84 results on '"Yasar Z"'
Search Results
2. Different modulation schemes for direct and external modulators based on various laser sources.
- Author
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El-Hageen, Hazem M., Kuppusamy, P.G., Alatwi, Aadel M., Sivaram, M., Yasar, Z. Ahamed, and Zaki Rashed, Ahmed Nabih
- Subjects
LASERS ,SIMULATION software ,ELECTRONIC modulators - Abstract
Different types of laser source modulation techniques have been used in various applications depending on the objective. As optical systems extract the laws and the best solutions from experiments and simulations, the present study uses simulation software with different modulation types so the output signals can be compared. The modulators used are Mach-Zehnder, which is an external modulator, and electro-absorption modulator and laser rate equation modulator, which are direct modulators. All these types have an optical link multimode (MM) fiber with a photodiode in the receiver end that can be modeled. The input and output signals are analyzed using different types of modulations. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. Decoding myasthenia gravis: advanced diagnosis with infrared spectroscopy and machine learning
- Author
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Feride Severcan, Ipek Ozyurt, Ayca Dogan, Mete Severcan, Rafig Gurbanov, Fulya Kucukcankurt, Birsen Elibol, Irem Tiftikcioglu, Esra Gursoy, Melike Nur Yangin, and Yasar Zorlu
- Subjects
Medicine ,Science - Abstract
Abstract Myasthenia Gravis (MG) is a rare neurological disease. Although there are intensive efforts, the underlying mechanism of MG still has not been fully elucidated, and early diagnosis is still a question mark. Diagnostic paraclinical tests are also time-consuming, burden patients financially, and sometimes all test results can be negative. Therefore, rapid, cost-effective novel methods are essential for the early accurate diagnosis of MG. Here, we aimed to determine MG-induced spectral biomarkers from blood serum using infrared spectroscopy. Furthermore, infrared spectroscopy coupled with multivariate analysis methods e.g., principal component analysis (PCA), support vector machine (SVM), discriminant analysis and Neural Network Classifier were used for rapid MG diagnosis. The detailed spectral characterization studies revealed significant increases in lipid peroxidation; saturated lipid, protein, and DNA concentrations; protein phosphorylation; PO2 -asym + sym /protein and PO2 -sym/lipid ratios; as well as structural changes in protein with a significant decrease in lipid dynamics. All these spectral parameters can be used as biomarkers for MG diagnosis and also in MG therapy. Furthermore, MG was diagnosed with 100% accuracy, sensitivity and specificity values by infrared spectroscopy coupled with multivariate analysis methods. In conclusion, FTIR spectroscopy coupled with machine learning technology is advancing towards clinical translation as a rapid, low-cost, sensitive novel approach for MG diagnosis.
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- 2024
- Full Text
- View/download PDF
4. High Intensity Interval Training (HIIT) as a Potential Countermeasure for Phenotypic Characteristics of Sarcopenia:A Scoping Review
- Author
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Hayes, L.D., Elliott, B.T., Yasar, Z., Bampouras, T.M., Sculthorpe, N.F., Sanal-Hayes, N.E.M., Hurst, C., Hayes, L.D., Elliott, B.T., Yasar, Z., Bampouras, T.M., Sculthorpe, N.F., Sanal-Hayes, N.E.M., and Hurst, C.
- Abstract
Background: Sarcopenia is defined as a progressive and generalized loss of skeletal muscle quantity and function associated predominantly with aging. Physical activity appears the most promising intervention to attenuate sarcopenia, yet physical activity guidelines are rarely met. In recent years high intensity interval training (HIIT) has garnered interested in athletic populations, clinical populations, and general population alike. There is emerging evidence of the efficacy of HIIT in the young old (i.e. seventh decade of life), yet data concerning the oldest old (i.e., ninth decade of life onwards), and those diagnosed with sarcopenic are sparse. Objectives: In this scoping review of the literature, we aggregated information regarding HIIT as a potential intervention to attenuate phenotypic characteristics of sarcopenia. Eligibility Criteria: Original investigations concerning the impact of HIIT on muscle function, muscle quantity or quality, and physical performance in older individuals (mean age ≥60 years of age) were considered. Sources of Evidence: Five electronic databases (Medline, EMBASE, Web of Science, Scopus, and the Cochrane Central Register of Controlled Trials [CENTRAL]) were searched. Methods: A scoping review was conducted using the Arksey and O'Malley methodological framework (2005). Review selection and characterization were performed by two independent reviewers using pretested forms. Results: Authors reviewed 1,063 titles and abstracts for inclusion with 74 selected for full text review. Thirty-two studies were analyzed. Twenty-seven studies had a mean participant age in the 60s, two in the 70s, and three in the 80s. There were 20 studies which examined the effect of HIIT on muscle function, 22 which examined muscle quantity, and 12 which examined physical performance. HIIT was generally effective in Improving muscle function and physical performance compared to non-exercised controls, moderate intensity continuous training, or pre-HIIT (study
- Published
- 2021
5. Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey
- Author
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Ozlu, Tevfik, Bulbul, Yilmaz, Aydin, Derya, Tatar, Dursun, Kuyucu, Tulin, Erboy, Fatma, Koseoglu, Handan Inonu, Anar, Ceyda, Sunnetcioglu, Aysel, Gulhan, Pinar Yildiz, Sahin, Unal, Ekici, Aydanur, Duru, Serap, Ulasli, Sevinc Sarinc, Kurtipek, Ercan, Gunay, Sibel, Okutan, O., Yildiz, B. P., Cetinkaya, P. D., Arslan, S., Cakmak, G., Cirak, A. K., Sarioglu, N., Kocak, N. D., Akturk, U. A., Demir, M., Kilic, T., Dalli, A., Hezer, H., Altintas, N., Acat, M., Dagli, C. E., Kargi, A., Yakar, F., Kirkil, G., Baccioglu, A., Gedik, C., Intepe, Y. S., Karadeniz, G., Onyilmaz, T., Saylan, B., Baslilar, S., Sariman, N., Ozkurt, S., Arinc, S., Kanbay, A., Yazar, E. E., Yildirim, Z., Kadioglu, E. E., Gul, S., Sengul, A., Berk, S., Dikis, O. S., Kurt, O. K., Arslan, Y., Erol, S., Korkmaz, C., Balaban, A., Erbay, Toru U., Sogukpinar, O., Uzaslan, E. K., Babaoglu, E., Bahadir, A., Baris, S. A., Ugurlu, A. O., Ilgazli, A. H., Fidan, F., Kararmaz, E., Guzel, A., Alzafer, S., Cortuk, M., Hocanli, I., Ortakoylu, M. G., Erginel, M. S., Yaman, N., Erbaycu, A. E., Demir, A., Duman, D., Tanriverdi, H., Yavuz, M. Y., Sertogullarindan, B., Ozyurt, S., Bulcun, E., Yuce, G. D., Sariaydin, M., Ayten, O., Bayraktaroglu, M., Tekgul, S., Erel, F., Senyigit, A., Kaya, S. B., Ayik, S., Yazici, O., Akgedik, A., Yasar, Z. A., Hayat, E., Kalpaklioglu, F., Sever, F., Sarac, P., Ugurlu, E., Kasapoglu, U. S., Gunluoglu, G., Demirci, N. Y., Bora, M., Talay, F., Ozkara, B., Yilmaz, M. U., Yavsan, D. M., Cetinoglu, E. D., Balcan, M. B., Ciftci, T., Havan, A., Gok, A., Nizam, M., Investigators, R.I.M.P.A.C.T. Study, Acibadem University Dspace, Maltepe Üniversitesi, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Talay, Fahrettin, OMÜ, Tıp Fakültesi, Kırıkkale Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi, [Ozlu, Tevfik -- Bulbul, Yilmaz] Karadeniz Tech Univ, Sch Med, Dept Chest Dis, TR-61080 Trabzon, Turkey -- [Aydin, Derya] Pulm Dis Hosp, Chest Dis Clin, Balikesir, Turkey -- [Tatar, Dursun -- Anar, Ceyda] Dr Suat Seren Pulm Dis & Thorac Surg Educ & Res H, Dept Pulm Dis, Izmir, Turkey -- [Kuyucu, Tulin] Sureyyapasa Pulm Dis & Thorac Surg Educ & Res Hos, Dept Pulm Dis, Istanbul, Turkey -- [Erboy, Fatma] Bulent Ecevit Univ, Sch Med, Dept Chest Dis, Zonguldak, Turkey -- [Koseoglu, Handan Inonu] Gaziosmanpasa Univ, Sch Med, Dept Chest Dis, Tokat, Turkey -- [Sunnetcioglu, Aysel] Yuzuncu Yil Univ, Sch Med, Dept Chest Dis, Van, Turkey -- [Gulhan, Pinar Yildiz] Tosya State Hosp, Chest Dis Clin, Kastamonu, Turkey -- [Sahin, Unal] Recep Tayyip Erdogan Univ, Sch Med, Dept Chest Dis, Rize, Turkey -- [Ekici, Aydanur] Kirikkale Univ, Sch Med, Dept Chest Dis, Kirikkale, Turkey -- [Duru, Serap] Diskapi Yildirim Beyazid Educ & Res Hosp, Dept Pulm Dis, Ankara, Turkey -- [Ulasli, Sevinc Sarinc] Hacettepe Univ, Sch Med, Dept Chest Dis, Ankara, Turkey -- [Kurtipek, Ercan] Konya Educ & Res Hosp, Dept Pulm Dis, Konya, Turkey -- [Gunay, Sibel] Afyon State Hosp, Chest Dis Clin, Afyon, Turkey -- [Okutan, O. -- Ayten, O.] Haydarpasa Hosp, Gulhane Mil Med Acad, Dept Chest Dis, Istanbul, Turkey -- [Yildiz, B. P. -- Yazar, E. E. -- Gul, S. -- Bahadir, A. -- Ortakoylu, M. G. -- Bayraktaroglu, M. -- Gunluoglu, G. -- Nizam, M.] Pulm Dis & Thorac Surg Educ & Res Hosp Yedikule, Istanbul, Turkey -- [Cirak, A. K. -- Karadeniz, G. -- Erol, S. -- Erbaycu, A. E. -- Demir, A. -- Yavuz, M. Y. -- Tekgul, S. -- Sever, F. -- Yilmaz, M. U.] Dr Suat Seren, Izmir, Turkey -- [Kocak, N. D. -- Akturk, U. A. -- Arinc, S. -- Sogukpinar, O. -- Duman, D. -- Kasapoglu, U. S.] Sureyyapasa, Istanbul, Turkey -- [Cetinkaya, P. D.] Educ & Res Hosp Numune, Adana, Turkey -- [Dikis, O. S. -- Bora, M.] Sevket Yilmaz, Bursa, Turkey -- [Balaban, A.] Evliya Celebi, Kutahya, Turkey -- [Yuce, G. D.] Diskapi Yildirim Beyazid, Ankara, Turkey -- [Arslan, S. -- Berk, S.] Cumhuriyet Univ, Sch Med, Dept Chest Dis, Sivas, Turkey -- [Sarioglu, N. -- Erel, F.] Balikesir Univ, Balikesir, Turkey -- [Demir, M. -- Senyigit, A.] Dicle Univ, Diyarbakir, Turkey -- [Kilic, T. -- Kaya, S. B.] Inonu Univ, Malatya, Turkey -- [Dalli, A. -- Ayik, S.] Katip Celebi Univ, Izmir, Turkey -- [Altintas, N.] Namik Kemal Univ, Tekirdag, Turkey -- [Acat, M. -- Cortuk, M. -- Yazici, O.] Karabuk Univ, Karabuk, Turkey -- [Dagli, C. E. -- Akgedik, A.] Ordu Univ, Ordu, Turkey -- [Kargi, A. -- Kurt, O. K. -- Yasar, Z. A. -- Talay, F.] Abant Izzet Baysal Univ, Bolu, Turkey -- [Yakar, F. -- Hayat, E.] Bezmialem Vakif Univ, Istanbul, Turkey -- [Kirkil, G.] Firat Univ, Elazig, Turkey -- [Baccioglu, A. -- Bulcun, E. -- Kalpaklioglu, F.] Kirikkale Univ, Kirikkale, Turkey -- [Gedik, C. -- Kanbay, A.] Medeniyet Univ, Istanbul, Turkey -- [Intepe, Y. S.] Bozok Univ, Yozgat, Turkey -- [Sariman, N.] Maltepe Univ, Istanbul, Turkey -- [Ozkurt, S. -- Ugurlu, E.] Pamukkale Univ, Denizli, Turkey -- [Yildirim, Z. -- Demirci, N. Y.] Gazi Univ, Ankara, Turkey -- [Korkmaz, C. -- Yavsan, D. M.] Necmettin Erbakan Univ, Konya, Turkey -- [Erbay, Toru U.] Dumlupinar Univ, Kutahya, Turkey -- [Uzaslan, E. K. -- Cetinoglu, E. D.] Uludag Univ, Bursa, Turkey -- [Baris, S. A. -- Ilgazli, A. H. -- Ciftci, T.] Kocaeli Univ, Kocaeli, Turkey -- [Fidan, F. -- Havan, A.] Fatih Univ, Istanbul, Turkey -- [Guzel, A. -- Gok, A.] Ondokuz Mayis Univ, Samsun, Turkey -- [Alzafer, S.] Acibadem Univ, Bakirkoy Hosp, Istanbul, Turkey -- [Erginel, M. S.] Osmangazi Univ, Eskisehir, Turkey -- [Tanriverdi, H.] Bulent Ecevit Univ, Zonguldak, Turkey -- [Sertogullarindan, B.] Yuzuncu Yil Univ, Van, Turkey -- [Ozyurt, S.] Recep Tayyip Erdogan Univ, Rize, Turkey -- [Sariaydin, M.] Afyon Kocatepe Univ, Afyon, Turkey -- [Onyilmaz, T. -- Sarac, P.] State Hosp Mardin, Mardin, Turkey -- [Arslan, Y. -- Ozkara, B.] Etimesgut Mil Hosp, Ankara, Turkey -- [Ugurlu, A. O. -- Balcan, M. B.] Baskent Univ, Istanbul Hosp, Istanbul, Turkey -- [Yaman, N.] Pulm Dis Hosp, Balikesir, Turkey, intepe, yavuz selim -- 0000-0002-5697-5291, Sertogullarindan, Bunyamin -- 0000-0002-1478-1990, and Bulbul, Yilmaz -- 0000-0002-8488-3650
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Acute Exacerbations ,Pulmonary and Respiratory Medicine ,lcsh:Diseases of the circulatory (Cardiovascular) system ,medicine.medical_specialty ,Coverage ,pneumococcal vaccine ,Exacerbation ,disease exacerbation ,influenza vaccine ,Influenza vaccine ,Copd Exacerbation ,Self-Reported Influenza ,Chronic Obstructive Pulmonary Disease Exacerbation ,Latin-American Cities ,Logistic regression ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Prevalence ,medicine ,chronic obstructive pulmonary disease exacerbation ,Adults ,Mass index ,030212 general & internal medicine ,Determinants ,lcsh:RC705-779 ,COPD ,business.industry ,Chronic obstructive pulmonary disease ,chronic obstructive pulmonary ,Retrospective cohort study ,lcsh:Diseases of the respiratory system ,Frequency ,medicine.disease ,Vaccination ,030228 respiratory system ,Pneumococcal vaccine ,lcsh:RC666-701 ,Pneumococcal Vaccination ,Original Article ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Abstract
WOS: 000455908800007, PubMed ID: 30745939, OBJECTIVE: The purpose of this study is to detect the prevalence and the factors associated with influenza and pneumococcal vaccination and outcomes of vaccination during 2013-2014 season in patients with chronic obstructive pulmonary disease (COPD) in Turkey. METHODS: This was a multicenter retrospective cohort study performed in 53 different centers in Turkey. RESULTS: During the study period, 4968 patients were included. COPD was staged as GOLD 1-2-3-4 in 9.0%, 42.8%, 35.0%, and 13.2% of the patients, respectively. Influenza vaccination rate in the previous year was 37.9%; and pneumococcus vaccination rate, at least once during in a life time, was 13.3%. Patients with older age, higher level of education, more severe COPD, and comorbidities, ex-smokers, and patients residing in urban areas had higher rates of influenza vaccination. Multivariate logistic regression analysis showed that advanced age, higher education levels, presence of comorbidities, higher COPD stages, and exacerbation rates were associated with both influenza and pneumococcal vaccination. The number of annual physician/outpatient visits and hospitalizations due to COPD exacerbation was 2.73 +/- 2.85 and 0.92 +/- 1.58 per year, respectively. Patients with older age, lower education levels, more severe COPD, comorbid diseases, and lower body mass index and patients who are male and are residing in rural areas and vaccinated for influenza had significantly higher rates of COPD exacerbation. CONCLUSIONS: The rates of influenza and pneumococcal vaccination in COPD patients were quite low, and the number of annual physician/outpatient visits and hospitalizations due to COPD exacerbation was high in Turkey. Advanced age, higher education levels, comorbidities, and higher COPD stages were associated with both influenza and pneumococcal vaccination.
- Published
- 2019
6. Border Surveillance System using Computer Vision
- Author
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Ahamed Yasar Z, Hari Kumar G, Dinesh Kumar R, and Aadarsh S
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021110 strategic, defence & security studies ,business.product_category ,business.industry ,Computer science ,0211 other engineering and technologies ,020206 networking & telecommunications ,02 engineering and technology ,Software ,Arduino ,Buzzer ,0202 electrical engineering, electronic engineering, information engineering ,Computer vision ,Artificial intelligence ,business ,Digital camera - Abstract
The surveillance of border areas or any other secured places using security guards at each and every moments is difficult. It is made possible using digital cameras, a device which is used widely now a days for surveillance purposes. In such a case, the following paper defines the border surveillance system. This is done by computer vision. The requirements includes a camera, Raspberry-pi, Arduino-UNO and Buzzer. The digital camera is used to capture the live movements. The attained information/records are sent as an input to the raspberry pi which uses a computer vision (open CV) software to detect the objects and faces as positive and negative. The corresponding coding is done using python. If any mismatched objects or face (negative) is detected, automatically a signal is sent from the pi module. The desired signal is sent to the authority or monitoring room using transmitter. At one end, the Raspberry-pi module is connected with a monitor, transmitter and at the other end, a receiver with Arduino and buzzer. When any signal is received by a receiver, it is passed to the Arduino, which in turn triggers the buzzer connected to the Arduino and gives an alert signal or sound as it was programmed. In addition to this, the live streaming video can be seen in the monitor/display connected to the raspberry-pi. This surveillance system using computer vision can also be used at various places which are being under surveillances and are secured.
- Published
- 2020
7. Different modulation schemes for direct and external modulators based on various laser sources
- Author
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El-Hageen, Hazem M., primary, Kuppusamy, P.G., additional, Alatwi, Aadel M., additional, Sivaram, M., additional, Yasar, Z. Ahamed, additional, and Zaki Rashed, Ahmed Nabih, additional
- Published
- 2020
- Full Text
- View/download PDF
8. Border Surveillance System using Computer Vision
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Yasar Z., Ahamed, primary, Kumar R., Dinesh, additional, Aadarsh, S., additional, and Kumar G., Hari, additional
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- 2020
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- View/download PDF
9. Does gestational age affect ultrasonographic findings of the hip in preterm newborns? A sonographic study of the early neonatal period
- Author
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Yilmaz, M. U., Erel, F., Senyigit, A., Sever, F., Sarac, P., Ugurlu, E., Kasapoglu, U. S., Gunluoglu, G., Yavsan, D. M., Cetinoglu, E. D., Balcan, M. B., Ciftci, T., Havan, A., Gok, A., Nizam, M., Ozkara, B., ÖZLÜ, TEVFİK, Aydin, Derya, Tatar, Dursun, Kuyucu, Tulin, ERBOY, FATMA, İNÖNÜ KÖSEOĞLU, HANDAN, Anar, Ceyda, Sünnetçioğlu, Aysel, Gulhan, Pinar Yildiz, BÜLBÜL, YILMAZ, Okutan, O., Yildiz, B. P., Cetinkaya, P. D., Arslan, S., Cakmak, G., Cirak, A. K., Yakar, F., Kirkil, G., Baccioglu, A., Gedik, C., Sahin, Unal, EKİCİ, AYDANUR, Duru, Serap, Ulasli, Sevinc Sarinc, Kurtipek, Ercan, Gunay, Sibel, Dalli, A., Sarioglu, N., Kocak, N. D., Akturk, U. A., Demir, M., Kilic, T., Hezer, H., Altintas, N., Acat, M., Dagli, C. E., Kargi, A., Karadeniz, G., Intepe, Y. S., Onyilmaz, T., Saylan, B., Baslilar, S., Sariman, N., Ozkurt, S., Arinc, S., Kanbay, A., Yazar, E. E., Yildirim, Z., Kadioglu, E. E., Gul, S., Sengul, A., Berk, S., Dikis, O. S., Bahadir, A., Baris, S. A., Ugurlu, A. O., Ilgazli, A. H., Ortakoylu, M. G., Erginel, M. S., Yaman, N., Arslan, Y., Kurt, O. K., Erol, S., Korkmaz, C., Balaban, A., Erbay, Toru U., Sogukpinar, O., Uzaslan, E. K., Babaoglu, E., Fidan, F., Kararmaz, E., Guzel, A., Alzafer, S., Cortuk, M., Hocanli, I, Tanriverdi, H., Yavuz, M. Y., Sertogullarindan, B., Ozyurt, S., Erbaycu, A. E., Demir, A., Duman, D., Kaya, S. B., Ayik, S., Yazici, O., Akgedik, A., Yasar, Z. A., Hayat, E., Kalpaklioglu, F., Demirci, N. Y., Bora, M., Talay, F., Bulcun, E., Yuce, G. D., Sariaydin, M., Ayten, O., Bayraktaroglu, M., Tekgul, S., and BURSAL DURAMAZ, BURCU
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musculoskeletal diseases ,Male ,medicine.medical_specialty ,Birth weight ,Gestational Age ,03 medical and health sciences ,0302 clinical medicine ,Neonatal Screening ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Hip Dislocation, Congenital ,Retrospective Studies ,Ultrasonography ,030222 orthopedics ,Developmental dysplasia ,business.industry ,Obstetrics ,Infant, Newborn ,Gestational age ,Retrospective cohort study ,Early neonatal period ,Duramaz A., BURSAL DURAMAZ B., Bilgili M. G. , -Does gestational age affect ultrasonographic findings of the hip in preterm newborns? A sonographic study of the early neonatal period-, JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B, cilt.28, ss.107-110, 2019 ,Pediatrics, Perinatology and Child Health ,Gestation ,Female ,business ,030217 neurology & neurosurgery ,Infant, Premature - Abstract
There are only a few studies in the literature investigating the effects of gestational age on developmental dysplasia of the hip. The aim of this study was to investigate the effects of gestational age on hip ultrasound findings in the early neonatal period in preterm newborns born between 30th and 36th weeks of gestational age. Between January 2008 and December 2013, a total of 788 hips of 394 premature newborns with a gestational age of up to 36th weeks who underwent hip ultrasonography in the first week of their life were retrospectively examined. The distribution of roof angles and hip types in terms of sexes was compared between groups. Birth weight, birth height, a, and beta angles were analyzed in terms of the gestational age. The mean gestational age was 33.07 weeks (SD 2.09; between 30th and 36th). Six hundred and seven hips were classified as type I, 154 as type IIa, 21 as type IIc, and 6 as type III. In the 30th week, type IIc hips in females and type III hips in males were statistically significantly higher (P=0.001). In the 34th week, type IIc hips in males were statistically significantly higher than the females (P=0.013). In the 35th week, type IIa hips in females hips were statistically significantly higher than the males (P=0.008). Among all preterm infants, type IIc hips were more common in the 30th, 31st, 32nd, and 34th weeks, whereas type III hips were statistically significantly more common in the 30th week (P=0.0001). The 30th, 31st, 32nd, and 34th weeks of age are gestational ages that should be considered in terms of dysplastic and subluxed hips in premature newborns. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.
- Published
- 2018
10. Copeptin Levels in Clinically Silent Multiple Sclerosis
- Author
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İrem İlgezdi, Ufuk Şener, Levent Öcek, Şükran Köse, Alp Sarıteke, Figen Tokuçoğlu, and Yaşar Zorlu
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hypothalamic pituitary adrenal axis ,multiple sclerosis ,copeptin ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: Hypothalamic-pituitary-adrenal (HPA) axis dysfunction is thought to be found in patients with multiple sclerosis (MS). Copeptin is a serum protein that is indicated as an indirect marker of HPA axis. The aim of this study was to evaluate the relationship between HPA axis and clinically silent MS (CSMS) by evaluating copeptin levels. Materials and Methods: Sixty patients with CSMS which was defined as relapsing-remitting MS without attack and progression, and 60 healthy individuals were included in the study from September 2016 to September 2017. All patients were in the remission period. HPA axis dysfunction was examined by measuring serum copeptin levels in all individuals. Copeptin level was compared with clinical parameters in patients with MS. Results: A total of 120 individuals were composed of 60 patients with CSMS and 60 healthy controls. The average ages of the patients and the control group were 37.1+-8 (20-52) and 35.1+-8.9 (18-54), respectively. The copeptin level was significantly lower in patients compared to the control group (p
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- 2022
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11. The influence of carbon source and content on structure and mechanical properties of sic processed via spark plasma sintering method
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Yaşar Zeynep Aygüzer, Delucca Vincent A., and Haber Richard A.
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silicon carbide ,sintering ,spark plasma sintering ,solid state ,microstructure ,Clay industries. Ceramics. Glass ,TP785-869 - Abstract
The effects of carbon sources and carbon content on the density, microstructure, hardness and elastic properties of dense SiC ceramics were investigated. The precursor powders were prepared by adding 1.5-4.5wt.% C (carbon lamp black or phenolic resin) and 0.5 wt.% B4C to SiC and sintered at 1900°C for 15min under 50MPa pressure in argon with an intermediate dwell at 1400°C for 30min. The results showed that carbon lamp black provided better mixing than phenolic resin since carbon cluster was found in the samples made with phenolic resin. Increasing carbon content causes the decrease of 4H polytype amount in the samples. The presence of higher than 1.5wt.% carbon inhibits grain growth and the presence of the 4H polytype. SiC samples can be produced with relative density of more than 99%TD with 1.5wt.% carbon lamp black addition which shows small average grain size, high elastic modulus and hardness of 2.28 μm, 453GPa and 21.2GPa, respectively.
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- 2022
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12. Different modulation schemes for direct and external modulators based on various laser sources
- Author
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El-Hageen, Hazem M., Kuppusamy, P.G., Alatwi, Aadel M., Sivaram, M., Yasar, Z. Ahamed, and Zaki Rashed, Ahmed Nabih
- Abstract
Different types of laser source modulation techniques have been used in various applications depending on the objective. As optical systems extract the laws and the best solutions from experiments and simulations, the present study uses simulation software with different modulation types so the output signals can be compared. The modulators used are Mach-Zehnder, which is an external modulator, and electro-absorption modulator and laser rate equation modulator, which are direct modulators. All these types have an optical link multimode (MM) fiber with a photodiode in the receiver end that can be modeled. The input and output signals are analyzed using different types of modulations.
- Published
- 2021
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- View/download PDF
13. Investigation of the effect of pressure, sintering temperature and time on silicon carbide microstructure
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Yasar Zeynep Ayguzer, DeLucca Vincent A., and Haber Richard A.
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silicon carbide ,spark plasma sintering ,pressure ,sintering temperature ,sintering time ,Clay industries. Ceramics. Glass ,TP785-869 - Abstract
In this research, SiC ceramics were densified via spark plasma sintering (SPS) with 0.5wt.% B4C and 1.5wt.% C additions at temperatures ranging from 1900 to 2000°C for 5-65min under 10-50MPa applied pressure with an intermediate dwell at 1400°C, and the effects of applied pressure, sintering temperature, and dwelling time were examined. The samples sintered under 50MPa applied pressure had high density (>99%), and showed high elastic modulus (~420MPa). However, lower applied pressure caused a decrease in density and elastic properties. The increase of sintering temperature from 1900 to 2000°C, while sintering time and pressure remained the same, caused grains coarsening. Increasing the dwelling time for the samples sintered at 1900 and 2000°C showed that sintering at a relatively lower temperature for a longer period of time did not increase grain size significantly. On the other hand, increasing the dwelling time at 2000°C caused excessive grain growth. The results show that fine-grained highly dense SiC can be produced by spark plasma sintering at 1900°C for 5min under 50MPa.
- Published
- 2022
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14. Is an elevated neutrophil-to-lymphocyte ratio a predictor of metabolic syndrome in patients with chronic obstructive pulmonary disease?
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Yasar Z, Buyuksirin M, Fd, Ucsular, Kargı A, Erdem F, Talay F, and Ok, Kurt
- Subjects
Male ,Metabolic Syndrome ,Pulmonary Disease, Chronic Obstructive ,Neutrophils ,Predictive Value of Tests ,Humans ,Female ,Lymphocytes ,Middle Aged ,Aged ,Retrospective Studies - Abstract
This study aimed to evaluate the diagnostic value of the neutrophil-to-lymphocyte ratio (NLR) in early detection of metabolic syndrome (MetS) in patients with chronic obstructive pulmonary disease (COPD).We retrospectively enrolled hospital records of 140 COPD patients and 50 sex and age-matched healthy controls. The diagnostic values of NLR were estimated using the sensitivity, specificity, and area under the receiver operating characteristic curve (AUC).In total, 140 patients with COPD of which 63 patients had MetS and 50 healthy subjects were included in the study. We found that the NLR values of the stable COPD patients were significantly higher than those of the controls (p0.001). Among patients with COPD, the NLR was significantly higher in patients with than without MetS (p0.001). The AUC of the NLR was 0.898 in patients with MetS. The optimal NLR cut-off was 2.56 and was validated in the testing set. For evaluation of MetS, the sensitivity and specificity were 84.1% and 84.4% in patients with COPD under the suggested cut-offs.The NLR is a simple, effective, and practical predictor of MetS in patients with stable COPD. It has potential value in public health practice for management of patients with COPD.
- Published
- 2015
15. Association Between Interleukin 1 Beta (IL-1β) Gene Variation and Temporal Lobe Epilepsy with Hippocampal Sclerosis
- Author
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Alp Sarıteke, İrem Fatma Uludağ, Berk Özyılmaz, Yaşar Zorlu, Ufuk Şener, and Figen Tokuçoğlu
- Subjects
il-1beta ,temporal lobe epilepsy ,hippocampal sclerosis ,epilepsy ,genetics ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: We aimed to determine the association between a polymorphism in the promoter region of the IL-1beta gene resulting in enhanced gene transcription and the clinical phenotype of temporal lobe epilepsy with hippocampal sclerosis (TLE+HS). Materials and Methods: The frequency of a single nucleotide polymorphism (SNP) that results in a C>T transition of 511 base pairs that are five prime to the transcription start site of the IL-1beta gene in a group of 21 patients with TLE+HS, 21 patients with temporal lobe epilepsy without hippocampal sclerosis (TLE-HS), and 23 healthy volunteers. Results: The frequency of the -511T allele was 11/21 in the TLE-HS group, 13/21 in the TLE+HS group, and 12/23 in the control group. Chi-square analysis of genotype and allele distribution showed no significant difference between the patients in TLE+HS, TLE-HS, and control group Conclusion: There was no association between the -511/C>T SNP variation and TLE+HS.
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- 2021
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16. Effects of quercetin on kidney injury induced by doxorubicin
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Yagmurca, M., primary, Yasar, Z., additional, and Bas, O., additional
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- 2015
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17. Use of Pyracantha coccinea Roem. as a possible biomonitor for the selected heavy metals
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N. Akguc,I. I. Ozyigit,U. Yasar,Z. Leblebici,C. Yarci
- Published
- 2010
18. THE RELATIONSHIP BONE MINERAL DENSITY AND HIGH-DOSE SHORT-TERM CORTICOSTEROID THERAPY IN MULTIPLE SCLEROSIS PATIENTS
- Author
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Pinar Bekdik Sirinocak, Neslihan Eskut, Ufuk Sener, and Yasar Zorlu
- Subjects
multiple sclerosis ,bone mineral density ,vitamin d ,Medicine (General) ,R5-920 - Abstract
Introduction: Previous studies were reported that osteoporosis and bone fracture occurs more frequently among Multiple sclerosis patients than the general population. The aim of this study to investigate the affects of total doses of short-term, high dose corticosteroids on bone mineral density and other affecting factors for bone mineral density in Relapsing-remitting type Multiple Sclerosis patients. Material and methods: Fifty-four patients (37 females, 17 males) with relapsing-remitting type Multiple Sclerosis who filled the diagnostic criteria according to McDonald criteria were included in the study. Femoral and lumbar bone mineral density were measured using dual energy X-ray absorptiometry. Expanded Disability Status Scale, disease duration, number of attacks, cumulative corticosteroid dose were recorded. Serum calcium, potassium, phosphorus, vitamin D, parathormone and osteocalcin levels were measured. Patients were divided into two groups: patients who have received at least 20 g intravenous metilprednisolone (Group I) and patients who have received less than 20 g intravenous metilprednisolone (Group II). We analysed association between cumulative corticosteroid dose and each parameters. Results: Osteopenia was present in 46.2% and osteoporosis in 5.5% of the study population according to femoral neck bone mineral density. Femoral bone mineral density was significantly lower among patients. There was no correlation between cumulative dose of corticosteroid and bone mineral density. Conclusion: Low bone mineral density and osteoporosis are common in Multiple sclerosis patients. High-dose steroid therapy is not be the primary cause of osteoporosis in patients with multiple sclerosis.
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- 2020
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19. Seltene Ursache rechtsseitiger Oberbauchschmerzen
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Händl, T, primary, Kreil, C, additional, Yasar, Z, additional, and Wehler, M, additional
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- 2014
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20. Muscle mass, strength, and physical performance predicting activities of daily living: a meta‐analysis
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Daniel X.M. Wang, Jessica Yao, Yasar Zirek, Esmee M. Reijnierse, and Andrea B. Maier
- Subjects
Muscle mass ,Muscle strength ,Handgrip strength ,Physical performance ,Activities of daily living ,Aged ,Diseases of the musculoskeletal system ,RC925-935 ,Human anatomy ,QM1-695 - Abstract
Abstract Background Activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are essential for independent living and are predictors of morbidity and mortality in older populations. Older adults who are dependent in ADLs and IADLs are also more likely to have poor muscle measures defined as low muscle mass, muscle strength, and physical performance, which further limit their ability to perform activities. The aim of this systematic review and meta‐analysis was to determine if muscle measures are predictive of ADL and IADL in older populations. Methods A systematic search was conducted using four databases (MEDLINE, EMBASE, Cochrane, and CINAHL) from date of inception to 7 June 2018. Longitudinal cohorts were included that reported baseline muscle measures defined by muscle mass, muscle strength, and physical performance in conjunction with prospective ADL or IADL in participants aged 65 years and older at follow‐up. Meta‐analyses were conducted using a random effect model. Results Of the 7760 articles screened, 83 articles were included for the systematic review and involved a total of 108 428 (54.8% female) participants with a follow‐up duration ranging from 11 days to 25 years. Low muscle mass was positively associated with ADL dependency in 5/9 articles and 5/5 for IADL dependency. Low muscle strength was associated with ADL dependency in 22/34 articles and IADL dependency in 8/9 articles. Low physical performance was associated with ADL dependency in 37/49 articles and with IADL dependency in 9/11 articles. Forty‐five articles were pooled into the meta‐analyses, 36 reported ADL, 11 reported IADL, and 2 reported ADL and IADL as a composite outcome. Low muscle mass was associated with worsening ADL (pooled odds ratio (95% confidence interval) 3.19 (1.29–7.92)) and worsening IADL (1.28 (1.02–1.61)). Low handgrip strength was associated with both worsening ADL and IADL (1.51 (1.34–1.70); 1.59 (1.04–2.31) respectively). Low scores on the short physical performance battery and gait speed were associated with worsening ADL (3.49 (2.47–4.92); 2.33 (1.58–3.44) respectively) and IADL (3.09 (1.06–8.98); 1.93 (1.69–2.21) respectively). Low one leg balance (2.74 (1.31–5.72)), timed up and go (3.41 (1.86–6.28)), and chair stand test time (1.90 (1.63–2.21)) were associated with worsening ADL. Conclusions Muscle measures at baseline are predictors of future ADL and IADL dependence in the older adult population.
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- 2020
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21. The significance of Holter electrocardiography in the etiological evaluation of transient ischemic stroke
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Yıldız Arslan, Burcu Selbest Demirtaş, Cenk Ekmekci, Figen Tokuçoğlu, and Yaşar Zorlu
- Subjects
holter electrocardiography ,transient ischemic attacks ,undetermined source ,Medical technology ,R855-855.5 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BACKGROUND: Transient ischemic attack (TIA) is a common neurovascular disorder associated with a higher risk of stroke within the first 24 h after the first event. Acute cerebral and arterial neuroimaging combined with long-term electrocardiography (ECG) monitoring have been proven to be useful in determining etiology. Cardio-embolism constitutes 20%–26% etiology of TIAs most of them with atrial fibrillation (AF). Investigation of AF after TIA is very important because oral anticoagulants can reduce the risk of subsequent stroke by two thirds. MATERIALS AND METHODS: The present study included 45 patients suffering from TIA with undetermined source according to the Trial of Org 10172 in Acute Stroke Treatment criteria; the control group (n = 45) was selected from the patients admitted to cardiology outpatient clinic with nonspecific complaints without cerebrovascular and/or cardiovascular disease. All patients underwent echocardiography and 24 h Holter ECG monitoring (HM). RESULTS: There was no significant difference between the patient group and the control group in terms of age and gender. Cholesterol, low-density lipoprotein and urea levels, left atrium diameters and the incidence of hypertension, coronary artery diseases, and AF were significantly higher in TIA group (P < 0.05). In the results of HM, there were six patients with AF in the study group, and in the control group, there was no patients with AF (P = 0.03). DISCUSSION AND CONCLUSION: In acute phase of TIA, 24 h HM is important for determining the etiology and selecting an appropriate treatment that can protect patients from subsequent strokes.
- Published
- 2020
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22. Food and non-food factors affecting nutrition provision in care homes in Surrey
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Omar, N., primary, Varley, J., additional, Yasar, Z., additional, Garland, S., additional, Hart, K., additional, Engel, B., additional, and Gibbs, M., additional
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- 2010
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23. Electrocardiographic Changes and Their Prognostic Effect in Patients with Acute Ischemic Stroke without Cardiac Etiology
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Aydın Kaya, Yıldız Arslan, Öner Özdoğan, Figen Tokuçoğlu, Ufuk Şener, and Yaşar Zorlu
- Subjects
Acute ischemic stroke ,ECG changes ,TnI levels ,stroke prognosis ,cerebellar infarcts ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: Acute ischemic stroke has an effect on electrocardiography (ECG) results and cardiac enzyme levels, but its mechanism has not been clearly established. Our aim was to research ECG and cardiac enzyme changes in acute ischemic stroke and to investigate the association between these changes and stroke localizations and prognosis. Materials and Methods: The study included 241 patients with acute ischemic stroke. Patients without cardiac arrhythmia, history of previous stroke, use of drugs affecting the pattern and duration of ECG rhythm and without acute or chronic myocardial infarction history and electrolyte imbalance were included. The vascular risk factors for stroke, creatine kinase-MB (CK-MB), and troponin I (TnI) levels, and ECG results were examined. Results: One hundred twenty-three patients had right hemisphere infarcts and 118 patients had left hemisphere infarcts with the same mean ages. HT was more prevalent in right hemisphere infarcts (p=0.013). The most common ECG abnormalities were QTc prolongation (31%) and ST depression (24%). CK-MB and TnI levels were significantly higher in patients with right hemispheric and cerebellar infarcts. QRS durations were longer in cerebellar infarcts (p=0.05). Conclusion: The most common ECG abnormality was QTc prolongation in patients with acute ischemic stroke within 24 hours. CK-MB and TnI levels were higher in patients with right hemisphere and cerebellar infarcts.
- Published
- 2018
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24. Significance of multiple acute ischemic lesions on initial diffusion-weighted imaging in stroke patients and relation of toast classification
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Ufuk Sener, Levent Ocek, Irem Ilgezdi, Hilal Sahin, Murat Ozcelik, and Yasar Zorlu
- Subjects
Acute ischemic stroke ,diffusion-weighted imaging ,multiple vascular territory ,single vascular territory ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Background: It is important to know whether or not the stroke risk factors and etiologies of patients with multiple acute infarcts are different to those of patients with a single acute infarct. Aim: The frequency of multiple acute infarct was investigated in ischemic stroke patients and a comparison was made of the characteristics of stroke patients with and without multiple acute infarct. Patients and Methods: We reviewed the clinical records of 988 ischemic stroke patients who were admitted within 1 week of the onset of stroke and diffusion-weighted imaging (DWI) was performed on first presentation. The clinical characteristics, laboratory, and imaging results were noted from the patient records. According to the DWI findings, the patients were separated into three groups as those with a single acute infarct in a single vascular territory (SI group), those with multiple acute infarcts in a single vascular territory (SMI group) and those with multiple acute infarcts in multiple vascular (MMI group) territories. The frequency of multiple acute infarcts was investigated, and a comparison was made of the characteristics of stroke patients with and without multiple acute infarcts. Results: The SMI group included 119 (12%) patients and the MMI group 126 (12.8%). The most common mechanisms of multiple acute infarcts are large artery atherosclerosis and cardiac origin emboli. Moreover, the risk factors most determined were hypertension, diabetes mellitus, and hyperlipidemia in the MMI group. Conclusion: No difference was determined between the groups in respect of stroke etiology and risk factors.
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- 2018
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25. Haemoperfusion in Amanita phalloides Poisoning
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Aji, D. Y., primary, Caliskan, S., additional, Nayir, A., additional, Mat, A., additional, Can, B., additional, Yasar, Z., additional, Ozsahin, H., additional, Cullu, F., additional, and Sever, L., additional
- Published
- 1995
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26. The relation between cervical and thoracal disc herniations and multiple sclerosis plaques: a retrospective review
- Author
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Ozgul Ocak, Mustafa Cetiner, Yasar Zorlu, Ufuk Sener, and Murat Uygur
- Subjects
Multiple Sclerosis ,cervical disc herniations ,thoracal disc herniations ,spinal cord compression ,Medicine - Abstract
The aim of the study is the evaluation cervical and thoracal disc herniations are predisposant factor to the formation and activation of plaques formation of relapsing remitting (R-R ) type multiple sclerosis (MS) patients. We performed a retrospective study on R-R type MS diagnosed patients who also had cervical and thoracal disc herniations. 185 cervical and 136 thoracic in total 321 MR images of 104 (42 men, 62 women) MS patients with R-R type were evaluated retrogradly. When we evaluate the association between cervical or thoracal disc herniation and MS plaques we determined the same localization of cervical herniation and MS plaques was statistically significant. In conclusion, cervical and thoracic disc herniations may contribute to distrupion of blood brain barrier by generating microtraumas and this may lead to MS plaque formation. Therefore, early and effective treatment of MS patients having disc compression is crucial for preventing from sequels and for providing a better life quality. [Med-Science 2017; 6(4.000): 643-645]
- Published
- 2017
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27. Correlation of Electromyography and Magnetic Resonance Imaging Findings in the Diagnosis of Suspected Radiculopathy
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Yıldız Arslan, Ebru Yaşar, and Yaşar Zorlu
- Subjects
Suspected radiculopathy ,electromyography ,magnetic resonance imaging ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
INTRODUCTION: Patients with pain or numbness without motor deficits are the most common group referred to electrophysiology laboratories as suspected radiculopathy. We wanted to investigate whether electromyography (EMG) was useful for this group in the diagnosis or therapy of radiculopathy. Our aim was to investigate the correlation and classification of EMG and magnetic resonance imaging (MRI) findings in the diagnosis of suspected radiculopathy. METHODS: We included 74 patients with a ≥2-month history of numbness and pain in the neck and back that radiated into the arm or leg. Patients with diabetes mellitus, previous disc or spine operation, polyneuropathy, spinal cord diseases (tumor, infection or syrinxs), motor deficits, and abnormal nerve conduction studies were excluded. RESULTS: The mean age of the patients was 51.58±11.53 years. In total, 41 (55.4%) patients were women and 33 (44.6%) were men; 48.8% (n=36) showed cervical radiculopathy and 51.2% (n=38) exhibited lumbosacral radiculopathy. The most common MRI finding was protrusion (37.8%), and the most common EMG finding was re-innervation (59.5%). The correlation of MRI and EMG findings was significant in lumbar radiculopathy (p=0.007), but not in the cervical radiculopathy results (p=0.976). DISCUSSION AND CONCLUSION: EMG and MRI findings were compatible for lumbar radiculopathy, but not for cervical radiculopathy in mild to moderate grades.
- Published
- 2016
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28. Epilepsi Hastalarında Lamotrijin Deneyimi
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Levent ÖCEK, İrem Fatma ULUDAĞ, Derya GÜNER, and Yaşar ZORLU
- Subjects
effects and side effects ,epilepsy ,lamotrigine ,Neurology. Diseases of the nervous system ,RC346-429 ,Medicine - Abstract
Objectives:The aim of the present study was to investigate the effect and side effects of lamotrigine (LTG) on seizures.Methods:Epilepsy outpatient clinic records for 416 patients who had been monitored for at least 6 months were studied retrospectively. Age, sex, seizure type, number of seizures, additional drugs used in treatment, duration of treatment, and drug side effects were analyzed.Results:Of the 416 patients, 244 (58.7%) were female, and 162 were male (41.3%). Mean age was 33.2±10.7. Monthly seizure rates were reduced 67.3% with LTG treatment, and 328 patients (78.8%) were still receiving treatment, while 88 (21.2%) had stopped usage due to side effects or for other reasons. Of these side effects, dizziness (5.5%) and rash (4.3%) were the most common. Pregnancy occurred in 18 patients on LTG treatment, and no malformation was detected at birth.Conclusion:In refractory epileptic patients, LTG has a high activity level and an acceptable side effect profile.
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- 2015
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29. A Rare Cause of Superficial Cerebral Hemosiderosis: Spinal Surgery
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Levent Öcek, Feray Güleç Uyaroğlu, Ali Çayır, Özgür Öztekin, and Yaşar Zorlu
- Subjects
Superficial hemosiderosis ,spinal tumor operation ,magnetic resonance imaging ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2017
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30. TÜRKİYE’DE BİR POPÜLER KÜLTÜR ARACI OLARAK TELEVİZYON
- Author
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Yaşar Zorlu
- Subjects
popüler kültür ,televizyon ,toplum ,tüketim ,kitle i̇letişim araçları ,Journalism. The periodical press, etc. ,PN4699-5650 - Abstract
Kitle iletişim araçlarının yaygınlaşmasıyla birlikte kültürel dönüşümün hız kazanması, kitle iletişim araçları ve popüler kültür arasında karşılıklı beslenmeye dayanan bir ilişkiye zemin hazırlamıştır. Kitle iletişim araçları ve popüler kültür arasındaki ilişkinin arkasında popüler kültür ürünlerinden ekonomik kâr elde etmek isteyen büyük sermaye grupları bulunmaktadır. Temelde ekonomik sebeplere dayanan ilişkiler ağı, toplumsal etkileri açısından kültürel bir boyut kazanmaktadır. Kültürel boyutu, büyük ölçüde en popüler bir iletişim aracı olan televizyon içerikleri ile ilintilidir. Popüler kültürün lokomotifi televizyon, ürettiği ve sunduğu içerikleriyle, popüler kültürün oluşumunda ve sürdürülmesinde önemli bir etkendir. Dünyada olduğu gibi Türkiye’de de televizyon, magazin programları, diziler, reklamlar gibi sunduğu içeriklerle popüler kültürü sürdüren, destekleyen, yenileyen özellikleriyle toplumsal yaşamı dönüştürücü bir nitelik taşımaktadır.
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- 2016
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31. Aceruloplasminemia Presenting with Cognitive Impairment
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Yıldız Arslan, Ufuk Şener, Alp Sarıteke, and Yaşar Zorlu
- Subjects
Aceruloplasminemia ,cognitive impairment ,iron accumulation ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2017
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32. Late-onset Tremor and Ataxia Syndrome: Fragile X-Associated Tremor/Ataxia Syndrome and Neuroimaging Findings
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Levent Öcek, Onural Tümer, Figen Tokuçoğlu, Özgür Öztekin, and Yaşar Zorlu
- Subjects
Fragile X-associated tremor/ataxia syndrome ,premutation ,magnetic resonance imaging. ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2017
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33. Pre-operative Evaluation in Patients with Neurological Diseases, Part 2
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İrem Fatma Uludağ, Muhteşem Gedizlioğlu, and Yaşar Zorlu
- Subjects
Preoperative period ,neurology ,surgery ,disease management ,perioperative period ,anesthetics ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Neurologic diseases influence the morbidity and mortality in non-neurosurgical operations and determine the required tests for the preoperative evaluation, the choice of the anesthetic medication and the perioperative care. The present review provides information about the principles of the preoperative management in patients with neurologic diseases undergoing non-neurosurgical operations and addresses some special preoperative management issues in specific neurological diseases.
- Published
- 2011
34. Pre-operative Evaluation in Patients with Neurological Diseases, Part 1
- Author
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İrem Fatma Uludağ, Muhteşem Gedizlioğlu, and Yaşar Zorlu
- Subjects
Preoperative period ,neurology ,surgery ,disease management ,perioperative period ,anesthetics ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Neurologic diseases influence the morbidity and mortality in non-neurosurgical operations and determine the required tests for the preoperative evaluation, the choice of the anesthetic medication and the perioperative care. The present review provides information about the principles of the preoperative management in patients with neurologic diseases undergoing non-neurosurgical operations and addresses some special preoperative management issues in specific neurological diseases
- Published
- 2011
35. Neurobrucellosis Presenting As Leukoencephalopathy and Deafness
- Author
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Feray Güleç, Hasan Armağan Uysal, and Yaşar Zorlu
- Subjects
Neurobrucellosis ,leukoencephalopathy ,deafness ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Neurological involvement of the central nervous system in brucellosis is uncommon. Sensorineural hearing loss is a rare complication of neurobrucellosis, which has not attracted enough attention among known manifestations. A 50-year-old man presented with headache, deafness and deteriorated in cognitive functions. The presence of diffuse white matter changes on brain magnetic resonance imaging (MRI) and serum and cerebrospinal fluid findings led to the diagnosis of neurobrucellosis. The differential diagnosis of diffuse white matter diseases is constantly expanding. In the background of fever, deafness, demential symptoms, cognitive impairment and extensive white matter disease, neurobrucelosis should be considered.
- Published
- 2011
36. Serum Leptin Levels in Epileptic Patients Treated with Topiramate and Valproic Acid
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İrem Fatma Uludağ, Ufuk Şener, Yaşar Zorlu, Mehmet Hicri Köseoğlu, and Tuğba Kantaroğlu Aydın
- Subjects
Leptin ,valproic acid ,topiramate ,obesity ,epilepsy ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: Leptin is considered to be a signal factor that regulates body weight and energy expenditure, and there is a strong correlation between serum leptin concentrations, body mass index, and body fat mass in humans. Our aim in this study was to evaluate the role of leptin in valproic acid (VPA) and topiramate (TPM) related weight changes in epileptic patients. METHODS: Body mass index is calculated and serum leptin and insulin levels are measured in 56 patients with epilepsy (40 patients taking VPA and 16 patients taking VPA and TPM) and in 40 healty control subjects. RESULTS: Obesity was seen in 21 patients (52.5%) in VPA treated group, in 15 patients (37.5%) in the control group and in only one male (6.3%) in VPA and TPM treated group. Body mass index was lower in the group treated with VPA and TPM (p
- Published
- 2011
37. The Relation Between the Infarct Volume and Carotis Intima-Media Thickness in Acute Stroke
- Author
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Melike Yıldırım, Fuat Şahin, Ufuk Şener, Yaşar Zorlu, and İrem Fatma Uludağ
- Subjects
Stroke ,carotid arteries ,cerebral infarction ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: In this study, it was aimed to determine the relation between the cerebral infarction volume and common carotid artery (CCA) intima-media thickness (IMT) and internal carotid artery (ICA) intima-media thickness. METHODS: Forty patients diagnosed with acute ischemic stroke and admitted to our clinic within the first 24 hours were accepted into this study. The brain computed tomographies taken at admission and 72 hours after the onset of the first symptoms were analyzed. The volume of the infarct areas was measured. The bilateral carotis (C) IMT was measured by Doppler ultrasonography. RESULTS: CCA IMT was significantly thicker in the group with single plaque compared to the group without plaque. CONCLUSION: No statistically significant relation between the infarct volume and ICA IMT or CCA IMT was observed.
- Published
- 2010
38. The Effect of Mannitol Treatment on Renal Functions in Acute Stroke
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Neslihan Eşkut, Çağla Filiz, Ufuk Şener, Metin Murat Özçelik, Nazif Çalış, and Yaşar Zorlu
- Subjects
Mannitol ,stroke ,urea ,creatinine ,electrolytes ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: Mannitol is an osmotic diuretic agent and reduces intracranial pressure. The most serious side effect of mannitol is kidney dysfunction. In this study, renal functions in acute stroke patients treated with mannitol were evaluated. METHODS: One hundred and twenty-two patients followed in the neurology intensive care unit with the diagnosis of stroke and treated with fractionated mannitol for 5 days were evaluated retrospectively. Ninety-six patients had ischemic and 26 had hemorrhagic stroke. Mean age was 69.9 ± 11.8 (18-91) years. Serum urea, creatinine and electrolyte levels measured before and on the second, third, fourth, fifth and tenth days of treatment were compared statistically with paired sample t test. RESULTS: The average urea and creatinine levels on the second, third, fourth and fifth days of treatment were significantly higher than the baseline (p< 0.05). On the other hand, mannitol treatment did not change average sodium, potassium and chlorine levels. The creatinine levels had returned to the normal range on the tenth day of treatment, but the urea levels, although decreased, did not fall to the normal range. CONCLUSION: Our results support the view that close monitoring of renal function is necessary in patients treated with mannitol.
- Published
- 2010
39. Multiple Cranial Nerve Involvement Caused By Herpes Zoster Oticus Infection
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İrem Fatma Uludağ, Nilüfer Yıldırım, Ufuk Şener, and Yaşar Zorlu
- Subjects
Herpes zoster oticus ,cranial nerve diseases ,ophthalmoplegia ,Ramsay Hunt auricular syndrome ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Varicella zoster infection is an important cause of cranial neuropathy. In Ramsay Hunt syndrome caused by herpes zoster oticus, the involvement of the vestibulocochlear nerve can be seen with peripheral facial palsy, but the involvement of the other cranial nerves is not frequent. A 59-years-old male patient referred to our clinic with diplopia, deafness, dysphagia, and hoarseness after herpes zoster oticus infection. In neurologic examination there was revealed 6th, 7th, 8th, 9th, and 10th cranial nerve involvement on the left. On imaging and laboratory studies, there was no other pathology other than herpes zoster oticus infection to explain the multiple cranial nerve involvement. Our case is one of the very rare cases of multiple cranial nerve involvement due to herpes zoster oticus infection
- Published
- 2009
40. General Approach to Diagnosis and Treatment of Multiple Sclerosis in Turkey
- Author
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Murat Terzi, Yahya Çelik, Münire Kılınç, Feray Seleker, Nihal Işık, Muhteşem Gedizlioğlu, and Yaşar Zorlu
- Subjects
Multiple sclerosis ,diagnosis ,therapy ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: The clinical progress of multiple sclerosis (MS), initial symptoms and problems during the course of a disease that can be seen, may vary among the patients. Therefore, different applications occurs in the disease diagnosis and treatment plan. The difficulties of diagnosis, treatment and progress of MS disease, experienced by the neurology residents and experts from different regions of the Turkey is intended to introduce. METHODS: Interactive meetings was arrenged in total 11 cities from different regions of Turkey, between March 2008 and June 2008. The data obtained as a result of the responses of participants were evaluated. RESULTS: Neurology specialist and research assistant, total of 242 persons participated. It was observed that 14 percent of visual evoked potential, 40 percent of cerebrospinal fluid (CSF) oligoclonal band review and one percent of magnetic resonance imaging examinations used in diagnosis of MS can’t be done. There was significant differences between regions about feasibility of CSF OCB. Sixty one percent of participants thought to start immunomodulatory treatment to typical relapsing-remitting multiple sclerosis patients, filled in the Mc Donald diagnostic criteria and had two attack story. CONCLUSION: As all the world, in Turkey being very much difference about clinical, radiological and laboratory features of MS lead to the neurology experts work hard and the emergence of different applications about the disease diagnosis and treatment plan
- Published
- 2009
41. Van der Knaap Leukoencephalopathy Case Report
- Author
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Çağla Soysüren, Ufuk Şener, Süleyman Men, Uğur Kulu, and Yaşar Zorlu
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leukoencephalopathy ,macrocephaly ,ataxia ,subcortical cysts ,adult patient ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Scientific BACKGROUND: Van der Knaap leukoencephalopathy, also known as megalencephalic leukoencephalopathy with subcortical cysts, is a rare form of leukoencephalopathy, which was first described in 1995. It is characterized by early-onset macrocephaly, with mild motor developmental delay and seizures; gradual onset of ataxia, spasticity, and sometimes extrapyramidal findings; and usually late onset of mild mental deterioration. MRI characteristics included diffuse abnormality in signal intensity and swelling of cerebral hemispheral white matter with cyst-like spaces in the frontoparetal and anterior-temporal subcortical areas. CASE: The patient who had no compliants until 20 years old was admitted to our clinic with refractory seizures that continued for six years. Van Der Knaap leucoencephalopathy was considered after the examination. CONCLUSION: This paper, accompanied by cases in literature, is about a patient with Van Der Knaap leucoencephalopathy who had typical clinical and MRI findings
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- 2008
42. Prognostic Value of Electrophysiological Tests in Bell’s Palsy
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Melike Tavşan, Oğuz Karagüzel, Ufuk Şener, Yaşar Zorlu, and Murat Özçelik
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Bell’s palsy ,electromyography ,blink reflex ,facial nerve ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: Bell’s palsy (BP) is the most common disease of the facial nerve. It is acute paralysis of the mimic muscles. The etiology and treatment of BP is not clear. As it is an aesthetic and functional problem, early prognostic diagnosis is more important. Electrophysiologic tests can be used for this purpose METHODS: 46 patients were included to the study. All patients were classified according to House-Brackman system. Facial nerve conduction and blink reflex were studied on 10-12th day of the onset of the BP. RESULTS: The patients who had increase of muscle response (M-response) latency on 10-12th day, had less recovery after one month. There was also no statistical difference between R1 latency on 10-12th day and clinical grade in first month. But there was significant difference between R2 latency on 10-12th day and clinical grade in first month. CONCLUSION: Prolonge of M-response latency and the absence of blink reflex showed poor prognosis
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- 2007
43. HLA and Acetylcholine Receptor Antibody Relationship in Myastenia Gravis Patients
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İrem Fatma Aşan, Ufuk Şener, Pınar Bekdik, Işıl Çoker, and Yaşar Zorlu
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Myasthenia gravis ,HLA ,acetylcholine receptor antibody ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: Autoantibodies against the muscle acetylcholine receptor (AChR) play an essential role in the pathophysiology of autoimmune myasthenia gravis (MG). It is believed that the human leukocyte antigen (HLA) class II molecules are involved in the antibody production in MG because these molecules regulate immune responses to protein antigens by presenting antigenic peptides to CD4 helper T cells, which control the production of antibodies. OBJECTIVE: The aim of the present study was to examine the relationship between HLA haplotypes and AChR antibody in patients with myasthenia gravis. METHODS: A total of 40 (22 female, 18 male) patients with MG were enrolled onto the study and underwent HLA typing and AChR antibody levels. The mean age was 45.4±16 years. The statistical analysis was performed by χ2 test with Yates’ correction to test the presence of an association. RESULTS: The presence of AChR antibodies was significantly associated with HLA CW6 (p0.05). CONCLUSION: Our study demonstrates that the HLA CW6 and HLA B8 haplotypes have significant effects on AChR antibody production on myasthenia gravis patients and that further investigations with large population are required
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- 2007
44. PHYSICO-CHEMICAL AND BIOLOGICAL ACTIVITY OF HAWTHORN (Crataegus spp. L.) FRUITS IN TURKEY
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Sezai Ercisli, Makbule Yanar, Memnune Sengul, Hilal Yildiz, Elif Feyza Topdas, Tuncer Taskin, Yasar Zengin, and Kadir Ugurtan Yilmaz
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Hawthorn ,Crataegus spp. ,biochemical diversity ,genotypic variation ,fruit mass ,anthocyanin ,Biochemistry ,QD415-436 ,Plant culture ,SB1-1110 ,Science - Abstract
Hawthorn (Crataegus spp. L.) is a native fruit of great economic importance in Turkey and has been widely using in folk medicine particularly for the treatment of mild heart diseases for a long time. In the study, 18 previously selected hawthorn genotypes belong to several Crataegus species grown in the hawthorn repository collection in Malatya province in Turkey were evaluated. Fruit mass and soluble solid content of selected genotypes ranged from 0.76 to 4.27 g and 6.71 to 15.83%, respectively. The genotype 44MA12 belongs to C. monogyna subsp. azarella had distinct and the highest anthocyanin (516 mg per 100 g fresh fruit) content and the strongest 1,1-diphenyl-2-picrylhydrazyl radical scavenging capacity (2.91 μg·g-1). The genotype 44MA11 belongs to C. meyeri had the highest phenolic content (3460 mg per 100 g gallic acid equivalent in fresh fruits). All hawthorn genotypes displayed high antioxidant activity. The results suggest that hawthorn fruits including significant human health benefit substances and may be used for developing functional foods because of its high phenolic, anthocyanin content and antioxidant properties.
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- 2015
45. Does Pons Plaque Affect Urination and Urodynamic Functions in Multiple Sclerosis?
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Ural Hamurcu, Nalan Soyder Kuş, Yaşar Zorlu, Ferruh Zorlu, and Oğuz Mertoğlu
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multiple sclerosis ,urodynamic function ,pons ,urologic symptoms ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: More than %80 of Multiple Sclerosis (MS) patients are observed to have urinary system dysfunctions during the course of their ilnesses. Neuronal control of the bladder is highly complicated. Autonomic and somatic nerve systems have to function in coordination. It is known that bladder functions are controlled by medial frontal lobe in the cerebral hemispheres and by pontine reticular formation in the brainstem. A i m: In MS, the relationship between the localization of the plaque and bladder dysfunction is not clear. The aim of this study was to identify the effects of the plaque in pons on the clinical and urodynamic findings by comparing the patients having periventricular and pontine plaques and the ones having only periventricular plaque METHODS: Between May 2001 to June 2003,25 MS patients of whom 15 were females and 10 males studied. The mean age of the patients was 44, while the mean disease duration was 57.2 month. Mean EDSS was 1.82(0-3). The patients were divied into two groupes. Group I (12 cases) consisted of those having periventricular and pons plaque, whereas Group II (13 cases) consisted of those having only periventricular plaque. All patients who had spinal cord plaque excluded. Urodynamic evaluation were done. RESULTS: Comparing the plaque localization and the urodynamic results did not reveal any statistical difference between the groups (p=0.841). The symptoms observed in the groups were studied with respect to their relation with the urdynamic findings. All the symptomatic cases in Group I and half of the symptomatic cases in Group II had abnormal urodynamic findings. Among the asymptomatic cases, %71.4 of Group I and %40 of Group II had normal urodynamic findings. CONCLUSION: As a result, existance of pontine plaque in those having periventricular plaque does not affect the urologic symptoms and urodynamic functions
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- 2006
46. Effects of Antidepressant Treatment on Fatigue in MS Patients with Depression and Fatigue
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Nalan Soyder Kuş, Yaşar Zorlu, Ümit Zanapalıoğlu, Murat Özçelik, Duygu Akarsu, and Nurdan Ökten
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multiple sclerosis ,fatigue ,depression ,antidepressant treatment ,pathophysiology ,Medicine ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
OBJECTIVE: Fatigue and depression are frequently observed symptoms in Multiple Sclerosis (MS). Fatigue has been reported as the major symptom in 53-90% of MS patients. Lifetime incidence of depression has been found as 50% in MS cases. METHODS: There are several studies reporting a positive correlation between depression and fatigue in MS. It has been reported that depression increases the severity of fatigue in these patients. The objective of this study is to evaluate the effects of antidepressant treatment in MS patients having depression and fatigue. RESULTS: 36 cases with definite relapsing-remitting MS (RRMS) who had been free of attacks and steroids for six months were included in this study. Patients, whose examination revealed depression and fatigue, were diagnosed with depression by a psychiatrist. Cases were administered antidepressants and followed by 6 months. The efficacy of the treatment was calculated by Hamilton Depression Rating The decrease in depression and fatigue scores at the end of 3rd and 6th months were found to be statistically significant. (p0.05). CONCLUSION: A partial improvement can be obtained in fatigue by antidepressant treatment
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- 2006
47. Peak Power Output Is Similarly Recovered After Three- and Five-Days’ Rest Following Sprint Interval Training in Young and Older Adults
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Yasar, Z., Dewhurst, S., Hayes, L., Yasar, Z., Dewhurst, S., and Hayes, L.
- Abstract
(1) Background: High-intensity interval training (HIIT) exerts effects indicative of improved health in young and older populations. However, prescribing analogous training programmes is inappropriate, as recovery from HIIT is different between young and older individuals. Sprint interval training (SIT) is a derivative of HIIT but with shorter, maximal effort intervals. Prior to prescribing this mode of training, it is imperative to understand the recovery period to prevent residual fatigue affecting subsequent adaptations. (2) Methods: Nine older (6M/3F; mean age of 70 ± 8 years) and nine young (6M/3F; mean age of 24 ± 3 years) participants performed a baseline peak power output (PPO) test. Subsequently, two SIT sessions consisting of three repetitions of 20 s ‘all-out’ stationary cycling bouts interspersed by 3 minutes of self-paced recovery were performed. SIT sessions were followed by 3 days’ rest and 5 days’ rest on two separate occasions, in a randomised crossover design. PPO was measured again to determine whether recovery had been achieved after 3 days or after 5 days. (3) Results: Two-way repeated measure (age (older, young) × 3 time (baseline, 3 days, 5 days)) ANOVA revealed a large effect of age (p = 0.002, n2p = 0.460), with older participants having a lower PPO compared to young participants. A small effect of time (p = 0.702, n2p = 0.022), and a medium interaction between age and time (p = 0.098, n2p = 0.135) was observed. (4) Conclusions: This study demonstrates both young and older adults recover PPO following 3 and 5 days’ rest. As such, both groups could undertake SIT following three days of rest, without a reduction in PPO. View Full-Text
48. Tongue myokymia presenting twelve years after radiation therapy
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Bedile Irem Tiftikcioglu, Ismail Bulbul, Metin Murat Ozcelik, Gonul Piskin-Demir, and Yasar Zorlu
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Objective: This case is a patient with tongue myokymia following radiation therapy 12 years earlier, documented using video and EMG. Case report: A 68-year-old woman with a history of nasopharyngeal carcinoma presented with subacute onset of difficulty in speaking and involuntary movements of her tongue approximately 12 years after radiation therapy to head and neck. Electromyography displayed myokymic discharges. There was no evidence of recurrent malignancy. Significance: Delayed effects of radiation therapy might be seen decades later. Myokymic discharges may reveal radiation-induced neuropathy. Keywords: Tongue myokymia, Radiation therapy, Long-term effects
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- 2016
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49. The coexistence of multiple sclerosis and hereditary spastic paraparesis in a patient
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Işıl Yazıcı, Nılufer Yıldırım, and Yaşar Zorlu
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multiple sclerosis, spastin, hereditary spastic paraparesis ,Medicine ,Internal medicine ,RC31-1245 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Multiple sclerosis (MS) is a chronic disease characterized by multiple areas of central nervous system inflammation, demyelination and axonal loss. Hereditary spastic paraparesis (HSP) is characterized clinically by progressive spasticity and weakness of the lower limbs and pathologically by retrograd axonal degeneration of the corticospinal tracts and posterior columns. We identified a patient with clinical history and investigation findings consistent with the concurrence of both MS and HSP. Laboratory and radiological investigations, cognitive tests were performed. Genetic confirmation for spastin gene mutation has been completed. If this coexistence is not coincidence the mutation in the spastin gene may be a strong susceptibility locus for MS.
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- 2013
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50. AN UNUSUAL CASE OF ACQUIRED PARTIAL LIPODYSTROPHY PRESENTING WITH ACANTHOSIS NIGRICANS.
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Kutbay, N. Ozdemir, Yurekli, B. Sarer, Yasar, Z., and Akinci, B.
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ACANTHOSIS nigricans , *ADIPOSE tissues , *ARM , *LIPODYSTROPHY , *FAT , *WOMEN patients - Abstract
About 250 patients with acquired partial lipodystrophy (Barraquer-Simons) syndrome have been reported so far. It is characterized by the loss of adipose tissue from the face and upper extremities, and accumulated fat in the rest of the body. The disease usually starts in females during childhood or adolescence, and usually after a febrile illness. Fat loss often comes into view in months or years. We present a 23-year-old female patient with acquired partial lipodystrophy, which is rarely seen. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
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