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154 results on '"Ye, Jiajun"'

1. Research Progress on Harmless Treatment and Recycling of SF6 for GIS Equipment

Author

Wang, Jingrui, He, Chen, Wu, Yufei, Tang, Sheng, Ye, Jiajun, Wang, Jian, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Yang, Qingxin, editor, and Li, Jian, editor

Published
2025
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2. A ReaxFF MD Research in Predicting Corona Resistance of Fluorinated Epoxy in SF6

Author

Wang, Jingrui, Wang, Huihui, Wu, Lin, Yang, Meng, Peng, Jing, Ye, Jiajun, Wang, Jian, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Yang, Qingxin, editor, and Li, Jian, editor

Published
2025
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8. Review and Suggestions for the Preparation and Quality Control of 68Ga-PSMA-11 Injection

Author

YE Jiajun;ZHANG Mingru;WANG Jia;ZHU Zifan;KANG Fei;YANG Weidong;WANG Jing

Subjects
68ga-psma-11 injection, 68ge/68ga generator, preparation process, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

In this study, a standardized preparation process for 68Ga-PSMA-11 injection was developed by optimizing the labeling conditions, and the quality control standards of 68Ga-PSMA-11 injection applicable to our institution were formulated by combining domestic and international pharmacopoeias. Reviewing the preparation and quality control results of a total of 316 batches of 68Ga-PSMA-11 injections from 2020—2022, it was found that all batches were successfully prepared to obtain 68Ga-PSMA-11 injections, and the quality control results were in full compliance with the proposed standards. The labeling rate of 68Ga-PSMA-11 was （85.3±11.4）%, and it was decreased significantly with increasing total elution volume of 68Ge/68Ga generator, while the elution interval time had little effect on the labeling rate. This study is expected to guide nuclear medicine practitioners to standardize the preparation and quality control process of 68Ga-PSMA-11 injection, thus improving the quality and safety of the drug, and providing a reference for related industry standards.

Published
2023
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12. Extending Shelf‐Life of Two‐Step Method Precursor Solutions through Targeted Regulation for Highly Efficient and Reproducible Perovskite Solar Cells.

Author

Ye, Jiajun, Sheng, Wangping, He, Jiacheng, Zhong, Yang, Liu, Yikun, Liu, Kaikai, Tan, Licheng, and Chen, Yiwang

Subjects
*SOLUTION (Chemistry), *SOLAR cells, *PROTOGENIC solvents, *LEAD iodide, *OXIDATION-reduction reaction
Abstract

Precursor solution aging process can cause significant influence on the photovoltaic performance of perovskite solar cells (PVSCs). Notably, we first observe that the aging phenomenon is more severe in the precursor of two‐step sequential method compared to that in one‐step method due to that the protic solvent isopropanol facilitates amine‐cation side reaction and iodide ions oxidation. Herein, we report a novel approach for selectively stabilizing both organic amine salt and lead iodide (PbI2) precursor solutions in two‐step method. The introduction of benzene‐1,3‐dithiol into organic amine salt solution can mitigate amine‐cation side reactions due to the formation of an acidic and reducing environment. Simultaneously, decamethylferrocene (FcMe10/FcMe+10) pair can act as a redox shuttle in PbI2 solution to concurrently oxidize Pb0 and reduce I2 in cyclic manner. Consequently, the PVSCs device fabricated from ameliorative precursor solutions demonstrates superior power conversion efficiency of 25.31 %, retaining 95 % of its efficiency after 21 days of solution aging. Moreover, the unencapsulated devices maintain 85 % of primitive efficiency for 1500 h at maximum power point tracking under continuous illumination. This work establishes a fundamental guidance and scientific direction for the stabilization of two‐step perovskite precursor solutions. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Surgical evidence-based comparison of [68Ga]Ga-FAPI-04 PET and MRI-DWI for assisting debulking surgery in ovarian cancer patients.

Author

Li, Xiang, Lv, Xiaohui, Quan, Zhiyong, Han, Tingting, Tang, Yongqiang, Liu, Ying, Wang, Mengxin, Li, Guiyu, Ye, Jiajun, Wang, Jingyi, Lan, Xiaoli, Zhang, Xiao, Li, Mengting, Liu, Shujuan, Kang, Fei, and Wang, Jing

Subjects
OVARIAN cancer, DIFFUSION magnetic resonance imaging, CANCER patients, ONCOLOGIC surgery, POSITRON emission tomography, MAGNETIC resonance imaging
Abstract

Purpose: Imaging assessment of abdominopelvic tumor burden is crucial for debulking surgery decision in ovarian cancer patients. This study aims to compare the efficiency of [68Ga]Ga-FAPI-04 FAPI PET and MRI-DWI in the preoperative evaluation and its potential impact to debulking surgery decision. Methods: Thirty-six patients with suspected/confirmed ovarian cancer were enrolled and underwent integrated [68Ga]Ga-FAPI-04 PET/MRI. Nineteen patients (15 stage III–IV and 4 I–II stage) who underwent debulking surgery were involved in the diagnostic efficiency analysis. The images of [68Ga]Ga-FAPI-04 PET and MRI-DWI were visually analyzed respectively. Immunohistochemistry on FAP was performed in metastatic lesions to investigate the radiological missing of [68Ga]Ga-FAPI-04 PET as well as its different performance in primary debulking surgery (PDS) and interval debulking surgery (IDS) patients. Potential imaging impact on management was also studied in 35 confirmed ovarian cancer patients. Results: [68Ga]Ga-FAPI-04 PET displayed higher sensitivity (76.8% vs.59.9%), higher accuracy (84.9% vs. 80.7%), and lower missing rate (23.2% vs. 40.1%) than MRI-DWI in detecting abdominopelvic metastasis. The diagnostic superiority of [68Ga]Ga-FAPI-04 PET is more obvious in PDS patients but diminished in IDS patients. [68Ga]Ga-FAPI-04 PET outperformed MRI-DWI in 70.8% abdominopelvic regions (17/24), which contained seven key regions that impact the resectability and surgical complexity. MRI-DWI hold advantage in the peritoneal surface of the bladder and the central tendon of the diaphragm. Of the contradictory judgments between the two modalities (14.9%), [68Ga]Ga-FAPI-04 PET correctly identified more lesions, particularly in PDS patients (73.8%). In addition, FAP expression was independent of lesion size and decreased in IDS patients. [68Ga]Ga-FAPI-04 PET changed 42% of surgical planning that was previously based on MRI-DWI. Conclusion: [68Ga]Ga-FAPI-04 PET is more efficient in assisting debulking surgery in ovarian cancer patients than MRI-DWI. Integrated [68Ga]Ga-FAPI-04 PET/MR imaging is a potential method for planning debulking surgery in ovarian cancer patients. [ABSTRACT FROM AUTHOR]

Published
2024
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23. PI-RADS-based segmented threshold of PSMA-PET SUVmax is better than traditional fixed threshold for diagnosing clinically significant prostate cancer especially for PI-RADS 3 lesions

Author

Meng, Xiaoli, primary, Ma, Wenhui, additional, Zhang, Jingliang, additional, Quan, Zhiyong, additional, Zhang, Mingru, additional, Ye, Jiajun, additional, Shu, Jun, additional, Ren, Jing, additional, Qin, Weijun, additional, Kang, Fei, additional, and Wang, Jing, additional

Published
2023
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29. 68Ga-FAPI-04 PET for Surveillance of Anastomotic Recurrence in Postoperative Patients with Gastrointestinal Cancer: a Comparative Study with 18F-FDG PET.

Author

Li, Xiang, Ma, Wenhui, Wang, Min, Quan, Zhiyong, Zhang, Mingru, Ye, Jiajun, Li, Guiyu, Zhou, Xiang, Ma, Taoqi, Wang, Junling, Yang, Weidong, Nie, Yongzhan, Wang, Jing, and Kang, Fei

Subjects
GASTROINTESTINAL cancer, DISEASE relapse, CANCER patients, SURGICAL site, COMPUTED tomography, POSITRON emission tomography, ENDOSCOPIC ultrasonography
Abstract

Purpose: This study aims to compare the diagnostic efficacy of 68Ga-FAPI-04 PET and 18F-FDG PET for detecting anastomotic recurrence in postoperative patients with gastrointestinal cancer, and to characterize the signal pattern over time at surgical wounds on both PET imaging. Methods: Gastrointestinal cancer patients who planned to 68Ga-FAPI-04 and 18F-FDG PET/CT imaging for postoperative surveillance were involved. The SUVmax at surgical wounds were assessed. Endoscopic pathology confirmed anastomotic recurrence or it was ruled out by imaging and clinical follow-up. The sensitivity, specificity, positive and negative predictive values (PPV and NPV), and accuracy of the two PET imaging in detecting anastomotic recurrence were compared. Relationships between tracer uptake at surgical wounds and postoperative time were also analyzed. Results: Compared with non-recurrent patients, the recurrent patients exhibited a significantly higher anastomotic SUVmax on 68Ga-FAPI-04 PET (SUVmax: 9.92 ± 4.36 vs. 2.81 ± 1.86, P = 0.002). Sensitivity, specificity, PPV, NPV, and accuracy of detecting anastomotic recurrence were 100.0%, 87.3%, 41.7%, 100.0%, and 88.3% for 68Ga-FAPI-04 PET, and 60.0%, 81.8%, 23.1%, 95.7%, and 80.0% for 18F-FDG PET, respectively. Although 68Ga-FAPI-04 PET signal at surgical wounds showed a slight trend to decrease with time, no statistical difference was observed over months post-surgery (P > 0.05). Conclusions: Both tracers displayed high NPVs in identifying anastomotic recurrence with a higher sensitivity to 68Ga-FAPI-04. Tracer uptake at anastomotic sites does not decrease significantly over time, which results in low PPVs for both PET. Therefore, it is difficult to differentiate anastomotic recurrence from inflammation on either PET imaging. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Head-to-Head Comparison of 68Ga-PSMA-11 with 68Ga-P137 in Patients with Suspected Prostate Cancer

Author

Han, Tingting, Quan, Zhiyong, Wang, Min, Meng, Xiaoli, Zhang, Mingru, Ye, Jiajun, Li, Guiyu, Wang, Jing, and Kang, Fei

Abstract

P137 is a novel oxalyldiaminopropionic acid-urea-based prostate-specific membrane antigen (PSMA) targeting agent. This study compared the uptake patterns of 68Ga-P137 and the FDA-approved PET tracer 68Ga-PSMA-11 for diagnosing prostate cancer (PCa). Sixteen patients suspected of PCa were scanned by 68Ga-PSMA-11 and 68Ga-P137 PET/CT, respectively, followed by prospective analysis. The tumor-to-background ratio was calculated using normal prostate tissue, blood pool, muscle, and urine as backgrounds. Pathology or follow-up results were used to analyze uptake patterns of benign/malignant lesions and various organs. Thirteen patients were diagnosed with PCa and three with benign prostate diseases (BPD). The number and location of primary lesions, lymph node metastasis (LNM) (n = 25), bone metastasis (n = 30), and liver metastasis (n = 3) detected by the two tracers were identical. Maximum standardized uptake value (SUVmax), tumor/normal prostate ratio, as well as semiquantitative miPSMA-ES and PRIMARY diagnostic scores (Pall >0.05) showed similar uptake levels of primary lesions between 68Ga-P137 and 68Ga-PSMA-11. Compared to 68Ga-P137, the SUVmax of 68Ga-PSMA-11 was significantly higher for bone metastasis, LNM, and liver metastasis (14.9 ± 7.2 vs 9.1 ± 4.4, 14.4 ± 5.0 vs 7.5 ± 2.4, 13.9 ± 2.0 vs 8.8 ± 2.4, Pall <0.05). One-hour postinjection, SUVmax of the duodenum (9.4 ± 2.1 vs 16.2 ± 6.1), kidney (19.4 ± 4.3 vs 45.6 ± 20.9), and urine (14.1 ± 7.1 vs 42.1 ± 25.9) were significantly lower for 68Ga-P137 than for 68Ga-PSMA-11 (Pall <0.05), whereas the radioactivity accumulation of blood pool and muscle (3.9 ± 0.5 vs 1.6 ± 0.4, 1.0 ± 0.1 vs 0.6 ± 0.1, Pall <0.05) of 68Ga-P137 was significantly higher than 68Ga-PSMA-11. The uptake level of 68Ga-P137 has no significant difference from that of 68Ga-PSMA-11 in prostate primary lesions, and their imaging performances are visually equivalent for both primary and metastatic lesions, despite a higher blood pool and muscle background and a lower uptake in metastatic lesions. Due to the lower urine excretion of 68Ga-P137, primary prostate lesions near the urine can potentially be displayed clearer than 68Ga-PSMA-11.

Published
2023
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31. 68Ga-FAPI-04 PET for surveillance of anastomotic recurrence in postoperative patients with gastrointestinal cancer: a comparative study with 18F-FDG PET

Author

Li, Xiang, primary, Ma, Wenhui, additional, Wang, Min, additional, Quan, Zhiyong, additional, Zhang, Mingru, additional, Ye, Jiajun, additional, Li, Guiyu, additional, Zhou, Xiang, additional, Ma, Taoqi, additional, Wang, Junling, additional, Yang, Weidong, additional, Nie, Yongzhan, additional, Wang, Jing, additional, and Kang, Fei, additional

Published
2022
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40. Additional file 1 of Evaluation of the stability of cucurbit[8]uril-based ternary host−guest complexation in physiological environment and the fabrication of a supramolecular theranostic nanomedicine

Author

Wu, Han, Chen, Zuobing, Qi, Shaolong, Bai, Bing, Ye, Jiajun, Wu, Dan, Shen, Jie, Kang, Fei, and Yu, Guocan

Abstract

Additional file 1: Scheme S1. Synthetic routes to PCL-MV and Nap-PEG. Scheme S2. Synthetic routes to Nap-DFO. Fig. S1. 1H NMR spectrum (400 MHz, CDCl3, room temperature) of PCL-Br. Fig. S2. GPC curve of PCL-Br. Fig. S3. 1H NMR spectrum (400 MHz, CDCl3, room temperature) of PCL-MV. Fig. S4. GPC curve of PCL-MV. Fig. S5. 1H NMR spectrum (400 MHz, CDCl3, room temperature) of Nap-PEG. Fig. S6. GPC curve of Nap-PEG. Fig. S7. 1H NMR spectrum (400 MHz, CDCl3, room temperature) of Nap-Boc. Fig. S8. 13C NMR spectrum (100 MHz, CDCl3, room temperature) of Nap-Boc. Fig. S9. ESI IT-TOF results of Nap-Boc. [M + Na]+ = 340.1494. Fig. S10. 1H NMR spectrum (400 MHz, DMSO-d6, room temperature) of Nap-NH2. Fig. S11. 13C NMR spectrum (100 MHz, DMSO-d6, room temperature) of Nap-NH2. Fig. S12. ESI IT-TOF results of Nap-NH2. [M + H]+ = 218.1142. Fig. S13. 1H NMR spectrum (400 MHz, DMSO-d6, room temperature) of Nap-DFO. Fig. S14. 13C NMR spectrum (100 MHz, DMSO-d6, room temperature) of Nap-DFO. Fig. S15. ESI IT-TOF result of Nap-DFO. [M – H]– = 775.3225. Fig. S16. 1H NMR spectra of a Nap-PEG, b Nap-PEG + CB[8] and c CB[8] in D2O. Fig. S17. CLSM images of HepG2 cells cultured with DOX∙HCl for 4 h and 9 h, respectively. The right images are the enlarged ones at the same time point. Fig. S18. Cytotoxicity evaluation of CB[8] against HepG2 cells using an MTT assay. Fig. S19. Cytotoxicity evaluation of PCL-MV against HepG2 cells using an MTT assay. Fig. S20. Cytotoxicity evaluation of Nap-PEG against HepG2 cells using an MTT assay. Fig. S21. Cytotoxicity evaluation of DOX·HCl and SNM@DOX against HepG2 cells after 24 h incubation using a CCK-8 assay. Fig. S22. Release profiles of Nap-DFO from the nanoformulation in water or PBS. Fig. S23. Time-dependent biodistribution of 89Zr SNM@DOX in liver and tumor. Fig. S24. Body weight changes of the mice treated with different formulations. Fig. S25. H&E staining of the heart tissues from a healthy mouse and b the mouse treated with SNM@DOX at day 18.

Published
2021
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41. A Method for Domain Name Data Acquisition Based on Zone Transfer

Author

Ye Jiajun and Zhao Feng

Subjects
Name server, Information retrieval, Computer science, Zone file, business.industry, Domain Name System, DNS zone transfer, Server, The Internet, business, Information science, Domain (software engineering)
Abstract

The domain name system is an important infrastructure of the Internet. In order to effectively prevent the management and technical risks faced by the domain name system, there is an urgent need to obtain relatively complete Internet domain name data to provide basic data support. However, due to a series of restrictive factors such as non-enumerable domain name space, scattered domain name data storage, and restricted access to registry resources, the acquisition of Internet domain name data has become a challenge. We propose a domain name acquisition method based on zone transfer: the authoritative DNS master name server and slave name server usually maintain the function of the entire domain based on the same zone file. We try to find every authoritative domain name server that provides domain name services. The zone transfer obtains the domain name data information of the corresponding domain. We explored the way to implement the method and conducted experimental evaluation. The method has shortcomings in terms of effectiveness and ability, but a considerable amount of domain name data can be obtained to support the construction of a mapping database between global domain names and IP addresses.

Published
2020
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