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4. Sex dependence of postoperative pulmonary complications – A post hoc unmatched and matched analysis of LAS VEGAS

Author

Kroell, Wolfgang, Metzler, Helfried, Struber, Gerd, Wegscheider, Thomas, Gombotz, Hans, Hiesmayr, Michael, Schmid, Werner, Urbanek, Bernhard, Kahn, David, Momeni, Mona, Pospiech, Audrey, Lois, Fernande, Forget, Patrice, Grosu, Irina, Poelaert, Jan, van Mossevelde, Veerle, van Malderen, Marie-Claire, Dylst, Dimitri, van Melkebeek, Jeroen, Beran, Maud, de Hert, Stefan, De Baerdemaeker, Luc, Heyse, Bjorn, Van Limmen, Jurgen, Wyffels, Piet, Jacobs, Tom, Roels, Nathalie, De Bruyne, Ann, van de Velde, Stijn, Leva, Brigitte, Damster, Sandrine, Plichon, Benoit, Juros-Zovko, Marina, Djonoviċ-Omanoviċ, Dejana, Pernar, Selma, Zunic, Josip, Miskovic, Petar, Zilic, Antonio, Kvolik, Slavica, Ivic, Dubravka, Azenic-Venzera, Darija, Skiljic, Sonja, Vinkovic, Hrvoje, Oputric, Ivana, Juricic, Kazimir, Frkovic, Vedran, Kopic, Jasminka, Mirkovic, Ivan, Karanovic, Nenad, Carev, Mladen, Dropulic, Natasa, Saric, Jadranka Pavicic, Erceg, Gorjana, Dvorscak, Matea Bogdanovic, Mazul-Sunko, Branka, Pavicic, Anna Marija, Goranovic, Tanja, Maldini, Branka, Radocaj, Tomislav, Gavranovic, Zeljka, Mladic-Batinica, Inga, Sehovic, Mirna, Stourac, Petr, Harazim, Hana, Smekalova, Olga, Kosinova, Martina, Kolacek, Tomas, Hudacek, Kamil, Drab, Michal, Brujevic, Jan, Vitkova, Katerina, Jirmanova, Katerina, Volfova, Ivana, Dzurnakova, Paula, Liskova, Katarina, Dudas, Radovan, Filipsky, Radek, el Kafrawy, Samir, Abdelwahab, Hisham Hosny, Metwally, Tarek, Abdel-Razek, Ahmed, El-Shaarawy, Ahmed Mostafa, Hasan, Wael Fathy, Ahmed, Ahmed Gouda, Yassin, Hany, Magdy, Mohamed, Abdelhady, Mahdy, Mahran, Mohamed, Herodes, Eiko, Kivik, Peeter, Oganjan, Juri, Aun, Annika, Sormus, Alar, Sarapuu, Kaili, Mall, Merilin, Karjagin, Juri, Futier, Emmanuel, Petit, Antoine, Gerard, Adeline, Marret, Emmanuel, Solier, Marc, Jaber, Samir, Prades, Albert, Krassler, Jens, Merzky, Simone, de Abreu, Marcel Gama, Uhlig, Christopher, Kiss, Thomas, Bundy, Anette, Bluth, Thomas, Gueldner, Andreas, Spieth, Peter, Scharffenberg, Martin, Thiem, Denny Tran, Koch, Thea, Treschan, Tanja, Schaefer, Maximilian, Bastin, Bea, Geib, Johann, Weiss, Martin, Kienbaum, Peter, Pannen, Benedikt, Gottschalk, Andre, Konrad, Mirja, Westerheide, Diana, Schwerdtfeger, Ben, Wrigge, Hermann, Simon, Philipp, Reske, Andreas, Nestler, Christian, Valsamidis, Dimitrios, Stroumpoulis, Konstantinos, Antholopoulos, Georgios, Andreou, Antonis, Karapanos, Dimitris, Theodoraki, Kassiani, Gkiokas, Georgios, Tasoulis, Marios-Konstantinos, Sidiropoulou, Tatiana, Zafeiropoulou, Foteini, Florou, Panagiota, Pandazi, Aggeliki, Tsaousi, Georgia, Nouris, Christos, Pourzitaki, Chryssa, Bystritski, Dmitri, Pizov, Reuven, Eden, Arieh, Pesce, Caterina Valeria, Campanile, Annamaria, Marrella, Antonella, Grasso, Salvatore, De Michele, Michele, Bona, Francesco, Giacoletto, Gianmarco, Sardo, Elena, Sottosanti, Luigi Giancarlo Vicari, Solca, Maurizio, Volta, Carlo Alberto, Spadaro, Savino, Verri, Marco, Ragazzi, Riccardo, Zoppellari, Roberto, Cinnella, Gilda, Raimondo, Pasquale, La Bella, Daniela, Mirabella, Lucia, D'antini, Davide, Pelosi, Paolo, Molin, Alexandre, Brunetti, Iole, Gratarola, Angelo, Pellerano, Giulia, Sileo, Rosanna, Pezzatto, Stefano, Montagnani, Luca, Pasin, Laura, Landoni, Giovanni, Zangrillo, Alberto, Beretta, Luigi, Di Parma, Ambra Licia, Tarzia, Valentina, Dossi, Roberto, Sassone, Marta Eugenia, Sances, Daniele, Tredici, Stefano, Spano, Gianluca, Castellani, Gianluca, Delunas, Luigi, Peradze, Sopio, Venturino, Marco, Arpino, Ines, Sher, Sara, Tommasino, Concezione, Rapido, Francesca, Morelli, Paola, Vargas, Maria, Servillo, Giuseppe, Cortegiani, Andrea, Raineri, Santi Maurizio, Montalto, Francesca, Russotto, Vincenzo, Giarratano, Antonino, Baciarello, Marco, Generali, Michela, Cerati, Giorgia, Leykin, Yigal, Bressan, Filippo, Bartolini, Vittoria, Zamidei, Lucia, Brazzi, Luca, Liperi, Corrado, Sales, Gabriele, Pistidda, Laura, Severgnini, Paolo, Brugnoni, Elisa, Musella, Giuseppe, Bacuzzi, Alessandro, Muhardri, Dalip, Gecaj-Gashi, Agreta, Sada, Fatos, Bytyqi, Adem, Karbonskiene, Aurika, Aukstakalniene, Ruta, Teberaite, Zivile, Salciute, Erika, Tikuisis, Renatas, Miliauskas, Povilas, Jurate, Sipylaite, Kontrimaviciute, Egle, Tomkute, Gabija, Xuereb, John, Bezzina, Maureen, Borg, Francis Joseph, Hemmes, Sabrine, Schultz, Marcus, Hollmann, Markus, Wiersma, Irene, Binnekade, Jan, Bos, Lieuwe, Nijbroek, Sunny, Boer, Christa, Duvekot, Anne, ’t Veld, Bas in, Werger, Alice, Dennesen, Paul, Severijns, Charlotte, De Jong, Jasper, Hering, Jens, van Beek, Rienk, Ivars, Stefan, Jammer, Ib, Breidablik, Alena, Hodt, Katharina Skirstad, Fjellanger, Frode, Avalos, Manuel Vico, Mellin-Olsen, Jannicke, Andersson, Elisabeth, Shafi-Kabiri, Amir, Molina, Ruby, Wutai, Stanley, Morais, Erick, Tareco, Glória, Ferreira, Daniel, Amaral, Joana, de Lurdes Goncalves Castro, Maria, Cadilha, Susana, Appleton, Sofia, Parente, Suzana, Correia, Mariana, Martins, Diogo, Monteirosa, Angela, Ricardo, Ana, Rodrigues, Sara, Horhota, Lucian, Grintescu, Ioana Marina, Mirea, Liliana, Grintescu, Ioana Cristina, Corneci, Dan, Negoita, Silvius, Dutu, Madalina, Garotescu, Ioana Popescu, Filipescu, Daniela, Prodan, Alexandru Bogdan, Droc, Gabriela, Fota, Ruxandra, Popescu, Mihai, Tomescu, Dana, Petcu, Ana Maria, Tudoroiu, Marian Irinel, Moise, Alida, Guran, Catalin-Traian, Gherghina, Iorel, Costea, Dan, Cindea, Iulia, Copotoiu, Sanda-Maria, Copotoiu, Ruxandra, Barsan, Victoria, Tolcser, Zsolt, Riciu, Magda, Moldovan, Septimiu Gheorghe, Veres, Mihaly, Gritsan, Alexey, Kapkan, Tatyana, Gritsan, Galina, Korolkov, Oleg, Kulikov, Alexander, Lubnin, Andrey, Ovezov, Alexey, Prokoshev, Pavel, Lugovoy, Alexander, Anipchenko, Natalia, Babayants, Andrey, Komissarova, Irina, Zalina, Karginova, Likhvantsev, Valery, Fedorov, Sergei, Lazukic, Aleksandra, Pejakovic, Jasmina, Mihajlovic, Dunja, Kusnierikova, Zuzana, Zelinkova, Maria, Bruncakova, Katarina, Polakovicova, Lenka, Sobona, Villiam, Novak-Supe, Barbka, Pekle-Golez, Ana, Jovanov, Miroljub, Strazisar, Branka, Markovic-Bozic, Jasmina, Novak-Jankovic, Vesna, Voje, Minca, Grynyuk, Andriy, Kostadinov, Ivan, Spindler-Vesel, Alenka, Moral, Victoria, Unzueta, Mari Carmen, Puigbo, Carlos, Fava, Josep, Canet, Jaume, Moret, Enrique, Nunez, Mónica Rodriguez, Sendra, Mar, Brunelli, Andrea, Rodenas, Frederic, Monedero, Pablo, Martinezv, Francisco Hidalgo, Temino, Maria Jose Yepes, Simon, Antonio Martínez, de Abajo Larriba, Ana, Lisi, Alberto, Perez, Gisela, Martinez, Raquel, Granell, Manuel, Vivo, Jose Tatay, Ruiz, Cristina Saiz, de Andrés Ibañez, Jose Antonio, Pastor, Ernesto, Soro, Marina, Ferrando, Carlos, Defez, Mario, Alvares-Santullano, Cesar Aldecoa, Perez, Rocio, Rico, Jesus, Jawad, Monir, Saeed, Yousif, Gillberg, Lars, Hedenstierma, Göran, Bengisun, Zuleyha Kazak, Kazbek, Baturay Kansu, Coskunfirat, Nesil, Boztug, Neval, Sanli, Suat, Yilmaz, Murat, Hadimioglu, Necmiye, Senturk, Nuzhet Mert, Camci, Emre, Kucukgoncu, Semra, Sungur, Zerrin, Sivrikoz, Nukhet, Ozgen, Serpil Ustalar, Toraman, Fevzi, Selvi, Onur, Senturk, Ozgur, Yildiz, Mine, Kuvaki, Bahar, Gunenc, Ferim, Kucukguclu, Semih, Ozbilgin, Şule, Maral, Jale, Canli, Seyda, Arun, Oguzhan, Saltali, Ali, Aydogan, Eyup, Akgun, Fatma Nur, Sanlikarip, Ceren, Karaman, Fatma Mine, Mazur, Andriy, Vorotyntsev, Sergiy, Rousseau, Guy, Barrett, Colin, Stancombe, Lucia, Shelley, Ben, Scholes, Helen, Limb, James, Rafi, Amir, Wayman, Lisa, Deane, Jill, Rogerson, David, Williams, John, Yates, Susan, Rogers, Elaine, Pulletz, Mark, Moreton, Sarah, Jones, Stephanie, Venkatesh, Suresh, Burton, Maudrian, Brown, Lucy, Goodall, Cait, Rucklidge, Matthew, Fuller, Debbie, Nadolski, Maria, Kusre, Sandeep, Lundberg, Michael, Everett, Lynn, Nutt, Helen, Zuleika, Maka, Carvalho, Peter, Clements, Deborah, Creagh-Brown, Ben, Watt, Philip, Raymode, Parizade, Pearse, Rupert, Mohr, Otto, Raj, Ashok, Creary, Thais, Chishti, Ahmed, Bell, Andrea, Higham, Charley, Cain, Alistair, Gibb, Sarah, Mowat, Stephen, Franklin, Danielle, West, Claire, Minto, Gary, Boyd, Nicholas, Mills, Gary, Calton, Emily, Walker, Rachel, Mackenzie, Felicity, Ellison, Branwen, Roberts, Helen, Chikungwa, Moses, Jackson, Clare, Donovan, Andrew, Foot, Jayne, Homan, Elizabeth, Montgomery, Jane, Portch, David, Mercer, Pauline, Palmer, Janet, Paddle, Jonathan, Fouracres, Anna, Datson, Amanda, Andrew, Alyson, Welch, Leanne, Rose, Alastair, Varma, Sandeep, Simeson, Karen, Rambhatla, Mrutyunjaya, Susarla, Jaysimha, Marri, Sudhakar, Kodaganallur, Krishnan, Das, Ashok, Algarsamy, Shivarajan, Colley, Julie, Davies, Simon, Szewczyk, Margaret, Smith, Thomas, Fernandez-Bustamante, Ana, Luzier, Elizabeth, Almagro, Angela, Melo, Marcos Vidal, Fernando, Luiz, Sulemanji, Demet, Sprung, Juraj, Weingarten, Toby, Kor, Daryl, Scavonetto, Federica, Tze, Yeo, Vermeulen, Tom D., Hol, Liselotte, Swart, Pien, Mills, Gary H., Putensen, Christian, Serpa Neto, Ary, Vidal Melo, Marcos F., Hollmann, Markus W., Gama de Abreu, Marcelo, Schultz, Marcus J., Hemmes, Sabrine N., and van Meenen, David M.

Published
2024
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5. Wind Power

Author

Yates, Susan, Bigelow, Philip, Fiore, Mariantonietta, Section editor, and Maggino, Filomena, editor

Published
2023
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10. The cultural adaptation of iSupport program: Experiences from Australia, Brazil, Indonesia, New Zealand and Qatar

Author

Nguyen, Tuan Anh, primary, McCalmont, Danielle, additional, Kosowicz, Leona, additional, Sinclair, Ron, additional, Sani, Tara P, additional, Cullum, Sarah J, additional, Turana, Yuda, additional, Oliveira, Déborah, additional, Hamad, Hanadi Al, additional, Chandran, Mani, additional, Xiao, Lily Dongxia, additional, Brodaty, Henry, additional, Andrade, Andre, additional, Esterman, Adrian, additional, Kurrle, Susan, additional, Crotty, Maria, additional, Schofield, Penelope, additional, Bhar, Sunil, additional, Wickramasinghe, Nilmini, additional, Dang, Thu Ha, additional, Roughead, Elizabeth E, additional, Tran, Kham, additional, Kristian, Kevin, additional, Handajani, Yvonne S, additional, Cheung, Gary, additional, Peri, Kathy, additional, Yates, Susan, additional, Whaanga, Hēmi, additional, Thang, Pham, additional, Nguyen, Binh Thanh, additional, Nguyen, Trung Anh, additional, Trong, Hung Nguyen, additional, Vu, Huyen Thi Thanh, additional, Nguyen, Binh Thi Thanh, additional, Nguyen, Anh Ngoc, additional, Nguyen, Anh Thi Phuong, additional, Nguyen, Thu Thi Hoai, additional, Nguyen, Phong Quy, additional, Nguyen, Hung Ngoc, additional, Nguyen, Thanh Xuan, additional, Van Ho, Hung, additional, Le, Ngoc Thi, additional, Ferreira, Camila Rafael, additional, Monteiro, Diana Quirino, additional, Ottaviani, Ana Carolina, additional, Cardoso, Anabel Machado, additional, Barbosa, Gustavo Carrijo, additional, Correa, Larissa, additional, Rocha, Luana Aparecida, additional, Alves, Ludmyla Caroline de Souza, additional, Maciel, Luiza Barros, additional, Barham, Elizabeth Joan, additional, Orlandi, Fabiana de Souza, additional, de Cruz, Keila Cristianne Trindade, additional, Pavarini, Sofia Cristina Iost, additional, Gratão, Aline Cristina Martins, additional, Manikoth, Pravija Talapan, additional, Badarudeen, Irshad, additional, and Brijnath, Bianca, additional

Published
2023
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12. Living with Dementia in Aotearoa (LiDiA): A Feasibility Study for a Dementia Prevalence Study in Māori and Non-Māori Living in New Zealand.

Author

Martinez-Ruiz, Adrian, Yates, Susan, Cheung, Gary, Cullum, Sarah, Dudley, Makarena, Krishnamurthi, Rita, Fa'alau, Fuafiva, Kerse, Ngaire, Roberts, Mary, Taufa, Seini, and Rivera Rodriguez, Claudia

Subjects
PATIENT selection, POPULATION-based case control, RESEARCH funding, PILOT projects, INTERVIEWING, QUESTIONNAIRES, HUMAN research subjects, DISEASE prevalence, DESCRIPTIVE statistics, MAORI (New Zealand people), RESEARCH methodology, DEMENTIA, PSYCHOSOCIAL factors, LABOR supply
Abstract

Introduction: Recent estimations have projected a threefold increase in dementia prevalence in Aotearoa New Zealand (NZ) by 2050, particularly in Maori and Pacific peoples. However, to date, there are no national data on dementia prevalence, and overseas data are used to estimate the NZ dementia statistics. The aim of this feasibility study was to prepare the groundwork for the first full-scale NZ dementia prevalence study that is representative of Māori, European, Pacific and Asian peoples living in NZ. Methods: The main feasibility issues were: (i) Sampling to ensure adequate community representation from the included ethnic groups, (ii) Preparing a workforce to conduct the fieldwork and developing quality control, (iii) Raising awareness of the study in the communities (iv) Maximizing recruitment by door-knocking, (v) Retaining those we have recruited to the study and (vi) Acceptability of study recruitment and assessment using adapted versions of the 10/66 dementia protocol in different ethnic groups living in South Auckland. Results: We found that a probability sampling strategy using NZ Census data was reasonably accurate and all ethnic groups were sampled effectively. We demonstrated that we were able to train up a multi-ethnic workforce consisting of lay interviewers who were able to administer the 10/66 dementia protocol in community settings. The response rate (224/297, 75.5%) at the door-knocking stage was good but attrition at subsequent stages was high and only 75/297 (25.2%) received the full interview. Conclusions: Our study showed that it would be feasible to conduct a population-based dementia prevalence study using the 10/66 dementia protocol in Māori, European and Asian communities living in NZ, utilizing a qualified, skilled research team representative of the families participating in the study. The study has demonstrated that for recruitment and interviewing in Pacific communities a different but culturally appropriate approach is required. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Living with Dementia in Aotearoa (LiDiA): A Feasibility Study for a Dementia Prevalence Study in Māori and Non-Māori Living in New Zealand

Author

Martinez-Ruiz, Adrian, primary, Yates, Susan, additional, Cheung, Gary, additional, Cullum, Sarah, additional, Dudley, Makarena, additional, Krishnamurthi, Rita, additional, Fa’alau, Fuafiva, additional, Kerse, Ngaire, additional, Roberts, Mary, additional, Taufa, Seini, additional, and Rivera Rodriguez, Claudia, additional

Published
2023
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21. Start Out: Building Healthcare Careers for Minority Teenagers.

Author

Yates, Susan Hunter, Bline, Kerri, and Bird, Chelsea

Abstract

To interest multicultural, bilingual teenagers in nursing careers, an 8-week culturally focused summer program integrated life planning, mentorship, nursing assistant training, and college application assistance while providing stipends and scholarship opportunities. Twenty-four economically disadvantaged teenagers completed the program and passed the certified nursing assistant examination. (SK)

Published
2003

22. The HOPA Gene Dodecamer Duplication Is Not a Significant Etiological Factor in Autism.

Author

Michaelis, Ron C., Copeland-Yates, Susan A., and Sossey-Alaoui, Khalid

Abstract

A study of 202 patients with autism found the incidence of a dodecamer duplication in the HOPA gene was not significantly different between patients and controls. Three female patients inherited the duplication from nonautistic fathers. Also, there was no systematic skewing of X inactivation in female patients with the duplication. (Contains references.) (Author/CR)

Published
2000

31. Actin polymerization is controlled by residue size at position 204

Author

Yates, Susan P., Loncar, Ana, and Dawson, John F.

Subjects
Polymerization -- Analysis -- Physiological aspects -- Research -- Health aspects, Adenosine triphosphatase -- Research -- Physiological aspects -- Analysis -- Health aspects, Muscle proteins -- Physiological aspects -- Research -- Analysis -- Health aspects, Actin -- Health aspects -- Analysis -- Research -- Physiological aspects, Biological sciences, Physiological aspects, Analysis, Research, Health aspects
Abstract

Previous work has shown that purified double mutant A204C/C374A yeast actin is polymerization-deficient in vitro under physiological concentrations. To understand the importance of the 204 residue in subdomain 4, a series of actin proteins with a single mutation at this position were created with Cys-374 retained. Only yeast expressing A204G-, A204S-, or A204C-actin were viable. The A204G and A204S strains were sensitive to cold temperature and hyperosmolarity, whereas the A204C strain showed more profound effects on growth under these conditions. Cells expressing A204Cactin exhibited anomalies previously observed for A204C/C374A actin, including abnormal actin structures. A204G- and A204S-actin proteins had 12- and 13-fold increased critical concentrations, respectively, relative to wild-type. Only at very high concentrations could A204C actin polymerize when ATP was bound; when hydrolyzed, the ADP-containing A204C filaments depolymerized, demonstrating a profound difference in critical concentration between ATP and ADP states with A204C actin. A correlation between size of the residue substituted at position 204 and energy minimization of actin filament models was observed. We propose that the region surrounding residue 204 is involved in interactions that change depending on the phosphorylation state of the bound nucleotide that might reflect different conformations of F-actin subunits. Key words: actin polymerization, mutagenesis, critical concentration, nucleotide. Des travaux anterieurs ont montre que le double mutant purifie A204C/C374A de l'actine de levure possede un defaut de polymerisation in vitro sous des conditions physiologiques. Afin de comprendre l'importance du residu 204 du sous-domaine 4, une serie de proteines comportant une mutation ponctuelle a cette position ont ete produites, en conservant la Cys-374. Seules les levures exprimant les formes A204G, A204S ou A204C de l'actine etaient viables. Les souches A204G et A204S etaient sensibles au froid et a l'hyperosmolarite, alors que la souche A204C montrait des problemes de croissance plus prononces sous ces conditions. Les cellules exprimant l'actine A204C montraient des anomalies deja observe es chez les cellules exprimant la forme A204C/C374A, incluant des structures anormales d'actine. Les proteines A204G et A204S possedaient des concentrations critiques respectivement 12 et 13 fois superieures, relativement au type sauvage. L'actine A204C ne polymerisait qu'a tres haute concentration lorsque l'ATP etait liee; apres hydrolyse, les filaments d'actine A204C contenant l'ADP depolymerisaient, demontrant l'existence d'une difference importante dans les concentrations critiques des formes liees a l'ATP et a l'ADP de l'actine A204C. Une correlation entre la taille des residus substitues en position 204 et la minimisation d'energie des modeles de filaments d'actine a ete observee. Nous proposons que la region environnant le residu 204 est impliquee dans les interactions qui changent selon l'etat de phosphorylation du nucleotide lie, refletant possiblement differentes conformations des sous-unites d'actine. Mots-cles : polymerisation de l'actine, mutagenese, concentration critique, nucleotide. [Traduit par la Redaction], Introduction Actin is a 42 kDa cytoskeletal protein involved in a plethora of physiological processes. Polymerization into long filaments (F-actin) is a fundamental activity of the actin protein. F-actin can [...]

Published
2009
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33. Living with Dementia in Aotearoa (LiDiA): a cross-sectional feasibility study protocol for a multiethnic dementia prevalence study in Aotearoa/New Zealand

Author

Martinez-Ruiz, Adrian, primary, Yates, Susan, additional, Cheung, Gary, additional, Dudley, Makarena, additional, Krishnamurthi, Rita, additional, Fa’alau, Fuafiva, additional, Roberts, Mary, additional, Taufa, Seini, additional, Fa’alili-Fidow, Jacinta, additional, Rivera-Rodriguez, Claudia, additional, Kautoke, Staverton, additional, Ma’u, Etuini, additional, Kerse, Ngaire, additional, and Cullum, Sarah, additional

Published
2021
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34. Stealth and mimicry by deadly bacterial toxins

Author

Yates, Susan P., JA[cedilla]rgensen, Rene, Andersen, Gregers R., and Merrill, A. Rod

Subjects
Antitoxins, Protein biosynthesis, Bacterial proteins, Biological sciences, Chemistry
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.tibs.2005.12.007 Byline: Susan P. Yates (a), Rene JA[cedilla]rgensen (a), Gregers R. Andersen (b), A. Rod Merrill (a) Abstract: Diphtheria toxin and exotoxin A are well-characterized members of the ADP-ribosyltransferase toxin family that function as virulence factors in the pathogenic bacteria Corynebacterium diphtheriae and Pseudomonas aeruginosa. Recent high-resolution structural data of the Michaelis (enzyme-substrate) complex of the P. aeruginosa toxin with an NAD.sup.+ analog and eukaryotic elongation factor 2 (eEF2) have provided insights into the mechanism of inactivation of protein synthesis caused by these protein factors. In addition, rigorous steady-state and stopped-flow kinetic analyses of the toxin-catalyzed reaction, in combination with inhibitor studies, have resulted in a quantum leap in our understanding of the mechanistic details of this deadly enzyme mechanism. It is now apparent that these toxins use stealth and molecular mimicry in unleashing their toxic strategy in the infected host eukaryotic cell. Author Affiliation: (a) Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada (b) Centre for Structural Biology, Department of Molecular Biology, University of Aarhus, Gustav Wieds Vej 10C, DK-8000, Denmark

Published
2006

35. Predictors of Aged Residential Care Placement in Patients Newly Diagnosed with Dementia at a New Zealand Memory Service

Author

Cullum, Sarah, primary, Varghese, Chris, additional, Yates, Susan, additional, Kalatau, Lolomani, additional, Appleton, Jasmine, additional, Knell, Rebecca, additional, Prigent, Camille, additional, Christie, Madeline, additional, Appleton, Kerry, additional, Hadfield, Laura, additional, Liu, Bonnie, additional, Rajay, Aakash, additional, Yeom, Brian, additional, Oulaghan, Bede, additional, Whittington, Rosie, additional, and Cheung, Gary, additional

Published
2021
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36. Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry

Author

Jorgensen, Rene, Merrill, A. Rod, Yates, Susan P., Marquez, Victor E., Schwan, Adrian L., Boesen, Thomas, and Andersen, Gregers R.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): René Jørgensen [1, 5]; A. Rod Merrill (corresponding author) [2, 5]; Susan P. Yates [2]; Victor E. Marquez [4]; Adrian L. Schwan [3]; Thomas Boesen [1]; Gregers R. Andersen [...]

Published
2005
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37. Diagnostic accuracy of the 10/66 dementia assessment tool in Māori, Fijian‐Indian, Samoan and Tongan elders with memory problems living in South Auckland, New Zealand

Author

Martinez‐Ruiz, Adrian, primary, Yates, Susan, additional, Cheung, Gary, additional, Dudley, Makarena Diana, additional, Krishnamurthi, Rita, additional, Fa'alau, Fuafiva, additional, Roberts, Mary, additional, Taufa, Seini, additional, Fa'alili, Jacinta, additional, Kerse, Ngaire, additional, and Cullum, Sarah, additional

Published
2020
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39. Big data and dementia in New Zealand

Author

Yates, Susan, primary, Rodriguez, Claudia Rivera, additional, Martinez‐Ruiz, Adrian, additional, Coomarasamy, Christin, additional, Whittington, Rosie, additional, Krishnamurthi, Rita, additional, Cheung, Gary, additional, Kerse, Ngaire, additional, and Cullum, Sarah, additional

Published
2020
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40. Somali conceptions and expectations concerning mental health: some guidelines for mental health professionals

Author

Guerin, Bernard, Guerin, Pauline, Diiriye, Roda Omar, and Yates, Susan

Subjects
Refugees, Somali -- Health aspects, Public health, Psychiatric services, Mental health
Abstract

The Somali population in New Zealand is a rapidly growing one that should be of interest to mental health professionals due to their experience of resettlement stressors and the refugee [...]

Published
2004

42. Predictors of mortality in Māori, Pacific Island, and European patients diagnosed with dementia at a New Zealand Memory Service

Author

Cullum, Sarah, primary, Varghese, Chris, additional, Coomarasamy, Christin, additional, Whittington, Rosie, additional, Hadfield, Laura, additional, Rajay, Aakash, additional, Yeom, Brian, additional, Liu, Bonnie, additional, Christie, Madeline, additional, Appleton, Kerry, additional, Yates, Susan, additional, and Cheung, Gary, additional

Published
2020
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46. Do Māori and Pacific Peoples Living with Dementia in New Zealand Receive Equitable Long-Term Care Compared with New Zealand Europeans?

Author

MA'U, ETUINI, SAEED, FADY, YATES, SUSAN, OULAGHAN, BEDE, WHITTINGTON, ROSIE, COOMARASAMY, CHRISTIN, CHEUNG, GARY, and CULLUM, SARAH

Subjects
EUROPEANS, DEMENTIA patients, PACIFIC Islanders, RESEARCH funding, HEALTH equity, SOCIODEMOGRAPHIC factors, LONG-term health care
Abstract

Context: Compared to Europeans, Māori and Pacific peoples living with dementia in the Counties Manukau District Health Board region are three times less likely to use Aged Residential Care (ARC). Objectives: The aim of this study was to investigate whether reduced ARC utilisation by Māori and Pacific peoples living with dementia is equitably compensated by an increase in Home Based Support Service (HBSS). Methods: Routinely collected sociodemographic and clinical data for people diagnosed with dementia at an NZ memory service (2013-2019) were linked with administrative ARC and HBSS invoicing data. Two-part models were used to estimate adjusted costs of HBSS utilisation or ARC placement. Findings: six hundred fifty-seven people of European, Māori and Pacific ethnicity were included in the analysis. Compared to Europeans, both unadjusted and adjusted ARC costs per person-year were significantly lower for both Māori (-NZD$3580, 95%CI: -$6890, -$140) and Pacific peoples (-NZD$3110, 95%CI: -$5590, -$540) but HBSS cost per person-year was only higher for Pacific peoples (+NZD$640, 95%CI: $100, $1180) and not Māori (+NZD$180, 95%CI: -$470, $840). There was no significant difference in the combined HBSS and ARC cost per person-year for Māori (-NZD3460, 95%CI -7200, 280) or Pacific peoples (-NZD2490 95%CI -5090, 110). Conclusions: Lower ARC utilisation amongst Māori and Pacific peoples living with dementia does not translate to an equitable increase in HBSS spend. The difference is likely to be compensated by care provided by unpaid family carers. Addressing the wider determinants of long-term care use in these populations and providing alternative culturally appropriate services must be prioritised to address this inequity in allocation of public sector resources. [ABSTRACT FROM AUTHOR]

Published
2022
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