Search

PURPOSE: To evaluate the frequency of abdominal computed tomography (CT) findings in patients with coronavirus disease-2019 (COVID-19) and interrogate the relationship between abdominal CT findings and patient demographic features, clinical findings, and laboratory test results as well as the CT atherosclerosis score in the abdominal aorta. METHODS: This study was designed as a multicenter retrospective study. The abdominal CT findings of 1.181 patients with positive abdominal symptoms from 26 tertiary medical centers with a positive polymerase chain-reaction test for severe acute respiratory syndrome coronavirus 2 were reviewed. The frequency of ischemic and non-ischemic CT findings as well as the association between CT findings, clinical features, and abdominal aortic calcific atherosclerosis score (AA-CAS) were recorded. RESULTS: Ischemic and non-ischemic abdominal CT findings were detected in 240 (20.3%) and 328 (27.7%) patients, respectively. In 147 patients (12.4%), intra-abdominal malignancy was present. The most frequent ischemic abdominal CT findings were bowel wall thickening (n = 120; 10.2%) and perivascular infiltration (n = 40; 3.4%). As for non-ischemic findings, colitis (n = 91; 7.7%) and small bowel inflammation (n = 73; 6.2%) constituted the most frequent disease processes. The duration of hospital stay was found to be higher in patients with abdominal CT findings than in patients without any positive findings (13.8 ± 13 vs. 10.4 ± 12.8 days, P < 0.001). The frequency of abdominal CT findings was significantly higher in patients who did not survive the infection than in patients who were discharged after recovery (41.7% vs. 27.4%, P < 0.001). Increased AA-CAS was found to be associated with a higher risk of ischemic conditions in abdominal CT examinations. CONCLUSION: Abdominal symptoms in patients with COVID-19 are usually associated with positive CT findings. The presence of ischemic findings on CT correlates with poor COVID-19 outcomes. A high AA-CAS is associated with abdominal ischemic findings in patients with COVID-19.

Objectives Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure. We investigated the optic nerve, Meckel’s cavity, internal carotid artery (ICA) and pituitary findings of IIH by Cranial Magnetic Resonance Imaging (MRI). Methods Cranial MRI images of 35 adult patients with IIH and 35 adult subjects with normal cranial MRI results (control) were evaluated. Optic nerve diameter (OND), optic nerve sheat diameter (ONSD), OND/ONSD ratio, ON tortuosity, ON protrusion, posterior scleral flattening, ICA transverse diameter, CSF distance in Meckel’s cavity and ICA transverse diameter/CSF distance in Meckel’s cavity ratio, and pituitary gland measurements (height and transverse dimension; and Optic chiasm- pituitary gland distance) were measured. Results OND and ONSD of the IIH group were significantly higher than those of the control groups at anterior and posterior measurements (p Conclusion OND/ONSD ratio is different in anterior and posterior measurements. So we recommend measuring OND and ONSD separately in IIH patients to use in the clinical practice. Similarly, optic chiasm-pituitary gland distance is also another point to note for IIH patients on MRI. Our paper adds new approach to IIH in terms of OND/ONSD ratio.

Hypereosinophilic syndrome (HES) is a rare hematological disease that causes organ damage by eosinophil infiltration in the tissue with increased eosinophil production in the bone marrow. HES is a rare but important cause of stroke. Central nervous system involvement findings can be serious and life-threatening. Eosinophil values should be examined as the cause of stroke, and hypereosinophilia should be suspected, especially in young patients with no etiology. Reported herein is a case of a 47-year-old female patient who was followed up with the diagnosis of acute cerebrovascular disease due to idiopathic HES.

…

Amaç: Sağlıklı bireylerde böbrek üstü bezine ait görünen difüzyon katsayısı değerler aralıklarının saptanması amaçlanmıştır.Gereç ve Yöntem: Retrospektif olarak planlanan çalışmamıza, böbrek üstü patolojisi veya endokrin patoloji tanımlamayan 25 sağlıklı erişkin olgu dahil edildi. 1.5 Tesla MRG cihazı ile b 0 ve 800 s/ mm2 değerleri kullanılarak her iki böbrek üstü bezinde ikişer kere ölçüm yapıldı. Elde edilen görünen difüzyon katsayısı değerleri istatistiksel olarak kıyaslandı ve ortalaması elde olundu.Bulgular: Ortalama 21.4 mm2 ROI ile sağ böbrek üstü bezine ait ile elde olunan görünen difüzyon katsayısı ölçüm değerleri sırasıyla 1.33±0.2x10-3 mm2/s ve 1.29±0.3x10-3 mm2/s (ortalama 1.31±0.25x10-3 mm2/s) olarak saptandı. Sol böbreğe ait görünen difüzyon katsayısı ölçümleri ise sırasıyla 1.3±0.2x10-3 ve 1.30±0.2x10-3 mm2/s (ortalama 1.3±0.2x10-3 mm2/s) olarak saptandı. Her iki adrenal için ortalama değer 1.3±0.2x10-3 mm2/s olarak bulundu. Elde olunan her dört ölçüm arasında istatistiksel olarak anlamlı farklılık saptanmadı. Sonuç: Sağlıklı bireylerde mevcut MRG cihazı ve protokollerimizle elde olunan ortalama görünen difüzyon katsayısı değerleri, belirgin yer kaplayıcı lezyon göstermeyen diffüz böbrek üstü bezi patolojilerinin değerlendirmesine ışık tutacağı inancındayız.

Background and aim Carbon monoxide poisoning is a toxicological emergency that causes neurological complications. High serum neurogranin can be detected in acute or chronic conditions where brain tissue is damaged. This study aimed to investigate the diagnostic value of serum neurogranin level and its role in demonstrating neurological damage in patients admitted to the emergency department with carbon monoxide poisoning. Materials and methods The study was conducted prospectively on patients with carbon monoxide poisoning (patient group) and healthy volunteers (control group). Demographic characteristics and serum neurogranin level of all participants and symptoms at admission, neurological examination findings, laboratory results, and Diffusion-Weighted Magnetic Resonance Imaging results of the patient group were recorded. We used an independent sample t-test to compare neurogranin levels and bivariate correlation analysis to compare the relationship between serum neurogranin levels and data belonging to the patient group. Results Sixty eight participants (patient group, n = 36; control group, n = 32) were included in the study. Serum neurogranin level was significantly higher in patients with carbon monoxide poisoning (0.31 ± 0.16 ng/ml) compared to control group (0.22 ± 0.10 ng/ml) (p = 0.015). The mean Glasgow Coma Scale of the patients with carbon monoxide poisoning was 14.59 ± 0.23, and of Diffusion Weighted Magnetic Resonance Imaging results were completely normal in 94.4% (n = 34). There was no correlation between serum neurogranin level and Diffusion Weighted Magnetic Resonance Imaging results (r = −0.011; p = 0.953). Conclusion Serum neurogranin level may be a new diagnostic biomarker in patients admitted to the emergency department with carbon monoxide poisoning. The high serum neurogranin levels detected in patients with normal diffusion-weighted imaging after carbon monoxide poisoning suggest that there is neurological damage in these patients, even if imaging methods cannot detect it.

Mowat–Wilson syndrome (MWS) is an autosomal dominant genetic disorder caused by ZEB2 gene mutations, manifesting with unique facial characteristics, moderate to severe intellectual problems, and congenital malformations as Hirschsprung disease, genital and ophthalmological anomalies, and congenital cardiac anomalies. Herein, a case of 1-year-old boy with isolated agenesis of corpus callosum (IACC) in the prenatal period is presented. He was admitted postnatally with Hirschsprung disease (HSCR), hypertelorism, uplifted earlobes, deeply set eyes, frontal bossing, oval-shaped nasal tip, ‘‘M’’ shaped upper lip, opened mouth and prominent chin, and developmental delay. Hence, MWS was primarily considered and confirmed by the ZEB2 gene mutation analysis. His karyotype was normal. He had a history of having a prenatally terminated brother with similar features. Antenatally detected IACC should prompt a detailed investigation including karyotype and microarray; even if they are normal then whole exome sequencing (WES) should be done.

Background/aim The aim of this study was to compare renal and pancreatic apparent diffusion-coefficient (ADC) values of diabetic patients and control subjects and to examine their potential association with several diabetes-related clinical parameters. Materials and methods A total of 80 sex- and age-matched patients were included in the study. Of them, 40 were patients with type 2 diabetes and 40 were nondiabetic participants. Abdominal diffusion-weighted MRIs of both groups were retrospectively reviewed. Diabetes-related clinical parameters were recorded. Results The difference between the mean ADC values of the patient group and the control group was significant (p = 0.012). It was also found that the mean pancreatic ADC values of diabetic patients and the control group significantly differed (p = 0.02). Besides, there were positive correlations between the mean pancreatic ADC values and age, Hb1Ac level, treatment type, and disease duration (p < 0.05). While eGFR values positively correlated with the mean renal ADC values (p < 0.05), there were negative correlations between such values and age, serum creatinine level, and disease duration (p < 0.05). Conclusion Renal and pancreatic ADC values of diabetic patients could potentially play a role, as markers of renal and pancreatic functions, in clinical decisions in the follow-up of such patients.

WOS:000582143700006 PubMed: 32856885 Background: Considering the critical role of early diagnosis and management of acute ischemic stroke, biomarkers that can reliable assist in the diagnosis are still needed. These biomarkers should rapidly analyze, have high specificity for brain damage, and be available in the emergency settings for early diagnosis and exclusion of other conditions that mimic acute ischemic stroke. Soluble tumor necrosis factor-like weak inducer of apoptosis, a protein involved in the regulation of several biological functions, could be a potential acute ischemic stroke biomarker. Aims: To investigate the diagnostic value of soluble tumor necrosis factor-like weak inducer of apoptosis in patients with acute ischemic stroke and examine the relationship between ischemic area volume determined at diffusion-weighted magnetic resonance imaging and soluble tumor necrosis factor-like weak inducer of apoptosis. Study Design: A prospective, case-control study. Methods: This case-control prospective study included 36 patients with acute ischemic stroke and 36 healthy volunteers. Information on age, sex, presence of chronic disease, neurological examination findings, times of presentation to the emergency department after acute ischemic stroke, soluble tumor necrosis factor-like weak inducer of apoptosis levels, ischemic area volumes at diffusion-weighted magnetic resonance imaging, and 6-month mortality rates after stroke were recorded. The results were analyzed on SPSS 22.0 software (SPSS Inc., Chicago, IL, USA), and p

WOS: 000523403800001 PubMed: 32248444 Objective The incidence of osteoarthritis is gradually increasing in public due to aging and increase in obesity. Various imaging methods are used in the diagnosis of hip osteoarthritis, and plain pelvic radiography is the first preferred imaging method in the diagnosis of hip osteoarthritis. In this study, we aimed to develop a computer-aided diagnosis method that will help physicians for the diagnosis of hip osteoarthritis by interpreting plain pelvic radiographs. Materials and methods In this retrospective study, convolutional neural networks were used and transfer learning was applied with the pre-trained VGG-16 network. Our dataset consisted of 221 normal hip radiographs and 213 hip radiographs with osteoarthritis. In this study, the training of the network was performed using a total of 426 hip osteoarthritis images and a total of 442 normal pelvic images obtained by flipping the raw data set. Results Training results were evaluated with performance metrics such as accuracy, sensitivity, specificity, and precision calculated by using the confusion matrix. We achieved accuracy, sensitivity, specificity and precision results at 90.2%, 97.6%, 83.0%, and 84.7% respectively. Conclusion We achieved promising results with this computer-aided diagnosis method that we tried to develop using convolutional neural networks based on transfer learning. This method can help clinicians for the diagnosis of hip osteoarthritis while interpreting plain pelvic radiographs, also provides assistance for a second objective interpretation. It may also reduce the need for advanced imaging methods in the diagnosis of hip osteoarthritis.

Amaç: Biz bu çalışmada normal veya patolojik apendiksin ileal segmentlerden sonografik olarak ayırtedilebilmesi için gerekli yeni ve objektif kriterler tespit etmeyi amaçladık.Materyal ve Metodlar: Normal ve patolojik apendikslerin, ileumun ikinci ve üçüncü formlarının transvers ultrasonografik kesitleri üzerinde milimetrik olarak uzun çap, kısa çap, ortalama çap, dairesellik indeksi, ve çap indeksi hesaplandı.Bulgular: Dairesellik indeksi, sirkülarite indeksi ve uzun çap, normal veya patolojik apendiksin ileal segmentlerden ayırtedilmesinde yüksek oranda sensitivite ve spesifisite gösterdi.Sonuç: Dairesellik indeksi, sirkülarite indeksi ve uzun çap normal veya patolojik apendiksin ileumdan ultrasonografik olarak ayırtedilmesinde objektif ve etkin kriterlerdir Aim: We aimed to establish the new and objective criteria that can be used for distinguishing the normal or pathological appendix from ileal segments sonographically.Materials and Methods:Long diameter, short diameter, mean diameter, circularity index (CI), and diameter index (DI) in mm on transverse images of normal and pathological appendices, and the others form of the ileum, were calculated. Results:DI, CI, long dimension show high sensitivity and specificity in discrimination of the normal or pathological appendix from ileal segments.Conclusion: DI, CI, and long dimension are effective and objective criteria for distinguishing normal or pathological appendix from ileum sonographically

Amaç: Biz bu çalışmada farklı lokalizasyonlardaki apendiksleri inceleyerek önceki literatürden farklı bir sınıflama yapmayı ve böylece appendiksin sonografik incelemesini kolaylaştırmayı amaçladık.Materyal ve metod: Çalışma bizim departmanımıza pelvik veya batın ultrasonografisi amacı ile başvuran 362 ardışık hasta üzerinde gerçekleştirildi. Normal sonografik apendiks kriterleri maksimum çapı 6 mm olan, komprese olan, kör sonlanan tübüler yapı olarak belirlendi. Appendiksler ultrasonografi ile incelendi ve kaydedildi, referans çizgisi olarak da sağ iliak fossadaki iliak damarlar alındı.Bulgular: Apendiksler yerleşim yerine göre 1-8 sınıfa ayrıldı. Tip 1 iliak damarları geçen (85.5%),tip 2 iliak damarların hemen yanında (2.41%), tip 3 çekumun inferior ve lateralinde (1.93%), tip 4 sağ parakolik olukta (4.34%), tip 5 tamamen retroçekal (1.93%), tip 6 çekumun anteriorunda (1.45%), tip 7 umblikusa uzanan (0.97%) and tip 8 çekal malpozisyonla birlikte subhepatik yerleşim (1.45%).Sonuç: Bu çalışmada literatürde daha önceden tanımlanandan farklı olarak yeni bir sınıflama sistemi ortaya konulmuştur. Normal ve anormal apendikslerin en sık görülen yerleşimi iliak damarları geçen tip 1 olarak izlendi. İkinci en sık görülen yerleşim ise sağ parakolik olukta izlenen tip 4 idi. İki farklı ilginç yerleşim ise umblikusa uzanan tip 7 ile subhepatik alana uzanan tip8 idi Aim:We intended to detect various appendix localisations with a classification system different from those used in previous literature to facilitate the sonographic detection of the appendix.Patients and methods: The study was performed on 362 consecutive patients who applied to our department for abdominal or pelvic US examination to our department. The sonographic criterion used to diagnose a normal appendix was visualization of the full extension of a compressible, blind-ending tubular structure with a maximum transverse diameter of 6 mm. Appendices were evaluated by US and localisations were recorded and classified according to the reference line passing through the iliac vessels in the right iliac fossa.Results: Each appendix was classified as type 1 to 8 according to its location. Type 1 crossed the iliac vessels (85.5%), type 2 was medial to the iliac vessels (2.41%), type 3 was inferior and lateral to the cecum (1.93%), type 4 was in the right paracolic gutter (4.34%), type 5 was completely retrocecal (1.93%), type 6 was in front of the cecum (1.45%), type 7 extended to the umbilicus (0.97%) and type 8 was subhepatic with cecal malposition (1.45%).Conclusion: The study demonstrated a new classification system (types 1-8) different from those described in previous literature. The most common position of the normal and abnormal appendices in our study was crossing the iliac vessels (type 1). The second most common position was the right paracolic gutter (type 4). Two interesting localisations extended to the umbilicus (type 7) and appeared in the subhepatic space (type 8)

Only seven cases of isolated unilateral rupture of the alar ligament had been previously reported. The authors report the first adult female case of this rare injury. The patient in their case, a 36-year-old female presented after a trauma due to falling, and at that moment, she had fainted due to a sudden pain between the neck and head. The radiological examinations [magnetic resonance imaging (MRI) and X-rays] had been interpreted as normal. She had a positive Alar ligament test at the right side, and a thin section craniovertebral junction computed tomography was obtained which revealed an asymmetrically left-sided odontoid process and a new MRI revealed a right-sided alar ligament rupture. Th us she underwent a bilateral greater occipital nerve block together with pulse radiofrequency and trigger point injection at splenius capitis, levator scapula, and trapezius followed by the application of a halo orthosis to be worn for 3 months. The patient was found to be pain-free in the follow-up examinations. With pure unilateral alar ligament rupture, the atlantooccipital joint is not disrupted and the craniovertebral junction is not destabilized. To date, only eight cases of isolated unilateral alar ligament rupture have been reported one of which was a 25 years old male; all of whom presented with marked neck pain and treated by external immobilization for 4 weeks to 4 months and our case is the first adult female patient.

Amaç: Difüzyon ağırlıklı görüntüleme,beyin dokusunun canlılığı hakkında fikir veren önemli bir yöntem olup kuvvetlimanyetik alan gradientleri kullanılmaktadır. Buna bağlı olarak difüzyonağırlıklı görüntüleme tekniği su moleküllerinin mikroskopik hareketlerindekideğişikliklerin saptanmasını mümkün kılmaktadır. Çalışmamızda, difüzyonağırlıklı görüntüleme ile su moleküllerinin aksonlar boyunca olanhareketlerinden yararlanarak elde edilen Apparent Diffusion Coefficient (ADC)değişikliklerinin yaşa göre değişiminin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmamıza dahil edilen 94 olgununADC haritaları üzerinden korpus kallosumun farklı bölgelerinden ADC değerlerideğerlendirildi.Bulgular: ADC değerinin minimum ve maksimumdeğerleri 0.589-0.819 mm²/sn x 10-³, ortalama ADC değeri ise 0.735 ±0.043 mm²/sn x 10-³ olarak bulunmuştur. Çalışmamızda yaş arttıkça,korpus kallosumun ortalama ADC değerlerinde istatistiksel olarak belirginderecede artış bulunmuştur (p, Objective: Evaluation of corpus callosumby means of diffusion-weighted and conventional magnetic resonance imagingaccording to the age Diffusion-weightedimaging (DWI) is a significant methodthat gives an idea as to the vitality of the brain tissue. DWI is affectedfrom the movements of thepatient at a minimum with its strong magnetic field gradients and is extraordinarily sensitive in reflectionof the changes in the microscopic translationalactivities of the water molecules.Objective of our study is to evaluate by means of diffusion-weighted imaging the ApparentDiffusion Coefficient (ADC) changes byaging which are obtained using the activities of the watermolecules throughout axons. Material and Methods: ADC measurement of corpus callosumat different parts has been studied in 94 patientResults: Minimumand maximum values of the ADCvalue were found as 0.589-0.819 mm²/sn x 10-³ while the average ADC value was found as 0.735 ± 0.043 mm²/sn x 10-³. Our study has revealed a distinctivestatistical increase in the average ADCvalues of corpus callosum in line withaging (p

INAL, MIKAIL/0000-0003-0642-7913 WOS: 000448798800010 Objective: The aim of this study is to examine the diffusional changes in the vitreous humor in multiple sclerosis and Behcet's disease. Materials and Methods: Apparent diffusion coefficient values were investigated in diffusion magnetic resonance imaging scans of a total 111 vitreous, 31 of which were Behcet's disease patients, 40 had multiple sclerosis and 40 were healthy volunteers. Then, multiple sclerosis and Behcet's disease group were statistically compared with healthy volunteers and their apparent diffusion coefficient values amongst themselves. Results: There was no significant difference in terms of age and sex distribution among the three study groups (p>0.05). While there was no significant difference between multiple sclerosis and control groups (p>0.05), apparent diffusion coefficient values of Behcet's patients were significantly lower than multiple sclerosis and control groups (p

Amaç: Difüzyon ağırlıklı görüntüleme ile akut iskemisi olan hastalarda, iskemik“kor” dan ne kadar uzaklıkta görünen difüzyonkatsayısı değerlerinin normale ulaştığının tespiti amaçlandı.Gereç ve Yöntem: Akut iskemisi olan 44 hasta çalışmamıza dahil edildi. Difüzyon ağırlıklıgörüntüleme ile iskemi alanı dış sınırına 4mm, 8mm ve 12 mm uzaklıktan dörderölçüm yapılarak görünen difüzyon katsayısı değerleri elde edildi. Bu değerler simetrik noniskemikhemisfer ile istatistiksel olarak kıyaslandı.Bulgular: Dört ve 8 mm uzaklıktaki dörder ölçümünortalaması noniskemik hemisferdeki simetrik ölçümlerin görünendifüzyon katsayısı değerlerinden istatistiksel olarak anlamlıdüzeyde düşük olarak saptanırken, 12 mm uzaklıkta elde olunan ölçümler ilenoniskemik hemisferdeki ölçümler arasında istatistiksel olarak anlamlıfarklılık saptanmadı.Sonuç: Çalışmamızverileri ışığında ve mevcut hasta grubunda iskemik kor dokusundan 12 mmmesafede görünen difüzyon katsayısıdeğerlerinin; hücresel düzeydedifüzyonun karşı hemisferle eş düzeye geldiği sonucuna varılmıştır. Bumesafenin manyetik rezonans perfüzyon tetkiki ile kurtarılabilir penumbra dokusu ile ne kadarörtüştüğünün saptanması, difüzyon ağırlıklı görüntülemenin kontrastsız ve kısasürede elde edilebilen bir tetkik olarak penumbra tespitinde kullanılabilmeolasılıklarını gündeme getirmektedir., Objective: We aimed toanalyse the distance from the ischemic area where the ADC values normalise.Material and Methods: Forty-four patients with acuteischemia were involved in the study. Apparent diffusion coefficient values are measuredat 4mm, 8mm and 12mm away from the outer boundary of ischemiaand these apparent diffusion coefficient measurements were compared with symmetrical non-ischemic hemisphere.Results: The apparent diffusioncoefficient measurements obtained 4 and 8 mm away from the outer boundary of ischemia, weresignificantly lower than the apparent diffusion coefficient measurements obtained fromsymmetric non-ischemic hemisphere. The measurements obtained 12 mm away fromthe outer boundary were not statistically different from symmetric non-ischemichemisphere.Conclusion: The apparent diffusioncoefficient values seem to be normalised at 12 mm away from the outer boundary of ischemia, which should beanalysed with perfusion weighted studies in order to verify how thesemeasurements can reflect the penumbra tissue.

INAL, MIKAIL/0000-0003-0642-7913 WOS: 000354723700003 PubMed: 24878661 Apparent diffusion coefficient (ADC) values derived from diffusion-weighted MR imaging (DWI) provide important information about tissues. The goal of this study was to evaluate the ADC values in the corticospinal tract regions in multiple sclerosis (MS). The ADC values of 42 patients with multiple sclerosis and 46 healthy people were measured. The ADC values in the corticospinal tract at the capsula interna posterior crus from six points and mesencephalon from three points bilaterally in MS patients were compared with those of controls. An ANOVA post hoc test was used to analyse the differences in mean ADC values between the MS and control groups. The mean ADC values of the right (p = 0.008) and left internal capsules (p = 0.000) and right (p = 0.002) and left mesencephalons (p = 0.044) in MS patients were significantly lower than in the control group. There was no significant difference between the right and left side ADC values in MS (p = 0.313 vs. p = 0.223) and control groups (p = 0.756 vs. p = 0.105), respectively. The mean ADC values of the corticospinal tract in MS patients were significantly lower than in the control group. This decreased diffusion may be the result of cellular infiltration due to inflammation, cytotoxic oedema, demyelination or remyelination processes.

Objective: We aimed to evaluate retrobulbar hemodynamics during healthy and preeclamptic pregnancy. Methods: We studied retrobulbar hemodynamics in 21 healthy pregnant, 20 preeclamptic and 21 non-pregnant fertile women. The peak systolic velocity, end-diastolic velocity and resistivity index (RI) of the ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) were measured by color Doppler imaging. Results: The systolic and diastolic blood pressures of the preeclamptic women (155±8.5 and 105±7.5 mmHg, respectively) were significantly higher than those of healthy pregnant women (110±5.5 and 70±7.5 mmHg, respectively, p=0.008). The RI values of OA, CRA and PCA in healthy pregnant women were significantly lower than those of the non-pregnant women. The RI of the CRA and PCA in preeclamptic women were significantly higher than those of healthy pregnant women. Although there was no statistical significant difference, the RI of the OA was lower in preeclamptic women than healthy pregnant women. Conclusion: Resistance of all retrobulbar arteries decreased during healthy pregnancy. On the other hand, increased resistance was detected in PCA and CRA, besides the nonsignificant decrease in OA during preeclamptic pregnancy. Different auto regulator control mechanisms in response to hypertension seem to be responsible for the different conducts of different sized arteries of orbita during preeclamptic pregnancy. ©Copyright 2012 by Gazi University Medical Faculty.

PubMed: 26468827 Objectives: Technological advancements in the diagnostic radiology recently permitted reviewing the normal anatomy through multidetector computed tomography (MDCT) imagination. The aim of this paper is retrospectively investigation of the clival foramen and canal through MDCT. Materials and Methods: One hundred eighty-six MDCT scans were reviewed. First, images were taken at axial plane, and then coronal and sagittal reconstructions of raw data were performed. Later investigations were carried out on these three-dimensional images (3-D imaging). The images were evaluated as clival foramen ''present'' or ''absent.'' Results: In our 186 patients, evaluation of MDCT showed that clival foramenwas absent in 66.7% (n=124) of patients. Only 33.3% (n=62) of patients had a clival foramen. In 3-D images, clival canal and clival foramen were shown more clearly compared with the MDCT. Conclusions: Knowledge of the clival canal might be useful in patients of questionable clival fracture or during neurosurgical operations in this region. During life the canal contained a vein connecting the basilar plexus with the venous plexus of the vertebral canal, and inferior petrosal sinuses. Before the surgical interventions in the clival region, the presence of the clival canal and foramen should also be known due to its vascular contents. By multidetector computed tomography and 3-D images, clival canal and foramen may be viewed preoperatively. Copyright © 2015 by Mutaz B. Habal, MD.

The main purpose of this study was to determine if hepatocellular carcinomas (HCCs) missed on prospective magnetic resonance (MR) study could be identified on retrospective MR analysis, and to determine the cause for misdiagnosis. Among 555 patients who underwent liver transplantation between 1993 and 2004, 279 were imaged with MR imaging and four of these revealed HCCs in explanted livers that were not reported on prospective MR reading. The main cause of missed lesions were suboptimal image quality due to inability of patients to suspend respiration; other causes were HCC misinterpreted as high-grade dysplastic nodule and isoenhancement of HCC on early phase images. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.

Batislam, Ertan/0000-0002-7493-4573 WOS: 000229592100003 Objectives: In the present study, we aimed to investigate the postural changes of systemic blood pressure, retrobulbar blood flow velocities, and intraocular pressure as a response to sildenafil. Material and methods: A total of 28 healthy volunteers with an average age of 51.4 +/- 0.5 years ( range: 46 - 53 years) were divided into two groups: study group ( Group 1) and control group ( Group 2). After baseline measurements of retrobulbar blood velocity in the ophthalmic, central retinal, and posterior ciliary arteries using color Doppler imaging and intraocular pressure were noted in both groups, sildenafil citrate ( 50 mg) was given to the participants in Group 1. All parameters were then remeasured in the sitting and supine positions. Mann-Whitney U test, Friedman variant analysis, and Wilcoxon two-related sample test were used to evaluate changes of these parameters with regard to position in both groups. Results: Changing from a sitting to a supine position decreased the systolic and diastolic blood pressures in both groups. These changes were not statistically significant between groups ( p > 0.05). Intraocular pressure showed statistically insignificant increases in the supine position in both groups ( p > 0.05). There were no statistically significant differences between the two groups with regard to the retrobulbar hemodynamic parameters in two ( sitting and supine) positions ( p > 0.05). Conclusion: This is the first clinical study on the effects of sildenafil on retrobulbar and systemic hemodynamics in postural variations. Retrobulbar hemodynamics, intraocular pressure, and systemic blood pressure are the same in patients who use recommended doses of sildenafil as in physiological conditions.

WOS: 000225479800011 PubMed: 15556597 We aimed to develop criteria of hepatomegaly on erect plain radiography by comparing the results with those of ultrasonography. Right-sided longitudinal length and second lumbar vertebra ratio, of 22 cm and 6, respectively, detected hepatomegaly with over 90% accuracy, with higher success rates for the lumbar vertebral ratio. Corresponding values for normal size were 20 cm and 5. Sonography revealed high correlation with these results. We concluded that liver size measured on erect plain radiography was larger than but similar to that measured by sonography, and that right-sided longitudinal length and the lumbar vertebral. ratio are reliable criteria showing good correlation with the results of sonography.

We present computed tomography, magnetic resonance imaging and pathologic findings of a 52-year-old female with a giant dedifferentiated retroperitoneal liposarcoma in which well differentiated lipoma-like and dedifferentiated components are found together. Dedifferentiated components of the mass showed various degrees of enhancement and revealed no suppression with fat saturation techniques. The diagnosis of dedifferentiated liposarcoma should be kept in mind when a mass is found with retroperitoneal localization, intense of contrast enhancement, calcifications, invasion of adjacent tissues, necrosis and haemorrhage, and the absence of fat suppression. © 2004 Elsevier Ireland Ltd. All rights reserved.

WOS: 000188065200003 PubMed: 14756348 Objective. To study the effect of anti hypertensive drugs in essential hypertension and in the central retinal, posterior ciliary and ophthalmic arteries by using Doppler sonography. Methods. Thirty patients with essential hypertension and 32 control subjects were enrolled in the study. The pulsatility and resistive indices were evaluated in the central retinal, posterior ciliary and ophthalmic arteries before and 2 months after treatment with anti hypertensive drugs as well as in the control group. The pulsatility and resistive index values for each artery in each group were compared statistically. Results. There were significant differences in the retrobulbar pulsatility and resistive index values in each artery among the patients with initially diagnosed hypertension and the control group (P < .05). There were significant reductions in the resistive and pulsatility index values of the posterior ciliary and ophthalmic arteries after treatment (P < .05). For the ophthalmic artery posttreatment pulsatility and resistive index values did not reach the level of flow measured in the control subjects. Conclusions. The alteration of Doppler parameters of medication-free patients with hypertension may result from a peripheral vasospasm in the retrobulbar circulation, and the improvement in the Doppler parameters with oral anti hypertensive drugs may indicate the importance of early diagnosis in ameliorating hypertension-induced retrobulbar circulation changes.

European Congress of Radiology -- MAR 07-11, 2003 -- VIENNA, AUSTRIA WOS: 000183827100004 PubMed: 12862266 Objectives. For the evaluation of skeletal age, the methods of Greulich-Pyle and Tanner-Whitehouse are generally used in clinical practice. Our investigation was undertaken to determine whether the ultrasonographic version of the Greulich-Pyle atlas is capable of assessing skeletal age. If so, we aimed to describe the standards for the ultrasonographic version of the Greulich-Pyle atlas for each year during the first 6 years of life. Methods. Ninety-seven subjects underwent left hand and wrist radiography and ultrasonographic examination for bone age assessment during a 1.5-year study. Estimated bone ages derived from the plain radiography and "hand and wrist ultrasonography charts" interpreted by use of the Greulich-Pyle atlas were compared statistically. Results. The estimated bone ages from plain radiography and hand and wrist ultrasonography charts interpreted by use of the Greulich-Pyle atlas were significantly correlated; 71.1% of male patients had the same age in both methods, and in 84.4% of patients, the difference was less than 6 months. In 65.5% of female patients, both methods revealed the same age, and in 88.5% of them, the difference was less then 6 months. Conclusions. The ultrasonographic version of the Greulich-Pyle atlas can be used to estimate bone age even in ultrasonography departments. This method is highly correlated and a valid alternative to plain radiography for bone age estimation. This enables estimation of skeletal age in ultrasonography departments easily without exposing the patient to radiation.

INAL, MIKAIL/0000-0003-0642-7913 WOS: 000347167300005 PubMed: 25763192 Introduction: Superior mesenteric artery syndrome is an uncommon cause of duodenal obstruction, and its manifestations are generally associated with compression on the third part of the duodenum between the abdominal aorta and superior mesenteric artery. Case Presentation: In this report, a patient is described presenting with epigastric pain and weight loss due to superior mesenteric artery syndrome. The patient has also nutcracker syndrome, which is the compression of the left renal vein between the aorta and the superior mesenteric artery at its origin. Conclusions: In addition to an appropriate clinical history, CT findings indicating decreased aortomesenteric angle and a shortened aortomesenteric distance can suggest the diagnosis for both the superior mesenteric artery syndrome and accompanying nutcracker syndrome.

INAL, MIKAIL/0000-0003-0642-7913 WOS: 000347164400012 PubMed: 25780548 Background: Surgery of appendicitis carries 7-11% negative appendectomy rates. Sonographically visualized normal appendix precludes unnecessary computed tomography (CT) examination and may reduce negative appendectomy rates. Tissue harmonic imaging (THI) has been reported to improve the overall image quality. Objective: We aimed to assess whether THI is more successful than conventional ultrasonography (US) in detecting normal and pathologic appendices. Patients and Methods: The study was performed on 185 patients who applied for routine US examinations in whom clinical findings of appendicitis were detected in 25. We searched for the appendix; applying both THI and conventional US to each patient, one before and the other after the routine US examinations. Patients were divided into two groups; one was evaluated first with conventional US and the other first with THI. When the appendix was found, localization, diameter and time spent for visualization were recorded. Twelve patients were operated; all of whom had appendicitis pathologically. Two methods were compared for: 1. Success rates in all patients; female, male and child groups separately; 2. Visualization of pathologic and normal appendices; 3. Time for visualization of appendix; 4. Comparison of success rates in the adult and child population. The relationship between the rate of visualization and body mass index was evaluated. Results: The appendix was visualized better by THI in all patients, and in the female and male groups (P < 0.001). In children, both methods were more successful compared to adults (P < 0.001, compared to male group, P < 0.001, compared to female group), with no difference between the methods (P = 0.22). When only the normal appendices were concerned, there was significant difference between both methods (P < 0.000). Both methods detected pathologic appendices better than normal ones, with a higher ratio for THI (P = 0.022 for the THI group, and chi(2) = 7.22, P = 0.07 for the conventional US group). THI visualized the appendix faster. Both methods were more successful in lean patients (P = 0.004 for THI, P = 0.001 for conventional US imaging). Conclusions: THI visualizes appendix better than conventional US. It is a simple and time saving method that may eliminate further diagnostic imaging, and it may decrease negative appendectomy rates and related complications.

INAL, MIKAIL/0000-0003-0642-7913 WOS: 000343525300002 Nutcracker syndrome (NCS) is a rare pathology, caused by compression of the left renal vein (LRV) between the abdominal aorta (AA) and the superior mesenteric artery (SMA), due to reduction of the angle between AA and SMA. This leads to LRV varices, left gonadal vein varices and therefore, the pelvic congestion syndrome. For this reason, coexistence of NCS and pelvic congestion syndrome has been described. It manifests by hematuria, proteinuria, and nonspecific pelvic pain secondary to pelvic congestion, dyspareunia and persistent genital arousal We report a 27-year-old woman who experienced hematuria and left flank pain. The diagnosis of NCS accompanied by pelvic congestion syndrome was missed initially but later on the diagnosis was made by color Doppler ultrasound, abdominal computed tomography (CT) and CT angiography that were later performed. She refused interventional and surgical treatments, and was lost to follow up.

To the Editor, Here, we report an extremely rare endoscopic finding, intramural duodenal diverticulum (IDD), a windsock diverticulum, in a 38-year-old woman who was admitted to our outpatient clinic with the complaint of dyspepsia. Her medical history and physical examination were unremarkable. All laboratory findings, including whole blood count, total biochemistry, erythrocyte sedimentation rate, and C-reactive protein, were in the normal range. Abdominal ultrasonography was normal. An upper gastrointestinal endoscopy revealed antral gastritis, and gastric biopsies were performed for H. pylori infection. Also, a juxtapapillary flat diverticulum was detected in the second portion of the duodenum (Figure 1). When the endoscope was inserted into the diverticulum, there was an orifice approximately 11 mm in diameter at the end of the diverticulum, surrounded with a totally normal mucosa, which revealed that it was a natural orifice (Figure 2). The third portion of the duodenum could be visualized from the orifice. When methylene blue was sprayed from the orifice with a sclerotherapy catheter, it was confirmed that the diverticulum was connected with the third portion of the duodenum via this orifice. Due to the typical endoscopic finding, the diverticulum was thought to be a duodenal windsock diverticulum, and abdominal computerized tomography was performed for possible co-existing gastrointestinal abnormalities, which revealed normal findings. In the follow-up, the patient was symptom free after H. pylori eradication therapy.

WOS: 000353553700065 PubMed: 25910334 …

Castillo, Mauricio/0000-0003-2960-1064 WOS: 000230550800012 PubMed: 15967323 Idiopathic transdural spinal cord herniation (ICSH), a rare condition which may cause progressive myelopathy, can be diagnosed preoperatively by MRI. Surgical treatment usually results in the resolution of symptoms and, thus, familiarity with the imaging findings in this condition impacts patient management. We present the case of a 36-year-old woman in whom the initial MRI findings were thought to be consistent with only an arachnoid cyst compressing the spinal cord. After surgery, her symptoms remained unchanged, and a repeat MRI study was interpreted as being compatible with a transdural spinal cord herniation. Repeated surgery with reduction of the herniation resulted in significant clinical improvement. (c) 2005 Elsevier Inc. All rights reserved.

WOS: 000307670000022 PubMed: 21724354 Purpose: To test the reproducibility of apparent diffusion coefficients (ADC) measurements of the normal liver, kidney and spleen parenchyma with different b values. Materials and methods: Eleven healthy volunteers were imaged twice with use of the same protocol. Each DWI was performed with b-factors of 0, 100 and 500s/mm(2). The ADCs were organized according to session (1 or 2), anatomic location and repetition (twice with two different b value per session). The ADC data were analyzed with repeated-measures analysis of variance to demonstrate the influence of anatomic location, session and different b values. The coefficient of variation was calculated for each subject, b value and anatomic location, then analyzed by using repeated-measures analysis of variance. Results: There were significant differences in mean ADCs among the three anatomic locations and with different b values (P < .05). There were no significant differences in ADCs between imaging sessions 1 or 2 for both b values (P > .05). The CV values range between 7.3% and 14.7%. There were no significant differences in CV values neither between the two b values nor for the various organ locations (P > .05). Conclusion: Using the same technical parameters, patients and the same observer, CV values range between 7.3% and 14.7%. And we recommend to be careful in examination and comparison of the measured ADC values, below these limits, without knowledge technical parameters that has been used, otherwise differences that are merely because of changes in the measurement technique could be interpreted as differences because of progression of disease or therapy. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

WOS: 000346647500010 PubMed: 25216755 …

WOS: 000249820100010 PubMed: 17607091 Background and aims: This study aimed to determine whether there is an adrenomedullin (AM)-mediated protective effect of postmenopausal estroger/progestin therapy (HRT) against cardiovascular disorders. Methods: A total of 22 post-menopausal women without hysterectomy undergoing postmenopausal symptoms (aged 43-52) were treated with conjugated equine estrogen (0.625 mg/die) plus medroxyprogesterone acetate (2.5 mg/die) for six months. The flow velocity of the right middle cerebral artery [measured as resistance index (RI) and pulsatility index (PI)], plasma levels of adrenomedullin and endothelin-1 (ET-1), mean baseline ratio of AM to ET-1, and lipid profiles were assessed before and after HRT. Results: A statistically significant difference was found for triglycerides, total cholesterol, AM/ET-1 ratio and right middle cerebral artery PI (p < 0.05), without any significant differences in HDL, LDL, AM, ET-1, systolic blood pressure, diastolic blood pressure, a right middle cerebral artery RI (p > 0.05) between pre- and post-HRT. Conclusions: Adrenomedullin may be added to other vasoactive peptides as a new potential candidate for HRT-mediated vascular protection. The ratio of AM/ET-1 vs AM or ET-1 alone may be a useful biological marker of this protection.

WOS: 000237091700015 PubMed: 16429266 We searched for the surgically risky anatomic variations of sphenoid sinus and aimed to compare axial and coronal tomography in detection of these variations. Fifty-six paranasal tomography images (112 sides) were evaluated for coronal, axial and both coronal and axial images. Tomographic findings including bony septum extending to optic canal or internal carotid artery; protrusions and dehiscences of the walls of internal carotid artery, optic nerve, maxillary nerve and vidian nerve; extreme medial course of internal carotid artery; patterns of aeration of the anterior clinoid process; and Onodi cells were evaluated. The results were classified as "present, absent, suspicious-thin (only for dehiscence) or no-consensus". The results of each plane were compared with that of the result of the both planes together. Kappa coefficient and Chi-square tests were used to compare both planes. Twelve cadaveric dissections were performed to reveal the proximity of sphenoid sinus to surgically risky anatomic structures. Endoscopy was applied to five cadavers. 18 evaluations were classified as 'no-consensus'. We detected 34, 35, 34 and 40 protrusions of internal carotid artery, optic nerve, maxillary nerve, vidian nerve, respectively. Dehiscences were present in 6, 9, 4 and 8, and suspicious-thin in 8, 10, 16 and 25 in canals of internal carotid artery, optic nerve, maxillary nerve and vidian nerve, respectively. Bony septum to internal carotid artery and optic nerve was observed in 30 and 22 cases. We observed 9 extreme medial courses of internal carotid artery, 27 aerated clinoid process and 9 Onodi cells. Axial images were superior in detection of bony septum to internal carotid artery and Onodi cells; while the coronal images were more successful in detection of protrusion of optic nerve and vidian nerve, and dehiscense of maxillary nerve and vidian nerve (P < 0.05). In cadaveric dissections, the septa were inserted into the bony covering of the carotid arteries in two sinuses (8.3%). Detailed preoperative analysis of the anatomy of the sphenoid sinus and its boundaries is crucial in facilitating entry to the pituitary fossa and reducing intraoperative complications. Coronal tomography more successfully detects the sphenoid sinus anatomic variations.

WOS: 000227685200006 PubMed: 15756661 Purpose. We used Doppler sonography to determine the resistance index (RI) and pulsatility index (PI) of the normal lacrimal artery (LA) in both females and males. We also compared the values obtained at various periods of reproductive life. Methods. The study was performed in 25 prepubertal girls, 28 females of reproductive age, and 27 postmenopausal women, 23 pregnant women, and 104 healthy males. Doppler sonography was used to determine the RI and PI of the LA. Results. The mean PI for the entire patient population was 1.48 +/- 0.60 and the RI was 0.72 +/- 0.09. The RI and PI values of the LA did not differ between males and females. Similarly, the mean RI and PI values of the LA did not change significantly between the various reproductive phases. Conclusion. The PI and Rl of the lacrimal gland are similar in both sexes. Moreover, they are not altered by changes in levels of sex steroids. (c) 2005 Wiley Periodicals, Inc. J Clin Ultrasound 33:123-126, 2005; Published online in Wiley InterScience (www.interscience.wiley.com).

Batislam, Ertan/0000-0002-7493-4573 WOS: 000227307000045 Abscess as a complication of extracorporeal shock wave lithotripsy is a rare condition, We present the computed tomography findings of an abdominal wall abscess that occurred after extracorporeal shock wave lithotripsy for which prophylactic antibiotics had not been given. The abscess destroyed the posterior abdominal wall muscles and dissected into the thorax. The muscles were thickened and showed enhancement. A parenchymal defect in the right kidney adjacent to a caliceal stone, with strands extending from this defective region to the abscess, was observed, and was thought to be the result of parenchymal destruction caused by the shock waves. Other parts of the kidney and psoas muscle were normal. Microbiologic examination revealed Escherichia coli. UROLOGY 65: 389.e16-389.e18, 2005. (C) 2005 Elsevier Inc.

The objective of this study was to determine whether ultrasonography is a reliable method for monitoring subcutaneous fat thickness in the quantitative analysis of liposuction results. Subcutaneous fat thicknesses before and 2 months after liposuction in prespecified areas were measured in 14 patients using a 7.5-MHz ultrasound scanner. Pre- and postoperative subcutaneous fat thicknesses were compared statistically. The thicknesses of pre- and postoperative subcutaneous fat layers were statistically different. Ultrasound is a valuable tool for perioperative guidance, preoperative planning, and quantitative analysis of the procedure results.

We describe the MR appearance of breast cancer metastases to the stomach. The stomach wall was diffusely thickened with loss of the regular fold pattern best shown on the single shot T2-weighted images and enhanced with moderate mural enhancement on early and late post gadolinium images. The combination of gastric wall thickening and abnormal enhancement should suggest the diagnosis of diffuse mural metastases in a woman with a history of breast cancer.

We report the MRI findings of primary small-cell carcinoma of the kidney (PSCCK) in a 59-year-old female. This tumor appeared as a 16-cm mass that arose from the right kidney. This lesion had diminished signal on T1-weighted images and heterogeneous mixed signal on T2-weighted images. The tumor primarily involved the renal medulla with persistent thin renal cortex. Despite the tumors' large size, no substantial central necrosis was present. The predominant medullary location and the lack of central necrosis in this large tumor were features unusual for renal cell carcinoma and should raise the suspicion of another malignancy, the differential diagnosis of which should contain extrapulmonary small-cell carcinoma of the kidney.

4th International Glaucoma Symposium -- MAR 19-22, 2003 -- Barcelona, SPAIN WOS: 000223473200008 PubMed: 15281970 Purpose: To determine the short-term effects of latanoprost on retrobulbar circulation in ocular hypertension. Methods: Forty-six eyes of 23 consecutive bilateral ocular hypertensive patients with an intraocular pressure (IOP) of greater than 22 mmHg were evaluated in a prospective controlled study. All subjects received a single drop of latanoprost 0.005% in one eye and placebo in the fellow control eye. Systemic circulatory parameters, intraocular pressure, blood flow velocities, and resistance indices of the ophthalmic, short posterior ciliary and central retinal arteries were measured using colour Doppler imaging at baseline and 2 h and 8 h after dosing, Results: Latanoprost lowered IOP significantly after 2 h and 8 h (P < 0.01). The mean IOP reduction was 6.7 mmHg 8 h after dosing. At baseline, there were no statistically significant differences in any retrobulbar vessels of eyes that received a single drop of latanoprost when compared with the eyes that received placebo (P > 0.05). Comparisons with baseline and latanoprost conditions revealed that latanoprost did not alter the blood flow velocities and resistance indices in the ophthalmic (P > 0.05), posterior ciliary (P > 0.05) and central retinal (P > 0.05) arteries 2 h and 8 h after dosing. The systolic and diastolic blood pressures (P = 0.74, P = 0.29, respectively) and pulse rate (P = 0.68) remained unchanged over the 8-h period. Conclusions: This study found that a single drop of latanoprost significantly reduces intraocular pressure 8 h after dosing. However, it does not have any short-term effects on the retrobulbar haemodynamics in ocular hypertensive eyes.

WOS: 000226437100005 PubMed: 15653228 We aimed to assess the hemodynamic effects of nonionic low-osmolarity contrast media (CM) on kidneys with ureteral stone (KUS). A total of 16 patients with KUS (group A) and 25 control patients (group B) were evaluated with Doppler ultrasound (US) bilaterally for main (MRA), interlobar (ILA) and arcuate renal arteries (ARA), before and 15 min after CM for IV pyelography. Peak systolic (PSV) and end diastolic velocities (EDV) and resistance index (RI) were measured. Data were analyzed by ANOVA and t-test. In group A. CM induced increase in PSV of MRA of contralateral kidney (p = 0.021) and decrease in PSV of ILA (p = 0.024) decrease in PSV and EDV and increase in RI of ARA of KUS (p = 0.010. 0.005. 0.027. respectively). CM induced hypoperfusion in KUS and compensatory changes in contralateral kidneys. similar to the effects of diuresis or mannitol. We conclude that the effect of CM on KUS is related to its osmolar load. (C) 2005 World Federation for Ultrasound in Medicine Biology.

The hemodynamic effects of propofol-fentanyl anesthesia were known to reduce arterial pressure and heart rate. We aimed to determine the effects of propofol-fentanyl anesthesia on renal artery blood flow and aorta by using Doppler ultrasonography on an animal model.The study was conducted on 8 male New Zaeland White strain rabbits. The initial aortic and renal hemodynamic measurements were determined on animals using ketamin anesthesia. Later the right femoral arteries were cannulated for determining arterial blood pressure and pulse oximetry was followed from the ear. Propofol 5-7 mg/kg with fentanyl 1-2 microg/kg was injected via the ear vein. Doppler parameters (RI, RI, Vmax, Vmin) of the renal artery and aorta were determined after the anesthesia.According to the basal measurements, arterial blood pressure and breath rates declined significantly (27% and 53% respectively, p0.05); however there were no statistical alteration of aortic and renal artery Doppler parameters.Anesthesia induced by propofol-fentanyl did not induce a statistically significant difference in Doppler parameters obtained from the renal artery and aorta. It is clinically important to know that determining the changes in RI and PI during the postoperative period is not related to the propofol-fentanyl anesthesia.

WOS: 000228856700006 PubMed: 15864621 Purpose: To evaluate the cerebral blood flow velocity in patients with ocular hypertension. Material and methods: Twenty-four ocular hypertensive patients and 24 age- and sex-matched healthy volunteers were recruited in a prospective comparative study. All subjects had normal findings on full-threshold visual field tests and clinically normal optic nerves. All patients with ocular hypertension had an intraocular pressure (IOP) of > 21 mmHg on three separate occasions without treatment. Systolic and diastolic blood pressure by cuff, heart rate by palpation, IOP by Goldmann applanation tonometry, central corneal thickness by ultrasound pachymetry, blood flow velocities, and pulsatility index of the ipsilateral middle cerebral artery by transcranial color Doppler were measured. Results: Systolic and diastolic blood pressures ( P= 0.40 and P= 0.45, respectively), heart rate ( P= 0.30), and central corneal thickness ( P= 0.23) were similar in each group. Peak and end-diastolic blood flow velocities in the middle cerebral artery did not differ between ocular hypertensives and controls ( P= 0.37 and P= 0.87, respectively). In addition, pulsatility index did not significantly differ between ocular hypertensives and controls ( P= 0.61). Conclusions: The results of this study suggest that ocular hypertension is not associated with reduction in blood flow velocity and elevation of resistance in the middle cerebral artery.

We report a case with a defect in the medial orbital wall, causing a protrusion of orbital contents into the ethmoidal cells. Both the coronal and axial computed tomography of the paranasal sinuses demonstrated the protrusion and focal wall defect properly. © 2004 Elsevier Ireland Ltd. All rights reserved.

WOS: 000223113900007 PubMed: 15284462 Objective. We aimed to search for differences between observers and automatic and manual measurements in calculations of Doppler parameters. Methods. The middle cerebral artery (MCA), central retinal artery, ophthalmic artery (OA), common carotid artery (CCA), vertebral artery (VA), popliteal artery (PA), interlobar renal artery (IRA), and arcuate renal artery (ARA) were evaluated in 20 healthy subjects bilaterally Peak systolic velocity (PSV), end-diastolic velocity (EDV), time-averaged maximum velocity (TAMAX), resistive index (RI), and pulsatility index (Pi) were measured from the same spectrum manually by 3 observers and automatically. Results of 4 measurements were compared by analysis of variance and Pearson tests. Results. The comparison of the 4 measurements revealed significant differences for most parameters except TAMAX of the OA, VA, and ARA and PSV EDV and PI of the PA. An automatic calculator yielded lower PSV, RI, and PI values (except the MCA and PA) and higher EDV values compared with manual measurements. The magnitudes of difference were in the range of 1% to 16% for velocities and 4% to 14% for RI and PI. The means of difference were 3.185 cm/s for PSV of the CCA and 0.054 for RI of the IRA. Correlation was high for PSV, EDV, and TAMAX in all arteries (except TAMAX of PA) and relatively low for PI and RI in most of the arteries. Conclusions. Although our study was performed on healthy subjects, our results showed that, in most cases, readers and the automatic approach disagreed on evaluation of Doppler parameters. This may be important in preventing false diagnoses in cases with Doppler values close to upper limits and may necessitate establishment of new limits for each method.

WOS: 000189274900005 PubMed: 14663592 Purpose. To quantify the retrobulbar hemodynamics of patients with ocular hypertension and open-angle glaucoma and to compare it with that of normal subjects. Methods. Nineteen eyes of 19 ocular hypertensive patients, 19 eyes of 19 open-angle glaucoma patients and 19 eyes of 19 normal subjects were recruited from our clinic and underwent color Doppler imaging evaluation of the ophthalmic, posterior ciliary, and central retinal arteries. The peak systolic and end-diastolic blood flow velocities and resistivity indices of all retrobulbar vessels were measured. Results. The retrobulbar blood flow velocities were lower and resistivity indices were higher in all retrobulbar vessels in ocular hypertensive patients than in normal subjects. The differences, however, did not reach statistical significance (P>0.05). Glaucoma patients had lower end-diastolic velocities and higher resistivity indices than did normal subjects in the ophthalmic (P=0.003 and P=0.003, respectively), posterior ciliary (P=0.001 and P