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Your search keyword '"Yazan Mahmoud"' showing total 3 results
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3 results on '"Yazan Mahmoud"'

1. Cephalometric Evaluation of Pharyngeal Airway Space among Different Skeletal Malocclusions in United Arab Emirates Residents: A Cross-Sectional Study

Author

Jensyll Rodrigues, Ab Rani Samsudin, Ahmed Ismail, Saad Al Bayatti, Snigdha Pattanaik, Vinayak Kamath, Vellore Kannan Gopinath, Yazan Mahmoud, and Shishir Ram Shetty

Subjects
Orthodontics, Cephalometry, Pharynx, Dimensional Measurement Accuracy, Dentistry, RK1-715
Abstract

Objective: To determine the relationship between skeletal malocclusion and upper pharyngeal airway space in the United Arab Emirates population using linear cephalometric measurements. Material and Methods: A retrospective cross-sectional study was performed on lateral cephalogram radiographs acquired from the University Dental Hospital. Through convenience sampling, 70 lateral cephalograms were selected from 200, meeting the inclusion criteria for this study. Study subjects were divided into three groups: Class I (n=25), Class II (n=21), and Class III (n=24). The study groups were compared based on the linear upper pharyngeal airway space measurements. Results: The three groups observed significant differences between the upper pharyngeal airway measurements. No differences in parameters were noted within the male and female study subjects. A highly significant difference (p

Published
2024

2. An Audit of the Technical Quality and Iatrogenic Errors of Root Canal Treatment by Undergraduate Dental Students at the University of Sharjah

Author

Saaid Al Shehadat, Mohamed El-Kishawi, Asma AlMudalal, Asma AlSaqer, Aya Nassar, Leena Zihlif, Yazan Mahmoud, Venkateshbabu Nagendrababu, and Thilla Sekar Vinothkumar

Subjects
General Dentistry
Abstract

Objectives The aim of this study was to determine the technical quality of root canal fillings and the presence of iatrogenic errors in the cases treated by undergraduate dental students using radiographic images. Materials and Methods This study included 480 root-filled teeth, which were evaluated using intraoral periapical radiographic images. The technical quality of obturation was assessed by observing the length, density, and taperness of the root filling. Ledges, apical transportation, fractured instruments, zipping, and root perforation were recorded as iatrogenic errors. Teeth were classified as acceptable if the technical parameters were adequate and there were no iatrogenic errors. Statistical Analysis Data were statistically analyzed using Pearson's chi-squared test. Results The quality of root filling was acceptable in 183 of the 480 teeth. The rate of acceptable quality was higher for the teeth treated by 4th-year students (41.9%) than for those treated by 5th-year students (27.4%; p = 0.004). Length and taperness were adequate in more of the patients treated by the 4th-year students (p Conclusions The technical quality of root fillings performed without iatrogenic errors by undergraduate dental students was declared acceptable in 38.1% of the assessed teeth. There was a noticeable difference in the quality of root canal treatment between the 4th- and 5th-year students. Clinical Relevance The findings demonstrate that periodic assessment of the technical quality of root filling performed by undergraduate dental students provides feedback on curriculum standards.

Published
2022
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3. Mechanisms of benzyl alcohol tolerance in Drosophila melanogaster

Author

Alhasan, Yazan Mahmoud

Subjects
Anesthetic, Anesthesia, Tolerance, Sedation, Arousal, Alcohol, Benzyl alcohol, Mushroom bodies, Ellipsoid body, Gal4, Ion channel, Slowpoke, BK, Shibire, Shi, Syx, Syntaxin, Comatose, Comt, Para, Paralytic, Larva, Drosophila, melanogaster, Homeostasis, NEM, N-ethylmaleimide, Temperature sensitive, Conditional mutants, Cell autonomous, Neuronal excitability, Resistance, Sensitization, Vesicle fusion, Vesicle recycling, Heat shock
Abstract

Proper neuronal function requires the preservation of appropriate neural excitability. An adaptive increase in neural excitability after exposure to agents that depress neuronal signaling blunts the sedative drug effects upon subsequent drug exposure. This adaptive response to drug exposure leads to changes in drug induced behaviors such as tolerance, withdrawal and addiction. Here I use Drosophila melanogaster to study the cellular and neuronal components which mediate behavioral tolerance to the anesthetic benzyl alcohol. I demonstrate that rapid tolerance to benzyl alcohol is a pharmacodynamic mechanism independent of drug metabolism. Furthermore, tolerance is a cell autonomous response which occurs in the absence of neural signaling. Using genetic and pharmacological manipulations I find the synapse to play an important role in the development of tolerance. In addition, the neural circuits that regulate arousal and sleep also alter benzyl alcohol sensitivity. Beyond previously described transcriptional mechanisms I find a post-translational role of the Ca2+-activated K+-channel, slowpoke in the development of tolerance. Finally, I explore a form of juvenile onset tolerance, which may have origins that differ from rapid tolerance. The implications of this study go beyond tolerance in Drosophila melanogaster to benzyl alcohol and can shed light on human drug tolerance, withdrawal and addiction.

Published
2009

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