed variation with rigidity of the helium flux spectral index is presented for the first time. The spectral index progressively hardens at rigidities larger than 100 GV. The rigidity dependence of the helium flux spectral index is similar to that of the proton spectral index though the magnitudes are different. Remarkably, the spectral index of the proton to helium flux ratio increases with rigidity up to 45 GV and then becomes constant; the flux ratio above 45 GV is well described by a single power law.

Published
2015
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37. Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station.

Author

Aguilar M, Aisa D, Alpat B, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, Battarbee M, Battiston R, Bazo J, Becker U, Behlmann M, Beischer B, Berdugo J, Bertucci B, Bigongiari G, Bindi V, Bizzaglia S, Bizzarri M, Boella G, de Boer W, Bollweg K, Bonnivard V, Borgia B, Borsini S, Boschini MJ, Bourquin M, Burger J, Cadoux F, Cai XD, Capell M, Caroff S, Casaus J, Cascioli V, Castellini G, Cernuda I, Cerreta D, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen H, Cheng GM, Chen HS, Cheng L, Chou HY, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Consolandi C, Contin A, Corti C, Cortina Gil E, Coste B, Creus W, Crispoltoni M, Cui Z, Dai YM, Delgado C, Della Torre S, Demirköz MB, Derome L, Di Falco S, Di Masso L, Dimiccoli F, Díaz C, von Doetinchem P, Donnini F, Du WJ, Duranti M, D'Urso D, Eline A, Eppling FJ, Eronen T, Fan YY, Farnesini L, Feng J, Fiandrini E, Fiasson A, Finch E, Fisher P, Galaktionov Y, Gallucci G, García B, García-López R, Gargiulo C, Gast H, Gebauer I, Gervasi M, Ghelfi A, Gillard W, Giovacchini F, Goglov P, Gong J, Goy C, Grabski V, Grandi D, Graziani M, Guandalini C, Guerri I, Guo KH, Haas D, Habiby M, Haino S, Han KC, He ZH, Heil M, Hoffman J, Hsieh TH, Huang ZC, Huh C, Incagli M, Ionica M, Jang WY, Jinchi H, Kanishev K, Kim GN, Kim KS, Kirn T, Kossakowski R, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, La Vacca G, Laudi E, Laurenti G, Lazzizzera I, Lebedev A, Lee HT, Lee SC, Leluc C, Levi G, Li HL, Li JQ, Li Q, Li Q, Li TX, Li W, Li Y, Li ZH, Li ZY, Lim S, Lin CH, Lipari P, Lippert T, Liu D, Liu H, Lolli M, Lomtadze T, Lu MJ, Lu SQ, Lu YS, Luebelsmeyer K, Luo JZ, Lv SS, Majka R, Mañá C, Marín J, Martin T, Martínez G, Masi N, Maurin D, Menchaca-Rocha A, Meng Q, Mo DC, Morescalchi L, Mott P, Müller M, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oliva A, Orcinha M, Palmonari F, Palomares C, Paniccia M, Papi A, Pauluzzi M, Pedreschi E, Pensotti S, Pereira R, Picot-Clemente N, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pohl M, Poireau V, Postaci E, Putze A, Quadrani L, Qi XM, Qin X, Qu ZY, Räihä T, Rancoita PG, Rapin D, Ricol JS, Rodríguez I, Rosier-Lees S, Rozhkov A, Rozza D, Sagdeev R, Sandweiss J, Saouter P, Sbarra C, Schael S, Schmidt SM, Schulz von Dratzig A, Schwering G, Scolieri G, Seo ES, Shan BS, Shan YH, Shi JY, Shi XY, Shi YM, Siedenburg T, Son D, Spada F, Spinella F, Sun W, Sun WH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tescaro D, Ting SC, Ting SM, Tomassetti N, Torsti J, Türkoğlu C, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vaurynovich S, Vecchi M, Velasco M, Vialle JP, Vitale V, Vitillo S, Wang LQ, Wang NH, Wang QL, Wang RS, Wang X, Wang ZX, Weng ZL, Whitman K, Wienkenhöver J, Wu H, Wu X, Xia X, Xie M, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JH, Zhang MT, Zhang XB, Zhang Z, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zimmermann N, Zuccon P, and Zurbach C

Abstract

A precise measurement of the proton flux in primary cosmic rays with rigidity (momentum/charge) from 1 GV to 1.8 TV is presented based on 300 million events. Knowledge of the rigidity dependence of the proton flux is important in understanding the origin, acceleration, and propagation of cosmic rays. We present the detailed variation with rigidity of the flux spectral index for the first time. The spectral index progressively hardens at high rigidities.

Published
2015
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38. Precision Measurement of the (e^{+}+e^{-}) Flux in Primary Cosmic Rays from 0.5 GeV to 1 TeV with the Alpha Magnetic Spectrometer on the International Space Station.

Author

Aguilar M, Aisa D, Alpat B, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, Battarbee M, Battiston R, Bazo J, Becker U, Behlmann M, Beischer B, Berdugo J, Bertucci B, Bigongiari G, Bindi V, Bizzaglia S, Bizzarri M, Boella G, de Boer W, Bollweg K, Bonnivard V, Borgia B, Borsini S, Boschini MJ, Bourquin M, Burger J, Cadoux F, Cai XD, Capell M, Caroff S, Casaus J, Cascioli V, Castellini G, Cernuda I, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen H, Cheng GM, Chen HS, Cheng L, Chikanian A, Chou HY, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Consolandi C, Contin A, Corti C, Coste B, Crispoltoni M, Cui Z, Dai M, Delgado C, Della Torre S, Demirköz MB, Derome L, Di Falco S, Di Masso L, Dimiccoli F, Díaz C, von Doetinchem P, Donnini F, Du WJ, Duranti M, D'Urso D, Eline A, Eppling FJ, Eronen T, Fan YY, Farnesini L, Feng J, Fiandrini E, Fiasson A, Finch E, Fisher P, Galaktionov Y, Gallucci G, García B, García-López R, Gargiulo C, Gast H, Gebauer I, Gervasi M, Ghelfi A, Gillard W, Giovacchini F, Goglov P, Gong J, Goy C, Grabski V, Grandi D, Graziani M, Guandalini C, Guerri I, Guo KH, Habiby M, Haino S, Han KC, He ZH, Heil M, Hoffman J, Hsieh TH, Huang ZC, Huh C, Incagli M, Ionica M, Jang WY, Jinchi H, Kanishev K, Kim GN, Kim KS, Kirn T, Kossakowski R, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Kunz S, La Vacca G, Laudi E, Laurenti G, Lazzizzera I, Lebedev A, Lee HT, Lee SC, Leluc C, Li HL, Li JQ, Li Q, Li Q, Li TX, Li W, Li Y, Li ZH, Li ZY, Lim S, Lin CH, Lipari P, Lippert T, Liu D, Liu H, Lomtadze T, Lu MJ, Lu YS, Luebelsmeyer K, Luo F, Luo JZ, Lv SS, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masi N, Maurin D, Menchaca-Rocha A, Meng Q, Mo DC, Morescalchi L, Mott P, Müller M, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oliva A, Orcinha M, Palmonari F, Palomares C, Paniccia M, Papi A, Pauluzzi M, Pedreschi E, Pensotti S, Pereira R, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pohl M, Poireau V, Postaci E, Putze A, Quadrani L, Qi XM, Räihä T, Rancoita PG, Rapin D, Ricol JS, Rodríguez I, Rosier-Lees S, Rozhkov A, Rozza D, Sagdeev R, Sandweiss J, Saouter P, Sbarra C, Schael S, Schmidt SM, Schuckardt D, Schulz von Dratzig A, Schwering G, Scolieri G, Seo ES, Shan BS, Shan YH, Shi JY, Shi XY, Shi YM, Siedenburg T, Son D, Spada F, Spinella F, Sun W, Sun WH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tescaro D, Ting SC, Ting SM, Tomassetti N, Torsti J, Türkoğlu C, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vaurynovich S, Vecchi M, Velasco M, Vialle JP, Wang LQ, Wang QL, Wang RS, Wang X, Wang ZX, Weng ZL, Whitman K, Wienkenhöver J, Wu H, Xia X, Xie M, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JH, Zhang MT, Zhang XB, Zhang Z, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zimmermann N, Zuccon P, and Zurbach C

Abstract

We present a measurement of the cosmic ray (e^{+}+e^{-}) flux in the range 0.5 GeV to 1 TeV based on the analysis of 10.6 million (e^{+}+e^{-}) events collected by AMS. The statistics and the resolution of AMS provide a precision measurement of the flux. The flux is smooth and reveals new and distinct information. Above 30.2 GeV, the flux can be described by a single power law with a spectral index γ=-3.170±0.008(stat+syst)±0.008(energy scale).

Published
2014
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39. High statistics measurement of the positron fraction in primary cosmic rays of 0.5-500 GeV with the alpha magnetic spectrometer on the international space station.

Author

Accardo L, Aguilar M, Aisa D, Alpat B, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, Battarbee M, Battiston R, Bazo J, Becker U, Behlmann M, Beischer B, Berdugo J, Bertucci B, Bigongiari G, Bindi V, Bizzaglia S, Bizzarri M, Boella G, de Boer W, Bollweg K, Bonnivard V, Borgia B, Borsini S, Boschini MJ, Bourquin M, Burger J, Cadoux F, Cai XD, Capell M, Caroff S, Carosi G, Casaus J, Cascioli V, Castellini G, Cernuda I, Cerreta D, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen H, Cheng GM, Chen HS, Cheng L, Chikanian A, Chou HY, Choumilov E, Choutko V, Chung CH, Cindolo F, Clark C, Clavero R, Coignet G, Consolandi C, Contin A, Corti C, Coste B, Cui Z, Dai M, Delgado C, Della Torre S, Demirköz MB, Derome L, Di Falco S, Di Masso L, Dimiccoli F, Díaz C, von Doetinchem P, Du WJ, Duranti M, D'Urso D, Eline A, Eppling FJ, Eronen T, Fan YY, Farnesini L, Feng J, Fiandrini E, Fiasson A, Finch E, Fisher P, Galaktionov Y, Gallucci G, García B, García-López R, Gast H, Gebauer I, Gervasi M, Ghelfi A, Gillard W, Giovacchini F, Goglov P, Gong J, Goy C, Grabski V, Grandi D, Graziani M, Guandalini C, Guerri I, Guo KH, Haas D, Habiby M, Haino S, Han KC, He ZH, Heil M, Henning R, Hoffman J, Hsieh TH, Huang ZC, Huh C, Incagli M, Ionica M, Jang WY, Jinchi H, Kanishev K, Kim GN, Kim KS, Kirn T, Kossakowski R, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Kunz S, La Vacca G, Laudi E, Laurenti G, Lazzizzera I, Lebedev A, Lee HT, Lee SC, Leluc C, Levi G, Li HL, Li JQ, Li Q, Li Q, Li TX, Li W, Li Y, Li ZH, Li ZY, Lim S, Lin CH, Lipari P, Lippert T, Liu D, Liu H, Lolli M, Lomtadze T, Lu MJ, Lu YS, Luebelsmeyer K, Luo F, Luo JZ, Lv SS, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masi N, Massera F, Maurin D, Menchaca-Rocha A, Meng Q, Mo DC, Monreal B, Morescalchi L, Mott P, Müller M, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oliva A, Orcinha M, Palmonari F, Palomares C, Paniccia M, Papi A, Pauluzzi M, Pedreschi E, Pensotti S, Pereira R, Pilastrini R, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pohl M, Poireau V, Postaci E, Putze A, Quadrani L, Qi XM, Rancoita PG, Rapin D, Ricol JS, Rodríguez I, Rosier-Lees S, Rossi L, Rozhkov A, Rozza D, Rybka G, Sagdeev R, Sandweiss J, Saouter P, Sbarra C, Schael S, Schmidt SM, Schuckardt D, Schulz von Dratzig A, Schwering G, Scolieri G, Seo ES, Shan BS, Shan YH, Shi JY, Shi XY, Shi YM, Siedenburg T, Son D, Spada F, Spinella F, Sun W, Sun WH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tescaro D, Ting SC, Ting SM, Tomassetti N, Torsti J, Türkoğlu C, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vaurynovich S, Vecchi M, Velasco M, Vialle JP, Vitale V, Volpini G, Wang LQ, Wang QL, Wang RS, Wang X, Wang ZX, Weng ZL, Whitman K, Wienkenhöver J, Wu H, Wu KY, Xia X, Xie M, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JH, Zhang MT, Zhang XB, Zhang Z, Zheng ZM, Zhou F, Zhuang HL, Zhukov V, Zichichi A, Zimmermann N, Zuccon P, and Zurbach C

Abstract

A precision measurement by AMS of the positron fraction in primary cosmic rays in the energy range from 0.5 to 500 GeV based on 10.9 million positron and electron events is presented. This measurement extends the energy range of our previous observation and increases its precision. The new results show, for the first time, that above ∼200  GeV the positron fraction no longer exhibits an increase with energy.

Published
2014
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40. Electron and positron fluxes in primary cosmic rays measured with the alpha magnetic spectrometer on the international space station.

Author

Aguilar M, Aisa D, Alvino A, Ambrosi G, Andeen K, Arruda L, Attig N, Azzarello P, Bachlechner A, Barao F, Barrau A, Barrin L, Bartoloni A, Basara L, Battarbee M, Battiston R, Bazo J, Becker U, Behlmann M, Beischer B, Berdugo J, Bertucci B, Bigongiari G, Bindi V, Bizzaglia S, Bizzarri M, Boella G, de Boer W, Bollweg K, Bonnivard V, Borgia B, Borsini S, Boschini MJ, Bourquin M, Burger J, Cadoux F, Cai XD, Capell M, Caroff S, Casaus J, Cascioli V, Castellini G, Cernuda I, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen H, Cheng GM, Chen HS, Cheng L, Chikanian A, Chou HY, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Consolandi C, Contin A, Corti C, Coste B, Cui Z, Dai M, Delgado C, Della Torre S, Demirköz MB, Derome L, Di Falco S, Di Masso L, Dimiccoli F, Díaz C, von Doetinchem P, Du WJ, Duranti M, D'Urso D, Eline A, Eppling FJ, Eronen T, Fan YY, Farnesini L, Feng J, Fiandrini E, Fiasson A, Finch E, Fisher P, Galaktionov Y, Gallucci G, García B, García-López R, Gast H, Gebauer I, Gervasi M, Ghelfi A, Gillard W, Giovacchini F, Goglov P, Gong J, Goy C, Grabski V, Grandi D, Graziani M, Guandalini C, Guerri I, Guo KH, Habiby M, Haino S, Han KC, He ZH, Heil M, Hoffman J, Hsieh TH, Huang ZC, Huh C, Incagli M, Ionica M, Jang WY, Jinchi H, Kanishev K, Kim GN, Kim KS, Kirn T, Kossakowski R, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Kunz S, La Vacca G, Laudi E, Laurenti G, Lazzizzera I, Lebedev A, Lee HT, Lee SC, Leluc C, Li HL, Li JQ, Li Q, Li Q, Li TX, Li W, Li Y, Li ZH, Li ZY, Lim S, Lin CH, Lipari P, Lippert T, Liu D, Liu H, Lomtadze T, Lu MJ, Lu YS, Luebelsmeyer K, Luo F, Luo JZ, Lv SS, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masi N, Maurin D, Menchaca-Rocha A, Meng Q, Mo DC, Morescalchi L, Mott P, Müller M, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oliva A, Orcinha M, Palmonari F, Palomares C, Paniccia M, Papi A, Pedreschi E, Pensotti S, Pereira R, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pohl M, Poireau V, Postaci E, Putze A, Quadrani L, Qi XM, Rancoita PG, Rapin D, Ricol JS, Rodríguez I, Rosier-Lees S, Rozhkov A, Rozza D, Sagdeev R, Sandweiss J, Saouter P, Sbarra C, Schael S, Schmidt SM, Schuckardt D, Schulz von Dratzig A, Schwering G, Scolieri G, Seo ES, Shan BS, Shan YH, Shi JY, Shi XY, Shi YM, Siedenburg T, Son D, Spada F, Spinella F, Sun W, Sun WH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tescaro D, Ting SC, Ting SM, Tomassetti N, Torsti J, Türkoğlu C, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vaurynovich S, Vecchi M, Velasco M, Vialle JP, Wang LQ, Wang QL, Wang RS, Wang X, Wang ZX, Weng ZL, Whitman K, Wienkenhöver J, Wu H, Xia X, Xie M, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JH, Zhang MT, Zhang XB, Zhang Z, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zimmermann N, Zuccon P, and Zurbach C

Abstract

Precision measurements by the Alpha Magnetic Spectrometer on the International Space Station of the primary cosmic-ray electron flux in the range 0.5 to 700 GeV and the positron flux in the range 0.5 to 500 GeV are presented. The electron flux and the positron flux each require a description beyond a single power-law spectrum. Both the electron flux and the positron flux change their behavior at ∼30  GeV but the fluxes are significantly different in their magnitude and energy dependence. Between 20 and 200 GeV the positron spectral index is significantly harder than the electron spectral index. The determination of the differing behavior of the spectral indices versus energy is a new observation and provides important information on the origins of cosmic-ray electrons and positrons.

Published
2014
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41. Removal of dimethyl sulfide by the combination of non-thermal plasma and biological process.

Author

Wei ZS, Li HQ, He JC, Ye QH, Huang QR, and Luo YW

Subjects
Biodegradation, Environmental, Bioreactors, Carbon chemistry, Denaturing Gradient Gel Electrophoresis, Equipment Design, Filtration, Gases, Methanol chemistry, Oxygen chemistry, Polymerase Chain Reaction, Sulfates chemistry, Sulfur chemistry, Sulfur Oxides chemistry, Time Factors, Air Pollutants, Ozone, Plasma Gases, Sulfides analysis, Sulfides chemistry
Abstract

A bench scale system integrated with a non-thermal plasma (NTP) and a biotricking filtration (BTF) unit for the treatment of gases containing dimethyl sulfide (DMS) was investigated. DMS removal efficiency in the integrated system was up to 96%. Bacterial communities in the BTF were assessed by PCR-DGGE, which play the dominant role in the biological processes of metabolism, sulfur oxidation, sulfate-reducing and carbon oxidation. The addition of ozone from NTP made microbial community in BTF more complicated and active for DMS removal. The NTP oxidize DMS to simple compounds such as methanol and carbonyl sulfide; the intermediate organic products and DMS are further oxidized to sulfate, carbon dioxide, water vapors by biological degradation. These results show that NTP-BTF is achievable and open new possibilities for applying the integrated with NTP and BTF to odour gas treatment., (Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Published
2013
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42. First result from the Alpha Magnetic Spectrometer on the International Space Station: precision measurement of the positron fraction in primary cosmic rays of 0.5-350 GeV.

Author

Aguilar M, Alberti G, Alpat B, Alvino A, Ambrosi G, Andeen K, Anderhub H, Arruda L, Azzarello P, Bachlechner A, Barao F, Baret B, Barrau A, Barrin L, Bartoloni A, Basara L, Basili A, Batalha L, Bates J, Battiston R, Bazo J, Becker R, Becker U, Behlmann M, Beischer B, Berdugo J, Berges P, Bertucci B, Bigongiari G, Biland A, Bindi V, Bizzaglia S, Boella G, de Boer W, Bollweg K, Bolmont J, Borgia B, Borsini S, Boschini MJ, Boudoul G, Bourquin M, Brun P, Buénerd M, Burger J, Burger W, Cadoux F, Cai XD, Capell M, Casadei D, Casaus J, Cascioli V, Castellini G, Cernuda I, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen CR, Chen H, Cheng GM, Chen HS, Cheng L, Chernoplyiokov N, Chikanian A, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Commichau V, Consolandi C, Contin A, Corti C, Costado Dios MT, Coste B, Crespo D, Cui Z, Dai M, Delgado C, Della Torre S, Demirkoz B, Dennett P, Derome L, Di Falco S, Diao XH, Diago A, Djambazov L, Díaz C, von Doetinchem P, Du WJ, Dubois JM, Duperay R, Duranti M, D'Urso D, Egorov A, Eline A, Eppling FJ, Eronen T, van Es J, Esser H, Falvard A, Fiandrini E, Fiasson A, Finch E, Fisher P, Flood K, Foglio R, Fohey M, Fopp S, Fouque N, Galaktionov Y, Gallilee M, Gallin-Martel L, Gallucci G, García B, García J, García-López R, García-Tabares L, Gargiulo C, Gast H, Gebauer I, Gentile S, Gervasi M, Gillard W, Giovacchini F, Girard L, Goglov P, Gong J, Goy-Henningsen C, Grandi D, Graziani M, Grechko A, Gross A, Guerri I, de la Guía C, Guo KH, Habiby M, Haino S, Hauler F, He ZH, Heil M, Heilig J, Hermel R, Hofer H, Huang ZC, Hungerford W, Incagli M, Ionica M, Jacholkowska A, Jang WY, Jinchi H, Jongmanns M, Journet L, Jungermann L, Karpinski W, Kim GN, Kim KS, Kirn T, Kossakowski R, Koulemzine A, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Laudi E, Laurenti G, Lauritzen C, Lebedev A, Lee MW, Lee SC, Leluc C, León Vargas H, Lepareur V, Li JQ, Li Q, Li TX, Li W, Li ZH, Lipari P, Lin CH, Liu D, Liu H, Lomtadze T, Lu YS, Lucidi S, Lübelsmeyer K, Luo JZ, Lustermann W, Lv S, Madsen J, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masciocchi F, Masi N, Maurin D, McInturff A, McIntyre P, Menchaca-Rocha A, Meng Q, Menichelli M, Mereu I, Millinger M, Mo DC, Molina M, Mott P, Mujunen A, Natale S, Nemeth P, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oh S, Oliva A, Palmonari F, Palomares C, Paniccia M, Papi A, Park WH, Pauluzzi M, Pauss F, Pauw A, Pedreschi E, Pensotti S, Pereira R, Perrin E, Pessina G, Pierschel G, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pochon J, Pohl M, Poireau V, Porter S, Pouxe J, Putze A, Quadrani L, Qi XN, Rancoita PG, Rapin D, Ren ZL, Ricol JS, Riihonen E, Rodríguez I, Roeser U, Rosier-Lees S, Rossi L, Rozhkov A, Rozza D, Sabellek A, Sagdeev R, Sandweiss J, Santos B, Saouter P, Sarchioni M, Schael S, Schinzel D, Schmanau M, Schwering G, Schulz von Dratzig A, Scolieri G, Seo ES, Shan BS, Shi JY, Shi YM, Siedenburg T, Siedling R, Son D, Spada F, Spinella F, Steuer M, Stiff K, Sun W, Sun WH, Sun XH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tassan-Viol J, Ting SC, Ting SM, Titus C, Tomassetti N, Toral F, Torsti J, Tsai JR, Tutt JC, Ulbricht J, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vargas Trevino M, Vaurynovich S, Vecchi M, Vergain M, Verlaat B, Vescovi C, Vialle JP, Viertel G, Volpini G, Wang D, Wang NH, Wang QL, Wang RS, Wang X, Wang ZX, Wallraff W, Weng ZL, Willenbrock M, Wlochal M, Wu H, Wu KY, Wu ZS, Xiao WJ, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JG, Zhang Z, Zhang MM, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zuccon P, and Zurbach C

Abstract

A precision measurement by the Alpha Magnetic Spectrometer on the International Space Station of the positron fraction in primary cosmic rays in the energy range from 0.5 to 350 GeV based on 6.8 × 10(6) positron and electron events is presented. The very accurate data show that the positron fraction is steadily increasing from 10 to ∼ 250  GeV, but, from 20 to 250 GeV, the slope decreases by an order of magnitude. The positron fraction spectrum shows no fine structure, and the positron to electron ratio shows no observable anisotropy. Together, these features show the existence of new physical phenomena.

Published
2013
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44. Conformationally restricted and conformationally defined tyramine analogues as inhibitors of phenylethanolamine N-methyltransferase.

Author

Ye QH and Grunewald GL

Subjects
Molecular Conformation, Structure-Activity Relationship, Phenylethanolamine N-Methyltransferase antagonists & inhibitors, Tyramine analogs & derivatives
Abstract

In a search for a selective inhibitor for the epinephrine synthesizing enzyme phenylethanolamine N-methyltransferase (PNMT; EC 2.1.1.28), phenolic 2-aminotetralins (12-15 as conformationally restricted analogues of tyramine) and phenolic benzobicyclo[3.2.1]octylamines (22-24 as conformationally defined analogues of tyramine) were used to gain information about the binding interactions of the catecholic hydroxyl groups in the natural substrate norepinephrine at the active site of PNMT. In addition, these analogues provided information about the effects of conformational flexibility on active-site interaction of the aminoethyl side chain in phenolic phenylethylamines that may aid in learning the manner in which norepinephrine binds at the active site of PNMT. Analogues 22-24 were synthesized by a nine-step sequence, in which a Friedel-Crafts type intramolecular cyclization was the key step in the construction of the benzobicyclo[3.2.1]octane skeleton. p-Tyramine (10, Ki = 294 microM) was more potent than phenylethylamine (1, Ki = 854 microM) but m-tyramine (9, Ki = 1250 microM) was less potent than phenylethylamine as an inhibitor of PNMT. Similarly, in the conformationally restricted and conformationally defined tyramine analogues (12-15 and 22-24, respectively), the analogues with the p-tyramine moiety (14, Ki = 4.7 microM; 23, Ki = 111 microM) bind to PNMT better than do the corresponding unsubstituted compounds (16, Ki = 6.8 microM; 25, Ki = 206 microM) while the analogues with the m-tyramine moiety (13, 15, 22, and 24) have a lower binding affinity than do 16 and 25. The greatly enhanced activity of the phenolic 2-aminotetralins (12-15) compared with m- and p-tyramine (9 and 10, respectively) is likely due to the restriction of the side-chain conformation. The conformationally defined analogues 22-24 were less active than the conformationally restricted ones, 12-15, although the low-energy half-chair conformation of 2-aminotetralin is defined in 22-24. The reduced activity of 22-24 compared with the activity of 12-15 is probably due to the steric hindrance from the extra bridging atoms in binding to PNMT. The interaction of the p-hydroxyl group of the tyramine moiety may involve hydrogen bonding since the corresponding methyl ethers show a greatly reduced affinity for the active site of PNMT (Ki = 34 and 389 microM for methoxy analogues 28 and 35, compared to Ki = 4.7 and 111 microM for the corresponding phenolic analogues 14 and 23).

Published
1989
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45. Stereochemical aspects of phenylethanolamine analogues as substrates of phenylethanolamine N-methyltransferase.

Author

Grunewald GL and Ye QH

Subjects
Animals, Binding Sites, Cattle, Isoelectric Point, Kinetics, Norepinephrine metabolism, Phenylpropanolamine metabolism, Stereoisomerism, Phenethylamines metabolism, Phenylethanolamine N-Methyltransferase metabolism
Abstract

Phenylethylamines and phenylethanolamines represent two major classes of ligands for the epinephrine synthesizing enzyme, phenylethanolamine N-methyltransferase (PNMT;EC 2.1.1.28). Phenylethylamines are usually competitive inhibitors and the isomers with the relative configuration as in (2S)-amphetamine (1) and (2S)-2-aminotetralin (3) are better inhibitors than their enantiomers. Phenylethanolamines are usually substrates of PNMT and the enzyme prefers the 1R isomers, such as (1R)-phenylethanolamine (5), in this class. Optically active norephedrines (7 and 8), norpseudoephedrines (9 and 10), and 2-amino-1-tetralols (13-16) were used to study the stereochemical requirements of phenylethanolamines for PNMT active site binding. Although the norephedrines (7 and 8) and the norpseudoephedrines (9 and 10) were poorer ligands for PNMT than were the 2-amino-1-tetralols (13-16), (1R,2S)-(-)-norephedrine (7) showed some activity as a PNMT substrate (Km = 1310 microM, Vmax = 0.22, 100 x Vmax/Km = 0.017). In the 2-amino-1-tetralols (13-16), the isomers with the 2S configuration (13 and 15) showed higher affinity to PNMT (13, Km = 4.5 microM; 15, Ki = 4.6 microM) and those with the 1R configuration (13 and 16) were substrates for the PNMT-catalyzed methyl transfer (13, Km = 4.5 microM, Vmax = 0.16, 100 x Vmax/Km = 3.6; 16, Km = 195 microM, Vmax = 0.12, 100 x Vmax/Km = 0.062); the combination of 1R and 2S configurations, such as in (1R,2S)-2-amino-1-tetralol (13), was required for a good substrate. These stereochemical requirements derived from the norephedrines (7 and 8), the norpseudoephedrines (9 and 10), and the 2-amino-1-tetralols (13-16) complement those for phenylethylamines (1-4) and for phenylethanolamines (5 and 6) and strongly suggest that phenylethylamine inhibitors bind to PNMT in the same orientation as do phenylethanolamine substrates.

Published
1988
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