1. Prevention of Intra-abdominal Adhesions by Electrical Stimulation
- Author
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Loreto B. Feril, Timur Saliev, Ildar Fakhradiyev, Zhandos Serikpayev, Ydyrys A. Almabayev, Baimakhan Tanabayev, Maral Yergazina, and Aygul Almabayeva
- Subjects
Electrical muscle stimulation ,medicine.medical_treatment ,Adhesion (medicine) ,Biocompatible Materials ,Tissue Adhesions ,Stimulation ,03 medical and health sciences ,chemistry.chemical_compound ,Postoperative Complications ,0302 clinical medicine ,Muscular Diseases ,Abdominal muscles ,Hyaluronic acid ,Animals ,Medicine ,Hyaluronic Acid ,Electric stimulation ,Abdominal Muscles ,Transdermal ,business.industry ,Membranes, Artificial ,medicine.disease ,Combined Modality Therapy ,Electric Stimulation ,chemistry ,030220 oncology & carcinogenesis ,Anesthesia ,Models, Animal ,030211 gastroenterology & hepatology ,Surgery ,Rabbits ,business ,Abdominal surgery - Abstract
The study investigated the ability of transdermal electric stimulation to prevent the formation of intra-abdominal adhesions in the combination with Seprafilm® (anti-adhesive agent). One hundred and twenty-eight (128) rabbits were subjected to a surgical procedure to simulate the adhesion processes. After the simulation, the animals were divided into 4 groups (32 animals each), depending on the application of the methods of prevention: (1) control group (no anti-adhesives or electro-stimulation) (CG); (2) comparison group (applications of Seprafilm®) (SF); (3) comparison group 2 (transdermal electric stimulation of the abdominal muscles) TES; (4) group (transdermal electric stimulation + Seprafilm®) (TES + SF). We observed that the application of the Seprafilm® alone led to a significant decrease in the adhesive process compared to the control group (CG) (p
- Published
- 2020