20 results on '"Yawei Jia"'
Search Results
2. Events Detection and Temporal Analysis in Social Media.
- Author
-
Yawei Jia, Jing Xu 0007, Zhonghu Xu, and Kai Xing
- Published
- 2016
- Full Text
- View/download PDF
3. BOWL: Bag of Word Clusters Text Representation Using Word Embeddings.
- Author
-
Weikang Rui, Kai Xing, and Yawei Jia
- Published
- 2016
- Full Text
- View/download PDF
4. Streaming media transmission system based on crowd participatory network oriented by remote medical.
- Author
-
Lei Tan, Huiting Fan, Yawei Jia, Weikang Rui, Jing Guo, and Qing Wang
- Published
- 2015
- Full Text
- View/download PDF
5. Red Emissive Double Aza[7]helicenes with Antiaromaticity / Aromaticity Switching via the Redox‐Induced Radical Cation and Dication Species
- Author
-
Chenglong Li, Chen Zhang, Pengfei Li, Yawei Jia, Jiaxian Duan, Meiyan Liu, Niu Zhang, and Pangkuan Chen
- Subjects
General Medicine ,General Chemistry ,Catalysis - Published
- 2023
6. Oligotriarylamine-Extended Organoboranes with Tunable Electron-Donating Strength by Changing the Number of Donor Units
- Author
-
Pengfei Li, Yawei Jia, Songhe Zhang, Jiaqi Di, Niu Zhang, and Pangkuan Chen
- Subjects
Inorganic Chemistry ,Physical and Theoretical Chemistry - Abstract
Triarylborane (Ar
- Published
- 2022
7. Expanding new chemistry of aza-boracyclophanes with unique dipolar structures, AIE and redox-active open-shell characteristics
- Author
-
Yawei Jia, Pengfei Li, Kanglei Liu, Chenglong Li, Meiyan Liu, Jiaqi Di, Nan Wang, Xiaodong Yin, Niu Zhang, and Pangkuan Chen
- Subjects
General Chemistry - Abstract
We have achieved the synthesis of new B/N doped macrocycles by stitching oligoarylamine pentamers using arylborane acceptor segments. They exhibit open-shell radical species and AIE under ambient conditions.
- Published
- 2022
8. A New Platform of B/N‐Doped Cyclophanes: Access to a π‐Conjugated Block‐Type B 3 N 3 Macrocycle with Strong Dipole Moment and Unique Optoelectronic Properties
- Author
-
Pengfei Li, Daisuke Shimoyama, Niu Zhang, Yawei Jia, Guofei Hu, Chenglong Li, Xiaodong Yin, Nan Wang, Frieder Jäkle, and Pangkuan Chen
- Subjects
General Chemistry ,General Medicine ,Catalysis - Published
- 2022
9. Phytoremediation efficiency of poplar hybrid varieties with diverse genetic backgrounds in soil contaminated by multiple toxic metals (Cd, Hg, Pb, and As)
- Author
-
Mengge Li, Qimeng Heng, Chaobo Hu, Zhiyong Wang, Yawei Jiang, Xintong Wang, Xuelian He, Jean Wan Hong Yong, Turki M. Dawoud, Siddiq Ur Rahman, Junfeng Fan, and Yi Zhang
- Subjects
Populus ,Hybrid variety ,Phytoremediation ,Inter-specific hybrid ,Intra-specific hybrid ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Fifteen poplar varieties were used in a field trial to investigate the phytoremediation efficiency, stress resistance, and wood property of poplar hybrid varieties with diverse genetic backgrounds under the composite pollution of heavy metals. The coefficient of variation and clone repeatability for growth traits and Cd concentration were large. The Cd accumulation of poplar varieties 107 and QHQ reached 1.9 and 1.7 mg, respectively, followed by QHB, Ti, 69, and Pa, in which Cd accumulation reached 1.3 mg. Most of the intra-specific hybrid varieties (69, QH1, SL4, T3, and ZL46) had low Cd concentrations and small biomass, resulting in weak Cd accumulation and low phytoremediation efficiency for Cd-polluted soil. By contrast, the inter-sectional and inter-specific hybrid varieties exhibited better growth performance and accumulated higher concentrations of heavy metals than the intra-specific hybrids. The bioconcentration factor and translocation factor of Hg, As, and Pb were less than 1, indicating that poplars have low phytoremediation efficiency for these heavy metals. The hybrids between section Aigeiros and Tacamahaca (QHQ and QHB) and the inter-specific hybrid 107 within section Aigeiros were more resistant to composite heavy metal stress than the other poplar varieties were partially because of their high levels of free proline that exceeded 93 μg·g−1 FW. According to the correlation analysis of the concentrations of the different heavy metals, the poplar roots absorbed different heavy metals in a cooperative manner, indicating that elite poplar varieties with superior capacity for accumulating diverse heavy metals can be bred feasibly. Compared with the intra-specific hybrid varieties, the inter-sectional (QHQ and QHB) and inter-specific (107) hybrid varieties had higher pollution remediation efficiency, larger biomass, higher cellulose content, and lower lignin content, which is beneficial for pulpwood. Therefore, breeding and extending inter-sectional (QHQ and QHB) and inter-specific hybrid varieties can improve the phytoremediation of composite pollution.
- Published
- 2024
- Full Text
- View/download PDF
10. Prenatal p25-activated Cdk5 induces pituitary tumorigenesis through MCM2 phosphorylation-mediated cell proliferation
- Author
-
Yingwei Huang, Qiqi Wang, Weiwei Zhou, Yawei Jiang, Kai He, Wei Huang, Yating Feng, Hong Wu, Lijuan Liu, Yue Pan, Yihua Huang, Zirui Chen, Wei Li, Yaowei Huang, Guanchuan Lin, Yulong Zhang, Yongyan Ren, Kaibiao Xu, Yanlin Yu, Yuping Peng, Xinghua Pan, Suyue Pan, Hailiang Hu, and Yafang Hu
- Subjects
Cdk5 ,p25 ,Mcm2 ,Pituitary adenoma ,Single-cell sequencing ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Aberrant expression of cyclin-dependent kinase 5 (Cdk5) has been reported in pituitary adenomas. However, the role of Cdk5 in the tumorigenesis remains unclear. We show that prenatal p25-activated Cdk5 phosphorylates minichromosome maintenance protein 2 (Mcm2), enhancing minichromosome maintenance (MCM) family proteins and driving intermediate lobe-located melanotrope-originated pituitary tumorigenesis. In a mouse model with CaMKII promoter-driven transgenic induction of p25, we observed intermediate lobe-originated pituitary adenoma producing non-functional proopiomelanocortin (POMC)-derived peptides under persistent p25 overexpression. Single-cell RNA sequencing revealed Mcm2 may play an important role during tumor progression. Subsequently, Mcm2 was identified as a potential phosphorylated substrate of Cdk5, mediating the tumorous proliferation of melanotrope cells. Silencing Cdk5 or Mcm2 suppressed cell proliferation and colony formation in the 293T cell lines. Therefore, our findings provide a new mouse model of intermediate lobe-originated pituitary adenoma induced by p25/Cdk5 and unveil a previously unappreciated role of Cdk5 and Mcm2 in pituitary adenoma tumorigenesis.
- Published
- 2024
- Full Text
- View/download PDF
11. Spatially nonuniformly correlated vortex beams and their arrays
- Author
-
Zhangrong Mei, Yawei Jiang, and Yonghua Mao
- Subjects
Spatially nonuniformly correlations ,Vortex beam ,Beam arrays ,Propagation ,Physics ,QC1-999 - Abstract
We introduce a class of partially coherent sources with spatially nonuniformly correlation properties and an off-axis helicoidal phase. It is shown that the unique correlation and phase properties of such sources lead to radiated fields with extraordinary propagation characteristics, such as dark hollow with zero central intensity, self-focusing and lateral self-shifting light intensity. Based on such novel random sources, two types of nonuniformly correlated vortex beam arrays with radial and rectangular symmetry are explored. Analytical and numerical investigations for the evolutions of such light fields are made by the model decomposition representation of correlation function and fast Fourier transform method. The results demonstrate new opportunities for modeling off-axis self-focusing vortex beams and other beam shaping applications by joint modulation of coherence and phase.
- Published
- 2024
- Full Text
- View/download PDF
12. MiR-216b suppresses cell proliferation, migration, invasion, and epithelial–mesenchymal transition by regulating FOXM1 expression in human non-small cell lung cancer
- Author
-
Lei Wang, Xiangyang Du, Yansen Wang, Yanfen Yao, Lidong Wang, and Yawei Jia
- Subjects
0301 basic medicine ,Reporter gene ,medicine.diagnostic_test ,Cell growth ,Cell migration ,Biology ,medicine.disease ,OncoTargets and Therapy ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Oncology ,Western blot ,Cell culture ,030220 oncology & carcinogenesis ,Cancer research ,medicine ,FOXM1 ,Pharmacology (medical) ,Epithelial–mesenchymal transition ,Lung cancer - Abstract
Lidong Wang,1 Yansen Wang,1 Xiangyang Du,1 Yanfen Yao,2 Lei Wang,1 Yawei Jia31Department of Respiration, Shandong Provincial Third Hospital, Jinan 250031, Shandong, People’s Republic of China; 2Department of Intensive Care Unit, Shandong Provincial Third Hospital, Jinan 250031, Shandong, People’s Republic of China; 3Department of Occupational Pulmonary Disease, Shandong Academy of Occupational Health and Occupational Medicine, Jinan 250002, Shandong, People’s Republic of ChinaBackground/aims: MiR-216b and forkhead box M1 (FOXM1) were demonstrated to exert their biological effects on the development and progression of tumors. This study aimed to investigate the expression and role of miR-216b and FOXM1 in tissues and cell lines of non-small cell lung cancer (NSCLC).Methods: The expressions of miR-216b and FOXM1 in NSCLC tissues and cells were detected by qRT-PCR and Western blot analysis. Cell proliferation was measured by CCK-8 assay. Cell migration and invasion were confirmed by Transwell assay. Finally, the bioinformatics and dual-luciferase reporter assay were conducted to validate the relationship of miR-216b and FOXM1.Results: Compared with normal tissues and cells, the expression of miR-216b was obviously decreased in NSCLC tissues and cells. However, the expressions of FOXM1 mRNA and protein were significantly increased, and negatively correlated with the expression of miR-216b. Multivariate Cox’s regression analysis suggested that miR-216b or FOXM1 expression was an independent prognostic factor for patients with NSCLC. MiR-216b overexpression remarkably repressed cell proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT) of NSCLC cells. The bioinformatics and dual-luciferase reporter assay validated that the 3ʹ-untranslated region (3ʹ-UTR) of FOXM1 mRNA was indeed a direct target of FOXM1. In vitro, overexpression of FOXM1 partially eliminated inhibitory effects of miR-216b on cell proliferation, migration, and invasion, whereas inhibition of FOXM1 contributed to inhibitory effects mediated by miR-216b.Conclusion: MiR-216b inhibits cell proliferation, migration, invasion, and EMT by targeting the expression of FOXM1 in human NSCLC. These findings suggested a potential therapeutic role of miR-216b in patients of NSCLC.Keywords: MiR-216b, FOXM1, NSCLC, suppressor 
- Published
- 2019
13. EventGraph Based Events Detection in Social Media
- Author
-
Yawei Jia, Yongjiao Liu, and Jianbiao He
- Subjects
Computer science ,Graph based ,Graph (abstract data type) ,Social media ,Data mining ,computer.software_genre ,computer - Abstract
In the past few years, research about event detection has been devoted to a lot. In this paper, we propose an efficient method to detect hot events that spread within social media. Specifically, we build a directed weighted graph of words named EventGraph, in which events are embedded in the form of sub-graphs or communities. Lastly, we put forward a key node based event community detection method, which improve the efficiency of graph based event detection algorithms.
- Published
- 2018
14. Social relation extraction with improved distant supervised and word embedding features
- Author
-
Jinwen Liu, Weikang Rui, Liping Zhang, and Yawei Jia
- Subjects
Word embedding ,business.industry ,Computer science ,Feature extraction ,Context (language use) ,02 engineering and technology ,010501 environmental sciences ,Machine learning ,computer.software_genre ,Semantics ,01 natural sciences ,Relationship extraction ,Knowledge-based systems ,Information extraction ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,The Internet ,Chinese language ,Artificial intelligence ,business ,F1 score ,computer ,Natural language processing ,0105 earth and related environmental sciences - Abstract
With the rapid development of Internet, how to extract personal relations from Internet has become an important research topic in information extraction. However, current relation extraction researches mainly focus on the processing of English language, the researches focus on Chinese are less. At the same time, there are two main problems in current personal relation extraction approaches: 1) it is difficult to get a large amount of high quality training data without manually label effort; 2) the performance of personal relation extraction from Chinese is unsatisfactory. To solve the first problem, we propose an improved distant supervision method which is applied to Chinese language and can label large-scale of high quality training data automatically. To solve the second problem, we extract three features based on word embedding and combine them with the basic features. In the experiment, the improved distant supervision methods improve the quality of training data significantly. And the word embedding features improve the average F1 score by 4% than the basic features.
- Published
- 2016
15. Unsupervised feature selection for text classification via word embedding
- Author
-
Yawei Jia, Jinwen Liu, and Weikang Rui
- Subjects
Training set ,Word embedding ,Computer science ,business.industry ,Feature extraction ,Feature selection ,Pattern recognition ,02 engineering and technology ,Mutual information ,Semantics ,Electronic mail ,Text mining ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,Vector space model ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,Word (computer architecture) - Abstract
The key of big text documents data analysis is to classify those text documents. To classify those text documents, it is necessary to represent those text documents as vectors which is vector space model (VSM). A powerful vector space model should remain the classification information with dimensions as little as possible. To achieve that, it is important to select most effective features for text classification. Unlike the supervised selection method which utilizes the category information in the training data, we propose an unsupervised feature selection method. Our method requires no category information which makes our method has more application scenarios as the labeled data is expensive and inaccurate. Unlike other unsupervised methods, our method utilizes word embedding to find the words with similar semantic meaning. The word embedding maps the words into vectors and remains the semantic relationships between words. We select the most representative word on behalf of the words with similar semantic meaning because it is redundant to include all those words as features. We demonstrate on Reuters-21578 dataset, that our method outperforms other methods. Especially, our method has great advantage when select limited features.
- Published
- 2016
16. Events Detection and Temporal Analysis in Social Media
- Author
-
Kai Xing, Zhonghu Xu, Yawei Jia, and Jing Xu
- Subjects
Computer science ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Co-occurrence ,Graph (abstract data type) ,Social media ,Directed graph ,Data mining ,computer.software_genre ,computer - Abstract
In the past few years, event detection has drawn a lot of attention. We proposed an efficient method to detect event in this paper. An event is defined as a set of descriptive, collocated keywords in this paper. Intuitively, documents that describe the same event will contain similar sets of keywords. Individual events will form clusters in the graph of keywords for a document collection. We built a network of keywords based on their co-occurrence in documents. We proposed an efficient method which create a keywords weight directed graph named KeyGraph and use community detection method to discover events. Clump of keywords describing an event can be used to analyse the trend of the event. The accuracy of detecting events is over eighty percents with our method.
- Published
- 2016
17. BOWL: Bag of Word Clusters Text Representation Using Word Embeddings
- Author
-
Yawei Jia, Weikang Rui, and Kai Xing
- Subjects
business.industry ,Computer science ,Representation (systemics) ,02 engineering and technology ,010501 environmental sciences ,computer.software_genre ,01 natural sciences ,ComputingMethodologies_PATTERNRECOGNITION ,Semantic similarity ,Bag-of-words model ,Simple (abstract algebra) ,Similarity (psychology) ,0202 electrical engineering, electronic engineering, information engineering ,Benchmark (computing) ,020201 artificial intelligence & image processing ,Artificial intelligence ,Cluster analysis ,business ,computer ,Word (computer architecture) ,Natural language processing ,0105 earth and related environmental sciences - Abstract
The text representation is fundamental for text mining and information retrieval. The Bag Of Words (BOW) and its variants (e.g. TF-IDF) are very basic text representation methods. Although the BOW and TF-IDF are simple and perform well in tasks like classification and clustering, its representation efficiency is extremely low. Besides, word level semantic similarity is not captured which results failing to capture text level similarity in many situations. In this paper, we propose a straightforward Bag Of Word cLusters (BOWL) representation for texts in a higher level, much lower dimensional space. We exploit the word embeddings to group semantically close words and consider them as a whole. The word embeddings are trained on a large corpus and incorporate extensive knowledge. We demonstrate on three benchmark datasets and two tasks, that BOWL representation shows significant advantages in terms of representation accuracy and efficiency.
- Published
- 2016
18. Reduced mitochondrial size in hippocampus and psychiatric behavioral changes in the mutant mice with homologous mutation of Timm8a1-I23fs49X
- Author
-
Niemtiah Ouattara, Zirui Chen, Yihua Huang, Xia Chen, Pingping Song, Zhongju Xiao, Qi Li, Yuqing Guan, Ziang Li, Yawei Jiang, Kaibiao Xu, Suyue Pan, and Yafang Hu
- Subjects
deafness-dystonia-optic neuronopathy (DDON) syndrome ,DDP1 ,TIMM8A ,MTFP1 ,mitochondrial fission ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
BackgroundDeafness-dystonia-optic neuronopathy (DDON) syndrome, a condition that predominantly affects males, is caused by mutations in translocase of mitochondrial inner membrane 8A (TIMM8A)/deafness dystonia protein 1 (DDP1) gene and characterized by progressive deafness coupled with other neurological abnormalities. In a previous study, we demonstrated the phenotype of male mice carrying the hemizygous mutation of Timm8a1-I23fs49X. In a follow-up to that study, this study aimed to observe the behavioral changes in the female mutant (MUT) mice with homologous mutation of Timm8a1 and to elucidate the underlying mechanism for the behavioral changes.Materials and methodsHistological analysis, transmission electron microscopy (EM), Western blotting, hearing measurement by auditory brainstem response (ABR), and behavioral observation were compared between the MUT mice and wild-type (WT) littermates.ResultsThe weight of the female MUT mice was less than that of the WT mice. Among MUT mice, both male and female mice showed hearing impairment, anxiety-like behavior by the elevated plus maze test, and cognitive deficit by the Morris water maze test. Furthermore, the female MUT mice exhibited coordination problems in the balance beam test. Although the general neuronal loss was not found in the hippocampus of the MUT genotype, EM assessment indicated that the mitochondrial size showing as aspect ratio and form factor in the hippocampus of the MUT strain was significantly reduced compared to that in the WT genotype. More importantly, this phenomenon was correlated with the upregulation of translation of mitochondrial fission process protein 1(Mtfp1)/mitochondrial 18 kDa protein (Mtp18), a key fission factor that is a positive regulator of mitochondrial fission and mitochondrial size. Interestingly, significant reductions in the size of the uterus and ovaries were noted in the female MUT mice, which contributed to significantly lower fertility in the MUT mice.ConclusionTogether, a homologous mutation in the Timm8a1 gene caused the hearing impairment and psychiatric behavioral changes in the MUT mice; the latter phenotype might be related to a reduction in mitochondrial size regulated by MTP18.
- Published
- 2022
- Full Text
- View/download PDF
19. Recent Advancements in Photocatalysis Coupling by External Physical Fields
- Author
-
Yan Mi, Wenjian Fang, Yawei Jiang, Yang Yang, Yongsheng Liu, and Wenfeng Shangguan
- Subjects
photocatalysis ,assisted external physical fields ,coupling effects ,charge separation ,Chemical technology ,TP1-1185 ,Chemistry ,QD1-999 - Abstract
Photocatalysis is one of the most promising green technologies to utilize solar energy for clean energy achievement and environmental governance, such as artificial photosynthesis, water splitting, pollutants degradation, etc. Despite decades of research, the performance of photocatalysis still falls far short of the requirement of 5% solar energy conversion efficiency. Combining photocatalysis with the other physical fields has been proven to be an efficient way around this barrier which can improve the performance of photocatalysis remarkably. This review will focus on the recent advances in photocatalysis coupling by external physical fields, including Thermal-coupled photocatalysis (TCP), Mechanical-coupled photocatalysis (MCP), and Electromagnetism-coupled photocatalysis (ECP). In this paper, coupling mechanisms, materials, and applications of external physical fields are reviewed. Specifically, the promotive effect on photocatalytic activity by the external fields is highlighted. This review will provide a detailed and specific reference for photocatalysis coupling by external physical fields in a deep-going way.
- Published
- 2022
- Full Text
- View/download PDF
20. Antimicrobial Mechanism of Antimicrobial Peptide from Paenibacillus ehimensis against Penicillium expansum Spores
- Author
-
WANG Zhixin, LIU Dandan, JIA Ziwei, HUANG Yuqing, NING Yawei, JIA Yingmin
- Subjects
paenibacillus ehimensis ,antimicrobial peptide ,penicillium expansum ,spore ,antimicrobial mechanism ,Food processing and manufacture ,TP368-456 - Abstract
Penicillium expansum, a common spoilage organism in postharvest fruits, can cause fruit decay and deterioration and endanger human health. It is of great significance to investigate the antimicrobial mechanism of the antimicrobial peptide from Paenibacillus ehimensis on P. expansum spores. The antimicrobial activity of the antimicrobial peptide against P. expansum spores was determined by using the two-fold dilution method as well as measuring the time-killing curve. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to evaluate the effect of the antimicrobial peptide on the ultrastructure of P. expansum spores. The effects of the antimicrobial peptide on the cell membrane and reactive oxygen species (ROS) accumulation of P. expansum were analyzed by fluorescence probes. The results showed that the minimum inhibitory concentration (MIC) of the antimicrobial peptide against P. expansum spores was 3.5 AU/mL. The spore germination rate was significantly decreased by 28.30%, 84.57% and 100% by the antimicrobial peptide at concentrations of 0.5 MIC, 1 MIC and 2 MIC compared with the blank control (P < 0.05). After treatment with the antimicrobial peptide, the spores appeared seriously sunken, the intracellular contents were leaked out, and the morphology and structure were changed. The antimicrobial peptide damaged the cell wall of P. expansum, resulting in the leakage of alkaline phosphatase. The antimicrobial peptide depolarized the cell membrane potential in a dose-dependent manner, and increased the cell membrane permeability, leading to K+ leakage. The fluidity of the cell membrane was increased, which in turn resulted in a significant decrease in DPH fluorescence intensity (P < 0.05). The integrity of the cell membrane was damaged by the antimicrobial peptide, so the fluorescence intensity of SYTOX-Green and the contamination rate of PI were increased. Moreover, the antimicrobial peptide at 1 MIC and 2 MIC increased the fluorescence intensity of DCFH-DA significantly (P < 0.05) and resulted in ROS accumulation, which affected the physiology and metabolism of P. expansum spores. This study indicated that the target sites of the antimicrobial peptide against P. expansum spores were mainly the cell membrane and ROS metabolism.
- Published
- 2023
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.